具代表性研究發表

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年度 論文名稱
2026 Zhang T, Huang CJ, Chen HT, Huang YH, Pan MH, Lee MH, Viard M, Hildesheim A, Pfeiffer RM, Carrington M, Chen CJ, Zhu B, Lenz TL, Jiang D*, (Yang HI*, Liu Z, HLA-DQB1*03:01 and risk of Hepatitis B virus-related hepatocellular carcinoma., HEPATOLOGY, vol. 83 (2), 374-386, 2026
2026 Tseng TC, Hosaka T, Pan MH, Liu CJ, Suzuki F, Chen CJ, Su TH, Kumada H, Yang WT, Yang HC, Liu CH, Chen PJ, (Yang HI*, Kao JH*, Higher level of Hepatitis B Surface antigen associated with delayed development of hepatocellular carcinoma in immune-tolerant patients., HEPATOLOGY, vol. 83 (1), 142-155, 2026
2025 Liao KS, Zhou Y, Chung C, Kung CC, (Ren CT, Wu CY, Lou YW, Chuang PK, Imre B, Hsieh YSY, Wong CH*, Chemical and Enzymatic Synthesis of DisialylGb5 and Other Sialosides for Glycan Array Assembly and Evaluation of Siglec-Mediated Immune Checkpoint Inhibition., Molecules (Basel, Switzerland), vol. 30(11), 2025
2025 Chan MH*, Zhuang RE, Wei DH*, (Hsiao M, Biomimetic red blood cell membrane-coated FePt metal-organic framework nanoparticles: a multifunctional theranostic system for enhanced MRI and targeted therapy., Nanoscale, vol. 17(40), 23343-23353, 2025
2025 Chuang PK, Chung C, Liao KS, (Wong CH)*, Improving the efficacy of anti-SSEA4 antibody in pancreatic cancer immunotherapy with glyco-optimization and immune checkpoint blockade., Proceedings of the National Academy of Sciences of the United States of America, vol. 122(38), e2517415122, 2025
2025 Lin KY, Jiang JK, Lai JI, Lin SY, Ku YC, Lin MH, Yang CY, Lo LC, (Hsu TL, Chang YC*, Siglec-14-LGALS3BP glycoimmune axis shapes tumor-associated macrophage polarization and confers poor outcome in colorectal cancer., NPJ precision oncology, vol. 9(1), 398, 2025
2025 Bagheri N, Margvelani G, Chiang TW, Nelson PT, (Chuang TJ, Stamm S*, Circular RNAs from the MAPT and TARDBP genes: Novel players in neurodegeneration?, Neurochemistry international, vol. 189, 106019, 2025
2025 Hong MX, Wang BW, Lo LH, Jayalath GED, Lin WT, Yang YL, Tseng SP, Chen YH, Tsai WC, (Cheng WC, Liaw CC*, Pseudopeptides of Marine Vibrio spp. from Taiwan and Their Combined Treatment Effects with Commercial Antibiotics., Planta medica, vol. 91(6-07), 371-381, 2025
2025 Wang CP*, Yu KJ, Chen TC, Tsai MS, Kang CJ, Chien CY, Engels EA, Hua CH, Hsu WL, Chang YL, Dawsey SM, Wentzensen N, Shi J, Mao F, Cheung LC, Katki HA, Boyd E, Wu CT, Gutkind JS, Molinolo A, Limbach AL, Lingen MW, Lou PJ, (Chen CJ, Hildesheim A, Chaturvedi AK, Multistate oral carcinogenesis-A prospective cohort study and a parallel case-control study in Taiwan., Oral oncology, vol. 162, 107210, 2025
2025 Liu CH, Yang ST, Chao WT, Lin CH, Lee YC, Lai CR, (Hsieh SL, Wang LW, Wang PH*, Targeting the ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) as a potential therapeutic strategy to overcome anti-VEGF resistance in endometrial cancer., International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, vol. 171(3), 1343-1354, 2025
2025 Liao TL*, Chen DY, (Hsieh SL, Yang YY, Chen YM, Tang KT, Chang CH, Yang SS, Platelet-derived mitochondria regulate lipid metabolism in nonalcoholic steatohepatitis through extracellular vesicles., Hepatology (Baltimore, Md.), vol. 82(3), 722-738, 2025
2025 Peng HY, Chang CW, Wu PH, Li LJ, Lin YL, (Hsiao M, Chang JY, Chang PM, Lee HL*, Chang WM*, Oral Cancer-Derived miR-762 Suppresses T-Cell Infiltration and Activation by Horizontal Inhibition of CXCR3 Expression., International journal of molecular sciences, vol. 26(3), 1077, 2025
2025 Chung SY, Yeh YC, Huang CJ, Chiang NJ, Hsu DS, Chan MH, Lu ML, Hsu TS, Hung YP, Yeh CN, (Hsiao M, Chang YC, Wang YC, Chen MH*, Comparative impact of tertiary lymphoid structures and tumor-infiltrating lymphocytes in cholangiocarcinoma., Journal for immunotherapy of cancer, vol. 13(1), e010173, 2025
2025 Shimabukuro J, Shen CH, Hsueh TK, Chen TW, Tseng YC, Gannedi V, Dumalaog JS, Chang CH*, (Cheng TR)*, Yu CS*, Hung SC*, Streamlined Synthesis and Immunomodulatory Effects of Ulvan Oligosaccharides from Marine Green Algae., Journal of the American Chemical Society, vol. 147(36), 32951-32962, 2025
2025 Huang YT, Hsu YC, (Yang HI, Lee MH, Lai TH, Chen CJ, Huang YT*, Causal Mediation Analyses for the Natural Course of Hepatitis C: A Prospective Cohort Study., Journal of epidemiology, vol. 35(1), 21-29, 2025
2025 Cao Jie-Ling, Guo Jie-He, Leung Will, Liu Ya-Ting, Tsai I-Lin, Huang Shu-Ling, (Wang Yi-Sheng)*, Lai Yin-Hung*, Do phenolic contents relate to their in-vitro cytotoxicity against colorectal cancer cell lines from Calvatia lilacina (puffball mushroom)?, Food Bioscience, vol. 66, 106193, 2025
2025 Shen Z, Liu Z, Wang H, Landrock D, Noh JY, Zang QS, (Lee CH, Farnell YZ, Chen Z, Sun Y*, Fructose induces inflammatory activation in macrophages and microglia through the nutrient-sensing ghrelin receptor., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol. 39(4), e70412, 2025
2025 Chang YC, Hsieh ML, Lee HL, Hee SW, Chang CF, Yen HY, Chen YA, Chen YR, Chou YW, Li FA, Ke YY, Chen SY, Hung MS, Hung AF, Huang JY, Chiu CH, Lin SY, Shih SF, Hsu CN, Hwang JJ, Yeh TK, Cheng TR, Liao KC, Laio D, Lin SW, Chen TY, (Hu CM, Vogel U, Saar D, Kragelund BB, Tsou LK*, Tseng YH*, Chuang LM*, Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity., EMBO molecular medicine, vol. 17(5), 938-966, 2025
2025 Lin JS, Tzeng ZH, Dumalaog JS, (Hung SC)*, A streamlined synthetic approach to the truncated linear trisaccharide fragment of QS-21., Frontiers in Chemistry, vol. 13, 1650302, 2025
2025 Jackson SS*, Francis J, Pfeiffer RM, Proietti C, Coghill AE, Yu KJ, Sarathkumara YD, Hsu WL, Argirion I, Wang CP, (Chen CJ, Rothman N, Lan Q, Hildesheim A, Doolan DL, Liu Z, Sex Differences in Anti-Epstein-Barr Virus Antibody Responses., The Journal of infectious diseases, vol. 232(4), e671-e675, 2025
2025 Blechter B*, Hsiung CA*, Wang X, Zhang H, Seow WJ, Shi J, Chatterjee N, Kim HN, Wong MP, Hong YC, Wong JYY, Dai J, Hosgood HD, Wang Z, Chang IS, Choi J, Wang J, Song M, Hu W, Zheng W, Kim JH, Zhou B, Albanes D, Shin MH, Chung LP, An SJ, Zheng H, Yatabe Y, Zhang XC, Kim YT, Shu XO, Kim YC, Vermeulen RCH, Bassig BA, Chang J, Man Ho JC, Ji BT, Kubo M, Daigo Y, Momozawa Y, Kamatani Y, Honda T, Kunitoh H, Watanabe SI, Miyagi Y, Nakayama H, Matsumoto S, Tsuboi M, Goto K, Yin Z, Takahashi A, Goto A, Minamiya Y, Shimizu K, Tanaka K, Wu T, Wei F, Su J, Kim YH, Oh IJ, Fun Lee VH, Su WC, Chen YM, Chang GC, Chen KY, Huang MS, Lin HC, Seow A, Park JY, Kweon SS, (Chen CJ, Gao YT, Wu C, Qian B, Lu D, Liu J, Jeon HS, Hsiao CF, Sung JS, Tsai YH, Jung YJ, Guo H, Hu Z, Chen TY, Burdett L, Yeager M, Hutchinson A, Berndt SI, Wu W, Wang J, Choi JE, Park KH, Sung SW, Liu L, Kang CH, Chen CH, Xu J, Guan P, Tan W, Wang CL, Loon Sihoe AD, Chen Y, Choi YY, Kim JS, Yoon HI, Cai Q, Park IK, Xu P, He Q, Chen CY, Wu J, Lim WY, Chen KC, Chan JKC, Li J, Chen H, Yu CJ, Jin L, Fraumeni JF Jr, Liu J, Landi MT, Yamaji T, Yang Y, Hicks B, Wyatt K, Li SA, Ma H, Song B, Wang Z, Cheng S, Li X, Ren Y, Iwasaki M, Zhu J, Jiang G, Fei K, Wu G, Chien LH, Tsai FY, Yu J, Stevens VL, Yang PC, Lin D, Chen K, Wu YL, Matsuo K, Rothman N, Shiraishi K, Shen H, Chanock SJ, Kohno T, Lan Q, Polygenic Risk Score and Lung Adenocarcinoma Risk Among Never-Smokers by EGFR Mutation Status: A Brief Report., Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, vol. 20(4), 521-530, 2025
2025 Chen CJ)*, Wu CC, Wei SL, Lin LJ, Lee WC, Chiang CJ, Chien RN, Lu SN, National strategy for elimination of liver diseases in Taiwan., Journal of the Formosan Medical Association = Taiwan yi zhi, vol. 124 Suppl 2, S74-S83, 2025
2025 Lu SN, Wang JH, (Chen CJ)*, Changing epidemiology of hepatitis C virus infection and liver disease mortality in Taiwan., Journal of the Formosan Medical Association = Taiwan yi zhi, vol. 124 Suppl 2, S96-S101, 2025
2025 Huang YT, Hsu YC, Yang HI, Lee MH, Lai TH, (Chen CJ, Huang YT*, Causal Mediation Analyses for the Natural Course of Hepatitis C: A Prospective Cohort Study., Journal of epidemiology, vol. 35(1), 21-29, 2025
2025 Lee S, Ahn C, Abe SK, Rahman MS, Islam MR, Saito E, An S, Sawada N, Shu XO, Koh WP, Cai H, Hozawa A, Kanemura S, Nagata C, You SL, Kang D, Kanehara R, Gao YT, Yuan JM, Wen W, Sugawara Y, Wada K, (Chen CJ, Yoo KY, Ahsan H, Chia KS, Shin A, Kim J, Lee JE, Matsuo K, Rothman N, Qiao YL, Zheng W, Boffetta P, Inoue M, Park SK*, Association Between Cardiometabolic Multimorbidity and 15-year Mortality in the Asia Cohort Consortium., Journal of epidemiology, vol. 35(7), 321-329, 2025
2025 Liao PJ, (Chen CJ, Seak CJ, Ting MK, Hsu KH*, Antagonistic effect of arsenic exposure and chronic hepatitis viral infection on hepatocellular carcinoma., Journal of the National Cancer Institute, vol. 117(11), 2372-2381, 2025
2025 Peng HY, Huang YL, Wu PH, Li LJ, Peng BY, Wu CY, Lin YL, (Hsiao M, Chang JY, Mu-Hsin Chang P, Lee HL, Chang WM*, The miR-876-5p/SOCS4/STAT3 pathway induced the expression of PD-L1 and suppressed antitumor immune responses., Cancer cell international, vol. 25(1), 114, 2025
2025 Ding YF, Ho KH, Lee WJ, Chen LH, Hsieh FK, Tung MC, Lin SH, (Hsiao M, Yang SF, Yang YC*, Chien MH*, Cyclic increase in the histamine receptor H1-ADAM9-Snail/Slug axis as a potential therapeutic target for EMT-mediated progression of oral squamous cell carcinoma., Cell death & disease, vol. 16(1), 191, 2025
2025 Chen SH*, Wu SY, Chang YX, Lui EN, Chang CK, Lin SW, (Hsiao M, Yang JM, Liang PH*, Blocking XIAP:CASP7-p19 selectively induces apoptosis of CASP3/DR malignancies by a novel reversible small molecule., Cell death & disease, vol. 16(1), 459, 2025
2025 Yang YF, He ZJ, Kuo HH, Lin YY, Kim CH, Cai HY, Chen CL, (Hsiao M, Chen YC, Chang PM*, Chang YC*, Targeting ESR1 restores SQSTM1-dependent autophagy and sensitizes ER-positive breast cancer to oxidative and radiation stress., Cell death discovery, vol. 11(1), 451, 2025
2025 Pan KF, Chou HL, Wang WL, Chen BR, (Hsiao M, Hua KT*, Wu MH*, KSRP-mediated Wnt/beta-catenin activation promotes follicular thyroid cancer progression and stemness., British Journal of Cancer, vol. 133(8), 1111-1121, 2025
2025 Yesian AR, Chalom MM, Knudsen NH, Hyde AL, Personnaz J, Cho H, Liou YH, Starost KA, Lee CW, Tsai DY, Ho HW, Lin JS, Li J, Hu FB, Banks AS, (Lee CH)*, Preadipocyte IL-13/IL-13Rα1 signaling regulates beige adipogenesis through modulation of PPARγ activity., The Journal of Clinical Investigation, vol. 135(11), e169152, 2025
2025 Chen CC, Hung TM, Huang YJ, Hung HS, (Hu CM, Lee PH, Tacrolimus regulates extracellular vesicle secretion from T cells via autophagy-lysosomal pathway., Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, vol. 182, 117765, 2025
2025 Li HY*, Perez SJLP, Chang HL, Lo HH, Yang CN*, (Cheng WC)*, Design and synthesis of polyhydroxylated azabicyclo[3.3.1]nonane as selective lysosomal alpha-glucosidase stabilizers enhancing cellular uptake., Bioorganic Chemistry, vol. 165, 108994, 2025
2025 Kudo M, Oanh BT, (Chen CJ, Ngat DT, George J, Kim DY, Pimsawadi L, Tangkijvanich P, Pwu RF, Mohamed R, Bunnag S, Lu SN, Kudtiyakarn S, Kanto T, Piratvisuth T, Wu CC, Sarno R*, Roadmap for HCC Surveillance and Management in the Asia Pacific., Cancers, vol. 17(12), 1928, 2025
2025 Liu PT, Hsu WL, Chen TI, Chiang CJ, Pan MH, Lee HL, Wang CC, (Chen CJ, Wang V*, Chen YC*, Association Between Human Papillomavirus and Thymic Cancer: A Population-Based Cohort Study., Cancer management and research, vol. 17, 2023-2033, 2025
2025 Li IC, Chan YL, Lu WT, Chiang LH, Li TJ, Li TL, Chen CC*, Wu CJ*, Phellinus linteus Mycelia Extracts Show Potent Antiviral and Immunomodulatory Effects in H1N1 Influenza Virus Infected Mice, FOODS, vol. 14(23), 4047, 2025
2025 Khatoon Z, Anandharaj M, Chen TH, Wu CC, Cheng JF, Hsu TL, Lin HC, Chang JJ, Li WH, Creating a large designer cellulosome in yeast to boost ethanol production., Proceedings of the National Academy of Sciences of the United States of America, vol. 122(45), e2517490122, 2025
2025 Ali Farhan, Yi-Sheng Wang*, Recent applications of artificial intelligence and related technical challenges in MALDI MS and MALDI-MSI – A mini review, Mass Spectrometry (MSSJ), vol. 14 (1), A0175-A0175, A0175-A0175, 2025
2025 Liang Yu-Jen, Yang Chih-Ting, Chen Chia-Wei, Lin Yin-Chun, Lin Shu-Yao, Wang Yi Sheng, Yang Hsin-Chou*, SMART 2.0 Statistical Metabolomics Analysis: An R Tool 2.0, Analytical Chemistry, 2025
2025 Yi-Hong Cai, Yi-Sheng Wang*, Theoretical Study of High-Order Velocity Focusing Achieved with Single-Stage Reflectron Time-of-flight Mass Spectrometry, Journal of the American Society for Mass Spectrometry, 2025
2025 Hsiao Wan-Yi, Yeh Chung-Shu, Liu Hsin-I, Tung Luh, (Chang Tien-Hsien*, Genome-wide screen uncovers novel host factors for L-A virus maintenance and a potential mutualistic-symbiosis relationship in yeast, BMC Microbiology, vol. 25(1), 2025
2025 Selvaraj SP, Chang JC, Raja K, Zsu JT, Hazam PK, Lin WC, Huang JR*, Li TL*, Chen JY*, Novel self-assembled antimicrobial peptide Pardaxin hydrogel as a functional biomaterial for food packaging and preservation, CHEMICAL ENGINEERING JOURNAL, vol. 525, 170727, 2025
2025 Songtao Dong(#, Soohwan An(#, Qimanguli Saiding, Qian Chen, Bin Liu, Na Kong, Wei Chen*, Wei Tao*, Therapeutic Hydrogels: Properties and Biomedical Applications, Chemical Reviews, vol. 125, 8835-8920, 2025
2025 Zhongshan He, Yaoyao Luo, Zhonghui Duan, Bin Su, Wanqin Zeng, Yu Guo, Yongjiang Li, Xi He, Haixing Shi, Zhuoming Zhou, Chunling Jiang, Duotian Qin, Ji Zhang, Yan Kang*, Wei Chen*, Xiangrong Song*, IRF5 siRNA Nanoimmunotherapy: Restoring Macrophage Efferocytosis in Atherosclerosis, Circulation, vol. doi.org/10.1161/CIRCULATIONAHA.125.075352, In press, 2025
2025 Yiming Zhang, Zhuoming Zhou, Tian Hao, Shuying Chen, Wei Luo, Muhammad Muzamil Khan, Yesi Shi, Xinru You, Qimanguli Saiding, Xueyan Zhen, Wei Tao, * Tian Xie, * Wei Chen, * Na Kong*, “Cancer-Treating-Cancer” Strategy: Entrapping Engineered Dying Cancer Cells in Immunotherapeutic Hydrogel Against Tumor Recurrence, Cell Biomaterials, 2025
2025 Li TH, Yeh HY, Lin SW, Huang YS, Zhuo ZW, Ma CC, Hsu TL, Wu WK, Tsai HC, Shen HC, Su CW, Yang YY, Lin HC, Hou MC, Adenosine A2AR agonist blocks mesenteric lymphatic epithelium, adipose tissue and Treg cells links of metabolic dysfunction-associated steatotic liver disease mice., Molecular and cellular endocrinology, vol. 610, 112667-112678, 2025
2025 Y. L. Chan*, Y. P. Chao, T. L. Li, K. W. Liao, Chitosan-based Oral DNA vaccine elicits mucosal immunity and reduces Helicobacter pylori colonization in mice, VACCINE, vol. 64, 127692, 2025
2025 Wei-Chien Weng, Hung-En Liao, Cheng-Hsiu Chang, (Shang-Cheng Hung, Kai Du, Zhijay Tu, Chun-Hung Lin, Chi-Kung Ni*, Unusual Free Trisaccharides in Caprine Colostrum Discovered by Logically Derived Sequence Tandem Mass Spectrometry, SCIENTIFIC REPORTS, vol. 15, 1586, 2025
2025 Ahmed Atito, Jasper S. Dumalaog, Kuei-Yao Tseng, Yen-Ju Ting, Medel Manuel L. Zulueta, (Shang-Cheng Hung*, Molecular Iodine-Mediated β-Glycosylation of Thiomannosides with 1,6-Anhydrosugars, ORGANIC LETTERS, vol. 27, 2450-2455, 2025
2025 Yi-Cheng Tsai, Chien-Jui Huang, Jui-Lin Chang, Nai-Jung Chiang, Yu-Shan Huang, Anandaraju Bandaru, (Shang-Cheng Hung*, Yan-Shen Shan*, Gwo-Bin Lee*, Application of CAPTURE Assay for Early Diagnosis and Prognosis in Bile and Blood of Cholangiocarcinoma, JCO PRECISION ONCOLOGY, vol. 9, e2400728, 2025
2025 Libor Hejduk, Norbert Müller, Adriana Rathner, Ján Štěrba, (Shang-Cheng Hung, Chia-Lin Chyan, Ryan O. M. Rego*, Martin Strnad*, Navigating Infection by Pathogenic Spirochetes: The Host-Bacteria Interface at the Atomic Level, PROTEIN SCIENCE, vol. 34, e70185, 2025
2025 Junpei Shimabukuro, Ci-Hua Shen, Tsung-Kai Hsueh, Ting-Wen Chen, Yin-Chen Tseng, Veeranjaneyulu Gannedi, Jasper S. Dumalaog, Cheng-Hsiu Chang, * Ting-Jen Rachel Cheng, * Chung-Shan Yu, * (Shang-Cheng Hung*, Streamlined Synthesis and Immunomodulatory Effects of Ulvan Oligosaccharides from Marine Green Algae, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025
2025 Yeh HY, Pan MH, Huang CJ, Hong SY, (Yang HI*, Yang YY, Huang CC, Tsai HC, Li TH, Su CW, Hou MC, Triglyceride-glucose index and cancer risk: a prospective cohort study in Taiwan., DIABETOLOGY & METABOLIC SYNDROME, vol. 17(1), 283, 2025
2025 Tseng TC, Hsu YC, Su TH, Liu CH, Wang CC, Lin CL, (Yang HI, Huang YH, Yang SS, Peng CY, Hu TH, Huang JF, Kao JH, Expert consensus on clinical usefulness of M2BPGi for managing chronic liver diseases., JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, vol. S0929-6646(25)00441-3, doi: 10.1016/j.jfma.2025.08.022, 2025
2025 Chen Hsu, Hsin-Ya Tsai, Sheng-Dong Chen, Chi-Fon Chang, Nan-Wei Su*, Molecular Insights into a Promiscuous Dikinase Catalyzing Monophosphorylation of Structurally Diverse Natural Polyphenols, ACS Catalysis, vol. 15, 13179-13191, 2025
2025 Wittke CI, Cheung EC, Athineos D, Clements N, Butler L, Hughes M, Morrison V, Watt DM, Blyth K, Vousden KH, Humpton TJ, p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis., JHEP reports : innovation in hepatology, vol. 7(7), 101397, 2025
2025 J. M. Lo, C.-C. Kung, T.-J., C.-H. Wong, C. Ma, Structure-Based Mechanism and Specificity of Human Galactosyltransferase β3GalT5, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 147, 10875-10885, 2025
2025 C.-C. Kung, J. Lo, K.-S. Liao, C.-Y. Wu, L.-C. Cheng, C. Chung, T.-L. Hsu, C. Ma, C.-H. Wong, Expression of Human β3GalT5-1 in Insect Cells as Active Glycoforms for the Efficient Synthesis of Cancer-Associated Globo-Series Glycans, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 147, 10864-10874, 2025
2025 R. Li, P. Chen, Y.-F. Zeng, T.-H. Tseng, V. Gannedi, L. Krasnova, C.-H. Wong, Expedient Assembly of Multiantennary N-Glycans from Common N-Glycan Cores with Orthogonal Protection for the Profiling of Glycan-Binding Proteins., Journal of the American Chemical Society, vol. 147(15), 12937-12948, 2025
2025 K.-S. Liao, Y. Zhou, C. Chung, C.-C. Kung, C.-T. Ren, C.-Y. Wu, Y.-W. Lou, P.-K. Chuang, B. Imre, Y.S.Y. Hsieh, C.-H. Wong, Chemical and Enzymatic Synthesis of DisialylGb5 and Other Sialosides for Glycan Array Assembly and Evaluation of Siglec-Mediated Immune Checkpoint Inhibition., Molecules (Basel, Switzerland), vol. 30(11), 2264, 2025
2025 H.-W. Huang, Y.-F. Zeng, V. S. Shivatare, T.-H. Tseng, C.-H. Wong, Cell-based glycoengineering for production of homogeneous and specific glycoform enriched antibodies with improved effector functions, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 122 (8), e2423853122, 2025
2025 M. Usama, Y.-C. Hsu, M. Safaei, C.-Y. Chen, K.-H. Han, Y.-S. Ho, H. Yamaguchi, Y.-C. Li, M.-C. Hung, C.-H. Wong, C.-W. Lin, Antibody-drug conjugates targeting SSEA-4 inhibits growth and migration of SSEA-4 positive breast cancer cells., Cancer letters, vol. 611, 217453, 2025
2025 Kung CC, Lo JM, Liao KS, Wu CY, Cheng LC, Chung C, Hsu TL, Ma C, Wong CH, Expression of Human beta3GalT5-1 in Insect Cells as Active Glycoforms for the Efficient Synthesis of Cancer-Associated Globo-Series Glycans., Journal of the American Chemical Society, vol. 147(13), 10864-10874, 2025
2025 Chang YC, Hsieh ML, Lee HL, Hee SW, (Chang CF, Yen HY, Chen YA, Chen YR, Chou YW, Li FA, Ke YY, Chen SY, Hung MS, Hung AF, Huang JY, Chiu CH, Lin SY, Shih SF, Hsu CN, Hwang JJ, Yeh TK, Cheng TR, Liao KC, Laio D, Lin SW, Chen TY, Hu CM, Vogel U, Saar D, Kragelund BB, Tsou LK, Tseng YH, Chuang LM, Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity., EMBO molecular medicine, vol. 17(5), 938-966, 2025
2025 Chen CL, Yang WS, (Yang HI, Chen CF, Wang LY, Lu SN, Kao JH, Chen PJ, Chen CJ, Plasma Adiponectin Levels in Relation to Chronic Hepatitis B Infection Progression to Liver Cancer Milestones: A Prospective Study., LIVER CANCER, vol. 14(1), 19-35, 2025
2025 Tseng TC, Huang SC, Pan MH, Liu CJ, Chen CJ, Yang WT, Tsai CH, Su TH, Yang HC, Liu CH, Chen PJ, (Yang HI*, Kao JH*, Hepatitis B surface antigen level identifies patients with inactive chronic hepatitis B from Asia with HCC risk below surveillance threshold., GUT, vol. gutjnl-2025-334911, doi: 10.1136/gutjnl-2025-334911, 2025
2025 Huang YT, Hsu YC, (Yang HI, Lee MH, Lai TS, Chen CJ, Huang YT, Corrigendum: "Causal Mediation Analyses for the Natural Course of Hepatitis C: A Prospective Cohort Study" [J Epidemiol 35(1) (2025) 21-29]., JOURNAL OF EPIDEMIOLOGY, vol. doi: 10.2188/jea.JE20250177., Online ahead of print., 2025
2025 Li TH, Huang YS, Ma CC, Tsai SY, Tsai HC, Yeh HY, Shen HC, Hong SY, Su CW, (Yang HI*, Yang YY*, Hou MC, GCKR Polymorphisms Increase the Risks of Low Bone Mineral Density in Young and Non-Obese Patients With MASLD and Hyperuricemia., KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, 2025
2025 Li H, Chiang CL, Kwak KJ, Lee HL, Wang X, Romano G, Saviana M, Toft R, Cheng TS, Chang Y, Hsiang BD, Liu GW, Mo X, Ma Y, Pan J, Rima XY, Kim TN, Reategui E, (Shen CN, Chu YS, Croce C, Chang PM, Yeh YC, Carbone DP, Huang CF, Chiang CL, Nana-Sinkam P, Lee LJ, Extracellular Vesicular Delta-Like Ligand 3 and Subtype Transcription Factors for Small Cell Lung Cancer Diagnosis., Advanced Science, vol. doi: 10.1002/advs.202416711., Online ahead of prin, 2025
2025 Lee C.Y., T.C. Kuo, Y.H. Chou, S.J. Peng, F.T. Hsiao, M.H. Chung, L.W. Lo, (C.N. Shen, H.J. Chien, H.P. Chang, C. C. Chen, Y.M. Jeng, Y.W. Tien, S.C. Tang., 3D imaging resolves human pancreatic duct-β-cell clusters during cystic change, Diabetes, vol. 74(5), 734-748, 2025
2025 Lo JM., Kung CC, Cheng TJR, Wong CH*, (Ma C*, Structure-Based Mechanism and Specificity of Human Galactosyltransferase β3GalT5, Journal of the American Chemical Society, vol. 147(13), 10875-10885, 2025
2025 Kung CC, Lo JM., Liao KS, Wu CY, Cheng LC, Chung C, Hsu TL, (Ma C)*, Wong CH*, Expression of Human β3GalT5–1 in Insect Cells as Active Glycoforms for the Efficient Synthesis of Cancer-Associated Globo-Series Glycans, Journal of the American Chemical Society, vol. 147(13), 10864-10874, 2025
2025 Liu, P.-C., Huang, S.-Y., (Lin, K.-I, Hsieh, S.-L, Leu, C.-M., Suppression of NF-κB and downstream XBP1 by DcR3 contributes to a decrease in antibody secretion, JOURNAL OF IMMUNOLOGY, vol. 214, 72-84, 2025
2025 Enkhbayar, B., Lu, S.-C., Tsai, H.-Y., Liang, S.-Y., Wu, S.-J., (Lin, K.-I, Angata, T., Insights into the transcriptional regulation of CD22 in B cell chronic lymphocytic leukemia., Journal of Biological Chemistry, vol. 108386, 108386, 2025
2025 Y. L. Chan, J. C. Liao, T. L. Li, C. J. Wu*, Y. H. Chiu*, Bifidobacterium lactis ameliorates AOM/DSS‑induced inflammation, dysbiosis, and colonic precancerous lesions, APPLIED MICROBIAL AND CELL PHYSIOLOGY, vol. 109 (69), 1-15, 2025
2025 H. T. Huang, C. T. Chiou, Y. C. Lin, L. J. Zhang, C. H. Chao, P. J. Sung, J. J. Chen, T. L. Li, I. W. Lo*, C. C. Liaw*, Potential Anti-H1N1 Schtriterpenoids from Kadsura japonica L. Vines, PHYTOCHEMISTRY, vol. 240, 114632, 2025
2025 Hu CM*, Tien SC, Lo YC, Huang CH, Ko YL, Wu DN, Lee JH, Wu YT, Yu HM, Ling KG, Lee ZY, Cheng WC, Innovative cyclic peptide disrupts IL-17RB-MLK4 interaction for targeted pancreatic cancer therapy, Biomedicine & Pharmacotherapy, vol. 184, 117892, 2025
2025 Tien SC, Shih M, Hu CM, RRM1 O-GlcNAcylation inhibition suppresses pancreatic cancer via TK1-mediated replication stress., Cancer gene therapy, vol. 32(5), 550-562, 2025
2025 Ya-Ling Chiang, Yu-Jen Chang, (Yun-Ru Chen, Ing-Shouh Hwang*, Evidence Supporting Enrichment of Dissolved Air Gases near Hydrophobic Macromolecules in Aqueous Solutions, Langmuir, vol. 41(1), 285-291, 2025
2025 Gary Jen-Wei Chen§, Ming-Yun Chang§, Xin-Peng Lin, Debapriya Kundu, Yu-Jen Chang, Yun-Ru Chen)*, Tau destabilization in a familial deletion mutant K280 accelerates its fibrillization and enhances the seeding effect, JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 301(2), 108184, 2025
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2025 Chia-Yi Ho, Yu-Jen Chang, Chih-Wen Yang, Orion Shih, U-Ser Jeng, Wan-Chen Huang, Ing-Shouh Hwang, (Yun-Ru Chen)*, Membrane disruption properties of poly-glycine arginine dipeptide repeats affected by peptide repeats continuity and membrane composition, Journal of Molecular Biology, 2025
2025 Zhuoming Zhou, Wei Chen*, Yihai Cao, Reza Abdi, Wei Tao*, Nanomedicine-based Strategies for the Treatment of Vein Graft Disease, Nature Reviews Cardiology, vol. 22, 255-272, 2025
2025 Shuying Chen†, Yongjiang Li†, Zhuoming Zhou, Qimanguli Saiding, Yiming Zhang, Soohwan An, Muhammad Muzamil Khan, Xiaoyuan Ji, Ruirui Qiao, Wei Tao*, Na Kong*, Wei Chen*, Tian Xie*, Macrophage hitchhiking nanomedicine for enhanced β-elemene delivery and tumor therapy, Science Advances, vol. 11, eadw7191, 2025
2025 Chen CL*, Yang WS, Yang HI, Chen CF, Wang LY, Lu SN, Kao JH, Chen PJ, (Chen CJ, Plasma Adiponectin Levels in Relation to Chronic Hepatitis B Infection Progression to Liver Cancer Milestones: A Prospective Study, Liver Cancer, vol. 14 (1), 19-35, 2025
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2025 Y. L. Chan, J. C. Liao, T. L. Li, C. J. Wu*, Y. H. Chiu*, Bifidobacterium lactis ameliorates AOM/DSS‑induced inflammation, dysbiosis, and colonic precancerous lesions, APPLIED MICROBIAL AND CELL PHYSIOLOGY, vol. 109 (69), 1-15, 2025
2025 Li TH, Huang YS, Ma CC, Tsai SY, Tsai HC, Yeh HY, Shen HC, Hong SY, Su CW, (Yang HI*, Yang YY*, Hou MC, GCKR Polymorphisms Increase the Risks of Low Bone Mineral Density in Young and Non-Obese Patients With MASLD and Hyperuricemia., KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, 2025
2025 Huang YT, Hsu YC, (Yang HI, Lee MH, Lai TS, Chen CJ, Huang YT, Corrigendum: "Causal Mediation Analyses for the Natural Course of Hepatitis C: A Prospective Cohort Study" [J Epidemiol 35(1) (2025) 21-29]., JOURNAL OF EPIDEMIOLOGY, vol. doi: 10.2188/jea.JE20250177., Online ahead of print., 2025
2025 Tseng TC, Huang SC, Pan MH, Liu CJ, Chen CJ, Yang WT, Tsai CH, Su TH, Yang HC, Liu CH, Chen PJ, (Yang HI*, Kao JH*, Hepatitis B surface antigen level identifies patients with inactive chronic hepatitis B from Asia with HCC risk below surveillance threshold., GUT, 2025
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2025 Zhang T, Huang CJ, Chen HT, Huang YH, Pan MH, Lee MH, Viard M, Hildesheim A, Pfeiffer RM, Carrington M, Chen CJ, Zhu B, Lenz TL, Jiang D*, (Yang HI*, Liu Z, HLA-DQB1*03:01 and risk of Hepatitis B virus-related hepatocellular carcinoma., HEPATOLOGY, vol. doi: 10.1097/HEP.0000000000001307, Online ahead of print, 2025
2025 Chen CL, Yang WS, (Yang HI, Chen CF, Wang LY, Lu SN, Kao JH, Chen PJ, Chen CJ, Plasma Adiponectin Levels in Relation to Chronic Hepatitis B Infection Progression to Liver Cancer Milestones: A Prospective Study., LIVER CANCER, vol. 14(1), 19-35, 2025
2024 Cheung EC, Strathdee D, Stevenson D, Coomes J, Blyth K, Vousden KH, Regulation of ROS signaling by TIGAR induces cancer-modulating responses in the tumor microenvironment., Proceedings of the National Academy of Sciences of the United States of America, vol. 121(50), e2416076121, 2024
2024 Furuya H, Nguyen CT, Chan T, Marusina AI, Merleev AA, Garcia-Hernandez ML, (Hsieh SL, Tsokos GC, Ritchlin CT, Tagkopoulos I, Maverakis E, Adamopoulos IE*, IL-23 induces CLEC5A(+) IL-17A(+) neutrophils and elicit skin inflammation associated with psoriatic arthritis., Journal of autoimmunity, vol. 143, 103167, 2024
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2024 Chang CM, Chang WC*, (Hsieh SL)*, Characterization of the genetic variation and evolutionary divergence of the CLEC18 family., Journal of biomedical science, vol. 31(1), 53, 2024
2024 Tsui KH, Liu CL, Yeh HL, Liu MK, Li CH, Chen WH, Jiang KC, Li HR, Thuy Dung PV, (Hsiao M, Abou-Kheir W, (Liu YN, WNT1-inducible signaling pathway protein 1 activation through C-X-C motif chemokine ligand 5/C-X-C chemokine receptor type 2/leukemia inhibitory factor/leukemia inhibitory factor receptor signaling promotes immunosuppression and neuroendocrine differentiation in prostate cancer., iScience, vol. 27(8), 110562, 2024
2024 Ho Chiu-Yi, Sun Gwo-Ching, Lin Yu-Te, Wong Tzyy-Yue, (Hsiao Michael, Tseng Ching-Jiunn, Cheng Pei-Wen, Microglial Activation and Toll-like Receptor 4-Dependent Regulation of Angiotensin II Type I Receptor-mu-opioid Receptor 1 Heterodimerization and Hypertension in Fructose-fed Rats, EUROPEAN JOURNAL OF PHARMACOLOGY, vol. Jan5:962, 176171, 2024