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s Nucleotide on Bacterial Translocase MraY: Discovery of Unexpected MraY Inhibitors., Scientific reports, vol. 6, 31579, 2016 survival., Blood, vol. 128(12), 1578-89, 2016
年度 論文名稱
2016 Cheung EC, Lee P, Ceteci F, Nixon C, Blyth K, Sansom OJ, Vousden KH, Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine., Genes & development, vol. 30(1), 52-63, 2016
2016 See-Tong Pang, Ying-Hsu Chang, Po-Hung Lin, (Ying-Chih Chang, Yow-sien Lin, Ben Hsieh, Chung-Yi Liu, Cheng-Keng Chuang, Ritu Kamal, Rui Mei*, A Novel biomarker for prostate cancer detection in patient with gray zone PSA level, Urological Science, vol. 27(2), S1-S2, 2016
2016 Si-Hong Lu, Wen-Sy Tsai, Ying-Hsu Chang, Teh-Ying Chou, See-Tong Pang, Po-Hung Lin, Chun-Ming Tsai, Ying-Chih Chang)*, Identifying Cancer Origin Using Circulating Tumor Cells, Cancer Biology & Therapy, vol. 17(4), 430-438, 2016
2016 Jia-Yang Chen, Wen-Sy Tsai, Hung-Jen Shao, Jen-Chia Wu, Jr-Ming Lai, Si-Hong Lu, Tsung-Fu Hung, Chih-Tsung Yang, Liang-Chun Wu, Jinn-Shiun Chen, Wen-Hwa Lee, Ying-Chih Chang, Sensitive and Specific Biomimetic Lipid Coated Microfluidics to Isolate Viable Circulating Tumor Cells and Microemboli for Cancer Detection, PLoS One, vol. 11(3), e0149633, 2016
2016 Ming-Chu Chang, Yu-Ting Chang*, Jia-Yang Chen, Yung-Ming Jeng, Ching-Yao Yang, Yu-Wen Tien, Shih-Hung Yang, Huai-Lu Chen, Ting-Yuan Liang, Chien-Fang Wang, Eva Y.H.P. Lee, (Ying-Chih Chang, Wen-Hwa Lee*, Clinical Significances of Circulating Tumor Microemboli as a Prognostic Marker in Patients with Pancreatic Ductal Adenocarcinoma, CLINICAL CHEMISTRY, vol. 62(3), 505-513, 2016
2016 Wen-Sy Tsai, Jinn-Shiun Chen, Hung-Jen Shao, Jen-Chia Wu, Jr-Ming Lai, Si-Hong Lu, Tsung-Fu Hung, Yen-Chi Chiu, Jeng-Fu You, Pao-Shiu Hsieh, Chien-Yuh Yeh, Hsin-Yuan Hung, Sum-Fu Chiang, Geng-Ping Lin, Reiping Tang, Ying-Chih Chang)*, Circulating Tumor Cell Count Correlates with Colorectal Neoplasm Progression and Is a Prognostic Marker for Distant Metastasis in Non-Metastatic Patients, Scientific Reports, vol. 6, 24517, 2016
2016 Yu Wen Tien, Hsun-Chuan Kuo, Be-Ing Ho, Ming-Chu Chang, Yu-Ting Chang, Mei-Fang Cheng, Huai-Lu Chen, Ting-Yung Liang, Chien-Fang Wang, Chia-Yi Huang, Jin-Yuh Shew, Eva YHP Lee, Wen-Hwa Lee, A High Circulating Tumor Cell Count in Portal Vein Predicts Liver Metastasis From Periampullary or Pancreatic Cancer A High Portal Venous CTC Count Predicts Liver Metastases, MEDICINE, vol. 95(16), e3407, 2016
2016 Ming-Chu Chang, Ying-Chih Chang, Yung-Ming Jeng, Ching-Yao Yang, Yu-Wen Tien, Shih-Hung Yang, Eva Y.H.P. Lee, Wen-Hwa Lee, Yu-Ting Chang, Circulating tumor cluster is a prognostic marker in patients with pancreatic ductal adenocarcinoma, PANCREATOLOGY, vol. 16(4), S53-S53, 2016
2016 • Sachin S Shivatare, Shih-Huang Chang, Tsung-I Tsai, Susan Yu Tseng, Yih-Shyan Lin, Yang-Yu Cheng, Chang-Chun David Lee, Sujeet Pawar, Charng-Sheng Tsai, Hao-Wei Shih, Yi-Fang Zeng, Chi-Hui Liang Peter D. Kwong, Dennis R. Burton, Chung-Yi Wu, * Chi-Huey Wong*, Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies, Nature Chemistry, vol. 8, 338-346, 2016
2016 Li TH, Huang CC, Yang YY, Lee KC, (Hsieh SL, Hsieh YC, Alan L, Lin HC, Lee SD, Tsai CY*, Thalidomide Improves the Intestinal Mucosal Injury and Suppresses Mesenteric Angiogenesis and Vasodilatation by Down-Regulating Inflammasomes-Related Cascades in Cirrhotic Rats, PLoS One, vol. 11(1): e0147212, 1-17, 2016
2016 Tarng DC, Tseng WC, Lee PY, Chiou SH, (Hsieh SL)*., Induced Pluripotent Stem Cell-derived Conditioned Medium Attenuates Acute Kidney Injury by Downregulating the Oxidative Stress-Related Pathway in Ischemia-Reperfusion Rats, CELL TRANSPLANTATION, vol. 25(3), 517-530, 2016
2016 Tung YT, Chang CC, Lin YL, (Hsieh SL, Wang GJ*, Development of double-generation gold nanoparticle chip-based dengue virus detection system combining fluorescence turn-on probes, BIOSENSORS & BIOELECTRONICS, vol. 77, 90-98, 2016
2016 Huang YL, Chen ST, Liu RS, Chen YH, Lin CY, Huang CH, Su PY, Liao CL, (Hsieh SL)*, CLEC5A is Critical for Dengue Virus-induced Osteoclast Activation and Bone Homeostasis, JOURNAL OF MOLECULAR MEDICINE-JMM, vol. 94(9), 1025-1037, 2016
2016 Fan WC, Liu CW, Ou SM, Huang CC, Li TH, Lee KC, Huang SF, Yang YY, Hsieh YC, (Hsieh SL, Hou MC, Lin HC*, TLR4/CD14 Variants-Related Serologic and Immunologic Dys-Regulations Predict Severe Sepsis in Febrile De-Compensated Cirrhotic Patients, PLoS One, vol. 11(11): e0166458, 1-19, 2016
2016 Li TH, Lee PC, Lee KC, Hsieh YC, Tsai CY, Yang YY, Huang SF, Tsai TH, (Hsieh SL, Hou MC, Lin HC, Lee SD*, Down-regulation of common NFκB-iNOS pathway by chronic Thalidomide treatment improves Hepatopulmonary Syndrome and Muscle Wasting in rats with Biliary Cirrhosis, SCIENTIFIC REPORTS, vol. 6: 39405, 1-14, 2016
2016 Cheung SK, Chuang PK, Huang HW, Hwang-Verslues WW, Cho CH, Yang WB, Shen CN, (Hsiao M, Hsu TL, Chang CF, Wong CH, Stage-specific embryonic antigen-3 (SSEA-3) and beta3GalT5 are cancer specific and significant markers for breast cancer stem cells., Proceedings of the National Academy of Sciences of the United States of America, vol. Jan 26;113(4):960-965. Cite 1, 2016
2016 Sung PL, Jan YH, Lin SC, Huang CC, Lin H, Wen KC, Chao KC, Lai CR, Wang PH, Chuang CM, Wu HH, Twu NF, Yen MS, (Hsiao M)*, Huang CF, Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma., Oncotarget, vol. Jan 26;7(4):4036-4047, 2016
2016 Chen CW, Huang JH, Lai TC, Jan YH, (Hsiao M)*, Chen CH, Hwu YK, Liu RS, Evaluation of the intracellular uptake and cytotoxicity effect of TiO2 nanostructures for various human oral and lung cells under dark conditions, Toxicology Research, vol. 5:303-311, 2016
2016 Adebayo BO, Huang WC, Lee WH, Wu AT, Wang LS, (Hsiao M, Yeh CT, Chao TY, Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448, BMC Cancer, vol. Feb 25;16(1):160, 2016
2016 Lin TC, Su CY, Lai TC, Pan WA, Jan YH, Yeh CT, Chen CL, Ger LP, Chang HT, Yang CJ, Huang MS, Shyy JY, Tsai MD, (Hsiao M)*, NIFK promotes cancer metastasis through Runx1-dependent repression of casein kinase 1α to activate Wnt/b-catenin signaling, eLife, vol. Mar 17;5:e11288, Cite 15, 2016
2016 Liu YP, Lee JJ, Lai TC, Lee CH, Hsiao YW, Chen PS, Liu WT, Hong CY, Lin SK, Ping Kuo MY, Lu PJ, (Hsiao M)*, Suppressive function of low-dose deguelin on the invasion of oral cancer cells by downregulating tumor necrosis factor alpha-induced nuclear factor-kappa B signaling., Head and Neck-Journal for the Sciences and Specialties of the Head and Neck, vol. Apr;38 Suppl 1, E524-E534, 2016
2016 Li YJ, Huang TH, (Hsiao M, Lin BR, Cheng SJ, Yang CN, Lai WT, Wu TS, Fan JR, Kuo MY, Chang CC, Suppression of fructose-bisphosphate aldolase C expression as a predictor of advanced oral squamous cell carcinoma., Head and Neck-Journal for the Sciences and Specialties of the Head and Neck, vol. Apr;38 Suppl 1, E1075-E1085, 2016
2016 Lin YW, Lee LM, Lee WJ, Chu CY, Tan P, Yang YC, Chen WY, Yang SF, (Hsiao M, Chien MH, Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB-DNAbinding activity, Journal of Pineal Research, vol. Apr;60(3):277-290, 2016
2016 Hsu CY, Lin CH, Jan YH, Su CY, Yao YC, Cheng HC, Hsu TI, Wang PS, Su WP, Yang CJ, Huang MS, Calkins MJ, (Hsiao M)*, Lu PJ, Huntingtin-Interacting Protein-1 Is an Early-stage Prognostic Biomarker of Lung Adenocarcinoma and Suppresses Metastasis via Akt-mediated EMT., American Journal of Respiratory and Critical Care Medicine, vol. Apr 15;193(8):869-880, Cite 10, 2016
2016 Cheng PW, Lee HC, Lu PJ, Chen HH, lai CC, Sun GC, Yen TC, (Hsiao M, Lin YT, Liu CP, Tseng CJ, Resveratrol inhibition of Rac1-derived reactive oxygen species by AMPK decreases blood pressure in a fructose-induced rat model of hypertension, Scientific Reports, vol. May 3;6:25342, 2016
2016 Yeh SC, Wang PY, Lou YW, Khoo KH, (Hsiao M, Hsu TL, Wong CH, Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity., Proceedings of the National Academy of Sciences of the United States of America, vol. May 17;113(20), 5592-5597, 2016
2016 Su YH, Huang WC, Huang TH, Huang YJ, Sue YK, Huynh TT, (Hsiao M, Liu TZ, AT Wu, Lin CM, Folate deficient tumor microenvironment promotes epithelial-to-mesenchymal transition and cancer stem-like phenotypes., Oncotarget, vol. May 31;7(22):33246-33256, 2016
2016 Chang YC, Su CY, (Hsiao M)*, Therapeutic targeting of methylthioadenosine phosphorylase , Cancer Cell & Microenvironment, vol. June;3:e1322. (Invited Review), 2016
2016 Kosheleva OK, Lai TC, Chen NG, (Hsiao M)*, Chen CH*, Selective killing of cancer cells by nanoparticle-assisted ultrasound., Journal of Nanobiotechnology, vol. June 14;14(1):46, 2016
2016 Chan YC, Chen CW, Chan MH, Chang YC, Chang MW, Chi LH, Yu HM, Lin YF, Tsai DP, Liu RS, (Hsiao M)*, MMP2-sensing up-conversion nanoparticle for fluorescence biosensing in head and neck cancer cells, Biosensors & Bioelectronics, vol. Jun 15;80:131-139, Cite 17, 2016
2016 Lin CH, Tsai CH, Yeh CT, Liang JL, Hung WC, Lin FC, Chang WL, Li HY, Yao YC, Hsu TI, Lee YC, Wang YC, Sheu BS, Lai WW, Calkins MJ, (Hsiao M)*, Lu PJ, MiR-193a-5p/ERBB2 act as concurrent chemoradiation therapy response indicator of esophageal squamous cell carcinoma., Oncotarget, vol. June 28;7(26):39680-39693, 2016
2016 Peng HY, Jiang SS, Hsiao JR, (Hsiao M, Hsu YM, Wu GH, Chang WM, Chang JY, Jin SC, Shiah SG, IL-8 induces miR-424-5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinoma, Mol Oncol, vol. Jun;10(6), 895-909, 2016
2016 Yang YC, Cheng TY, Huang SM, Su CY, Yang PW, Lee JM, Chen CK, (Hsiao M, Hua KT, Kuo ML, Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR association., Oncogene, vol. Jun 30;35(26), 3387-98, 2016
2016 Lin CW, Yang WE, Lee WJ, Hua KT, Hsieh FK, (Hsiao M, Chen CC, Chow JM, Chen MK, Yang SF, Chien MH, Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with favourable prognosis., Carcinogenesis, vol. Jul;37(7), 712-722, 2016
2016 Su CY, Chang YC, Yang CJ, Huang MS, (Hsiao M)*, The opposite prognostic effect of NDUFS1 and NDUFS8 forms a prognostic panel for non-small cell lung cancer by reflecting the oncojanus role of mitochondrial complex I, Scientific Reports, vol. Aug 12;6, 31357, 2016
2016 Chen CK, Yu WH, Cheng TY, Chen MW, Su CY, Yang YC, Kuo TC, Lin MT, (Hsiao M, Hua KT, Hung MC, Kuo ML, Inhibition of VEGF165/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis, Scientific Reports, vol. Aug 10;6, 31398, 2016
2016 Lai CC, Cheng PW, Yeh TC, Lu PJ, (Hsiao M, Liu CP, Tseng CJ, Paricalcitol attenuates cardiac fibrosis and expression of endothelial cell transition markers in isoproterenol-induced cardiomyopathic rats, Critical Care Medicine, vol. 44(9), e866-e874, 2016
2016 Wei L, Su YK, Lin CM, Chao TY, Huynh TT, Jan HJ, Whang-Peng J, Chiou JF, Wu AT, (Hsiao M)*, Preclinical investigation of Ibrutinib, a Bruton’s kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes, Oncotarget, vol. Oct. 25;7(43), 69961-975, 2016
2016 Chan MH, Chen CW, Lee IJ, Chan YC, Tu DT, (Hsiao M)*, Chen CH, Chen XY, Liu RS, Near-infrared light-mediated photodynamic therapy nanoplatform by electrostatic assembly of NaYF4:Yb/Tm upconversion nanoparticles with graphitic carbon nitride quantum dots, Inorganic Chemistry, vol. 55(20), 10267-10277, 2016
2016 Chen CW, Chan YC, (Hsiao M)*, Liu RS, Plasmon-enhanced photodynamic cancer therapy by upconversion nanoparticles conjugated with Au nanorods, ACS Applied Materials & Interfaces, vol. 1, 1, 2016
2016 Lo YL, Liou GG, Lyu JH, (Hsiao M, Hsu TL, Wong CH*, Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex., PLoS One, vol. Nov 10;11(11), e0166474, 2016
2016 Chen HH, Cheng PW, Ho WY, Lu PJ, Lai CC, Tseng YM, Fang HC, Sun GC, (Hsiao M, Liu CP, Tseng CJ, Renal denervation improves the baroreflex and GABA system normalization in chronic kidney disease-associated hypertension, Scientific Reports, vol. 6, 38447, 2016
2016 Kuo TC, Chen CK, Hua KT, Yu P, Lee WJ, Chen MW, Jeng YM, Chien MH, Kuo KT, (Hsiao M, Kuo ML, Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells., Cancer Letters, vol. Dec 28;383(2), 282-294, 2016
2016 Chang WM, Lin YF, Su CY, Peng HY, Chang YC, Lai TC, Wu GH, Hsu YM, Chi LH, Hsiao JR, Chen CL, Chang JY, Shieh YS, (Hsiao M)*, Shiah SG, Dysregulation of Runx2/Activin A axis upon miR376c downregulation promotes lymph node metastasis in head and neck squamous cell carcinoma., Cancer Research, vol. 76(24),7140-7150, Cite 16, 2016
2016 L. Krasnova, Understanding the Chemistry and Biology of Glycosylation with Glycan Synthesis, Annual Review of Biochemistry, vol. 85, 599-630, 2016
2016 G. B. E. Stewart-Jones, C. Soto, T. Lemmin, G.-Y. Chuang, A. Druz, R. Kong, P. V. Thomas, K. Wagh, T. Zhou, A.-J. Behrens, T. Bylund, C. W. Choi, J. R. Davison, I. S. Georgiev, M. G. Joyce, Y. D. Kwon, M. Pancera, J. Taft, Y. Yang, B. Zhang, S. S. Shivatare, V. S. Shivatare, C.-C. D. Lee, C.-Y. Wu, C. A. Bewley, D. R. Burton, W. C. Koff, M. Connors, M. Crispin, B. T. Korber, J. R. Mascola, P. D. Kwong, Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G., Cell, vol. 165(4), 813-826, 2016
2016 C.-H. Hsu, S. Park, D. E. Mortenson, B. L. Foley, X. Wang, R. J. Woods, D. A. Case, E. T. Powers, H. J. Dyson, J. W. Kelly, The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate., Journal of the American Chemical Society, vol. 138(24), 7636-7648, 2016
2016 S. K. C. Cheung, P.-K. Chuang, H.-W. Huang, W. W. Hwang-Verslues, C. H.-H. Cho, W.-B. Yang, C.-N. Shen, M. Hsiao, T.-L. Hsu, C.-F. Chang, Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells., Proceedings of the National Academy of Sciences of the United States of America, vol. 113(4), 960-965, 2016
2016 T.-C. Kuo, L.-W. Li, S.-H. Pan, J.-M. Fang, J.-H. Liu, T.-R. Cheng, C.-J. Wang, P.-F. Hung, H.-Y. Chen, T.-M. Hong, Y.-L .Hsu, P.-C. Yan, Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin., JOURNAL OF MEDICINAL CHEMISTRY, vol. 59(18), 8521-8534, 2016
2016 T.-N. Wu, K.-H. Lin, Y.-T. Wu, J.-R. Huang, J.-T. Hung, J.-C. Wu, C.-Y. Chen, K.-C. Chu, N.-H. Lin, A. L.Yu, Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation., ACS chemical biology, vol. 11(12), 3431-3441, 2016
2016 P.-C. Wang, J.-M. Fang, K.-C. Tsai, S.-Y. Wang, W.-I. Huang, Y.-S. Cheng, R. C., Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors., Journal of medicinal chemistry, vol. 59(11), 5297-5310, 2016
2016 S. S. Shivatare, S.-H. Chang, T.-I. Tsai, S. Y. Tseng, Y.-S. Lin, Y.-Y. Cheng, C.-T. Ren, S. Pawar, C.-S. Tsai, H.-W. Shi, Y.-F. Zeng, C.-H. Liang, P. D. Kwong, D. R. Burton, C.-Y. Wu, Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies, Nature Chemistry, vol. 8(4), 338-346, 2016
2016 Y. Kizuka, S. Funayama, H. Shogomori, M. Nakano, K. Nakajima, R. Oka, S. Kitazume, Y. Yamaguchi, M. Sano, H. Korekane, T.-L. Hsu, H.-Y. Lee, N. Taniguchi, High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery., Cell Chemical Biology, vol. 23(7), 782-792, 2016
2016 S.-C. Yeh, P.-Y. Wang, Y.-W. Lou, K.-H. Khoo, M. Hsiao, T.-L. Hsu, Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity., Proceedings of the National Academy of Sciences of the United States of America, vol. 113(20), 5592-5597, 2016
2016 L. Krasnova, Exploring human glycosylation for better therapies., MOLECULAR ASPECTS OF MEDICINE, vol. S0098-2997, 2016
2016 D. T. MacLeod, N. M. Choi, B. Briney, F. Garces, L. S. Ver, E. Landais, B. Murrell, T. Wrin, W. Kilembe, C.-H. Liang, A. Ramos, C.-B. Bian, L. Wickramasinghe, L. Kong, K. Eren, C.-Y. Wu, S. L. Kosakovsky Pond, I. A. Wilson, D. R. Burton, P. Poignard, Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch., Immunity, vol. 44(5), 1215-1226, 2016
2016 Y.-L. Lo, G.-G. Liou, C.-H. Lu, M. Hsiao, T.-L. Hsu, Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex., PloS one, vol. 11(11), e0166474, 2016
2016 D. Sok, M. Pauthner, B. Briney, J.-H. Lee, K. L.Saye-Francisco, J. Hsueh, A. Ramos, K.-M. Le, M. Jones, J. G. Jardine, R. Bastidas, A. Sarkar, C.-H. Liang, S. S. Shivatare, C.-Y. Wu, W. R. Schief, I. A. Wilson, A. B. Ward, J. Zhu, P. Poignard, D. R. Burton, A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans., Immunity, vol. 45(1), 31-45, 2016
2016 S. Y. Tseng, W.-H. Cho, J. Su, S.-H. Chang, D. Chiang, C.-Y. Wu, C.-N. Hsiao, Preparation of Aluminum Oxide-Coated Glass Slides for Glycan Microarrays, ACS Omega, vol. 1(5), 773–783, 2016
2016 Sheng-Hung Wang, Andy Chi-Lung Lee, I-Ju Chen, Nai-Chuan Chang, Han-Chung Wu, Hui Ming Yu, Ya-Jen Chang, Te-Wei Lee, Jyh-Cherng Yu, Alice Yu, John Yu, Structure-Based Optimization of GRP78-Binding Peptides that Enhances Efficacy in Cancer Imaging and Therapy, Biomaterials, vol. 94, 31-44, 2016
2016 Kizuka Yasuhiko, Funayama Sho, Shogomori Hidehiko, Nakano Miyako, Nakajima Kazuki, Oka Ritsuko, Kitazume Shinobu, Yamaguchi Yoshiki, Sano Masahiro, Korekane Hiroaki, Hsu Tsui-Ling, Lee Hsiu-Yu, Wong Chi-Huey, Taniguchi Naoyuki, High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery, Cell Chemical Biology, vol. 23(7), 782-792, 2016
2016 Yeh Shih-Chi, Wang Pao-Yuan, Lou Yi-Wei, Khoo Kay-Hooi, Hsiao Michael, Hsu Tsui-Ling, Wong Chi-Huey, Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity, Proceedings of the National Academy of Sciences, vol. 113(20), 5592-5597, 2016
2016 Lo Yen-Lung, Liou Gunn-Guang, Lyu Jia-Huei, Hsiao Michael, Hsu Tsui-Ling, Wong Chi-Huey, Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex, PLOS ONE, vol. 11(11), e0166474, 2016
2016 Teng Ooiean, Chen Szu-Ting, Hsu Tsui-Ling, Sia Sin Fun, Cole Suzanne, Valkenburg Sophie A., Hsu Tzu-Yun, Zheng Jian Teddy, Tu Wenwei, Bruzzone Roberto, Peiris Joseph Sriyal Malik, Hsieh Shie-Liang, Yen Hui-Ling, CLEC5A-Mediated Enhancement of the Inflammatory Response in Myeloid Cells Contributes to Influenza Virus PathogenicityIn Vivo, Journal of Virology, vol. 91(1), e01813-16, 2016
2016 Tsai Tsung-I, Li Shiou-Ting, Liu Chiu-Ping, Chen Karen Y., Shivatare Sachin S., Lin Chin-Wei, Liao Shih-Fen, Lin Chih-Wei, Hsu Tsui-Ling, Wu Ying-Ta, Tsai Ming-Hung, Lai Meng-Yu, Lin Nan-Horng, Wu Chung-Yi, Wong Chi-Huey, An Effective Bacterial Fucosidase for Glycoprotein Remodeling, ACS Chemical Biology, vol. 12(1), 63-72, 2016
2016 Chen KT, Chen PT, Lin CK, Huang LY, Hu CM, Chang YF, Hsu HT, Cheng TJ, Wu YT, Cheng WC, Structural Investigation of Park
2016 Kuo TC, Li LW, Pan SH, * Fang JM, * Liu JH, (Cheng TJ, Wang CJ, Hung PF, Chen HY, Hong TM, Hsu YL, Wong CH, Yang PC, Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin., Journal of medicinal chemistry, vol. 59(18), 8521-34, 2016
2016 Wang PC, Fang JM, * Tsai KC, Wang SY, Huang WI, Tseng YC, Cheng YS, (Cheng TJ, Wong CH, Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors., Journal of medicinal chemistry, vol. 59, 5297-5310, 2016
2016 Huang YP, Cho CC, (Chang CF)*, Hsu CH*, NMR assignments of the macro domain from Middle East respiratory syndrome coronavirus (MERS-CoV)., Biomolecular NMR assignments, vol. 10(2), 245-248, 2016
2016 Liang CT, Huang HB, Wang CC, Chen YR, (Chang CF, Shiao MS, Chen YC, Lin TH, L17A/F19A Substitutions Augment the alpha-Helicity of beta-Amyloid Peptide Discordant Segment., PloS one, vol. 11(4), e0154327, 2016
2016 Chou CY, Chu M, (Chang CF, Yu T, Huang TH, Sakellariou D, High sensitivity high-resolution full range relaxometry using a fast mechanical sample shuttling device and a cryo-probe., Journal of biomolecular NMR, vol. 66(3), 187-194, 2016
2016 Hu HH, Liu J, Lin YL, Luo WS, Chu YJ, Chang CL, Jen CL, Lee MH, Lu SN, Wang LY, You SL, (Yang HI*, Chen CJ, The rs2296651 (S267F) variant on NTCP (SLC10A1) is inversely associated with chronic hepatitis B and progression to cirrhosis and hepatocellular carcinoma in patients with chronic hepatitis B., Gut, vol. 65, 1514-1521, 2016
2016 Liu J, (Yang HI, Lee MH, Jen CL, Batrla-Utermann R, Lu SN, Wang LY, You SL, Chen CJ, Serum Levels of Hepatitis B Surface Antigen and DNA Can Predict Inactive Carriers With Low Risk of Disease Progression., HEPATOLOGY, vol. 64(2), 381-389, 2016
2016 Chien J, Liu J, Lee MH, Jen CL, Batrla-Utermann R, Lu SN, Wang LY, You SL, (Yang HI, Chen CJ, Risk and Predictors of Hepatocellular Carcinoma for Chronic Hepatitis b Patients With Newly Developed Cirrhosis., Journal of gastroenterology and hepatology, vol. 31(12), 1971-1977, 2016
2016 Lin D, (Yang HI*, Nguyen N, Hoang J, Kim Y, Vu V, Le A, Chaung K, Nguyen V, Trinh H, Li J, Zhang J, Hsing A, Chen CJ, Nguyen MH*, Reduction of chronic hepatitis B-related hepatocellular carcinoma with anti-viral therapy, including low risk patients., Alimentary pharmacology & therapeutics, vol. 44(8), 846-855, 2016
2016 Poh Z, Shen L, (Yang HI, Seto WK, Wong VW, Lin CY, Goh BG, Chang PJ, Chan HL, Yuen MF, Chen CJ, Tan CK, Real-world risk score for hepatocellular carcinoma (RWS-HCC): a clinically practical risk predictor for HCC in chronic hepatitis B., Gut, vol. 65(5), 887-888, 2016
2016 Chen YC*, Hsiao CJ, Jung CC, Hu HH, Chen JH, Lee WC, Chiou JM, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, Chen CJ*, (Yang HI*, Performance Metrics for Selecting Single Nucleotide Polymorphisms in Late-onset Alzheimer's Disease., Scientific Reports, vol. 6, 36155, 2016
2016 Huang YT, Freeman JR, (Yang HI, Liu J, Lee MH, Chen CJ, Mediation effect of hepatitis B and C on mortality., European journal of epidemiology, vol. 31(6), 625-633, 2016
2016 Hoang JK, (Yang HI*, Le A, Nguyen NH, Lin D, Vu VD, Chaung K, Nguyen V, Trinh HN, Li J, Zhang JQ, Chen CJ, Nguyen MH*, Lower liver cancer risk with antiviral therapy in chronic hepatitis B patients with normal to minimally elevated ALT and no cirrhosis., Medicine, vol. 95(31), e4433, 2016
2016 Yang HI, Tseng TC, Liu J, Lee MH, Liu CJ, Su TH, Batrla-Utermann R, Chan HL, Kao JH, Chen CJ, Incorporating Serum Level of Hepatitis B Surface Antigen or Omitting Level of HBV DNA Does not Affect Calculation of Risk for Hepatocellular Carcinoma in Patients Without Cirrhosis, CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, vol. 14(3), 461-468, 2016
2016 Lin YJ, Shaw TG, (Yang HI, Lu SN, Jen CL, Wang LY, Wong KH, Chan SY, Yuan Y, L'Italien G, Chen CJ, Lee MH, Chronic hepatitis C virus infection and the risk for diabetes: a community-based prospective study., Liver international : official journal of the International Association for the Study of the Liver, vol. doi: 10.1111/liv.13194, 2016
2016 Wu HC, Shen J, (Yang HI, Tsai WY, Chen CJ, Santella RM, Blood DNA methylation markers in prospectively identified hepatocellular carcinoma cases and controls from Taiwan., World journal of hepatology, vol. 8(5), 301-306, 2016
2016 Liu J, (Yang HI, Lee MH, Jen CL, Hu HH, Lu SN, Wang LY, You SL, Huang YT, Chen CJ, Alcohol drinking mediates the association between polymorphisms of ADH1B and ALDH2 and hepatitis B related hepatocellular carcinoma., Cancer Epidemiology Biomarkers & Prevention, vol. 25(4), 693-699, 2016
2016 Y.-H. Lai, Y.-H. Cai, H. Lee, Y.-M. Ou, C.-H. Hsiao, C.-W. Tsao, H.-T. Chang, Y.-S. Wang*, Reducing spatial heterogeneity of MALDI samples with Marangoni flows during sample preparation, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, vol. 27(8), 1314-1321, 2016
2016 Chang, K.-K.; Cai, Y.-H.; Chen, C.-H.; Wang, Y.-S.;*, Neutralization charge detection method for detecting ions under ambient and liquid phases., CHEMICAL COMMUNICATIONS, vol. 52(29), 5187-5189, 2016
2016 Dutkiewicz E. P., Hsieh K.-T., Wang Y.-S., Chiu H.-Y., Urban P. L., Hydrogel Micropatch and Mass Spectrometry-Assisted Screening for Psoriasis-Related Skin Metabolites, Clinical Chemistry, vol. 62(8), 1120-1128, 2016
2016 Primadona Indah, Lai Yin-Hung, Capangpangan Rey Y., Obena Rofeamor P., Tseng Mei-Chun, Huang Ming-Feng, Chang Huan-Tsung, Li Shiou-Ting, Wu Chung-Yi, Chien Wei-Ting, Lin Chun-Cheng, Wang Yi-Sheng, * Chen Yu-Ju*, Functionalized HgTe nanoparticles promote laser-induced solid phase ionization/dissociation for comprehensive glycan sequencing, The Analyst, vol. 141(21), 6093-6103, 2016
2016 Y.-M. Ou, C.-W. Tsao, Y.-H. Lai, H. Lee, H.-T. Chang, Y.-S. Wang*, Preparation of homogeneous MALDI samples for quantitative applications, JOVE-Journal of Visualized experiments, vol. 116, e54409, 2016
2016 C.-C. Wang, Y.-H. Lai, Y.-M. Ou, H.-T. Chang, Y.-S. Wang*, Critical Factors Determining Quantification Capability of MALDI-TOF Mass Spectrometry, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, vol. 374(2079), 20150371, 2016
2016 Cheung SK, Chuang PK, Huang HW, Hwang-Verslues WW, Cho CH, Yang WB, (Shen CN, Hsiao M, Hsu TL, Chang CF, Wong CH, Stage-specific embryonic antigen-3 (SSEA-3) and beta3GalT5 are cancer specific and significant markers for breast cancer stem cells., Proceedings of the National Academy of Sciences of the United States of America, vol. 113(4), 960-965, 2016
2016 Chang HM, Huang WY, Lin SJ, Huang WC, Shen CR, Mao WY, (Shen CN*, ABCG2 deficiency in skin impairs re-epithelialization in cutaneous wound healing., Experimental dermatology, vol. 25(5), 355-361, 2016
2016 Lien HW, Yuan RY, Chou CM, Chen YC, Hung CC, Hu CH, Hwang SP, Hwang PP, (Shen CN, Chen CL, Cheng CH, Huang CJ, Zebrafish cyclin Dx is required for development of motor neuron progenitors, and its expression is regulated by hypoxia-inducible factor 2alpha., Scientific reports, vol. 6, 28297, 2016
2016 Chien, C.Y., H.S. Lee*, Candy.H.H. Cho, K.I. Lin, D. Tosh, R.R. Wu, W.Y. Mao, (C.N. Shen*, Maternal Vitamin A deficiency during pregnancy affects vascularized islet development, Journal of Nutritional Biochemistry, vol. 36, 51-59, 2016
2016 Lin PY, Peng SJ, (Shen CN*, Pasricha PJ, Tang SC, PanIN-associated pericyte, glial, and islet remodeling in mice revealed by 3-D pancreatic duct lesion histology., American Journal of Physiology-Gastrointestinal and Liver Physiology, vol. 311(3), G412-G422, 2016
2016 Liu CM, Hsieh CL, (Shen CN, Lin CC, Shigemura K, Sung SY, Exosomes from the tumor microenvironment as reciprocal regulators that enhance prostate cancer progression., International journal of urology, vol. 23(9), 734-744, 2016
2016 Chien, C.Y., T.A. Yuan, Candy.H.H. Cho, F.P. Chang, W.Y. Mao, R.R. Wu, H.S. Lee*, (C.N. Shen*, All-trans retinoic acid ameliorates glycemic control in diabetic mice via modulating pancreatic islet production of vascular endothelial growth factor-A, Biochemical and Biophysical Research Communications, vol. 477(4), 874-880., 2016
2016 F.P. Chang, C.H. Cho, C.R. Shen, C.Y. Chien, L.W.Ting, H.S. Lee, (C.N. Shen*, PDGF Facilitates Direct Lineage Reprogramming of Hepatocytes to Functional ß-Like Cells Induced by Pdx1 and Ngn3, Cell transplantation, vol. 25(10), 1893-1909, 2016
2016 Chen CP, Lin MH, Chan YT, Chen LC, Ma C*, Fischer WB*, Membrane protein assembly: two cytoplasmic phosphorylated serine sites of Vpu from HIV-1 affect oligomerization., Scientific reports, vol. 6, 28866, 2016
2016 Lee CP, Chiang SL, Ko AM, Liu YF, Ma C, Lu CY, Huang CM, Chang JG, Kuo TM, Chen CL, Tsai EM, Ko YC, ALPK1 phosphorylates myosin IIA modulating TNF-alpha trafficking in gout flares., Scientific reports, vol. 6, 25740, 2016
2016 Huang YC, Lin SJ, Lin KM, Chou YC, Lin CW, Yu SC, Chen CL, Shen TL, Chen CK, Lu J, Chen MR, Tsai CH, Regulation of EBV LMP1-triggered EphA4 downregulation in EBV-associated B lymphoma and its impact on patients