具代表性研究發表

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年度 論文名稱
2018 Pang SEE-TONG, Chang Ying-Hsu, Lin Po-Hung, Chang Ying, Watson Drew, Segurado Oscar, Lu Si-Hong, Wu Jen-chia, Lai Jr-Ming, Shao Hung-Jen, Chang Shih-En, Hsieh Ben, Javey Mana, Mei Rui, Prospective clinical study of a prostate cancer (PCa) rule-out blood test for PSA gray zone patients using a sensitive circulating tumor cell assay., Journal of Clinical Oncology, vol. 36(6_suppl), 143-143, 2018
2018 Yang Chih-Tsung, Wu Jen-Chia, Chang Ying-Chih, Facile Synthesis of High Molecular Weight Polypeptides via Surface-Initiated Vapor Deposition Polymerization, Polymer Preprints, vol. Version 1, 2018
2018 Lee I-Ming, Yang Feng-Ling, Chen Te-Li, Liao Kuo-Shiang, (Ren Chien-Tai, Lin Nien-Tsung, Chang Yu-Pei, Wu Chung-Yi*, Wu Shih-Hsiung*, Pseudaminic acid on exopolysaccharide of Acinetobacter baumannii plays a critical role in phage-assisted preparation of glycoconjugate vaccine with high antigenicity, Journal of the American Chemical Society, vol. 140(28), 8639-8643, 2018
2018 Tsai HW, Huang MT, Wang PH, Huang BS, Chen YJ, (Hsieh SL)*., Decoy receptor 3 promotes cell adhesion and enhances endometriosis development, JOURNAL OF PATHOLOGY, vol. 244(2), 189-202, 2018
2018 Tsai TY, Peng CY, Yang HI, Huang YL, Tao MH, Yuan SS, Lai HC, (Hsieh SL)*, The human C-type lectin 18 is a potential biomarker in patients with chronic hepatitis B virus infection, JOURNAL OF BIOMEDICAL SCIENCE, vol. 25(1): 59, 1-10, 2018
2018 Liao TL, Huang YL, Chen YM, Lee HC, Chen DY, (Hsieh SL*, Association of C-type lectin 18 levels with extrahepatic manifestations in chronic HCV infection, SCIENTIFIC REPORTS, vol. 8(1): 17287, 1-11, 2018
2018 Chan MH, Chen SP, Chen CW, Chan YC, Lin RJ, Tsai DP, (Hsiao M)*, Chung RJ, Chen X, Liu RS, Single 808 nm laser treatment comprising photothermal and photodynamic therapies by using gold nanorod hybrid upconversion particles, Journal of Physical Chemistry C, vol. 122(4), 2402-2412, 2018
2018 Chan YC, Chan MH, Chen C, Liu RS, (Hsiao M)*, Tsai DP, Near-Infrared-Activated Fluorescence Resonance Energy Transfer-Based Nanocomposite to Sense MMP2-Overexpressing Oral Cancer Cells, ACS Omega, vol. 3(2), 1627-1634, 2018
2018 Chan MH, Pan YT, Chan YC, (Hsiao M)*, Chen CH, Sun L, Liu RS, Nanobubble-embedded inorganic 808 nm excited-upconversion nanocomposites for tumorous multiple imaging and treatment, Chemical Science, vol. Feb 9; 9(12), 3141-3151, 2018
2018 Wu CH, Lan CH, Wu KL, Wu YM, Jane WN, (Hsiao M, Wu HC, Hepatocellular carcinoma-targeted nanoparticles for cancer therapy, International Journal of Oncology, vol. 52(2), 389-401, 2018
2018 Cheng TY, Yang YC, Wang HP, Tien YW, Shun CT, Huang HY, (Hsiao M, Hua KT, Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 protein., Oncogene, vol. 37(13), 1730-1742, 2018
2018 Lin TC, Huang KW, Liu CW, Chang YC, Lin WM, Yang TY, (Hsiao M)*, Leptin signaling axis associates with clinical prognosis and is multifunctional in regulating cancer progression, Oncotarget, vol. 9(24), 17210-17219, 2018
2018 Liu M, Bamodu OA, Kuo KT, Lee WH, Lin YK, Wu ATH, (M Hsiao, Tzeng YM, Yeh CT, Tsai JT, Downregulation of cancer stemness by novel diterpenoid ovatodiolide inhibits hepatic cancer stem cell-like traits by repressing wnt/b-catenin signaling, American Journal of Chinese Medicine, vol. 46(4), 891-910, 2018
2018 Yang YC, Chien MH, Liu HY, Chang YC, Chen CK, Lee WJ, Kuo TC, (Hsiao M, Hua KT, Cheng TY, Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stress., Cancer Letters, vol. May 1;421, 28-40, 2018
2018 Huang SP, Chiou J, Jan YH, Lai TC, Yu YL, (Hsiao M)*, Lin YF, Over-expression of lysyl oxidase is associated with poor prognosis and response to therapy of patients with lower grade gliomas, Biochemical and Biophysical Research Communications, vol. 501(3), 619, 627, 2018
2018 Chang YC, Yang YC, Tien CP, Yang CJ, (Hsiao M)*, Roles of aldolase family genes in human cancers and diseases - [Invited Review], Trends in Endocrinology and Metabolism, vol. Aug;29(8), 549-559, 2018
2018 Kuo KT; Huang WC, Bamodu OA, Lee WH, Wang CH, (Hsiao M, Wang LS, Yeh CT, Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor, Clinical Epigentics, vol. Aug 9;10(1), 107, 2018
2018 Chang JH, Cheng CW, Yang YC, Chen WS, Hung WY, Chow JM, Chen PS, (Hsiao M, Lee WJ, Chien MH, Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses., Journal of Experimental & Clinical Cancer Research, vol. 37(1), 199, 2018
2018 Wang PS, Chou CH, Lin CH, Yao YC, Cheng HC, Li HY, Ger LP, Chen YC, Lin FC, (Hsiao M)*, Lu PJ, A novel long non-coding RNA linc-ZNF469-3 promotes lung metastasis through miR-574-5p-ZEB1 axis in triple negative breast cancer, Oncogene, vol. 37(34), 4662-4678, Cite 14, 2018
2018 Bamodu OA, Yang CK, Tzeng DT, Kuo KT, Huang CC, Deng L, (Hsiao M, Lee WH, Yeh CT, 4-Acetyl-antroquinonol B suppresses SOD2-enhanced cancer stem cell-like phenotypes and chemoresistance of colorectal cancer cells by inducing hsa-miR-324 re-expression, Cancers, vol. 10(8), 269, 2018
2018 Wu SY, Huang YJ, Tseng YM, Huang CY, (Hsiao M, Wu AT, Huang TH, Destruxin B suppresses drug-resistant colon tumorigenesis and stemness is associated with the upregulation of miR-214 and downregulation of mTOR/β-catenin pathway, Cancers, vol. 10(10), 353, 2018
2018 Chien MH, Lee WJ, Yang YC, Tan P, Pan KF, Liu YC, Tsai HC, Hsu CH, Wen YC, (Hsiao M, Hua KT, N-α-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas, Cancer Letters, vol. 433, 86-98, 2018
2018 Chuang HH, Huang MS, Wang PH, Liu YP, (Hsiao M, Yang CJ, Pin1 Is involved in HDAC6-mediated cancer cell motility, International Journal of Medical Sciences, vol. 15(13), 1573-1581, 2018
2018 Hung WY, Chang JH, Cheng Y, Chen CK, Chen JQ, Hua KT, Cheng CW, (Hsiao M, Chung CL, Lee WJ, Chien MH, Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung Cancer Progression Through Antagonizing MET and EGFR Activities., Cellular Physiology and Biochemistry, vol. 51(1), 337-355, 2018
2018 Shu CW, Tzeng YD, Li JY, Liu PF, Kuo SY, Liu LF, Hsieh CW, Lee CH, Wu CH, (Hsiao M, Chang HT, Kinome-wide siRNA screening identifies Src-enhanced resistance of chemotherapeutic drugs in triple-negative breast cancer cells, Frontiers in Pharmacology, vol. Nov 9;9:1285, 2018
2018 Kuo WY, Hsu HJ, Wu CY, Chen HS, Chou YC, Tsou YL, Peng HP, Jian JW, Yu CM, Chiu YK, Chen IC, Tung CP, (Hsiao M, Lin CL, Wang YA, Wang AH, Yang AS, Antibody-drug conjugates with HER2-targeting antibodies from synthetic antibody libraries are highly potent against HER2-positive human gastric tumor in xenograft models., mAbs, vol. 11(1),153-165, 2018
2018 Liu HW, Su YK, Bamodu OA, Hueng DY, Lee WH, Huang CC, Deng L, (Hsiao M, Chien MH, Yeh CT, Lin CM, The disruption of the β-catenin/TCF-1/Stat3 signaling axis by 4-Acetylantroquinonol B inhibits the tumorigenesis and cancer stem cell-like properties of glioblastoma cells, in vitro and in vivo, Cancers, vol. 10(12), 491, 2018
2018 V. S. Shivatare, S. S. Shivatare, C.-C. Lee, C.-H. Liang, K.-S. Liao, Y.-Y. Cheng, G. Saidachary, C.-Y. Wu, N.-H. Lin, P. D. Kwong, D. Burton, C.-Y. Wu, Unprecedented Role of Hybrid N-Glycans as Ligands for HIV-1 Broadly Neutralizing Antibodies., Journal of the American Chemical Society, vol. 140(15), 5202-5210, 2018
2018 X. Wang, L. Krasnova, K. B. Wu, W.-S. Wu, T.-J. Cheng, Towards new antibiotics targeting bacterial transglycosylase: Synthesis of a Lipid II analog as stable transition-state mimic inhibitor., Bioorganic & Medicinal Chemistry Letters, vol. 28(16 SI), 2708-2712, 2018
2018 S. Dey, S. O. Bajaj, T.-I. Tsai, H.-J. Lo, K. Wu, Synthesis of Modular Building Blocks using Glycosyl Phosphate Donors for the Construction of Asymmetric N-Glycans, TETRAHEDRON, vol. 74(41), 6003-6011, 2018
2018 S. Dey, Programmable one-pot synthesis of heparin pentasaccharides enabling access to regiodefined sulfate derivatives, Chemical Science, vol. 9(32), 6685-6691, 2018
2018 P.-W. Lo, J.-J. Shie, C.-H. Chen, C.-Y. Wu, T.-L. Hsu, O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2, Proceedings of the National Academy of Sciences of the United States of America, vol. 115(28), 7302-7307, 2018
2018 C.-W. Cheng, Y. Zhou, W.-H. Pan, S. Dey, C.-Y. Wu, W.-L. Hsu, Hierarchical and programmable one-pot automated synthesis of oligosaccharides, Nature Communications, vol. 9, 5202, 2018
2018 C.-P. Liu, T.-I Tsai, T. Cheng, V. S. Shivatare, C.-Y. Wu, C.-Y. Wu, Glycoengineering of antibody (Herceptin) through yeast expression and in vitro enzymatic glycosylation., Proceedings of the National Academy of Sciences of the United States of America, vol. 115(4), 720-725, 2018
2018 C.-F. Huang, K. S. Liang, T.-L. Hsu, T.-T. Lee, Y.-Y. Chen, S.-M. Yang, H.-H. Chen, S.-H. Huang, W.-H. Chang, T.-K. Lee, P. Chen, K.-E. Peng, C.-C. Chen, C.-Z. Shi, Y.-F. Hu, G. Margaritondo, T. Ishikawa, Y. Hwu, Free-electron-laser coherent diffraction images of individual drug-carrying liposome particles in solution., Nanoscale, vol. 10(6), 2820-2824, 2018
2018 S. S. Shivatare, L.-Y. Huang, Y.-F. Zeng, J.-Y. Liao, T.-H. You, S.-Y. Wang, T. Cheng, C.-W. Chiu, P. Chao, L.-T. Chen, T.-I. Tsai, C.-C. Huang, C.-Y. Wu, N.-H. Lin, Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies, CHEMICAL COMMUNICATIONS, vol. 54(48), 6161-6164, 2018
2018 S. S. Shivatare, V. S. Shivatare, C.-Y. Wu, Chemo-Enzymatic Synthesis of N-Glycans for Array Development and HIV Antibodies Profiling, Jove-Journal of Visualized Experiments, vol. 132, 2018
2018 W.-S. Wu, W.-C. Cheng, T.-R. Cheng, Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase., Journal of the American Chemical Society, vol. 140(8), 2752-2755, 2018
2018 T. Zhou, A. Zheng, U. Baxa, G.-Y. Chuang, I. S. Georgiev, R. Kong, S. O’Dell, S. Shahzad-ul-Hussan, C.-H. Shen, Y. Tsybovsky, R. T. Bailer, S. K. Gift, M. K. Louder, K. McKee, R. Rawi, C. H. Stevenson, G. B. E. Stewart-Jones, J. D. Taft, E. Waltari, Y. Yang, B. Zhang, S. S. Shivatare, V. S. Shivatare, C.-C. D. Lee, C.-Y. Wu, NISC Comparative Sequencing Program, J. C. Mullikin, C. A. Bewley, D. R. Burton, V. R. Polonis, L. Shapiro, J. R. Mascola, P. D. Kwong, X. Wu, A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope., Immunity, vol. 48(3), 500-513.e6, 2018
2018 H.-W. Cheng, R.-J. Chein, T.-J. Cheng, P.-S. Wu, H.-Y. Wu, P.-F. Hung, C.-J. Wang, Y.-L. Hsu, J.-M. Wong, A. Yuan, P.-C. Yang, S.-H. Pan, 2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction., Cancer science, vol. 109(3), 832-842, 2018
2018 Huang Chi-Feng, Liang Keng S., Hsu Tsui-Ling, Lee Tsung-Tse, Chen Yi-Yun, Yang Shun-Min, Chen Hsiang-Hsin, Huang Shih-Hsin, Chang Wei-Hau, Lee Ting-Kuo, Chen Peilin, Peng Kuei-En, Chen Chien-Chun, Shi Cheng-Zhi, Hu Yu-Fang, Margaritondo Giorgio, Ishikawa Tetsuya, Wong Chi-Huey, Hwu Y., Free-electron-laser coherent diffraction images of individual drug-carrying liposome particles in solution, Nanoscale, vol. 10(6), 2820-2824, 2018
2018 Lo PW, Shie JJ, Chen CH, Wu CY, Hsu TL, Wong CH, O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2., Proceedings of the National Academy of Sciences of the United States of America, vol. 115(28), 7302-7307, 2018
2018 Wang PC, Chiu DC, Jan JT, Huang WI, Tseng YC, Li TT, (Cheng TJ, Tsai KC, Fang JM*, Peramivir conjugates as orally available agents against influenza H275Y mutant., European journal of medicinal chemistry, vol. 145, 224-234, 2018
2018 Huang SF, Lin CH, Lai YT, Tsai CL, (Cheng TR, Wang SK*, Development of Pseudomonas aeruginosa Lectin LecA Inhibitor by using Bivalent Galactosides Supported on Polyproline Peptide Scaffolds., Chemistry, an Asian journal, vol. 13(6), 686-700, 2018
2018 Wu WS, Cheng WC, (Cheng TR, * Wong CH*, Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase., Journal of the American Chemical Society, vol. 140, 2752-2755, 2018
2018 Hsu PH, Chiu DC, Wu KL, Lee PS, Jan JT, Cheng YE, Tsai KC, (Cheng TR, Fang JM*, Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses., European journal of medicinal chemistry, vol. 154, 314-323, 2018
2018 Cheng HW, Chein RJ, (Cheng TJ, Wu PS, Wu HY, Hung PF, Wang CJ, Hsu YL, Wong JM, Yuan A, Wong CH, Yang PC, Pan SH*, 2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction., Cancer science, vol. 109(3), 832-842, 2018
2018 Wang X, Krasnova L, Wu KB, Wu WS, (Cheng TR, Wong CH*, Towards new antibiotics targeting bacterial transglycosylase: Synthesis of a Lipid II analog as stable transition-state mimic inhibitor., Bioorganic & medicinal chemistry letters, vol. 28(16), 2708-2712, 2018
2018 Li TL, Hsu NS, Wang YL, Lin KH, (Chang CF, Lyu SY, Hsu LJ, Liu YC, Chang CY, Wu CJ, The Mesomeric Effect of Thiazolium on non-Kekule Diradicals in Pichia stipitis Transketolase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 57(7), 1802-1807, 2018
2018 Hsu Chen, Wu Bo-Yuan, Chang Yu-Chuan, (Chang Chi-Fon, Chiou Tai-Ying, Su Nan-Wei, Phosphorylation of Isoflavones by Bacillus subtilis BCRC 80517 May Represent Xenobiotic Metabolism, Journal of Agricultural and Food Chemistry, vol. 66(1), 127-137, 2018
2018 Mariasina SS, Petrova OA, Osterman IA, Sergeeva OV, Efimov SV, Klochkov VV, Sergiev PV, Dontsova OA, Huang TH, (Chang CF)*, Polshakov VI*, NMR assignments of the WBSCR27 protein related to Williams-Beuren syndrome., Biomolecular NMR assignments, vol. 12(2), 303-308, 2018
2018 Liang CT, Lin YS, Huang YC, Huang HL, Yang JQ, Wu TH, (Chang CF, Huang SJ, Huang HB, Lin TH, Characterization of the interactions between inhibitor-1 and recombinant PP1 by NMR spectroscopy., Scientific reports, vol. 8(1), 50, 2018
2018 Hsu NS, Wang YL, Lin KH, (Chang CF, Ke SC, Lyu SY, Hsu LJ, Li YS, Chen SC, Wang KC, Li TL, Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions., Chembiochem : a European journal of chemical biology, vol. 19(22), 2395-2402, 2018
2018 Polaris Observatory Collaborators, Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study., The Lancet Gastroenterology & Hepatology, vol. 3(6), 383-403, 2018
2018 O'Brien TR, (Yang HI, Groover S, Jeng WJ, Genetic Factors That Affect Spontaneous Clearance of Hepatitis C or B Virus, Response to Treatment, and Disease Progression., Gastroenterology, vol. 156(2)(SI), 400-417, 2018
2018 Chu YJ, (Yang HI, Wu HC, Lee MH, Liu J, Wang LY, Lu SN, Jen CL, You SL, Santella RM, Chen CJ, Aflatoxin B1 exposure increases the risk of hepatocellular carcinoma associated with hepatitis C virus infection or alcohol consumption., EUROPEAN JOURNAL OF CANCER, vol. 94, 37-46, 2018
2018 Shih S, Huang YT, (Yang HI, A multiple mediator analysis approach to quantify the effects of the ADH1B and ALDH2 genes on hepatocellular carcinoma risk., Genetic epidemiology, vol. 42(2), 394-404, 2018
2018 Lin YJ, Chang CL, Chen LC, Hu HH, Liu J, Korenaga M, Huang YH, Jen CL, Su CY, Nishida N, Sugiyama M, Lu SN, Wang LY, Yuan Y, L'Italien G, (Yang HI, Mizokami M, Chen CJ, Lee MH, A Glycomarker for Short-term Prediction of Hepatocellular Carcinoma: A Longitudinal Study With Serial Measurements., Clinical and translational gastroenterology, vol. 9(9), 183, 2018
2018 Tsai TY, Peng CY, (Yang HI, Huang YL, Tao MH, Yuan SS, Lai HC, Hsieh SL, The human C-type lectin 18 is a potential biomarker in patients with chronic hepatitis B virus infection., Journal of biomedical science, vol. 25,59, 2018
2018 Cai Yi-Hong, Wang Yi-Sheng*, Impact of uneven sample morphology on mass resolving power in linear MALDI-TOF mass spectrometry: A comprehensive theoretical investigation, Journal of Mass Spectrometry, vol. 53(4), 361-368, 2018
2018 Wei Shih-Chun, Fan Shen, Lien Chia-Wen, Unnikrishnan Binesh, Wang Yi-Sheng, Chu Han-Wei, Huang Chih-Ching, Hsu Pang-Hung, Chang Huan-Tsung*, Graphene oxide membrane as an efficient extraction and ionization substrate for spray-mass spectrometric analysis of malachite green and its metabolite in fish samples, Analytica Chimica Acta, vol. 1003, 42-48, 2018
2018 Ou Yu-Meng, Kuo Shu-Yun, Lee Hsun, Chang Huan-Tsung, Wang Yi-Sheng*, An Efficient Sample Preparation Method to Enhance Carbohydrate Ion Signals in Matrix-assisted Laser Desorption/Ionization Mass Spectrometry, Jove-Journal of Visualized Experiments, vol. 137, e57660, 2018
2018 S.C.Tang, (C.N. Shen*, P.Y. Lin, S.J. Peng, H.J. Chien, Y.H. Chou, C.E. Chamberlain, P.J. Pasricha., Pancreatic neuro-insular network in young mice revealed by 3D panoramic histology., Diabetologia, vol. 61(10), 158-167, 2018
2018 S.C.Tang, L. Baeyens, (C.N. Shen, S.J. Peng, H.J. Chien, D.W. Scheel, C.E. Chamberlain, M.S.German., Human pancreatic neuro-insular network in health and fatty infiltration., Diabetologia, vol. 61(1), 168-181, 2018
2018 T.L. Chen, Y.W. Lin, Y.B. Chen, J.J. Lin, T.L. Su, (C.N. Shen*, T.C. Lee*, A low-toxicity DNA-alkylating N-mustard-quinoline conjugate with preferential sequence specificity exerts potent antitumor activity against colorectal cancer, Neoplasia, vol. 20(2), 119-130, 2018
2018 Chuang, T.J., Chen, Y.J., Chen, C.Y., Mai, T.L., Wang, Y.D., Yeh, C.S., Yang, M.Y., Hsiao, Y.T., Chang, T.H., Kuo, H.C., Cho, H.H., (Shen, C.N., ) Kuo, H.C., Lu, M.Y., Chen, Y.H., Hsieh, S.C, Chiang, T.W., Integrative transcriptome sequencing reveals extensive alternative trans-splicing and cis-backsplicing in human cells, Nucleic Acids Research, vol. 46(7), 3671-3691, 2018
2018 Huang KA, Rijal P, Jiang H, Wang B, Schimanski L, Dong T, Liu YM, Chang P, Iqbal M, Wang MC, Chen Z, Song R, Huang CC, Yang JH, Qi J, Lin TY, Li A, Powell TJ, Jan JT, Ma C, Gao GF, Shi Y, Townsend AR, Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans., Nature microbiology, vol. 4(2), 306-315, 2018
2018 Liu SM, Lin CH, (Lu J, Lin IY, Tsai MS, Chen MH, Ma N, miR-596 Modulates Melanoma Growth by Regulating Cell Survival and Death., The Journal of investigative dermatology, vol. 138(4), 911-921, 2018
2018 Chang HC, Huang PH, Syu FS, Hsieh CH, Chang SL, Lu J*, Chen HC*, Critical involvement of atypical chemokine receptor CXCR7 in allergic airway inflammation., Immunology, vol. 154(2), 274-284, 2018
2018 Hung, K.-H., Woo, Y. H., Lin, I-Y., Liu, C.-H., Wang, L.-C., Chen, H.-Y., Chiang, B.-L., Lin, K.-I)*, The KDM4A/KDM4C/NF-κB and WDR5 epigenetic cascade regulates the activation of B cells, NUCLEIC ACIDS RESEARCH, vol. 46(11), 5547-5560, 2018
2018 Tsai, M.-S., Chiang, M.-T., Tsai, D.-L., Yang, C.-W., Hou, H.-S., Li, Y.-R., Chang, P.-C., Lin, H.-H., Chen, H.-Y., Hwang, I.-S., Wei, P.-K., Hsu, C.-P., (Lin, K.-I, Liu, F.-T., Chau, L.-Y, Galectin-1 restricts vascular smooth muscle cell motility via modulating adhesion force and focal adhesion dynamics, Scientific Reports, vol. 8(1), 11497, 2018
2018 Ko, Y.-A., Chan, Y.-H., Liu, C.-H., Liang, J.-J., Chuang, T.-H., Hsueh, Y.-P., Lin, Y.-L., Lin, K.-I)*, Blimp-1-mediated pathway promotes Type I IFN production in plasmacytoid dendritic cells by targeting to Interleukin-1 receptor-associated kinase M, FRONTIERS IN IMMUNOLOGY, vol. 9, 1828, 2018
2018 N. S. Hsu, Y. L. Wang, K. H. Lin, C. F. Chang, S. Y. Lyu, L. J. Hsu, Y. C. Liu, C. Y. Chang, C. J. Wu, T. L. Li*, The mesomeric effect of thiazolium on non-Kekule diradicals in Pichia stipitis transketolase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 57(7), 1802-1807, 2018
2018 N. S. Hsu, Y. L. Wang, K. H. Lin, C. F. Chang, S. C. Ke, S. Y. Lyu, L. J. Hsu, Y. S. Li, S. C. Chen, K. C. Wang, T. L. Li*, Evidence of diradicals involved in the yeast transketolase catalyzed keto-transferring reactions, CHEMBIOCHEM, vol. 19(22), 2395-2402, 2018
2018 Wu YW, Hsu KC, Lee HY, Huang TC, Lin TE, Chen YL, Sung TY, Liou JP, (Hwang-Verslues WW, Pan SL, Huang-Fu WC, A novel dual HDAC6 and tubulin inhibitor, MPT0B451, displays anti-tumor ability in human cancer cells in vitro and in vivo, FRONTIERS IN PHARMACOLOGY, vol. 9, 205, 2018
2018 Abdul F.F.-S., Tu S.-H., Chen L.-C., Liu Y.-R., Lin Y.-K., Chang H.-L., Chang H.-W., Wu C.-H., Hwang-Verslues W.W., Ho Y.-S., The Impact of the effectiveness of GATA3 as a prognostic factor in breast cancer, Human Pathology, vol. 80, 219-230, 2018
2018 Yu, C.-W., Cheng, K.-C., Chen, L.-C., Lin, M.-X., Chang, Y.-C., (Hwang-Verslues, W.W.)*, Pro-inflammatory cytokines IL-6 and CCL2 suppress expression of circadian gene Period2 in mammary epithelial cells, BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, vol. 1861(11), 1007-1017, 2018
2018 Chen YL, Hu CM, Hsu JT, Chang CC, Huang TY, Chiang PH, Chen WY, Chang YT, Chang MC, Tien YW, Lee EY, Jeng YM, Lee WH, Cellular 5-hydroxylmethylcytosine content determines tumorigenic potential and prognosis of pancreatic ductal adenocarcinoma, American journal of cancer research., vol. 8, 2548-2563, 2018
2018 Zulueta, M. M. L.*; Chyan, C.-L.; (Hung, S.-C.*, Structural Analysis of Synthetic Heparan Sulfate Oligosaccharides with Fibroblast Growth Factors and Heparin-Binding Hemagglutinin, Curr. Opin. Struct. Biol., vol. 50, 126-133, 2018
2018 Wang, C.-C.*; Sabbavarapu, N. M.; Podilapu, A. R.; Liao, P.-H.; (Hung, S.-C.*, One-Pot Protection, Glycosylation and Protection-Glycosylation Strategies of Carbohydrates, Chem. Rev., vol. 118, 8025-8104, 2018
2018 Li-Yuan Hung, Yen-Ju Chen, Te-Lun Mai, Chia-Ying Chen, Min-Yu Yang, Tai-Wei Chiang, Yi-Da Wang, Trees-Juen Chuang*, An evolutionary landscape of A-to-I RNA editome across metazoan species, Genome Biology and Evolution, vol. 10(2), 521-537, 2018
2018 Chuang Trees-Juen*); Chen, Yen-Ju; Chen, Chia-Ying; Mai, Te-Lun; Wang, Yi-Da; Yeh, Chung­-Shu; Yang, Min-Yu; Hsiao, Yu-Ting; Chang, Tien-Hsien; Kuo, Tzu-Chien; Cho, Hsin-Hua; Shen, Chia-Ning; Kuo, Hung-Chih; Lu, Mei-Yeh; Chen, Yi-Hua; Hsieh, Shan-Chi; Chiang, Tai-Wei, Integrative transcriptome sequencing reveals extensive alternative trans-splicing and cis-backsplicing in human cells, NUCLEIC ACIDS RESEARCH, vol. 46(7), 3671-3691, 2018
2018 Li HY, Lee JD, Chen CW, Sun YC, Cheng WC, Synthesis of (3S,4S,5S)-trihydroxylpiperidine derivatives as enzyme stabilizers to improve therapeutic enzyme activity in Fabry patient cell lines., European journal of medicinal chemistry, vol. 144, 626-634, 2018
2018 Wu WS, Cheng WC, Cheng TR, Wong CH, Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase., Journal of the American Chemical Society, vol. 140(8), 2752-2755, 2018
2018 Cheng WC, Lin CK, Li HY, Chang YC, Lu SJ, Chen YS, Chang SY, A combinatorial approach towards the synthesis of non-hydrolysable triazole-iduronic acid hybrid inhibitors of human alpha-l-iduronidase: discovery of enzyme stabilizers for the potential treatment of MPSI., CHEMICAL COMMUNICATIONS, vol. 54(21), 2647-2650, 2018
2018 Ming-Che Lee, Wan-Cheng Yu, Yao-Hsiang Shih, Chun-Yu Chen, Zhong-Hong Guo, Shing-Jong Huang, Jerry C. C. Chan, Yun-Ru Chen)*, Zinc ion rapidly induces toxic, off-pathway amyloid-β oligomers distinct from amyloid-β derived diffusible ligands in Alzheimer’s disease, Scientific Reports, vol. 8, 4772, 2018
2018 Chia-Jung Kuo, Hsu-Cheng Chiang, Chi-Ang Tseng, Chin-Fu Chang, Rajesh Kumar Ulaganathan, Tzu-Ting Ling, Yu-Jen Chang, Chiao-Chen Chen, (Yun-Ru Chen, Yit-Tsong Chen*., A Lipid-Modified Graphene-Transistor Biosensor for Monitoring Amyloid-β Aggregation, ACS APPLIED MATERIALS & INTERFACES, vol. 10(15), 12311-12316, 2018
2018 Ling-Hsien Tu, Ning-Hsuan Tseng, Ya-Ru Tsai, Tien-Wei Lin, Yi-Wei Lo, Jien-Lin Charng, Hua-Ting Hsu, Yu-Sheng Chen, Rong-Jie Chen, Ying-Da Wu, Yi-Tsu Chan, Chang-Shi Chen, Jim-Min Fang, *, Yun-Ru Chen)*, Rationally Designed Divalent Caffeic Amide Inhibits Amyloid-β Fibrillization, Induce Fibril Dissociation, and Ameliorate Cytotoxicity, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 158, 393-404, 2018
2018 Wei Chen, Chi-An Cheng, Bai-Yu Lee, Daniel L Clemens, Wen-Yen Huang, Marcus A Horwitz, Jeffrey I Zink*, Facile Strategy Enabling Both High Loading and High Release Amounts of the Water-Insoluble Drug Clofazimine Using Mesoporous Silica Nanoparticles, ACS Applied Materials & Interfaces, vol. 10, 31870-31881, 2018
2018 Li Shuang, Lee Yuan-Chin Amy, Li Qian, (Chen Chien-Jen, Hsu Wan-Lun, Lou Pen-Jen, Zhu Cairong, Pan Jian, Shen Hongbing, Ma Hongxia, Cai Lin, He Baochang, Wang Yu, Zhou Xiaoyan, Ji Qinghai, Zhou Baosen, Wu Wei, Ma Jie, Boffetta Paolo, Zhang Zuo-Feng, Dai Min, Hashibe Mia, Tea, coffee, and head and neck cancer risk in a multicenter study in east Asia, Oral Cancer, vol. 2(1-2), 57-65, 2018
2018 Liu Z, Coghill AE, Pfeiffer RM, Proietti C, Hsu WL, Chien YC, Lekieffre L, Krause L, Yu KJ, Lou PJ, Wang CP, Mulvenna J, Middeldorp JM, Bethony J, (Chen CJ, Doolan DL, Hildesheim A, Patterns of Interindividual Variability in the Antibody Repertoire Targeting Proteins Across the Epstein-Barr Virus Proteome., The Journal of infectious diseases, vol. 217(12), 1923-1931, 2018
2018 Coghill AE, Pfeiffer RM, Proietti C, Hsu WL, Chien YC, Lekieffre L, Krause L, Teng A, Pablo J, Yu KJ, Lou PJ, Wang CP, Liu Z, (Chen CJ, Middeldorp J, Mulvenna J, Bethony J, Hildesheim A, Doolan DL, Identification of a Novel, EBV-Based Antibody Risk Stratification Signature for Early Detection of Nasopharyngeal Carcinoma in Taiwan., Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 24(6), 1305-1314, 2018
2018 Lee MH, Huang YH, Chen HY, Khor SS, Chang YH, Lin YJ, Jen CL, Lu SN, Yang HI, Nishida N, Sugiyama M, Mizokami M, Yuan Y, L'Italien G, Tokunaga K, (Chen CJ, Human leukocyte antigen variants and risk of hepatocellular carcinoma modified by hepatitis C virus genotypes: A genome-wide association study., Hepatology (Baltimore, Md.), vol. 67(2), 651-661, 2018
2018 Chen CJ, Global elimination of viral hepatitis and hepatocellular carcinoma: opportunities and challenges., Gut, vol. 67(4), 595-598, 2018
2018 Coghill AE, Bu W, Hsu WL, Nguyen H, Yu KJ, Chien YC, (Chen CJ, Cohen JI, Hildesheim A, Evaluation of Total and IgA-Specific Antibody Targeting Epstein-Barr Virus Glycoprotein 350 and Nasopharyngeal Carcinoma Risk., The Journal of infectious diseases, vol. 218(6), 886-891, 2018
2018 Coghill AE, Hsu WL, Yang Q, Wang CP, Lou PJ, Yu KJ, Yu G, Diehl SR, (Chen CJ, Goldstein AM, Hildesheim A, Elevated antibodies against Epstein-Barr virus among individuals predicted to carry nasopharyngeal carcinoma susceptibility variants., The Journal of general virology, vol. 99(9), 1268-1273, 2018
2018 NCD Risk Factor Collaboration (NCD-RisC, Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants., International journal of epidemiology, vol. 47(3), 872-883i, 2018
2018 Chu YJ, Yang HI, Wu HC, Lee MH, Liu J, Wang LY, Lu SN, Jen CL, You SL, Santella RM, (Chen CJ, Aflatoxin B1 exposure increases the risk of hepatocellular carcinoma associated with hepatitis C virus infection or alcohol consumption., European journal of cancer (Oxford, England : 1990), vol. 94, 37-46, 2018
2018 Lin YJ, Chang CL, Chen LC, Hu HH, Liu J, Korenaga M, Huang YH, Jen CL, Su CY, Nishida N, Sugiyama M, Lu SN, Wang LY, Yuan Y, L'Italien G, Yang HI, Mizokami M, (Chen CJ, Lee MH, A Glycomarker for Short-term Prediction of Hepatocellular Carcinoma: A Longitudinal Study With Serial Measurements., Clinical and translational gastroenterology, vol. 9(9), 183, 2018
2018 Chuang, T.-J., Chen, Y.-J., Chen, C.-Y., Mai, T.-L., Wang, Y.-D., Yeh, C.-S., Yang, M.-Y., Hsiao, Y.-T., (Chang, T.-H., Kuo, T.-C., Cho, H.-H., Shen, C.-N., Kuo, H.-C., Lu, M.-Y., Chen, Y.-H., Hsieh, S.-C., Chiang, T.-W., Integrative transcriptome sequencing reveals extensive alternative trans-splicing and cis-backsplicing in human cells, Nucleic Acids Research, vol. 46(7), 3671-3691, 2018