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Tajan M, Hennequart M, Cheung EC, Zani F, Hock AK, Legrave N, Maddocks ODK, Ridgway RA, Athineos D, Suarez-Bonnet A, Ludwig RL, Novellasdemunt L, Angelis N, Li VSW, Vlachogiannis G, Valeri N, Mainolfi N, Suri V, Friedman A, Manfredi M, Blyth K, Sansom OJ, Vousden KH, Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy., Nature communications, vol. 12(1), 366, 2021 |
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Hsien-I Lin*, (Ying-Chih Chang, Colorectal cancer detection by immunofluorescence images of circulating tumor cells, Ain Shams Engineering Journal, vol. 12(3), 2673-2683, 2021 |
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Tsai, Wen-Sy, Tsung-Fu Hung, Jia-Yang Chen, Shu-Huan Huang, Ying-Chih Chang, Early Detection and Dynamic Changes of Circulating Tumor Cells in Transgenic NeuN Transgenic (NTTg) Mice with Spontaneous Breast Tumor Development, Cancers, vol. 13, 3294, 2021 |
2021 |
Jan JT, Cheng TR, Juang YP, Ma HH, (Wu YT, Yang WB, Cheng CW, Chen X, Chou TH, Shie JJ, Cheng WC, Chein RJ, Mao SS, Liang PH, Ma C, Hung SC, Wong CH, Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection., Proceedings of the National Academy of Sciences of the United States of America, vol. 118 (5), e2021579118, 2021 |
2021 |
Huang YL, Huang MT, Sung PS, Chou TY, Yang RB, Yang AS, Yu CM, Hsu YW, Chang WC, (Hsieh SL)*, Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection, Communications biology, vol. 4(1): 229, 1-13, 2021 |
2021 |
Pan YG, Huang MT, P. Sekar, Huang DY, Lin WW, (Hsieh SL)*, Decoy Receptor 3 Inhibits Monosodium Urate-Induced NLRP3 Inflammasome Activation via Reduction of Reactive Oxygen Species Production and Lysosomal Rupture, FRONTIERS IN IMMUNOLOGY, vol. 12: 638676, 1-16, 2021 |
2021 |
Tsai TY, Huang MT, Sung PS, Peng CY, Tao MH, Yang HI, Chang WC, Yang AS, Yu CM, Lin YP, Ching-Yu Bau3, Huang CJ, Pan MH, Wu CY, Hsiao CD, Yeh YH, Shiteng Duan, James C Paulson, (Hsieh SL)*, Siglec-3 (CD33) is the immune checkpoint receptor in HBV infection, JOURNAL OF CLINICAL INVESTIGATION, vol. 131(11), 141965, 2021 |
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Sung PS, (Hsieh SL)*, C-type lectins and extracellular vesicles in virus-induced NETosis, JOURNAL OF BIOMEDICAL SCIENCE, vol. 28(1), 46, 2021 |
2021 |
Sun CP, Jan JT, Wang IH, Ma HH, Ko HY, Wu PY, Kuo TJ, Liao HN, Lan YH, Sie ZL, Chen YH, Ko YA, Liao CC, Chen LY, Lee IJ, Tsung SI, Lai YJ, Chiang MT, Liang JJ, Liu WC, Wang JR, Yuan PY, Lin YS, Tsai YC, (Hsieh SL, Li CW, Wu HC, Ko TM, Lin YL, Tao MH*, Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19, PLOS PATHOGENS, vol. 17(8):, e1009758, 2021 |
2021 |
Chen WY, Wen YC, Lin SR, Yeh HL, Jiang KC, Chen WH, Lin YS, Zhang Q, Liew PL, (Hsiao M, Huang J, Liu YN, Nerve Growth Factor Interacts with CHRM4 and Promotes Neuroendocrine Differentiation of Prostate Cancer and Castration Resistance, COMMUNICATIONS BIOLOGY, vol. Jan 4;4(1), 22, 2021 |
2021 |
Cheng CL, Chan MH, Feng SJ, (Hsiao M*, Liu RS, Long-Term Near-Infrared Signal Tracking of the Therapeutic Changes of Glioblastoma Cells in Brain Tissue with Ultrasound-Guided Persistent Luminescent Nanocomposites, ACS APPLIED MATERIALS & INTERFACES, vol. Feb 10;13(5), 6099-6108, 2021 |
2021 |
Pan KF, Lee WJ, Chou CC, Yang YC, Chang YC, Chien MH, (Hsiao M, Hua KT, Direct Interaction of β‐catenin with Nuclear ESM1 Supports Stemness of Metastatic Prostate Cancer, EMBO JOURNAL, vol. Feb15;40(4), e105450, 2021 |
2021 |
Chen CL, Chen CC, Yu WH, Chen SH, Chang YC, Hsu TI, (Hsiao M, Yeh CY, Chen CY, An Annotation-free Whole-slide Training Approach to Pathological Classification of Lung Cancer Types using Deep Learning, NATURE COMMUNICATIONS, vol. Feb 19;12(1), 1193, 2021 |
2021 |
Li LJ, Chang WM, (Hsiao M)*, Aberrant Expression of microRNA Clusters in Head and Neck Cancer Development and Progression: Current and Future Translational Impacts - [INVITED REVIEW], PHARMACEUTICALS, vol. Feb 27;14(3), 194, 2021 |
2021 |
Chuang HH, Zhen YY, Tsai YC, Chuang CH, Huang MS, (Hsiao M)*, Yang CJ, Targeting Pin1 for Modulation of Cell Motility and Cancer Therapy - [INVITED REVIEW], BIOMEDICINES, vol. Mar 31;9(4), 359, 2021 |
2021 |
Huang WT, Su TY, Chan MH, Tsai JY, Do YY, Huang PL, (Hsiao M)*, Liu RS, Near-infrared Nanophosphor Embedded in Mesoporous Silica Nanoparticle with High Light-Harvesting Efficiency to Promote Dual Photosystem, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. Mar 22;60(13):6955, 6959, 2021 |
2021 |
Pan JK, Lin CH, Kuo YL, Ger LP, Cheng HC, Yao YC, (Hsiao M, Lu PJ, MiR-211 Determines Brain Metastasis Specificity through SOX11/NGN2 Axis in Triple-negative Breast Cancer, ONCOGENE, vol. Mar;40(9):1737, 1751, 2021 |
2021 |
Lin TC, (Hsiao M)*, Leptin and Cancer: Updated Functional Roles in Carcinogenesis, Therapeutic Niches, and Developments - [INVITED REVIEW], INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. Mar 11;22(6), 2870, 2021 |
2021 |
Yang YC, Chien MH, Lai TC, Tung MC, Jan YH, Chang WM, Jung SM, Chen MH, Yeh CN, (Hsiao M)*, Proteomics-based Identification of TMED9 Is Linked to Vascular Invasion and Poor Prognoses in Patients with Hepatocellular Carcinoma, JOURNAL OF BIOMEDICAL SCIENCE, vol. Apr 22;28(1), 29, 2021 |
2021 |
Yuan LT, Lee WJ, Yang YC, Chen BR, Yang CY, Chen MW, Chen JQ, (Hsiao M, Chien MH, Hua KT, Histone Methyltransferase G9a-Promoted Progression of Hepatocellular Carcinoma Is Targeted by Liver-Specific Hsa-miR-122, CANCERS, vol. 13(10), 2376, 2021 |
2021 |
Chang YC, Chan MH, Li CH, Yang CJ, Tseng YW, Tsai HF, Chiou J, (Hsiao M)*, Metabolic Protein Phosphoglycerate Kinase 1 Confers Lung Cancer Migration by Directly Binding to HIV Tat Specific Factor 1, CELL DEATH DISCOVERY, vol. Jun 5;7(1), 135, 2021 |
2021 |
Chan MH, Chen W, Li CH, Fang CY, Chang YC, Wei DH, Liu RS, (Hsiao M)*, An Advanced In Situ Magnetic Resonance Imaging and Ultrasonic Theranostics Nanocomposite Platform: Crossing the Blood–Brain Barrier and Improving the Suppression of Glioblastoma Using Iron-Platinum Nanoparticles in Nanobubbles, ACS APPLIED MATERIALS & INTERFACES, vol. Jun 16;13(23), 26759-26769, 2021 |
2021 |
Chung SY, Hung YP, Pan YR, Chang YC, Wu CE, Hsu DS, Chang PM, Lu ML, Huang CY, Su Y, (Hsiao M, Yeh CN, Chen MH, Ruxolitinib Combined with Gemcitabine against Cholangiocarcinoma Growth via the JAK2/STAT1/3/ALDH1A3 Pathway, BIOMEDICINES, vol. 9(8), 885, 2021 |
2021 |
Chang YC, Chan MH, Li CH, Fang CY, (Hsiao M)*, Chen CL, Exosomal Components and Modulators in Colorectal Cancer: Novel Diagnosis and Prognosis Biomarkers [INVITED REVIEW], BIOMEDICINES, vol. 9(8), 931, 2021 |
2021 |
Hsu HJ, Tung CP, Yu CM, Chen CY, Chen HS, Huang YC, Tsai PH, Lin SI Peng HP, Chiu YK, Tsou YL, Kuo WY, Jian JW, Hung FH, Hsieh CY, (Hsiao M, Chuang SS, Shen CN, Wang YA, Yang AS, Eradicating Mesothelin-positive Human Gastric and Pancreatic Tumors in Xenograft Models with Optimized Anti-mesothelin Antibody–drug Conjugates from Synthetic Antibody Libraries, SCIENTIFIC REPORTS, vol. 11(1), 15430, 2021 |
2021 |
Kuo KT, Yeh CT, Chen TT, Satriyo PB, Wang CH, Wu ATH, Chao TY, Lee KY, (Hsiao M, Wang LS, Bruton’s Tyrosine Kinase (BTK) Mediates Resistance to EGFR Inhibition in Non-Small Cell Lung Cancer, ONCOGENESIS, vol. 10(7), 56, 2021 |
2021 |
Chi LH, Wu ATH, (Hsiao M)*, Li YC, A Transcriptomic Analysis of Head and Neck Squamous Cell Carcinomas for Prognostic Indications, JOURNAL OF PERSONALIZED MEDICINE, vol. 11(8), 782, 2021 |
2021 |
Li CH, Hsu TI, Chang YC, Chan MH, Lu PJ, (Hsiao M)*, Stationed or Relocating: The Seesawing EMT/MET Determinants from Embryonic Development to Cancer Metastasis [INVITED REVIEW], BIOMEDICINES, vol. Sep 18;9(9), 1265, 2021 |
2021 |
Li CH, Chang YC, Chan MH, Yang YF, Liang SM, (Hsiao M)*, Galectins in Cancer and the Microenvironment: Functional Roles, Therapeutic Developments, and Perspectives [INVITED REVIEW], BIONMEDICINES, vol. Sep 4;9(9), 1159, 2021 |
2021 |
Chen TH, Chen YJ, Huang TS, (Hsiao M, Lin CC, Liu YP, Does Positive Feeling Lead to More Impulsiveness? - Implication of Previous Rewarded Experience on Location-dependent Motoric Impulsivity, CHINESE JOURNAL OF PHYSIOLOGY, vol. 64(5), 218-224, 2021 |
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Wu ATH, Huang HS, Wen YT, Lawal B, Mokgautsi N, Huynh TT, (Hsiao M, Wei L, A Preclinical Investigation of GBM-N019 as a Potential Inhibitor of Glioblastoma via Exosomal mTOR/CDK6/STAT3 Signaling., CELLS, vol. Sep 11;10(9), 2391, 2021 |
2021 |
Tsai HF, Chang YC, Li CH, Chan MH, Chen CL, Tsai WC, (Hsiao M)*, Type V Collagen Alpha 1 Chain Promotes the Malignancy of Glioblastoma through PPRC1-ESM1 Axis Activation and Extracellular Matrix Remodeling, CELL DEATH DISCOVERY, vol. Oct. 26;7(1), 313, 2021 |
2021 |
Pai S, Yadav VK, Kuo KT, Pikatan NW, Lin CS, Chien MH, Lee WH, (Hsiao M, Chiu SC, Yeh CT, Tsai JT, PDK1 Inhibitor BX795 Improves Cisplatin and Radio-Efficacy in Oral Squamous Cell Carcinoma by Downregulating the PDK1/CD47/Akt-Mediated Glycolysis Signaling Pathway., INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. Oct. 25;22(21), 11492, 2021 |
2021 |
Chan MH, Lu CN, Chung YL, Chang YC, Li CH, Chen CL, Wei DH, (Hsiao M)*, Magnetically Guided Theranostics: Montmorillonite-based Iron/platinum Nanoparticles for Enhancing In Situ MRI Contrast and Hepatocellular Carcinoma Treatment, JOURNAL OF NANOBIOTECHNOLOGY, vol. Oct 9;19(1), 308, 2021 |
2021 |
Yeh YC, Lawal B, (Hsiao M, Huang TH, Huang CF, Identification of NSP3 (SH2D3C) as a Prognostic Biomarker of Tumor Progression and Immune Evasion for Lung Cancer and Evaluation of Organosulfur Compounds from Allium sativum L. as Therapeutic Candidates., BIOMEDICINES, vol. Oct 30;9(11), 1582, 2021 |
2021 |
Wen YC, Liu YN, Yeh HL, Chen WH, Jiang KC, Lin SR, Huang J, (Hsiao M, Chen WY*, TCF7L1 Regulates Cytokine Response and Neuroendocrine Differentiation of Prostate Cancer, ONCOGENESIS, vol. Nov 20;10(11), 81, 2021 |
2021 |
Lin MY, Chang YC, Wang SY, Yang MH, Chang CH, (Hsiao M, Kitsis RN, Lee YJ, OncomiR miR-182-5p Enhances Radiosensitivity by Inhibiting the Radiation-Induced Antioxidant Effect through SESN2 in Head and Neck Cancer., ANTIOXIDANTS, vol. Nov. 14;10(11), 1808, 2021 |
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Chan MH, Chen BG, Ngo LT, Huang WT, Li CH, Liu RS, (Hsiao M)*, Natural Carbon Nanodots: Toxicity Assessment and Theranostic Biological Application [INVITED REVIEW], PHARMACEUTICS, vol. Nov 5;13(11), 1874, 2021 |
2021 |
V. Gannedi, B. Villuri, S. Reddy, C.-C. Ku, S.-C. Hung, Practical Remdesivir Synthesis through One-Pot Organocatalyzed Asymmetric (S)-P-Phosphoramidation., The Journal of organic chemistry, vol. 86(7), 4977–4985, 2021 |
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S. S. Shivatare, T.-J. Chen, Y.-Y. Cheng, V. S. Shivatare, T.-I. Tsai, H.-Y. Chaung, C.-Y. Wu, Immunogenicity Evaluation of N-Glycans Recognized by HIV Broadly Neutralizing Antibodies., ACS chemical biology, vol. 16(10), 2016-2025, 2021 |
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J.-T. Jan, T.-J. R. Cheng, Y.-P. Juang, H.-H. Ma, Y.-T. Wu, W.-B. Yang, C.-W. Cheng, X. Chen, T.-H. Chou, J.-J. Shie, W.-C. Cheng, R.-J. Chein, S.-S. Mao, P.-H. Liang, C. Ma, S.-C. Hung, Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection., Proceedings of the National Academy of Sciences of the United States of America, vol. 118(5), e2021579118, 2021 |
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C.-W. Lin, Y.-J. Wang, T.-Y. Lai, T.-L. Hsu, S.-Y. Han, H.-C. Wu, C.-N. Shen, V. Dang, M.-W. Chen, L.-B. Chen, Homogeneous antibody and CAR-T cells with improved effector functions targeting SSEA-4 glycan on pancreatic cancer., Proceedings of the National Academy of Sciences of the United States of America, vol. 118(50), e-e2114774118, 2021 |
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R.-H. Lee, Y.-J. Wang, T.-Y. La, T.-L. Hsu, P.-K. Chuang, Combined Effect of Anti-SSEA4 and Anti-Globo H Antibodies on Breast Cancer Cells., ACS chemical biology, vol. 16(8), 1526-1537, 2021 |
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C.-W. Chang, M.-H. Lin, C.-K. Chan, K.-Y. Su, C.-H. Wu, W.-C. Lo, S. Lam, Y.-T. Cheng, P.-H. Liao, C.-C. Wang, Automated Quantification of Hydroxyl Reactivities: Prediction of Glycosylation Reactions., Angewandte Chemie (International ed. in English), vol. DOI: 10.1002/anie.202013909, 2021 |
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Y.-A. Ko, Y.-H. Yu, Y.-F. Wu, Y.-C. Tseng, C.-L. Chen, K.-S. Goh, H.-Y. Liao, T.-H. Chen, T.-J. R. Cheng, A.-S. Yang, C. Ma, K.-I. Lin, A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells., PLoS pathogens, vol. 17(8), e1009724, 2021 |
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Jan JT, Cheng TR, Juang YP, Ma HH, Wu YT, (Yang WB, Cheng CW, Chen X, Chou TH, Shie JJ, Cheng WC, Chein RJ, Mao SS, Liang PH, Ma C, Hung SC, Wong CH, Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection., Proceedings of the National Academy of Sciences of the United States of America, vol. 118 (5), e2021579118, 2021 |
2021 |
Ozdemir A, Lin JL, Gulfen M, Chen CH*, Investigation of solvent microparticle formation in spray ionization-quadrupole ion trap-mass spectrometry., Journal of mass spectrometry : JMS, vol. 56(11), e4785, 2021 |
2021 |
Lai SH, Chu ML, Lin JL*, Chen CH, Development of a focused high-energy macromolecular ion beam., The Analyst, vol. 146(9), 2936-2944, 2021 |
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Kuo CM, Wei SY, Du SH, (Lin JL, Chu CH, Chen CH, Tai JH, Chen SH, Comprehensive Workflow for Mapping Disulfide Linkages Including Free Thiols and Error Checking by On-Line UV-Induced Precolumn Reduction and Spiked Control., Analytical chemistry, vol. 93(3), 1544-1552, 2021 |
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Lee RH, Wang YJ, Lai TY, Hsu TL, Chuang PK, Wu HC, Wong CH, Combined Effect of Anti-SSEA4 and Anti-Globo H Antibodies on Breast Cancer Cells., ACS Chemical Biology, vol. 16(8), 1526-1537, 2021 |
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Lin Chih-Wei, Wang Yu-Jen, Lai Ting-Yen, Hsu Tsui-Ling, Han Shin-Ying, Wu Han-Chung, Shen Chia-Ning, Dang Van, Chen Ming-Wei, Chen Lan-Bo, Wong Chi-Huey, Homogeneous antibody and CAR-T cells with improved effector functions targeting SSEA-4 glycan on pancreatic cancer, Proceedings of the National Academy of Sciences, vol. 118(50), e2114774118, 2021 |
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Lin JH, Wen CP, Jiang CQ, Yuan JM, Chen CJ, Ho SY, Gao W, Zhang W, Wang R, Chien YC, Xu L, Wu X, Jin YL, Koh WP, Hsu WL, Zhu F, Wen C, Zhu T, Lee JH, Mai ZM*, Lung ML, Lam TH, Smoking and nasopharyngeal cancer: individual data meta-analysis of six prospective studies on 334 935 men., International journal of epidemiology, vol. 50(3), 975-986, 2021 |
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Lee MH*, Huang YH, Coghill AE, Liu Z, Yu KJ, Hsu WL, Chien YC, Wang CP, Chen TC, Chen CJ, Hildesheim A, Epstein-Barr Virus-Based Nasopharyngeal Carcinoma (NPC) Risk Prediction Scores Are Elevated in NPC Multiplex Family Members in Taiwan., The Journal of infectious diseases, vol. 223(3), 441-444, 2021 |
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Chang SY, Huang KY, Chao TL, Kao HC, Pang YH, Lu L, Chiu CL, Huang HC, (Cheng TR, Fang JM, * Yang PC*, Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses., Scientific reports, vol. 11(1), 8692, 2021 |
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Shivatare SS, Cheng TR, Cheng YY, Shivatare VS, Tsai TI, Chuang HY, Wu CY, Wong CH*, Immunogenicity Evaluation of N-Glycans Recognized by HIV Broadly Neutralizing Antibodies., ACS chemical biology, vol. 16(10), 2016-2025, 2021 |
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Jan JT, (Cheng TR, Juang YP, Ma HH, Wu YT, Yang WB, Cheng CW, Chen X, Chou TH, Shie JJ, Cheng WC, Chein RJ, Mao SS, Liang PH, Ma C, Hung SC, Wong CH, Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection., Proceedings of the National Academy of Sciences of the United States of America, vol. 118(5), e2021579112, 2021 |
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Ko YA, Yu YH, Wu YF, Tseng YC, Chen CL, Goh KS, Liao HY, Chen TH, (Cheng TR, Yang AS, Wong CH, Ma C, Lin KI, A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells., PLoS pathogens, vol. 17(8), e1009724, 2021 |
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Lin MH, Cho CC, Chiu YC, Chien CY, Huang YP, (Chang CF, Hsu CH, Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites., Communications biology, vol. 4(1), 123, 2021 |
2021 |
Maksimov EG, Laptev GY, Blokhin DS, Klochkov VV, Slonimskiy YB, Sluchanko NN, Friedrich T, (Chang CF, Polshakov VI, NMR resonance assignment and backbone dynamics of a C-terminal domain homolog of orange carotenoid protein., Biomolecular NMR assignments, vol. 15(1), 17-23, 2021 |
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Lin MH, Huang YP, (Chang CF)*, Hsu CH*, NMR assignments of the macro domain from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)., Biomolecular NMR assignments, vol. 15(1), 137-142, 2021 |
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Li Hao-Kai, (Chang Chi-Fon, Lin Hsuan-Ju, Lin Jung-Lee, Lee Yu-Ting, Wu Yu-Hsuan, Liu Chiao-Yen, Lin Tze-Chia, Hsu Pang-Hung, Lin Hong-Ting Victor, Conversion of a Thiol Precursor into Aroma Compound 4-mercapto-4-methyl-2-pentanone Using Microbial Cell Extracts, Fermentation, vol. 7(3), 129, 2021 |
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Liu Z, Derkach A, Yu KJ, Yeager M, Chang YS, Chen CJ, Gyllensten U, Lan Q, Lee MH, McKay JD, Rothman N, Yang HI, Hildesheim A, Pfeiffer RM, Patterns of Human Leukocyte Antigen Class I and Class II Associations and Cancer., Cancer Research, vol. 81(4), 1148-1152, 2021 |
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Liu Matt, Tseng Tai-Chung, Jun Dae Won, Yeh Ming-Lun, Trinh Huy, Wong Grace L. H., Chen Chien-Hung, Peng Cheng-Yuan, Kim Sung Eun, Oh Hyunwoo, Kwak Min-Sun, Cheung Michael, Toyoda Hidenori, Hsu Yao-Chun, Jeong Jae Yoon, Yoon Eileen L., Ungtrakul Teerapat, Zhang Jian, Xie Qing, Ahn Sang Bong, Enomoto Masaru, Shim Jae-Jun, Cunningham Chris, Jeong Soung Won, Cho Yong Kyun, Ogawa Eiichi, Huang Rui, Lee Dong-Hyun, Takahashi Hirokazu, Tsai Pei-Chien, Huang Chung-Feng, Dai Chia-Yen, Tseng Cheng-Hao, Yasuda Satoshi, Kozuka Ritsuzo, Li Jiayi, Wong Christopher, Wong Clifford C., Zhao Changqing, Hoang Joseph, Eguchi Yuichiro, Wu Chao, Tanaka Yasuhito, Gane Ed, Tanwandee Tawesak, Cheung Ramsey, Yuen Man-Fung, Lee Hyo-Suk, Yu Ming-Lung, Kao Jia-Horng, (Yang Hwai-I, Nguyen Mindie H., Transition rates to cirrhosis and liver cancer by age, gender, disease and treatment status in Asian chronic hepatitis B patients, Hepatology International, vol. 15(1), 71-81, 2021 |
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Polaris Observatory Collaborators, The case for simplifying and using absolute targets for viral hepatitis elimination goals., JOURNAL OF VIRAL HEPATITIS, vol. 28(1), 12-19, 2021 |
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Tsai TY, Huang MT, Sung PS, Peng CY, Tao MH, (Yang HI, Chang WC, Yang AS, Yu CM, Lin YP, Bau CY, Huang CJ, Pan MH, Wu CY, Hsiao CD, Yeh YH, Duan S, Paulson JC, Hsieh SL, SIGLEC-3 (CD33) serves as an immune checkpoint receptor for HBV infection., The Journal of clinical investigation, vol. 131(11), e141965, 2021 |
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Teng W, Chang TT, (Yang HI, Peng CY, Su CW, Su TH, Hu TH, Yu ML, Yang HC, Wu JC, Risk scores to predict HCC and the benefits of antiviral therapy for CHB patients in gray zone of treatment guidelines., Hepatology international, vol. 15(6), 1421-1430, 2021 |
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Wu HC, (Yang HI, Lin PH, Chen CJ, Santella RM, Terry MB, Reproductive and environmental exposures and the breast cancer risk in Taiwanese women., Scientific reports, vol. 11(1), 15656, 2021 |
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Chung CW, Hsiao TH, Huang CJ, Chen YJ, Chen HH, Lin CH, Chou SC, Chen TS, Chung YF, (Yang HI, Chen YM, Machine learning approaches for the genomic prediction of rheumatoid arthritis and systemic lupus erythematosus., BioData mining, vol. 14(1), 52, 2021 |
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Koshiol J, Argirion I, Liu Z, Kim Lam T, O'Brien TR, Yu K, McGlynn KA, Petrick JL, Pinto L, Chen CJ, Hildesheim A, Pfeiffer RM, Lee MH, (Yang HI, Immunologic markers and risk of hepatocellular carcinoma in hepatitis B virus- and hepatitis C virus-infected individuals., Alimentary pharmacology & therapeutics, vol. 54(6), 833-842, 2021 |
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Liu Z, Huang CJ, Huang YH, Pan MH, Lee MH, Yu KJ, Pfeiffer RM, Viard M, Yuki Y, Gao X, Carrington M, Chen CJ*, Hildesheim A*, (Yang HI*, HLA zygosity increases risk of hepatitis B virus-associated hepatocellular carcinoma., JOURNAL OF INFECTIOUS DISEASES, vol. 224(10), 1796-1805, 2021 |
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Wu S, Zeng N, Sun F, Zhou J, Wu X, Sun Y, Wang B, Zhan S, Kong Y, Jia J, You H*, (Yang HI*, Hepatocellular Carcinoma Prediction Models in Chronic Hepatitis B: A Systematic Review of 14 Models and External Validation., CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, vol. 19(12), 2499-2513, 2021 |
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Wang Z, Budhu AS, Shen Y, Wong LL, Hernandez BY, Tiirikainen M, Ma X, Irwin ML, Lu L, Zhao H, Lim JK, Taddei T, Mishra L, Pawlish K, Stroup A, Brown R, Nguyen MH, Koshiol J, Hernandez MO, Forgues M, (Yang HI, Lee MH, Huang YH, Iwasaki M, Goto A, Suzuki S, Matsuda K, Tanikawa C, Kamatani Y, Mann D, Guarnera M, Shetty K, Thomas CE, Yuan JM, Khor CC, Koh WP, Risch H, Wang XW, Yu H, Genetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome-wide association study., JGH open, vol. 5(12), 1363-1372, 2021 |
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Chen Chien-Jen, You San-Lin, Hsu Wan-Lun, (Yang Hwai-I, Lee Mei-Hsuan, Chen Hui-Chi, Chen Yun-Yuan, Liu Jessica, Hu Hui-Han, Lin Yu-Ju, Chu Yu-Ju, Huang Yen-Tsung, Chiang Chun-Ju, Chien Yin-Chu, Epidemiology of Virus Infection and Human Cancer, Recent Results Cancer Res, vol. 217, 13-45, 2021 |
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Yang HI*, Hsu YC, Editorial: incorporating liver stiffness to risk scores for HCC in patients with chronic hepatitis B treated with oral antivirals: ready to use or not?, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, vol. 53(6), 753-754, 2021 |
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Le AK, (Yang HI, Yeh ML, Jin M, Trinh HN, Henry L, Liu A, Zhang JQ, Li J, Wong C, Wong C, Cheung R, Yu ML, Nguyen MH, Development and validation of a risk score for liver cirrhosis prediction in untreated and treated chronic hepatitis B., JOURNAL OF INFECTIOUS DISEASES, vol. 223(1), 139-146, 2021 |
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Pan WC*, Yeh SY, Wu CD, Huang YT, Chen YC, Chen CJ, (Yang HI*, Association between Traffic Count and Cardiovascular Mortality: A Prospective Cohort Study in Taiwan., JOURNAL OF EPIDEMIOLOGY, vol. 31(5), 343-349, 2021 |
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Argirion I, Pfeiffer RM, Lam TK, O'Brien TR, Yu K, McGlynn KA, Petrick JL, Pinto L, Chen CJ, Lee MH, Hildesheim A, (Yang HI, Koshiol J, Association between immunologic markers and cirrhosis in individuals with chronic hepatitis B., Scientific reports, vol. 11(1), 21194, 2021 |
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Li Jie, (Yang Hwai-I, Yeh Ming-Lun, Le Michael H, Le An K, Yeo Yee Hui, Dai Chia-Yen, Barnett Scott, Zhang Jian Q, Huang Jee-Fu, Trinh Huy N, Wong Christopher, Wong Clifford, Hoang Joseph K, Cheung Ramsey, Yu Ming-Lung, Nguyen Mindie H, Association between fatty liver and cirrhosis, hepatocellular carcinoma, and HBsAg seroclearance in chronic hepatitis B, The Journal of Infectious Diseases, vol. 224 (2) , 294-302, 2021 |
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Hsu YC, Tseng CH, Huang YT, (Yang HI, Application of Risk Scores for Hepatocellular Carcinoma in Patients with Chronic Hepatitis B: Current Status and Future Perspective., SEMINARS IN LIVER DISEASE, vol. 41(3), 285-297, 2021 |
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Wei SC, Hsu WT, Chiu CH, Chang FY, Lo HR, Liao CY, (Yang HI, Chou YC, Tsai CH, Chao YC, An Integrated Platform for Serological Detection and Vaccination of COVID-19., FRONTIERS IN IMMUNOLOGY, vol. 12, 771011, 2021 |
2021 |
Liu PC, Chan C, Huang YH, Chen YJ, Liao SF, Lin YJ, Huang C, Lu SN, Jen CL, Wang LY, (Yang HI, Shen CY, Chen CJ, Lee MH, Genetic variants associated with serum alanine aminotransferase levels among patients with hepatitis C virus infection: A genome-wide association study., Journal of viral hepatitis, 2021 |
2021 |
Wu, H.H., L.H. Tsai, C.K. Huang, S.C. Huang, P.H. Hsu, M.Y. Chen, Y.I. Chen, C.M. Hu, (C.N.Shen, C.C. Lee, M.C. Chang, Y.T. Chang, Y.W. Tien, Y.M. Jeng, E. Lee, W.H. Lee*, Characterization of initial key steps of IL-17 receptor B oncogenic signaling for targeted therapy of pancreatic cancer, Science Translational Medicine, vol. 13, eabc2823, 2021 |
2021 |
Hsu HJ, Tung CP, Yu CM, Chen CY, Chen HS, Huang YC, Tsai PH, Lin SI, Peng HP, Chiu YK, Tsou YL, Kuo WY, Jian JW, Hung FH, Hsieh CY, Hsiao M, Chuang SS, (Shen CN, Wang YA, Yang AS, Eradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody-drug conjugates from synthetic antibody libraries., Scientific reports, vol. 11(1), 15430, 2021 |
2021 |
Hsu, L.J., C.L. Liu, M.L.Kuo, (C.N. Shen, C.R.Shen*, An Alternative Cell Therapy for Cancers: Induced Pluripotent Stem Cell (iPSC)-Derived Natural Killer Cells, Biomedicines, vol. 9, 1323, 2021 |
2021 |
C.W. Lin, Y.J. Wang, T.Y. Lai, T.L. Hsu, S.Y. Han, H.C. Wu, (C.N. Shen, V. Dang, M.W. Chen, L.B. Chen, C.H. Wong*, Homogeneous antibody and CAR-T cell with improved effector functions targeting SSEA-4 glycan on pancreatic cancer, Proceedings of The National Academy of Sciences of the United States of America, vol. 118(50), e2114774118, 2021 |
2021 |
Kulkarni R, Chen WC, Lee Y, Kao CF, Hu SL, Ma HH, Jan JT, Liao CC, Liang JJ, Ko HY, Sun CP, Lin YS, Wang YC, Wei SC, Lin YL, Ma C, Chao YC, Chou YC, Chang W, Vaccinia virus-based vaccines confer protective immunity against SARS-CoV-2 virus in Syrian hamsters., PLoS One, vol. 16(9), e0257191, 2021 |
2021 |
Jan JT, Cheng TR, Juang YP, Ma HH, Wu YT, Yang WB, Cheng CW, Chen X, Chou TH, Shie JJ, Cheng WC, Chein RJ, Mao SS, Liang PH*, (Ma C*, Hung SC*, Wong CH*, Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection., Proceedings of the National Academy of Sciences of the United States of America, vol. 118(5), 2021 |
2021 |
Huang KYA, Tan TK, Chen TH, Huang CG, Harvey R, Hussain S, Chen CP, Harding A, Gilbert-Jaramillo J, Liu X, Knight M, Schimanski L, Shih SR, Lin YC, Cheng CY, Cheng SH, Huang YC, Lin TY, Jan JT, (Ma C, James W, Daniels RS, McCauley JW, Rijal P, Townsend AR, Breadth and function of antibody response to acute SARS-CoV-2 infection in humans, PLOS Pathogens, vol. 17(2), e1009352, 2021 |
2021 |
Ko YA, Yu YH, Wu YF, Tseng YC, Chen CL, Goh KS, Liao HY, Chen TH, Cheng TR, Yang AS, Wong CH, Ma C, Lin KI, A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells., PLoS pathogens, vol. 17(8), e1009724, 2021 |
2021 |
Lai YP, Kuo LC, Lin BR, Lin HJ, Lin CY, Chen YT, Hsiao PW, Chang HT, Ko PC, Chen HC, Chang HY, Lu J, Ho HN, Wu-Hsieh BA, Kung JT, Chen SC, CD28 engagement inhibits CD73-mediated regulatory activity of CD8(+) T cells., Communications biology, vol. 4(1), 595, 2021 |
2021 |
Lin PY, Yang D, Chuang CH, Lin H, Chen WJ, Chen CY, Chuang TJ, Lai CY, Li LY, Schuyler SC, Lu FL, Liu YC, (Lu J)*, Comparative analyses of single-cell transcriptomic profiles between In vitro totipotent blastomere-like cells and In vivo early mouse embryonic cells, CELLS, vol. 10(11), 3111, 2021 |
2021 |
Sorzano COS*; Semchonok D; (Lin SC); Lo YC; Vilas JL; Jiménez-Moreno A; Gragera M; Vacca S; Maluenda D; Martínez M; Ramírez-Aportela E; Melero R; Cuervo A; Conesa JJ; Conesa P; Losana P; Caño LD; de la Morena JJ; Fonseca YC; Sánchez-García R; Strelak D; Fernández-Giménez E; de Isidro F; Herreros D; Kastritis PL; Marabini R; Bruce BD; Carazo JM, Algorithmic robustness to preferred orientations in single particle analysis by CryoEM, JOURNAL OF STRUCTURAL BIOLOGY, vol. 213(1), 107695-107695, 2021 |
2021 |
Jhen-Yi Hong, (Su-Chang Lin, Bai-Jiun Kuo, Yu-Chih Lo*, Structural and Biochemical Basis for Higher-Order Assembly between A20-Binding Inhibitor of NF-κB 1 (ABIN1) and M1-Linked Ubiquitins, JOURNAL OF MOLECULAR BIOLOGY, vol. 433(18), 167116-167116, 2021 |
2021 |
Lee, W., Wang, L.-T., Yen, M.-L., Hsu, P.-J., Lee, Y.-W., Liu, K.-J., (Lin, K.-I, Su, Y.-W., Sytwu, H.-K., Yen, B. L., Resident vs. nonresident multipotent mesenchymal stromal cell interactions with B lymphocytes result in disparate outcomes, Stem Cells Transi Med, vol. 10(5), 711-724, 2021 |
2021 |
Lo, L.-W., Chang, C.-W., Chiang, M.-F., Lin, I-Y., Lin, K.-I)*, Marginal zone B cells assist with neutrophil accumulation to fight against systemic Staphylococcus aureus infection, FRONTIERS IN IMMUNOLOGY, vol. 12, 636818, 2021 |
2021 |
Ko, Y.-A., Yu, Y.-H., Wu, Y.-F., Tseng, Y.-C., Chen, C.-L., Goh, K.-S, Liao, H.-Y., Chen, T.-H., Cheng, R. T.-J., Yang, A.-S., Wong, C.-H., Ma, C., Lin, K.-I)*, A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells, PLOS PATHOGENS, vol. 17(8), e1009724, 2021 |
2021 |
Hsieh, W.-C., Lai, E.-Y., Liu, Y.-T., Wang, Y.-F., Tzeng, Y.-S., Cui, L, Lai, Y.-J., Huang, H.-C., Huang, J.-H., Ni, H.-C., Tsai, D.-Y., Liang, J.-J., Liao, C.-C., Jiang, L, Liu, M.-T., Wang, J.-T., Chang, S.-Y., Chen, C.-Y., Tsai, H.-C., Chang, Y.-M., Wernig, G., Li, C.-W., (Lin, K.-I, Lin, Y.-L., Tsai, H.-K., Huang, Y.-T., Chen, S.-Y, NK cell receptor and ligand composition influences the clearance of SARS-CoV-2, JOURNAL OF CLINICAL INVESTIGATION, vol. 131 (21), e146408, 2021 |
2021 |
T. S. A. Wang*, R. Y. Wu, Y. Hong, Z. C. Wang, T. L. Li, J. J. Shie, C. C. Hsu, Labeling and characterization of phenol‐containing glycopeptides using chemoselective probes with isotope tags, CHEMBIOCHEM, vol. 22(14), 2415-2419, 2021 |