具代表性研究發表

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年度 論文名稱
2023 Zani F, Blagih J, Gruber T, Buck MD, Jones N, Hennequart M, Newell CL, Pilley SE, Soro-Barrio P, Kelly G, Legrave NM, Cheung EC, Gilmore IS, Gould AP, Garcia-Caceres C, Vousden KH, The dietary sweetener sucralose is a negative modulator of T cell-mediated responses., Nature, vol. 615(7953), 705-711, 2023
2023 Hennequart M, Pilley SE, Labuschagne CF, Coomes J, Mervant L, Driscoll PC, Legrave NM, Lee Y, Kreuzaler P, Macintyre B, Panina Y, Blagih J, Stevenson D, Strathdee D, Schneider-Luftman D, Gronroos E, Cheung EC, Yuneva M, Swanton C, Vousden KH, ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis., Cell reports, vol. 42(6), 112562, 2023
2023 Che TF, Chiu CH, Wu YC, Chen JY, Chou TY, Cheng YC, Chiang CL, Huang CS, Tuang IS, Ho YH, Hong JH, Huang YJ, Ho HL, (Chang YC)*, Proliferative ability of circulating tumor cells is a prognostic factor in Early-Stage lung adenocarcinoma., Lung Cancer (Amsterdam, Netherlands), vol. 178, 198-205, 2023
2023 Yeh PY, Chen JY, Shen MY, Che TF, Lim SC, Wang J, Tsai WS, Frank CW, Huang CJ, (Chang YC)*, Liposome-tethered supported lipid bilayer platform for capture and release of heterogeneous populations of circulating tumor cells., Journal of Materials Chemistry. B, vol. 11(34), 8159-8169, 2023
2023 Kuo NR, Hou MC, Chu WC, Yang YY, Huang CC, Li TH, Lee TY, Liu CW, Liao TL, (Hsieh SL, Lin HC, Low lymphocyte-to-monocyte ratio, calcitriol level, and CD206 level predict the development of acute-on-chronic liver failure in patients cirrhosis with acute decompensation., Journal of the Chinese Medical Association : JCMA, vol. 86(3), 265-273, 2023
2023 Furuya H, Nguyen CT, Gu R, (Hsieh SL, Maverakis E, Adamopoulos IE, Interleukin-23 Regulates Inflammatory Osteoclastogenesis via Activation of CLEC5A(+) Osteoclast Precursors., Arthritis & rheumatology (Hoboken, N.J.), vol. 75(8), 1477-1489, 2023
2023 Liao TL, Chen YM, Tang KT, Yang YY, Chen DY, Chan TH, Tsai HJ, (Hsieh SL, CLEC18A Impairs Phagocytosis by Reducing FcgammaRIIA Expression and Arresting Autophagosome-Lysosome Fusion., Microbiology Spectrum, vol. 11(3), e0290322, 2023
2023 Wang HW, Li HH, Wu SC, Tang CK, Yu HY, Chang YC, Sung PS, Liu WL, Su MP, Yu GY, Huang LR, Chen CH*, (Hsieh SL)*, CLEC5A mediates Zika virus‑induced testicular damage, JOURNAL OF BIOMEDICAL SCIENCE, vol. 30: 12, 1-16, 2023
2023 Barrios AA, Mouhape C, Schreiber L, Zhang L, Nell J, Suárez-Martins M, Schlapp G, Meikle MN, Mulet AP, Hsu TL, (Hsieh SL, Mourglia-Ettlin G, González C, Crispo M, Barth T, Casaravilla C, Jenkins SJ, Díaz Á*, Mucins Shed from the Laminated Layer in Cystic Echinococcosis Are Captured by Kupffer Cells via the Lectin Receptor Clec4F, INFECTION AND IMMUNITY, vol. 91(6), e00031-23, 2023
2023 Sung PS, Sun CP, Tao MH, (Hsieh SL)*, Inhibition of SARS-CoV-2-mediated thromboinflammation by CLEC2.Fc, EMBO MOLECULAR MEDICINE, vol. e16351, 1-16, 2023
2023 Lin Yung-Wei, Wen Yu-Ching, Hsiao Chi-Hao, Lai Feng-Ru, Yang Shun-Fa, Yang Yi-Chieh, Ho Kuo-Hao, Hsieh Feng-Koo, (Hsiao Michael, Lee Wei-Jiunn, Chien Ming-Hsien, Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition, CELLS, vol. 12(3), 352, 2023
2023 Li Chien-Hsiu, Chan Ming-Hsien, Chang Yu-Chan, (Hsiao Michael)*, Gold Nanoparticles as a Biosensor for Cancer Biomarker Determination, MOLECULES, vol. 28(1), 364, 2023
2023 Chung Shin-Yi, Chang Yu-Chan, Hsu Dennis Shin-Shian, Hung Ya-Chi, Lu Meng-Lun, Hung Yi-Ping, Chiang Nai-Jung, Yeh Chun-Nan, (Hsiao Michael, Soong John, Su Yeu, Chen Ming-Huang, A G-quadruplex Stabilizer, CX-5461 Combined with Two Immune Checkpoint Inhibitors Enhances in Vivo Therapeutic Efficacy by Increasing PD-L1 Expression in Colorectal Cancer, NEOPLASIA, vol. Jan;35, 100856, 2023
2023 Chan Ming-Hsien, Chen Bo-Gu, Huang Wen-Tse, Su Ting-Yi, (Hsiao Michael)*, Liu Ru-Shi, Tunable Single-atom Nanozyme Catalytic System for Biological Applications of Therapy and Diagnosis, MATERIALS TODAY ADVANCES, vol. 17, 100342, 2023
2023 Li Chien‐Hsiu, Fang Chih‐Yeu, Chan Ming‐Hsien, Chen Chi‐Long, Chang Yu‐Chan, (Hsiao Michael)*, The Cytoplasmic Expression of FSTL3 Correlates with Colorectal Cancer Progression, Metastasis Status and Prognosis, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, vol. 27(5), 672-686, 2023
2023 Chang Yu‐Chan, Li Chien‐Hsiu, Chan Ming‐Hsien, Fang Chih‐Yeu, Zhang Zhi‐Xuan, Chen Chi‐Long, (Hsiao Michael)*, Overexpression of Synaptic Vesicle Protein Rab GTPase 3C Promotes Vesicular Exocytosis and Drug Resistance in Colorectal Cancer Cells, MOLECULAR ONCOLOGY, vol. Mar;17(3), 422-444, 2023
2023 Wuputra Kenly, Ku Chia-Chen, Pan Jia-Bin, Liu Chung-Jung, Kato Kohsuke, Lin Ying-Chu, Liu Yi-Chang, Lin Chang-Shen, Hsiao Michael, Tai Ming-Hong, Chong Inn-Wen, Hu Huang-Ming, Kuo Chao-Hung, Wu Deng-Chyang, Yokoyama Kazunari K., Independent Signaling of Hepatoma Derived Growth Factor and Tumor Necrosis Factor-Alpha in Human Gastric Cancer Organoids Infected by Helicobacter pylori, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 24(7), 6567, 2023
2023 Lin Cheng-Han, Lin Wen-Der, Huang Yun-Chin, Chen Yu-Chia, Loh Zhu-Jun, Ger Luo-Ping, Lin Forn-Chia, Li Hao-Yi, Cheng Hui-Chuan, Lee Kuen-Haur, (Hsiao Michael, Lu Pei-Jung, Carboxyl-terminal Modulator Protein Facilitates Tumor Metastasis in Triple-negative Breast Cancer, CANCER GENE THERAPY, vol. In Press, 1-1, 2023
2023 Li Chien‐Hsiu, Fang Chih‐Yeu, Chan Ming‐Hsien, Lu Pei‐Jung, Ger Luo‐Ping, Chu Jan‐Show, Chang Yu‐Chan, Chen Chi‐Long, (Hsiao Michael)*, The Activation of EP300 by F11R Leads to EMT And Acts As A Prognostic Factor in Triple‐negative Breast Cancers, THE JOURNAL OF PATHOLOGY: CLINICAL RESEARCH, vol. 9(3), 165-181, 2023
2023 Wen Yu-Ching, Tram Van Thi Ngoc, Chen Wei-Hao, Li Chien-Hsiu, Yeh Hsiu-Lien, Thuy Dung Phan Vu, Jiang Kuo-Ching, Li Han-Ru, Huang Jiaoti, Hsiao Michael, Chen Wei-Yu, Liu Yen-Nien, CHRM4/AKT/MYCN Upregulates Interferon Alpha-17 in the Tumor Microenvironment to Promote Neuroendocrine Differentiation of Prostate Cancer, CELL DEATH & DISEASE, vol. 14(5), 304, 2023
2023 Chen Wei-Yu, Thuy Dung Phan Vu, Yeh Hsiu-Lien, Chen Wei-Hao, Jiang Kuo-Ching, Li Han-Ru, Chen Zi-Qing, Hsiao Michael, Huang Jiaoti, Wen Yu-Ching, Liu Yen-Nien, Targeting PKLR/MYCN/ROMO1 Signaling Suppresses Neuroendocrine Differentiation of Castration-resistant Prostate Cancer, REDOX BIOLOGY, vol. 62, 102686, 2023
2023 Huang Wen‐Tse, Rajendran Veeramani, Chan Ming‐Hsien, (Hsiao Michael)*, Chang Ho, Liu Ru‐Shi, Near‐Infrared Windows I and II Phosphors for Theranostic Applications: Spectroscopy, Bioimaging, and Light‐Emitting Diode Photobiomodulation, ADVANCED OPTICAL MATERIALS, vol. June ,11, 2202061, 2023
2023 Satpathy Aishwarya, Huang Wen‐Tse, Chan Ming‐Hsien, Su Ting‐Yi, Kamiński Mikołaj, Majewska Natalia, Mahlik Sebastian, Leniec Grzegorz, Kaczmarek Sławomir M., Hsiao Michael, Liu Ru‐Shi, Near‐Infrared I/II Nanophosphors with Cr3+/Ni2+ Energy Transfer for Bioimaging, ADVANCED OPTICAL MATERIALS, vol. E-Pub, 1-1, 2023
2023 Chang Yu-Chan, Chan Ming-Hsien, Yang Yi-Fang, Li Chien-Hsiu, Hsiao Michael, Glucose Transporter 4: Insulin Response Mastermind, Glycolysis Catalyst and Treatment Direction for Cancer Progression, CANCER LETTERS, vol. 563, 216179, 2023
2023 Muthiah Kayalvizhi Samuvel, Thirumurugan Senthilkumar, Lin Yu-Chien, Sakthivel Rajalakshmi, Dhawan Udesh, Wang An-Ni, (Hsiao Michael, Chung Ren-Jei, Cerium Niobate Hollow Sphere Engineered Graphitic Carbon Nitride for Synergistic Photothermal/Chemodynamic Cancer Therapy, CRYSTALS, vol. June 15; 13(6), 954, 2023
2023 Yang Yi-Chieh, Lin Yung-Wei, Lee Wei-Jiunn, Lai Feng-Ru, Ho Kuo-Hao, Chu Chih-Ying, Hua Kuo-Tai, Chen Ji-Qing, Tung Min-Che, (Hsiao Michael, Wen Yu-Ching, Chien Ming-Hsien, The RNA-binding Protein KSRP Aggravates Malignant Progression of Clear Cell Renal Cell Carcinoma Through Transcriptional Inhibition and Post-transcriptional Destabilization of the NEDD4L Ubiquitin Ligase, JOURNAL OF BIOMEDICAL SCIENCE, vol. 30(1), 68, 2023
2023 Chen Yu-Chen, Chen Chia-Ying, Chiang Tai-Wei, Chan Ming-Hsien, (Hsiao Michael, Ke Huei-Mien, Tsai Isheng Jason, Chuang Trees-Juen, Detecting Intragenic-splicing Events from Non-co-linearly Spliced Junctions by Hybrid Sequencing, NUCLEIC ACIDS RESEARCH, vol. July 27; Online ahead of print, 1, 2023
2023 Pan Jhih-Kai, Lin Wen-Der, Kuo Yao-Lung, Chen Yu-Chia, Loh Zhu-Jun, Lin Forn-Chia, Cheng Hui-Chuan, (Hsiao Michael, Lu Pei-Jung, ICAM2 Initiates Trans-blood-CSF Barrier Migration and Stemness Properties in Leptomeningeal Metastasis of Triple-negative Breast Cancer, ONCOGENE, vol. 42(39):2919-2931, 2023
2023 Lin Chen-Cheng, Yang Chiu-Ping, Cheng Pao-Yun, (Hsiao Michael, Liu Yia-Ping, Escitalopram Reversibility of the Impacts Following Chronic Stress on Central 5-HT Profiles – Implications to Depression and Anxiety, BEHAVIOURAL BRAIN RESEARCH, vol. 453, 114613, 2023
2023 Chan Ming-Hsien, Chen Bo-Gu, Li Chien-Hsiu, Huang Wen-Tse, Su Ting-Yi, Yin Lichang, Hsiao Michael, Liu Ru-Shi, Amplification of Oxidative Stress by Lipid Surface-coated Single-atom Au Nanozymes for Oral Cancer Photodynamic Therapy, NANOSCALE, vol. 15(38), 15558-15572, 2023
2023 Chiang Chi-Ling, Ma Yifan, Hou Ya-Chin, Pan Junjie, Chen Sin-Yu, Chien Ming-Hsien, Zhang Zhi-Xuan, Hsu Wei-Hsiang, Wang Xinyu, Zhang Jingjing, Li Hong, Sun Lili, Fallen Shannon, Lee Inyoul, Chen Xing-Yu, Chu Yeh-Shiu, Zhang Chi, Cheng Tai-Shan, Jiang Wen, Kim Betty Y. S., Reategui Eduardo, Lee Robert, Yuan Yuan, Liu Hsiao-Chun, Wang Kai, Hsiao Michael, Huang Chi-Ying F., Shan Yan-Shen, Lee Andrew S., James Lee L., Dual Targeted Extracellular Vesicles Regulate Oncogenic Genes in Advanced Pancreatic Cancer, NATURE COMMUNICATIONS, vol. 14(1), 6692, 2023
2023 V.-S. Shivatare, P.-K. Chuang, T.-H. Tseng, Y.-F. Zeng, H.-W. Huang, G. Veeranjaneyulu, H.-C. Wu, (C.-H. Wong*, Study on antibody Fc-glycosylation for optimal effector functions., Chemical communications (Cambridge, England), vol. 59, 5555-5558, 2023
2023 H.-W. Huang, C.-C. Chen, K.-I. Lin, T.-L. Hsu, Single Site N-Glycosylation of B Cell Maturation Antigen (BCMA) Inhibits gamma-Secretase-Mediated Shedding and Improves Surface Retention and Cell Survival., ACS chemical biology, vol. 19, 153-161, 2023
2023 V. S. Shivatare, H.-W. Huang, T.-H. Tseng, P.-K. Chuang, Y.-F. Zeng, Probing the Internalization and Efficacy of Antibody‐Drug Conjugate via Site‐Specific Fc‐Glycan Labelling of a Homogeneous Antibody Targeting SSEA‐4 Bearing Tumors, Israel Journal of Chemistry, vol. Online, ahead of print, 2023
2023 S.-W. Wang, Y.-A. Ko, C.-Y. Chen, K.-S. Liao, Y.-H. Chang, H.-Y. Lee, Y.-H. Yu, Y.-H. Lih, Y.-Y. Cheng, H.-H. Lin, T.-L. Hsu, C.-Y. Wu, K.-I. Lin, (C.-H. Wong, Mechanism of Antigen Presentation and Specificity of Antibody Cross-Reactivity Elicited by an Oligosaccharide-Conjugate Cancer Vaccine., Journal of the American Chemical Society, vol. 145(17), 9840-9849, 2023
2023 C.-W. Cheng, C.-Y. Wu, S.-W. Wang, J.-Y. Chen, C.-C. Kung, K.-S. Liao, Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA)., Proceedings of the National Academy of Sciences of the United States of America, vol. 120(49), e2314392120, 2023
2023 O. Chou, Y.-P. Juang, T.-L. Chao, S.-F. Tsai, P.-F. Chiu, C.-T. Chiou, K.-C. Tsai, S.-Y. Chang, P.-H. Liang, Isolation of Anti-SARS-CoV-2 Natural Products Extracted from Mentha canadensis and the Semi-synthesis of Antiviral Derivatives, Journal of natural products, vol. 86(6), 1428-1436, 2023
2023 Y. Zhou, K.-S. Liao, T.-Y. Chen, Y. SY Hsieh, Effective Organotin-Mediated Regioselective Functionalization of Unprotected Carbohydrates., The Journal of organic chemistry, vol. 88(11), 7141-7151, 2023
2023 Z.-R. Li, R. Li, L. Pasternack, P. Chen, Chemical Synthesis of a Keto Sugar Nucleotide, The Journal of Organic Chemistry, vol. 88(11), 7580-7585, 2023
2023 C.-C. Chen, H.-W. Huang, B.-R. Chen, Quantitative Mass Spectrometric Analysis of Hepatocellular Carcinoma Biomarker Alpha-Fetoprotein, RSC Chemical Biology, vol. published online ahead of print, published online ahead of print, 2023
2023 Kuo CM, Jen HH, Chen FY, Akbarian M, Ou TH, Liu KY, (Lin JL, Chen SH, High-performance peptide and disulfide mapping by direct injection of intact proteins using on-line coupled UV-liquid chromatography microdroplet mass spectrometry (UVLC-MMS)., ANALYTICA CHIMICA ACTA, vol. 1279, 341790, 2023
2023 Wang SW, Ko YA, Chen CY, Liao KS, Chang YH, Lee HY, Yu YH, Lih YH, Cheng YY, Lin HH, Hsu TL, Wu CY, Lin KI, Wong CH, Mechanism of Antigen Presentation and Specificity of Antibody Cross-Reactivity Elicited by an Oligosaccharide-Conjugate Cancer Vaccine., Journal of the American Chemical Society, vol. 145(17), 9840-9849, 2023
2023 Barrios AA, Mouhape C, Schreiber L, Zhang L, Nell J, Suarez-Martins M, Schlapp G, Meikle MN, Mulet AP, Hsu TL, Hsieh SL, Mourglia-Ettlin G, Gonzalez C, Crispo M, Barth TFE, Casaravilla C, Jenkins SJ, Diaz A, Mucins Shed from the Laminated Layer in Cystic Echinococcosis Are Captured by Kupffer Cells via the Lectin Receptor Clec4F., Infection and immunity, vol. 10, e0003123, 2023
2023 Lou PJ, Jacky Lam WK, Hsu WL, Pfeiffer RM, Yu KJ, Chan CML, Lee VCT, Chen TC, Terng SD, Tsou YA, Leu YS, Liao LJ, Chang YL, (Chien YC, Wang CP, Lin CY, Hua CH, Lee JC, Yang TL, Hsiao CH, Wu MS, Tsai MH, Cheng HC, Hildesheim A, Chen CJ, Chan KCA, Liu Z, Performance and Operational Feasibility of Epstein-Barr Virus-Based Screening for Detection of Nasopharyngeal Carcinoma: Direct Comparison of Two Alternative Approaches., Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 41(26), 4257-4266, 2023
2023 Argirion I, Pfeiffer RM, Proietti C, Coghill AE, Yu KJ, Middeldorp JM, Sarathkumara YD, Hsu WL, (Chien YC, Lou PJ, Wang CP, Rothman N, Lan Q, Chen CJ, Mbulaiteye SM, Jarrett RF, Glimelius I, Smedby KE, Hjalgrim H, Hildesheim A, Doolan DL, Liu Z, Comparative Analysis of the Humoral Immune Response to the EBV Proteome across EBV-Related Malignancies., Cancer Epidemiology, Biomarkers & Prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol. 32(5), 687-696, 2023
2023 Tseng YL, Lu PC, Lee CC, He RY, Huang YA, Tseng YC, (Cheng TR, Huang JJ*, Fang JM, Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera., Journal of biomedical science, vol. 30(1), 27, 2023
2023 Hsu C, Tsai HY, (Chang CF, Yang CC, Su NW, Discovery of a novel phosphotransferase from Bacillus subtilis that phosphorylates a broad spectrum of flavonoids., FOOD CHEMISTRY, vol. 400, 134001, 2023
2023 Wang YL, Chang CY, Hsu NS, Lo IW, Lin KH, Chen CL, (Chang CF, Wang ZC, Ogasawara Y, Dairi T, Maruyama C, Hamano Y, Li TL, N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry., Nature communications, vol. 14(1), 2528, 2023
2023 Tsai TY, Chen CY, Lin TW, Lin TC, Chiu FL, Shih O, Chang MY, Lin YC, Su AC, Chen CM, Jeng US, Kuo HC, (Chang CF, Chen YR, Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity., Communications biology, vol. 6(1), 767, 2023
2023 Tsai TY, Chen CY, Lin TW, Lin TC, Chiu FL, Shih O, Chang MY, Lin YC, Su AC, Chen CM, Jeng US, Kuo HC, (Chang CF, Chen YR, Author Correction: Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity., Communications biology, vol. 6(1), 1021, 2023
2023 Huang YH, Pan MH, (Yang HI*, The association between Gabapentin or Pregabalin use and the risk of dementia: an analysis of the National Health Insurance Research Database in Taiwan., FRONTIERS IN PHARMACOLOGY, vol. 14, 1128601-doi: 10.3389/fphar.2, 2023
2023 Hsieh YC, Pan MH, Jeng WJ, Hu HH, Liu J, Mizokami M, Chen CJ, (Yang HI*, Serum HBcrAg and hepatocellular carcinoma in a Taiwanese population seronegative for HBsAg and anti-HCV., CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, vol. 21(5), 1303-1313, 2023
2023 Hsu CC, Gopalakrishna H, Mironova M, Lee MH, Chen CJ, (Yang HI, Wiese M, Chang KM, Wright EC, Abijo T, Feld JJ, Kaplan DE, Risk of Hepatocellular Carcinoma After Spontaneous Clearance of Hepatitis C Virus and in Noncirrhosis Chronic Hepatitis C Patients With Sustained Virological Response: A Systematic Review., CLINICAL INFECTIOUS DISEASES, vol. 77(Suppl 3), S245-S256, 2023
2023 Lin HC, Liu J, Pan MH, Lee MH, Batrla-Utermann R, Lu SN, Jeng WJ, (Yang HI*, Chen CJ, Rapid decline rather than absolute level of HBsAg predicts its seroclearance in untreated chronic hepatitis B patients from Taiwanese communities., CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, vol. 14(8), e00586, 2023
2023 Chang GC, Chiu CH, Yu CJ, Chang YC, Chang YH, Hsu KH, Wu YC, Chen CY, Hsu HH, Wu MT, Yang CT, Chong IW, Lin YC, Hsia TC, Lin MC, Su WC, Lin CB, Lee KY, Wei YF, Lan GY, Chan WP, Wang KL, Wu MH, Tsai HH, Chian CF, Lai RS, Shih JY, Wang CL, Hsu JS, Chen KC, Chen CK, Hsia JY, Peng CK, Tang EK, Hsu CL, Chou TY, Shen WC, Tsai YH, Tsai CM, Chen YM, Lee YC, Chen HY, Yu SL, Chen CJ, Wan YL, Hsiung CA, Yang PC, Low-dose CT screening among never-smokers with or without a family history of lung cancer in Taiwan: a prospective cohort study., LANCET RESPIRATORY MEDICINE, vol. 29, S2213-2600(23)00338-7, 2023
2023 Razavi HA, Buti M, Terrault NA, Zeuzem S, Yurdaydin C, Tanaka J, Aghemo A, Akarca US, Al Masri NM, Alalwan AM, Aleman S, Alghamdi AS, Alghamdi S, Al-Hamoudi WK, Aljumah AA, Altraif IH, Asselah T, Ben-Ari Z, Berg T, Biondi MJ, Blach S, Braga WSM, Brandao-Mello CE, Brunetto MR, Cabezas J, Cheinquer H, Chen PJ, Cheon ME, Chuang WL, Coffin CS, Coppola N, Craxi A, Crespo J, De Ledinghen V, Duberg AS, Etzion O, Ferraz MLG, Ferreira PRA, Forns X, Foster GR, Gaeta GB, Gamkrelidze I, Garcia-Samaniego J, Gheorghe LS, Gholam PM, Gish RG, Glenn J, Hercun J, Hsu YC, Hu CC, Huang JF, Janjua N, Jia J, Kaberg M, Kaita KDE, Kamal H, Kao JH, Kondili LA, Lagging M, Lazaro P, Lazarus JV, Lee MH, Lim YS, Marotta PJ, Navas MC, Naveira MCM, Orrego M, Osiowy C, Pan CQ, Pessoa MG, Raimondo G, Ramji A, Razavi-Shearer DM, Razavi-Shearer K, Rios-Hincapie CY, Rodriguez M, Rosenberg WMC, Roulot DM, Ryder SD, Safadi R, Sanai FM, Santantonio TA, Sarrazin C, Shouval D, Tacke F, Tergast TL, Villalobos-Salcedo JM, Voeller AS, (Yang HI, Yu ML, Zuckerman E, Hepatitis D double reflex testing of all hepatitis B carriers in low-HBV- and high-HBV/HDV-prevalence countries., JOURNAL OF HEPATOLOGY, vol. 79(2), 576-580, 2023
2023 Chu YJ, (Yang HI, Hu HH, Liu J, Lin YL, Chang CL, Luo WS, Jen CL, Chen CJ, HBV genotype-dependent association of HLA variants with the serodecline of HBsAg in chronic hepatitis B patients., SCIENTIFIC REPORTS, vol. 13(1), 359, 2023
2023 Chen CY, Chen TT, Feng YA, Yu M, Lin SC, Longchamps RJ, Wang SH, Hsu YH, (Yang HI, Kuo PH, Daly MJ, Chen WJ, Huang H, Ge T, Lin YF, Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits., Cell Genomics, vol. 3(12), 100436, 2023
2023 Polaris Observatory Collaborators, Adjusted estimate of the prevalence of hepatitis delta virus in 25 countries and territories., JOURNAL OF HEPATOLOGY, vol. 27, S0168-8278(23)05285-6, 2023
2023 Wong YJ, Nguyen VH, (Yang HI, Li J, Le MH, Wu WJ, Han NX, Fong KY, Chen E, Wong C, Rui F, Xu X, Xue Q, Hu XY, Leow WQ, Goh GB, Cheung R, Wong G, Wong VW, Yu MW, Nguyen MH, Impact of fatty liver on long-term outcomes in chronic hepatitis B: a systematic review and matched analysis of individual patient data meta-analysis., CLINICAL AND MOLECULAR HEPATOLOGY, 2023
2023 Wu X, Xu X, Zhou J, Sun Y, Ding H, Xie W, Chen G, Ma A, Piao H, Wang B, Chen S, Meng T, Ou X, (Yang HI, Jia J, Kong Y, You H, HCC prediction model performance decrease with long-term antiviral therapy in chronic hepatitis B patients., CLINICAL AND MOLECULAR HEPATOLOGY, 2023
2023 Lin TW, Chang JK, Wu YR, Sun TH, Cheng YY, Ren CT, Pan MH, Wu JL, Chang KH, (Yang HI, Chen CM, Wu CY, Chen YR, Ganglioside-focused Glycan Array Reveals Abnormal Anti-GD1b Auto-antibody in Plasma of Preclinical Huntington's Disease., MOLECULAR NEUROBIOLOGY, 2023
2023 Lu TY, Wu CD, Huang YT, Chen YC, Chen CJ, (Yang HI, Pan WC, Exposure to PM(2.5) Metal Constituents and Liver Cancer Risk in REVEAL-HBV., JOURNAL OF EPIDEMIOLOGY, 2023
2023 Petrick JL, Florio AA, Zen J, Wang Y, Gewirtz AT, Pfeiffer RM, Loftus S, Inglefield J, Koshiol J, Yang B, Yu K, Hildesheim A, Chen CJ, (Yang HI, Lee MH, McGlynn KA, Biomarkers of gut barrier dysfunction and risk of hepatocellular carcinoma in the REVEAL-HBV and REVEAL-HCV cohort studies., INTERNATIONAL JOURNAL OF CANCER, 2023
2023 Lai YH*, Leung W, Chang PH, Zhou WX, (Wang YS*, Structural identification of carbohydrate isomers using ambient infrared-assisted dissociation., Analytica chimica acta, vol. 1264, 341307, 2023
2023 Lai Yin‐Hung*, (Wang Yi‐Sheng)*, Advances in high‐resolution mass spectrometry techniques for analysis of high mass‐to‐charge ions, Mass Spectrometry Reviews, vol. 42(6):2426-2445, 2023
2023 Yi-Hong Cai, Cheng-Huang Lin, Yi-Sheng Wang, Theoretical study of general principle of high-resolution MALDI-linear time-of-flight mass spectrometry in middle to high m/z ranges, INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, vol. 489, 117052, 117052, 2023
2023 Fu-Ting Hsiao, Hung-Jen Chien, Ya-Hsien Chou, Shih-Jung Peng, Mei-Hsin Chung, Tzu-Hui Huang, Li-Wen Lo, (Chia-Ning Shen, Hsiu-Pi Chang, Chih-Yuan Lee, Chien-Chia Chen, Yung-Ming Jeng, Yu-Wen Tien, Shiue-Cheng Tang*, Transparent tissue in solid state for solvent-free and antifade 3D imaging, Nature Communications, vol. 14(1), 3395, 2023
2023 WK Hua, JC Hsu, YC Chen, PS Chang, KLK Wen, PN Wang, WC Yang, (CN Shen, YS Yu, YC Chen, IC Cheng, SCY Wu, Quantum pBac: An effective, high-capacity piggyBac-based gene integration vector system for unlocking gene therapy potential, FASEB JOURNAL, vol. 37:, e23108, 2023
2023 Hu CM, Huang CC, Hsu MF, Chien HJ, Wu PJ, Chen YI, Jeng YM, Tang SC, Chung MH, (Shen CN, Chang MC, Chang YT, Tien YW, Lee WH, Oncogenic KRAS, Mucin 4, and Activin A-Mediated Fibroblast Activation Cooperate for Panin Initiation., Advanced Science, vol. 2023, e2301240, 2023
2023 Nguyen HTV, Chen X, Parada C, Luo AC, Shih O, Jeng US, Huang CY, Shih YL*, (Ma C*, Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome, Nature Communications, vol. 14(1), 1903, 2023
2023 Huang KA*, Chen X, Mohapatra A, Nguyen HTV, Schimanski L, Tan TK, Rijal P, Vester SK, Hills RA, Howarth M, Keeffe JR, Cohen AA, Kakutani LM, Wu YM, Shahed-Al-Mahmud M, Chou YC, Bjorkman PJ, Townsend AR, (Ma C)*, Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2., Nature communications, vol. 14(1), 311, 2023
2023 Wu CY, Kao SE, Tseng YC, Lin YP, Hou JT, Wu LY, Chiu S, (Ma CA, Hsiao PW, Hsiao J, Chen JR, Pilot-scale production of inactivated monoglycosylated split H(1)N(1) influenza virus vaccine provides cross-strain protection against influenza viruses., Antiviral research, vol. 216, 105640, 2023
2023 Chen WJ, Huang WK, Pather SR, Chang WF, Sung LY, Wu HC, Liao MY, Lee CC, Wu HH, Wu CY, Liao KS, Lin CY, Yang SC, Lin H, Lai PL, Ng CH, Hu CM, Chen IC, Chuang CH, Lai CY, Lin PY, Lee YC, Schuyler SC, Schambach A, Lu FL, (Lu J*, Podocalyxin-Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis Pathway., Advanced science (Weinheim, Baden-Wurttemberg, Germany), vol. 10(1), e2205451, 2023
2023 Wang, S.-W., Ko, Y.-A., Chen, C.-Y., Liao, K.-S., Chang, Y.-H., Lee, H.-Y., Yu, Y.-H., Lih, Y.-H., Cheng, Y.-Y., Lin, H.-H., Hsu, T.-L., Wu, C.-Y., (Lin, K.-I)*, Wong, C.-H.*, Mechanism of Antigen Presentation and Specificity of Antibody Cross-Reactivity Elicited by an Oligosaccharide-Conjugate Cancer Vaccine, Journal of the American Chemical Society, vol. 145(17), 9840-9849, 2023
2023 Yang, T.-T., Chiang, M.-F., Chang, C.-C., Yang, S.-Y., Huang, S.-W., Liao, N.-S., Shih, H.-M., Hsu, W., Lin, K.-I)*., SENP2 restrains the generation of pathogenic Th17 cells in mouse models of colitis, Communications Biology, vol. 6(1), 629, 2023
2023 Liu, Z., Wang, J., Shi, Y., Yee, B. A., Terrey, M., Zhang, Q., Lee, J.-C., (Lin, K.-I, Wang, H.-J. A., Ackerman, S., Yeo, G. W., Cui, H., Yang, X. L., Seryl-tRNA synthetase promotes translational readthrough by mRNA binding and involvement of the selenocysteine incorporation machinery, Nucleic Acids Research, vol. 51(19), 10768-10781, 2023
2023 H. T. Huang, I. W. Lo, Y. C. Lin, G. Y. Liao, Y. S. Lin, L. J. Zhang, T. L. Li, C. Ching Liaw*, Y. H. Kuo*, Kaguacidine A: a novel spirohydantoin-containing cucurbitane glycoside from vines of Momordica charantia, NATURAL PRODUCT RESEARCH, vol. 38(13):2179-2186, 2023
2023 Y. L. Wang, C. Y. Chang, N. S. Hsu, I. W. Lo, K. H. Lin, C. L. Chen, C. F. Chang, Z. C. Wang, Y. Ogasawara, T. Dairi, C. Maruyama, Y. Hamano*, T. L. Li*, N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry, NATURE COMMUNICATIONS, vol. 14:2528, 1-14, 2023
2023 S. S. Chang, H. T. Huang, W. C. Wei, I. W. Lo, Y. C. Lin, C. H. Chao, G. Y. Liao, Y. C. Shen, J. J. Chen, T. L. Li, L. T. Lin, C. J. Tai, Y. H. Kuo, C. C. Liaw*, Anti-inflammatory Effect of Euphane-and Tirucallane-type Triterpenes Isolated from Traditional Herb Euphorbia neriifolia L, FRONTIERS IN CHEMISTRY, vol. 11, 1-13, 10.3389/fchem.2023.1, 2023
2023 S. H. Liu, H. T. Huang, I. W. Lo, Y. C. Lin, G. Y. Liao, C. H. Chao, H. C. Huang, F. R. Chang, T. L. Li, Y. C. Shen, C. C. Liao*, Potential natural product 3,4-seco-schitriterpenoids from Kadsura japonica L. as anti-neuroinflammatory agents, BIOORGANIC CHEMISTRY, vol. 141, 106843, 2023
2023 Wang C.-K., Chen T.-J., Tan G.Y.T., Chang F.-P., Sridharan S., Yu C.-H. A., Chang Y.-H., Chen Y.-J., Cheng L.-T., (Hwang-Verslues W.W.)*, MEX3A mediates p53 degradation to suppress ferroptosis and facilitate ovarian cancer tumorigenesis, Cancer Research, vol. 83 (2), 251-263, 2023
2023 Cheng L.-T., Tan G.Y.T., Chang F.-P., Wang C.-K., Chou Y.-C., Hsu P.-H., (Hwang-Verslues W.W.)*, Core clock gene BMAL1 and RNA-binding protein MEX3A collaboratively regulate Lgr5 expression in intestinal crypt cells, SCIENTIFIC REPORTS, vol. 13, 17597, 2023
2023 Chen Wei‐Ju, Huang Wei‐Kai, Pather Sarshan R., Chang Wei‐Fang, Sung Li‐Ying, Wu Han‐Chung, Liao Mei‐Ying, Lee Chi‐Chiu, Wu Hsuan‐Hui, Wu Chung‐Yi, Liao Kuo‐Shiang, Lin Chun‐Yu, Yang Shang‐Chih, Lin Hsuan, Lai Pei‐Lun, Ng Chi‐Hou, Hu Chun‐Mei, Chen I‐Chih, Chuang Chi‐Hsuan, Lai Chien‐Ying, Lin Po‐Yu, Lee Yueh‐Chang, Schuyler Scott C., Schambach Axel, Lu Frank Leigh, Lu Jean, Podocalyxin‐Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis Pathway, Advanced Science, vol. 10(1), 2205451, 2023
2023 Chang YT*, Peng HY, (Hu CM, Tien SC, Chen YI, Jeng YM, Chang MC, Pancreatic cancer-derived small extracellular vesical ezrin activates fibroblasts to exacerbate cancer metastasis through STAT3 and YAP-1 signaling pathways., Molecular Oncology, vol. 17, 1628-1647, 2023
2023 Hu CM)*, Huang CC, Hsu MF, Chien HJ, Wu PJ, Chen YI, Jeng YM, Tang SC, Chung MH, Shen CN, Chang MC, Chang YT, Tien YW, Lee WH*, Oncogenic KRAS, Mucin 4, and Activin A-Mediated Fibroblast Activation Cooperate for PanIN Initiation, Advanced Science (Weinheim, Baden-Wurttemberg, Germany), vol. 2301240, 1-20, 2023
2023 Nguan HS, Tsai ST, Liew CY, Reddy NS, (Hung SC, Ni CK*, The collision-induced dissociation mechanism of sodiated Hex-HexNAc disaccharides., Physical chemistry chemical physics : PCCP, vol. 25(33), 22179-22194, 2023
2023 Jing-Ping Wang, Chun-Hao Hung, Yao-Huei Liou, Ching-Chen Liu, Kun-Hai Yeh, Keh-Yang Wang, Zheng-Sheng Lai, Tzu-Chi Hsu, Tung-Liang Lee, Yu-Chiau Shyu, Pei-Wen Hsiao, Liuh-Yow Chen, (Trees-Juen Chuang, Chen-Hsin Albert Yu, Nah-Shih Liao, Che-Kun James Shen*, Long-term hematopoietic transfer of the anti-cancer and lifespan-extending capabilities of a genetically engineered blood system by transplantation of bone marrow mononuclear cells, eLife, vol. 12, RP88275, 2023
2023 Trees-Juen Chuang*, Tai-Wei Chiang, Chia-Ying Chen, Assessing the impacts of various factors on circular RNA reliability, LIFE SCIENCE ALLIANCE, vol. 6(5), e202201793, 2023
2023 Marieke Vromman, Jasper Anckaert, Stefania Bortoluzzi, Alessia Buratin, Chia-Ying Chen, Qinjie Chu, (Trees-Juen Chuang, Roozbeh Dehghannasiri, Christoph Dieterich, Xin Dong, Paul Flicek, Enrico Gaffo, Wanjun Gu, Chunjiang He, Steve Hoffmann, Osagie Izuogu, Michael S. Jackson, Tobias Jakobi, Eric C. Lai, Justine Nuytens, Julia Salzman, Mauro Santibanez-Koref, Peter Stadler, Olivier Thas, Eveline Vanden Eynde, Kimberly Verniers, Guoxia Wen, Jakub Westholm, Li Yang, Chu-Yu Ye, Nurten Yigit, Guo-Hua Yuan, Jinyang Zhang, Fangqing Zhao, Jo Vandesompele, Pieter-Jan Volders, Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision., NATURE METHODS, vol. 20, 1159-1169 (impact factor: 48.0; Rank: 1/77), 2023
2023 Yu-Chen Chen, Chia-Ying Chen, Tai-Wei Chiang, Ming-Hsien Chan, Michael Hsiao, Huei-Mien Ke, Isheng Jason Tsai, Trees-Juen Chuang*, Detecting intragenic trans-splicing events from non-co-linearly spliced junctions by hybrid sequencing, NUCLEIC ACIDS RESEARCH, vol. 51(15), 7777-7797 (SCI impact factor: 16.6; Rank (BIOCHEMISTRY & MOLECULAR BIOLOGY): 6/313), 2023
2023 Li Huang-Yi, Lee Ni-Chung, Chiu Yu-Ting, Chang Yu-Wen, Lin Chu-Chung, Chou Cheng-Li, Chien Yin-Hsiu, Hwu Wuh-Liang, Cheng Wei-Chieh, Harnessing polyhydroxylated pyrrolidines as a stabilizer of acid alpha-glucosidase (GAA) to enhance the efficacy of enzyme replacement therapy in Pompe disease, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 78, 117129, 2023
2023 Lin Hung-Yi, Chang Shih-Ying, Teng Hsuan-Hsuan, Wu Hsi-Ju, Li Huang-Yi, Cheng Chia-Chun, Chuang Chih-Kuang, Lin Hsiang-Yu, Lin Shuan-Pei, Cheng Wei-Chieh, Discovery of small-molecule protein stabilizers toward exogenous alpha-l-iduronidase to reduce the accumulated heparan sulfate in mucopolysaccharidosis type I cells, European Journal of Medicinal Chemistry, vol. 247, 115005, 2023
2023 Tien-Wei Lin, Jung-Kai Chang, Yih-Ru Wu, Tsung-Hsien Sun, Yang-Yu Cheng, Chien-Tai Ren, Mei-Hung Pan, Jin-Lin Wu, Kuo-Hsuan Chang, Hwai-I Yang, Chiung-Mei Chen*, Chung-Yi Wu*, Yun-Ru Chen)*, Ganglioside-focused Glycan Array Reveals Abnormal Anti-GD1b Auto-antibody in Plasma of Preclinical Huntington’s Disease, MOLECULAR NEUROBIOLOGY, vol. 60(7), 3873-3882, 2023
2023 Tien-Ying Tsai§, Chun-Yu Chen§, Tien-Wei Lin, Tien-Chang Lin, Feng-Lan Chiu, Orion Shih, Ming-Yun Chang, Yu-Chun Lin, An-Chung Su, U-Ser Jeng, Hung-Chih Kuo, Chi-Fon Chang, Yun-Ru Chen)*, Amyloid Modifier SERF1a Interacts with PolyQ-expanded Huntingtin Exon 1 via Helical Interactions and Exacerbates PolyQ-induced Toxicity, Communications Biology, vol. 6, 767, 2023
2023 Yichu Nie(#, Wei Chen(#, Yong Kang(#, Xue Yuan, Yongjiang Li, Jun Zhou, Wei Tao*, Xiaoyuan Ji*, (#: Co-first author, equal contribution, Two-dimensional porous vermiculite-based nanocatalysts for synergetic catalytic therapy, Biomaterials, vol. 295, 122031, 2023
2023 Jiang Ouyang, Zhongyang Zhang, Bo Deng, Jinggong Liu, Liqiang Wang, Haijun Liu, Seyoung Koo, Shuying Chen, Yongjiang Li, Alexey V. Yaremenko, Xiangang Huang, Wei Chen, Yuhan Lee, Wei Tao*, Oral drug delivery platforms for biomedical applications, Materials Today, vol. 62, 296-326, 2023
2023 Liu Yu(#, Mian Yu(#, Wei Chen(#, Shengjie Sun, Wenxin Huang, Tianqi Wang, Zhangwen Peng, Zewen Luo, Yixuan Fang, Yongjiang Li, Yang Deng, * Meiying Wu, * Wei Tao*, (#: Co-first author, equal contribution, In situ separable nanovaccines with stealthy bioadhesive capability for durable cancer immunotherapy, Journal of the American Chemical Society, vol. 145, 8375-8388, 2023
2023 Jiang Ouyang, Bo Deng, Binhua Zou, Yongjiang Li, Qingyue Bu, Yuan Tian, Mingkai Chen, Wei Chen, Na Kong, Tianfeng Chen*, Wei Tao*, Oral hydrogel microbeads-mediated in situ synthesis of selenoproteins for regulating intestinal immunity and microbiota, Journal of the American Chemical Society, vol. 145, 12193-12205, 2023
2023 Wei Chen, Yongjiang Li, Chuang Liu, Yong Kang, Duotian Qin, Shuying Chen, Jun Zhou, Hai-Jun Liu, Bijan Emiliano Ferdows, Dylan Neal Patel, Xiangang Huang, Seyoung Koo, Na Kong, Xiaoyuan Ji, Yihai Cao, Wei Tao*, Tian Xie*, In situ Engineering of Tumor-Associated Macrophages via a Nanodrug-Delivering-Drug (β-Elemene@Stanene) Strategy for Enhanced Cancer Chemo-Immunotherapy., Angewandte Chemie International Edition, vol. 62, e202308413, 2023