Language

化學生物學研究領域 2014

Cheng, Wei-Chieh

  • Tseng YY, Liou JM, Hsu TL, Cheng WC, Wu MS, Wong CH, 2014, “Development of bacterial transglycosylase inhibitors as new antibiotics: moenomycin A treatment for drug-resistant Helicobacter pylori.”, Bioorganic & medicinal chemistry letters, 24(11), 2412-2414. (SCIE)
  • Huang LY, Huang SH, Chang YC, Cheng WC, Cheng TJ, Wong CH, 2014, “Enzymatic Synthesis of Lipid II and Analogues.”, Angewandte Chemie-International Edition, 53(31), 8060-8065. (SCIE)
  • Hsu CH, Schelwies M, Enck S, Huang LY, Huang SH, Chang YF, Cheng TJ, Cheng WC, Wong CH, 2014, “Iminosugar C-Glycoside Analogues of alpha-d-GlcNAc-1-Phosphate: Synthesis and Bacterial Transglycosylase Inhibition.”, The Journal of organic chemistry, 79(18), 8629-8637. (SCIE)

Hung, Shang-Cheng

  • Ko YC; Tsai CF; Wang CC; Dhurandhare VM; Hu PL; Su TY; Lico LS; Zulueta MM; Hung SC., 2014, “Microwave-assisted one-pot synthesis of 1,6-anhydrosugars and orthogonally protected thioglycosides.”, J Am Chem Soc., 136, 14425-14431. (SCIE)
  • Chang CH; Lico LS; Huang TY; Lin SY; Chang CL; Arco SD; Hung SC., 2014, “Synthesis of the heparin-based anticoagulant drug Fondaparinux.”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53, 9876-9879. (SCIE)
  • Li YC; Ho IH; Ku CC; Zhong YQ; Hu YP; Chen ZG; Chen CY; Lin WC; Zulueta MM; Hung SC; Lin MG; Wang CC; Hsiao CD., 2014, “Interactions That Influence the Binding of Synthetic Heparan Sulfate Based Disaccharides to Fibroblast Growth Factor-2”, ACS Chem Biol., 9, 1912-1717. (SCIE)
  • Hsu Y; Ma HH; Lico LS; Jan JT; Fukase K; Uchinashi Y; Zulueta MM; Hung SC., 2014, “One-pot synthesis of N-acetyl- and N-glycolylneuraminic acid capped trisaccharides and evaluation of their influenza A(H1N1) inhibition.”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53, 2413-2416. (SCIE)
  • Patil, P. S.; Zulueta, M. M. L.; Hung, S.-C., 2014, “Synthesis of Phosphatidylinositol Mannosides”, Journal of the Chinese Chemical Society, 61, 151-162. (SCIE)
  • Huang, T.-Y.; Zulueta, M. M. L.; Hung, S.-C., 2014, “Regioselective One-pot Protection, Protection-Glycosylation and Protection- Glycosylation-Glycosylation of Carbohydrates: A Case Study with D-Glucose”, Organic & Biomolecular Chemistry, 12(2), 376-382. (SCIE)

Juan, Li-Jung

  • Chu CS, Lo PW, Yeh YH, Hsu PH, Peng SH, Teng YC, Kang ML, Wong CH, Juan LJ, 2014, “O-GlcNAcylation regulates EZH2 protein stability and function.”, Proceedings of the National Academy of Sciences of the United States of America, 111(4), 1355-60. (SCIE)

Li, Tsung-Lin

  • S. Y. Lyu, Y. C. Liu, C. Y. Chang, C. J. Huang, Y. H. Chiu, C. M. Huang, N. S. Hsu, K. H. Lin, C. J. Wu, M. D. Tsai, T. L. Li*, 2014, “Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics effectively killing vancomycin-resistant Enterococcus”, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(31), 10989-10995. (SCIE)
  • X. W. Zou, Y. C. Liu, N. S. Hsu, C. J. Huang, S. Y. Lyu, H. C. Chan, C. Y. Chang, H. W. Yeh, K. H. Lin, C. J. Wu, M. D. Tsai, T. L. Li*, 2014, “Structure and mechanism of a non-heme iron-SAM dependent C-methyltransferase and its engineering to hydratase and O-methyltransferase”, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 70(6), 1549-1560.
  • K. C. Wang, S. Y. Lyu, Y. C. Liu, C. Y. Chang, C. J. Wu, T. L. Li*, 2014, “Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple-reaction complexes”, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 70(5), 1401-1410.
  • C. Y. Chang, S. Y. Lyu, Y. C. Liu, N. S. Hsu, C. C. Wu, C. F. Tang, K. H. Lin, J. Y. Ho, C. J. Wu, M. D. Tsai, T. L. Li*, 2014, “Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53(7), 1943-1948. (SCIE)

Liang, Chi-Ming

  • Ho, M. Y., Hung S. W., Liang, C. M.*, Liang, S. M. , 2014, “Recombinant viral capsid protein VP1 suppresses lung cancer metastasis by inhibiting COX-2/PGE2 and MIG-7 ”, Oncotarget, 5(11), 3931-3943.

Ma, Che Alex

  • Huang CK, Yang CY, Jeng YM, Chen CL, Wu HH, Chang YC, Ma C, Kuo WH, Chang KJ, Shew JY, Lee WH, 2014, “Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-kappaB-mediated antiapoptotic pathway.”, Oncogene, 33, 2968-2977. (SCIE)
  • Chen PC, Chuang PK, Chen CH, Chan YT, Chen JR, Lin SW, Ma C, Hsu TL, Wong CH, 2014, “Role of N-linked glycans in the interactions of recombinant HCV envelope glycoproteins with cellular receptors.”, ACS chemical biology, 9(7), 1437-1443. (SCIE)
  • Kung CC, Naik MT, Wang SH, Shih HM, Chang CC, Lin LY, Chen CL, Ma C, Chang CF, Huang TH, 2014, “Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain.”, The Biochemical journal, 462(1), 53-65. (SCIE)
  • Chen JR, Yu YH, Tseng YC, Chiang WL, Chiang MF, Ko YA, Chiu YK, Ma HH, Wu CY, Jan JT, Lin KI*, Ma C*, Wong CH*, 2014, “Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections.”, Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2476-2481. (SCIE)

Wong, Chi-Huey

  • J -R. Huang , Y.-C. Tsia , Y.-J. Chang , J.-C. Wu , J.-T. Hung , K.-H. Lin , C.-H. Wong and Alice L. Yu, 2014, “alpha-Galactosylceramide but Not Phenyl-Glycolipids Induced NKT Cell Anergy and IL-33-Mediated Myeloid-Derived Suppressor Cell Accumulation via Upregulation of egr2/3.”, Journal of immunology, 192(4), 1972-1981. (SCIE)
  • J.-J. Shie, Y.-C. Liu, Y.−M. Lee, C. Lim, J.-M. Fang, C.-H. Wong, 2014, “An azido-BODIPY probe for glycosylation: initiation of strong fluorescence upon triazole formation”, Journal of the American Chemical Society, 136(28), 9953-9961. (SCIE)
  • Chung-Yi Wu, Chi-Huey Wong, 2014, “Automated programmable one-pot synthesis of glycans”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 45-52, Japan: Springer Japan.
  • Chung-Yi Wu, Chi-Huey Wong, 2014, “Automation in glycan synthesis”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 345-351, Japan: Springer Japan.
  • E. Falkowska, A. Ramos, K. J. Doores, J. H. Lee, C. Blattner, A. Ramirez, R. Derking, M. J. van Gils, C.-H. Liang, R. Mcbride, S. S. Shivatare, C.-Y. Wu, P.-Y. Chan-Hui, Y. Liu, T. Feizi, M. B. Zwick, W. C. Koff, M. S. Seaman, K. Swiderek, J. P. Moore, J. C. Paulson, C.-H. Wong, A. B. Ward, I. A. Wilson, R. W. Sanders, P. Poignard, and D. R. Burton, 2014, “Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers.”, Immunity, 40(5), 657-668. (SCIE)
  • A.-K. Sauer, C.-H. Liang, J. Stech, B. Peeters, P. Quéré, C. Schwegmann-Wessels, C.-Y. Wu, C.-H. Wong, G. Herrler , 2014, “Characterization of the sialic Acid binding activity of influenza a viruses using soluble variants of the h7 and h9 hemagglutinins.”, PloS one, 9(2), e89529. (SCIE)
  • J.-M. Fang, Y.-S. Chen, H.-M. Yu, J.-J. Shie, T.-J. R. Cheng, C.-Y. Wu, C.-H. Wong, 2014, “Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity.”, Bioorganic & medicinal chemistry, 22(5), 1766-1772. (SCIE)
  • Chi-Huey Wong, 2014, “Chemo-enzymatic Synthesis of Glycans: Overview”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 293-294, Japan: Springer Japan.
  • Chi-Huey Wong and Naoyuki Taniguchi, 2014, “Current Status and New Challenges”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 11-14, Japan: Springer Japan.
  • Y.-Y. Tseng, J.-M. Liou, T.-L. Hsu, W.-C. Cheng, M.-S. Wu, C.-H. Wong, 2014, “Development of bacterial transglycosylase inhibitors as new antibiotics: Moenomycin A treatment for drug-resistant Helicobacter pylori.”, Bioorganic & medicinal chemistry letters, 24(11), 2412-2414. (SCIE)
  • L.-Y. Huang, S.-H. Huang, Y.-C. Chang, W.-C. Cheng, T.-J. R. Cheng, and C.-H. Wong, 2014, “Enzymatic Synthesis of Lipid II and Analogues.”, Angewandte Chemie-International Edition, 53(31), 8060-8065. (SCIE)
  • S.-C. Lin, W.-C. Liu, J.-T. Jan, C.-H. Wong, S.-C. Wu, 2014, “Glycan Masking of Hemagglutinin for Adenovirus Vector and Recombinant Protein Immunizations Elicits Broadly Neutralizing Antibodies against H5N1 Avian Influenza Viruses”, PLoS One, 9(3), e92822. (SCIE)
  • Chi-Huey Wong, 2014, “Homogeneous Glycoproteins: Overview”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 959-962, Japan: Springer Japan.
  • Chung-Yi Wu, Chi-Huey Wong, 2014, “Imaging by Click Chemistry”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 459-465, Japan: Springer Japan.
  • C.-H. Hsu, M. Schelwies, S. Enck, L.-Y. Huang, S.-H. Huang, Y.-F. Chang, T.-J. Cheng, W.-C. Cheng, C.-H. Wong, 2014, “Iminosugar C-Glycoside Analogues of alpha-d-GlcNAc-1-Phosphate: Synthesis and Bacterial Transglycosylase Inhibition.”, The Journal of organic chemistry, 79(18), 8629-8637. (SCIE)
  • H.-Y. Lee, C.-Y. Chen, T.-I. Tsai, S.-T. Li, K.-H. Lin, Y.-Y. Cheng, C.-T. Ren, T.-J. Cheng, C.-Y. Wu, C.-H. Wong, 2014, “Immunogenicity study of Globo H derivatives with modification at the reducing or non-reducing end of the tumor antigen”, J. Am. Chem. Soc., 136(48), 16844-16853. (SCIE)
  • Tsung-I Tsai, Chung-Yi Wu, Chi-Huey Wong, 2014, “Large-scale enzymatic synthesis of glycans with cofactor regeneration”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 409-417, Japan: Springer Japan.
  • Chi-Huey Wong, 2014, “Molecular Probes for Glycosylation: Overview”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 455-457, Japan: Springer Japan.
  • C.-S. Chu, P.-W. Lo, Y.-H. Yeh, P.-H. Hsu, S.-H. Peng, Y.-C. Teng, M.-L. Kang, C.-H. Wong and L.-J. Juan, 2014, “O-GlcNAcylation regulates EZH2 protein stability and function.”, Proceedings of the National Academy of Sciences of the United States of America, 111(4), 1355-1360. (SCIE)
  • B.-T. Hong, C.-L. Chen, Jim-Min Fang, Shi-Yun Wang, Wen-I Huang, Yih-Shyun E. Cheng, and Chi-Huey Wong, 2014, “Oseltamivir Hydroxamate and Acyl Sulfonamide Derivatives as Influenza Neuraminidase Inhibitors”, BIOORGANIC & MEDICINAL CHEMISTRY, 22(23), 6647-6654. (SCIE)
  • J.-T. Hung, Y.-C. Tsai, W.-D. Lin, J.-T. Jan, K.-H. Lin, J.-R. Huang, J.-Y. Cheng, M.-W. Chen, C.-H. Wong, and A. L. Yu, 2014, “Potent adjuvant effects of novel NKT stimulatory glycolipids on hemagglutinin based DNA vaccine for H5N1 influenza virus.”, Antiviral research, 107, 110-118. (SCIE)
  • Chung-Yi Wu, Chi-Huey Wong, 2014, “Preparation of glycan array and its applications”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 35-43, Japan: Springer Japan.
  • P.-C. Chen, P.-K. Chuang, C.-H. Chen, J.-R. Chen, S.-W. Lin, C. Ma, T.-L. Hsu, C.-H. Wong, 2014, “Role of N-linked glycans in the interactions of recombinant HCV envelope glycoproteins with cellular receptors.”, ACS chemical biology, 9(7), 1437-1443. (SCIE)
  • C.-Y. Wang, C.-Y. Wu, T.-J. Hung, C.-H. Wong, C.-H. Chen, 2014, “Sequence-constructive SELEX: A new strategy for screening DNA aptamer binding to Globo H.”, Biochemical and biophysical research communications, 452(3), 484-489. (SCIE)
  • Y.-W. Lou, P.-Y. Wang, S.-C. Yeh, P.-K. Chuang, S.-T. Li, C.-Y. Wu, K.-H. Khoo, M. Hsiao, T.-L. Hsu, C.-H. Wong, 2014, “Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers”, Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2482-2487. (SCIE)
  • C.-L. Chen, T.-C. Lin, S.-Y. Wang, J.-J. Shie, K.-C. Tsai, Y.-S. E. Cheng, J.-T. Jan, C.-J. Lin, J.-M. Fang, and C.-H. Wong, 2014, “Tamiphosphor Monoesters as Effective Anti-influenza Agents”, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 81, 106-118. (SCIE)
  • J. Lin, Y.-J. Chang, W.-B. Yang, A. L. Yu, and C.-H. Wong, 2014, “The Multifaceted Effects of Polysaccharides Isolated from Dendrobium huoshanense on Immune Functions with the Induction of Interleukin-1 Receptor Antagonist (IL-1ra) in Monocytes.”, PloS one, 9(4), e94040. (SCIE)
  • J.-R. Chen, Y.-H. Yu, Y.-C. Tseng, W.-L. Chiang, M.-F. Chiang, Y.-A. Ko, Y.-K. Chiu, S.-H. Ma, C.-Y. Wu, J.-T. Jan, K.-I. Lin, C. Ma and C.-H. Wong, 2014, “Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections”, Proceedings of the National Academy of Sciences of the United States of America, 111(7), 2476-2481. (SCIE)
  • Chung-Yi Wu, Chi-Huey Wong, 2014, “Vaccines”, editor(s): N. Taniguchi, T. Endo, G. W. Hart, P. H. Seeberger, C.-H.Wong, Glycoscience: Biology and Medicine, pp. 1529-1508, Japan: Springer Japan.

Wu, Chung-Yi

  • Lee, H.-Y., Chen, C.-Y., Tsai, T.-I., Li, S.-T., Lin, K.-H., Cheng, Y.-Y., Ren, C.-T., Cheng, T.-J., Wu, C.-Y.*, Wong, C.-H.* , 2014, “Immunogenicity study of Globo H derivatives with modification at the reducing or non-reducing end of the tumor antigen”, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136, 16844-16853. (SCIE)
  • Wu, C.-S., Lee, T.-Y., Chou, R.-H., Yen, C.-J., Huang, W.-C., Wu, C.-Y., Yu, Y.-L., 2014, “Development of a Highly Sensitive Glycan Microarray for Quantifying AFP-L3 for Early Prediction of Hepatitis B Virus-Related Hepatocellular Carcinoma.”, PLoS One, 9, e99959. (SCIE)
  • Wang, C.-Y., Wu, C.-Y., Hung, T.-J., Wong, C.-H., Chen, C.-H.* , 2014, “Sequence-Constructive SELEX: A New Strategy for Screening DNA Aptamer Binding to Globo H”, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 452, 484-489. (SCIE)
  • Chen-Shiou Wu, Chia-Jui Yen, Ruey-Hwang Chou, Chung-Yi Wu*, Yung-Luen Yu*, 2014, “Downregulation of MicroRNA-15b by Hepatitis B Virus X Enhances Hepatocellular Carcinoma Proliferation via Fucosyltransferase 2-Induced Globo H Expression”, INTERNATIONAL JOURNAL OF CANCER, 134(7), 1638-1647. (SCIE)
  • Y.-S. Chen, H.-M. Yu, J.-J. Shie, T.-J. R Cheng, C.-Y. Wu,* J.-M. Fang,*C.-H. Wong*, 2014, “Chemical Constituents of Plectranthus amboinicus and the Synthetic Analogs Possessing Anti-inflammatory Activity”, BIOORGANIC & MEDICINAL CHEMISTRY, 22(5), 1766-1772. (SCIE)
  • A.-K. Sauer, C.-H. Liang, J. Stech, B. Peeters, P. Quéré, C. Schwegmann-Wessels,C.-Y. Wu, C.-H., 2014, “Characterization of the Sialic Acid Binding Activity of Influenza A Viruses Using Soluble Variants of the H7 and H9 Hemagglutinins”, PLoS One, 9(2), e89529. (SCIE)
  • Lou,Y.-W., Wang, P.-Y., Yeh, S.-C., Chuang, P.-K., Li, S.-T., Wu, C.-Y., Khoo, K.-H., Hsiao, M., Hsu, T.-L., Wong, C.-H.* , 2014, “Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111, 2482-2487. (SCIE)
  • Juine-Ruey Che, 2014, “Vaccination of Monoglycosylated Hemagglutinin Induces Cross-Strain Protection against Influenza Virus Infections”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(7), 2476-2481. (SCIE)

Yang, An-Suei

  • Hung-Pin Peng, Kuo Hao Lee, Jhih-Wei Jian, An-Suei Yang*, 2014, “Origins of specificity and affinity in antibody-protein interactions”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(26), E2656-E2665. (SCIE)
  • Rajasekaran Mahalingama*, Hung-Pin Peng, An-Suei Yang*, 2014, “Prediction of fatty acid-binding residues on protein surfaces with three-dimensional probability distributions of interacting atoms”, BIOPHYSICAL CHEMISTRY, 192, 10-19. (SCIE)
  • Rajasekaran Mahalingam*, Hung-Pin Peng, An-Suei Yang*, 2014, “Prediction of FMN-binding residues with three-dimensional probability distributions of interacting atoms on protein surfaces”, JOURNAL OF THEORETICAL BIOLOGY, 343, 154-161. (SCIE)
  • Hsu, H.-J., K. H. Lee, J.-W. Jian, H.-J. Chang, C.-M. Yu, Y.-C. Lee, I.-C. Chen, H.-P. Peng, C. Y. Wu, Y.-F. Huang, C.-Y. Shao, K. P. Chiu and A.-S. Yang*, 2014, “Antibody variable domain interface and framework sequence requirements for stability and function by high throughput experiments.”, STRUCTURE, 22(1), 22-34. (SCIE)
  • Chang, H.-J., J.-W. Jian, H.-J. Hsu, Y.-C. Lee, H.-S. Chen, J.-J. You, S.-C. Hou, C.-Y. Shao, Y.-J. Chen, K.-P. Chiu, H.-P. Peng, K. H. Lee and A.-S. Yang*, 2014, “Loop sequence features and stability determinants in antibody variable domains by high throughput experiments.”, STRUCTURE, 22(1), 9-21. (SCIE)
  • Chang, H.-J. and A.-S. Yang*, 2014, “Design of Phage-Displayed Cystine-Stabilized Mini-Protein Libraries for Proteinaceous Binder Engineering”, Methods in Molecular Biology, 1088, 1-17.
  • Hsu, H.-J. and A.-S. Yang*, 2014, “Substrate Phage Display for Protease Substrate Sequence Characterization: Bovine Factor Xa as a Model System”, Methods in Molecular Biology, 1088, 107-124.

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