具代表性研究發表

搜尋類別: 關鍵字搜尋: Clear
年度 論文名稱
2017 Wang CK, Yang SC, Hsu SC, Chang FP, Lin YT, Chen SF, Cheng CL, Hsiao M, Lu FL, (Lu J)*, CHAC2 is essential for self-renewal and glutathione maintenance in human embryonic stem cells., Free radical biology & medicine, vol. 113, 439-451, 2017
2017 Lin Shan-Meng, (Lin Su-Chang, Hong Jhen-Yi, Su Tsung-Wei, Kuo Bai-Jiun, Chang Wei-Hsin, Tu Yi-Fan, Lo Yu-Chih*, Structural Insights into Linear Tri-ubiquitin Recognition by A20-Binding Inhibitor of NF-κB, ABIN-2, STRUCTURE, vol. 25(1), 66-78, 2017
2017 Tsung-Wei Su, Chao-Yu Yang, Wen-Pin Kao, Bai-Jiun Kuo, Shan-Meng Lin, Jung-Yaw Lin, Yu-Chih Lo*, (Su-Chang Lin)*, Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome, STRUCTURE, vol. 25(3), 407-420, 2017
2017 Lai, C.-Y., Su, Y.-W., (Lin, K.-I, Hsu, L.-C., Chuang, T.-H., Natural modulators of endosomal Toll-like receptor-mediated psoriatic skin inflammation, Journal of Immunology Research, vol. 10.1155/2017, 7807313, 2017
2017 Wu, J.-L., Chiang, M.-F., Hsu, P.-H., Tsai, D.-Y., Hung, K.-H., Wang, Y.-H., Angata, T.*, Lin, K.-I)*, O-GlcNAcylation is required for B cell homeostasis and antibody responses, NATURE COMMUNICATIONS, vol. 8(1):1854, 2017
2017 Y. W. Chen, C. H. Lee, Y. L. Wang, T. L. Li, H. C. Chang*, Nanodiamonds as nucleating agents for protein crystallization, LANGMUIR, vol. 33(26), 6521-6527, 2017
2017 Lee CC, Peng SH, Shen L, Lee CF, Du TH, Kang ML, Xu GL, Upadhyay AK, Cheng X, Yan YT, Zhang Y*, (Juan LJ)*, The Role of N-alpha-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting., Molecular Cell, vol. 68(1), 89-103.e7, 2017
2017 Huang S.-C., Wei P.-C., (Hwang-Verslues W.W., Kuo W.-H., Jeng Y.-M., Hu C.-H., Shew J.-Y., Huang C.-S., Chang K.-J., Lee E. Y.-H. P., Lee W.-H.*, TGF-β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB, EMBO MOLECULAR MEDICINE, vol. 9(12), 1660-1680, 2017
2017 Huang CK, Chang PH, Kuo WH, Chen CL, Jeng YM, Chang KJ, Shew JY, Hu CM, Lee WH., Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate., nature communications, vol. 8, 14706, 2017
2017 Huang SC, Wei PC, Hwang-Verslues WW, Kuo WH, Jeng YM, Hu CM, Shew JY, Huang CS, Chang KJ, Lee EY, Lee WH, TGF-β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB., EMBO molecular medicine, vol. 9, 1660-1680, 2017
2017 Padiyar, L. T.; Zulueta, M. M. L.; Sabbavarapu, N. M.; (Hung, S.-C.*, Yb(OTf)3-Catalyzed Desymmetrization of myo-Inositol-1,3,5-Orthoformate and Its Application in the Synthesis of Chiral Inositol Phosphates, J. Org. Chem, vol. 82, 11418-11430, 2017
2017 Tsai, C.-T.; Zulueta, M. M. L.; (Hung, S.-C.*, Synthetic Heparin and Heparan Sulfate: Probes in Defining Biological Functions, Curr. Opin. Chem. Biol., vol. 21, 152-159, 2017
2017 Huang, T.-Y.; Irene, D.; Ku, C.-C.; Zulueta, M. M. L.; Tai, T.-J.; Lain, S.-H.; Cheng, C.-P.; Tsai, P.-X.; Lin, S.-Y.; Chen, Z.-G.; Hsiao, C.-D.; Chyan, C.-L.*; (Hung, S.-C.*, Structure of the Complex between a Heparan Sulfate Octasaccharide and Mycobacterial Heparin-Binding Hemagglutinin, Angew. Chem. Int. Ed, vol. 56, 4192-4196, 2017
2017 Ho, K.-M.; Zulueta, M. M. L.; (Hung, S.-C.*, Stereoselective One-pot Synthesis of Polypropionates, Nat. Commun, vol. 8, 679, 2017
2017 Hughes, A. J.; Meneghetti, M. C. Z.; Huang, T.-Y.; (Hung, S.-C.); Elli, S.; Guerrini, M.; Rudd, T. R.; Lima, M. A.*; Yates, E. A.*, Investigating the Relationship between Temperature, Conformation and Calcium Binding in Heparin Model Oligosaccharides, Carbohydr. Res, vol. 438, 58-64, 2017
2017 Zheng RB, Jegouzo SAF, Joe M, Bai Y, Tran HA, Shen K, Saupe J, Xia L, Ahmed MF, Liu YH, Patil PS, Tripathi A, (Hung SC, Taylor ME, Lowary TL, Drickamer K, Insights into Interactions of Mycobacteria with the Host Innate Immune System from a Novel Array of Synthetic Mycobacterial Glycans., ACS chemical biology, vol. 12(12), 2990-3002, 2017
2017 Prados-Rosales, R.*; Carreño L.; Weinrick, B.; Lowary, T.; Baena, A.; Joe, M.; Bai, Y.; Kalscheuer, R.; Batista-Gonzalez, A.; Saavedra, N.; Chen, T.; Blanc, C.; (Hung, S.-C.); Tripathi, A.; Xu, J.; Glatman-Freedman, A.; Jacobs, W.; Chan, J.; Porcelli, S.; Achkar, J.; Casadevall, A., Enhanced Control of Mycobacterium tuberculosis Extrapulmonary Dissemination in Mice by an Arabinomannan-Protein Conjugate Vaccine, PLOS PATHOGENS, vol. 13, e1006250, 2017
2017 Trees-Juen Chuang*, Yu-Hsiang Tseng, Chia-Ying Chen, Yi-Da Wang, Assessment of imprinting- and genetic variation-dependent monoallelic expression using reciprocal allele descendants between human family trios, SCIENTIFIC REPORTS, vol. 7(1), 7038, 2017
2017 Cheng WC, Wang JH, Yun WY, Li HY, Hu JM, Rapid preparation of (3R,4S,5R) polyhydroxylated pyrrolidine-based libraries to discover a pharmacological chaperone for treatment of Fabry disease., European journal of medicinal chemistry, vol. 126, 1-6, 2017
2017 Chen KT, Lin CK, Guo CW, Chang YF, Hu CM, Lin HH, Lai Y, Cheng TR, Cheng WC, Effect of the lipid II sugar moiety on bacterial transglycosylase: the 4-hydroxy epimer of lipid II is a TGase inhibitor., CHEMICAL COMMUNICATIONS, vol. 53(4), 771-774, 2017
2017 Lin TW, Chang CF, Chang YJ, Liao YH, Yu HM, (Chen YR)*., Alzheimer's amyloid-β A2T variant and its N-terminal peptides inhibit amyloid-β fibrillization and rescue the induced cytotoxicity, PLOS ONE, vol. 12(3), e0174561, 2017
2017 Jen-Hsuan Chang, Ping-Hsing Tsai, Wei Chen, Shih-Hwa Chiou*, Chung-Yuan Mou*, Dual Delivery of siRNA and Plasmid DNA Using Mesoporous Silica Nanoparticles to Differentiate Induced Pluripotent Stem Cells into Dopaminergic Neurons, Journal of Materials Chemistry B, vol. 5, 3012-3023, 2017
2017 Cheng-Chung Chou*, Wei Chen, Yann Hung, Chung-Yuan Mou, Molecular Elucidation of Biological Response to Mesoporous Silica Nanoparticles in Vitro and in Vivo, ACS Appl. Mater. Interfaces, vol. 9, 22235-22251, 2017
2017 NCD Risk Factor Collaboration (NCD-RisC, Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults., Lancet (London, England), vol. 390(10113), 2627-2642, 2017
2017 NCD Risk Factor Collaboration (NCD-RisC, Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants., Lancet (London, England), vol. 389(10064), 37-55, 2017
2017 Chan HLY, (Chen CJ, Omede O, Al Qamish J, Al Naamani K, Bane A, Tan SS, Simonova M, Cardenas I, Derbala M, Akin O, Phillips RO, Abdelmageed MK, Abdulla M, Adda D, Al Baqali A, Al Dweik N, Al Ejji K, Al Ghazzawi I, Al Kaabi S, Al Sadadi M, Al Salman J, AlBadri M, Al-Busafi SA, Al-Romaihi HE, Ampofo W, Antonov K, Anyaike C, Arome F, Blach S, Borodo MM, Brandon SM, Bright B, Butt MT, Chen DS, Chen PJ, Chien RN, Chuang WL, Cuellar D, Elbardiny AA, Estes C, Farag E, Fung J, Gamkrelidze I, Garcia V, Genov J, Ghandour Z, Ghuloom M, Gomez B, Gunter J, Habeeb J, Hajelssedig O, Hamoudi W, Himatt SM, Hrstic I, Hu CC, Huang CF, Hui YT, Jahis R, Jelev D, John AK, Kaliaskarova KS, Kamel Y, Kao JH, Khamis J, Khattabi H, Khoudri I, Konysbekova A, Kotzev I, Lai MS, Lao WC, Layden J, Lee MH, Lesi O, Li M, Lo A, Loo CK, Luksic B, Maaroufi A, Malu AO, Mateva L, Mitova R, Mohamed R, Morovic M, Murphy K, Mustapha B, Nersesov A, Ngige E, Njouom R, Njoya O, Nonkovic D, Obekpa S, Oguche S, Okolo EE, Omuemu C, Ondoa P, Opare-Sem O, Owusu-Ofori S, Prokopenko YN, Razavi H, Razavi-Shearer D, Razavi-Shearer K, Redae B, Reic T, Rinke de Wit T, Rios C, Robbins S, Roberts LR, Sanad SJ, Schmelzer JD, Sharma M, Su TH, Sultan K, Tchernev K, Tsang OTY, Tsang S, Tzeuton C, Ugoeze S, Uzochukwu B, Vi R, Vince A, Wani HU, Wong VWS, Workneh A, Yacoub R, Yesmembetov KI, Youbi M, Yuen MF, Nde H, The present and future disease burden of hepatitis C virus infections with today's treatment paradigm: Volume 4., Journal of viral hepatitis, vol. 24 Suppl 2, 25-43, 2017
2017 Zeng H, Wu HC, Wang Q, Yang HI, (Chen CJ, Santella RM, Shen J, Telomere Length and Risk of Hepatocellular Carcinoma: A Nested Case-control Study in Taiwan Cancer Screening Program Cohort., Anticancer research, vol. 37(2), 637-644, 2017
2017 Nai YS, Chen TH, Huang YF, Midha MK, Shiau HC, Shen CY, (Chen CJ, Yu AL, Chiu KP, T Oligo-Primed Polymerase Chain Reaction (TOP-PCR): A Robust Method for the Amplification of Minute DNA Fragments in Body Fluids., Scientific reports, vol. 7, 40767, 2017
2017 Chen DS, Hamoudi W, Mustapha B, Layden J, Nersesov A, Reic T, Garcia V, Rios C, Mateva L, Njoya O, Al-Busafi SA, Abdelmageed MK, Abdulla M, Adda D, Akin O, Al Baqali A, Al Dweik N, Al Ejji K, Al Ghazzawi I, Al Kaabi S, Al Naamani K, Al Qamish J, Al Sadadi M, Al Salman J, AlBadri M, Al-Romaihi HE, Ampofo W, Antonov K, Anyaike C, Arome F, Bane A, Blach S, Borodo MM, Brandon SM, Bright B, Butt MT, Cardenas I, Chan HLY, (Chen CJ, Chen PJ, Chien RN, Chuang WL, Cuellar D, Derbala M, Elbardiny AA, Estes C, Farag E, Fung J, Gamkrelidze I, Genov J, Ghandour Z, Ghuloom M, Gomez B, Gunter J, Habeeb J, Hajelssedig O, Himatt SM, Hrstic I, Hu CC, Huang CF, Hui YT, Jahis R, Jelev D, John AK, Kaliaskarova KS, Kamel Y, Kao JH, Khamis J, Khattabi H, Khoudri I, Konysbekova A, Kotzev I, Lai MS, Lao WC, Lee MH, Lesi O, Li M, Lo A, Loo CK, Luksic B, Maaroufi A, Malu AO, Mitova R, Mohamed R, Morovic M, Murphy K, Nde H, Ngige E, Njouom R, Nonkovic D, Obekpa S, Oguche S, Okolo EE, Omede O, Omuemu C, Ondoa P, Opare-Sem O, Owusu-Ofori S, Phillips RO, Prokopenko YN, Razavi H, Razavi-Shearer D, Razavi-Shearer K, Redae B, Rinke de Wit T, Robbins S, Roberts LR, Sanad SJ, Sharma M, Simonova M, Su TH, Sultan K, Tan SS, Tchernev K, Tsang OTY, Tsang S, Tzeuton C, Ugoeze S, Uzochukwu B, Vi R, Vince A, Wani HU, Wong VWS, Workneh A, Yacoub R, Yesmembetov KI, Youbi M, Yuen MF, Schmelzer JD, Strategies to manage hepatitis C virus infection disease burden-Volume 4., Journal of viral hepatitis, vol. 24 Suppl 2, 44-63, 2017
2017 Liu J, Hu HH, Lee MH, Korenaga M, Jen CL, Batrla-Utermann R, Lu SN, Wang LY, Mizokami M, (Chen CJ, Yang HI, Serum Levels of M2BPGi as Short-Term Predictors of Hepatocellular Carcinoma in Untreated Chronic Hepatitis B Patients., Scientific reports, vol. 7(1), 14352, 2017
2017 Huang CF, Yeh ML, Huang CI, Lin YJ, Tsai PC, Lin ZY, Chan SY, Chen SC, Yang HI, Huang JF, Lu SN, Dai CY, Jen CL, Yuan Y, L'Italien G, Wang LY, Lee MH, Yu ML, Chuang WL, (Chen CJ, Risk of hepatitis C virus related hepatocellular carcinoma between subjects with spontaneous and treatment-induced viral clearance., Oncotarget, vol. 8(27), 43925-43933, 2017
2017 Wu MM, Li CF, Lin LF, Wang AS, Pu YS, Wang HH, Mar AC, (Chen CJ, Lee TC, Promoter hypermethylation of LGALS4 correlates with poor prognosis in patients with urothelial carcinoma., Oncotarget, vol. 8(14), 23787-23802, 2017
2017 Wu HC, Yang HI, Wang Q, (Chen CJ, Santella RM, Plasma DNA methylation marker and hepatocellular carcinoma risk prediction model for the general population., Carcinogenesis, vol. 38(10), 1021-1028, 2017
2017 Fan YC, Chou CC, You SL, Sun CA, (Chen CJ, Bai CH, Impact of Worsened Metabolic Syndrome on the Risk of Dementia: A Nationwide Cohort Study., Journal of the American Heart Association, vol. 6(9), e004749, 2017
2017 Kawakita D, Lee YA, Li Q, Chen Y, (Chen CJ, Hsu WL, Lou PJ, Zhu C, Pan J, Shen H, Ma H, Cai L, He B, Wang Y, Zhou X, Ji Q, Zhou B, Wu W, Ma J, Boffetta P, Zhang ZF, Dai M, Hashibe M, Impact of oral hygiene on head and neck cancer risk in a Chinese population., Head & neck, vol. 39(12), 2549-2557, 2017
2017 Maaroufi A, Vince A, Himatt SM, Mohamed R, Fung J, Opare-Sem O, Workneh A, Njouom R, Al Ghazzawi I, Abdulla M, Kaliaskarova KS, Owusu-Ofori S, Abdelmageed MK, Adda D, Akin O, Al Baqali A, Al Dweik N, Al Ejji K, Al Kaabi S, Al Naamani K, Al Qamish J, Al Sadadi M, Al Salman J, AlBadri M, Al-Busafi SA, Al-Romaihi HE, Ampofo W, Antonov K, Anyaike C, Arome F, Bane A, Blach S, Borodo MM, Brandon SM, Bright B, Butt MT, Cardenas I, Chan HLY, (Chen CJ, Chen DS, Chen PJ, Chien RN, Chuang WL, Cuellar D, Derbala M, Elbardiny AA, Estes C, Farag E, Gamkrelidze I, Garcia V, Genov J, Ghandour Z, Ghuloom M, Gomez B, Gunter J, Habeeb J, Hajelssedig O, Hamoudi W, Hrstic I, Hu CC, Huang CF, Hui YT, Jahis R, Jelev D, John AK, Kamel Y, Kao JH, Khamis J, Khattabi H, Khoudri I, Konysbekova A, Kotzev I, Lai MS, Lao WC, Layden J, Lee MH, Lesi O, Li M, Lo A, Loo CK, Luksic B, Malu AO, Mateva L, Mitova R, Morovic M, Murphy K, Mustapha B, Nde H, Nersesov A, Ngige E, Njoya O, Nonkovic D, Obekpa S, Oguche S, Okolo EE, Omede O, Omuemu C, Ondoa P, Phillips RO, Prokopenko YN, Razavi H, Razavi-Shearer D, Redae B, Reic T, Rinke de Wit T, Rios C, Robbins S, Roberts LR, Sanad SJ, Schmelzer JD, Sharma M, Simonova M, Su TH, Sultan K, Tan SS, Tchernev K, Tsang OTY, Tsang S, Tzeuton C, Ugoeze S, Uzochukwu B, Vi R, Wani HU, Wong VWS, Yacoub R, Yesmembetov KI, Youbi M, Yuen MF, Razavi-Shearer K, Historical epidemiology of hepatitis C virus in select countries-volume 4., Journal of viral hepatitis, vol. 24 Suppl 2, 8-24, 2017
2017 Lai TS, Lee MH, Yang HI, You SL, Lu SN, Wang LY, Yuan Y, L'Italien G, Chien KL, (Chen CJ, High hepatitis C viral load and genotype 2 are strong predictors of chronic kidney disease., Kidney international, vol. 92(3), 703-709, 2017
2017 Lai TS, Lee MH, Yang HI, You SL, Lu SN, Wang LY, Yuan Y, L'Italien G, Chien KL, (Chen CJ, Hepatitis C viral load, genotype, and increased risk of developing end-stage renal disease: REVEAL-HCV study., Hepatology (Baltimore, Md.), vol. 66(3), 784-793, 2017
2017 Polaris Observatory HCV Collaborators, Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study., The lancet. Gastroenterology & hepatology, vol. 2(3), 161-176, 2017
2017 Chang IS, Jiang SS, Yang JC, Su WC, Chien LH, Hsiao CF, Lee JH, Chen CY, Chen CH, Chang GC, Wang Z, Lo FY, Chen KY, Wang WC, Chen YM, Huang MS, Tsai YH, Su YC, Hsieh WS, Shih WC, Shieh SH, Yang TY, Lan Q, Rothman N, (Chen CJ, Chanock SJ, Yang PC, Hsiung CA, Genetic Modifiers of Progression-Free Survival in Never-Smoking Lung Adenocarcinoma Patients Treated with First-Line Tyrosine Kinase Inhibitors., American journal of respiratory and critical care medicine, vol. 195(5), 663-673, 2017
2017 Ramos-Casals M, Zignego AL, Ferri C, Brito-Zeron P, Retamozo S, Casato M, Lamprecht P, Mangia A, Saadoun D, Tzioufas AG, Younossi ZM, Cacoub P, Evidence-based recommendations on the management of extrahepatic manifestations of chronic hepatitis C virus infection., Journal of hepatology, vol. 66(6), 1282-1299, 2017
2017 Hsu KH, Tsui KH, Hsu LI, Chiou HY, (Chen CJ, Dose-Response Relationship between Inorganic Arsenic Exposure and Lung Cancer among Arseniasis Residents with Low Methylation Capacity., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol. 26(5), 756-761, 2017
2017 Butler C, Lee YA, Li S, Li Q, (Chen CJ, Hsu WL, Lou PJ, Zhu C, Pan J, Shen H, Ma H, Cai L, He B, Wang Y, Zhou X, Ji Q, Zhou B, Wu W, Ma J, Boffetta P, Zhang ZF, Dai M, Hashibe M, Diet and the risk of head-and-neck cancer among never-smokers and smokers in a Chinese population., Cancer epidemiology, vol. 46, 20-26, 2017
2017 Lee MH, Huang CF, Lai HC, Lin CY, Dai CY, Liu CJ, Wang JH, Huang JF, Su WP, Yang HC, Kee KM, Yeh ML, Chuang PH, Hsu SJ, Huang CI, Kao JT, Chen CC, Chen SH, Jeng WJ, Yang HI, Yuan Y, Lu SN, Sheen IS, Liu CH, Peng CY, Kao JH, Yu ML, Chuang WL, (Chen CJ, Clinical Efficacy and Post-Treatment Seromarkers Associated with the Risk of Hepatocellular Carcinoma among Chronic Hepatitis C Patients., Scientific reports, vol. 7(1), 3718, 2017
2017 Lin YJ, Shaw TG, Yang HI, Lu SN, Jen CL, Wang LY, Wong KH, Chan SY, Yuan Y, L'Italien G, (Chen CJ, Lee MH, Chronic hepatitis C virus infection and the risk for diabetes: a community-based prospective study., Liver international : official journal of the International Association for the Study of the Liver, vol. 37(2), 179-186, 2017
2017 Seow WJ, Matsuo K, Hsiung CA, Shiraishi K, Song M, Kim HN, Wong MP, Hong YC, Hosgood HD 3rd, Wang Z, Chang IS, Wang JC, Chatterjee N, Tucker M, Wei H, Mitsudomi T, Zheng W, Kim JH, Zhou B, Caporaso NE, Albanes D, Shin MH, Chung LP, An SJ, Wang P, Zheng H, Yatabe Y, Zhang XC, Kim YT, Shu XO, Kim YC, Bassig BA, Chang J, Ho JC, Ji BT, Kubo M, Daigo Y, Ito H, Momozawa Y, Ashikawa K, Kamatani Y, Honda T, Sakamoto H, Kunitoh H, Tsuta K, Watanabe SI, Nokihara H, Miyagi Y, Nakayama H, Matsumoto S, Tsuboi M, Goto K, Yin Z, Shi J, Takahashi A, Goto A, Minamiya Y, Shimizu K, Tanaka K, Wu T, Wei F, Wong JY, Matsuda F, Su J, Kim YH, Oh IJ, Song F, Lee VH, Su WC, Chen YM, Chang GC, Chen KY, Huang MS, Yang PC, Lin HC, Xiang YB, Seow A, Park JY, Kweon SS, (Chen CJ, Li H, Gao YT, Wu C, Qian B, Lu D, Liu J, Jeon HS, Hsiao CF, Sung JS, Tsai YH, Jung YJ, Guo H, Hu Z, Wang WC, Chung CC, Lawrence C, Burdett L, Yeager M, Jacobs KB, Hutchinson A, Berndt SI, He X, Wu W, Wang J, Li Y, Choi JE, Park KH, Sung SW, Liu L, Kang CH, Hu L, Chen CH, Yang TY, Xu J, Guan P, Tan W, Wang CL, Sihoe AD, Chen Y, Choi YY, Hung JY, Kim JS, Yoon HI, Cai Q, Lin CC, Park IK, Xu P, Dong J, Kim C, He Q, Perng RP, Chen CY, Vermeulen R, Wu J, Lim WY, Chen KC, Chan JK, Chu M, Li YJ, Li J, Chen H, Yu CJ, Jin L, Lo YL, Chen YH, Fraumeni JF Jr, Liu J, Yamaji T, Yang Y, Hicks B, Wyatt K, Li SA, Dai J, Ma H, Jin G, Song B, Wang Z, Cheng S, Li X, Ren Y, Cui P, Iwasaki M, Shimazu T, Tsugane S, Zhu J, Jiang G, Fei K, Wu G, Chien LH, Chen HL, Su YC, Tsai FY, Chen YS, Yu J, Stevens VL, Laird-Offringa IA, Marconett CN, Lin D, Chen K, Wu YL, Landi MT, Shen H, Rothman N, Kohno T, Chanock SJ, Lan Q, Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations., Human molecular genetics, vol. 26(2), 454-465, 2017
2017 Hsu LI, Hsieh FI, Wang YH, Lai TS, Wu MM, (Chen CJ, Chiou HY, Hsu KH, Arsenic Exposure From Drinking Water and the Incidence of CKD in Low to Moderate Exposed Areas of Taiwan: A 14-Year Prospective Study., American journal of kidney diseases : the official journal of the National Kidney Foundation, vol. 70(6), 787-797, 2017
2017 Chu YJ, Yang HI, Wu HC, Liu J, Wang LY, Lu SN, Lee MH, Jen CL, You SL, Santella RM, (Chen CJ, Aflatoxin B1 exposure increases the risk of cirrhosis and hepatocellular carcinoma in chronic hepatitis B virus carriers., International journal of cancer, vol. 141(4), 711-720, 2017
2017 Yeh, C.-S., Chang, S.-L., Chen, J.-H., Wang, H.-K., Chou, Y.-C., Wang, C.-H., Huang, S.-H., Larson, A., Pleiss, P. A., Chang, W.-h., Chang, T.-H.)*, The conserved AU-dinucleotide at the 5’ end of nascent U1 snRNA is optimized for the interaction with nuclear cap-binding-complex, NUCLEIC ACIDS RESEARCH, vol. 45 (16), 9679-9693, 2017
2016 Cheung EC, Lee P, Ceteci F, Nixon C, Blyth K, Sansom OJ, Vousden KH, Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine., Genes & development, vol. 30(1), 52-63, 2016
2016 See-Tong Pang, Ying-Hsu Chang, Po-Hung Lin, (Ying-Chih Chang, Yow-sien Lin, Ben Hsieh, Chung-Yi Liu, Cheng-Keng Chuang, Ritu Kamal, Rui Mei*, A Novel biomarker for prostate cancer detection in patient with gray zone PSA level, Urological Science, vol. 27(2), S1-S2, 2016
2016 Si-Hong Lu, Wen-Sy Tsai, Ying-Hsu Chang, Teh-Ying Chou, See-Tong Pang, Po-Hung Lin, Chun-Ming Tsai, Ying-Chih Chang)*, Identifying Cancer Origin Using Circulating Tumor Cells, Cancer Biology & Therapy, vol. 17(4), 430-438, 2016
2016 Jia-Yang Chen, Wen-Sy Tsai, Hung-Jen Shao, Jen-Chia Wu, Jr-Ming Lai, Si-Hong Lu, Tsung-Fu Hung, Chih-Tsung Yang, Liang-Chun Wu, Jinn-Shiun Chen, Wen-Hwa Lee, Ying-Chih Chang, Sensitive and Specific Biomimetic Lipid Coated Microfluidics to Isolate Viable Circulating Tumor Cells and Microemboli for Cancer Detection, PLoS One, vol. 11(3), e0149633, 2016
2016 Ming-Chu Chang, Yu-Ting Chang*, Jia-Yang Chen, Yung-Ming Jeng, Ching-Yao Yang, Yu-Wen Tien, Shih-Hung Yang, Huai-Lu Chen, Ting-Yuan Liang, Chien-Fang Wang, Eva Y.H.P. Lee, (Ying-Chih Chang, Wen-Hwa Lee*, Clinical Significances of Circulating Tumor Microemboli as a Prognostic Marker in Patients with Pancreatic Ductal Adenocarcinoma, CLINICAL CHEMISTRY, vol. 62(3), 505-513, 2016
2016 Wen-Sy Tsai, Jinn-Shiun Chen, Hung-Jen Shao, Jen-Chia Wu, Jr-Ming Lai, Si-Hong Lu, Tsung-Fu Hung, Yen-Chi Chiu, Jeng-Fu You, Pao-Shiu Hsieh, Chien-Yuh Yeh, Hsin-Yuan Hung, Sum-Fu Chiang, Geng-Ping Lin, Reiping Tang, Ying-Chih Chang)*, Circulating Tumor Cell Count Correlates with Colorectal Neoplasm Progression and Is a Prognostic Marker for Distant Metastasis in Non-Metastatic Patients, Scientific Reports, vol. 6, 24517, 2016
2016 Yu Wen Tien, Hsun-Chuan Kuo, Be-Ing Ho, Ming-Chu Chang, Yu-Ting Chang, Mei-Fang Cheng, Huai-Lu Chen, Ting-Yung Liang, Chien-Fang Wang, Chia-Yi Huang, Jin-Yuh Shew, Eva YHP Lee, Wen-Hwa Lee, A High Circulating Tumor Cell Count in Portal Vein Predicts Liver Metastasis From Periampullary or Pancreatic Cancer A High Portal Venous CTC Count Predicts Liver Metastases, MEDICINE, vol. 95(16), e3407, 2016
2016 Ming-Chu Chang, Ying-Chih Chang, Yung-Ming Jeng, Ching-Yao Yang, Yu-Wen Tien, Shih-Hung Yang, Eva Y.H.P. Lee, Wen-Hwa Lee, Yu-Ting Chang, Circulating tumor cluster is a prognostic marker in patients with pancreatic ductal adenocarcinoma, PANCREATOLOGY, vol. 16(4), S53-S53, 2016
2016 • Sachin S Shivatare, Shih-Huang Chang, Tsung-I Tsai, Susan Yu Tseng, Yih-Shyan Lin, Yang-Yu Cheng, Chang-Chun David Lee, Sujeet Pawar, Charng-Sheng Tsai, Hao-Wei Shih, Yi-Fang Zeng, Chi-Hui Liang Peter D. Kwong, Dennis R. Burton, Chung-Yi Wu, * Chi-Huey Wong*, Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies, Nature Chemistry, vol. 8, 338-346, 2016
2016 Li TH, Huang CC, Yang YY, Lee KC, (Hsieh SL, Hsieh YC, Alan L, Lin HC, Lee SD, Tsai CY*, Thalidomide Improves the Intestinal Mucosal Injury and Suppresses Mesenteric Angiogenesis and Vasodilatation by Down-Regulating Inflammasomes-Related Cascades in Cirrhotic Rats, PLoS One, vol. 11(1): e0147212, 1-17, 2016
2016 Tarng DC, Tseng WC, Lee PY, Chiou SH, (Hsieh SL)*., Induced Pluripotent Stem Cell-derived Conditioned Medium Attenuates Acute Kidney Injury by Downregulating the Oxidative Stress-Related Pathway in Ischemia-Reperfusion Rats, CELL TRANSPLANTATION, vol. 25(3), 517-530, 2016
2016 Tung YT, Chang CC, Lin YL, (Hsieh SL, Wang GJ*, Development of double-generation gold nanoparticle chip-based dengue virus detection system combining fluorescence turn-on probes, BIOSENSORS & BIOELECTRONICS, vol. 77, 90-98, 2016
2016 Huang YL, Chen ST, Liu RS, Chen YH, Lin CY, Huang CH, Su PY, Liao CL, (Hsieh SL)*, CLEC5A is Critical for Dengue Virus-induced Osteoclast Activation and Bone Homeostasis, JOURNAL OF MOLECULAR MEDICINE-JMM, vol. 94(9), 1025-1037, 2016
2016 Fan WC, Liu CW, Ou SM, Huang CC, Li TH, Lee KC, Huang SF, Yang YY, Hsieh YC, (Hsieh SL, Hou MC, Lin HC*, TLR4/CD14 Variants-Related Serologic and Immunologic Dys-Regulations Predict Severe Sepsis in Febrile De-Compensated Cirrhotic Patients, PLoS One, vol. 11(11): e0166458, 1-19, 2016
2016 Li TH, Lee PC, Lee KC, Hsieh YC, Tsai CY, Yang YY, Huang SF, Tsai TH, (Hsieh SL, Hou MC, Lin HC, Lee SD*, Down-regulation of common NFκB-iNOS pathway by chronic Thalidomide treatment improves Hepatopulmonary Syndrome and Muscle Wasting in rats with Biliary Cirrhosis, SCIENTIFIC REPORTS, vol. 6: 39405, 1-14, 2016
2016 Cheung SK, Chuang PK, Huang HW, Hwang-Verslues WW, Cho CH, Yang WB, Shen CN, (Hsiao M, Hsu TL, Chang CF, Wong CH, Stage-specific embryonic antigen-3 (SSEA-3) and beta3GalT5 are cancer specific and significant markers for breast cancer stem cells., Proceedings of the National Academy of Sciences of the United States of America, vol. Jan 26;113(4):960-965. Cite 1, 2016
2016 Sung PL, Jan YH, Lin SC, Huang CC, Lin H, Wen KC, Chao KC, Lai CR, Wang PH, Chuang CM, Wu HH, Twu NF, Yen MS, (Hsiao M)*, Huang CF, Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma., Oncotarget, vol. Jan 26;7(4):4036-4047, 2016
2016 Chen CW, Huang JH, Lai TC, Jan YH, (Hsiao M)*, Chen CH, Hwu YK, Liu RS, Evaluation of the intracellular uptake and cytotoxicity effect of TiO2 nanostructures for various human oral and lung cells under dark conditions, Toxicology Research, vol. 5:303-311, 2016
2016 Adebayo BO, Huang WC, Lee WH, Wu AT, Wang LS, (Hsiao M, Yeh CT, Chao TY, Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448, BMC Cancer, vol. Feb 25;16(1):160, 2016
2016 Lin TC, Su CY, Lai TC, Pan WA, Jan YH, Yeh CT, Chen CL, Ger LP, Chang HT, Yang CJ, Huang MS, Shyy JY, Tsai MD, (Hsiao M)*, NIFK promotes cancer metastasis through Runx1-dependent repression of casein kinase 1α to activate Wnt/b-catenin signaling, eLife, vol. Mar 17;5:e11288, Cite 15, 2016
2016 Liu YP, Lee JJ, Lai TC, Lee CH, Hsiao YW, Chen PS, Liu WT, Hong CY, Lin SK, Ping Kuo MY, Lu PJ, (Hsiao M)*, Suppressive function of low-dose deguelin on the invasion of oral cancer cells by downregulating tumor necrosis factor alpha-induced nuclear factor-kappa B signaling., Head and Neck-Journal for the Sciences and Specialties of the Head and Neck, vol. Apr;38 Suppl 1, E524-E534, 2016
2016 Li YJ, Huang TH, (Hsiao M, Lin BR, Cheng SJ, Yang CN, Lai WT, Wu TS, Fan JR, Kuo MY, Chang CC, Suppression of fructose-bisphosphate aldolase C expression as a predictor of advanced oral squamous cell carcinoma., Head and Neck-Journal for the Sciences and Specialties of the Head and Neck, vol. Apr;38 Suppl 1, E1075-E1085, 2016
2016 Lin YW, Lee LM, Lee WJ, Chu CY, Tan P, Yang YC, Chen WY, Yang SF, (Hsiao M, Chien MH, Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB-DNAbinding activity, Journal of Pineal Research, vol. Apr;60(3):277-290, 2016
2016 Hsu CY, Lin CH, Jan YH, Su CY, Yao YC, Cheng HC, Hsu TI, Wang PS, Su WP, Yang CJ, Huang MS, Calkins MJ, (Hsiao M)*, Lu PJ, Huntingtin-Interacting Protein-1 Is an Early-stage Prognostic Biomarker of Lung Adenocarcinoma and Suppresses Metastasis via Akt-mediated EMT., American Journal of Respiratory and Critical Care Medicine, vol. Apr 15;193(8):869-880, Cite 10, 2016
2016 Cheng PW, Lee HC, Lu PJ, Chen HH, lai CC, Sun GC, Yen TC, (Hsiao M, Lin YT, Liu CP, Tseng CJ, Resveratrol inhibition of Rac1-derived reactive oxygen species by AMPK decreases blood pressure in a fructose-induced rat model of hypertension, Scientific Reports, vol. May 3;6:25342, 2016
2016 Yeh SC, Wang PY, Lou YW, Khoo KH, (Hsiao M, Hsu TL, Wong CH, Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity., Proceedings of the National Academy of Sciences of the United States of America, vol. May 17;113(20), 5592-5597, 2016
2016 Su YH, Huang WC, Huang TH, Huang YJ, Sue YK, Huynh TT, (Hsiao M, Liu TZ, AT Wu, Lin CM, Folate deficient tumor microenvironment promotes epithelial-to-mesenchymal transition and cancer stem-like phenotypes., Oncotarget, vol. May 31;7(22):33246-33256, 2016
2016 Chang YC, Su CY, (Hsiao M)*, Therapeutic targeting of methylthioadenosine phosphorylase , Cancer Cell & Microenvironment, vol. June;3:e1322. (Invited Review), 2016
2016 Kosheleva OK, Lai TC, Chen NG, (Hsiao M)*, Chen CH*, Selective killing of cancer cells by nanoparticle-assisted ultrasound., Journal of Nanobiotechnology, vol. June 14;14(1):46, 2016
2016 Chan YC, Chen CW, Chan MH, Chang YC, Chang MW, Chi LH, Yu HM, Lin YF, Tsai DP, Liu RS, (Hsiao M)*, MMP2-sensing up-conversion nanoparticle for fluorescence biosensing in head and neck cancer cells, Biosensors & Bioelectronics, vol. Jun 15;80:131-139, Cite 17, 2016
2016 Lin CH, Tsai CH, Yeh CT, Liang JL, Hung WC, Lin FC, Chang WL, Li HY, Yao YC, Hsu TI, Lee YC, Wang YC, Sheu BS, Lai WW, Calkins MJ, (Hsiao M)*, Lu PJ, MiR-193a-5p/ERBB2 act as concurrent chemoradiation therapy response indicator of esophageal squamous cell carcinoma., Oncotarget, vol. June 28;7(26):39680-39693, 2016
2016 Peng HY, Jiang SS, Hsiao JR, (Hsiao M, Hsu YM, Wu GH, Chang WM, Chang JY, Jin SC, Shiah SG, IL-8 induces miR-424-5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinoma, Mol Oncol, vol. Jun;10(6), 895-909, 2016
2016 Yang YC, Cheng TY, Huang SM, Su CY, Yang PW, Lee JM, Chen CK, (Hsiao M, Hua KT, Kuo ML, Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR association., Oncogene, vol. Jun 30;35(26), 3387-98, 2016
2016 Lin CW, Yang WE, Lee WJ, Hua KT, Hsieh FK, (Hsiao M, Chen CC, Chow JM, Chen MK, Yang SF, Chien MH, Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with favourable prognosis., Carcinogenesis, vol. Jul;37(7), 712-722, 2016
2016 Su CY, Chang YC, Yang CJ, Huang MS, (Hsiao M)*, The opposite prognostic effect of NDUFS1 and NDUFS8 forms a prognostic panel for non-small cell lung cancer by reflecting the oncojanus role of mitochondrial complex I, Scientific Reports, vol. Aug 12;6, 31357, 2016
2016 Chen CK, Yu WH, Cheng TY, Chen MW, Su CY, Yang YC, Kuo TC, Lin MT, (Hsiao M, Hua KT, Hung MC, Kuo ML, Inhibition of VEGF165/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis, Scientific Reports, vol. Aug 10;6, 31398, 2016
2016 Lai CC, Cheng PW, Yeh TC, Lu PJ, (Hsiao M, Liu CP, Tseng CJ, Paricalcitol attenuates cardiac fibrosis and expression of endothelial cell transition markers in isoproterenol-induced cardiomyopathic rats, Critical Care Medicine, vol. 44(9), e866-e874, 2016
2016 Wei L, Su YK, Lin CM, Chao TY, Huynh TT, Jan HJ, Whang-Peng J, Chiou JF, Wu AT, (Hsiao M)*, Preclinical investigation of Ibrutinib, a Bruton’s kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes, Oncotarget, vol. Oct. 25;7(43), 69961-975, 2016
2016 Chan MH, Chen CW, Lee IJ, Chan YC, Tu DT, (Hsiao M)*, Chen CH, Chen XY, Liu RS, Near-infrared light-mediated photodynamic therapy nanoplatform by electrostatic assembly of NaYF4:Yb/Tm upconversion nanoparticles with graphitic carbon nitride quantum dots, Inorganic Chemistry, vol. 55(20), 10267-10277, 2016
2016 Chen CW, Chan YC, (Hsiao M)*, Liu RS, Plasmon-enhanced photodynamic cancer therapy by upconversion nanoparticles conjugated with Au nanorods, ACS Applied Materials & Interfaces, vol. 1, 1, 2016
2016 Lo YL, Liou GG, Lyu JH, (Hsiao M, Hsu TL, Wong CH*, Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex., PLoS One, vol. Nov 10;11(11), e0166474, 2016
2016 Chen HH, Cheng PW, Ho WY, Lu PJ, Lai CC, Tseng YM, Fang HC, Sun GC, (Hsiao M, Liu CP, Tseng CJ, Renal denervation improves the baroreflex and GABA system normalization in chronic kidney disease-associated hypertension, Scientific Reports, vol. 6, 38447, 2016
2016 Kuo TC, Chen CK, Hua KT, Yu P, Lee WJ, Chen MW, Jeng YM, Chien MH, Kuo KT, (Hsiao M, Kuo ML, Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells., Cancer Letters, vol. Dec 28;383(2), 282-294, 2016
2016 Chang WM, Lin YF, Su CY, Peng HY, Chang YC, Lai TC, Wu GH, Hsu YM, Chi LH, Hsiao JR, Chen CL, Chang JY, Shieh YS, (Hsiao M)*, Shiah SG, Dysregulation of Runx2/Activin A axis upon miR376c downregulation promotes lymph node metastasis in head and neck squamous cell carcinoma., Cancer Research, vol. 76(24),7140-7150, Cite 16, 2016
2016 L. Krasnova, C.-H. Wong, Understanding the Chemistry and Biology of Glycosylation with Glycan Synthesis, Annual Review of Biochemistry, vol. 85, 599-630, 2016
2016 G. B. E. Stewart-Jones, C. Soto, T. Lemmin, G.-Y. Chuang, A. Druz, R. Kong, P. V. Thomas, K. Wagh, T. Zhou, A.-J. Behrens, T. Bylund, C. W. Choi, J. R. Davison, I. S. Georgiev, M. G. Joyce, Y. D. Kwon, M. Pancera, J. Taft, Y. Yang, B. Zhang, S. S. Shivatare, V. S. Shivatare, C.-C. D. Lee, C.-Y. Wu, C. A. Bewley, D. R. Burton, W. C. Koff, M. Connors, M. Crispin, B. T. Korber, C.-H. Wong, J. R. Mascola, P. D. Kwong, Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G., Cell, vol. 165(4), 813-826, 2016
2016 C.-H. Hsu, S. Park, D. E. Mortenson, B. L. Foley, X. Wang, R. J. Woods, D. A. Case, E. T. Powers, C.-H. Wong, H. J. Dyson, J. W. Kelly, The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate., Journal of the American Chemical Society, vol. 138(24), 7636-7648, 2016
2016 S. K. C. Cheung, P.-K. Chuang, H.-W. Huang, W. W. Hwang-Verslues, C. H.-H. Cho, W.-B. Yang, C.-N. Shen, M. Hsiao, T.-L. Hsu, C.-F. Chang, C.-H. Wong, Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells., Proceedings of the National Academy of Sciences of the United States of America, vol. 113(4), 960-965, 2016
2016 T.-C. Kuo, L.-W. Li, S.-H. Pan, J.-M. Fang, J.-H. Liu, T.-R. Cheng, C.-J. Wang, P.-F. Hung, H.-Y. Chen, T.-M. Hong, Y.-L .Hsu, C.-H. Wong, P.-C. Yan, Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin., JOURNAL OF MEDICINAL CHEMISTRY, vol. 59(18), 8521-8534, 2016
2016 T.-N. Wu, K.-H. Lin, Y.-T. Wu, J.-R. Huang, J.-T. Hung, J.-C. Wu, C.-Y. Chen, K.-C. Chu, N.-H. Lin, A. L.Yu, C.-H. Wong, Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation., ACS chemical biology, vol. 11(12), 3431-3441, 2016
2016 P.-C. Wang, J.-M. Fang, K.-C. Tsai, S.-Y. Wang, W.-I. Huang, Y.-S. Cheng, R. C., C.-H. Wong, Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors., Journal of medicinal chemistry, vol. 59(11), 5297-5310, 2016