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B. R. Chen, W. M. Li, T. L. Li, Y. L. Chan, C. J. Wu*, Fucoidan from Sargassum hemiphyllum inhibits infection and inflammation of Helicobacter pylori, SCIENTIFIC REPORTS, vol. 12(1), 429, 2022 |
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Y. C. Pan, Y. L. Wang, S. I. Toh, N. S. Hsu, K. H. Lin, Z. Xu, S. C. Huang, T. K. Wu, T. L. Li, C. Y. Chang*, Dual-mechanism confers self-resistance to the antituberculosis antibiotic capreomycin, ACS CHEMICAL BIOLOGY, vol. 17(1), 138-146, 2022 |
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C. C. Liaw, I. W. Lo, Y. C. Lin, H. T. Huang, L. J. Zhang, P. C. Hsiao, T. L. Li, * Y. H. Kuo*, Four cucurbitane glycosides taimordisins A–D with novel furopyranone skeletons isolated from the fruits of Momordica charantia, FOOD CHEMISTRY: X, vol. 14, 100286, 2022 |
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S. M. Zadeh, M. H. Chen, Z. C. Wang, E. K. Astani, I. W. Lo, K. H. Lin, N. S. Hsu, K. Adhikari, S. Y. Lyu, H. Y. Tsai, Y. Terasawa, M. Yabe, K. Yamamoto, S. Ichikawa, T. L. Li*, β-Hydroxylation of α-amino-β-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin, COMMUNICATIONS CHEMISTRY, vol. 5, 87, 1-16, 2022 |
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E. Astani, S. M. Zadeh, N. S. Hsu, K. H. Lin, S. Sardari, T. L. Li*, Intermolecular Interactions of Nucleoside Antibiotic Tunicamycin with On-Target MraYcb-TUN and Off-Target DPAGT1-TUN in the Active Sites Delineated by Quantum Mechanics/Molecular Mechanics Calculations, ACS OMEGA, vol. 7(37), 32970-32987, 2022 |
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Z. C. Wang, I. W. Lo, K. H. Lin, A. N. Cheng, S. M. Zadeh, Y. H. Huang, T. L. Li*, Genetic and biochemical characterization of halogenation and drug-transportation genes encoded in the albofungin biosynthetic gene cluster, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 88(17):e0080622, 1-20, 2022 |
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I. W. Lo, G. Y. Liao, J. C. Lee, C. I. Chang, Y. C. Wu, S. P. Liu, H. J. Su, C. I. Liu, C. Y. Kuo, Z.Y. Lin, T. L. Li*, Y. S. Lin*, C. C. Liaw*, Novel Aporphine- and Proaporphine-Clerodane Hybrids Identified from the Barks of Taiwanese Polyalthia Longifolia var. pendula with Strong Anti-DENV2 Activity, PHARMACEUTICS, vol. 15(10), 1218, 1-15, 2022 |
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H. T. Huang, I. W. Lo, G. Y. Liao, Y. C. Lin, Y. C. Shen, H. C. Huang, T. L. Li, K. T. Lee, Y. H. Kuo*, C. C. Liaw*, Anti-inflammatory sesquiterpene and triterpene acids from Mesona procumbens Hemsley, FRONTIERS IN CHEMISTRY, vol. 10:1003356, 1-13, 2022 |
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Hsu YS, Wu PJ, Jeng YM, Hu CM*, Lee WH*., Differential Effects of Glucose and N-acetylglucosamine on Genome instability., Am J Cancer Res, vol. 12, 1556-1567, 2022 |
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Chen YI, Chang CC, Hsu MF, Jeng YM, Tien YW, Chang MC, Chang YT, Hu CM*, Lee WH*, Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation., Nature communications, vol. 13, 2945, 2022 |
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Liu Yu-Huei, Hu Chun-Mei, Hsu Yuan-Sheng, Lee Wen-Hwa, Interplays of glucose metabolism and KRAS mutation in pancreatic ductal adenocarcinoma, Cell Death & Disease, vol. 13(9), 817-826, 2022 |
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Lee Wen-Hsin, Chen Xiaorui, Liu I-Ju, Lee Jiin-Horng, Hu Chun-Mei, Wu Han-Chung, Wang Sheng-Kai, Lee Wen-Hwa, Ma Che, Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation, Cell Reports, vol. 41(4), 111555, 2022 |
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Chen Jia-Yang, Chou Hsu-Huan, Lim Syer Choon, Huang Yen-Jang, Lai Kuan-Chen, Guo Chin-Lin, Tung Chien-Yi, Su Chung-Tsai, Wang Jocelyn, Liu Edward, Han Hsiao-Fen, Yeh Po-Ying, Hu Chun-Mei, Dunn Alexander R., Frank Curtis W., Wu Yi-Chun, Yang Muh-Hwa, Chang Ying-Chih, Multiomic characterization and drug testing establish circulating tumor cells as an ex vivo tool for personalized medicine, iScience, vol. 25(10), 105081, 2022 |
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Weng WC, Liao HE, Huang SP, Tsai ST, Hsu HC, Liew CY, Gannedi V, Hung SC, Ni CK, Unusual free oligosaccharides in human bovine and caprine milk., Scientific Reports, vol. 12(1), 10790, 2022 |
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Liew CY, Hsu HC, Nguan HS, Huang YC, Zhong YQ, Hung SC, Ni CK, The Good, the Bad, and the Ugly Memories of Carbohydrate Fragments in Collision-Induced Dissociation., Journal of the American Society for Mass Spectrometry, vol. 33(10), 1891-1903, 2022 |
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Wang Chih-Hung, Chang Jia-Ru, Hung Shang-Cheng, Dou Horng-Yunn, Lee Gwo-Bin, Rapid molecular diagnosis of live Mycobacterium tuberculosis on an integrated microfluidic system, Sensors and Actuators B: Chemical, vol. 12(1), 10790, 2022 |
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Tseng KY, Tzeng ZH, Cheng TR, Liang PH, Hung SC, Design and Synthesis of 1-O- and 6 |
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Byung-sun Jeon, Teng-Yi Huang, Mark W. Ruszczycky, Sei-hyun Choi, Namho Kim, Joseph Livy Franklin, (Shang-Cheng Hung*, Hung-wen Liu*, Byproduct formation during the biosynthesis of spinosyn A and evidence for an enzymatic interplay to prevent its formation, TETRAHEDRON, vol. 103, 132569, 2022 |
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Teng KC, Tseng KY, Tzeng ZH, Hung SC, A concise synthesis of L-gulose and its C-6 derivatives., Bioorganic & Medicinal Chemistry, vol. 73, 117029, 2022 |
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Lu Tsung-Han, Chiang Nai-Jung, Tsai Yi-Cheng, Gopinathan Priya, Huang Chien-Jui, Chang Jui-Lin, Tu Hsiu-Chi, Shan Yan-Shen, Hung Shang-Cheng, Lee Gwo-Bin, An integrated microfluidic system for cholangiocarcinoma diagnosis from bile by using specific affinity probes, Sensors and Actuators B: Chemical, vol. 373, 132724, 2022 |
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Uchimura K, Nishitsuji K, Chiu LT, Ohgita T, Saito H, Allain F, Gannedi V, Wong CH, Hung SC, Design and Synthesis of 6-O-Phosphorylated Heparan Sulfate Oligosaccharides to Inhibit Amyloid beta Aggregation., Chembiochem : a European journal of chemical biology, vol. 23(15), e202200191, 2022 |
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Tai‑Wei Chiang, Te‑Lun Mai, Trees‑Juen Chuang*, CircMiMi: a stand‑alone software for constructing circular RNA‑microRNA‑mRNA interactions across species, BMC Bioinformatics, vol. 23, 164, 2022 |
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Te-Lun Mai, Chia-Ying Chen, Yu-Chen Chen, Tai-Wei Chiang, Trees-Juen Chuang*, Trans-genetic effects of circular RNA expression quantitative trait loci and potential causal mechanisms in autism, MOLECULAR PSYCHIATRY, vol. 27, 4695-4706 (SCI impact factor: 9.6; Rank (PSYCHIATRY): 6/276), 2022 |
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Lee Hua-Yun, Chiang Po-Yu, Wu Hsi-Ju, Wang Ting-Yi, Yang Tzu-Ching, Cheng Wei-Chieh, Lo Lee-Chiang, Liao Wei-Ssu, Versatile Azido-Functionalized Carbon Dots for Cancer Cell Imaging, ACS Applied Nano Materials, vol. 5(9), 12374-12379, 2022 |
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Chen WA, Li HY, Sayyad A, Huang CY, Cheng WC, Synthesis of Nitrone-derived Pyrrolidine Scaffolds and Their Combinatorial Libraries to Develop Selective alpha-l-Rhamnosidase Inhibitors., Chemistry, an Asian journal, vol. 17(14), e202200172, 2022 |
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Guo CW, Chen KT, You TY, Lin CC, Cheng WC, Synthesis and Evaluation of Diverse N-Substituted Disaccharide Dipeptides for Human NOD2 Stimulation Activity., Chemistry, an Asian journal, vol. 17(4), e202101169, 2022 |
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Chen Wei-An, Chen Yu-Hsin, Hsieh Chiao-Yun, Hung Pi-Fang, Chen Chiao-Wen, Chen Chien-Hung, Lin Jung-Lee, Cheng Ting-Jen R., Hsu Tsui-Ling, Wu Ying-Ta, Shen Chia-Ning, Cheng Wei-Chieh, Harnessing natural-product-inspired combinatorial chemistry and computation-guided synthesis to develop N-glycan modulators as anticancer agents, Chemical Science, vol. 13, 6233-6243, 2022 |
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Tseng YY, Liou JM, Cheng WC, Hsu JT, Hsu TL, Wu MS, Wong CH, Combating multidrug-resistant Helicobacter pylori with moenomycin A in combination with clarithromycin or metronidazole., Frontiers in chemistry, vol. 10, 897578, 2022 |
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Wan-Chin Chiang§, Yu-Sheng Fang§, Yuh-Shen Lye, Tzu-Yu Wong, Kiruthika Ganesan, Shih-Chieh Chou, (Yun-Ru Chen)*, Hyperphosphorylation-mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric Stage, ACS Chemical Neuroscience, vol. 37, 1, 2599-2612, 2022 |
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Ming-Che Lee‡, Yi-Hung Liao‡, Shih-Hui Chen, Yun-Ru Chen)*., Amyloid-β E22K Fibril in Familial Alzheimer’s Disease is More Thermo-stable and Susceptible to Seeding., IUBMB LIFE, vol. 74(8), 739-747, 2022 |
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Bijan Ferdows, Dylan Patel, Wei Chen*, Xiangang Huang, Na Kong, Wei Tao*, RNA cancer nanomedicine: nanotechnology-mediated RNA therapy, Nanoscale, vol. 14, 4448-4455, 2022 |
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Dongxiao Zhang, Danni Zhong, Jiang Ouyang, Jian He, Yuchen Qi, Wei Chen, Xingcai Zhang*, Wei Tao*, Min Zhou*, Microalgae-based oral microcarriers for gut microbiota homeostasis and intestinal protection in cancer radiotherapy, Nature Communications, vol. 13, 1413, 2022 |
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Yufen Xiao, Zhongmin Tang, Xiangang Huang, Wei Chen, Jun Zhou, Haijun Liu, Chuang Liu, Na Kong*, Wei Tao*, Emerging mRNA technologies: delivery strategies and biomedical applications, Chemical Society Reviews, vol. 51, 3828-3845, 2022 |
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Jiang Ouyang, Siyuan Rao, Runcong Liu, Liqiang Wang, Wei Chen, Wei Tao*, Na Kong*, 2D materials-based nanomedicine: From discovery to applications, Advanced Drug Delivery Reviews, vol. 185, 114268, 2022 |
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Jiang Ouyang, Wei Chen*, Wei Tao*, Design of application-optimized hydrogels based on a swollen polymer network model, Matter, vol. 5, 2471-2473, 2022 |
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Xiaoyuan Ji*, Zhongmin Tang, Haijun Liu, Yong Kang, Liqun Chen, Jinrui Dong, Wei Chen, Na Kong, Wei Tao*, Tian Xie*, Nanoheterojunction-Mediated Thermoelectric Strategy for Cancer Surgical Adjuvant Treatment and β-Elemene Combination Therapy., Advanced Materials, vol. 35, 2207391, 2022 |
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Yaxin Chen, Duotian Qin, Jianhua Zou, Xiaobin Li, Xin Dong Guo, Yi Tang, Chuang Liu, Wei Chen, Na Kong, Can Yang Zhang*, Wei Tao*, Living Leukocyte-Based Drug Delivery Systems, Advanced Materials, vol. 35, 2207787, 2022 |
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Wu MM*, Chen CW, Chen CY, Lee CH, Chou M, Hsu LI, Lee TC, (Chen CJ, TIMP3 Gene Polymorphisms of -1296 T > C and -915 A > G Increase the Susceptibility to Arsenic-Induced Skin Cancer: A Cohort Study and In Silico Analysis of Mutation Impacts., International journal of molecular sciences, vol. 23(23), 14980, 2022 |
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Chien-Jen Chen*, Taiwan's pandemic vice-president - from lab bench to public office and back., Nature, vol. 603(7900), 203, 2022 |
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Chu YJ, Jeng WJ, Pan MH, Hu HH, Luo WS, Su CY, Chiang CT, Jen CL, (Chen CJ, Yang HI*, Serum soluble programmed death-1 levels predict the spontaneous HBeAg seroclearance in chronic hepatitis B., Journal of gastroenterology, vol. 57(6), 423-432, 2022 |
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Hu HH, Jeng WJ, Pan MH, Luo WS, Chang CL, Huang YT, Su CY, Chiang CT, Jen CL, Chien YC, Lu SN, Wang LY, Huang LR, Lee MH, Liu J, Nguyen MH, (Chen CJ, Yang HI*, Serum soluble programmed cell death 1 levels predict spontaneous functional cure in inactive carriers with chronic hepatitis B., Alimentary pharmacology & therapeutics, vol. 55(5), 558-567, 2022 |
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Chien LH, Chen TY, Chen CH, Chen KY, Hsiao CF, Chang GC, Tsai YH, Su WC, Huang MS, Chen YM, Chen CY, Liang SK, Chen CY, Wang CL, Hung HH, Jiang HF, Hu JW, Rothman N, Lan Q, Liu TW, (Chen CJ, Yang PC, Chang IS*, Hsiung CA*, Recalibrating Risk Prediction Models by Synthesizing Data Sources: Adapting the Lung Cancer PLCO Model for Taiwan., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol. 31(12), 2208-2218, 2022 |
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Wu HC*, Jeng WJ, Pan MH, Hsieh YC, Lu SN, (Chen CJ, Yang HI, Incidence of hepatocellular carcinoma in a community-based Taiwanese population without chronic HBV/HCV infection., JHEP reports : innovation in hepatology, vol. 4(2), 100410, 2022 |
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Coghill AE*, Fang J, Liu Z, (Chen CJ, Jarrett RF, Hjalgrim H, Proietti C, Yu KJ, Hsu WL, Lou PJ, Wang CP, Zhao Y, Doolan DL, Hildesheim A, Identifying Epstein-Barr virus peptide sequences associated with differential IgG antibody response., International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, vol. 114, 65-71, 2022 |
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Chiang CJ, Jhuang JR, Yang YW, Zhuang BZ, You SL, Lee WC*, (Chen CJ*, Association of Nationwide Hepatitis B Vaccination and Antiviral Therapy Programs With End-Stage Liver Disease Burden in Taiwan., JAMA network open, vol. 5(7), e2222367, 2022 |
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Leung CY, Huang HL, Abe SK, Saito E, Islam MR, Rahman MS, Ikeda A, Sawada N, Tamakoshi A, Gao YT, Koh WP, Shu XO, Sakata R, Tsuji I, Kim J, Park SK, Nagata C, You SL, Yuan JM, Shin MH, Pan WH, Tsugane S, Kimura T, Wen W, Cai H, Ozasa K, Matsuyama S, Kanemura S, Sugawara Y, Shin A, Wada K, (Chen CJ, Wang R, Ahn YO, Ahsan H, Boffetta P, Chia KS, Matsuo K, Qiao YL, Rothman N, Zheng W, Kang D, Inoue M*, Association of Marital Status With Total and Cause-Specific Mortality in Asia., JAMA network open, vol. 5(5), e2214181, 2022 |
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Argirion I*, Brown J, Jackson S, Pfeiffer RM, Lam TK, O'Brien TR, Yu KJ, McGlynn KA, Petrick JL, Pinto LA, (Chen CJ, Hildesheim A, Yang HI, Lee MH, Koshiol J, Association between Immunologic Markers and Cirrhosis in Individuals from a Prospective Chronic Hepatitis C Cohort., Cancers, vol. 14(21), 5280, 2022 |
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