具代表性研究發表

搜尋類別: 關鍵字搜尋: Clear
年度 論文名稱
2006 H. Qiul, A. Gabrielsen, H.E. Agardh, M. Wan, A. Wetterholm, C.-H. Wong, U. Hedin, J. Swedenborg, G.K. Hansson, B. Samuelsson, G. Paulsson-Berne, J.Z. Haeggstrom, Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlate with symptoms of plaque instability, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 103(21), 8161-8166, 2006
2006 Liang FS, Greenberg WA, Hammond JA, Hoffmann J, Head SR, Wong CH, Evaluation of RNA-binding specificity of aminoglycosides with DNA microarrays., Proceedings of the National Academy of Sciences of the United States of America, vol. 103(33), 12311-6, 2006
2006 F.-S. Liang, W. A. Greenberg, J. A. Hammond, J. Hoffmann, S. R. Head, C.-H. Wong, Evaluation of RNA Binding Specificity of Aminoglycosides with DNA Microarrays, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 103(33), 12311-12316, 2006
2006 F. S. Liang, A. Brik, Y. C. Lin, J. H. Elder, C. H. Wong, Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates, Bioorganic & medicinal chemistry, vol. 14, 1058-1062, 2006
2006 L.J. Whalen, C-H. Wong, Enzymes in Organic Synthesis: Aldolase-mediated Synthesis of Iminocyclitols and Novel Heterocycles, Aldrichimica Acta, vol. 39(3), 63-71, 2006
2006 M.G. Sanna, S.-K. Wang, P.J. Gonzalez-Cabrera, A. Don, D. Marsolais, M.P. Matheu, S.H. Wei, I. Parker, E. Jo, W.-C. Cheng, M.D. Cahalan, C.-H. Wong, H. Rosen, Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo, Nature Chemical Biology, vol. 2(8):434-441, 2006
2006 D. Wu, D.M. Zajonc, M. Fujio, B.A. Sullivan, Y. Kinjo, M. Kronenberg, I.A. Wilson, C.-H. Wong, Design of NKT-cell activators: Structure and function of a microbial glycosphingolipid bound to mouse CD1d, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 103(11), 3972-3977, 2006
2006 Wu D, Zajonc DM, Fujio M, Sullivan BA, Kinjo Y, Kronenberg M, Wilson IA, Wong CH, Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d., Proceedings of the National Academy of Sciences of the United States of America, vol. 103(11), 3972-7, 2006
2006 L. Liu, Z.-Y. Hong, C.-H. Wong, Convergent Glycopeptide Synthesis by Traceless Staudinger Ligation and Enzymatic Coupling, Chembiochem, vol. 7, 429-432, 2006
2006 M. Brigl, P. van den Elzen, X. Chen, J. H. Meyers, D. Wu, C. H. Wong, F. Reddington, P. A. Illarianov, G. S. Besra, M. B. Brenner, J. E. Gumperz, Conserved and Heterogeneous Lipid Antigen Specificities of CD1d-Restricted NKT Cell Receptors, J Immunol, vol. 176, 3625-3634, 2006
2006 Liu H, Wong CH, Characterization of a transglycosylase domain of Streptococcus pneumoniae PBP1b., Bioorganic & medicinal chemistry, vol. 14(21), 7187-95, 2006
2006 H. Liu, C.-H. Wong, Characterization of a transglycosylase domain of Streptococcus pneumoniae PBP1b, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 14, 7187-7195, 2006
2006 C. Y. Huang, D. A. Thayer, A. Y. Chang, M. D. Best, J. Hoffman, S. Head, C. H. Wong, Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen, Proceedings of the national academy of sciences of the united states of america, vol. 103, 15-20, 2006
2006 M. Sugiyama, L.J. Whalen, Z.-Y. Hong, W.A. Greenberg, C.-H. Wong, Borate as a Phosphate Ester Mimic in Aldolase-Catalyzed Reactions: Practical Syntheses of L-Fructose and L-Iminocyclitols, Advanced Synthesis and Catalysis, vol. 348, 2555-2559, 2006
2006 Lin YC, Brik A, de Parseval A, Tam K, Torbett BE, Wong CH, Elder JH, Altered gag polyprotein cleavage specificity of feline immunodeficiency virus/human immunodeficiency virus mutant proteases as demonstrated in a cell-based expression system., Journal of virology, vol. 80(16), 7832-43, 2006
2006 Y.-C. Lin, A. Brik, A. P., K. Tam, A. Parseval, B.E. Torbett, C.-H. Wong, J.H. Elder, Altered Gag Polyprotein Cleavage Specificity of Feline Immunodeficiency Virus/Human Immunodeficiency Virus Mutant Proteases as Demonstrated in a Cell-Based Expression System, JOURNAL OF VIROLOGY, vol. 80(16), 7832-7843, 2006
2006 H.-Y. Hsu, K.-F. Hua, Y.-C. Su, L.-C. Chu, H.-W. Chiu, C.-H. Wong, S.U-S. Yang, L. K. Chao, Alkali-soluble polysaccharides of Rhizoclonium riparium alga induces IL-1 gene expression via protein kinase signaling pathways, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 54, 3558-3565, 2006
2006 Hsu HY, Hua KF, Su YC, Chu LC, Su SC, Chiu HW, Wong CH, Chen ST, Shieh CW, Yang SS, Chen YM, Chao LK, Alkali-soluble polysaccharides of Rhizoclonium riparium alga induce IL-1 gene expression via protein kinase signaling pathways., Journal of agricultural and food chemistry, vol. 54(10), 3558-65, 2006
2006 L. Liu, C. S. Bennett, C. H. Wong, Advances in glycoprotein synthesis, Chemical communications, vol. 7, 21-33, 2006
2006 A. Brik, S. Ficht, C.-H. Wong, Strategies for the Preparation of Homogenous Glycoproteins, CURRENT OPINION IN CHEMICAL BIOLOGY, vol. 10(6):638-644., 2006
2006 M.F.Cheng, H.M.Yu, B.W.Ko, Y.Chang, T.I. Ho, Y.M.Tsai.and J.M.Fang, Practical synthesis of potential endothelin receptor antagonists of 1,4-Benzodiazepine-2,5-dione derivatives bearing substituent at the C3-, N1-, and N4-postions, ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 4, 510-518, 2006
2006 Y. S. Cheng, K. H. Lo, H. H. Hsu, Y. M. Shao, W. B. Yang, C. H. Lin, C. H. Wong, Screening for HIV protease inhibitors by protection against activity-mediated cytotoxicity in Escherichia coli, J Virol Methods, vol. 137, 82-87, 2006
2006 K. I. Lin, Y. Y. Kao, H. K. Kuo, W. B. Yang, A. Chou, H. H. Lin, A. L. Yu, C. H. Wong, Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor Blimp-1, J. Biol. Chem, vol. 281, 24111-24123, 2006
2006 Sawa M, Hsu TL, Itoh T, Sugiyama M, Hanson SR, Vogt PK, Wong CH, Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo., Proceedings of the National Academy of Sciences of the United States of America, vol. 103(33), 12371-12376, 2006
2006 Chien YC, Jan CF, Kuo HS, Chen CJ., Nationwide Hepatitis B Vaccination Program in Taiwan: Effectiveness in the 20 Years After it was Launched, EPIDEMIOLOGIC REVIEWS, vol. 28, 126-135, 2006
2006 Chang CF, Chou HT, Lin YJ, Lee SJ, Chuang JL, Chuang DT, Huang TH, Structure of the subunit binding domain and dynamics of the di-domain region from the core of human branched chain alpha-ketoacid dehydrogenase complex., The Journal of biological chemistry, vol. 281(38), 28345-53, 2006
2006 K. P. Wu, J. M. Chang, J. B. Chen, (C. F. Chang, W. J. Wu, T. H. Huang, T. Y. Sung, W. L. Hsu, RIBRA - An Error-Tolerant Algorithm for the NMR Backbone Assignment Problem, J Comput Biol, vol. 13, 229-244, 2006
2006 C. F. Chang)*, F. K. Shi, Y. Y. Wu, Introduction of Recent Advance in NMR Technology and Application, Instrument Today, vol. 27, 61-67, 2006
2006 K. W. Hung, Y. C. Lin, C. C. Cheng, P. J. Fang, (C. F. Chang, S. F. Tasi, T. H. Huang, Resonance assignments of a CoA binding protein from Klebsiella pneumoniae, J Biomol NMR, vol. 36 Suppl 1, 74, 2006
2006 Chen CJ, (Yang HI, Su J, Jen CL, You SL, Lu SN, Huang GT, Iloeje UH, Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level., JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, vol. 295(1), 65-73, 2006
2006 Iloeje UH, (Yang HI, Su J, Jen CL, You SL, Chen CJ, Predicting cirrhosis risk based on the level of circulating hepatitis B viral load., GASTROENTEROLOGY, vol. 130(3), 678-686, 2006
2006 S.-T. Tsai, C.-W. Chen, L.-C. Huang, M.-C. Huang, C.-H. Chen, Y.-S. Wang, Simultaneous mass analysis of positive and negative ions using a dual-polarity time-of-flight mass spectrometer, Analytical Chemistry, vol. 78 (22), 7729-7734., 2006
2006 Z. D. Burke, (C. N. Shen, K. L. Ralphs, D. Tosh, Characterization of liver function in transdifferentiated hepatocytes, Journal of cellular physiology, vol. 206(1), 147-159, 2006
2006 Chang Y, Lee HH, Chen YT, (Lu J, Wu SY, Chen CW, Takada K, Tsai CH, Induction of the early growth response 1 gene by Epstein-Barr virus lytic transactivator Zta, J Virol, vol. 80, 7748-7755, 2006
2006 Lu J, Lin WS, Chen SY, Longnecker R, Tsai CH, Epstein-Barr virus latent membrane protein 2A enhances cell mobility in epithelial cells through syk kinase, J Biol Chem, vol. 281, 8806-8814, 2006
2006 Lu J, Hou R, Booth C J, Yang SH, Snyder M, Defined culture conditions of human embryonic stem cells, Proceedings of the national academy of sciences of the united states of america, vol. 103, 5688-5693, 2006
2006 Yin Q, Park HH, Chung JY, (Lin SC, Lo YC, da Graca LS, Jiang X, Wu H*, Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine., Molecular cell, vol. 22(2), 259-268, 2006
2006 K.I Lin*, Y.Y. Kao, H.K. Kuo, W.B. Yang, A Chou, H.H. Lin, A.L. Yu, C.H.Wong, Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor blimp-1, J. Biol. Chem, vol. 281, 24111-24123, 2006
2006 F. Huang, S. F. Haydock, D. Spiteller, T. Mironenko, T. L. Li, P. F. Leadlay, D. O'Hagan, J. B. Spencer*, The gene cluster for fluorometabolite biosynthesis in Streptomyces cattleya: a thioesterase confers resistance to fluoroacetyl-coenzyme A., CELL CHEMICAL BIOLOGY (CHEMISTRY & BIOLOGY), vol. 13(5), 475-484, 2006
2006 J. Y. Ho, Y. T. Huang, C. J. Wu, Y. S. Li, M. D. Tsai, T. L. Li*, Glycopeptide Biosynthesis: Dbv21/Orf2* from dbv/tcp Gene Clusters Are N-Ac-Glm Teicoplanin Pseudoaglycone Deacetylases and Orf15 from cep Gene Cluster Is a Glc-1-P Thymidyltransferase, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 128(42), 13694-13695, 2006
2006 C. J. Wu*, T. L. Li, H. W. Huang, Y. L. Chan, M. H. Tao, Development of an effective Japanese encephalitis virus-specific DNA vaccine, MICROBES AND INFECTION, vol. 8, 2578-2586, 2006
2006 Chiou SH, Yang YP, Lin JC, Hsu CH, Jhang HC, Yang YT, Lee CH, Ho LL, Hsu WM, Ku HH, Chen SJ, Chen SS, Chang MD, Wu CW*, (Juan LJ)*, The immediate early 2 protein of human cytomegalovirus (HCMV) mediates the apoptotic control in HCMV retinitis through up-regulation of the cellular FLICE-inhibitory protein expression., Journal of immunology (Baltimore, Md. : 1950), vol. 177(9), 6199-206, 2006
2006 Maeda, Y.*, (Hwang-Verslues, W.W.)*, Wei, G., Fukazawa, T., Durbin, M.L., Owen, L. B., Liu, X., Sladek, F.M., Tumor suppressor p53 down regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4a) gene, BIOCHEMICAL JOURNAL, vol. 400(2), 303-313, 2006
2006 Lu, L.-D.; Shie, C.-R.; Kulkarni, S. S.; Pan, G.-R.; Lu, X.-A.; Hung, S.-C., Synthesis of 48 Disaccharide Building Blocks for the Assembly of a Heparin and Heparan Sulfate Oligosaccharide Library, Org. Lett, vol. 8, 5995–5998, 2006
2006 Luo, S.-Y.; Kulkarni, S. S.; Chou, C.-H.; Liao, W.-M.; Hung, S.-C., A Concise Synthesis of Tetrahydroxy-LCB, -Galactosyl Ceramide, and 1,4-Dideoxy-1,4-imino-L-ribitol via D-Allosamines as Key Building Blocks, J. Org. Chem., vol. 71, 1226–1229, 2006
2006 Lee, J.-C.; Pan, G.-R.; Kulkarni, S. S.; Luo, S.-Y.; Liao, C.-C.; Hung, S.-C., 2-Allyloxyphenyl Glycoside as a New and Stable Type of Glycosyl Donors, Tetrahedron Lett., vol. 47, 1621–1624, 2006
2006 F. C. Chen, T. J. Chuang*, The effects of multiple features of alternatively spliced exons on the Ka/Ks ratio test, BMC Bioinformatics, vol. 7, 259, 2006
2006 F. C. Chen, C. J. Chen, J. Y. Ho, T. J. Chuang*, Identification and evolutionary analysis of novel exons and alternative splicing events using cross-species EST-to-genome comparisons in human, mouse and rat, BMC Bioinformatics, vol. 7, 136, 2006
2006 F. C. Chen, S. S. Wang, C. J. Chen, W. H. Li, T. J. Chuang*, Alternatively and Constitutively Spliced Exons Are Subject to Different Evolutionary Forces, Mol Biol Evol, vol. 23, 675-682 (impact factor: 10.353; ranking: 14/290: BIOCHEMISTRY & MOLECULAR BIOLOGY), 2006
2006 Yun-Ru Chen, A. Clay Clark*, Substitutions of prolines examine their role in kinetic trap formation of the caspase recruitment domain (CARD) of RICK, Protein Science, vol. 15, 395-409, 2006
2006 Yun-Ru Chen, Charles G. Glabe*, Distinct Early Folding and Aggregation Properties of Alzheimer Amyloid-b Peptide Aβ40 and Aβ42: Stable Trimer or Tetramer Formation by Ab42, J Biol. Chem, vol. 281, 24414-24422, 2006
2006 S. N. Lu, W. W. Su, S. S. Yang, T. T. Chang, K. S. Cheng, J. C. Wu, H. H. Lin, S. S. Wu, C. M. Lee, C. S. Changchien, C. J. Chen, J. C. Sheu, D. S. Chen, C. H. Chen, Secular trends and geographic variations of hepatitis B virus and hepatitis C virus-associated hepatocellular carcinoma in Taiwan, Int J Cancer, vol. 119, 1946-1952, 2006
2006 C. J. Chen, H. I. Yang, J. Su, C. L. Jen, S. L. You, S. N. Lu, G. T. Huang, U. H. Iloeje, Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level, JAMA, vol. 295, 65-73, 2006
2006 L. C. Hwang, C. H. Bai, C. J. Chen, Prevalence of obesity and metabolic syndrome in Taiwan, J Formos Med Assoc, vol. 105, 626-635, 2006
2006 U. H. Iloeje, H. I. Yang, J. Su, C. L. Jen, S. L. You, C. J. Chen, Predicting cirrhosis risk based on the level of circulating hepatitis B viral load, Gastroenterology, vol. 130, 678-686, 2006
2006 K. H. Hsu, P. Brandt-Rauf, T. M. Lin, H. Y. Chiou, C. H. Tseng, C. J. Chen, J. J. Luo, Plasma transforming growth factor-alpha expression in residents of an arseniasis area in Taiwan, Biomarkers, vol. 11, 538-546, 2006
2006 C. C. Yeh, S. L. You, C. J. Chen, F. C. Sung, Peanut consumption and reduced risk of colorectal cancer in women: a prospective study in Taiwan, World J Gastroenterol, vol. 12, 222-227, 2006
2006 Y. C. Chien, C. F. Jan, H. S. Kuo, C. J. Chen, Nationwide hepatitis B vaccination program in Taiwan: Effectiveness in 20 years after it was launched, Epidemiol Rev, vol. 28, 126-135, 2006
2006 C. H. Chen, W. W. Su, S. S. Yang, T. T. Chang, K. S. Cheng, H. H. Lin, S. S. Wu, C. M. Lee, C. S. Changchien, C. J. Chen, J. C. Sheu, D. S. Chen, S. N. Lu, Long-term trends and geographic variations in the survival of patients with hepatocellular carcinoma: Analysis of 11,312 patients in Taiwan, J Gastroenterol Hepatol, vol. 21, 1561-1566, 2006
2006 W. L. Shih, M. W. Yu, P. J. Chen, S. H. Yeh, M. T. Lo, H. C. Chang, Y. F. Liaw, S. M. Lin, C. J. Liu, S. D. Lee, C. L. Lin, C. K. Hsiao, S. Y. Yang, C. J. Chen, Localization of a susceptibility locus for hepatocellular carcinoma to chromosome 4q in a hepatitis B hyperendemic area, Oncogene, vol. 25, 3219-3224, 2006
2006 C. Y. Wu, M. S. Wu, Y. J. Chen, C. J. Chen, J. T. Lin, G. H. Chen, Influence of COX-2 and local cytokine expression in gastric ulcer mucosa by H. pylori and NSAID, Hepatogastroenterology, vol. 53, 797-803, 2006
2006 M. H. Wu, Y. C. Chou, J. C. Yu, C. P. Yu, C. C. Wu, C. M. Chu, T. Yang, C. H. Lai, C. Y. Hsieh, S. L. You, C. J. Chen, C. A. Sun, Hormonal and body-size factors in relation to breast cancer risk: A prospective study of 11,889 women in a low-incidence area, Ann Epidemiol, vol. 16, 223-229, 2006
2006 S. Sengupta, J. A. den Boon, I. H. Chen, M. A. Newton, D. B. Dahl, M. Chen, Y. J. Cheng, W. H. Westra, C. J. Chen, A. Hildesheim, B. Sugden, P. Ahlquist, Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma, Cancer Res, vol. 66, 7999-8006, 2006
2006 L. E. Dodd, S. Sengupta, I. H. Chen, J. A. den Boon, Y. J. Cheng, M. Chen, W. Westra, M. Newton, B. F. Mittl, L. McShane, C. J. Chen, P. Ahlquist, A. Hildesheim, Genes involved in DNA repair and nitrosamine metabolism and those located on chromosome 14q32 are dysregulated in nasopharyngeal carcinoma, Cancer Epidemiol Biomarkers Prev, vol. 15, 2216-2225, 2006
2006 M. M. Wu, H. Y. Chiou, Y. M. Hsueh, C. T. Hong, C. L. Su, S. F. Chang, W. L. Huang, H. T. Wang, Y. H. Wang, Y. C. Hsieh, C. J. Chen, Effect of plasma homocysteine level and urinary monomethylarsonic acid on the risk of arsenic-related carotid atherosclerosis, Toxicol Appl Pharmacol, vol. 216, 168-175, 2006
2006 C. H. Chen, T. T. Chang, K. S. Cheng, W. W. Su, S. S. Yang, H. H. Lin, S. S. Wu, C. M. Lee, C. S. Changchien, C. J. Chen, J. C. Sheu, D. S. Chen, S. N. Lu, Do young hepatocellular carcinoma patients have worse prognosis? The paradox of age as a prognostic factor in the survival of hepatocellular carcinoma patients, Liver Int, vol. 26, 766-773, 2006
2006 X. Yang, A. M. Goldstein, C. J. Chen, C. S. Rabkin, J. Y. Chen, Y. J. Cheng, W. L. Hsu, S. R. Diehl, M. Y. Liu, M. Walters, W. Shaso, B. A. Ortiz-Conde, D. Whitby, S. H. Elmore, M. L. Gulley, A. Hildesheim, Distribution of Epstein-Barr viral load in serum of individuals from nasopharyngeal carcinoma high-risk families in Taiwan, Int J Cancer, vol. 118, 780-784, 2006
2006 U. H. Iloeje, H. I. Yang, C. J. Chen, Disease progression of chronic hepatitis B virus infection: Effects of sustained viral replication, Chinese Hepatology, vol. 11, 410-412, 2006
2006 K. H. Morales, J. G. Ibrahim, C. J. Chen, L. M. Ryan, Bayesian model averaging with applications to benchmark dose estimation for arsenic in drinking water, Journal of the American Statistical Association, vol. 101, 9-17, 2006
2006 H. P. Tseng, Y. H. Wang, M. M. Wu, H. W. The, H. Y. Chiou, C. J. Chen, Association between chronic exposure to arsenic and slow nerve conduction velocity among adolescents in Taiwan, J Health Popul Nutr, vol. 24, 182-189, 2006
2006 C. F. Jan, C. J. Chen, Y. H. Chiu, L. S. Chen, H. M. Wu, C. C. Huang, M. F. Yen, T. H. Chen, A population-based study investigating the association between metabolic syndrome and hepatitis B/C infection (Keelung Community-based Integrated Screening Study No. 10), Int J Obes, vol. 30, 794-799, 2006
2006 Fehmida Kapadia, Annie Pryor, Lee F. Johnson*, Nuclear localization of poly(A)+ mRNA following siRNA reduction of expression of the mammalian RNA helicases UAP56 and URH49, Gene, vol. 384, 37-44, 2006
2005 Cheung EC, Melanson-Drapeau L, Cregan SP, Vanderluit JL, Ferguson KL, McIntosh WC, Park DS, Bennett SA, Slack RS, Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms., The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 25(6), 1324-34, 2005
2005 Jun Li, Ying-Chih Chang*, Preparation of End-Grafted Polymer Brushes by Nitroxide-Mediated Free Radical Polymerization of Vaporized Vinyl Monomers, LANGMUIR, vol. 21, 9562-9567, 2005
2005 L. R. Chen, Y. C. Wang, Y. W. Lin, S. Y. Chou, S. F. Chen, L. T. Liu, C. J. Kuo, T. S. Chen, S. H. Juang, Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors, Bioorg Med Chem Lett, vol. 15, 3058-3062, 2005
2005 J. J. Shie, J. M. Fang, T.H. Kuo, C. J. Kuo, P. H. Liang, H. J. Huang, J.T. Jan, Y. S. Cheng, C. H. Wong, Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 13, 5240-5252, 2005
2005 Shie, J. J., Fang, J. M., Kuo, C. J., Kuo, T. H., Liang, P. H., Huang, H. J., Yang, W. B., Lin, C. H., Chen, J. L., Wu, Y. T., Wong, C. H., Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease., J Med Chem, vol. 48(13), 4469-4473, 2005
2005 Chun-Ping Lu, Yi-Ning Lai, S.-H. Wu, Wei-Man Wang, Jean-Yin Chen, Lee-Chiang Lo, Design of a Mechanism-Based Probe for Neuraminidase to Capture Influenza Viruses, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 44, 6888-6892, 2005
2005 An-Tai Wu, Yi-Ping Yu, Wei Zou, S.-H. Wu, 9-O-Sulfation on α-NeuAc-(2-8)-NeuAc and inter-residue lactonization, CARBOHYDRATE RESEARCH, vol. 340, 1219-1223, 2005
2005 Chen AY, Shih SJ, Garriques LN, Rothenberg ML, (Hsiao M, Curran DP, Silatecan DB-67 is a novel DNA topoisomerase I-targeted radiation sensitizer, Mol Cancer Ther, vol. 4, 317-324. Cite 10, 2005
2005 C. Y. Wu, A. Brik, S. K. Wang, Y. H. Chen, C. H. Wong, Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ, Chembiochem, vol. 6, 2176-2180, 2005
2005 Brik, A., Wu, C. Y., Best, M. D., Wong, C. H., Tetrabutylammonium fluoride-assisted rapid N(9)-alkylation on purine ring: Application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ., Bioorganic & medicinal chemistry, vol. 13(15), 4622-4626, 2005
2005 G. T. Fan, Y. S. Pan. K. C. Lu, Y. P. Cheng, W. C. Lin, S. Lin, S. H. Lin, C. H. Wong, J. M. Fang, C. C. Lin Wong, C. H., Fang, J. M., C. C. Lin, Synthesis of alpha-galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes., Tetrahedron, vol. 61, 1855-1862, 2005
2005 G. T. Fan, Y. S. Pan. K. C. Lu, Y. P. Cheng, W. C. Lin, S. Lin, S. H. Lin, C. H. Wong, J. M. Fang, C. C. Lin, Synthesis of ?galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes, Tetrahedron, vol. 61, 1855-1862, 2005
2005 G. W. Xing, D. Wu, M. A. Poles, A. Horowitz, M. Tsuji, D. D. Ho, C. H. Wong, Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides, Bioorganic & medicinal chemistry, vol. 13, 2907-2916, 2005
2005 Zajonc DM, Maricic I, Wu D, Halder R, Roy K, Wong CH, Kumar V, Wilson IA, Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity., The Journal of experimental medicine, vol. 202(11), 1517-26, 2005
2005 S. H. Wei, H. Rosen, M. P. Matheu, M. G. Sanna, S. K. Wang, E. Jo, C. H. Wong, I. Parker, M. D. Cahalan, Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses, Nat Immunol, vol. 6, 1228-1235, 2005
2005 Y. Kinjo, D. Wu, G. Kim, G. W. Xing, M. A. Poles, D. D. Ho, M. Tsuji, K. Kawahara, C. H. Wong, M. Kronenberg, Recognition of bacterial glycosphingolipids by natural killer T cells, Nature, vol. 434, 520-525, 2005
2005 Sinchaikul, S., Pan, F. M., Cheng, C. W., Wong, C. H., Fang, J. M., Tseng, M. J., Chen, S. T., Protein microarray using alpha-amino acids as metal tags on chips., Bioorg Med Chem Lett, vol. 15(5), 1413-1416, 2005
2005 C. H. Wong, Protein glycosylation: new challenges and opportunities, J Org Chem, vol. 70, 4219-4225, 2005
2005 J. J. Shie, J. M. Fang, T. H. Kuo, C. J. Kuo, P. H. Liang, H. J. Huang, Y. T. Wu, J. T. Jan, Y. S.E. Cheng, C. H. Wong, Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters., Bioorganic & medicinal chemistry, vol. 13, 5240–5252, 2005
2005 M. M. Numa, L. V. Lee, C. C. Hsu, K. E. Bower, C. H. Wong, Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ, Chembiochem, vol. 6, 1002-1006, 2005
2005 Sawkar AR, Adamski-Werner SL, Cheng WC, Wong CH, Beutler E, Zimmer KP, Kelly JW, Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles., Chemistry & biology, vol. 12(11), 1235-44, 2005
2005 A.R. Sawkar, S.L. Adamski-Werner, W.-C. Cheng, C.-H. Wong, E. Beutler, K.-P. Zimmer, J.W. Kelly, Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles, Chem. Biol, vol. 12(11), 1235–1244, 2005
2005 M. Fridman, V. Belakhov, L. V. Lee, F. S. Liang, C. H. Wong, T. Baasov, Dual effect of synthetic aminoglycosides: antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor, Angewandte chemie-international edition, vol. 44, 447-452, 2005
2005 D. A. Calarese, H. K. Lee, C. Y. Huang, M. D. Best, R. D. Astronomo, R. L. Stanfield, H. Katinger, D. R. Burton, C. H. Wong, I. A. Wilson, Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 13372–13377, 2005
2005 J. J. Shie, J. M. Fang, C. J. Kuo, T. H. Kuo, P. H. Liang, H. J. Huang, W. B. Yang, C. H. Lin, J. L. Chen, Y. T. Wu, C. H. Wong, Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease, J Med Chem, vol. 48, 4469-4473, 2005
2005 C.-C. Hsu, Y. Zhang, M. Wada, D. Franke, C.-H. Wong, Directed evolution of d-sialic acid aldolase l-3-deoxy-manno-2-octulosonic acid (l-KDO) aldolases, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 9122-9126, 2005
2005 C. C. Hsu, Y. Zhang, M. Wada, D. Franke, C. H. Wong, Directed evolution of D-sialic acid aldolase L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolases, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 9122–9126, 2005
2005 D. Wu, G. W. Xing, M. A. Poles, A. Horowitz, Y. Kinjo, B. Sullivan, V. Bodmer Narkevitch, O. Plettenburg, M. Kronenberg, M. Tsuji, D. D. Ho, C. H. Wong, Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 1351-1356, 2005