具代表性研究發表

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年度 論文名稱
2016 Chang WF, Hwu YM, Xu J, Lin CJ, Wang SW, Cheng AS, (Lu J, Lu CH, Sung LY, Derivation of Patient Specific Pluripotent Stem Cells Using Clinically Discarded Cumulus Cells., PloS one, vol. 11(11), e0165715, 2016
2016 Yu, Y.-H., Lin, K.-I)*, Factors that regulate the generation of antibody-secreting plasma cells., Advances in Immunology, vol. 131, 61-99, 2016
2016 Hung, K.-H., Su, S.-T., Chen, C.-Y., Hsu, P.-H., Huang, S.-Y., Wu, W.-J., Chen, M.M., Chen, H.-Y., Wu, P.-C., Lin, F.-R., Tsai, M.-D., Lin, K.-I)*, Aiolos collaborates with Blimp-1 to regulate the survival of multiple myeloma cells, CELL DEATH AND DIFFERENTIATION, vol. 23, 1175-1184, 2016
2016 Wu, J.-L., Wu, H.-Y., Tsai, D.-Y., Chiang, M.-F., Chen, Y.-J., Gao, S., Lin, C.-C., Lin, C.-H., Khoo, K.-H., Chen, Y.-J.*, Lin, K.-I )*, Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells, Nature Communications, vol. 7, 12526, 2016
2016 Chien, C.-Y., Lee, H.-S. Lee, Cho, C.H.H., (Lin, K.-I, Tosh, D., Wu, R.-R., Mao, W.-Y., Shen, C.-N., Maternal Vitamin A deficiency during pregnancy affects vascularized islet development, Journal of Nutritional Biochemistry, vol. 36, 51-59, 2016
2016 Chen, T.-T., Tsai, M.-H., Kung, J.T., (Lin, K.-I, Decker, T., Lee, C.-K., STAT1 regulates marginal zone B cell differentiation in response to inflammation and infection with blood-borne bacteria, Journal of Experimental Medicine, vol. 213, 3025-3039, 2016
2016 H. J. Chai, C. J. Wu, S. H. Yang, T. L. Li, P. B. Sun*, Peptides from hydrolysate of lantern fish (Benthosema pterotum) proved neuroprotective in vitro and in vivo, JOURNAL OF FUNCTIONAL FOODS, vol. 24, 438-449, 2016
2016 L. J. Hsu, N. S. Hsu, Y. L. Wang, C. J. Wu, T. L. Li*, Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality, PROTEIN ENGINEERING DESIGN & SELECTION, vol. 29(11), 513-522, 2016
2016 Cheung, S.K.C., Chuang, P.-K., Huang, H.-W., (Hwang-Verslues, W.W., Cho C.H.-H., Yang, W.-B., Shen, C.-N., Hsiao, M., Hsu, T.-L., Chang, C.-F., Wong, C.-H., Stage-Specific Embryonic Antigen-3 (SSEA-3) and β3GalT5 are Cancer Specific and Significant Markers for Breast Cancer Stem Cells, Proceedings of the National Academy of Sciences of the United States of America, vol. 113(4), 960-965, 2016
2016 Ho, G.-M.; Huang, C.-J., Li, E. Y.-T.*, Hsu, S.-K.; Wu, T.; Zulueta, M. M. L.; Wu, K. P.-C.; (Hung, S.-C.*, Unconventional exo-Selectivity in Thermal Normal-Electron-Demand Diels–Alder Reactions, Sci. Rep, vol. 6, 35147, 2016
2016 Liang, W. G.; Huang, T.-Y.; Zulueta, M. M. L.; (Hung, S.-C.*); Tang, W.-J.*, Structural Basis for Oligomerization and Glycosaminoglycan-Binding of CCL5 and CCL3, Proc. Natl. Acad. Sci. USA, vol. 113, 5000-5005, 2016
2016 Stewart, K. L.; Hughes, E.; Yates, E. A.; Huang, T.-Y.; Lima, M. A.; Rudd, T. R.; Guerrini, M.; (Hung, S.-C.*); Radford, S. E.*; Middleton, D. A.*, Atomic Details of the Interactions of Glycosaminoglycans with Amyloid-β Fibrils, J. Am. Chem. Soc., vol. 138, 8328-8331, 2016
2016 Chen CY, Hung LY, Wu CS, (Chuang TJ*, Purifying selection shapes the coincident SNP distribution of primate coding sequences., Scientific reports, vol. 6, 27272, 2016
2016 Trees-Juen Chuang*, Chan-Shuo Wu, Chia-Ying Chen, Li-Yang Hung, Tai-Wei Chiang, Min-Yu Yang, NCLscan: accurate identification of non-co-linear transcripts (fusion, trans-splicing, and circular RNA) with a good balance between sensitivity and precision, NUCLEIC ACIDS RESEARCH, vol. 44, e29. (Corresponding & first author; SCI impact factor: 10.162; Rank (BIOCHEMISTRY & MOLECULAR BIOLOGY): 14/286; Q1), 2016
2016 Chen KT, Chen PT, Lin CK, Huang LY, Hu CM, Chang YF, Hsu HT, Cheng TJ, Wu YT, Cheng WC, Structural Investigation of Park's Nucleotide on Bacterial Translocase MraY: Discovery of Unexpected MraY Inhibitors., Scientific reports, vol. 6, 31579, 2016
2016 Lin CK, Hou CC, Guo YY, Cheng WC, Design and Synthesis of Orthogonally Protected d- and l-beta-Hydroxyenduracididines from d-lyxono-1,4-Lactone., Organic letters, vol. 18(20), 5216-5219, 2016
2016 Cheng WC, Wang JH, Li HY, Lu SJ, Hu JM, Yun WY, Chiu CH, Yang WB, Chien YH, Hwu WL, Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency., European journal of medicinal chemistry, vol. 123, 14-20, 2016
2016 Lin CK, Yun WY, Lin LT, Cheng WC, A concise approach to the synthesis of the unique N-mannosyl d-beta-hydroxyenduracididine moiety in the mannopeptimycin series of natural products., Organic & biomolecular chemistry, vol. 14(17), 4054-4060, 2016
2016 Chia‑Wei Lee, Lan‑Ling Jang, Huei‑Jyuan Pan, (Yun‑Ru Chen, Chih‑Cheng Chen, Chau‑Hwang Lee*, Membrane roughness as a sensitive parameter reflecting the status of neuronal cells in response to chemical and nanoparticle treatments, Journal of Nanobiotechnology, vol. 14, 9, 2016
2016 Yu-Jen Chang, U-Ser Jeng, Ya-Ling Chiang, Ing-Shouh Hwang, Yun-Ru Chen)*, Glycine-Alanine Dipeptide Repeat from C9orf72 Hexanucleotide Expansions Forms Toxic Amyloids Possessing Cell-to-cell Transmission Property, Journal of Biological Chemistry, vol. 291(10), 4903-4911, 2016
2016 Yu-Jen Chang, Nguyen Hoang Linh, Hui-Ming Yu, Mai Suan Li*, Yun-Ru Chen)*, Alzheimer’s Amyloid-β Sequesters Caspase-3 in vitro via its C-terminal Tail., ACS Chemical Neuroscience, vol. 7(8), 1097-1106, 2016
2016 Nguyen Quoc Thai, Ning-Hsuan Tseng, Mui Thi Vu, Tin Trung Nguyen, Huynh Quang Linh, Chin-Kun Hu*, (Yun-Ru Chen)*, Mai Suan Li*, Discovery of DNA dyes Hoechst 34580 and 33342 as good candidates for Alzheimer’s disease: in silico and in vitro study, JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, vol. 30(8), 639-50, 2016
2016 Smethurst, Phillip*; Newcombe, Jia; Troakes, Claire;Simone, Roberto; Wadsworth, John; Hardy, John; (Chen, Yun-Ru); Patani, Rickie; Sidle, Katie, In vitro prion-like mechanisms of TDP-43 in ALS, NEUROBIOLOGY OF DISEASE, vol. 96, 236-247, 2016
2016 Tania M. Guardado-Alvarez, Wei Chen, Amie E. Norton, Melissa M. Russell, William B. Connick*, Jeffrey I. Zink*, Analyte-responsive Gated Hollow Mesoporous Silica Nanoparticles Exhibiting Inverse Functionality and an AND Logic Response, Nanoscale, vol. 8, 18296-18300, 2016
2016 NCD Risk Factor Collaboration (NCD-RisC, Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants., Lancet (London, England), vol. 387(10027), 1513-1530, 2016
2016 Hu HH, Liu J, Lin YL, Luo WS, Chu YJ, Chang CL, Jen CL, Lee MH, Lu SN, Wang LY, You SL, Yang HI, (Chen CJ, The rs2296651 (S267F) variant on NTCP (SLC10A1) is inversely associated with chronic hepatitis B and progression to cirrhosis and hepatocellular carcinoma in patients with chronic hepatitis B., Gut, vol. 65(9), 1514-1521, 2016
2016 Liu J, Yang HI, Lee MH, Jen CL, Batrla-Utermann R, Lu SN, Wang LY, You SL, (Chen CJ, Serum Levels of Hepatitis B Surface Antigen and DNA Can Predict Inactive Carriers With Low Risk of Disease Progression., Hepatology (Baltimore, Md.), vol. 64(2), 381-389, 2016
2016 Chien J, Liu J, Lee MH, Jen CL, Batrla-Utermann R, Lu SN, Wang LY, You SL, Yang HI, (Chen CJ, Risk and predictors of hepatocellular carcinoma for chronic hepatitis B patients with newly developed cirrhosis., Journal of gastroenterology and hepatology, vol. 31(12), 1971-1977, 2016
2016 Lin D, Yang HI, Nguyen N, Hoang J, Kim Y, Vu V, Le A, Chaung K, Nguyen V, Trinh H, Li J, Zhang J, Hsing A, (Chen CJ, Nguyen MH, Reduction of chronic hepatitis B-related hepatocellular carcinoma with anti-viral therapy, including low risk patients., Alimentary pharmacology & therapeutics, vol. 44(8), 846-855, 2016
2016 Poh Z, Shen L, Yang HI, Seto WK, Wong VW, Lin CY, Goh BB, Chang PE, Chan HL, Yuen MF, (Chen CJ, Tan CK, Real-world risk score for hepatocellular carcinoma (RWS-HCC): a clinically practical risk predictor for HCC in chronic hepatitis B., GUT, vol. 65(5), 887-894, 2016
2016 Chen YC, Hsiao CJ, Jung CC, Hu HH, Chen JH, Lee WC, Chiou JM, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, (Chen CJ, Yang HI, Performance Metrics for Selecting Single Nucleotide Polymorphisms in Late-onset Alzheimer's Disease., Scientific reports, vol. 6, 36155, 2016
2016 Lo YL, Pan WH, Hsu WL, Chien YC, Chen JY, Hsu MM, Lou PJ, Chen IH, Hildesheim A, (Chen CJ, Partial Least Square Discriminant Analysis Discovered a Dietary Pattern Inversely Associated with Nasopharyngeal Carcinoma Risk., PloS one, vol. 11(6), e0155892, 2016
2016 Wang Z, Seow WJ, Shiraishi K, Hsiung CA, Matsuo K, Liu J, Chen K, Yamji T, Yang Y, Chang IS, Wu C, Hong YC, Burdett L, Wyatt K, Chung CC, Li SA, Yeager M, Hutchinson A, Hu W, Caporaso N, Landi MT, Chatterjee N, Song M, Fraumeni JF Jr, Kohno T, Yokota J, Kunitoh H, Ashikawa K, Momozawa Y, Daigo Y, Mitsudomi T, Yatabe Y, Hida T, Hu Z, Dai J, Ma H, Jin G, Song B, Wang Z, Cheng S, Yin Z, Li X, Ren Y, Guan P, Chang J, Tan W, (Chen CJ, Chang GC, Tsai YH, Su WC, Chen KY, Huang MS, Chen YM, Zheng H, Li H, Cui P, Guo H, Xu P, Liu L, Iwasaki M, Shimazu T, Tsugane S, Zhu J, Jiang G, Fei K, Park JY, Kim YH, Sung JS, Park KH, Kim YT, Jung YJ, Kang CH, Park IK, Kim HN, Jeon HS, Choi JE, Choi YY, Kim JH, Oh IJ, Kim YC, Sung SW, Kim JS, Yoon HI, Kweon SS, Shin MH, Seow A, Chen Y, Lim WY, Liu J, Wong MP, Lee VH, Bassig BA, Tucker M, Berndt SI, Chow WH, Ji BT, Wang J, Xu J, Sihoe AD, Ho JC, Chan JK, Wang JC, Lu D, Zhao X, Zhao Z, Wu J, Chen H, Jin L, Wei F, Wu G, An SJ, Zhang XC, Su J, Wu YL, Gao YT, Xiang YB, He X, Li J, Zheng W, Shu XO, Cai Q, Klein R, Pao W, Lawrence C, Hosgood HD 3rd, Hsiao CF, Chien LH, Chen YH, Chen CH, Wang WC, Chen CY, Wang CL, Yu CJ, Chen HL, Su YC, Tsai FY, Chen YS, Li YJ, Yang TY, Lin CC, Yang PC, Wu T, Lin D, Zhou B, Yu J, Shen H, Kubo M, Chanock SJ, Rothman N, Lan Q, Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women., Human molecular genetics, vol. 25(3), 620-9, 2016
2016 Huang YT, Freeman JR, Yang HI, Liu J, Lee MH, (Chen CJ, Mediation effect of hepatitis B and C on mortality., European journal of epidemiology, vol. 31(6), 625-657, 2016
2016 Huang YT*, Yang HI, Liu J, Lee MH, Freeman JR, (Chen CJ, Mediation analysis of hepatitis B and C in relation to hepatocellular carcinoma risk, EPIDEMIOLOGY, vol. Jan;27(1), 14-20, 2016
2016 Hoang JK, Yang HI, Le A, Nguyen NH, Lin D, Vu VD, Chaung K, Nguyen V, Trinh HN, Li J, Zhang JQ, (Chen CJ, Nguyen MH, Lower liver cancer risk with antiviral therapy in chronic hepatitis B patients with normal to minimally elevated ALT and no cirrhosis., Medicine, vol. 95(31), e4433, 2016
2016 Chang MH, You SL, (Chen CJ, Liu CJ, Lai MW, Wu TC, Wu SF, Lee CM, Yang SS, Chu HC, Wang TE, Chen BW, Chuang WL, Soon MS, Lin CY, Chiou ST, Kuo HS, Chen DS, Long-term Effects of Hepatitis B Immunization of Infants in Preventing Liver Cancer., Gastroenterology, vol. 151(3), 472-480.e1, 2016
2016 Yang HI, Tseng TC, Liu J, Lee MH, Liu CJ, Su TH, Batrla-Utermann R, Chan HL, Kao JH, (Chen CJ, Incorporating Serum Level of Hepatitis B Surface Antigen or Omitting Level of Hepatitis B Virus DNA Does not Affect Calculation of Risk for Hepatocellular Carcinoma in Patients Without Cirrhosis., Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 14(3), 461-468.e2, 2016
2016 Chiang CJ, Lo WC, Yang YW, You SL, (Chen CJ, Lai MS, Incidence and survival of adult cancer patients in Taiwan, 2002-2012., Journal of the Formosan Medical Association = Taiwan yi zhi, vol. 115(12), 1076-1088, 2016
2016 Coghill AE, Bu W, Nguyen H, Hsu WL, Yu KJ, Lou PJ, Wang CP, (Chen CJ, Hildesheim A, Cohen JI, High Levels of Antibody that Neutralize B-cell Infection of Epstein-Barr Virus and that Bind EBV gp350 Are Associated with a Lower Risk of Nasopharyngeal Carcinoma., Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 22(14), 3451-3457, 2016
2016 Pan WC, Wu CD, Chen MJ, Huang YT, (Chen CJ, Su HJ, Yang HI, Fine Particle Pollution, Alanine Transaminase, and Liver Cancer: A Taiwanese Prospective Cohort Study (REVEAL-HBV)., Journal of the National Cancer Institute, vol. 108(3), djv341, 2016
2016 Yang SY, Hsiung CN, Li YJ, Chang GC, Tsai YH, Chen KY, Huang MS, Su WC, Chen YM, Hsiung CA, Yang PC, (Chen CJ, Wu PE, Yu JC, Shen CY, Hsu HM, Fanconi anemia genes in lung adenocarcinoma- a pathway-wide study on cancer susceptibility., Journal of biomedical science, vol. 23, 23, 2016
2016 Hsu LI, Wang YH, Hsieh FI, Yang TY, Wen-Juei Jeng R, Liu CT, Chen CL, Hsu KH, Chiou HY, Wu MM, (Chen CJ, Effects of Arsenic in Drinking Water on Risk of Hepatitis or Cirrhosis in Persons With and Without Chronic Viral Hepatitis., Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 14(9), 1347-1355.e4, 2016
2016 Wu MM, Lee CH, Hsu LI, Cheng WF, Lee TC, Wang YH, Chiou HY, (Chen CJ, Effect of heme oxygenase-1 gene promoter polymorphism on cancer risk by histological subtype: A prospective study in arseniasis-endemic areas in Taiwan., International journal of cancer, vol. 138(8), 1875-86, 2016
2016 Chen DS, Liaw YF, (Chen CJ, Wu JC, Chuang WL, Peng CY, Chien RN, Differences in hepatitis viral etiology of hepatocellular carcinoma in Taiwan and China., Hepatology (Baltimore, Md.), vol. 64(3), 1008-1009, 2016
2016 Hsu LI, Cheng YW, (Chen CJ, Wu MM, Hsu KH, Chiou HY, Lee CH, Cumulative arsenic exposure is associated with fungal infections: Two cohort studies based on southwestern and northeastern basins in Taiwan., Environment international, vol. 96, 173-179, 2016
2016 Wu HC, Shen J, Yang HI, Tsai WY, (Chen CJ, Santella RM, Blood DNA methylation markers in prospectively identified hepatocellular carcinoma cases and controls from Taiwan., World journal of hepatology, vol. 8(5), 301-306, 2016
2016 Liu Z, Coghill AE, Pfeiffer RM, Hsu WL, Lou PJ, Wang CP, Yu KJ, Niwa S, Brotzman M, Ye W, (Chen CJ, Hildesheim A, Birth order and risk of nasopharyngeal carcinoma in multiplex families from Taiwan., International journal of cancer, vol. 139(11), 2467-2473, 2016
2016 Sarin SK, Kumar M, Lau GK, Abbas Z, Chan HLY, (Chen CJ, Chen DS, Chen HL, Chen PJ, Chien RN, Dokmeci AK, Gane Ed, Hou JL, Jafri W, Jia J, Kim JH, Lai CL, Lee HC, Lim SG, Liu CJ, Locarnini S, Mahtab M Al, Mohamed R, Omata M, Park J, Piratvisuth T, Sharma BC, Sollano J, Wang FS, Wei L, Yuen MF, Zheng SS, Kao JH, Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update, Hepatol Int, vol. 10(1), 1-98, 2016
2016 Ku WY, Liaw YP, Huang JY, Nfor ON, Hsu SY, Ko PC, Lee WC, (Chen CJ, An Online Atlas for Exploring Spatio-Temporal Patterns of Cancer Mortality (1972-2011) and Incidence (1995-2008) in Taiwan., Medicine, vol. 95(21), e3496, 2016
2016 Liu J, Yang HI, Lee MH, Jen CL, Hu HH, Lu SN, Wang LY, You SL, Huang YT, (Chen CJ, Alcohol Drinking Mediates the Association between Polymorphisms of ADH1B and ALDH2 and Hepatitis B-Related Hepatocellular Carcinoma., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol. 25(4), 693-699, 2016
2016 Bei JX, Su WH, Ng CC, Yu K, Chin YM, Lou PJ, Hsu WL, Hsu WL, McKay JD, (Chen CJ, Chang YS, Liu JJ, Zeng YX, Hildesheim A*, A GWAS meta-analysis and replication study identifies a novel locus within CLPTM1L/TERT associated with nasopharyngeal carcinoma in individuals of Chinese ancestry, Cancer Epidemiology Biomarkers & Prevention, vol. 25(1), 188-192, 2016
2016 NCD Risk Factor Collaboration (NCD-RisC, A century of trends in adult human height., eLife, vol. 5, 13410, 2016
2016 Fu-Lung Yeh, Luh Tung, Tien-Hsien Chang)*, Detection of protein-protein interaction within an RNA-protein complex via unnatural-amino-acid-mediated photochemical crosslinking, Methods in Molecular Biology, vol. 1421, 175-189, 2016
2016 Tsai, P.-W., Chien, C.-Y., Yeh, Y.-C., Tung, L., Chen, H.-F., (Chang, T.-H., Lan, C.Y., Candida albicans Hom6 is a homoserine dehydrogenase involved in protein synthesis and cell adhesion, JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, vol. 50, 863-871, 2016
2016 Lee, F. F.-Y., Hui, C.-F., (Chang, T.-H.)*, Chiou, P. P.*, Alternative Splicing of Toll-Like Receptor 9 Transcript in Teleost Fish Grouper Is Regulated by NF-κB Signaling via Phosphorylation of the C-Terminal Domain of the RPB1 Subunit of RNA Polymerase II, PLOS ONE, vol. 11(9), e0163415, 2016