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A. Brik, J. Muldoon, Y. C. Lin, J. H. Elder, D. S. Goodsell, A. J. Olson, V. V. Fokin, K. B. Sharpless, Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors, Chembiochem, vol. 4, 1246-1248, 2003 |
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E. Chapman, M. C. Bryan, Mechanistic studies of beta-arylsulfotransferase IV, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 100, 910-915, 2003 |
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A. Brik, HIV-1 protease: mechanism and drug discovery, Org Biomol Chem, vol. 1, 5-14, 2003 |
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T. J. Tolbert, Glycoprotein synthesis, In: Yearbook of Science & Technology, vol. 159-162, 2003 |
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M. Wada, C. C. Hsu, D. Franke, M. Mitchell, A. Heine, I. Wilson, Directed evolution of N-acetylneuraminic acid aldolase to catalyze enantiomeric aldol reactions, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 2091-2098, 2003 |
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C. C. Mak, A. Brik, D. L. Lerner, J. H. Elder, G. M. Morris, A. J. Olson, Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteases, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 2025-2040, 2003 |
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T. Feizi, F. Fazio, W. Chai, Carbohydrate microarrays - a new set of technologies at the frontiers of glycomics, CURRENT OPINION IN STRUCTURAL BIOLOGY, vol. 13, 637-645, 2003 |
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M. G. Silvestri, G. Desantis, M. Mitchell, Asymmetric aldol reactions using aldolases, In: Topics in Stereochemistry, Vol 23, vol. 23, 267-342, 2003 |
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H. Liu, T. K. Ritter, R. Sadamoto, P. S. Sears, M. Wu, Acceptor specificity and inhibition of the bacterial cell-wall glycosyltransferase MurG, Chembiochem, vol. 4, 603-609, 2003 |
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T. K. Ritter, K. K. Mong, H. Liu, T. Nakatani, A programmable one-pot oligosaccharide synthesis for diversifying the sugar domains of natural products: a case study of vancomycin, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 42, 4657-4660, 2003 |
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L. V. Lee, M. L. Mitchell, S. J. Huang, V. V. Fokin, K. B. Sharpless, A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry, J Am Chem Soc, vol. 125, 9588-9589, 2003 |
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T. K. Mong, C. Y. Huang, A new reactivity-based one-pot synthesis of N-acetyllactosamine oligomers, J Org Chem, vol. 68, 2135-2142, 2003 |
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H. Liu, L. Wang, A. Brock, P. G. Schultz, A method for the generation of glycoprotein mimetics, J Am Chem Soc, vol. 125, 1702-1703, 2003 |
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H. C. Lin, W. B. Yang, Y. F. Gu, C. Y. Chen, C. Y. Wu, C. H. Lin, Stereoselective glycosylation of exo-glycals accelerated by Ferrier-type rearrangement, Org Lett, vol. 5, 1087-1089, 2003 |
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Cheng YJ, Chien YC, Hildesheim A, Hsu MM, Chen IH, Chuang J, Chang J, Ma YD, Luo CT, Hsu WL, Hsu HH, Huang H, Chang JF, Chen CJ, Yang CS., No Association Between Genetic Polymorphisms of CYP1A1, GSTM1, GSTT1, GSTP1, NAT2, and Nasopharyngeal Carcinoma in Taiwan, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, vol. 12(2), 179-180, 2003 |
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Chien YC, Chen CJ., Epidemiology and Etiology of Nasopharyngeal Carcinoma: Gene-Environment Interaction, CANCER REVIEWS: ASIA-PACIFIC, vol. 1(1), 1-19, 2003 |
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Cheng TJ, Tseng YF, Chang WM, Chang MD, Lai YK, Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2., Journal of cellular biochemistry, vol. 89(3), 589-602, 2003 |
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Wang LY, You SL, Lu SN, Ho HC, Wu MH, Sun CA, (Yang HI, Chien-Jen C, Risk of hepatocellular carcinoma and habits of alcohol drinking, betel quid chewing and cigarette smoking: a cohort of 2416 HBsAg-seropositive and 9421 HBsAg-seronegative male residents in Taiwan., CANCER CAUSES & CONTROL, vol. 14(3), 241-250, 2003 |
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Shen CN, Horb ME, Slack JM, Tosh D, Transdifferentiation of pancreas to liver., Mechanisms of development, vol. 120(1), 107-16, 2003 |
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M. E. Horb, (C. N. Shen, D. Tosh, J. M. Slack, Experimental conversion of liver to pancreas, Current biology, vol. 13, 105-115, 2003 |
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Lu J, Chua HH, Chen SY, Chen JY, Tsai CH, Regulation of matrix metalloproteinase-1 by Epstein-Barr virus proteins, Cancer Res, vol. 63, 256-262, 2003 |
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Lo YC, (Lin SC, Shaw JF, Liaw YC*, Crystal structure of Escherichia coli thioesterase I/protease I/lysophospholipase L1: consensus sequence blocks constitute the catalytic center of SGNH-hydrolases through a conserved hydrogen bond network., Journal of molecular biology, vol. 330(3), 539-551, 2003 |
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K. I. Lin, C. Tunyaplin, K. Calame, Transcriptional regulatory cascades controlling plasma cell differentiation, Immunol Rev, vol. 194, 19-28, 2003 |
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K. L. Calame, K. I. Lin, C. Tunyaplin, Regulatory mechanisms that determine the development and function of plasma cells, Annu Rev Immunol, vol. 21, 205-230, 2003 |
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M. Shapiro-Shelef, K. I. Lin, L. J. McHeyzer-Williams, J. Liao, M. G. McHeyzer-Williams, K. Calame, Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells, Immunity, vol. 19, 607-620, 2003 |
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Lu, X.-A.; Chou, C.-H.; Wang, C.-C.; Hung, S.-C., Regioselective Esterification of Various D-Glucopyranosides: A Concise Synthesis of a Fully Protected Disaccharide Unit of Hyaluronic Acid, Synlett, vol. 9(S1), 1364-1366, 2003 |
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Tai, C.-A.; Kulkarni, S. S.; Hung, S.-C., Facile Cu(OTf)2-catalyzed Preparation of Per-O-acetylated Hexopyranoses with Stoichiometric Acetic Anhydride and Sequential One-pot Anomeric Substitution to Thioglycosides under Solvent-free Conditions, J. Org. Chem., vol. 68, 8719–8722, 2003 |
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Yang, W.-C.; Lu, X.-A.; Kulkarni, S. S.; Hung, S.-C., Cu(OTf)2-catalyzed Et3SiH-reductive Etherification of Various Carbonyl Compounds with Trimethylsilyl Ethers, Tetrahedron Lett., vol. 44, 7837–7840, 2003 |
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T. J. Chuang, W. C. Lin, H. C. Lee, C. W. Wang, K. L. Hsiao, Z. H. Wang, D. Shieh, S. C. Lin, L. Y. Ch'ang, A complexity reduction algorithm for analysis and annotation of large genomic sequences, Genome Res, vol. 13(2), 313-322 (impact factor: 14.397; ranking: 3/160: BIOTECHNOLOGY & APPLIED MICROBIOLOGY), 2003 |
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Yun-Ru Chen, A. Clay Clark*, Equilibrium and Kinetic Folding of the α-Helical Greek Key Protein Domain: Caspase Recruitment Domain (CARD) of RICK, Biochemistry, vol. 42, 6310-6320, 2003 |
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M. L. Lee*, C. J. Chen, I. J. Su, K. T. Chen, C. C. Yeh, C. C. King, H. L. Chang, Y. C. Wu, M. S. Ho, D. D. Jiang, W. F. Lin, H. C. Lang, T. Lin, M. H. Lai, J. T. Wang, C. H. Chen, Use of quarantine to prevent transmission of severe acute respiratory syndrome-Taiwan, MMWR Morb Mortal Wkly Rep, vol. 52, 680-683, 2003 |
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Y. L. Jeng, M. H. Wu, H. B. Huang, W. Y. Lin, S. L. You, T. Y. Chu, C. J. Chen, C. A. Sun*, The methylenetetrahydrofolate reductase 667C→T polymorphism and lung cancer risk in a Chinese population, Anticancer Res, vol. 23, 5149-5152, 2003 |
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S. Y. Tsai*, H. Y. Chiou, H. W. The, C. M. Chen, C. J. Chen, The effects of chronic arsenic exposure from drinking water on the neurobehavioral development in adolescence, Neurotoxicology, vol. 24, 747-753, 2003 |
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J. M. Lee*, Y. C. Lee, S. Y. Yang, S. P. Luh, C. J. Lee, C. J. Chen, M. T. Wu, The association of GSTT1 polymorphisms with the risk of esophageal cancer: Interactive with environmental exposure, J Genet Mol Biol, vol. 14, 41-50, 2003 |
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M. L. Lee*, C. J. Chen, I. J. Su, K. T. Chen, C. C. Yeh, C. C. King, H. L. Chang, Y. C. Wu, M. S. Ho, D. D. Jiang, D. Wong, Severe acute respiratory syndrome, Taiwan,2003, MMWR Morb Mortal Wkly Rep, vol. 52, 461-466, 2003 |
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M. W. Yu*, H. C. Chang, S. C. Chang, Y. F. Liaw, S. M. Lin, C. J. Liu, S. D. Lee, C. L. Lin, P. J. Chen, S. C. Lin, C. J. Chen, Role of reproductive factors in hepatocellular Carcinoma: Impact on hepatitis B- and C-related risk, Hepatology, vol. 38, 1393-1400, 2003 |
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R. M. Pfeiffer, A. Hildesheim, M. H. Gail, D. Pee, C. J. Chen, A. M. Goldstein*, S. R. Diehl, Robustness of inference on measured covariates to misspecification of genetic random effects in family studies, Genet Epidemiol, vol. 24, 14-23, 2003 |
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L. Y. Wang, S. L. You, S. N. Lu, H. C. Ho, M. H. Wu, C. A. Sun, H. I. Yang, C. J. Chen*, Risk of hepatocellular carcinoma and habits of alcohol drinking, betel quid chewing, and cigarette smoking: a cohort of 2416 HBsAg-seropositive and 9421 HBsAg-seronegative male residents in Taiwan, Cancer Cause Control, vol. 14, 241-250, 2003 |
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S. L. Wang*, J. M. Chiou, C. J. Chen, T. N. Wu, L. W. Chang, Prevalence of diabetes mellitus and its vascular complications in southwestern arseniasis-endemic and non-endemic areas in Taiwan, Environ Health Perspect, vol. 111, 155-159, 2003 |
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C. J. Chen*, Polyostotic Langerhans cell histiocytosis and El Nino: a Novel hypothesis (editorial), Acta Pediatr Taiwan, vol. 44, 4, 2003 |
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M. W. Yu*, S. Y. Yang, I. J. Pan, C. L. Lin, C. J. Liu, Y. F. Liaw, S. M. Lin, P. J. Chen, S. D. Lee, C. J. Chen, Polymorphisms in XRCC1 and glutathione S-transferase genes and hepatitis B-related hepatocellular carcinoma, J Natl Cancer Inst, vol. 95, 1485-1488, 2003 |
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Y. J. Cheng, Y. C. Chien, A. Hildesheim, M. M. Hsu, I. H. Chen, J. Chuang, J. Chang, C. T. Luo, Y. L. Ma, W. L. Hsu, H. X. Hsu, X. Huang, J. F. Chang, C. J. Chen*, C. S. Yang, No association between genetic polymorphisms of CYP1A1, GSTM1, GSTT1, GSTP1, and NAT2 and risk of nasopharyngeal carcinoma in Taiwan, Cancer Epidemiol Biomarkers Prev, vol. 12, 179-180, 2003 |
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E. Y. Cho, A. Hildesheim, C. J. Chen, M. M. Hsu, I. H. Chen, B. F. Mittl, P. H. Levine, M. Y. Liu, J. Y. Chen, L. A. Brinton, Y. J. Cheng*, C. S. Yang, Nasopharyngeal carcinoma and genetic polymorphisms of DNA repair enzymes XRCC1 and hOGG1, Cancer Epidemiol Biomarker Prev, vol. 12, 1100-1104, 2003 |
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C. H. Tseng*, C. K. Chong, C. P. Tseng, Y. M. Hsueh, H. Y. Chiou, C. C. Tseng, C. J. Chen, Long-term arsenic exposure and ischemic heart disease in arseniasis-hyperendemic villages in Taiwan, Toxicol Lett, vol. 137, 15-21, 2003 |
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M. S. Wu, C. Y. Wu, C. J. Chen, M. T. Lin, C. T. Shun, J. T. Lin*, Interleukin-10 genotypes associate with the risk of gastric carcinoma in Taiwanese Chinese, Int J Cancer, vol. 104, 617-623, 2003 |
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C. A. Sun*, D. M. Wu, C. C. Lin, S. N. Lu, S. L. You, L. Y. Wang, M. H. Wu, C. J. Chen, Incidence and co-factors of hepatitis C virus-related hepatocellular carcinoma: a prospective study of 12,008 men in Taiwan, Am J Epidemiol, vol. 157, 674-682, 2003 |
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Y. J. Zhang, Y. Chen, H. Ahsan, R. M. Lunn, P. H. Lee, C. J. Chen, R. M. Santella*, Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by Promoter hypermethylation and its relationship to aflatoxin B1-DNA adducts and p53 mutation in hepatocellular carcinoma, Int J Cancer, vol. 103, 440-444, 2003 |
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K. T. Chen*, C. J. Chen, E. W. Gregg, G. Imperatore, K. M. V. Narayan, Impaired fasting glucose and risk of diabetes in Taiwan: follow-up over three years, Diabetes Res Clin Pract, vol. 60, 177-182, 2003 |
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M. S. Wu, C. J. Chen, J. T. Lin*, Genetic alterations and polymorphisms in gastric cancer, J Formos Med Assoc, vol. 102, 447-458, 2003 |
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M. M. Wu, H. Y. Chiou, I. C. Ho, C. J. Chen, T. C. Lee*, Gene expression of inflammatory molecules in circulating lymphocytes from arsenic-exposed human subjects, Environ Health Perspect, vol. 111, 1429-1438, 2003 |
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C. J. Chen*, Y. C. Chien, Y. C. Chen, Evaluation of crisis management capability of public health and medical care system in Taiwan: review and perspective, Commun Develop J, vol. 104, 12-16, 2003 |
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Y. C. Chien, C. J. Chen*, Epidemiology and etiology of nasopharyngeal carcinoma: Gene-environment interaction, Cancer Rev Asia-Pacific, vol. 1, 1-19, 2003 |
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Y. M. Hsueh*, Y. F. Ko, Y. K. Huang, H. W. Chen, H. Y. Chiou, Y. L. Huang, M. H. Yang, C. J. Chen, Determination of inorganic arsenic methylation capability among residents of the Lanyang Basin, Taiwan: Arsenic and selenium exposure and alcohol consumption, Toxicol Lett, vol. 137, 49-63, 2003 |
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S. J. Twu*, T. J. Chen, C. J. Chen, S. J. Olsen, L. T. Lee, T. Fisk, K. H. Hsu, S. C. Chang, K. T. Chen, I. H. Chiang, Y. C. Wu, J. S. Wu, S. F. Dowell, Control measures for severe acute respiratory syndrome (SARS) in Taiwan, Emerg Infect Dis, vol. 9, 718-720, 2003 |
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Y. P. Liaw*, C. J. Chen, W. C. Lee, S. Y. Hsu, Construction and use of the digitized atlas of cancer mortality and incidence in Taiwan, Taiwan J Public Health, vol. 22, 227-236, 2003 |
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J. M. Lee*, Y. C. Lee, C. J. Chen, M. T. Wu, Application of genetic polymorphisms in DNA repair in the prediction of cancer susceptibility and clinical outcome, Current Pharmacogenomics, vol. 1, 175-186, 2003 |
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C. A. Sun*, C. J. Chen, Aflatoxin-induced hepatocarcinogenesis: Epidemiological evidence and mechanistic considerations, J Med Sci, vol. 23, 311-318, 2003 |
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S. S.-I Tseng-Rogenski, J.-L. Chong, C. B. Thomas, S. Enomoto, J. Berman, Functional conservation of Dhh1p, a DExD/H-box protein in Saccharomyces cerevisiae, Nucleic Acids Research, vol. 31, 4995-5002, 2003 |
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Y. Wang, Y. -C. Chang*, Grafting of Homo- Block Co-polypeptides on Solid Substrates by an Improved Surface-Initiated Vapor Deposition Polymerization, LANGMUIR, vol. 18, 9859-9866, 2002 |
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C.-S. Chen, S.-H. Wu, Synthesis of a Sialic Acid Dimer Derivative 2α-O-Benzyl Neu5Ac-α-(2-5) Neu5Gc, J. Org. Chem, vol. 67, 1376-1379, 2002 |
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P. T. Nyffeler, C. H. Liang, K. M. Koeller, The chemistry of amine-azide interconversion: catalytic diazotransfer and regioselective azide reduction, J Am Chem Soc, vol. 124, 10773-10778, 2002 |
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F. Fazio, M. C. Bryan, O. Blixt, J. C. Paulson, Synthesis of sugar arrays in microtiter plate, J Am Chem Soc, vol. 124, 14397-14402, 2002 |
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O. Plettenburg, V. Bodmer Narkevitch, Synthesis of alpha-galactosyl ceramide, a potent immunostimulatory agent, J Org Chem, vol. 67, 4559-4564, 2002 |
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M. L. Mitchell, F. Tian, L. V. Lee, Synthesis and evaluation of transition-state analogue inhibitors of alpha-1,3-fucosyltransferase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 3041-3044, 2002 |
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M. L. Mitchell, L. V. Lee, Synthesis and evaluation of six-membered GDP-iminocyclitol, Tetrahedron Lett, vol. 43, 5691-5693, 2002 |
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Y. Y. Wang, K. H. Khoo, S. T. Chen, C. C. Lin, C. H. Lin, Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 10, 1057-1062, 2002 |
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J. J. Liu, G. DeSantis, Structure-based rationalization of aldolase-catalyzed asymmetric synthesis, CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, vol. 80, 643-645, 2002 |
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T. Kanemitsu, O. Kanie, Solid-phase synthesis of oligosaccharides and on-resin quantitative monitoring using gated decoupling (13)C NMR, J Am Chem Soc, vol. 124, 3591-3599, 2002 |
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J. Liu, Selectfluor(TM)-mediated allylstannation of aldehydes and imines, Tetrahedron Lett, vol. 43, 3915-3917, 2002 |
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M. C. Bryan, O. Plettenburg, P. Sears, D. Rabuka, S. Wacowich Sgarbi, Saccharide display on microtiter plates, Chem Biol, vol. 9, 713-720, 2002 |
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Z. Zhang, Regioselective benzoylation of sugars mediated by excessive Bu2SnO: observation of temperature promoted migration, Tetrahedron, vol. 58, 6513-6519, 2002 |
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K. K. Mong, Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: a colon-rectal cancer antigen determinant, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 4087-4090, 2002 |
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O. Plettenburg, C. Mui, V. Bodmer Narkevitch, Rapid preparation of glycolipid libraries by cross metathesis, Adv Synth Catal, vol. 344, 622-626, 2002 |
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T. J. Tolbert, New methods for proteomic research: Preparation of proteins with N-terminal cysteines for labeling and conjugation, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 2171-2174, 2002 |
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F. MorisVaras, Hydroxyazepanes as inhibitors of glycosidases and HIV protease, US Patent, vol. #6,462,193, 2002 |
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M. M. Thunnissen, B. Andersson, B. Samuelsson, J. Z. Haeggstrom, Crystal structures of leukotriene A4 hydrolase in complex with captopril and two competitive tight-binding inhibitors, Faseb J, vol. 16, 1648-1650, 2002 |
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A. R. Sawkar, W. C. Cheng, E. Beutler, W. E. Balch, J. W. Kelly, Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 99, 15428-15433, 2002 |
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R. Sadamoto, K. Niikura, P. S. Sears, H. Liu, A. Suksomcheep, F. Tomita, K. Monde, S. Nishimura, Cell-wall engineering of living bacteria, J Am Chem Soc, vol. 124, 9018-9019, 2002 |
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C. T. Guo, X. L. Sun, O. Kanie, K. F. Shortridge, T. Suzuki, D. Miyamoto, K. I. Hidari, Y. Suzuki, An O-glycoside of sialic acid derivative that inhibits both hemagglutinin and sialidase activities of influenza viruses, Glycobiology, vol. 12, 183-190, 2002 |
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J. Liu, C. Y. Huang, An efficient method for the preparation of 2-hydroxy- and 2-aminoglycals from glycosyl sulfoxides, Tetrahedron Lett, vol. 43, 3447-3448, 2002 |
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J. Liu, An efficient method for the cleavage of p-methoxybenzylidene (PMP), tetrahydropyranyl (THP) and 1,3-dithiane protecting groups by Selectfluor(TM), Tetrahedron Lett, vol. 43, 4037-4039, 2002 |
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J. J. Liu, Aldolase-catalyzed asymmetric synthesis of novel pyranose synthons as a new entry to heterocycles and epothilones, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 1404-1407, 2002 |
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Z. Y. Zhang, K. Niikura, X. F. Huang, A strategy for the one-pot synthesis of sialylated oligosaccharides, CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, vol. 80, 1051-1054, 2002 |
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A. Brik, Y. C. Lin, J. Elder, A quick diversity-oriented amide-forming reaction to optimize P-subsite residues of HIV protease inhibitors, Chem Biol, vol. 9, 891-896, 2002 |
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I. Wang, S. H. Wu, H. K. Chang, R. C. Shieh, H. M. Yu, C. Chen, Solution Structure of a K-Channel Blocker from the Scorpion Tityus cambridgei, PROTEIN SCIENCE, vol. 11(2), 390-400, 2002 |
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W. B. Yang, S. S. Patil, C. H. Tsai, C. H. Lin, J.M. Fang, The synthesis of -gulose and -xylose from -gluconolactone, Tetrahedron, vol. 58, 253-259, 2002 |
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W. B. Yang, Y. Y. Yang, Y. F. Gu, S. H. Wang, C. C. Chang, C. H. Lin, Stereochemistry in the synthesis and reaction of exo-glycals, J Org Chem, vol. 67, 3773-3782, 2002 |
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Cheng TJ, Rey PG, Poon T, Kan CC, Kinetic studies of human tyrosyl-DNA phosphodiesterase, an enzyme in the topoisomerase I DNA repair pathway., European journal of biochemistry / FEBS, vol. 269(15), 3697-3704, 2002 |
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Yang HI, Lu SN, Liaw YF, You SL, Sun CA, Wang LY, Hsiao CK, Chen PJ, Chen DS, Chen CJ, Hepatitis B e antigen and the risk of hepatocellular carcinoma., NEW ENGLAND JOURNAL OF MEDICINE, vol. 347(3), 168-174, 2002 |
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