Selected Publications

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Year Paper Title
2003 C. Y. Wu, C. F. Chang, J. S. Chen, C. H. Lin, Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 42, 4661-4664, 2003
2003 A. Brik, J. Muldoon, Y. C. Lin, J. H. Elder, D. S. Goodsell, A. J. Olson, V. V. Fokin, K. B. Sharpless, Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors, Chembiochem, vol. 4, 1246-1248, 2003
2003 Programmable one-pot oligosaccharide synthesis, US Patent, vol. #6,538,117, 2003
2003 D. Franke, T. Machajewski, C. C. Hsu, One-pot synthesis of L-Fructose using coupled multienzyme systems based on rhamnulose-1-phosphate aldolase, J Org Chem, vol. 68, 6828-6831, 2003
2003 New developments in biocatalysis, Adv Synth Catal, vol. 345, 651-651, 2003
2003 E. Chapman, M. C. Bryan, Mechanistic studies of beta-arylsulfotransferase IV, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 100, 910-915, 2003
2003 A. Brik, HIV-1 protease: mechanism and drug discovery, Org Biomol Chem, vol. 1, 5-14, 2003
2003 T. J. Tolbert, Glycoprotein synthesis, In: Yearbook of Science & Technology, vol. 159-162, 2003
2003 M. Wada, C. C. Hsu, D. Franke, M. Mitchell, A. Heine, I. Wilson, Directed evolution of N-acetylneuraminic acid aldolase to catalyze enantiomeric aldol reactions, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 2091-2098, 2003
2003 C. C. Mak, A. Brik, D. L. Lerner, J. H. Elder, G. M. Morris, A. J. Olson, Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteases, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 2025-2040, 2003
2003 T. Feizi, F. Fazio, W. Chai, Carbohydrate microarrays - a new set of technologies at the frontiers of glycomics, CURRENT OPINION IN STRUCTURAL BIOLOGY, vol. 13, 637-645, 2003
2003 M. G. Silvestri, G. Desantis, M. Mitchell, Asymmetric aldol reactions using aldolases, In: Topics in Stereochemistry, Vol 23, vol. 23, 267-342, 2003
2003 H. Liu, T. K. Ritter, R. Sadamoto, P. S. Sears, M. Wu, Acceptor specificity and inhibition of the bacterial cell-wall glycosyltransferase MurG, Chembiochem, vol. 4, 603-609, 2003
2003 T. K. Ritter, K. K. Mong, H. Liu, T. Nakatani, A programmable one-pot oligosaccharide synthesis for diversifying the sugar domains of natural products: a case study of vancomycin, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 42, 4657-4660, 2003
2003 L. V. Lee, M. L. Mitchell, S. J. Huang, V. V. Fokin, K. B. Sharpless, A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry, J Am Chem Soc, vol. 125, 9588-9589, 2003
2003 T. K. Mong, C. Y. Huang, A new reactivity-based one-pot synthesis of N-acetyllactosamine oligomers, J Org Chem, vol. 68, 2135-2142, 2003
2003 H. Liu, L. Wang, A. Brock, P. G. Schultz, A method for the generation of glycoprotein mimetics, J Am Chem Soc, vol. 125, 1702-1703, 2003
2003 H. C. Lin, W. B. Yang, Y. F. Gu, C. Y. Chen, C. Y. Wu, C. H. Lin, Stereoselective glycosylation of exo-glycals accelerated by Ferrier-type rearrangement, Org Lett, vol. 5, 1087-1089, 2003
2003 Cheng YJ, Chien YC, Hildesheim A, Hsu MM, Chen IH, Chuang J, Chang J, Ma YD, Luo CT, Hsu WL, Hsu HH, Huang H, Chang JF, Chen CJ, Yang CS., No Association Between Genetic Polymorphisms of CYP1A1, GSTM1, GSTT1, GSTP1, NAT2, and Nasopharyngeal Carcinoma in Taiwan, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, vol. 12(2), 179-180, 2003
2003 Chien YC, Chen CJ., Epidemiology and Etiology of Nasopharyngeal Carcinoma: Gene-Environment Interaction, CANCER REVIEWS: ASIA-PACIFIC, vol. 1(1), 1-19, 2003
2003 Cheng TJ, Tseng YF, Chang WM, Chang MD, Lai YK, Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2., Journal of cellular biochemistry, vol. 89(3), 589-602, 2003
2003 Wang LY, You SL, Lu SN, Ho HC, Wu MH, Sun CA, (Yang HI, Chien-Jen C, Risk of hepatocellular carcinoma and habits of alcohol drinking, betel quid chewing and cigarette smoking: a cohort of 2416 HBsAg-seropositive and 9421 HBsAg-seronegative male residents in Taiwan., CANCER CAUSES & CONTROL, vol. 14(3), 241-250, 2003
2003 Shen CN, Horb ME, Slack JM, Tosh D, Transdifferentiation of pancreas to liver., Mechanisms of development, vol. 120(1), 107-16, 2003
2003 C. N. Shen, J. R. Seckl, J. M. Slack, D. Tosh, Glucocorticoids suppress beta-cell development and induce hepatic metaplasia in embryonic pancreas, Biochemical journal, vol. 375, 41-50, 2003
2003 M. E. Horb, (C. N. Shen, D. Tosh, J. M. Slack, Experimental conversion of liver to pancreas, Current biology, vol. 13, 105-115, 2003
2003 Lu J, Chua HH, Chen SY, Chen JY, Tsai CH, Regulation of matrix metalloproteinase-1 by Epstein-Barr virus proteins, Cancer Res, vol. 63, 256-262, 2003
2003 Lo YC, (Lin SC, Shaw JF, Liaw YC*, Crystal structure of Escherichia coli thioesterase I/protease I/lysophospholipase L1: consensus sequence blocks constitute the catalytic center of SGNH-hydrolases through a conserved hydrogen bond network., Journal of molecular biology, vol. 330(3), 539-551, 2003
2003 K. I. Lin, C. Tunyaplin, K. Calame, Transcriptional regulatory cascades controlling plasma cell differentiation, Immunol Rev, vol. 194, 19-28, 2003
2003 K. L. Calame, K. I. Lin, C. Tunyaplin, Regulatory mechanisms that determine the development and function of plasma cells, Annu Rev Immunol, vol. 21, 205-230, 2003
2003 M. Shapiro-Shelef, K. I. Lin, L. J. McHeyzer-Williams, J. Liao, M. G. McHeyzer-Williams, K. Calame, Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells, Immunity, vol. 19, 607-620, 2003
2003 Lu, X.-A.; Chou, C.-H.; Wang, C.-C.; Hung, S.-C., Regioselective Esterification of Various D-Glucopyranosides: A Concise Synthesis of a Fully Protected Disaccharide Unit of Hyaluronic Acid, Synlett, vol. 9(S1), 1364-1366, 2003
2003 Tai, C.-A.; Kulkarni, S. S.; Hung, S.-C., Facile Cu(OTf)2-catalyzed Preparation of Per-O-acetylated Hexopyranoses with Stoichiometric Acetic Anhydride and Sequential One-pot Anomeric Substitution to Thioglycosides under Solvent-free Conditions, J. Org. Chem., vol. 68, 8719–8722, 2003
2003 Yang, W.-C.; Lu, X.-A.; Kulkarni, S. S.; Hung, S.-C., Cu(OTf)2-catalyzed Et3SiH-reductive Etherification of Various Carbonyl Compounds with Trimethylsilyl Ethers, Tetrahedron Lett., vol. 44, 7837–7840, 2003
2003 T. J. Chuang, W. C. Lin, H. C. Lee, C. W. Wang, K. L. Hsiao, Z. H. Wang, D. Shieh, S. C. Lin, L. Y. Ch'ang, A complexity reduction algorithm for analysis and annotation of large genomic sequences, Genome Res, vol. 13(2), 313-322 (impact factor: 14.397; ranking: 3/160: BIOTECHNOLOGY & APPLIED MICROBIOLOGY), 2003
2003 Yun-Ru Chen, A. Clay Clark*, Equilibrium and Kinetic Folding of the α-Helical Greek Key Protein Domain: Caspase Recruitment Domain (CARD) of RICK, Biochemistry, vol. 42, 6310-6320, 2003
2003 M. L. Lee*, C. J. Chen, I. J. Su, K. T. Chen, C. C. Yeh, C. C. King, H. L. Chang, Y. C. Wu, M. S. Ho, D. D. Jiang, W. F. Lin, H. C. Lang, T. Lin, M. H. Lai, J. T. Wang, C. H. Chen, Use of quarantine to prevent transmission of severe acute respiratory syndrome-Taiwan, MMWR Morb Mortal Wkly Rep, vol. 52, 680-683, 2003
2003 Y. L. Jeng, M. H. Wu, H. B. Huang, W. Y. Lin, S. L. You, T. Y. Chu, C. J. Chen, C. A. Sun*, The methylenetetrahydrofolate reductase 667C→T polymorphism and lung cancer risk in a Chinese population, Anticancer Res, vol. 23, 5149-5152, 2003
2003 S. Y. Tsai*, H. Y. Chiou, H. W. The, C. M. Chen, C. J. Chen, The effects of chronic arsenic exposure from drinking water on the neurobehavioral development in adolescence, Neurotoxicology, vol. 24, 747-753, 2003
2003 J. M. Lee*, Y. C. Lee, S. Y. Yang, S. P. Luh, C. J. Lee, C. J. Chen, M. T. Wu, The association of GSTT1 polymorphisms with the risk of esophageal cancer: Interactive with environmental exposure, J Genet Mol Biol, vol. 14, 41-50, 2003
2003 M. L. Lee*, C. J. Chen, I. J. Su, K. T. Chen, C. C. Yeh, C. C. King, H. L. Chang, Y. C. Wu, M. S. Ho, D. D. Jiang, D. Wong, Severe acute respiratory syndrome, Taiwan,2003, MMWR Morb Mortal Wkly Rep, vol. 52, 461-466, 2003
2003 M. W. Yu*, H. C. Chang, S. C. Chang, Y. F. Liaw, S. M. Lin, C. J. Liu, S. D. Lee, C. L. Lin, P. J. Chen, S. C. Lin, C. J. Chen, Role of reproductive factors in hepatocellular Carcinoma: Impact on hepatitis B- and C-related risk, Hepatology, vol. 38, 1393-1400, 2003
2003 R. M. Pfeiffer, A. Hildesheim, M. H. Gail, D. Pee, C. J. Chen, A. M. Goldstein*, S. R. Diehl, Robustness of inference on measured covariates to misspecification of genetic random effects in family studies, Genet Epidemiol, vol. 24, 14-23, 2003
2003 L. Y. Wang, S. L. You, S. N. Lu, H. C. Ho, M. H. Wu, C. A. Sun, H. I. Yang, C. J. Chen*, Risk of hepatocellular carcinoma and habits of alcohol drinking, betel quid chewing, and cigarette smoking: a cohort of 2416 HBsAg-seropositive and 9421 HBsAg-seronegative male residents in Taiwan, Cancer Cause Control, vol. 14, 241-250, 2003
2003 S. L. Wang*, J. M. Chiou, C. J. Chen, T. N. Wu, L. W. Chang, Prevalence of diabetes mellitus and its vascular complications in southwestern arseniasis-endemic and non-endemic areas in Taiwan, Environ Health Perspect, vol. 111, 155-159, 2003
2003 C. J. Chen*, Polyostotic Langerhans cell histiocytosis and El Nino: a Novel hypothesis (editorial), Acta Pediatr Taiwan, vol. 44, 4, 2003
2003 M. W. Yu*, S. Y. Yang, I. J. Pan, C. L. Lin, C. J. Liu, Y. F. Liaw, S. M. Lin, P. J. Chen, S. D. Lee, C. J. Chen, Polymorphisms in XRCC1 and glutathione S-transferase genes and hepatitis B-related hepatocellular carcinoma, J Natl Cancer Inst, vol. 95, 1485-1488, 2003
2003 Y. J. Cheng, Y. C. Chien, A. Hildesheim, M. M. Hsu, I. H. Chen, J. Chuang, J. Chang, C. T. Luo, Y. L. Ma, W. L. Hsu, H. X. Hsu, X. Huang, J. F. Chang, C. J. Chen*, C. S. Yang, No association between genetic polymorphisms of CYP1A1, GSTM1, GSTT1, GSTP1, and NAT2 and risk of nasopharyngeal carcinoma in Taiwan, Cancer Epidemiol Biomarkers Prev, vol. 12, 179-180, 2003
2003 E. Y. Cho, A. Hildesheim, C. J. Chen, M. M. Hsu, I. H. Chen, B. F. Mittl, P. H. Levine, M. Y. Liu, J. Y. Chen, L. A. Brinton, Y. J. Cheng*, C. S. Yang, Nasopharyngeal carcinoma and genetic polymorphisms of DNA repair enzymes XRCC1 and hOGG1, Cancer Epidemiol Biomarker Prev, vol. 12, 1100-1104, 2003
2003 C. H. Tseng*, C. K. Chong, C. P. Tseng, Y. M. Hsueh, H. Y. Chiou, C. C. Tseng, C. J. Chen, Long-term arsenic exposure and ischemic heart disease in arseniasis-hyperendemic villages in Taiwan, Toxicol Lett, vol. 137, 15-21, 2003
2003 M. S. Wu, C. Y. Wu, C. J. Chen, M. T. Lin, C. T. Shun, J. T. Lin*, Interleukin-10 genotypes associate with the risk of gastric carcinoma in Taiwanese Chinese, Int J Cancer, vol. 104, 617-623, 2003
2003 C. A. Sun*, D. M. Wu, C. C. Lin, S. N. Lu, S. L. You, L. Y. Wang, M. H. Wu, C. J. Chen, Incidence and co-factors of hepatitis C virus-related hepatocellular carcinoma: a prospective study of 12,008 men in Taiwan, Am J Epidemiol, vol. 157, 674-682, 2003
2003 Y. J. Zhang, Y. Chen, H. Ahsan, R. M. Lunn, P. H. Lee, C. J. Chen, R. M. Santella*, Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by Promoter hypermethylation and its relationship to aflatoxin B1-DNA adducts and p53 mutation in hepatocellular carcinoma, Int J Cancer, vol. 103, 440-444, 2003
2003 K. T. Chen*, C. J. Chen, E. W. Gregg, G. Imperatore, K. M. V. Narayan, Impaired fasting glucose and risk of diabetes in Taiwan: follow-up over three years, Diabetes Res Clin Pract, vol. 60, 177-182, 2003
2003 M. S. Wu, C. J. Chen, J. T. Lin*, Genetic alterations and polymorphisms in gastric cancer, J Formos Med Assoc, vol. 102, 447-458, 2003
2003 M. M. Wu, H. Y. Chiou, I. C. Ho, C. J. Chen, T. C. Lee*, Gene expression of inflammatory molecules in circulating lymphocytes from arsenic-exposed human subjects, Environ Health Perspect, vol. 111, 1429-1438, 2003
2003 C. J. Chen*, Y. C. Chien, Y. C. Chen, Evaluation of crisis management capability of public health and medical care system in Taiwan: review and perspective, Commun Develop J, vol. 104, 12-16, 2003
2003 Y. C. Chien, C. J. Chen*, Epidemiology and etiology of nasopharyngeal carcinoma: Gene-environment interaction, Cancer Rev Asia-Pacific, vol. 1, 1-19, 2003
2003 Y. M. Hsueh*, Y. F. Ko, Y. K. Huang, H. W. Chen, H. Y. Chiou, Y. L. Huang, M. H. Yang, C. J. Chen, Determination of inorganic arsenic methylation capability among residents of the Lanyang Basin, Taiwan: Arsenic and selenium exposure and alcohol consumption, Toxicol Lett, vol. 137, 49-63, 2003
2003 S. J. Twu*, T. J. Chen, C. J. Chen, S. J. Olsen, L. T. Lee, T. Fisk, K. H. Hsu, S. C. Chang, K. T. Chen, I. H. Chiang, Y. C. Wu, J. S. Wu, S. F. Dowell, Control measures for severe acute respiratory syndrome (SARS) in Taiwan, Emerg Infect Dis, vol. 9, 718-720, 2003
2003 Y. P. Liaw*, C. J. Chen, W. C. Lee, S. Y. Hsu, Construction and use of the digitized atlas of cancer mortality and incidence in Taiwan, Taiwan J Public Health, vol. 22, 227-236, 2003
2003 J. M. Lee*, Y. C. Lee, C. J. Chen, M. T. Wu, Application of genetic polymorphisms in DNA repair in the prediction of cancer susceptibility and clinical outcome, Current Pharmacogenomics, vol. 1, 175-186, 2003
2003 C. A. Sun*, C. J. Chen, Aflatoxin-induced hepatocarcinogenesis: Epidemiological evidence and mechanistic considerations, J Med Sci, vol. 23, 311-318, 2003
2003 S. S.-I Tseng-Rogenski, J.-L. Chong, C. B. Thomas, S. Enomoto, J. Berman, Functional conservation of Dhh1p, a DExD/H-box protein in Saccharomyces cerevisiae, Nucleic Acids Research, vol. 31, 4995-5002, 2003
2002 Y. Wang, Y. -C. Chang*, Grafting of Homo- Block Co-polypeptides on Solid Substrates by an Improved Surface-Initiated Vapor Deposition Polymerization, LANGMUIR, vol. 18, 9859-9866, 2002
2002 C.-S. Chen, S.-H. Wu, Synthesis of a Sialic Acid Dimer Derivative 2α-O-Benzyl Neu5Ac-α-(2-5) Neu5Gc, J. Org. Chem, vol. 67, 1376-1379, 2002
2002 P. T. Nyffeler, C. H. Liang, K. M. Koeller, The chemistry of amine-azide interconversion: catalytic diazotransfer and regioselective azide reduction, J Am Chem Soc, vol. 124, 10773-10778, 2002
2002 F. Fazio, M. C. Bryan, O. Blixt, J. C. Paulson, Synthesis of sugar arrays in microtiter plate, J Am Chem Soc, vol. 124, 14397-14402, 2002
2002 O. Plettenburg, V. Bodmer Narkevitch, Synthesis of alpha-galactosyl ceramide, a potent immunostimulatory agent, J Org Chem, vol. 67, 4559-4564, 2002
2002 M. L. Mitchell, F. Tian, L. V. Lee, Synthesis and evaluation of transition-state analogue inhibitors of alpha-1,3-fucosyltransferase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 3041-3044, 2002
2002 M. L. Mitchell, L. V. Lee, Synthesis and evaluation of six-membered GDP-iminocyclitol, Tetrahedron Lett, vol. 43, 5691-5693, 2002
2002 Y. Y. Wang, K. H. Khoo, S. T. Chen, C. C. Lin, C. H. Lin, Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 10, 1057-1062, 2002
2002 J. J. Liu, G. DeSantis, Structure-based rationalization of aldolase-catalyzed asymmetric synthesis, CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, vol. 80, 643-645, 2002
2002 T. Kanemitsu, O. Kanie, Solid-phase synthesis of oligosaccharides and on-resin quantitative monitoring using gated decoupling (13)C NMR, J Am Chem Soc, vol. 124, 3591-3599, 2002
2002 J. Liu, Selectfluor(TM)-mediated allylstannation of aldehydes and imines, Tetrahedron Lett, vol. 43, 3915-3917, 2002
2002 M. C. Bryan, O. Plettenburg, P. Sears, D. Rabuka, S. Wacowich Sgarbi, Saccharide display on microtiter plates, Chem Biol, vol. 9, 713-720, 2002
2002 Z. Zhang, Regioselective benzoylation of sugars mediated by excessive Bu2SnO: observation of temperature promoted migration, Tetrahedron, vol. 58, 6513-6519, 2002
2002 K. K. Mong, Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: a colon-rectal cancer antigen determinant, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 4087-4090, 2002
2002 O. Plettenburg, C. Mui, V. Bodmer Narkevitch, Rapid preparation of glycolipid libraries by cross metathesis, Adv Synth Catal, vol. 344, 622-626, 2002
2002 T. J. Tolbert, New methods for proteomic research: Preparation of proteins with N-terminal cysteines for labeling and conjugation, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 2171-2174, 2002
2002 Mannosyl transfer with regeneration of GDP-mannose, US Patent, vol. #6,485,930, 2002
2002 F. MorisVaras, Hydroxyazepanes as inhibitors of glycosidases and HIV protease, US Patent, vol. #6,462,193, 2002
2002 M. M. Thunnissen, B. Andersson, B. Samuelsson, J. Z. Haeggstrom, Crystal structures of leukotriene A4 hydrolase in complex with captopril and two competitive tight-binding inhibitors, Faseb J, vol. 16, 1648-1650, 2002
2002 A. R. Sawkar, W. C. Cheng, E. Beutler, W. E. Balch, J. W. Kelly, Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 99, 15428-15433, 2002
2002 R. Sadamoto, K. Niikura, P. S. Sears, H. Liu, A. Suksomcheep, F. Tomita, K. Monde, S. Nishimura, Cell-wall engineering of living bacteria, J Am Chem Soc, vol. 124, 9018-9019, 2002
2002 C. T. Guo, X. L. Sun, O. Kanie, K. F. Shortridge, T. Suzuki, D. Miyamoto, K. I. Hidari, Y. Suzuki, An O-glycoside of sialic acid derivative that inhibits both hemagglutinin and sialidase activities of influenza viruses, Glycobiology, vol. 12, 183-190, 2002
2002 J. Liu, C. Y. Huang, An efficient method for the preparation of 2-hydroxy- and 2-aminoglycals from glycosyl sulfoxides, Tetrahedron Lett, vol. 43, 3447-3448, 2002
2002 J. Liu, An efficient method for the cleavage of p-methoxybenzylidene (PMP), tetrahydropyranyl (THP) and 1,3-dithiane protecting groups by Selectfluor(TM), Tetrahedron Lett, vol. 43, 4037-4039, 2002
2002 J. J. Liu, Aldolase-catalyzed asymmetric synthesis of novel pyranose synthons as a new entry to heterocycles and epothilones, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 1404-1407, 2002
2002 Z. Y. Zhang, K. Niikura, X. F. Huang, A strategy for the one-pot synthesis of sialylated oligosaccharides, CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, vol. 80, 1051-1054, 2002
2002 A. Brik, Y. C. Lin, J. Elder, A quick diversity-oriented amide-forming reaction to optimize P-subsite residues of HIV protease inhibitors, Chem Biol, vol. 9, 891-896, 2002
2002 E. Chapman, S. Ding, P. G. Schultz, A potent and highly selective sulfotransferase inhibitor, J Am Chem Soc, vol. 124, 14524-14525, 2002
2002 E. Chapman, A pH sensitive colorometric assay for the high-throughput screening of enzyme inhibitors and substrates: a case study using kinases, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 10, 551-555, 2002
2002 I. Wang, S. H. Wu, H. K. Chang, R. C. Shieh, H. M. Yu, C. Chen, Solution Structure of a K-Channel Blocker from the Scorpion Tityus cambridgei, PROTEIN SCIENCE, vol. 11(2), 390-400, 2002
2002 W. B. Yang, S. S. Patil, C. H. Tsai, C. H. Lin, J.M. Fang, The synthesis of -gulose and -xylose from -gluconolactone, Tetrahedron, vol. 58, 253-259, 2002
2002 W. B. Yang, Y. Y. Yang, Y. F. Gu, S. H. Wang, C. C. Chang, C. H. Lin, Stereochemistry in the synthesis and reaction of exo-glycals, J Org Chem, vol. 67, 3773-3782, 2002
2002 C. F. Chang, W. B. Yang, C. C. Chang, C. H. Lin, Inter- and intramolecular alcohol additions to exo-glycals, Tetrahedron Lett, vol. 43, 6515-6519, 2002
2002 Cheng TJ, Rey PG, Poon T, Kan CC, Kinetic studies of human tyrosyl-DNA phosphodiesterase, an enzyme in the topoisomerase I DNA repair pathway., European journal of biochemistry / FEBS, vol. 269(15), 3697-3704, 2002
2002 Yang HI, Lu SN, Liaw YF, You SL, Sun CA, Wang LY, Hsiao CK, Chen PJ, Chen DS, Chen CJ, Hepatitis B e antigen and the risk of hepatocellular carcinoma., NEW ENGLAND JOURNAL OF MEDICINE, vol. 347(3), 168-174, 2002
2002 C. N. Shen, J.M.W. Slack, D. Tosh, Regulation of epithelia morphogenesis in hepatic transdifferentiation of pancreas, Differentiation, vol. 70, 363, 2002
2002 D. Tosh, (C. N. Shen, J. M. Slack, Differentiated properties of hepatocytes induced from pancreatic cells, Hepatology, vol. 36, 534-543, 2002