Key Achievements

Key Achievements

• 
  2025-06-11 Key Achievements

  Membrane Disruption Properties of Poly-Glycine Arginine Dipeptide Repeats Affected by Peptide Repeats Continuity and Membrane Composition

  Yun-Ru (Ruby) Chen
  Journal of Molecular Biology

• 
  2025-03-28 Key Achievements

  RRM1 O-GlcNAcylation inhibition suppresses pancreatic cancer via TK1-mediated replication stress.

  Chun-Mei Hu
  Cancer Gene Therapy

• 
  2025-02-28 Key Achievements

  Tau destabilization in a familial deletion mutant K280 accelerates its fibrillization and enhances the seeding effect

  Yun-Ru (Ruby) Chen
  Journal of Biological Chemistry

• 
  2025-02-05 Key Achievements

  Innovative cyclic peptide disrupts IL-17RB–MLK4 interaction for targeted pancreatic cancer therapy

  Chun-Mei Hu
  Biomedicine & Pharmacotherapy

• 
  2024-12-17 Key Achievements

  Tacrolimus regulates extracellular vesicle secretion from T cells via autophagy-lysosomal pathway

  Chun-Mei Hu
  Biomedicine & Pharmacotherapy

• 
  2024-10-30 Key Achievements

  Glycoengineering for a Universal COVID-19 Vaccine

  Chi-Huey Wong
  Scientia

• 
  2024-10-24 Key Achievements

  SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front

  Chun-Mei Hu
  Cancer Gene Therapy

• 
  2024-10-17 Key Achievements

  Reverse hierarchical DED assembly in the cFLIP-procaspase-8 and cFLIP-procaspase-8-FADD complexes

  Su-Chang Lin
  Nature Communications

• 
  2024-09-04 Key Achievements

  B4GALT1-dependent galectin-8 binding with TGF-β receptor suppresses colorectal cancer progression and metastasis

  Kuo-I Lin
  Cell Death & Disease

• 
  2024-06-25 Key Achievements

  Synthesis of a dendritic cell-targeted self-assembled polymeric nanoparticle for selective delivery of mRNA vaccines to elicit enhanced immune responses

  Chi-Huey Wong
  Chemical Science