具代表性研究發表

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年度 論文名稱
2019 Kong Y, Jia J, (Yang HI*, Lower Risk of Hepatocellular Carcinoma With Tenofovir vs Entecavir in Patients With Chronic Hepatitis B., JAMA oncology, vol. 5(6):915-916, 2019
2019 Liu J, Hu HH, Chang CL, Jen CL, Lee MH, Lu SN, Wang LY, Yuan Q, Xia NS, Sugiyama M, Nishida N, Mizokami M, Chen CJ, Chen PJ, (Yang HI*, Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection., Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 17(7):1413-1415, 2019
2019 Wang Chia-Chen, (Wang Yi-Sheng)*, Effective analysis of degree of polymerization of polysialic acids in mass spectrometry by combining novel sample preparation and dynamic instrument optimization methods, Carbohydrate Research, vol. 471, 78-84, 2019
2019 Shen CN, Goh KS, Huang CR, Chiang TC, Lee CY, Jeng YM, Peng SJ, Chien HJ, Chung MH, Chou YH, Hsieh CC, Kulkarni S, Pasricha PJ, Tien YW, Tang SC, Lymphatic vessel remodeling and invasion in pancreatic cancer progression., EBioMedicine, vol. 47, 98-113, 2019
2019 Lee, H.L., J.T.Tsai, C.Y. Chen, Y.C. Lin, C.B. Ho, L.L.Ting, C.C. Kuo, I.C. Lai, C.Y. Lin, J.H.Tang, Y.M. Huang, W.Y. Kao, S.W. Cheng, (C.N. Shen*, S.W.Chen*, J.F. Chiou*, Effectiveness of stereotactic ablative radiotherapy in patients with advanced hepatocellular carcinoma unsuitable for transarterial chemoembolization, Therapeutic Advances in Medical Oncology, vol. 11, 1758835919889002, 2019
2019 Chen X, Wong CH, (Ma C)*, Targeting the Bacterial Transglycosylase: Antibiotic Development from a Structural Perspective, ACS Infectious Diseases, vol. 5(9), 1493-1504, 2019
2019 Tseng YC, Wu CY, Liu ML, Chen TH, Chiang WL, Yu YH, Jan JT, Lin KI, Wong CH*, Ma C*, Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 116(10), 4200-4205, 2019
2019 Yang SC, Liu JJ, Wang CK, Lin YT, Tsai SY, Chen WJ, Huang WK, Tu PA, Lin YC, Chang CF, Cheng CL, Lin H, Lai CY, Lin CY, Lee YH, Chiu YC, Hsu CC, Hsu SC, Hsiao M, Schuyler SC, Lu FL*, (Lu J*), Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol. 33(9), 10577-10592, 2019
2019 Kuan II, Lee CC, Chen CH, (Lu J, Kuo YS, Wu HC, The extracellular domain of epithelial cell adhesion molecule (EpCAM) enhances multipotency of mesenchymal stem cells through EGFR-LIN28-LET7 signaling., The Journal of biological chemistry, vol. 294(19), 7769-7786, 2019
2019 This is for your information, For the information of my publications, please refer to PubMed and original publication websites. I am not responsible for any errors from any sources outside of original publication websites., Announcement, vol. 1-1, 2019
2019 Tseng, Y, -C., Wu, C.-Y., Liu, M.-L., Chen, T.-H., Chinag, W.-L., Yu, Y.-H., Jan, J.-T., (Lin, K.-I, Wong, C.-H., Ma, C., Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 116 (10) ,4200-4205, 2019
2019 Wang, Y.-H., Tsai, D.-Y., Ko, Y.-A., Yang, T.-T., Lin, I-Y., Hung, K.-H., Lin, K.-I)*, Blimp-1 contributes to the development and function of regulatory B cells, FRONTIERS IN IMMUNOLOGY, vol. 10:1909, 2019
2019 Tsai, D.-Y., Hung, K.-H., Chang, C.-W., Lin, K.-I)*, Regulatory Mechanisms of B cell responses and the implication in B cell-related diseases, JOURNAL OF BIOMEDICAL SCIENCE, vol. 26(1):64, 2019
2019 Liu, C.-H., Raj, S, Chen, C.-H., Hung, K.-H., Chou, C.-T., Chen, I.-Ho., Chien, J.-T., Lin, I-Y., Yang, S.-Y., Angata, T., Tsai, W.-C., Wei. J. C.-C., Tzeng, I-S., Hung, S.-C.*, Lin, K.-I)*, HLA-B27-mediated activation of TNAP phosphatase promotes pathogenic syndesmophyte formation in ankylosing spondylitis, JOURNAL OF CLINICAL INVESTIGATION, vol. 129 (12), 5357-5373, 2019
2019 C. M. Huang, S. Y. Lyu, K. H. Lin, C. L. Chen, M. H. Chen, H. W. Shih, N. H. Hsu, I. W. Lo, Y. L. Wang, Y. S. Li, C. J. Wu, T. L. Li*, Teicoplanin reprogrammed with the N-Acyl-glucosamine pharmacophore at the penultimate residue of aglycone acquires broad-spectrum antimicrobial activities effectively killing gram-positive and -negative pathogens, ACS INFECTIOUS DISEASES, vol. 5(3), 430-442, 2019
2019 H. W. Yeh, K. H. Lin, S. Y. Lyu, Y. S. Li, C. M. Huang, Y. L. Wang, H. W. Shih, N. S. Hsu, C. J. Wu, T. L. Li*, Biochemical and structural explorations for alpha-hydroxyacid oxidases reveal a 4-electron oxidative decarboxylation reaction, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 75(Pt 8), 733–742, 2019
2019 S. Y. Lyu, K. H. Lin, H. W. Yeh, Y. S. Li, C. M. Huang, Y. L. Wang, H. W. Shih, N. S. Hsu, C. J. Wu, T. L. Li*, The flavin mononucleotide cofactor in α-hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate oxidation level, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 75(10), 918-929, 2019
2019 Y. M. Liu, Y. L. Chan, T. H. Wu, T. L. Li, S. Hsia, Y. H. Chiu*, C. J. Wu*, Antitumor, inhibition of metastasis and radiosensitizing effects of total nutrition formula on Lewis tumor-bearing mice, NUTRIENTS, vol. 11(8), 1944, 2019
2019 T. H. Huang, T. H. Wu, Y. H. Guo, T. L. Li, Y. L. Chan, C. J. Wu*, The concurrent treatment of Scutellaria baicalensis Georgi enhances the therapeutic efficacy of cisplatin but also attenuates chemotherapy-induced cachexia and acute kidney injury, JOURNAL OF ETHNOPHARMACOLOGY, vol. 243, 112075, 2019
2019 T. H. Wu, K. Y. Yeh, C. H. Wang, H. Wang, T. L. Li, Y. L. Chan, C. J. Wu*, The combination of Astragalus membranaceus and Angelica sinensis inhibits lung cancer and cachexia through its immunomodulatory function, JOURNAL OF ONCOLOGY, vol. 2019, 9206951, 2019
2019 Lee CC*, Shih YC, Kang ML, Chang YC, Chuang LM, Devaraj R, (Juan LJ)*, Naa10p Inhibits Beige Adipocyte-Mediated Thermogenesis through N-alpha-acetylation of Pgc1alpha., Molecular Cell, vol. 76(3), 500-515.e8, 2019
2019 Fararjeh, A., Tu, S.H., Chen, L.C., Cheng, T.C., Liu, Y.R., Chang, H.L., Chang, H.W., Huang, C.C., Wang, H.C.R., (Hwang-Verslues, W.W., Wu, C.H., Ho, Y.S.*, Long-term exposure to extremely low-dose of nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induce non-malignant breast epithelial cell transformation through activation of the a9-nicotinic acetylcholine receptor-mediated signaling pathway, ENVIRONMENTAL TOXICOLOGY, vol. 34(1), 73-82, 2019
2019 Peng HY, Chang MC, Hu CM, Yang HI, Lee WH, Chang YT, Thrombospondin-2 is a Highly Specific Diagnostic Marker and is Associated with Prognosis in Pancreatic Cancer., Annals of Surgical Oncology, vol. 26(3),807-814, 2019
2019 Hu CM*, Tien SC, Hsieh PK, Jeng YM, Chang MC, Chang YT, Chen YJ, Chen YJ, Lee EY, Lee WH*, High glucose triggers nucleotide imbalance through O-GlcNAcylation of key enzymes and induces KRAS mutation in pancreatic cells, CELL METABOLISM, vol. 29, 1334-1349, 2019
2019 Hsieh YL, Tsai LK, Su FY, Tsai YC, Ko YL, Hu CM, Hsiu-Ming Shih, Lee WH*., NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase, CELL REPORTS, vol. 29, 2134-2143, 2019
2019 Kameyama, H.; Uchimura, K.; Yamashita, T.; Kuwabara, K.; Mizuguchi, M.; (Hung, S.-C.); Okuhira, K.; Masuda, T.; Kosugi, T.; Ohgita, T.; Saito, H.; Ando Y.; Nishitsuji, K.*, The Accumulation of Heparan Sulfate S-Domains in Kidney Transthyretin Deposits Accelerates Fibril Formation and Promotes Cytotoxicity, Am. J. Pathol, vol. 189, 308-319, 2019
2019 Yeh, C.-J.; Ku, C.-C.; Lin, W.-C.; Fan, C.-Y.; Medel Manuel L. Zulueta, M. M. L.; Manabe, Y.; Fukase, K.; Li, Y.-K.; (Hung, S.-C.*, Single-Step Per-O-Sulfonation of Sugar Oligomers with Concomitant 1,6-Anhydro Bridge Formation for Binding Fibroblast Growth Factors, CHEMBIOCHEM, vol. 20, 237-240, 2019
2019 Lin, Y.-C.; Ko, Y.-C.; (Hung, S.-C.); Lee, J.-H.; Lin, Y.-T.; Tsai, J.-Y.; Kung, P.-H.; Tsai, M.-C.; Chen, Y.-F.; Wu, C.-C.*, Selective Inhibition of PAR4-mediated Platelet Activation by a Synthetic Nonanticoagulant, Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 39, 694-703, 2019
2019 Sakamoto K, Ozaki T, Ko YC, Tsai CF, Gong Y, Morozumi M, Ishikawa Y, Uchimura K, Nadanaka S, Kitagawa H, Zulueta MML, Bandaru A, Tamura JI, (Hung SC, Kadomatsu K, Glycan sulfation patterns define autophagy flux at axon tip via PTPRsigma-cortactin axis., Nature Chemical Biology, vol. 15(7), 699-709, 2019
2019 Sianturi J, Manabe Y, Li HS, Chiu LT, Chang TC, Tokunaga K, Kabayama K, Tanemura M, Takamatsu S, Miyoshi E, (Hung SC, Fukase K, Development of α-Gal-Antibody Conjugates to Increase Immune Response by Recruiting Natural Antibodies., Angewandte Chemie (International ed. in English), vol. 58(14), 4526-4530, 2019