Chemical Biology Division 2020

Chen, Yun-Ru Ruby

  • Yao-Hsiang Shih§, Ling-Hsien Tu§, Ting-Yu Chang, Kiruthika Ganesan, Wei-Wei Chang, Pao-Sheng Chang, Yu-Sheng Fang, Yeh-Tung Lin, Lee-Way Jin, and Yun-Ru Chen*, 2020, “TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer’s disease”, NATURE COMMUNICATIONS, 11 (5950). (SCIE) (IF: 12.121; SCIE ranking: 8.5%)
  • Phillip Smethurst, Emmanuel Risse, Giulia E. Tyzack, Jamie S. Mitchell, Doaa M. Taha, Yun-Ru Chen, Jia Newcombe, John Collinge, Katie Sidle and Rickie Patani*, 2020, “Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis”, BRAIN, 143 (2):430-440. (SCIE) (IF: 11.337; SCIE ranking: 2.9%,4.8%)
  • Shih-Ling Huang, Lien-Szu Wu, Min Lee, Chin-Wen Chang, Wei-Cheng Cheng, Yu-Sheng Fang, Yun-Ru Chen, Pei-Lin Cheng, Che-Kun James Shen*, 2020, “A Robust TDP-43 Knock-In Mouse Model of ALS”, Acta Neuropathologica Communications, 8(1),3. (SCIE) (IF: 6.27; SCIE ranking: 10.3%)

Cheng, Wei-Chieh

  • Cheng Wei‐Chieh, You Ting‐Yun, Teo Zhen‐Zhuo, Sayyad Ashik A., Maharana Jitendra, Guo Chih‐Wei, Liang Pi‐Hui, Lin Chung‐Shun, Meng Fan‐Chun, 2020, “Further Insights on Structural Modifications of Muramyl Dipeptides to Study the Human NOD2 Stimulating Activity”, Chemistry – An Asian Journal, 15(22) 3836-3844.
  • Cheng WC, Liu WJ, Hu KH, Tan YL, Lin YT, Chen WA, Lo LC, 2020, “Rapid Synthesis of a Natural Product-Inspired Uridine Containing Library.”, ACS combinatorial science, 22(11), 600-607. (SCIE) (IF: 4.605; SCIE ranking: 9%; SCIE ranking: 23.9%,34.4%,37.3%; SCIE ranking: 32.7%,6.7%,26.1%)

Li, Tsung-Lin

  • Y. M Liu, T. H. Wu, Y. H. Chiu, H. Wang, T. L. Li, S. Hsia, Y. L. Chan*, C. J. Wu*, 2020, “Positive effects of preventive nutrition supplement on anticancer radiotherapy in lung cancer bearing mice”, CANCERS, 12(9), 2445. (SCIE) (IF: 6.126; SCIE ranking: 46.2%,84.8%)
  • S. Malek Zadeh, E. Astani, Z. C. Wang, K. Adhikari, R. Rattinam, T. L. Li*, 2020, “Theoretical study of intermolecular interactions between critical residues of membrane protein MraYAA and Promising Antibiotic Muraymycin D2”, ACS OMEGA, 5(36), 22739–22749. (SCIE) (IF: 2.87; SCIE ranking: 45.8%)
  • K. Adhikari, I. W. Lo, C. L. Chen, Y. L. Wang, K. H. Lin, S. MalekZadeh, R. Rattinam, Y. S. Li, C. J. Wu, T. L. Li*, 2020, “Chemoenzymatic synthesis and biological evaluation for bioactive molecules derived from bacterial benzoyl coenzyme A ligase and plant type III polyketide synthase”, BIOMOLECULES, 10(5), 738. (SCIE) (IF: 4.082; SCIE ranking: 46.2%,84.8%)
  • K. H. Lin, S. Y. Lyu, H. W. Yeh, Y. S. Li, N. S. Hsu, C. M. Huang, Y. L. Wang, H. W. Shih, Z. C. Wang, C. J. Wu, T. L. Li*, 2020, “Structural and chemical trapping of short-lived flavin-oxide intermediates reveals substrate-directed reaction multiplicity”, PROTEIN SCIENCE, 29, 1655-1666. (SCIE) (IF: 3.876; SCIE ranking: 35.4%)

Ma, Che Alex

  • Liu YM, Shahed-Al-Mahmud M, Chen X, Chen TH, Liao KS, Lo JM, Wu YM, Ho MC, Wu CY, Wong CH, Jan JT, Ma C*, 2020, “A carbohydrate-binding protein from the edible Lablab beans effectively blocks the infections of influenza viruses and SARS-CoV-2”, Cell Reports, 108016. (SCIE) (IF: 8.109; SCIE ranking: 15.4%)
  • Zhou D, Duyvesteyn HME, Chen CP, Huang CG, Chen TH, Shih SR, Lin YC, Cheng CY, Cheng SH, Huang YC, Lin TY, Ma C, Huo J, Carrique L, Malinauskas T, Ruza RR, Shah PNM, Tan TK, Rijal P, Donat RF, Godwin K, Buttigieg KR, Tree JA, Radecke J, Paterson NG, Supasa P, Mongkolsapaya J, Screaton GR, Carroll MW, Gilbert-Jaramillo J, Knight ML, James W, Owens RJ, Naismith JH, Townsend AR, Fry EE, Zhao Y, Ren J, Stuart DI, Huang KYA, 2020, “Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient”, Nature Structural & Molecular Biology, 25. (SCIE) (IF: 11.98; SCIE ranking: 4.7%,2.8%,7.7%)
  • Huang CF, Chang WH, Lee TK, Joti Y, Nishino Y, Kimura T, Suzuki A, Bessho Y, Lee TT, Chen MC, Yang SM, Hwu Y, Huang SH, Li PN, Chen P, Tseng YC, Ma C, Hsu TL, Wong CH, Tono K, Ishikawa T, Liang KS, 2020, “XFEL coherent diffraction imaging for weakly scattering particles using heterodyne interference”, AIP Advances, 10(5) 055219. (SCIE) (IF: 1.337; SCIE ranking: 46.2%,84.8%)
  • Chen JR, Liu YM, Tseng YC, Ma C*, 2020, “Better influenza vaccines: an industry perspective”, Journal of Biomedical Science, 27(1). (SCIE) (IF: 5.762; SCIE ranking: 24.1%,12.2%)

Wong, Chi-Huey

  • Y.-M. Liu, M. Shahed-Al-Mahmud, X. Chen, T.-H. Chen, K.-S. Liao, J. M. Lo, Y.-M Wu., M.-C. Ho, C.-Y. Wu, C.-H. Wong, J.-T. Jan, C. Ma, 2020, “A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2”, Cell Reports, 32(6) 108016. (SCIE) (IF: 8.109; SCIE ranking: 15.4%)
  • H.-Y. Liao, S.-C. Wang, Y.-A. Koa, K.-I. Lin, C. Ma, T.-J. R. Cheng, and C.-H. Wong, 2020, “Chimeric hemagglutinin vaccine elicits broadly protective CD4 and CD8 T cell responses against multiple influenza strains and subtypes”, Proceedings of the National Academy of Sciences, 117(30) 17757-17763.
  • Y.-H. Chang, J.-C. Wu, H.-M. Yu, H.-T. Hsu, Y.-T. Wu, A. L.-T. Yu, C.-D. T. Yu and C.-H. Wong, 2020, “Design and synthesis of glyco-peptides as anti-cancer agents targeting thrombin-protease activated receptor-1 interaction”, Chemical Communications, 56(43) 5827-5830. (SCIE) (IF: 5.996; SCIE ranking: 19.2%)
  • J. Woodring, S.-H. Lu, L. Krasnova, S.-C. Wang, J.-B. Chen, C.-C. Chou, Y.-C. Huang, T.-J. Cheng, Y.-T. Wu, Y.-H. Chen, J.-M. Fang, M.-D. Tsai, C.-H. Wong, 2020, “Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein”, Journal of Medicinal Chemistry, 63(1), 205-215. (SCIE) (IF: 6.205; SCIE ranking: 4.9%)
  • W.-F. Wang, M.-Y. Jade Lu, T.-J. R. Cheng, Y.-C. Tang, Y.-C. Teng, T.-Y. Hwa, Y.-H. Chen, M.-Y. Li, M.-H. Wu, P.-C. Chuang, R. Jou, C.-H. Wong, and W.-H. Li, 2020, “Genomic Analysis of Mycobacterium tuberculosis Isolates and Construction of a Beijing Lineage Reference Genome”, Genome Biology and Evolution, 12(2) 3890-3905. (SCIE) (IF: 3.462; SCIE ranking: 35.3%,34.8%)
  • C.-Y. Wu, H.-Y. Chuang, C.-H. Wong, 2020, “Influenza virus neuraminidase regulates host CD8(+) T-cell response in mice.”, Communications biology, 3(1), 748. (SCIE) (IF: 9.601; SCIE ranking: 46.2%,84.8%; SCIE ranking: 14%,8.6%,10.7%; SCIE ranking: 8.1%,3.2%,12.3%)
  • E. A. Wang, W.-Y. Chen, C.-H. Wong, 2020, “Multiple Growth Factor Targeting by Engineered Insulin-like Growth Factor Binding Protein-3 Augments EGF Receptor Tyrosine Kinase Inhibitor Efficacy”, Scientific Reports, 10(1). (SCIE) (IF: 3.998; SCIE ranking: 23.9%)
  • S. Dey, H.-J. Lo, C.-H. Wong,, 2020, “Programmable One-Pot Synthesis of Heparin Pentasaccharide Fondaparinux”, Organic Letters, 22(12) 4638-4642. (SCIE) (IF: 6.091; SCIE ranking: 7%)
  • C.-W. Cheng, C.-Y. Wu, W.-L. Hsu, C.-H. Wong, 2020, “Programmable One-Pot Synthesis of Oligosaccharides”, Biochemistry, 59(34) 3078-3088. (SCIE) (IF: 2.865; SCIE ranking: 56.9%)
  • C.-Y. Lin, H.-Y. Wu, P.-S. Wu, Y.-L. Hsu, T.-J. Cheng, J.-H. Liu, R.-J. Huang, T. H. Hsiao, C.-J. Wang, P.-F. Hung, A. Lan, Y.-J. Chen, S.-H. Pan, R.-J. Chein, C.-H. Wong, P.-C. Yang, 2020, “Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein”, Journal of Medicinal Chemistry, 63(6) 3172-3187. (SCIE) (IF: 6.205; SCIE ranking: 4.9%)
  • S. Pawar, L. Hsu, T. N. Reddy, M. Ravinder, C.-T. Ren, Y.-W. Lin, Y.-Y. Cheng, T.-W. Lin, T.-L. Hsu, S.-K. Wang, C.-H. Wong, C.-Y. Wu, 2020, “Synthesis of Asymmetric N-Glycans as Common Core Substrates for Structural Diversification through Selective Enzymatic Glycosylation”, ACS Chemical Biology, 15(9) 2382-2394. (SCIE) (IF: 4.434; SCIE ranking: 26.6%)
  • S. Shivatare, C.-H. Wong, 2020, “Synthetic Carbohydrate Chemistry and Translational Medicine.”, The Journal of organic chemistry, 85(24), 15780-15800. (SCIE) (IF: 2.304; SCIE ranking: 15.8%; SCIE ranking: 45.6%,44.4%)
  • L.-T. Chiu, N. Sabbavarapu, W.-C. Lin, C.-Y. Fang, C.-C. Wu, T.-J. Cheng, C.-H. Wong, S.-C. Hung, 2020, “Trisaccharide Sulfate and Its Sulfonamide as an Effective Substrate and Inhibitor of Human Endo-O-sulfatase-1”, Journal of the American Chemical Society, 142(11) 5282-5292. (SCIE) (IF: 14.612; SCIE ranking: 7.3%)
  • C.-F. Huang, W.-H. Chang, T.-K. Lee, Y. Joti, Y. Nishino, T. Kimura, A. Suzuki, Y. Bessho,T.-T. Lee, M.-C. Chen, S.-M. Yang, Y. Hwu, S.-H. Huang, P.-N. Lee, P. Chen, Y.-C. Tseng, C. Ma, T.-L. Hsu, C.-H. Wong, K. Tono, T. Ishikawa, and K. Liang, 2020, “XFEL coherent diffraction imaging for weakly scattering particles using heterodyne interference”, AIP Advances, 10(5) 055219. (SCIE) (IF: 1.337; SCIE ranking: 46.2%,84.8%)

Wu, Chung-Yi

  • Chein-Hung Chen, Ya-Ping Lin, Chien-Tai Ren, Sachin S Shivatare , Nan-Hon Lin, Chung-Yi Wu , Chung-Hsuan Chen, Jung-Lee Lin*, 2020, “Enhancement of fucosylated N-glycan isomer separation with an ultrahigh column temperature in porous graphitic carbon liquid chromatography-mass spectrometry”, JOURNAL OF CHROMATOGRAPHY A, 1632, 461610. (SCIE) (IF: 4.049; SCIE ranking: 16.9%,16.3%)
  • Mettu Ravinder, Kuo-Shiang Liao, Yang-Yu Cheng, Sujeet Pawar, Tzu-Lung Lin, Jin-Town Wang, and Chung-Yi Wu*, 2020, “A Synthetic Carbohydrate–Protein Conjugate Vaccine Candidate against Klebsiella pneumoniae Serotype K2”, JOURNAL OF ORGANIC CHEMISTRY, online. (SCIE) (IF: 4.335; SCIE ranking: 15.8%)
  • Cheng-Wei Cheng , Chung-Yi Wu, Wen-Lian Hsu , Chi-Huey Wong*, 2020, “Programmable One-Pot Synthesis of Oligosaccharides”, BIOCHEMISTRY, 59(34),3078-3088. (SCIE) (IF: 2.865; SCIE ranking: 56.9%)
  • Yo-Min Liu, Md. Shahed-Al-Mahmud, Xiaorui Chen, Ting-Hua Chen, Kuo-Shiang Liao, Jennifer M. Lo, Yi-Min Wu, Meng-Chiao Ho, Chung-Yi Wu, Chi-Huey Wong, Jia-Tsrong Jan, and Che Ma*, 2020, “A carbohydrate-binding protein from the edible Lablab beans effectively blocks the infections of influenza viruses and SARS-CoV-2”, CELL REPORTS, 32(6), 118016. (SCIE) (IF: 8.109; SCIE ranking: 15.4%)
  • Sujeet Pawar, Li Hsu, Thatikonda Narendar Reddy, Mettu Ravinder, Chien-Tai Ren, Yu-Wei Lin, Yang-Yu Cheng, Tzu-Wen Lin, Tsui-Ling Hsu, Sheng-Kai Wang, Chi-Huey Wong*, and Chung-Yi Wu*, 2020, “Synthesis of Asymmetric N-Glycans as Common Core Substrates for Structural Diversification through Selective Enzymatic Glycosylation”, ACS CHEMICAL BIOLOGY, 15(9), 2382-2394. (SCIE) (IF: 4.434; SCIE ranking: 26.6%)
  • Ravinder Mettu, Chiang-Yun Chen and Chung-Yi Wu*, 2020, “Synthetic carbohydrate-based vaccines: challenges and opportunities”, JOURNAL OF BIOMEDICAL SCIENCE, 27(9). (SCIE) (IF: 5.762; SCIE ranking: 24.1%,12.2%)