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Single Site N‑Glycosylation of B Cell Maturation Antigen (BCMA) Inhibits γ‑Secretase-Mediated Shedding and Improves Surface Retention and Cell Survival

Single Site N‑Glycosylation of B Cell Maturation Antigen (BCMA) Inhibits γ‑Secretase-Mediated Shedding and Improves Surface Retention and Cell Survival

翁啟惠
ACS Chemical Biology
December 12, 2023

Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA)

Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA)

翁啟惠
Proceedings of the National Academy of Sciences
November 27, 2023

Oncogenic KRAS, Mucin 4, and Activin A-Mediated Fibroblast Activation Cooperate for PanIN Initiation

Oncogenic KRAS, Mucin 4, and Activin A-Mediated Fibroblast Activation Cooperate for PanIN Initiation

胡春美, 李文華
Advanced Science
November 14, 2023

Core clock gene BMAL1 and RNA-binding protein MEX3A collaboratively regulate Lgr5 expression in intestinal crypt cells

Core clock gene BMAL1 and RNA-binding protein MEX3A collaboratively regulate Lgr5 expression in intestinal crypt cells

黃雯華
Scientific Reports
October 16, 2023

Quantitative mass spectrometric analysis of hepatocellular carcinoma biomarker alpha-fetoprotein

Quantitative mass spectrometric analysis of hepatocellular carcinoma biomarker alpha-fetoprotein

翁啟惠
RSC Chemical Biology
October 09, 2023

Detecting intragenic trans-splicing events from non-co-linearly spliced junctions by hybrid sequencing

Detecting intragenic trans-splicing events from non-co-linearly spliced junctions by hybrid sequencing

莊樹諄
Nucleic Acids Research
July 27, 2023

Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity

Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity

陳韻如
communications biology
July 21, 2023

Effective Organotin-Mediated Regioselective Functionalization of Unprotected Carbohydrates

Effective Organotin-Mediated Regioselective Functionalization of Unprotected Carbohydrates

翁啟惠
The Journal of Organic Chemistry
June 02, 2023

Inhibition of SARS-CoV-2-mediated thromboinflammation by CLEC2.Fc

Inhibition of SARS-CoV-2-mediated thromboinflammation by CLEC2.Fc

謝世良
EMBO Molecular Medicine
May 22, 2023

N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry

N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry

李宗璘
Nature Communications
May 03, 2023

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