化學生物學研究領域 2023

Chen, Yun-Ru Ruby

  • Tien-Ying Tsai§, Chun-Yu Chen§, Tien-Wei Lin, Tien-Chang Lin, Feng-Lan Chiu, Orion Shih, Ming-Yun Chang, Yu-Chun Lin, An-Chung Su, U-Ser Jeng, Hung-Chih Kuo, Chi-Fon Chang, and Yun-Ru Chen*, 2023, “Amyloid Modifier SERF1a Interacts with PolyQ-expanded Huntingtin Exon 1 via Helical Interactions and Exacerbates PolyQ-induced Toxicity”, Communications Biology, 6, 767. (SCIE)
  • Tien-Wei Lin, Jung-Kai Chang, Yih-Ru Wu, Tsung-Hsien Sun, Yang-Yu Cheng, Chien-Tai Ren, Mei-Hung Pan, Jin-Lin Wu, Kuo-Hsuan Chang, Hwai-I Yang, Chiung-Mei Chen*, Chung-Yi Wu*, and Yun-Ru Chen*, 2023, “Ganglioside-focused Glycan Array Reveals Abnormal Anti-GD1b Auto-antibody in Plasma of Preclinical Huntington’s Disease”, MOLECULAR NEUROBIOLOGY, 60(7), 3873-3882. (SCIE)

Cheng, Wei-Chieh

  • Lin Hung-Yi, Chang Shih-Ying, Teng Hsuan-Hsuan, Wu Hsi-Ju, Li Huang-Yi, Cheng Chia-Chun, Chuang Chih-Kuang, Lin Hsiang-Yu, Lin Shuan-Pei, Cheng Wei-Chieh, 2023, “Discovery of small-molecule protein stabilizers toward exogenous alpha-l-iduronidase to reduce the accumulated heparan sulfate in mucopolysaccharidosis type I cells”, European Journal of Medicinal Chemistry, 247, 115005. (SCIE)
  • Li Huang-Yi, Lee Ni-Chung, Chiu Yu-Ting, Chang Yu-Wen, Lin Chu-Chung, Chou Cheng-Li, Chien Yin-Hsiu, Hwu Wuh-Liang, Cheng Wei-Chieh, 2023, “Harnessing polyhydroxylated pyrrolidines as a stabilizer of acid alpha-glucosidase (GAA) to enhance the efficacy of enzyme replacement therapy in Pompe disease”, BIOORGANIC & MEDICINAL CHEMISTRY, 78, 117129. (SCIE)

Hung, Shang-Cheng

  • Nguan HS, Tsai ST, Liew CY, Reddy NS, Hung SC, Ni CK*, 2023, “The collision-induced dissociation mechanism of sodiated Hex-HexNAc disaccharides.”, Physical chemistry chemical physics : PCCP, 25(33), 22179-22194. (SCIE)

Li, Tsung-Lin

  • S. H. Liu, H. T. Huang, I. W. Lo, Y. C. Lin, G. Y. Liao, C. H. Chao, H. C. Huang, F. R. Chang, T. L. Li, Y. C. Shen, C. C. Liao*, 2023, “Potential natural product 3,4-seco-schitriterpenoids from Kadsura japonica L. as anti-neuroinflammatory agents”, BIOORGANIC CHEMISTRY, 141, 106843. (SCIE)
  • S. S. Chang, H. T. Huang, W. C. Wei, I. W. Lo, Y. C. Lin, C. H. Chao, G. Y. Liao, Y. C. Shen, J. J. Chen, T. L. Li, L. T. Lin, C. J. Tai, Y. H. Kuo, C. C. Liaw*, 2023, “Anti-inflammatory Effect of Euphane-and Tirucallane-type Triterpenes Isolated from Traditional Herb Euphorbia neriifolia L”, FRONTIERS IN CHEMISTRY, 11, 1-13, 10.3389/fchem.2023.1. (SCIE)
  • Y. L. Wang, C. Y. Chang, N. S. Hsu, I. W. Lo, K. H. Lin, C. L. Chen, C. F. Chang, Z. C. Wang, Y. Ogasawara, T. Dairi, C. Maruyama, Y. Hamano*, T. L. Li*, 2023, “N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry”, NATURE COMMUNICATIONS, 14:2528 (, 1-14. (SCIE)
  • H. T. Huang, I. W. Lo, Y. C. Lin, G. Y. Liao, Y. S. Lin, L. J. Zhang, T. L. Li, C. Ching Liaw*, Y. H. Kuo*, 2023, “Kaguacidine A: a novel spirohydantoin-containing cucurbitane glycoside from vines of Momordica charantia”, NATURAL PRODUCT RESEARCH, DOI:10.1080/14786419.202, 1-8. (SCIE)

Ma, Che Alex

  • Wu CY, Kao SE, Tseng YC, Lin YP, Hou JT, Wu LY, Chiu S, Ma CA, Hsiao PW, Hsiao J, Chen JR, 2023, “Pilot-scale production of inactivated monoglycosylated split H(1)N(1) influenza virus vaccine provides cross-strain protection against influenza viruses.”, Antiviral research, 216, 105640. (SCIE)
  • Huang KA*, Chen X, Mohapatra A, Nguyen HTV, Schimanski L, Tan TK, Rijal P, Vester SK, Hills RA, Howarth M, Keeffe JR, Cohen AA, Kakutani LM, Wu YM, Shahed-Al-Mahmud M, Chou YC, Bjorkman PJ, Townsend AR, Ma C*, 2023, “Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2.”, Nature communications, 14(1), 311. (SCIE)
  • Nguyen HTV, Chen X, Parada C, Luo AC, Shih O, Jeng US, Huang CY, Shih YL*, Ma C*, 2023, “Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome”, Nature Communications, 14(1), 1903. (SCIE)

Wong, Chi-Huey

  • C.-C. Chen, H.-W. Huang, B.-R. Chen, and C.-H. Wong, 2023, “Quantitative Mass Spectrometric Analysis of Hepatocellular Carcinoma Biomarker Alpha-Fetoprotein”, RSC Chemical Biology, published online ahead of print, published online ahead of print. (SCIE)
  • Z.-R. Li, R. Li, L. Pasternack, P. Chen, C.-H. Wong, 2023, “Chemical Synthesis of a Keto Sugar Nucleotide”, The Journal of Organic Chemistry, 88(11), 7580-7585. (SCIE)
  • Y. Zhou, K.-S. Liao, T.-Y. Chen, Y. SY Hsieh, C.-H. Wong, 2023, “Effective Organotin-Mediated Regioselective Functionalization of Unprotected Carbohydrates.”, The Journal of organic chemistry, 88(11), 7141-7151. (SCIE)
  • O. Chou, Y.-P. Juang, T.-L. Chao, S.-F. Tsai, P.-F. Chiu, C.-T. Chiou, K.-C. Tsai, S.-Y. Chang, P.-H. Liang, C.-H. Wong, 2023, “Isolation of Anti-SARS-CoV-2 Natural Products Extracted from Mentha canadensis and the Semi-synthesis of Antiviral Derivatives”, Journal of natural products, 86(6), 1428-1436. (SCIE)
  • C.-W. Cheng, C.-Y. Wu, S.-W. Wang, J.-Y. Chen, C.-C. Kung, K.-S. Liao, C.-H. Wong, 2023, “Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA).”, Proceedings of the National Academy of Sciences of the United States of America, 120(49), e2314392120. (SCIE)
  • S.-W. Wang, Y.-A. Ko, C.-Y. Chen, K.-S. Liao, Y.-H. Chang, H.-Y. Lee, Y.-H. Yu, Y.-H. Lih, Y.-Y. Cheng, H.-H. Lin , T.-L. Hsu, C.-Y. Wu, K.-I. Lin, C.-H. Wong, 2023, “Mechanism of Antigen Presentation and Specificity of Antibody Cross-Reactivity Elicited by an Oligosaccharide-Conjugate Cancer Vaccine.”, Journal of the American Chemical Society, 145(17), 9840-9849. (SCIE)
  • V. S Shivatare, H.-W. Huang, T.-H. Tseng, P.-K. Chuang, Y.-F. Zeng, C.-H. Wong, 2023, “Probing the Internalization and Efficacy of Antibody‐Drug Conjugate via Site‐Specific Fc‐Glycan Labelling of a Homogeneous Antibody Targeting SSEA‐4 Bearing Tumors”, Israel Journal of Chemistry, Online, ahead of print. (SCIE)
  • H.-W. Huang, C.-C. Chen, K.-I. Lin, T.-L. Hsu, C.-H. Wong, 2023, “Single Site N-Glycosylation of B Cell Maturation Antigen (BCMA) Inhibits gamma-Secretase-Mediated Shedding and Improves Surface Retention and Cell Survival.”, ACS chemical biology, epub, ahead of print. (SCIE)
  • V.-S. Shivatare , P.-K. Chuang , T.-H. Tseng , Y.-F. Zeng , H.-W. Huang , G. Veeranjaneyulu , H.-C. Wu , C.-H. Wong*, 2023, “Study on antibody Fc-glycosylation for optimal effector functions.”, Chemical communications (Cambridge, England), 59, 5555-5558.