醫學生物學研究領域 2019

Hsiao, Michael

  • Pai S, Bamodu OA, Lin YK, Lin CS, Chu PY, Chien MH, Wang LS, Hsiao M, Yeh CT, Tsai JT., 2019, “D47-SIRPα signaling induces epithelial-mesenchymal transition, cancer stemness and links to a poor prognosis in patients with oral squamous cell carcinoma”, Cells, 8(12). (SCIE)
  • Chiou J, Chang YC, Tsai HF, Lin YF, Huang MS, Yang CJ, Hsiao M*, 2019, “Follistatin-like protein 1 inhibits lung cancer metastasis by preventing proteolytic activation of osteopontin”, Cancer Research, 79(24),6113-6125. (SCIE)
  • Li CH, Chang YC, Hsiao M*, Liang SM, 2019, “FOXD1 and Gal-3 form a positive regulatory loop to regulate lung cancer aggressiveness”, Cancers, 11(12). (SCIE)
  • Wen YT, Wu ATH, Bamodu OA, Wei L, Lin CM, Yen Y, Chao TY, Mukhopadhyay D, Hsiao M*, Huang HS, 2019, “A novel multi-target small molecule, LCC-09, inhibits stemness and therapy-resistant phenotypes of glioblastoma cells by increasing miR-34a and deregulating the DRD4/Akt/mTOR signaling axis”, Cancers, 11(10) 1442. (SCIE)
  • Chiou J, Chang YC, Jan YH, Tsai HF, Yang CJ, Huang MS, Yu YL, Hsiao M*, 2019, “Overexpression of BZW1 is an independent poor prognosis marker and its down-regulation suppresses lung adenocarcinoma metastasis”, Scientific Reports, 9(1), 14624. (SCIE)
  • Yang SC, Liu JJ, Wang CK, Lin YT, Tsai SY, Chen WJ, Huang WK, Tu PA, Lin YC, Chang CF, Cheng CL, Lin H, Lai CY, Lin CY, Lee YH, Chiu YC, Hsu CC, Hsu SC, Hsiao M, Schuyler SC, Lu FL, Lu J, 2019, “Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2.”, FASEB Journal, 33(9):10577-10592. (SCIE)
  • Chang YC, Tsai HF, Huang SP, Chen CL, Hsiao M*, Tsai WC, 2019, “Enrichment of aldolase C correlates with low non-mutated IDH1 expression and predicts a favorable prognosis in glioblastomas”, Cancers, 11(9). pii: E1238. (SCIE)
  • CH Lin, HY Li, YP Liu, PF Kuo, WC Wang, FC Lin, WL Chang, BS Sheu, YC Wang, WC Hung, HC Cheng, YC Yao, MJ Calkins., M Hsiao, PJ Lu, 2019, “High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma”, Therapeutic Advances in Medical Oncology, 11 175883591987532. (SCIE)
  • Tai PA, Liu YL, Wen YT, Lin CM, Huynh TT, Hsiao M, Wu ATH, Wei L, 2019, “The development and applications of a dual optical imaging system for studying glioma stem cells”, Molecular Imaging, 18:1536012119870899. (SCIE)
  • Chang YC, Chiou J, Yang YF, Su CY, Lin YF, Yang CN, Lu PJ, Huang MS, Yang CJ, Hsiao M*, 2019, “Therapeutic targeting of aldolase A interactions inhibits lung cancer metastasis and prolongs survival”, Cancer Research, 79(18),4754-4766. (SCIE)
  • Jan YH, Lai TC, Yang CJ, Huang MS, Hsiao M*, 2019, “A co-expressed gene status of adenylate kinase 1/4 reveals prognostic gene signature associated with prognosis and sensitivity to EGFR targeted therapy in lung adenocarcinoma”, Scientific Reports, 9(1), 12329. (SCIE)
  • Chang CY, Chang SL, Leu JD, Chang YC, Hsiao M, Lin LT, Lin HN, Lee YJ, 2019, “Comparison of cofilin1 and Twist1 protein expression in human nonsmall cell lung cancer tissues.”, Oncology Reports, 42(2),805-816. (SCIE)
  • Chan MH, Liu RS, Hsiao M*, 2019, “Graphitic carbon nitride-based nanocomposites and their biological applications: a review.”, Nanoscale, 11(32),14993-15003, Cite 2. (SCIE)
  • Su YK, Bamodu OA, Tzeng YM, Hsiao M, Lin CM, Yeh CT, 2019, “Ovatodiolide inhibits the oncogenicity and cancer stem cell-like phenotype of the glioblastoma cells, as well as potentiate the anticancer effect of temozolomide”, Phytomedicine, 61. (SCIE)
  • Tien CP, Chen CH, Lin WY, Liu CS, Liu KJ, Hsiao M, Chang YC, Hung SC, 2019, “Ambient particulate matter attenuates Sirtuin1 and augments SREBP1-PIR axis to induce human pulmonary fibroblast inflammation: molecular mechanism of microenvironment associated with COPD.”, Aging (Albany, NY), 11(13),4654-4671.
  • Huang YJ, Jan YH, Chang YC, Tsai HF, Wu ATH, Chen CL, Hsiao M*, 2019, “ATP Synthase Subunit Epsilon Overexpression Promotes Metastasis by Modulating AMPK Signaling to Induce Epithelial-to-Mesenchymal Transition and Is a Poor Prognostic Marker in Colorectal Cancer Patients”, Journal of Clinical Medicine, 8(7), 1070. (SCIE)
  • Hung WY, Chang JH, Cheng Y, Cheng GZ, Huang HC, Hsiao M, Chung CL, Lee WJ, Chien MH, 2019, “Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response”, Cell Death Disease, 10(8):538. (SCIE)
  • Chan MH, Lai CY, Chan YC, Hsiao M*, Chung RJ, Chen X, Liu RS, 2019, “Development of upconversion nanoparticle-conjugated indium phosphide quantum dot for matrix metalloproteinase-2 cancer transformation sensing.”, Nanomedicine (London, England), 14(14):1791-1804.
  • Chang WM, Chang YC, Yang YC, Lin SK, Chang MH, Hsiao M*, 2019, “AKR1C1 controls cisplatin-resistance in head and neck squamous cell carcinoma through cross-talk with the STAT1/3 signaling pathway”, Journal of Experimental & Clinical Research, 38, 245.
  • Chien MH, Lin YW, Wen YC, Yang YC, Hsiao M, Chang JL, Huang HC, Lee WJ, 2019, “Targeting the SPOCK1-snail/slug axismediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis”, Journal of Experimental & Clinical Cancer Research, 38:246. (SCIE)
  • Lin TC, Yeh YM, Fan WL, Chang YC, Lin WM, Yang TY, Hsiao M*, 2019, “Ghrelin upregulates oncogenic Aurora A to promote renal cell carcinoma invasion”, Cancers, 11(3), 303. (SCIE)
  • Yeh CN, Chen MH, Chang YC, Wu RC, Tsao LC, Wang SY, Cheng CT, Chiang KC, Chen TW, Hsiao M, Weng WH, 2019, “Over-expression of TNNI3K is associated with early-stage carcinogenesis of cholangiocarcinom”, Molecular Carcinogenesis, 58(2), 270-278. (SCIE)
  • Chuang PK, Hsiao M, Hsu TL, Chang CF, Wu CY, Chen BR, Huang HW, Liao KS, Chen CC, Chen CL, Yang SM, Kuo CW, Chen P, Chiu PT, Chen IJ, Lai JS, Yu CT, Wong CH*, 2019, “Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer”, Proceedings of the National Academy of Sciences of the United States of America, 116(9), 3518-3523. (SCIE)
  • Jan YH, Lai TC, Yang CJ, Lin YF, Huang MS, Hsiao M*, 2019, “Adenylate kinase-4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis”, Journal of Hematology and Oncology, 12(1):12, Cite 3. (SCIE)
  • Chuang HH , Wang PH , Niu SW, Zhen YY, Huang MS, Hsiao M, Yang CJ, 2019, “Inhibition of FAK signaling elicits Lamin A/C-associated nuclear deformity and cellular senescence”, Frontiers in Oncology, 9:22. (SCIE)

Hsieh, Shie-Liang

  • Chen MH, Huang MT, Yu WK, Lee SS, Wang JH, Cheng TR, Bowman MR, Hsieh SL*, 2019, “Antibody blockade of Dectin-2 suppresses house dust mite-induced Th2 cytokine production in dendritic cell- and monocyte-depleted peripheral blood mononuclear cell co-cultures from asthma patients”, JOURNAL OF BIOMEDICAL SCIENCE, 26(1), 97. (SCIE)
  • Sung PS, Hsieh SL*, 2019, “CLEC2 and CLEC5A: Pathogenic Host Factors in Acute Viral Infections”, FRONTIERS IN IMMUNOLOGY, 10: 2867, 1-9. (SCIE)
  • Sung PS, Huang TF, Hsieh SL*, 2019, “Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2”, NATURE COMMUNICATIONS, 10(1): 2402, 1-13. (SCIE)

Hwang-Verslues, Wendy W.

  • Fararjeh, A., Tu, S.H., Chen, L.C., Cheng, T.C., Liu, Y.R., Chang, H.L., Chang, H.W., Huang, C.C., Wang, H.C.R., Hwang-Verslues, W.W., Wu, C.H., Ho, Y.S.*, 2019, “Long-term exposure to extremely low-dose of nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induce non-malignant breast epithelial cell transformation through activation of the a9-nicotinic acetylcholine receptor-mediated signaling pathway”, ENVIRONMENTAL TOXICOLOGY, 34(1), 73-82. (SCIE)

Lee, Wen-Hwa

  • Hsu JL, Chou JW, Chen TF, Hsu JT, Su FY, Lan JL, Wu PC, Hu CM, Lee EY, Lee WH, 2019, “Glutathione peroxidase 8 negatively regulates caspase-4/11 to protect against colitis.”, EMBO Molecular Medicine, 12(1), e9386. (SCIE)
  • Hu CM, Tien SC, Hsieh PK, Jeng YM, Chang MC, Chang YT, Chen YJ, Chen YJ, Lee EYP, Lee WH, 2019, “High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells.”, Cell metabolism, 29(6), 1334-1349.e10. (SCIE)
  • Peng HY, Chang MC, Hu CM, Yang HI, Lee WH, Chang YT, 2019, “Thrombospondin-2 is a Highly Specific Diagnostic Marker and is Associated with Prognosis in Pancreatic Cancer.”, Annals of surgical oncology, 26(3), 807-814. (SCIE)

Lin, Kuo-I

  • Liu, C.-H., Raj, S, Chen, C.-H., Hung, K.-H., Chou, C.-T., Chen, I.-Ho., Chien, J.-T., Lin, I-Y., Yang, S.-Y., Angata, T., Tsai, W.-C., Wei. J. C.-C., Tzeng, I-S., Hung, S.-C.*, and Lin, K.-I*, 2019, “HLA-B27-mediated activation of TNAP phosphatase promotes pathogenic syndesmophyte formation in ankylosing spondylitis”, JOURNAL OF CLINICAL INVESTIGATION, 129 (12): 5357-5373. (SCIE)
  • Tsai, D.-Y., Hung, K.-H., Chang, C.-W., and Lin, K.-I*, 2019, “Regulatory Mechanisms of B cell responses and the implication in B cell-related diseases”, JOURNAL OF BIOMEDICAL SCIENCE, 26(1):64. (SCIE)
  • Wang, Y.-H., Tsai, D.-Y., Ko, Y.-A., Yang, T.-T., Lin, I-Y., Hung, K.-H., and Lin, K.-I*, 2019, “Blimp-1 contributes to the development and function of regulatory B cells”, FRONTIERS IN IMMUNOLOGY, 10:1909. (SCIE)
  • Tseng, Y,-C., Wu, C.-Y., Liu, M.-L., Chen, T.-H., Chinag, W.-L., Yu, Y.-H., Jan, J.-T., Lin, K.-I, Wong, C.-H., and Ma, C., 2019, “Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections.”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116 (10) ,4200-4205. (SCIE)

Lu, Joyce Jean

  • Kuan II, Lee CC, Chen CH, Lu J, Kuo YS, Wu HC, 2019, “The extracellular domain of epithelial cell adhesion molecule (EpCAM) enhances multipotency of mesenchymal stem cells through EGFR-LIN28-LET7 signaling.”, The Journal of biological chemistry, 294(19), 7769-7786. (SCIE)

Shen, Chia-Ning

  • Lee, H.L., J.T.Tsai, C.Y. Chen, Y.C. Lin, C.B. Ho, L.L.Ting, C.C. Kuo, I.C. Lai, C.Y. Lin, J.H.Tang, Y.M. Huang, W.Y. Kao, S.W. Cheng, C.N. Shen*, S.W.Chen*, J.F. Chiou*, 2019, “Effectiveness of stereotactic ablative radiotherapy in patients with advanced hepatocellular carcinoma unsuitable for transarterial chemoembolization”, Therapeutic Advances in Medical Oncology, 11, 1758835919889002. (SCIE)
  • Shen CN, Goh KS, Huang CR, Chiang TC, Lee CY, Jeng YM, Peng SJ, Chien HJ, Chung MH, Chou YH, Hsieh CC, Kulkarni S, Pasricha PJ, Tien YW, Tang SC, 2019, “Lymphatic vessel remodeling and invasion in pancreatic cancer progression.”, EBioMedicine, 47, 98-113. (SCIE)

Yang, Hwai-I

  • Liu J, Hu HH, Chang CL, Jen CL, Lee MH, Lu SN, Wang LY, Yuan Q, Xia NS, Sugiyama M, Nishida N, Mizokami M, Chen CJ, Chen PJ, Yang HI*, 2019, “Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection.”, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 17(7):1413-1415. (SCIE)
  • Kong Y, Jia J, Yang HI*, 2019, “Lower Risk of Hepatocellular Carcinoma With Tenofovir vs Entecavir in Patients With Chronic Hepatitis B.”, JAMA oncology, 5(6):915-916. (SCIE)
  • Lin SH, Huang YT, Yang HI, 2019, “On identification of agonistic interaction: Hepatitis B and C interaction on hepatocellular carcinoma.”, Statistics in medicine, 38(13),2467-2476. (SCIE)
  • Peng HY, Chang MC, Hu CM, Yang HI, Lee WH, Chang YT, 2019, “Thrombospondin-2 is a Highly Specific Diagnostic Marker and is Associated with Prognosis in Pancreatic Cancer.”, Annals of surgical oncology, 26(3),807-814. (SCIE)
  • Yeo YH, Ho HJ, Yang HI, Tseng TC, Hosaka T, Trinh HN, Kwak MS, Park YM, Fung JYY, Buti M, Rodriguez M, Treeprasertsuk S, Preda CM, Ungtrakul T, Charatcharoenwitthaya P, Li X, Li J, Zhang J, Le MH, Wei B, Zou B, Le A, Jeong D, Chien N, Kam L, Lee CC, Riveiro-Barciela M, Istratescu D, Sriprayoon T, Chong Y, Tanwandee T, Kobayashi M, Suzuki F, Yuen MF, Lee HS, Kao JH, Lok AS, Wu CY, Nguyen MH, 2019, “Factors Associated with Rates of HBsAg Seroclearance in Adults with Chronic HBV Infection: A systematic review and meta-analysis.”, Gastroenterology, 156(3):635-646. (SCIE)
  • Hu HH, Liu J, Chang CL, Jen CL, Lee MH, Lu SN, Wang LY, Quan Y, Xia NS, Chen CJ, Chen PJ*, Yang HI*, 2019, “Level of hepatitis B (HB) core antibody associates with seroclearance of HBV DNA and HB surface antigen in HB e antigen-seronegative patients.”, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 17(1):172-181. (SCIE)
  • Nguyen MH, Yang HI, Le A, Henry L, Nguyen N, Lee MH, Zhang J, Wong C, Wong C, Trinh H, 2019, “Reduced Incidence of Hepatocellular Carcinoma with Tenofovir in Chronic Hepatitis B Patients with and without Cirrhosis - a Propensity Score Matched Study.”, The Journal of infectious diseases, 219(1):10-18. (SCIE)
  • Chien RN, Kao JH, Peng CY, Chen CH, Liu CJ, Huang YH, Hu TH, Yang HI, Lu SN, Ni YH, Chuang WL, Lee CM, Wu JC, Chen PJ, Liaw YF, 2019, “Taiwan consensus statement on the management of chronic hepatitis B.”, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 118(1):7-38. (SCIE)
  • Wen YH, Yang HI, Chou HC, Chen CY, Hsieh WS, Tsou KI, Tsao PN, 2019, “Association of Maternal Preeclampsia with Neonatal Respiratory Distress Syndrome in Very-Low-Birth-Weight Infants.”, Scientific reports, 9(1), 13212. (SCIE)
  • Huang CF, Iio E, Jun DW, Ogawa E, Toyoda H, Hsu YC, Haga H, Iwane S, Enomoto M, Lee DH, Wong G, Liu CH, Tada T, Chuang WL, Cheung R, Hayashi J, Tseng CH, Yasuda S, Tran S, Kam L, Henry L, Jeong JY, Nomura H, Park SH, Nakamuta M, Huang JF, Tai CM, Lo GH, Lee MH, Yang HI, Kao JH, Tamori A, Eguchi Y, Ueno Y, Furusyo N, Tanaka Y, Yu ML, Nguyen MH, 2019, “Direct-acting antivirals in East Asian hepatitis C patients: real-world experience from the REAL-C Consortium.”, Hepatology international, 13(5), 587-598. (SCIE)
  • Jeng WJ, Yang HI*, 2019, “Discrepant range of sPD-1 in different studies of chronic hepatitis B. A letter in response to Soluble programmed death-1 is a useful indicator for inflammatory and fibrosis severity in chronic hepatitis B.”, Journal of viral hepatitis, 26(7), 930. (SCIE)
  • Ogawa E, Toyoda H, Iio E, Jun DW, Huang CF, Enomoto M, Hsu YC, Haga H, Iwane S, Wong G, Lee DH, Tada T, Liu CH, Chuang WL, Hayashi J, Cheung R, Yasuda S, Tseng CH, Takahashi H, Tran S, Yeo YH, Henry L, Barnett SD, Nomura H, Nakamuta M, Dai CY, Huang JF, Yang HI, Lee MH, Jung Jun M, Kao JH, Eguchi Y, Ueno Y, Tamori A, Furusyo N, Yu ML, Tanaka Y, Nguyen MH, Ahn SB, Azuma K, Dohmen K, Yoon Jeong J, Jung JH, Kajiwara E, Kato M, Kawano A, Koyanagi T, Ooho A, Park SH, Satoh T, Shimoda S, Song DS, Takahashi K, Yeh ML, Yoon EL, 2019, “HCV Cure Rates are Reduced in Patients with Active but not Inactive Hepatocellular Carcinoma- A Practice Implication.”, Clinical Infectious Diseases, 71(11), 2840-2848. (SCIE)
  • Teng W, Jeng WJ, Yang HI, Chen WT, Hsieh YC, Huang CH, Lin CC, Lin CY, Lin SM, Sheen IS, 2019, “Interferon Is Superior to Direct Acting Antiviral Therapy in Tertiary Prevention of Early Recurrence of Hepatocellular Carcinoma.”, Cancers, 12(1), 23. (SCIE)
  • Irham LM, Wong HS, Perwitasari DA, Chou WH, Yang HI*, Chang WC*, 2019, “Single-nucleotide polymorphism of rs7944135 (macrophage-expressed gene 1) is associated with hepatitis B surface antigen seroclearance in chronic hepatitis B infection: A cohort study.”, Medicine, 98(51), e17936. (SCIE)
  • Hsu YC, Wong GL, Chen CH, Peng CY, Yeh ML, Cheung KS, Toyoda H, Huang CF, Trinh H, Xie Q, Enomoto M, Liu L, Yasuda S, Tanaka Y, Kozuka R, Tsai PC, Huang YT, Wong C, Huang R, Jang TY, Hoang J, Yang HI, Li J, Lee DH, Takahashi H, Zhang JQ, Ogawa E, Zhao C, Liu C, Furusyo N, Eguchi Y, Wong C, Wu C, Kumada T, Yuen MF, Yu ML, Nguyen MH, 2019, “Tenofovir Versus Entecavir for Hepatocellular Carcinoma Prevention in an International Consortium of Chronic Hepatitis B.”, The American journal of gastroenterology, 115(2), 271-280. (SCIE)
  • Liu SY, Yang HI, Chen CY, Chou HC, Hsieh WS, Tsou KI, Tsao PN, 2019, “The gestational effect of antenatal corticosteroids on respiratory distress syndrome in very low birth weight infants: A population-based study.”, Journal of the Formosan Medical Association, 119(8), 1267-1273. (SCIE)