| 2025 |
Chuang PK, Chung C, Liao KS, (Wong CH)*, Improving the efficacy of anti-SSEA4 antibody in pancreatic cancer immunotherapy with glyco-optimization and immune checkpoint blockade., Proceedings of the National Academy of Sciences of the United States of America, vol. 122(38), e2517415122, 2025任職中研院著作;
|
| 2025 |
J. M. Lo, C.-C. Kung, T.-J., C.-H. Wong, C. Ma, Structure-Based Mechanism and Specificity of Human Galactosyltransferase β3GalT5, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 147, 10875-10885, 2025具代表性; 任職中研院著作;
|
| 2025 |
C.-C. Kung, J. Lo, K.-S. Liao, C.-Y. Wu, L.-C. Cheng, C. Chung, T.-L. Hsu, C. Ma, C.-H. Wong, Expression of Human β3GalT5-1 in Insect Cells as Active Glycoforms for the Efficient Synthesis of Cancer-Associated Globo-Series Glycans, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 147, 10864-10874, 2025具代表性; 任職中研院著作;
|
| 2025 |
R. Li, P. Chen, Y.-F. Zeng, T.-H. Tseng, V. Gannedi, L. Krasnova, C.-H. Wong, Expedient Assembly of Multiantennary N-Glycans from Common N-Glycan Cores with Orthogonal Protection for the Profiling of Glycan-Binding Proteins., Journal of the American Chemical Society, vol. 147(15), 12937-12948, 2025具代表性; 任職中研院著作;
|
| 2025 |
K.-S. Liao, Y. Zhou, C. Chung, C.-C. Kung, C.-T. Ren, C.-Y. Wu, Y.-W. Lou, P.-K. Chuang, B. Imre, Y.S.Y. Hsieh, C.-H. Wong, Chemical and Enzymatic Synthesis of DisialylGb5 and Other Sialosides for Glycan Array Assembly and Evaluation of Siglec-Mediated Immune Checkpoint Inhibition., Molecules (Basel, Switzerland), vol. 30(11), 2264, 2025任職中研院著作;
|
| 2025 |
H.-W. Huang, Y.-F. Zeng, V. S. Shivatare, T.-H. Tseng, C.-H. Wong, Cell-based glycoengineering for production of homogeneous and specific glycoform enriched antibodies with improved effector functions, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 122 (8), e2423853122, 2025具代表性; 任職中研院著作;
|
| 2025 |
M. Usama, Y.-C. Hsu, M. Safaei, C.-Y. Chen, K.-H. Han, Y.-S. Ho, H. Yamaguchi, Y.-C. Li, M.-C. Hung, C.-H. Wong, C.-W. Lin, Antibody-drug conjugates targeting SSEA-4 inhibits growth and migration of SSEA-4 positive breast cancer cells., Cancer letters, vol. 611, 217453, 2025任職中研院著作;
|
| 2024 |
H.-H. Lin, C.-H. Wang, S.-H. Huang, S.-Y. Lin, T. Kato, K. Namba, N. Hosogi, C. song, K. Murata, C.-H. Yen, T.-L. Hsu, C.-H. Wong, Y.-M. Wu, I.-P. Tu, W.-H. Chang, Use of phase plate cryo-EM reveals conformation diversity of therapeutic IgG with 50 kDa Fab fragment resolved below 6 Å., Scientific reports, vol. 14(1), 14079, 2024任職中研院著作;
|
| 2024 |
C.-Y. Fan, S.-W. Wang, C. Chung, J.-Y. Chen, C.-Y. Chang, Y.-C. Chen, T.-L. Hsu, T.-R. Cheng, C.-H. Wong, Synthesis of a dendritic cell-targeted self-assembled polymeric nanoparticle for selective delivery of mRNA vaccines to elicit enhanced immune responses., Chemical science, vol. 15(29), 11626-11632, 2024具代表性; 任職中研院著作;
|
| 2024 |
N.-Y. Chen, C.-W. Lin, T.-Y. Lai, C.-Y. Wu, P.-C. Liao, T.-L. Hsu, C.-H. Wong, Increased expression of SSEA-4 on TKI-resistant non-small cell lung cancer with EGFR-T790M mutation., Proceedings of the National Academy of Sciences of the United States of America, vol. 121(5), e2313397121, 2024具代表性; 任職中研院著作;
|
| 2024 |
Chi-Huey Wong, Glycoengineering for a Universal COVID-19 Vaccine, Scientia, vol. Oct 30, 2024, e--pub, 2024任職中研院著作;
|
| 2024 |
M.-R. Kao, T.-H. Ma, H.-Y. Chou, S.-C. Chang, L.-C. Cheng, K.-S. Liao, J.-J. Shie, P.-J. Harris, C.-H. Wong, Y. S.-Y. Hsieh, A Robust α-l-Fucosidase from Prevotella nigrescens for Glycoengineering Therapeutic Antibodies., ACS chemical biology, vol. 19(7), 1515-1524, 2024任職中研院著作;
|
| 2024 |
K.-S. Liao, C.-C. Kung, L.-C. Cheng, C. Chung, C.-H. Wong, Synthesis and Quantitative Analysis of Glycans Conjugated to Gold Nanoparticles, Helvetica Chimica Acta, vol. online only, e202300209, 2024任職中研院著作;
|
| 2023 |
V.-S. Shivatare, P.-K. Chuang, T.-H. Tseng, Y.-F. Zeng, H.-W. Huang, G. Veeranjaneyulu, H.-C. Wu, (C.-H. Wong*, Study on antibody Fc-glycosylation for optimal effector functions., Chemical communications (Cambridge, England), vol. 59, 5555-5558, 2023具代表性; 任職中研院著作;
|
| 2023 |
H.-W. Huang, C.-C. Chen, K.-I. Lin, T.-L. Hsu, C.-H. Wong, Single Site N-Glycosylation of B Cell Maturation Antigen (BCMA) Inhibits gamma-Secretase-Mediated Shedding and Improves Surface Retention and Cell Survival., ACS chemical biology, vol. 19, 153-161, 2023任職中研院著作;
|
| 2023 |
V. S. Shivatare, H.-W. Huang, T.-H. Tseng, P.-K. Chuang, Y.-F. Zeng, C.-H. Wong, Probing the Internalization and Efficacy of Antibody‐Drug Conjugate via Site‐Specific Fc‐Glycan Labelling of a Homogeneous Antibody Targeting SSEA‐4 Bearing Tumors, Israel Journal of Chemistry, vol. Online, ahead of print, 2023任職中研院著作;
|
| 2023 |
S.-W. Wang, Y.-A. Ko, C.-Y. Chen, K.-S. Liao, Y.-H. Chang, H.-Y. Lee, Y.-H. Yu, Y.-H. Lih, Y.-Y. Cheng, H.-H. Lin, T.-L. Hsu, C.-Y. Wu, K.-I. Lin, (C.-H. Wong, Mechanism of Antigen Presentation and Specificity of Antibody Cross-Reactivity Elicited by an Oligosaccharide-Conjugate Cancer Vaccine., Journal of the American Chemical Society, vol. 145(17), 9840-9849, 2023具代表性; 任職中研院著作;
|
| 2023 |
C.-W. Cheng, C.-Y. Wu, S.-W. Wang, J.-Y. Chen, C.-C. Kung, K.-S. Liao, C.-H. Wong, Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA)., Proceedings of the National Academy of Sciences of the United States of America, vol. 120(49), e2314392120, 2023具代表性; 任職中研院著作;
|
| 2023 |
O. Chou, Y.-P. Juang, T.-L. Chao, S.-F. Tsai, P.-F. Chiu, C.-T. Chiou, K.-C. Tsai, S.-Y. Chang, P.-H. Liang, C.-H. Wong, Isolation of Anti-SARS-CoV-2 Natural Products Extracted from Mentha canadensis and the Semi-synthesis of Antiviral Derivatives, Journal of natural products, vol. 86(6), 1428-1436, 2023任職中研院著作;
|
| 2023 |
Y. Zhou, K.-S. Liao, T.-Y. Chen, Y. SY Hsieh, C.-H. Wong, Effective Organotin-Mediated Regioselective Functionalization of Unprotected Carbohydrates., The Journal of organic chemistry, vol. 88(11), 7141-7151, 2023任職中研院著作;
|
| 2023 |
Z.-R. Li, R. Li, L. Pasternack, P. Chen, C.-H. Wong, Chemical Synthesis of a Keto Sugar Nucleotide, The Journal of Organic Chemistry, vol. 88(11), 7580-7585, 2023任職中研院著作;
|
| 2023 |
C.-C. Chen, H.-W. Huang, B.-R. Chen, C.-H. Wong, Quantitative Mass Spectrometric Analysis of Hepatocellular Carcinoma Biomarker Alpha-Fetoprotein, RSC Chemical Biology, vol. published online ahead of print, published online ahead of print, 2023任職中研院著作;
|
| 2022 |
H.-Y. Huang, H.-Y. Liao, X. Chen, C.-W. Cheng, S.-W. Wang, M. Shahed-Al-Mahmud, T.-H. Chen, J. M. Lo, Y.-M. Liu, H.-H. Ma, Y.-H. Chang, C.-Y. Tsai, P.-Y. Huang, S.-Y. Chang, T.-L. Chao, H.-C. Kao, Y.-M. Tsai, Y.-H. Chen, C.-Y. Chen, K.-C. Lee, C.-Y. Wu, J.-T. Jan, T.-J. R. Cheng, K.-I. Lin*, C. Ma*, C.-H. Wong*, Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models., Science translational medicine, vol. 14(639), eabm0899, 2022具代表性; 任職中研院著作;
|
| 2022 |
C.-Y. Chen, Y.-W. Lin, S.-W. Wang, Y.-C. Lin, Y.-Y. Cheng, C.-T. Ren, (C.-H. Wong, C.-Y. Wu, Synthesis of Azido-Globo H Analogs for Immunogenicity Evaluation., ACS central science, vol. 8(1), 77-85, 2022任職中研院著作;
|
| 2022 |
C.-Y. Wu, C.-W. Cheng, C.-C. Kung, K.-S. Liao, J.-T. Jan, C. Ma, (C.-H. Wong*, Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine., Proceedings of the National Academy of Sciences of the United States of America, vol. 119(9), e2119995119, 2022任職中研院著作;
|
| 2022 |
S. S. Shivatare, V. S. Shivatare, C.-H. Wong, Glycoconjugates: Synthesis, Functional Studies, and Therapeutic Developments., Chemical reviews, vol. 122(20), 15603-15671, 2022任職中研院著作;
|
| 2022 |
K. Uchimura, K. Nishitsuji, L.-T. Chiu, T. Ohgita, H. Saito, F. Allain, V. Gannedi, (C.-H. Wong, S.-C. Hung, Design and Synthesis of 6-O-Phosphorylated Heparan Sulfate Oligosaccharides to Inhibit Amyloid beta Aggregation., Chembiochem : a European journal of chemical biology, vol. Epub ahead of print, e202200191, 2022任職中研院著作;
|
| 2022 |
Y.-Y. Tseng, J.-M. Liou, W.-C. Cheng, J.-T. Hsu, T.-L. Hsu, M.-S. Wu, C.-H. Wong, Combating multidrug-resistant Helicobacter pylori with moenomycin A in combination with clarithromycin or metronidazole., Frontiers in chemistry, vol. 10, 897578, 2022任職中研院著作;
|
| 2021 |
V. Gannedi, B. Villuri, S. Reddy, C.-C. Ku, C.-H. Wong, S.-C. Hung, Practical Remdesivir Synthesis through One-Pot Organocatalyzed Asymmetric (S)-P-Phosphoramidation., The Journal of organic chemistry, vol. 86(7), 4977–4985, 2021任職中研院著作;
|
| 2021 |
S. S. Shivatare, T.-J. Chen, Y.-Y. Cheng, V. S. Shivatare, T.-I. Tsai, H.-Y. Chaung, C.-Y. Wu, C.-H. Wong, Immunogenicity Evaluation of N-Glycans Recognized by HIV Broadly Neutralizing Antibodies., ACS chemical biology, vol. 16(10), 2016-2025, 2021任職中研院著作;
|
| 2021 |
J.-T. Jan, T.-J. R. Cheng, Y.-P. Juang, H.-H. Ma, Y.-T. Wu, W.-B. Yang, C.-W. Cheng, X. Chen, T.-H. Chou, J.-J. Shie, W.-C. Cheng, R.-J. Chein, S.-S. Mao, P.-H. Liang, C. Ma, S.-C. Hung, C.-H. Wong, Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection., Proceedings of the National Academy of Sciences of the United States of America, vol. 118(5), e2021579118, 2021任職中研院著作;
|
| 2021 |
C.-W. Lin, Y.-J. Wang, T.-Y. Lai, T.-L. Hsu, S.-Y. Han, H.-C. Wu, C.-N. Shen, V. Dang, M.-W. Chen, L.-B. Chen, C.-H. Wong, Homogeneous antibody and CAR-T cells with improved effector functions targeting SSEA-4 glycan on pancreatic cancer., Proceedings of the National Academy of Sciences of the United States of America, vol. 118(50), e-e2114774118, 2021任職中研院著作;
|
| 2021 |
R.-H. Lee, Y.-J. Wang, T.-Y. La, T.-L. Hsu, P.-K. Chuang, C.-H. Wong, Combined Effect of Anti-SSEA4 and Anti-Globo H Antibodies on Breast Cancer Cells., ACS chemical biology, vol. 16(8), 1526-1537, 2021任職中研院著作;
|
| 2021 |
C.-W. Chang, M.-H. Lin, C.-K. Chan, K.-Y. Su, C.-H. Wu, W.-C. Lo, S. Lam, Y.-T. Cheng, P.-H. Liao, C.-H. Wong, C.-C. Wang, Automated Quantification of Hydroxyl Reactivities: Prediction of Glycosylation Reactions., Angewandte Chemie (International ed. in English), vol. DOI: 10.1002/anie.202013909, 2021任職中研院著作;
|
| 2021 |
Y.-A. Ko, Y.-H. Yu, Y.-F. Wu, Y.-C. Tseng, C.-L. Chen, K.-S. Goh, H.-Y. Liao, T.-H. Chen, T.-J. R. Cheng, A.-S. Yang, C.-H. Wong, C. Ma, K.-I. Lin, A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells., PLoS pathogens, vol. 17(8), e1009724, 2021任職中研院著作;
|
| 2020 |
C.-F. Huang, W.-H. Chang, T.-K. Lee, Y. Joti, Y. Nishino, T. Kimura, A. Suzuki, Y. Bessho, T.-T. Lee, M.-C. Chen, S.-M. Yang, Y. Hwu, S.-H. Huang, P.-N. Lee, P. Chen, Y.-C. Tseng, C. Ma, T.-L. Hsu, C.-H. Wong, K. Tono, T. Ishikawa, K. Liang, XFEL coherent diffraction imaging for weakly scattering particles using heterodyne interference, AIP Advances, vol. 10(5), 055219, 2020任職中研院著作;
|
| 2020 |
L.-T. Chiu, N. Sabbavarapu, W.-C. Lin, C.-Y. Fang, C.-C. Wu, T.-J. Cheng, C.-H. Wong, S.-C. Hung, Trisaccharide Sulfate and Its Sulfonamide as an Effective Substrate and Inhibitor of Human Endo-O-sulfatase-1, Journal of the American Chemical Society, vol. 142(11), 5282-5292, 2020任職中研院著作;
|
| 2020 |
S. Shivatare, C.-H. Wong, Synthetic Carbohydrate Chemistry and Translational Medicine., The Journal of organic chemistry, vol. 85(24), 15780-15800, 2020任職中研院著作;
|
| 2020 |
S. Pawar, L. Hsu, T. N. Reddy, M. Ravinder, C.-T. Ren, Y.-W. Lin, Y.-Y. Cheng, T.-W. Lin, T.-L. Hsu, S.-K. Wang, C.-H. Wong, C.-Y. Wu, Synthesis of Asymmetric N-Glycans as Common Core Substrates for Structural Diversification through Selective Enzymatic Glycosylation, ACS Chemical Biology, vol. 15(9), 2382-2394, 2020任職中研院著作;
|
| 2020 |
C.-Y. Lin, H.-Y. Wu, P.-S. Wu, Y.-L. Hsu, T.-J. Cheng, J.-H. Liu, R.-J. Huang, T. H. Hsiao, C.-J. Wang, P.-F. Hung, A. Lan, Y.-J. Chen, S.-H. Pan, R.-J. Chein, C.-H. Wong, P.-C. Yang, Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein, Journal of Medicinal Chemistry, vol. 63(6), 3172-3187, 2020任職中研院著作;
|
| 2020 |
C.-W. Cheng, C.-Y. Wu, W.-L. Hsu, C.-H. Wong, Programmable One-Pot Synthesis of Oligosaccharides, Biochemistry, vol. 59(34), 3078-3088, 2020任職中研院著作;
|
| 2020 |
S. Dey, H.-J. Lo, C.-H. Wong, Programmable One-Pot Synthesis of Heparin Pentasaccharide Fondaparinux, Organic Letters, vol. 22(12), 4638-4642, 2020任職中研院著作;
|
| 2020 |
E. A. Wang, W.-Y. Chen, C.-H. Wong, Multiple Growth Factor Targeting by Engineered Insulin-like Growth Factor Binding Protein-3 Augments EGF Receptor Tyrosine Kinase Inhibitor Efficacy, Scientific Reports, vol. 10(1), 2735, 2020任職中研院著作;
|
| 2020 |
C.-Y. Wu, H.-Y. Chuang, C.-H. Wong, Influenza virus neuraminidase regulates host CD8(+) T-cell response in mice., Communications biology, vol. 3(1), 748, 2020任職中研院著作;
|
| 2020 |
W.-F. Wang, M.-Y. Jade Lu, T.-J. R. Cheng, Y.-C. Tang, Y.-C. Teng, T.-Y. Hwa, Y.-H. Chen, M.-Y. Li, M.-H. Wu, P.-C. Chuang, R. Jou, C.-H. Wong, W.-H. Li, Genomic Analysis of Mycobacterium tuberculosis Isolates and Construction of a Beijing Lineage Reference Genome, Genome Biology and Evolution, vol. 12(2), 3890-3905, 2020具代表性; 任職中研院著作;
|
| 2020 |
J. Woodring, S.-H. Lu, L. Krasnova, S.-C. Wang, J.-B. Chen, C.-C. Chou, Y.-C. Huang, T.-J. Cheng, Y.-T. Wu, Y.-H. Chen, J.-M. Fang, M.-D. Tsai, C.-H. Wong, Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein, Journal of Medicinal Chemistry, vol. 63(1), 205-215, 2020任職中研院著作;
|
| 2020 |
Y.-H. Chang, J.-C. Wu, H.-M. Yu, H.-T. Hsu, Y.-T. Wu, A. L.-T. Yu, C.-D. T. Yu, C.-H. Wong, Design and synthesis of glyco-peptides as anti-cancer agents targeting thrombin-protease activated receptor-1 interaction, Chemical Communications, vol. 56(43), 5827-5830, 2020任職中研院著作;
|
| 2020 |
H.-Y. Liao, S.-C. Wang, Y.-A. Koa, K.-I. Lin, C. Ma, T.-J. R. Cheng, C.-H. Wong, Chimeric hemagglutinin vaccine elicits broadly protective CD4 and CD8 T cell responses against multiple influenza strains and subtypes, Proceedings of the National Academy of Sciences, vol. 117(30), 17757-17763, 2020具代表性; 任職中研院著作;
|
| 2020 |
Y.-M. Liu, M. Shahed-Al-Mahmud, X. Chen, T.-H. Chen, K.-S. Liao, J. M. Lo, Y.-M Wu., M.-C. Ho, C.-Y. Wu, C.-H. Wong, J.-T. Jan, C. Ma, A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2, Cell Reports, vol. 32(6), 108016, 2020任職中研院著作;
|
| 2019 |
X. Chen, C.-H. Wong, C. Ma, Targeting the Bacterial Transglycosylase: Antibiotic Development from a Structural Perspective, ACS Infectious Diseases, vol. 5(9), 1493-1504, 2019任職中研院著作;
|
| 2019 |
M.-R. Huang, Y.-L. Hsu, T.-C. Lin, T.-J. Cheng, L.-W. Li, W.-W. Tseng, Y.-S. Chou, J.-H. Liu, S.-H. Pan, J.-M. Fang, C.-H. Wong, Structure-guided development of purine amide, hydroxamate, and amidoxime for the inhibition of non-small cell lung cancer, European Journal of Medicinal Chemistry, vol. 181, 111551, 2019任職中研院著作;
|
| 2019 |
C.-H. Wong, L. Krasnova, Highlights in chemical glycobiology, Israel Journal of Chemistry, vol. 59, 18-22, 2019任職中研院著作;
|
| 2019 |
M.-S. Lin, T.-M. Hong, T.-H. Chou, S.-C. Yang, M.-C. Chung, C.-W. Weng, M.-L. Tsai, T.-R. Cheng, J.-J.-W., T.-C. Lee, C.-H. Wong, R.-J. Chein, P.-C. Yang, Hierarchical and Programmable One-Pot Oligosaccharide Synthesis, Journal of Visualized Experiments, vol. 151, e59987, 2019任職中研院著作;
|
| 2019 |
S. Dey, H.-J. Lo, C.-H. Wong, An Efficient Modular One-Pot Synthesis of Heparin-Based Anticoagulant Idraparinux, Journal of the American Chemical Society, vol. 141(26), 10309-10314, 2019任職中研院著作;
|
| 2019 |
M.-S. Lin, T.-M. Hong, T.-H. Chou, S.-C. Yang, M.-C. Chung, C.-W. Weng, M.-L. Tsai, T.-R. Cheng, J.-J.-W., T.-C. Lee, C.-H. Wong, R.-J. Chein, P.-C. Yang, 4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin, European Journal of Medicinal Chemistry, vol. 181, 111584, 2019任職中研院著作;
|
| 2019 |
S.-C. Wang, H.-Y. Liao, J.-Y. Zhang, T.-J. R. Cheng, C.-H. Wong, Development of a universal influenza vaccine using hemagglutinin stem protein produced from Pichia pastoris, VIROLOGY, vol. 526, 125-137, 2019任職中研院著作;
|
| 2019 |
P.-K. Chuang, M. Hsiao, T.-L. Hsu, C.-F. Chang, C.-Y. Wu, B.-R. Chen, H.-W. Huang, K.-S. Liao, C.-C. Chen, C.-L. Chen, S.-M. Yang, C. W. Kuo, P. Chen, P.-T. Chiu, I.-J. Chen, J.-S. Lai, C.-D. T. Yu, C.-H. Wong, Signaling pathway of globo-series glycosphingolipids and beta1,3-galactosyltransferase V (beta3GalT5) in breast cancer., Proceedings of the National Academy of Sciences of the United States of America, vol. 116 (9), 3518-3523, 2019任職中研院著作;
|
| 2019 |
L. Krasnova, C.-H. Wong, Oligosaccharide Synthesis and Translational Innovation., Journal of the American Chemical Society, vol. 141(9), 3735-3754, 2019具代表性; 任職中研院著作;
|
| 2019 |
Y.-C. Tseng, C.-Y. Wu, M.-L. Liu, T.-H. Chen, W.-L. Chiang, Y.-H. Yu, J.-T. Jan, K.-I. Lin, C.-H. Wong, C. Ma, Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections., Proceedings of the National Academy of Sciences of the United States of America, vol. 116(10), 4200-4205, 2019具代表性; 任職中研院著作;
|
| 2019 |
H.-J. Lo, L. Krasnova, S. Dey, T. Cheng, H. Liu, T.-I. Tsai, K. B. Wu, C.-Y. Wu, C.-H. Wong, Synthesis of Sialidase-Resistant Oligosaccharide and Antibody Glycoform Containing alpha2,6-Linked 3F(ax)-Neu5Ac., Journal of the American Chemical Society, vol. 141(16), 6484-6488, 2019具代表性; 任職中研院著作;
|
| 2018 |
V. S. Shivatare, S. S. Shivatare, C.-C. Lee, C.-H. Liang, K.-S. Liao, Y.-Y. Cheng, G. Saidachary, C.-Y. Wu, N.-H. Lin, P. D. Kwong, D. Burton, C.-Y. Wu, C.-H. Wong, Unprecedented Role of Hybrid N-Glycans as Ligands for HIV-1 Broadly Neutralizing Antibodies., Journal of the American Chemical Society, vol. 140(15), 5202-5210, 2018任職中研院著作;
|
| 2018 |
X. Wang, L. Krasnova, K. B. Wu, W.-S. Wu, T.-J. Cheng, C.-H. Wong, Towards new antibiotics targeting bacterial transglycosylase: Synthesis of a Lipid II analog as stable transition-state mimic inhibitor., Bioorganic & Medicinal Chemistry Letters, vol. 28(16 SI), 2708-2712, 2018任職中研院著作;
|
| 2018 |
S. Dey, S. O. Bajaj, T.-I. Tsai, H.-J. Lo, K. Wu, C.-H. Wong, Synthesis of Modular Building Blocks using Glycosyl Phosphate Donors for the Construction of Asymmetric N-Glycans, TETRAHEDRON, vol. 74(41), 6003-6011, 2018任職中研院著作;
|
| 2018 |
S. Dey, C.-H. Wong, Programmable one-pot synthesis of heparin pentasaccharides enabling access to regiodefined sulfate derivatives, Chemical Science, vol. 9(32), 6685-6691, 2018任職中研院著作;
|
| 2018 |
P.-W. Lo, J.-J. Shie, C.-H. Chen, C.-Y. Wu, T.-L. Hsu, C.-H. Wong, O-GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2, Proceedings of the National Academy of Sciences of the United States of America, vol. 115 (28), 7302-7307, 2018任職中研院著作;
|
| 2018 |
C.-W. Cheng, Y. Zhou, W.-H. Pan, S. Dey, C.-Y. Wu, W.-L. Hsu, C.-H. Wong, Hierarchical and programmable one-pot automated synthesis of oligosaccharides, Nature Communications, vol. 9, 5202, 2018任職中研院著作;
|
| 2018 |
C.-P. Liu, T.-I Tsai, T. Cheng, V. S. Shivatare, C.-Y. Wu, C.-Y. Wu, C.-H. Wong, Glycoengineering of antibody (Herceptin) through yeast expression and in vitro enzymatic glycosylation., Proceedings of the National Academy of Sciences of the United States of America, vol. 115(4), 720-725, 2018任職中研院著作;
|
| 2018 |
C.-F. Huang, K. S. Liang, T.-L. Hsu, T.-T. Lee, Y.-Y. Chen, S.-M. Yang, H.-H. Chen, S.-H. Huang, W.-H. Chang, T.-K. Lee, P. Chen, K.-E. Peng, C.-C. Chen, C.-Z. Shi, Y.-F. Hu, G. Margaritondo, T. Ishikawa, C.-H. Wong, Y. Hwu, Free-electron-laser coherent diffraction images of individual drug-carrying liposome particles in solution., Nanoscale, vol. 10(6), 2820-2824, 2018任職中研院著作;
|
| 2018 |
S. S. Shivatare, L.-Y. Huang, Y.-F. Zeng, J.-Y. Liao, T.-H. You, S.-Y. Wang, T. Cheng, C.-W. Chiu, P. Chao, L.-T. Chen, T.-I. Tsai, C.-C. Huang, C.-Y. Wu, N.-H. Lin, C.-H. Wong, Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies, CHEMICAL COMMUNICATIONS, vol. 54(48), 6161-6164, 2018任職中研院著作;
|
| 2018 |
S. S. Shivatare, V. S. Shivatare, C.-Y. Wu, C.-H. Wong, Chemo-Enzymatic Synthesis of N-Glycans for Array Development and HIV Antibodies Profiling, Jove-Journal of Visualized Experiments, vol. 132, 2018任職中研院著作;
|
| 2018 |
W.-S. Wu, W.-C. Cheng, T.-R. Cheng, C.-H. Wong, Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase., Journal of the American Chemical Society, vol. 140 (8), 2752-2755, 2018任職中研院著作;
|
| 2018 |
T. Zhou, A. Zheng, U. Baxa, G.-Y. Chuang, I. S. Georgiev, R. Kong, S. O’Dell, S. Shahzad-ul-Hussan, C.-H. Shen, Y. Tsybovsky, R. T. Bailer, S. K. Gift, M. K. Louder, K. McKee, R. Rawi, C. H. Stevenson, G. B. E. Stewart-Jones, J. D. Taft, E. Waltari, Y. Yang, B. Zhang, S. S. Shivatare, V. S. Shivatare, C.-C. D. Lee, C.-Y. Wu, NISC Comparative Sequencing Program, J. C. Mullikin, C. A. Bewley, D. R. Burton, V. R. Polonis, L. Shapiro, C.-H. Wong, J. R. Mascola, P. D. Kwong, X. Wu, A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope., Immunity, vol. 48(3), 500-513.e6, 2018任職中研院著作;
|
| 2018 |
H.-W. Cheng, R.-J. Chein, T.-J. Cheng, P.-S. Wu, H.-Y. Wu, P.-F. Hung, C.-J. Wang, Y.-L. Hsu, J.-M. Wong, A. Yuan, C.-H. Wong, P.-C. Yang, S.-H. Pan, 2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction., Cancer science, vol. 109(3), 832-842, 2018任職中研院著作;
|
| 2017 |
L.-Y. Huang, S.-C. Wang, T.-J. R. Cheng, C.-H. Wong, Undecaprenyl Phosphate Phosphatase Activity of Undecaprenol Kinase Regulates the Lipid Pool in Gram-Positive Bacteria., Biochemistry, vol. 56(40), 5417-5427, 2017任職中研院著作;
|
| 2017 |
T. H. Tseng, T.-W. Lin, C.-Y. Chen, C.-H. Chen, J.-L. Lin, T.-L. Hsu, C.-H. Wong, Substrate Preference and Interplay of Fucosyltransferase 8 and N-Acetylglucosaminyltransferases., Journal of the American Chemical Society, vol. 139(28), 9431-9434, 2017任職中研院著作;
|
| 2017 |
Y.-W. Huang, H.-I. Yang, Y.-T. Wu, T.-L. Hsu, T.-W. Lin, J. Kelly, C.-H. Wong, Residues Comprising the Enhanced Aromatic Sequon Influence Protein N-Glycosylation Efficiency., Journal of the American Chemical Society, vol. 139(37), 12947-12955, 2017任職中研院著作;
|
| 2017 |
R. Andrabi, C.-Y. Su, C.-H. Liang, S.-S. Shivatare, B. Briney, J. E. Voss, S. K. Nawazi, C.-Y. Wu, C.-H. Wong, D. R. Burton, Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development., Immunity, vol. 47(5), 1004, 2017任職中研院著作;
|
| 2017 |
C.-Y. Ting, Y.-W. Lin, C.-Y. Wu, C.-H. Wong, Design of Disaccharide Modules for a Programmable One-Pot Synthesis of Building Blocks with LacNAc Repeating Units for Asymmetric N-Glycans, Asian Journal of Organic Chemistry, vol. 6(12), 1800-1807, 2017任職中研院著作;
|
| 2017 |
A. M. Stax, J. Tuengel, E. Girardi, N. Kitano, L. L. Allan, J. I. Alvarez, V. Li, D. Zheng, W. J. Panenka, C.-H. Wong, S. van Calenbergh, D. M. Zajonc, P. van den Elzen, Autoreactivity to Sulfatide by Human Invariant NKT Cells., JOURNAL OF IMMUNOLOGY, vol. 199(1), 97-106, 2017任職中研院著作;
|
| 2017 |
C.-Y. Wu, C.-W. Lin, T.-L. Tsai, C.-C. D. Lee, H.-Y. Chuang, J.-B. Chen, M.-H. Tsai, B.-R. Chen, P.-W. Lo, C.-P. Liu, V. S. Shivatare, C.-H. Wong, Influenza A surface glycosylation and vaccine design., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 114(2), 280-285, 2017任職中研院著作;
|
| 2017 |
T.-I. Tsai, S.-T. Li, C.-P. Liu, K. Chen, S. S. Shivatare, C.-W. Lin, S.-F. Liao, C.-W. Lin, T.-L. Hsu, Y.-T. Wu, M.-H. Tsai, M-Y. Lai, N.-H. Lin, C.-Y. Wu, C.-H. Wong, An Effective Bacterial Fucosidase for Glycoprotein Remodeling, ACS Chemical Biology, vol. 12(1), 63-72, 2017任職中研院著作;
|
| 2017 |
J.-J. Shie, Y.-C. Liu, J.-C. Hsiao, J.-M. Fang, C.-H. Wong, A cell-permeable and triazole-forming fluorescent probe for glycoconjugate imaging in live cells, CHEMICAL COMMUNICATIONS, vol. 53(9),1490-1493, 2017任職中研院著作;
|
| 2017 |
W. Yang, D. Punyadarsaniya, R. Lambertz, D. Lee, C.-H. Liang, D. Höper, S. Leist, A. Hernandez-Caceres, J. Stech, M. Beer, C.-Y. Wu, C.-H. Wong, K. Schughart, F. Meng, G. Herrler, Mutations during the Adaptation of H9N2 Avian Influenza Virus to the Respiratory Epithelium of Pigs Enhance Sialic Acid Binding Activity and Virulence in Mice, JOURNAL OF VIROLOGY, vol. 91(8), e02125-16, 2017任職中研院著作;
|
| 2017 |
C.-L. Chen, J.-C. Hsu, C.-W. Lin, C.-H. Wang, M.-H. Tsai, C.-Y. Wu, C.-H. Wong, C. Ma, Crystal structure of a homogeneous IgG-Fc glycoform with the N-glycan designed to maximize the antibody dependent cellular cytotoxicity, ACS Chemical Biology, vol. 12(5), 1335-1345, 2017任職中研院著作;
|
| 2017 |
Y. Kizuka, M. Nakano, Y. Yamaguchi, K. Nakajima, R. Oka, K. Sato, C.-T. Ren, T.-L. Hsu, C.-H. Wong, N. Taniguchi, An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA3., Cell chemical biology, vol. 24(12), 1467-1478.e5, 2017任職中研院著作;
|
| 2016 |
L. Krasnova, C.-H. Wong, Understanding the Chemistry and Biology of Glycosylation with Glycan Synthesis, Annual Review of Biochemistry, vol. 85, 599-630, 2016任職中研院著作;
|
| 2016 |
G. B. E. Stewart-Jones, C. Soto, T. Lemmin, G.-Y. Chuang, A. Druz, R. Kong, P. V. Thomas, K. Wagh, T. Zhou, A.-J. Behrens, T. Bylund, C. W. Choi, J. R. Davison, I. S. Georgiev, M. G. Joyce, Y. D. Kwon, M. Pancera, J. Taft, Y. Yang, B. Zhang, S. S. Shivatare, V. S. Shivatare, C.-C. D. Lee, C.-Y. Wu, C. A. Bewley, D. R. Burton, W. C. Koff, M. Connors, M. Crispin, B. T. Korber, C.-H. Wong, J. R. Mascola, P. D. Kwong, Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G., Cell, vol. 165(4), 813-826, 2016任職中研院著作;
|
| 2016 |
C.-H. Hsu, S. Park, D. E. Mortenson, B. L. Foley, X. Wang, R. J. Woods, D. A. Case, E. T. Powers, C.-H. Wong, H. J. Dyson, J. W. Kelly, The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate., Journal of the American Chemical Society, vol. 138(24), 7636-7648, 2016任職中研院著作;
|
| 2016 |
S. K. C. Cheung, P.-K. Chuang, H.-W. Huang, W. W. Hwang-Verslues, C. H.-H. Cho, W.-B. Yang, C.-N. Shen, M. Hsiao, T.-L. Hsu, C.-F. Chang, C.-H. Wong, Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells., Proceedings of the National Academy of Sciences of the United States of America, vol. 113(4), 960-965, 2016任職中研院著作;
|
| 2016 |
T.-C. Kuo, L.-W. Li, S.-H. Pan, J.-M. Fang, J.-H. Liu, T.-R. Cheng, C.-J. Wang, P.-F. Hung, H.-Y. Chen, T.-M. Hong, Y.-L .Hsu, C.-H. Wong, P.-C. Yan, Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin., JOURNAL OF MEDICINAL CHEMISTRY, vol. 59(18), 8521-8534, 2016任職中研院著作;
|
| 2016 |
T.-N. Wu, K.-H. Lin, Y.-T. Wu, J.-R. Huang, J.-T. Hung, J.-C. Wu, C.-Y. Chen, K.-C. Chu, N.-H. Lin, A. L.Yu, C.-H. Wong, Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation., ACS chemical biology, vol. 11(12), 3431-3441, 2016任職中研院著作;
|
| 2016 |
P.-C. Wang, J.-M. Fang, K.-C. Tsai, S.-Y. Wang, W.-I. Huang, Y.-S. Cheng, R. C., C.-H. Wong, Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors., Journal of medicinal chemistry, vol. 59(11), 5297-5310, 2016任職中研院著作;
|
| 2016 |
S. S. Shivatare, S.-H. Chang, T.-I. Tsai, S. Y. Tseng, Y.-S. Lin, Y.-Y. Cheng, C.-T. Ren, S. Pawar, C.-S. Tsai, H.-W. Shi, Y.-F. Zeng, C.-H. Liang, P. D. Kwong, D. R. Burton, C.-Y. Wu, C.-H. Wong, Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies, Nature Chemistry, vol. 8 (4), 338-346, 2016任職中研院著作;
|
| 2016 |
Y. Kizuka, S. Funayama, H. Shogomori, M. Nakano, K. Nakajima, R. Oka, S. Kitazume, Y. Yamaguchi, M. Sano, H. Korekane, T.-L. Hsu, H.-Y. Lee, C.-H. Wong, N. Taniguchi, High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery., Cell Chemical Biology, vol. 23(7), 782-792, 2016任職中研院著作;
|
| 2016 |
S.-C. Yeh, P.-Y. Wang, Y.-W. Lou, K.-H. Khoo, M. Hsiao, T.-L. Hsu, C.-H. Wong, Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity., Proceedings of the National Academy of Sciences of the United States of America, vol. 113(20), 5592-5597, 2016任職中研院著作;
|
| 2016 |
L. Krasnova, C.-H. Wong, Exploring human glycosylation for better therapies., MOLECULAR ASPECTS OF MEDICINE, vol. S0098-2997, 2016任職中研院著作;
|
| 2016 |
D. T. MacLeod, N. M. Choi, B. Briney, F. Garces, L. S. Ver, E. Landais, B. Murrell, T. Wrin, W. Kilembe, C.-H. Liang, A. Ramos, C.-B. Bian, L. Wickramasinghe, L. Kong, K. Eren, C.-Y. Wu, C.-H. Wong, S. L. Kosakovsky Pond, I. A. Wilson, D. R. Burton, P. Poignard, Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch., Immunity, vol. 44(5), 1215-1226, 2016任職中研院著作;
|
| 2016 |
Y.-L. Lo, G.-G. Liou, C.-H. Lu, M. Hsiao, T.-L. Hsu, C.-H. Wong, Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex., PloS one, vol. 11(11), e0166474, 2016任職中研院著作;
|
| 2016 |
D. Sok, M. Pauthner, B. Briney, J.-H. Lee, K. L.Saye-Francisco, J. Hsueh, A. Ramos, K.-M. Le, M. Jones, J. G. Jardine, R. Bastidas, A. Sarkar, C.-H. Liang, S. S. Shivatare, C.-Y. Wu, W. R. Schief, C.-H. Wong, I. A. Wilson, A. B. Ward, J. Zhu, P. Poignard, D. R. Burton, A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans., Immunity, vol. 45(1), 31-45, 2016任職中研院著作;
|
| 2016 |
S. Y. Tseng, W.-H. Cho, J. Su, S.-H. Chang, D. Chiang, C.-Y. Wu, C.-N. Hsiao, C.-H. Wong, Preparation of Aluminum Oxide-Coated Glass Slides for Glycan Microarrays, ACS Omega, vol. 1(5), 773–783, 2016任職中研院著作;
|
| 2015 |
C.-C. Tsai, C.-R. Lin, H.-Y. Tsai, C.-J. Chen, W.-T. Li, H.-M. Yu, Y.-Y. Ke, W.-Y. Hsieh, C.-Y. Chang, Y.-T. Wu, S.-T. Chen, C.-H. Wong, The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling, The Journal of biological chemistry, vol. 290(19), 11935, 2015任職中研院著作;
|
| 2015 |
S. K. C. Cheung, P.-K. Chuang, H.-W. Huang, W. W. Hwang-Verslues, C. H.-H. Cho, W.-B. Yang, C.-N. Shen, M. Hsiao, T.-L. Hsu, C.-F. Chang, C.-H. Wong, Stage-specific embryonic antigen-3 (SSEA-3) and beta3GalT5 are cancer specific and significant markers for breast cancer stem cells, Proceedings of the National Academy of Sciences of the United States of America, vol. 113(4), 960-965, 2015任職中研院著作;
|
| 2015 |
Y.-Y. Ke, C.-H. Tsai, H.-M. Yu, Y.-C. Jao, J.-M. Fang, C.-H. Wong, Latifolicinin A from a Fermented Soymilk Product and the Structure-Activity Relationship of Synthetic Analogues as Inhibitors of Breast Cancer Cell Growth, Journal of agricultural and food chemistry, vol. 63(44), 9715-9721, 2015任職中研院著作;
|
| 2015 |
Y.-L. Huang, F.-S. Pai, Y.-T. Tsou, H.-C. Mon, T.-L. Hsu, C.-Y. Wu, T.-Y. Chou, W.-B. Yang, C.-H. Chen, C.-H. Wong, S.-L. Hsieh, Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity, The Journal of biological chemistry, vol. 290(35), 21252-21263, 2015任職中研院著作;
|
| 2015 |
J.-T. Chen, K.-L. Ku, C.-H. Chen, M. Hsiao, C.-P. Chiang, T.-L. Hsu, M.-H. Chen, C.-H. Wong, Glycoprotein B7-H3 overexpression and aberrant glycosylation in oral cancer and immune response, Proceedings of the National Academy of Sciences of the United States of America, vol. 112(42), 13057-13062, 2015任職中研院著作;
|
| 2015 |
T.-W. Lin, H.-T. Chang, C.-H. Chen, C.-H. Chen, S.-W. Lin, T.-L. Hsu, C.-H. Wong, Galectin-3 Binding Protein and Galectin-1 Interaction in Breast Cancer Cell Aggregation and Metastasis, Journal of the American Chemical Society, vol. 137(30), 9685-9693, 2015任職中研院著作;
|
| 2015 |
H.-Y. Yen, Y.-C. Liu, N.-Y. Chen, C.-F. Tsai, Y.-T. Wang, Y.-J. Chen, T.-L. Hsu, P.-C.Yang, C.-H. Wong, Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition, Proceedings of the National Academy of Sciences of the United States of America, vol. 112(22), 6955-6960, 2015任職中研院著作;
|
| 2015 |
S. Danishefsky, Y.-K. Shue, M. Chang, C.-H. Wong, Development of Globo-H Cancer Vaccine, Accounts of Chemical Research, vol. 48 (3), 643-652, 2015任職中研院著作;
|
| 2015 |
X. Li, A. Kawamura, C. Andrews, J. Miller, D. Wu; M. Zhang, J. Huang, D. Oren, N. Padte, S. Porcelli, C.-H. Wong, S. Kappe, D. Ho, M. Tsuji, Co-localization of a CD1d-binding glycolipid with malaria vaccines in LN-resident DCs for a robust adjuvant effect, JOURNAL OF IMMUNOLOGY, vol. 195(6), 2710-2721, 2015任職中研院著作;
|
| 2015 |
C.-H. Wong, Chemistry in Taiwan and Academia Sinica, Angewandte Chemie-International Edition, vol. 54(46), 13472-13473, 2015任職中研院著作;
|
| 2015 |
C.-W. Lin, M.-H. Tsai, S.-T. Li, T.-I. Tsai, K.-C. Chu, Y.-C. Liu, M.-Y. Lai, C.-Y. Wu, Y.-C. Tseng, S. S. Shivatare, C.-H. Wang, P. Chao, S.-Y. Wang, H.-W. Shih, Y.-F. Zeng, T.-H. You, J.-Y. Liao, Y.-C. Tu, Y.-S. Lin, H.-Y. Chuang, C.-L. Chen, C.-S. Tsai, C.-C. Huang, N.-H. Lin, C. Ma, C.-Y. Wu, C.-H. Wong, A common glycan structure on immunoglobulin G for enhancement of effector functions, Proceedings of the National Academy of Sciences of the United States of America, vol. 112(34), 10611-10616, 2015任職中研院著作;
|
| 2014 |
J.-R. Chen, Y.-H. Yu, Y.-C. Tseng, W.-L. Chiang, M.-F. Chiang, Y.-A. Ko, Y.-K. Chiu, S.-H. Ma, C.-Y. Wu, J.-T. Jan, K.-I. Lin, C. Ma, C.-H. Wong, Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections, Proceedings of the National Academy of Sciences of the United States of America, vol. 111 (7), 2476-2481, 2014任職中研院著作;
|
| 2014 |
J. Lin, Y.-J. Chang, W.-B. Yang, A. L. Yu, C.-H. Wong, The Multifaceted Effects of Polysaccharides Isolated from Dendrobium huoshanense on Immune Functions with the Induction of Interleukin-1 Receptor Antagonist (IL-1ra) in Monocytes., PloS one, vol. 9(4), e94040, 2014任職中研院著作;
|
| 2014 |
C.-L. Chen, T.-C. Lin, S.-Y. Wang, J.-J. Shie, K.-C. Tsai, Y.-S. E. Cheng, J.-T. Jan, C.-J. Lin, J.-M. Fang, C.-H. Wong, Tamiphosphor Monoesters as Effective Anti-influenza Agents, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 81, 106-118, 2014任職中研院著作;
|
| 2014 |
Y.-W. Lou, P.-Y. Wang, S.-C. Yeh, P.-K. Chuang, S.-T. Li, C.-Y. Wu, K.-H. Khoo, M. Hsiao, T.-L. Hsu, C.-H. Wong, Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers, Proceedings of the National Academy of Sciences of the United States of America, vol. 111 (7), 2482-2487, 2014任職中研院著作;
|
| 2014 |
C.-Y. Wang, C.-Y. Wu, T.-J. Hung, C.-H. Wong, C.-H. Chen, Sequence-constructive SELEX: A new strategy for screening DNA aptamer binding to Globo H., Biochemical and biophysical research communications, vol. 452(3), 484-489, 2014任職中研院著作;
|
| 2014 |
P.-C. Chen, P.-K. Chuang, C.-H. Chen, J.-R. Chen, S.-W. Lin, C. Ma, T.-L. Hsu, C.-H. Wong, Role of N-linked glycans in the interactions of recombinant HCV envelope glycoproteins with cellular receptors., ACS chemical biology, vol. 9(7), 1437-1443, 2014任職中研院著作;
|
| 2014 |
J.-T. Hung, Y.-C. Tsai, W.-D. Lin, J.-T. Jan, K.-H. Lin, J.-R. Huang, J.-Y. Cheng, M.-W. Chen, C.-H. Wong, A. L. Yu, Potent adjuvant effects of novel NKT stimulatory glycolipids on hemagglutinin based DNA vaccine for H5N1 influenza virus., Antiviral research, vol. 107, 110-118, 2014任職中研院著作;
|
| 2014 |
B.-T. Hong, C.-L. Chen, Jim-Min Fang, Shi-Yun Wang, Wen-I Huang, Yih-Shyun E. Cheng, Chi-Huey Wong, Oseltamivir Hydroxamate and Acyl Sulfonamide Derivatives as Influenza Neuraminidase Inhibitors, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22(23), 6647-6654, 2014任職中研院著作;
|
| 2014 |
C.-S. Chu, P.-W. Lo, Y.-H. Yeh, P.-H. Hsu, S.-H. Peng, Y.-C. Teng, M.-L. Kang, C.-H. Wong, L.-J. Juan, O-GlcNAcylation regulates EZH2 protein stability and function., Proceedings of the National Academy of Sciences of the United States of America, vol. 111(4), 1355-1360, 2014任職中研院著作;
|
| 2014 |
H.-Y. Lee, C.-Y. Chen, T.-I. Tsai, S.-T. Li, K.-H. Lin, Y.-Y. Cheng, C.-T. Ren, T.-J. Cheng, C.-Y. Wu, C.-H. Wong, Immunogenicity study of Globo H derivatives with modification at the reducing or non-reducing end of the tumor antigen, J. Am. Chem. Soc., vol. 136(48), 16844-16853, 2014任職中研院著作;
|
| 2014 |
C.-H. Hsu, M. Schelwies, S. Enck, L.-Y. Huang, S.-H. Huang, Y.-F. Chang, T.-J. Cheng, W.-C. Cheng, C.-H. Wong, Iminosugar C-Glycoside Analogues of alpha-d-GlcNAc-1-Phosphate: Synthesis and Bacterial Transglycosylase Inhibition., The Journal of organic chemistry, vol. 79(18), 8629-8637, 2014任職中研院著作;
|
| 2014 |
S.-C. Lin, W.-C. Liu, J.-T. Jan, C.-H. Wong, S.-C. Wu, Glycan Masking of Hemagglutinin for Adenovirus Vector and Recombinant Protein Immunizations Elicits Broadly Neutralizing Antibodies against H5N1 Avian Influenza Viruses, PLoS One, vol. 9(3), e92822, 2014任職中研院著作;
|
| 2014 |
L.-Y. Huang, S.-H. Huang, Y.-C. Chang, W.-C. Cheng, T.-J. R. Cheng, C.-H. Wong, Enzymatic Synthesis of Lipid II and Analogues., Angewandte Chemie-International Edition, vol. 53(31), 8060-8065, 2014任職中研院著作;
|
| 2014 |
Y.-Y. Tseng, J.-M. Liou, T.-L. Hsu, W.-C. Cheng, M.-S. Wu, C.-H. Wong, Development of bacterial transglycosylase inhibitors as new antibiotics: Moenomycin A treatment for drug-resistant Helicobacter pylori., Bioorganic & medicinal chemistry letters, vol. 24(11), 2412-2414, 2014任職中研院著作;
|
| 2014 |
J.-M. Fang, Y.-S. Chen, H.-M. Yu, J.-J. Shie, T.-J. R. Cheng, C.-Y. Wu, C.-H. Wong, Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity., Bioorganic & medicinal chemistry, vol. 22(5), 1766-1772, 2014任職中研院著作;
|
| 2014 |
A.-K. Sauer, C.-H. Liang, J. Stech, B. Peeters, P. Quéré, C. Schwegmann-Wessels, C.-Y. Wu, C.-H. Wong, G. Herrler, Characterization of the sialic Acid binding activity of influenza a viruses using soluble variants of the h7 and h9 hemagglutinins., PloS one, vol. 9(2), e89529, 2014任職中研院著作;
|
| 2014 |
E. Falkowska, A. Ramos, K. J. Doores, J. H. Lee, C. Blattner, A. Ramirez, R. Derking, M. J. van Gils, C.-H. Liang, R. Mcbride, S. S. Shivatare, C.-Y. Wu, P.-Y. Chan-Hui, Y. Liu, T. Feizi, M. B. Zwick, W. C. Koff, M. S. Seaman, K. Swiderek, J. P. Moore, J. C. Paulson, C.-H. Wong, A. B. Ward, I. A. Wilson, R. W. Sanders, P. Poignard, D. R. Burton, Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers., Immunity, vol. 40(5), 657-668, 2014任職中研院著作;
|
| 2014 |
J.-J. Shie, Y.-C. Liu, Y.−M. Lee, C. Lim, J.-M. Fang, C.-H. Wong, An azido-BODIPY probe for glycosylation: initiation of strong fluorescence upon triazole formation, Journal of the American Chemical Society, vol. 136 (28), 9953-9961, 2014任職中研院著作;
|
| 2014 |
J -R. Huang, Y.-C. Tsia, Y.-J. Chang, J.-C. Wu, J.-T. Hung, K.-H. Lin, C.-H. Wong, Alice L. Yu, alpha-Galactosylceramide but Not Phenyl-Glycolipids Induced NKT Cell Anergy and IL-33-Mediated Myeloid-Derived Suppressor Cell Accumulation via Upregulation of egr2/3., Journal of immunology, vol. 192(4), 1972-1981, 2014任職中研院著作;
|
| 2013 |
T.-L. Hsu, G. Lin, A. Koizumi, K. Brehm, N. Hada, P.-K.Chuang, C.-H. Wong, S.-L. Hsieh, A. Diaz, The surface carbohydrates of the Echinococcus granulosus larva interact selectively with the rodent Kupffer cell receptor., Molecular and biochemical parasitology, vol. 192(1-2), 55-9, 2013任職中研院著作;
|
| 2013 |
C.-C.Tsai, C.-R. Lin, H.-Y. Tsai, C.-J. Chen, W.-T. Li, H.-M.Yu, Y.-Y. Ke, W.-Y. Hsieh, C.-Y. Chang, C.-Y. Wu, S.-T. Chen, C.-H. Wong, The Immunologically Active Oligosaccharides Isolated from Wheatgrass Modulate Monocytes via Toll-like Receptor-2 Signaling., The Journal of biological chemistry, vol. 288(24), 17689-17697, 2013任職中研院著作;
|
| 2013 |
C.-H. Wang, S.-T. Li, T.-L. Lin, Y.-Y. Cheng, T.-H. Sun, J.-T. Wang, T.-J. Cheng, K.-K. Mong, C.-H. Wong, C.-Y. Wu, Synthesis of Neisseria meningitidis Serogroup W135 Capsular Oligosaccharides for Immunogenicity Comparison and Vaccine Development., ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 52(35), 9157-9161, 2013任職中研院著作;
|
| 2013 |
H.-Y.Chuang, C.-T. Ren, C.-A. Chao, C.-Y. Wu, S. Shivatare; T.-J. R. Cheng, C.-Y. Wu, C.-H. Wong, Synthesis and Vaccine Evaluation of the Tumor-Associated Carbohydrate Antigen RM2 from Prostate Cancer., Journal of the American Chemical Society, vol. 135(30), 11140-11150, 2013任職中研院著作;
|
| 2013 |
K. Ohara, C.-C. Lin, P.-J. Yang, W.-T. Hung, W.-B. Yang, T.-J. Cheng, J.-M. Fang, C.-H. Wong, Synthesis and Bioactivity of beta-(1-->4)-Linked Oligomannoses and Partially Acetylated Derivatives., The Journal of organic chemistry, vol. 78(13), 6390-6411, 2013任職中研院著作;
|
| 2013 |
W. Chen, S. Enck, J. Price, D. Powers, E. Powers, C.-H. Wong, H. J. Dyson, J. Kelly, Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins., Journal of the American Chemical Society, vol. 135(26), 9877-9884, 2013任職中研院著作;
|
| 2013 |
K.-T. Chen, Y.-C. Kuan, W.-C. Fu, H.-W. Shih, P.-H. Liang, T.-J. R. Cheng, C.-H. Wong, W.-C. Cheng, Rapid Preparation of Mycobacterium N-Glycolyl Lipid I and Lipid II Derivatives via a Biocatalytic Approach, Chemistry a European Journal, vol. 19(3), 834-838, 2013任職中研院著作;
|
| 2013 |
S.-H. Huang, W.-S. Wu, L.-Y., Huang, W.-F., Huang, W.-C., Fu, ; S.-T. Yang, P.-T. Chen, J.-M. Fang, W.-C. Cheng, T.-J. Cheng, C.-H. Wong, New continuous fluorometric assay for bacterial transglycosylase using forster resonance energy transfer., Journal of the American Chemical Society, vol. 135(45), 17078-17089, 2013任職中研院著作;
|
| 2013 |
R. Bryk, N. Arango, C. Maksymiuk, A. Balakrishnan, Y.-T. Wu, C.-H. Wong, T. Masquelin, P. Hipskind, C. D. Lima, C. Nathan, Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase, BIOCHEMISTRY, vol. 52(51), 9375-9384, 2013任職中研院著作;
|
| 2013 |
T.-C. Hung, C.-W. Lin, T.-L. Hsu, C.-Y. Wu, C.-H. Wong, Investigation of SSEA-4 binding protein in breast cancer cells., Journal of the American Chemical Society, vol. 135(16), 5934-5937, 2013任職中研院著作;
|
| 2013 |
S.-F. Liao, C.-H. Liang, M.-Y. Ho, T.-L. Hsu, T.-I. Tsai, Y. S.-Y. Hsieh, S.-T. Li, Y.-Y. Cheng, S.-M. Tsao, T.-Y. Lin, Z.-Y. Lin, W.-B. Yang, C.-T. Ren, K.-I. Lin, K.-K. Khoo, C.-H. Lin, H.-Y. Hsu, C.-Y. Wu, C.-H. Wong, Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies against tumor-associated Globo H-series epitopes, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 110, 13809-13814, 2013任職中研院著作;
|
| 2013 |
C.-Y. Chen, Y.-H. Jan, Y.-H. Juan, C.-J. Yang, M.-S. Huang, C.-J. Yu, P.-C. Yang, M. Hsiao, T.-L. Hsu, C.-H. Wong, Fucosyltransferase 8 as a Functional Regulator of Non-Small Cell Lung Cancer, Proceedings of the National Academy of Sciences of the United States of America, vol. 110 (2), 630-635, 2013任職中研院著作;
|
| 2013 |
S. Shivatare, S.-H.Chang, T.-I. Tsai, C.-T. Ren, H.-Y. Chuang, L. Hsu, C.-W. Lin, S.-T. Li, C.-Y. Wu, C.-H. Wong, Efficient Convergent Synthesis of Bi-, Tri-, and Tetra-antennary Complex Type N-Glycans and Their HIV-1 Antigenicity., Journal of the American Chemical Society, vol. 135(41), 15382-15391, 2013任職中研院著作;
|
| 2013 |
T.-I. Tsai, H.-Y. Lee, S.-H. Chang, C.-H. Wang, Y.-C. Tu, Y.-C. Lin, D.-R. Hwang, C.-Y. Wu, C.-H. Wong, Effective sugar nucleotide regeneration for the large-scale enzymatic synthesis of Globo H and SSEA4., Journal of the American Chemical Society, vol. 135(39), 14831-14839, 2013任職中研院著作;
|
| 2013 |
S.-C. Lin, J.-T. Jan, B. Dionne, M. Butler, M.-H. Huang, C.-Y. Wu, C.-H. Wong, S.-C. Wu, Different Immunity Elicited by Recombinant H5N1 Hemagglutinin Proteins Containing Pauci-Mannose, High-Mannose, or Complex Type N-Glycans., PloS one, vol. 8(6), e66719, 2013任職中研院著作;
|
| 2013 |
C.-Y. Yang, J.-B. Chen, T.-F. Tsai, Y.-C. Tsai, C.-Y. Tsai, P.-H. Liang, T.-L. Hsu, C.-Y. Wu, M. G. Netea, C.-H. Wong, S.-L. Hsieh, CLEC4F Is an Inducible C-Type Lectin in F4/80-Positive Cells and Is Involved in Alpha-Galactosylceramide Presentation in Liver., PloS one, vol. 8(6), e65070, 2013任職中研院著作;
|
| 2013 |
T.-J. R. Cheng, S.-Y. Wang, W.-H. Wen, C.-Y. Su, M. Lin, W.-I. Huang, M.-T. Liu, H.-S. Wu, N-S. Wang, C.-K. Cheng, C.-L. Chen, C.-T. Ren, C.-Y. Wu, J.-M. Fang, Y.-S. E. Cheng, C.-H. Wong, Chemical probes for drug resistance assessment by binding competition (RABC) oseltamivir susceptibility evaluation, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 52(1), 366-370, 2013任職中研院著作;
|
| 2013 |
Y.-L. Huang, J.-T. Hung, S. K.C. Cheung, H.-Y. Lee, K.-C. Chu, S.-T. Li, Y.-C. Lin, C.-T. Ren, T.-J. R. Cheng, T.-L. Hsu, A. L. Yu, C.-Y. Wu, C.-H. Wong, Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer, Proceedings of the National Academy of Sciences of the United States of America, vol. 110 (7), 2517-2522, 2013任職中研院著作;
|
| 2013 |
H.-W. Huang, C.-H. Chen, C.-H. Lin, C.-H. Wong, K.-I. Lin, B-cell maturation antigen is modified by a single N-glycan chain that modulates ligand binding and surface retention., Proceedings of the National Academy of Sciences of the United States of America, vol. 110(27), 10928-10933, 2013任職中研院著作;
|
| 2013 |
N. Padte, M. B. Carrera, C. A. McManus, B. Grasperge, A. Gettie, J. Coelho-dos-Reis, X. Li, N. Levenkova, D. Wu, J. T. Bruder, M. Sedegah, N. Petterson, T. Richie, C.-H. Wong, D. D. Ho, S. Vasan, M. Tsuji, A Glycolipid Adjuvant, 7DW8-5, Enhances CD8+ T Cell Responses Induced by an Adenovirus-Vectored Malaria Vaccine in Non-Human Primates., PloS one, vol. 8(10), e78407, 2013任職中研院著作;
|
| 2013 |
C.-S. Tsai, H.-Y. Yen, M.-I. Lin, T.-I. Tsai, S.-Y. Wang, W.-I. Huang, T.-L. Hsu, Y.-S. E. Cheng, J.-M. Fang, C.-H. Wong, A Cell Permeable Probe for Identification and Imaging of Sialidases, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 110(7), 2466-2471, 2013任職中研院著作;
|
| 2013 |
E. Al-Shareffi, J.-L. Chaubard, C. Leonhard-Melief, C.-H. Wong, R. S. Haltiwanger, 6-Alkynyl Fucose is a bioorthogonal analogue for O-fucosylation of Epidermal Growth Factor-like repeats and Thrombospondin Type-1 repeats by Protein O-Fucosyltransferases 1 and 2., Glycobiology, vol. 23(2), 188-198, 2013任職中研院著作;
|
| 2013 |
K. J. Doores, M. Huber, K. M. Le, S.-K. Wang, C. Doyle-Cooper, A. Cooper, R. Pantophlet, C.-H. Wong, D. Nemazee, D. R. Burton, 2G12-expressing B cell lines inform HIV carbohydrate vaccine design strategies, Journal of Virology, vol. 87(4),2234-2241, 2013任職中研院著作;
|
| 2012 |
S.-C. Hung, M. Zulueta, S.-Y. Lin, Y.-T. Lin, C.-J. Huang, C.-C. Wang, C.-C. Ku, Z.-H. Shi, C.-L. Chyan, D. Irene, L.-H. Lim, T.-I. Tsai, Y.-P. Hu, S. Arco, C.-H. Wong, α-Glycosylation by D-Glucosamine-Derived Donors: Synthesis of Heparosan and Heparin Analogs that Interact with Mycobacterial Heparin-Binding Hemagglutinin, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 134 (21), 8988-8995, 2012任職中研院著作;
|
| 2012 |
M.-H. Hsieh, J.-T. Hung, Y.-W. Liw, Y.-J. Lu, C.-H. Wong, A. L. Yu, P.-H. Liang, Synthesis and evaluation of acyl-chain- and galactose-6''-modified analogues of alpha-GalCer for NKT cell activation., Chembiochem, vol. 13(11), 1689-1697, 2012任職中研院著作;
|
| 2012 |
J. L. Price, E. K. Culyba, W. Chen, A. N. Murray, S. R. Hanson, C.-H. Wong, E. T. Powers, J. W. Kelly, N-glycosylation of enhanced aromatic sequons to increase glycoprotein stability., Biopolymers, vol. 98(3), 195-211, 2012任職中研院著作;
|
| 2012 |
J. Lenger, M. Schröder, E. C. Ennemann, B. Müller, C.-H. Wong, T. Noll, T. Dierks, S. R. Hanson, N. Sewald, Evaluation of Sulfatase-Directed Quinone Methide Traps for Proteomics, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 20(2), 622-627, 2012任職中研院著作;
|
| 2012 |
K.-C. Liu, J.-M. Fang, J.-T. Jan, T.-J. R. Cheng, S.-Y. Wang, Y.-S. E. Cheng, K.-C. Tsai, A.-S. Yang, C.-H. Wong, Enhanced Anti-influenza Agents Conjugated with Anti-inflammatory Activity., Journal of medicinal chemistry, vol. 55(19), 8493-8501, 2012任職中研院著作;
|
| 2012 |
S.-H. Chen, D.-R. Hwang, G.-H. Chen, N.-S. Hsu, Y.-T. Wu, T.-L. Li, C.-H. Wong, Engineering Transaldolase in Pichia stipitis to Improve Bioethanol Production, ACS CHEMICAL BIOLOGY, vol. 7(3), 481-486, 2012任職中研院著作;
|
| 2012 |
H.-W. Shih, Y.-F. Chang, W.-J. Li, F.-C. Meng, C.-Y. Huang, C. Ma, T.-J. R. Cheng, C.-H. Wong, W.-C. Cheng, Effect of the peptide moiety of lipid II on bacterial transglycosylase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 51(40), 10123-10126, 2012任職中研院著作;
|
| 2012 |
T.-J. R. Cheng, S. Weinheimer, E. B. Tarbet, J.-T. Jan, Y.-S. E. Cheng, J.-J. Shie, C.-L. Chen, C.-A. Chen, W.-C. Hsieh, P.-W. Huang, W.-H. Lin, S.-Y. Wang, J.-M. Fang, O. Y.-P. Hu, C.-H. Wong, Development of Oseltamivir Phosphonate Congeners as Anti-influenza Agents., Journal of medicinal chemistry, vol. 55(20), 8657-8670, 2012任職中研院著作;
|
| 2012 |
C.-Y. Huang, H.-W. Shih, L-Y. Lin, Y.-W. Tien, T.-J. R. Cheng, W.-C. Cheng, C.-H. Wong, C. Ma, Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with a lipid II analog and elucidation of the mechanism of peptidoglycan synthesis, Proceedings of the National Academy of Sciences of the United States of America, vol. 109 (7), 6496-6501, 2012任職中研院著作;
|
| 2012 |
Y. Hsu, X.-A. Lu, M. Zulueta, C.-M. Tsai, K.-I. Lin, S.-C. Hung, C.-H. Wong, Acyl and Silyl Group Effects in Reactivity-based One-pot Glycosylation: Synthesis of Embryonic Stem Cell Surface Carbohydrates Lc4 and IV2Fuc-Lc4 , JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 134(10), 4549-4552, 2012任職中研院著作;
|
| 2011 |
C.-H. Hsu, S.-C. Hung, C.-Y. Wu, C.-H. Wong, Toward Automated Oligosaccharide Synthesis, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 50 (50), 11872-11923, 2011任職中研院著作;
|
| 2011 |
F.-C. Meng, K.-T. Chen, L.-Y. Huang, H.-W. Shih, H.-H. Chang, F.-Y. Nien, P.-H. Liang, T.-J. Cheng, C.-H. Wong, W.-C. Cheng, Total Synthesis of Polyprenyl N-Glycolyl Lipid II as a Mycobacterial Transglycosylase Substrate, ORGANIC LETTERS, vol. 13(19), 5306-5309, 2011任職中研院著作;
|
| 2011 |
R. T. Lee, T.-L. Hsu, S. K. Huang, S.-L. Hsieh, C.-H. Wong, Y. C. Lee, Survey of immune-related, mannose/fucose-binding C-type lectin receptors reveals widely divergent sugar-binding specificities, GLYCOBIOLOGY, vol. 21(4), 512-520, 2011任職中研院著作;
|
| 2011 |
C.-F. Chang, J.-F. Pan, C.-N. Lin, C.-H. Wong, C.-H. Lin, Rapid Characterization of Sugar-Binding Specificity by In-Solution Proximity Binding with Photosensitizers, GLYCOBIOLOGY, vol. 21(7), 895-902, 2011任職中研院著作;
|
| 2011 |
E. K. Culyba, J. L. Price, S. R. Hanson, A. Dhar, C.‐H. Wong, M. Gruebele, E. T. Powers, J. W. Kelly, Protein native-state stabilization by placing aromatic side chains in N-glycosylated reverse turns, Science, vol. 331(6017), 571-575, 2011任職中研院著作;
|
| 2011 |
C.-Y. Wu, C.-H. Wong, Programmable one-pot glycosylation, Topics in Current Chemistry, vol. 301, 223-252, 2011任職中研院著作;
|
| 2011 |
C.-Y. Chou, T.-P. Ko, K.-J. Wu, K.-F. Huang, C.-H. Lin, C.-H. Wong, A. H.-J. Wang, Modulation of Substrate Specificities of D-Sialic Acid Aldolase through Single Mutations of Val-251., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 286(16), 14057-14064, 2011任職中研院著作;
|
| 2011 |
Y. Kinjo, P. Illarionov, J. L. Vela, B. Pei, E. Girardi, X. Li, Y. Li, M. Imamura, Y. Kaneko, Y. Miyazaki, P. Rogers, S. Dahesh, S. Uchiyama, A. Khurana, K. Kawahara, H. Yesilkaya, P. W. Andrew, C.-H. Wong, K. Kawakami, V. Nizet, G. S. Besra, M. Tsuji, D. M. Zajonc, M. Kronenberg, Invariant NKT cells recognize glycolipids from pathogenic Gram-positive bacteria, NATURE IMMUNOLOGY, vol. 12(10), 966-974, 2011任職中研院著作;
|
| 2011 |
D. Punyadarsaniya, C.-H. Liang, C. Winter, H. Petersen, S. Rautenschlein, I. Hennig-Pauka, C. Schwegmann-Wessels, C.-Y. Wu, C.-H. Wong, G. Herrler, Infection of differentiated porcine airway epithelial cells by influenza virus: differential susceptibility to infection by porcine and avian viruses, PLoS One, vol. 6(12), e28429, 2011任職中研院著作;
|
| 2011 |
J.-W. Hsu, H.-C. Huang, S.-T. Chen, C.-H. Wong, H.-F. Juan, Ganoderma lucidum polysaccharides induce macrophage-like differentiation in human leukemia THP-1 cells via caspase and p53 activation, EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, vol. 1-13, 2011任職中研院著作;
|
| 2011 |
C.-H. Liang, S.-K. Wang, C.-W. Lin, C.-C. Wang, C.-H. Wong, C.-Y. Wu, Effects of neighboring glycans on antibody-carbohydrate interaction, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 50(7), 1608-1612, 2011任職中研院著作;
|
| 2011 |
Y.-F. Shen, Y.-H. Chen, S.-Y. Chu, M.-I. Lin, H.-T. Hsu, P.-Y. Wu, C.-J. Wu, H.-W. Liu, F.-Y. Lin, G. Lin, P.-H. Hsu, A.-S. Yang, Y.-S. E. Cheng, Y.-T. Wu, C.-H. Wong, M.-D. Tsai, E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors, Proceedings of the National Academy of Sciences of the United States of America, vol. 108(40), 16515-16520, 2011任職中研院著作;
|
| 2011 |
C.-Y. Wu, C.-H. Wong, Chemistry and glycobiology, CHEMICAL COMMUNICATIONS, vol. 47(22), 6201-6207, 2011任職中研院著作;
|
| 2011 |
M. W. Chen, H.-Y. Liao, T.-J. R. Cheng, C.-T. Ren, C.-Y. Wu, Y. Huang, D. D. Ho, C.-H. Wong, Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 108(9), 3510-3515, 2011任職中研院著作;
|
| 2011 |
T.-N. Wu, K.-H. Lin, Y.-J. Chang, J.-R. Huang, J.-Y. Cheng, A. L. Yu, C.-H. Wong, Avidity of CD1d-ligand-receptor ternary complex contributes to Th1 polarization and anticancer efficacy, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 108(42), 17275-17280, 2011任職中研院著作;
|
| 2011 |
J.-J. Shie, J.-M. Fang, P.-T. Lai, W.-H. Wen, S.-Y. Wang, Y.-S. Cheng, K.-C. Tsai, A.-S. Yang, C.-H. Wong, A Practical Synthesis of Zanamivir Phosphonate Congeners with Potent Anti-influenza Activity, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 133(44), 17959-17965, 2011任職中研院著作;
|
| 2011 |
R. Pejchal, K.J. Doores, L.M. Walker, R. Khayat, P.-S. Huang, S.-K. Wang, R.L. Stanfield, J.P. Julien, A. Ramos, M. Crispin, R. Depetris, U. Katpally, A. Marozsan, A. Cupo, S. Maloveste, Y. Liu, R. McBride, Y. Ito, R.W. Sanders, C. Ogohara, J.C. Paulson, T. Feizi, C.N. Scanlan, C.-H. Wong, J.P. Moore, W.C. Olson, A.B. Ward, P. Poignard, W.R. Schief, D.R. Burton, I.A. Wilson, A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield, SCIENCE, vol. 334(6059), 1097-1103, 2011任職中研院著作;
|
| 2011 |
H.-W. Shih, K.-T. Chen, T.-J. Cheng, C.-H. Wong, W.-C. Cheng, A New Synthetic Approach toward Bacterial Transglycosylase Substrates, Lipid II and Lipid IV, ORGANIC LETTERS, vol. 13(17), 4600-4603, 2011任職中研院著作;
|
| 2011 |
B.-L. Tsai, J.-L. Han, C.-T. Ren, C.-Y. Wu, C.-H. Wong, Programmable One-Pot Synthesis of Tumor-Associated Carbohydrate Antigens Lewis X Dimer and KH-1 Epitopes, TETRAHEDRON LETTERS, vol. 52(17), 2132-2135, 2011任職中研院著作;
|
| 2011 |
J.-R. Chen, C. Ma, C.-H. Wong, Vaccine design of hemagglutinin glycoprotein against influenza, TRENDS IN BIOTECHNOLOGY, vol. 29(9), 426-434, 2011任職中研院著作;
|
| 2011 |
Y.-C. Liu, H.-Y. Yen, C.-Y. Chen, C.-H. Chen, P.-F. Cheng, Y.-H. Juan, C.-H. Chen, K.-H. Khoo, C.-J. Yu, P.-C. Yang, T.-L. Hsu, C.-H. Wong, Sialylation and Fucosylation of Epidermal Growth Factor Receptor Suppress its Dimerization and Activation in Lung Cancer Cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 108 (28), 11332-11337, 2011任職中研院著作;
|
| 2011 |
R. Schmaltz, S. R. Hanson, C.-H. Wong, Enzymes in the Synthesis of Glycoconjugates, CHEMICAL REVIEWS, vol. 111(7), 4259-4307, 2011任職中研院著作;
|
| 2011 |
K.-C. Liu, P.-S. Lee, S.-Y. Wang, Y.-S. E. Cheng, J.-M. Fang, C.-H. Wong, Intramolecular ion-pair prodrugs of zanamivir and guanidino-oseltamivir, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19(16), 4796-4802, 2011任職中研院著作;
|
| 2011 |
H.-L. Yen, C.-H. Liang, C.-Y. Wu, H. Forrest, A. Ferguson, K.T. Choy, J. Jones, D.D.Y. Wong, P.P.H. Cheung, C.-H. Hsu, O.T. Li, K.M. Yuen, R.W.Y. Chan, L.L.M. Poon, M.C.W. Chan, J. Nicholls, S. Krauss, C.-H. Wong, Y. Guan, R.G. Webster, R.J. Webby & J.S.M. Peiris, Hemagglutinin-neuraminidase balance confers respiratory droplet transmissibility of the pandemic H1N1 influenza virus in ferrets, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 108(34), 14264-14269, 2011任職中研院著作;
|
| 2011 |
K.-C. Chu, C.-T. Ren, C.-P. Lu, C.-H. Hsu, T.-H. Sun, T.-A. Chao, Y.-F. Lin, S.-H. Wu, C.-H. Wong, C.-Y. Wu, Efficient and Stereoselective Synthesis of α(2→9) Oligosialic Acids Up to Dodecamer, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 50(40), 9391-9395, 2011任職中研院著作;
|
| 2011 |
L. M. Walker, M. Huber, K. J. Doores, E. Falkowska, R. Pejchal, J.-P. Julien, S.-K. Wang, P.-Y. Chan-Hui, P. W. Hammond, O. A. Olsen, A. Ramos, P. Phung, T. Wrin, M. D. Simek, S. Fling, C.-H. Wong, S. Phogat, W. C. Koff, I. A. Wilson, D. R. Burton, P. Poignard, Broad neutralization coverage of HIV by multiple highly potent antibodies, NATURE, vol. 477(7365), 466-470, 2011任職中研院著作;
|
| 2010 |
C.-Y. Liu, C.-W. Guo, Y.-F. Chang, J.-T. Wang, H.-W. Shih, Y.-F. Hsu, C.-W. Chen, S.-K. Chen, Y.-C. Wang, T.-J. Cheng, C. Ma, C.-H. Wong, J.-M. Fang, W.-C. Cheng, Synthesis and evaluation of a new fluorescent transglycosylase substrate: lipid II-based molecule possessing a dansyl-C20 polyprenyl moiety., Organic letters, vol. 12(7), 1608-1611, 2010任職中研院著作;
|
| 2010 |
J.-J. Shie, C.-A. Chen, C.-C. Lin, A. F. Ku, T.-J. R. Cheng, J.-M. Fang, C.-H. Wong, Regioselective synthesis of di-C-glycosylflavones possessing anti-inflammation activities., Organic & biomolecular chemistry, vol. 8(19), 4451-4462, 2010任職中研院著作;
|
| 2010 |
K.-H. Lin, J.-J. Liang, W.-I. Huang, S.-Y. Lin-Chu, C.-Y. Su, Y.-L. Lee, J.-T. Jan, Y.-L. Lin, Y.-S. E. Cheng, C.-H. Wong, In vivo protection of bacterial and viral infections in murine models using a synthetic new {alpha}-GalCer analog., Antimicrobial agents and chemotherapy, vol. 54(10), 4129-4136, 2010任職中研院著作;
|
| 2010 |
C.-H. Hsu, K.-C. Chu, Y.-S. Lin, J.-L. Han, Y.-S. Peng, C.-T. Ren, C.-Y. Wu, C.-H. Wong, Highly alpha-selective sialyl phosphate donors for efficient preparation of natural sialosides., CHEMISTRY-A EUROPEAN JOURNAL, vol. 16(6), 1754-1760, 2010任職中研院著作;
|
| 2010 |
C.-Y. Su, T.-J. R. Cheng, M.-I. Lin, S.-Y. Wang, W.-I. Huang, S.-Y. Lin-Chua, Y.-H. Chen, C.-Y. Wu, M. M. C. Lai, W.-C. Cheng, Y.-T. Wu, M.-D. Tsai, Y.-S. E. Cheng, C.-H. Wong, High-throughput Identification of Compounds Targeting Influenza RNA-dependent RNA Polymerase Activity, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 107(45), 19151-1916, 2010任職中研院著作;
|
| 2010 |
T.-J. R. Cheng, Y.-T. Wu, S.-T. Yang, A. Loh, S.-K. Chen, Y.-H. Chen, W.-I. Huang, C.-H. Yuan, H.-W. Shih, Y.-S. E. Cheng, W.-C. Cheng, C.-H. Wong, High-Throughput Identification of Antibacterials against Methichillin-Resistant Staphylococcus Aureus (MRSA) and the Transglycosylase, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18(24), 8512-8529, 2010任職中研院著作;
|
| 2010 |
S.-H. Chang, J.-L. Han, Susan Y. Tseng, H.-Y. Lee, C.-W. Lin, Y.-C. Lin, W.-Y. Jeng, A. H.-J. Wang, C.-Y. Wu, C.-H. Wong, Glycan Array on Aluminum Oxide Coated Glass Slides Through Phosphonate Chemistry, Journal of the American Chemical Society, vol. 132 (38), 13371-13380, 2010任職中研院著作;
|
| 2010 |
W.-Y. Chen, W.-B. Yang, C.-H. Wong, D.T.-B. Shih, Effect of Reishi Polysaccharides on Human Stem/Progenitor Cells, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18(24), 8583-8591, 2010任職中研院著作;
|
| 2010 |
H.-Y. Liao, C.-H. Hsu, S.-C. Wang, C.-H. Liang, H.-Y. Yen, C.-Y. Su, J.-T. Jan, C.-T. Ren, T.-J. Cheng, C.-Y. Wu, C.-H. Wong, Differential Receptor Binding Affinities of Influenza Hemagglutinins on Glycan Arrays, J. Am. Chem. Soc., vol. 132(42),14849-14856, 2010任職中研院著作;
|
| 2010 |
X. Li, D. Wu, M. Fujio, M. Imamura, S. Vasan, C.-H. Wong, D. D. Ho, M. Tsuji, Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant., Proceedings of the National Academy of Sciences of the United States of America, vol. 107(29), 13010-13015, 2010任職中研院著作;
|
| 2010 |
R. D. Astronomo, E. Kaltgrad, A. K. Udit, S.-K. Wang, R. Pantophlet, C.-Y. Huang, J. C. Paulson, C.-H. Wong, M.G. Finn, D. R. Burton, Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds., Chemistry & biology, vol. 17(4), 357-370, 2010任職中研院著作;
|
| 2010 |
H.-W. Shih, K.-T. Chen, S.-K. Chen, C.-Y. Huang, T.-J. Cheng, C. Ma, C.-H. Wong, W.-C. Cheng, Combinatorial approach toward synthesis of small molecule libraries as bacterial transglycosylase inhibitors., Organic & biomolecular chemistry, vol. 8(11), 2586-2593, 2010任職中研院著作;
|
| 2010 |
J. C. Lewis, S. M. Mantovani, Y. Fu, C. D. Snow, R. S. Komor, C.-H. Wong, F. H. Arnold, Combinatorial Alanine Substitution Enables Rapid Optimization of Cytochrome P450BM3 for Selective Hydroxylation of Large Substrates, CHEMBIOCHEM, vol. 11(18), 2502-2505, 2010任職中研院著作;
|
| 2010 |
W.-H. Wen, S.-Y. Wang, K.-C. Ysai, Y.-S. E. Cheng, A.-S. Yang, J.-M. Fang, C.-H. Wong, Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses., Bioorganic & medicinal chemistry, vol. 18(11), 4074-4084, 2010任職中研院著作;
|
| 2010 |
R. J. Payne, C.-H. Wong, Advances in Chemical Ligation Strategies for the Synthesis of Glycopeptides and Glycoproteins, CHEMICAL COMMUNICATIONS, vol. 46, 21-43, 2010任職中研院著作;
|
| 2010 |
C.-C. Chang, A. F. Ku, Y.-Y. Tseng, W.-B. Yang, J.-M. Fang, C.-H. Wong, 6,8-Di-C-glycosyl flavonoids from Dendrobium huoshanense., Journal of natural products, vol. 73(2), 229-232, 2010任職中研院著作;
|
| 2010 |
S. Otsuki, S. Hanson, S. Miyaki, S. Grogan, M. Kinoshita, H. Asahara, C.-H. Wong, M. Lotz, Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways., Proceedings of the National Academy of Sciences of the United States of America, vol. 107(22), 10202-10207, 2010任職中研院著作;
|
| 2010 |
C.-S. Tsai, P.-Y. Liu, H.-Y. Yen, T.-L. Hsu, C.-H. Wong, Development of trifunctional probes for glycoproteomic analysis., CHEMICAL COMMUNICATIONS, vol. 46(30), 5575-5577, 2010任職中研院著作;
|
| 2010 |
M. Schelwies, D. Brinson, Y.-H. Hong, M. K. Lotz, C.-H. Wong, S. R. Hanson, GlcN-6-sulfamate Heparan Analogs as Inhibitors of Endosulfatases, ChemBioChem, vol. 11(17), 2393-2397, 2010任職中研院著作;
|
| 2009 |
M.-H. Chuang, S.-H. Chiou, C.-H. Huang, W.-B. Yang, C.-H. Wong, The lifespan-promoting effect of acetic acid and Reishi polysaccharide, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17(22), 7831-7840, 2009任職中研院著作;
|
| 2009 |
S. R. Hanson, E. K. Culyba, T. L. Hsu, C.-H. Wong, J. W. Kelly, E. T. Powers, The core trisaccharide of an N-linked glycoprotein intrinsically accelerates folding and enhances stability, Proceedings of the National Academy of Sciences of the United States of America, vol. 106(9), 3131-3136, 2009任職中研院著作;
|
| 2009 |
W.-H. Wen, M. Lin, C.-Y. Su, S.-Y. Wang, Y.-S. E. Cheng, J.-M. Fang, C.-H. Wong, Synergistic effect of zanamivir-porphyrin conjugates on inhibition of neuraminidase and inactivation of influenza virus., Journal of medicinal chemistry, vol. 52(15), 4903-4910, 2009任職中研院著作;
|
| 2009 |
A. Schiefner, M. Fujio, D. Wu, C.-H. Wong, I. A. Wilson, Structural Evaluation of Potent NKT Cell Agonists: Implications for Design of Novel Stimulatory Ligands, JOURNAL OF MOLECULAR BIOLOGY, vol. 394(1), 71-82, 2009任職中研院著作;
|
| 2009 |
C.-Y. Wu, P.-H. Liang, C.-H. Wong, New development of glycan arrays, ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 7(11), 2247-2254, 2009任職中研院著作;
|
| 2009 |
C.-H. Liang, C.-C. Wang, Y.-C. Lin, C.-H. Chen, C.-H. Wong, C.-Y. Wu, Iron Oxide/Gold Core/Shell Nanoparticles for Ultrasensitive Detection of Carbohydrate-Protein Interactions, ANALYTICAL BIOCHEMISTRY, vol. 81(18), 7750-7756, 2009任職中研院著作;
|
| 2009 |
S.-Y. Wang, C.-Y. Su, M. Lin, S.-Y. Huang, W.-I. Huang, C.-C. Wang, Y.-T. Wu, T.-J. R. Cheng, H.-M. Yu, C.-T. Ren, C.-Y. Wu, C.-H. Wong, Y.-S. E. Cheng, HA-pseudotyped retroviral vectors for influenza antagonist screening., Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, vol. 14(3), 294-302, 2009任職中研院著作;
|
| 2009 |
C.-C. Wang, J.-R. Chen, Y.-C. Tseng, C.-H. Hsu, Y.-F. Hung, S.-W. Chen, C.-M. Chen, K.-H. Khoo, T.-J. Cheng, Y.-S. E. Cheng, J.-T. Jan, C.-Y. Wu, C. Ma, C.-H. Wong, Glycans on influenza hemagglutinin affect receptor binding and immune response, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 106(43), 18137-18142, 2009任職中研院著作;
|
| 2009 |
C.-H. Wong, Enzymes for Glycoprotein Synthesis, CHIMIA, vol. 63(6), 318-326, 2009任職中研院著作;
|
| 2009 |
M.-T. Sung, Y.-T. Lai, C.-Y. Huang, L.-Y. Chou, H.-W. Shih, W.-C. Cheng, C.-H. Wong, C. Ma, Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli., Proceedings of the National Academy of Sciences of the United States of America, vol. 106(22), 8824-8829, 2009任職中研院著作;
|
| 2009 |
Z. Hong, L. Liu, M. Sugiyama, Y. Fu, C.-H. Wong, Concise synthesis of iminocyclitols via Petasis-type aminocyclization., Journal of the American Chemical Society, vol. 131(24), 8352-8653, 2009任職中研院著作;
|
| 2009 |
J. C. Lewis, S. Bastian, C. S. Bennett, Y. Fu, Y. Mitsuda, M. M. Chen, W. A. Greenberg, C.-H. Wong, F. H. Arnold, Chemoenzymatic Elaboration of Monosaccharides Using Engineered Cytochrome P450BM3 Demethylases, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 106(39), 16550-16555, 2009任職中研院著作;
|
| 2009 |
L. Motiei, S. Rahimipour, D.A. Thayer, C.-H. Wong, M.R. Ghadiri, Antibacterial cyclic D,L-alpha-glycopeptides., CHEMICAL COMMUNICATIONS, vol. 7(25), 3693-3695, 2009任職中研院著作;
|
| 2009 |
T.-L. Hsu, S.-C. Cheng, W.-B. Yang, S.-W. Chin, S.-L. Hsieh, C.-H. Wong, Profiling Carbohydrate-Receptor Interaction with Recombinant Innate Immunity Receptor-Fc Fusion Proteins, JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 284(50), 34479-34489, 2009任職中研院著作;
|
| 2008 |
S.-K. Wang, P.-H. Liang, R. Astronomo, T.-L. Hsu, S.-L. Hsieh, D. Burton, C.-H. Wong, Tagteting the carbohydrates on HIV-1: interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105(10), 3690-3695, 2008任職中研院著作;
|
| 2008 |
C. Bennett, S. Dean, R. Payne, S. Ficht, A. Brik, C.-H. Wong, Sugar-assisted Glycopeptide Ligation with Complex Oligosaccharides: Scope and Limitations, Journal of the American Chemical Society, vol. 130(36), 11945-11952, 2008任職中研院著作;
|
| 2008 |
Y. S.-Y. Hsieh, C. Chien, S. K.-S. Liao, S.-F. Liao, W.-T. Hung, W.-B. Yang, C.-C. Lin, T.-J. R. Cheng, C.-C. Chang, J.-M. Fang, C.-H. Wong, Structure and Bioactivity of the Polysaccharides in Medicinal Plant Dendrobium huoshanense, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, 6054-6068, 2008任職中研院著作;
|
| 2008 |
S. Ficht, R. Payne, R. Guy, C.-H. Wong, Solid-Phase Synthesis of Peptide- and Glycopeptide Thioesters via Side Chain Anchoring Strategies, CHEMISTRY-A EUROPEAN JOURNAL, vol. 14(12), 3620-3629, 2008任職中研院著作;
|
| 2008 |
P.-H. Liang, M. Imamura, X. Li, D. Wu, M. Fujio, R. Guy, B.-C. Wu, M. Tsuji, C.-H. Wong, Quantitative Microarray Analysis of Intact Glycolipid-CD1d Interaction and Correlation with Cell-based Cytokine Production, J. Am. Chem. Soc, vol. 130(37), 12348-12354, 2008任職中研院著作;
|
| 2008 |
Tupin E, Benhnia MR, Kinjo Y, Patsey R, Lena CJ, Haller MC, Caimano MJ, Imamura M, Wong CH, Crotty S, Radolf JD, Sellati TJ, Kronenberg M, NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi., Proceedings of the National Academy of Sciences of the United States of America, vol. 105(50), 19863-19868, 2008任職中研院著作;
|
| 2008 |
E. Tupin, M. R.-E.-I. Benhnia, Y. Kinjo, R. Patsey, C. Lena, M. Haller, M. J. Caimano, M. Imamura, C.-H. Wong, S. Crotty, J. D. Radolf, T. J. Sellati, M. Kronenberg, NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105(50), 19863-19868, 2008任職中研院著作;
|
| 2008 |
Y. Kinjo, B. Pei, S. Bufali, R. Raju, S. K. Richardson, M. Imamura, M. Fujio, D. Wu, A. Khurana, K. Kawahara, C.-H. Wong, A. R. Howell, P. H. Seeberger, M. Kronenberg, Natural Sphingomonas Glycolipids Vary Greatly in their Ability to Activate Natural Killer T Cells, Chem. Biol, vol. 15(7), 654-664, 2008任職中研院著作;
|
| 2008 |
C.-S. Shi, G.-Y. Shi, S.-M. Hsiao, Y.-C. Kao, K.-L. Kuo, C.-Y. Ma, C.-H. Kuo, B.-I. Chang, C.-F. Chang, C.-H. Lin, C.-H. Wong, H.-L. Wu, Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response, Blood, vol. 112(9), 3661-3670, 2008任職中研院著作;
|
| 2008 |
C.-Y. Su, S.-Y. Wang, J.-J. Shie, K.-S. Jeng, N. J. Temperton, J.-M. Fang, C.-H. Wong, Y.-S.E. Cheng, In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses, ANTIVIRAL RESEARCH, vol. 79(3), 199-205, 2008任職中研院著作;
|
| 2008 |
D. Wu, M. Fujio, C.-H. Wong, Glycolipids as Immunostimulating Agents, Bioorganic & Medicinal Chemistry, vol. 16, 1073-1083, 2008任職中研院著作;
|
| 2008 |
C.-C. Wang, Y.-L. Huang, C.-T. Ren, C.-W. Lin, J.-T. Hung, J.-C. Yu, A. Yu, C.-Y. Wu, C.-H. Wong, Glycan Microarray of Globo H and Related Structures for Quantitative Analysis of Breast Cancer, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105(33), 11661-11666, 2008任職中研院著作;
|
| 2008 |
P-H. Liang, C.-Y. Wu, W. A. Greenberg, C.-H. Wong, Glycan Arrays: Perspectives in Biological and Medical Applications, CURRENT OPINION IN CHEMICAL BIOLOGY, vol. 12(1), 86-92, 2008任職中研院著作;
|
| 2008 |
S. Y. Tseng, C. C. Wang, C.-W. Lin, C.-L. Chen, W.-Y. Yu, C.-H. Chen, C.-Y. Wu, C.-H. Wong, Glycan Arrays on Aluminum Coated Glass Slides, CHEMISTRY-AN ASIAN JOURNAL, vol. 3(8), 1395-1405, 2008任職中研院著作;
|
| 2008 |
Chen ML, Adak AK, Yeh NC, Yang WB, Chuang YJ, Wong CH, Hwang KC, Hwu JR, Hsieh SL, Lin CC, Fabrication of an oriented Fc-fused lectin microarray through boronate formation., ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 47(45), 8627-8630, 2008任職中研院著作;
|
| 2008 |
M.-L. Chen, A.K. Adak, N.-C. Yeh, W.-B. Yang, Y.-J. Chuang, C.-H. Wong, K.-C. Hwang, J.-R.R. Hwu, S.-L. Hsieh, C.-C. Lin, Fabrication of an Oriented Fc-Fused Lectin Microarray through Boronate Formation, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 47(45), 8627-8630, 2008任職中研院著作;
|
| 2008 |
W.-W. Chang, C. H. Lee, P. Lee, J. Lin, C.-W. Hsu, J.-T. Hung, J.-J. Lin, J.-C. Yu, L. Shao, J. Yu, C.-H. Wong, A. Yu, Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 & 2 in Globo H synthesis, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105(33), 11667-11672, 2008任職中研院著作;
|
| 2008 |
T.-J. R. Cheng, M.-D. Sung, H.-Y. Liao, Y.-F. Chang, C.-W. Chen, C.-Y. Huang, L.-Y. Chou, Y.-D. Wu, Y.-H. Chen, Y.-S. E. Cheng, C.-H. Wong, C. Ma, W-C Cheng, Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105(2), 431-436, 2008任職中研院著作;
|
| 2008 |
N.-Y. Hsu, S.Y. Tseng, C.-Y. Wu, C.-T. Ren, Y.-C. Lee, C.-H. Wong, C.-H. Chen, Desorption Ionization of Biomolecules on Metals, ANALYTICAL CHEMISTRY, vol. 80, 5203-5210, 2008任職中研院著作;
|
| 2008 |
Y.-M. Shao, W.-B. Yang, T.-H. Kuo, K.-C. Tsai, C.-H. Lin, A.-S. Yang, P.-H. Liang, C.-H. Wong, Design, Synthesis, and Evaluation of Trifluoromethyl Ketones as Inhibitors of SARS-CoV 3CL Protease, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, 4652-4660, 2008任職中研院著作;
|
| 2008 |
R. Payne, S. Ficht, W. A. Greenberg, C.-H. Wong, Cysteine-Free Peptide and Glycopeptide Ligations by Direct Aminolysis, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 47(23), 4411-4415, 2008任職中研院著作;
|
| 2008 |
S.-T. Chen, Y.-L. Lin, M.-T. Huang, M.-F. Wu, S.-C. Cheng, H.-Y. Lei, C.-K. Lee, T.-W. Chiou, C.-H. Wong, S.-L. Hsieh, CLEC5A is Critical for Dengue Virus-Induced Lethal Disease, Nature, vol. 453, 672-676, 2008任職中研院著作;
|
| 2008 |
T. R. Northen, J.-C. Lee, L. Hoang, J. Raymond, D.-R. Hwang, S.M. Yannone, C.-H. Wong, G. Siuzdak, A Nanostructure-Initiator Mass Spectrometry Based Enzyme Activity Assay, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105(10), 3678-3683, 2008任職中研院著作;
|
| 2008 |
R. D. Astronomo, H. K. Lee, C. N. Scanlan, R. Pantophlet, C. Y. Huang, I. A. Wilson, O. Blixt, R. A. Dwek, C.-H. Wong, D. R. Burton, A glycoconjugate antigen based on the recognition motif of a broadly-neutralising human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120, JOURNAL OF VIROLOGY, vol. 82, 6359-6368, 2008任職中研院著作;
|
| 2008 |
Giffin MJ, Heaslet H, Brik A, Lin YC, Cauvi G, Wong CH, McRee DE, Elder JH, Stout CD, Torbett BE, A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant., Journal of medicinal chemistry, vol. 51(20), 6263-6270, 2008任職中研院著作;
|
| 2008 |
M. J. Giffin, H. Heaslet, A. Brik, Y.-C. Lin, G. Cauvi, C.-H.Wong, D. E. McRee, J. H. Elder, C. D. Stout, B. E. Torbett, A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant, J. Med. Chem, vol. 51(20), 6263-6270, 2008任職中研院著作;
|
| 2008 |
M. W. Chen, T.-J. Cheng, Y. Huang, J.-T. Jan, S.H. Ma, A. Yu, C.-H. Wong, D. Ho, A Consensus-Hemagglutinin-Based DNA Vaccine that Protects Mice Against Divergent H5N1 Influenza Viruses, Proceedings of the national academy of sciences of the united states of america, vol. 105(36), 13538-13543, 2008任職中研院著作;
|
| 2008 |
J.-J. Shie, J.-M. Fang, C.-H. Wong, A Concise and Flexible Synthesis of the Potent Anti-Influenza Agents – Tamiflu and Tamiphosphor, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 47(31), 5788-5791, 2008任職中研院著作;
|
| 2007 |
M.-T. Wei, K.-F. Hua, J. Hsu, A. Karmenyan, K.-Y. Tseng, C.-H. Wong, H.-Y. Hsu, A. Chiou, The Interaction of Lipopolysaccharide with Membrane Receptors on Macrophages Pretreated with Extract of Reishi Polysaccharides Measured by Optical Tweezers, OPTICS EXPRESS, vol. 15(17), 11020-11032, 2007任職中研院著作;
|
| 2007 |
S. R. Hanson, T. L. Hsu, E. Weerapana, K. Kishikawa, G. M. Simon, B. F. Cravatt, C. H. Wong, Tailored glycoproteomics and glycan site mapping using saccharide-selective bioorthogonal probes, J Am Chem Soc, vol. 129, 7266-7267, 2007任職中研院著作;
|
| 2007 |
Shie JJ, Fang JM, Wang SY, Tsai KC, Cheng YS, Yang AS, Hsiao SC, Su CY, Wong CH, Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity., Journal of the American Chemical Society, vol. 129(39), 11892-3, 2007任職中研院著作;
|
| 2007 |
J.-J. Shie, J.-M. Fang, S.-Y. Wang, K.-C. Tsai, Y.S.E. Cheng, A.-S. Yang, S.-C. Hsiao, C.Y. Su, C.-H. Wong, Synthesis of Tamiflu and its Phosphonate Congeners Possessing Potent Anti-Influenza Activity, J. Am. Chem. Soc, vol. 129(39), 11892-11893, 2007任職中研院著作;
|
| 2007 |
Y. Y. Yang, S. Ficht, A. Brik, C. H. Wong, Sugar-assisted ligation in glycoprotein synthesis, J Am Chem Soc, vol. 129, 7690-7701, 2007任職中研院著作;
|
| 2007 |
Brik A, Wong CH, Sugar-assisted ligation for the synthesis of glycopeptides., CHEMISTRY-A EUROPEAN JOURNAL, vol. 13(20), 5670-5675, 2007任職中研院著作;
|
| 2007 |
Y. M. Shao, W. B. Yang, H. P. Peng, M. F. Hsu, K. C. Tsai, T. H. Kuo, A. S. Yang, A. H. J. Wang, P. H. Liang, C. H. Lin, C. H. Wong, Structure-Based Design and Synthesis of Highly Potent SARS-CoV 3CL Protease Inhibitors, ChemBioChem, vol. 8(14), 1654-1657, 2007任職中研院著作;
|
| 2007 |
S. Ficht, R. J. Payne, A. Brik, C. H. Wong, Second Generation Sugar-Assisted Ligation: An Effective New Method for the Synthesis of Cysteine-Containing Glycopeptides, Angewandte chemie-international edition, vol. 46(31), 5975-5979, 2007任職中研院著作;
|
| 2007 |
S.M. Dean, W.A. Greenberg, C.-H. Wong, Recent Advances in Aldolase-catalyzed Asymmetric Synthesis, Advanced synthesis & catalysis, vol. 349, 1308-1320, 2007任職中研院著作;
|
| 2007 |
P. H. Liang, S. K. Wang, C. H. Wong, Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants, J Am Chem Soc, vol. 129(36), 11177-11184, 2007任職中研院著作;
|
| 2007 |
S. R. Hanson, W. A. Greenberg, C.-H. Wong, Probing Glycans with the Copper(I)-Catalyzed [3+2] Azide-Alkyne Cycloaddition, QSAR & Combinatorial Science, vol. 26, 1243-1252, 2007任職中研院著作;
|
| 2007 |
Y.-J. Chang, J.-R. Huang, Y.-C. Tsai, J.-T. Hung, D. Wu, M. Fujio, C.-H. Wong, A. L. Yu, Potent Immune-modulating and Anti-cancer Effects of NKT Cell Stimulatory Glycolipids, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 104(25), 10299-10304, 2007任職中研院著作;
|
| 2007 |
Casey CP, Wong CH, Partly cloudy with a chance of showers., ACS chemical biology, vol. 2(9), 573-6, 2007任職中研院著作;
|
| 2007 |
C. Casey, C.-H. Wong, Partly cloudy with a chance of showers, ACS Chem. Biol, vol. 2(9), 573-576, 2007任職中研院著作;
|
| 2007 |
Yu Z, Sawkar AR, Whalen LJ, Wong CH, Kelly JW, Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention., Journal of medicinal chemistry, vol. 50(1), 94-100, 2007任職中研院著作;
|
| 2007 |
Z. Yu, A.R. Sawkar, L.J. Whalen, C.-H. Wong, J.W. Kelly, Isofagomine- and 2,5-Anhydro-2,5-imino-D-glucitol-Based Glucocerebrosidase Pharmacological Chaperones for Gaucher Disease Intervention, J. Med. Chem, vol. 50, 94-100, 2007任職中研院著作;
|
| 2007 |
Sugiyama M, Hong Z, Greenberg WA, Wong CH, In vivo selection for the directed evolution of L-rhamnulose aldolase from L-rhamnulose-1-phosphate aldolase (RhaD)., Bioorganic & medicinal chemistry, vol. 15(17), 5905-5911, 2007任職中研院著作;
|
| 2007 |
M.-L. Michel, A.C. Keller, C. Paget, M. Fujio, F. Trottein, P.B. Savage, C.-H. Wong, E. Schneider, M. Dy, & M.C. Leite-de-Moraes, Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia, JOURNAL OF EXPERIMENTAL MEDICINE, vol. 204(5), 995-1001, 2007任職中研院著作;
|
| 2007 |
Michel ML, Keller AC, Paget C, Fujio M, Trottein F, Savage PB, Wong CH, Schneider E, Dy M, Leite-de-Moraes MC, Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia, Journal of experimental medicine, vol. 204(5), 995-1001, 2007任職中研院著作;
|
| 2007 |
Cheng KC, Huang HC, Chen JH, Hsu JW, Cheng HC, Ou CH, Yang WB, Chen ST, Wong CH, Juan HF, Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction., BMC genomics, vol. 8, 411, 2007任職中研院著作;
|
| 2007 |
K.-C. Cheng, H.-C. Huang, J.-H. Chen, J.-W. Hsu, H.-C. Cheng, C.-H. Ou, W.-B. Yang, S.-T. Chen, C.-H. Wong, H.-F. Juan, Ganoderma lucidum polysaccharides in human monocytic leukemia cells: from gene expression to network construction, BMC Genomics, vol. 8(1), 411, 2007任職中研院著作;
|
| 2007 |
Hua KF, Hsu HY, Chao LK, Chen ST, Yang WB, Hsu J, Wong CH, Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression., Journal of cellular physiology, vol. 212(2), 537-550, 2007任職中研院著作;
|
| 2007 |
K.-F. Hua, H.-Y Hsu, L.K. Chao, S.-T. Chen, W.-B. Yang, J. Hsu, C.H. Wong, Ganoderma Lucidum Polysaccharides Enhance CD14 Endocytosis of LPS and Promote TLR4 Signal Transduction of Cytokine Expression, J. Cell. Physiol, vol. 212, 537-550, 2007任職中研院著作;
|
| 2007 |
R. J. Payne, S. Ficht, S. Tang, A. Brik, Y.-Y. Yang, D. A. Case, C.-H. Wong, Extended Sugar-Assisted Ligations: Development, Scope and Applications, J. Am. Chem. Soc, vol. 129(44), 13527-13536, 2007任職中研院著作;
|
| 2007 |
M. Sugiyama, Z. Hong, P.-H. Liang, L.J. Whalen, W.A. Greenberg, C.-H. Wong, D-Fructose-6-Phosphate Aldolase Catalyzed One-Pot Synthesis of Iminocyclitols, J. Am. Chem. Soc, vol. 129(47), 14811-14817, 2007任職中研院著作;
|
| 2007 |
Bennett CS, Wong CH, Chemoenzymatic approaches to glycoprotein synthesis., Chemical Society reviews, vol. 36(8), 1227-38, 2007任職中研院著作;
|
| 2007 |
Kaltgrad E, Sen Gupta S, Punna S, Huang CY, Chang A, Wong CH, Finn MG, Blixt O, Anti-carbohydrate antibodies elicited by polyvalent display on a viral scaffold., Chembiochem : a European journal of chemical biology, vol. 8(12), 1455-62, 2007任職中研院著作;
|
| 2007 |
E. Kaltgrad, S. Sen Gupta, S. Punna, C.-Y. Huang, A. Chang, C.-H. Wong, M.G. Finn, O. Blixt, Anti-Carbohydrate Antibodies Elicited by Polyvalent Display on a Viral Scaffold, CHEMBIOCHEM, vol. 8(12), 1455-1462, 2007任職中研院著作;
|
| 2007 |
Polat T, Wong CH, Anomeric reactivity-based one-pot synthesis of heparin-like oligosaccharides., Journal of the American Chemical Society, vol. 129(42), 12795-800, 2007任職中研院著作;
|
| 2007 |
T. Polat, C.-H. Wong, Anomeric Reactivity-Based One-Pot Synthesis of Heparin-like Oligosaccharides, J. Am. Chem. Soc, vol. 129(42), 12795-12800, 2007任職中研院著作;
|
| 2007 |
T. L. Hsu, S. R. Hanson, K. Kishikawa, S. K. Wang, M. Sawa, C. H. Wong, Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells, Proceedings of the National Academy of Sciences of the United States of America, vol. 104, 2614-2619, 2007任職中研院著作;
|
| 2006 |
D. A. Thayer, C.-H. Wong, Vancomycin analogues containing monosaccharides exhibit improved antibiotic activity: a combined one-pot enzymatic glycosylation and chemical diversification strategy., CHEMISTRY-AN ASIAN JOURNAL, vol. 1(3), 445-452, 2006任職中研院著作;
|
| 2006 |
D. Thayer, C.-H. Wong, Vancomycin analogs with improved biological activity: a combined one-pot enzymatic glycosylation and chemical diversification strategy, Chemistry-An Asian Journal, vol. 1, 445-452, 2006任職中研院著作;
|
| 2006 |
Hong Z, Liu L, Hsu CC, Wong CH, Three-step synthesis of sialic acids and derivatives., ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 45(44), 7417-21, 2006任職中研院著作;
|
| 2006 |
M. H. Chuang, M. S. Wu, W. L. Lo, J. T. Lin, C. H. Wong, S. H. Chiou, The antioxidant protein alkylhydroperoxide reductase of Helicobacter pylori switches from a peroxide reductase to a molecular chaperone function, Proceedings of the national academy of sciences of the united states of america, vol. 103, 2552-2557, 2006任職中研院著作;
|
| 2006 |
S. Hanson, L. Whalen, C.-H. Wong, Synthesis and evaluation of general mechanism-based inhibitors of sulfatases based on (difluoro)methyl phenol sulfate and phenol cyclic sulfamate motifs, Bioorganic & medicinal chemistry, vol. 14(24):8386-95, 2006任職中研院著作;
|
| 2006 |
Brik A, Ficht S, Yang YY, Bennett CS, Wong CH, Sugar-assisted ligation of N-linked glycopeptides with broad sequence tolerance at the ligation junction., Journal of the American Chemical Society, vol. 128(46), 15026-33, 2006任職中研院著作;
|
| 2006 |
A. Brik, S. Ficht, Y.-Y. Yang, C. Bennett, C.-H. Wong, Sugar-Assisted ligation (SAL) of N-linked Glycopeptides with Broad Sequence Tolerance at the Ligation Junction, J. Am. Chem. Soc, vol. 128(46), 15026-33, 2006任職中研院著作;
|
| 2006 |
Brik A, Yang YY, Ficht S, Wong CH, Sugar-assisted glycopeptide ligation., Journal of the American Chemical Society, vol. 128(17), 5626-7, 2006任職中研院著作;
|
| 2006 |
M. Fujio, D. Wu, R. Garcia-Navarro, D. D. Ho, M. Tsuji, C. H. Wong, Structure-Based Discovery of Glycolipids for CD1d-Mediated NKT Cell Activation: Tuning the Adjuvant versus Immunosuppression Activity, J Am Chem Soc, vol. 128, 9022-9023, 2006任職中研院著作;
|
| 2006 |
Brik A, Ficht S, Wong CH, Strategies for the preparation of homogenous glycoproteins., Current opinion in chemical biology, vol. 10(6), 638-44, 2006任職中研院著作;
|
| 2006 |
C. Y. Wu, K. Y. King, C. J. Kuo, P. H. Liang, Y. T. Wu, M. Y. Ho, C. L. Liao, J. M. Fang, C. H. Wong, Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease, Chem Biol, vol. 13, 261-268, 2006任職中研院著作;
|
| 2006 |
Y. S. Cheng, K. H. Lo, H. H. Hsu, Y. M. Shao, W. B. Yang, C. H. Lin, C. H. Wong, Screening for HIV protease inhibitors by protection against activity-mediated cytotoxicity in Escherichia coli, J Virol Methods, vol. 137(1), 82-87, 2006任職中研院著作;
|
| 2006 |
K.-I. Lin, Y.-Y. Kao, H.-K. Kuo, W.-B. Yang, A. Chou, H.-H. Lin, A. L.-T. Yu, C.-H. Wong, Reishi Polysaccharides Induce Immunoglobulin Production Through the TLR4/TLR2-mediated Induction of Transcription Factor Blimp-1, J. Biol. Chem., vol. 281(34):24111-123, 2006任職中研院著作;
|
| 2006 |
J. C. Lee, C. Y. Wu, J. V. Apon, G. Siuzdak, C. H. Wong, Reactivity-Based One-Pot Synthesis of the Tumor-Associated Antigen N3 Minor Octasaccharide for the Development of a Photocleavable DIOS-MS Sugar Array, Angewandte chemie-international edition, vol. 45, 2753-2757, 2006任職中研院著作;
|
| 2006 |
J. C. Lee, W. A. Greenberg, C. H. Wong, Programmable reactivity-based one-pot oligosaccharide synthesis, Nat Protoc, vol. 1, 3143-3152, 2006任職中研院著作;
|
| 2006 |
S.C. Cheng, W.B. Yang, S.W. Chin, C.C. Lin, C.-H. Lin, Y.J. Chen, P.C. Lin, M.F. Wu, C.-H. Wong, S.L. Hsieh, Profiling of Polysaccharide-receptor Interaction with Recombinant Innate Immunity Receptor-Fe Fusion Proteins, Glycobiology, vol. 16(11), 1131-1132, 2006任職中研院著作;
|
| 2006 |
P. H. Liang, W. C. Cheng, Y. L. Lee, H. P. Yu, Y. T. Wu, Y. L. Lin, C. H. Wong, Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis, Chembiochem, vol. 7, 165-173, 2006任職中研院著作;
|
| 2006 |
Y. Kinjo, E. Tupin, D. Wu, M. Fujio, R. Garcia-Navarro, M. R.E.I. Benhnia, D.M. Zajonc, G. Ben-Menachem, G.D. Ainge, G.F. Painter, A. Khurana, K. Hoebe, S.M. Behar, B. Beutler, I. A. Wilson, M. Tsuji, T.J. Sellati, C.-H. Wong, M. Kronenberg, NKT cells recognize diacylglycerol antigens from pathogenic bacteria, NATURE IMMUNOLOGY, vol. 7(9), 978-986, 2006任職中研院著作;
|
| 2006 |
Kinjo Y, Tupin E, Wu D, Fujio M, Garcia-Navarro R, Benhnia MR, Zajonc DM, Ben-Menachem G, Ainge GD, Painter GF, Khurana A, Hoebe K, Behar SM, Beutler B, Wilson IA, Tsuji M, Sellati TJ, Wong CH, Kronenberg M, Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria., Nature immunology, vol. 7(9), 978-86, 2006任職中研院著作;
|
| 2006 |
Huang KT, Wu BC, Lin CC, Luo SC, Chen C, Wong CH, Lin CC, Multi-enzyme one-pot strategy for the synthesis of sialyl Lewis X-containing PSGL-1 glycopeptide., Carbohydrate research, vol. 341(12), 2151-5, 2006任職中研院著作;
|
| 2006 |
K.-T. Huang, B.-C. Wu, C.-C. Lin, S.-C. Luo, C. Chen, C.-H. Wong, C.-C. Lin, Multi-enzyme one-pot strategy for the synthesis of sialyl Lewis X-containing PSGL-1 glycopeptide, CARBOHYDRATE RESEARCH, vol. 341(12), 2151-2155, 2006任職中研院著作;
|
| 2006 |
A. Brik, C.-Y. Wu, C.-H. Wong, Microtiter plate based chemistry and in situ screening: a useful approach for enzymatic inhibitor discovery, Org. Biomol. Chem., vol. 4:1446–14, 2006任職中研院著作;
|
| 2006 |
Sawa M, Hsu TL, Itoh T, Sugiyama M, Hanson SR, Vogt PK, Wong CH, Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo., Proceedings of the National Academy of Sciences of the United States of America, vol. 103 (33), 12371-12376, 2006任職中研院著作;
|
| 2006 |
Qiu H, Gabrielsen A, Agardh HE, Wan M, Wetterholm A, Wong CH, Hedin U, Swedenborg J, Hansson GK, Samuelsson B, Paulsson-Berne G, Haeggstrom JZ, Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability., Proceedings of the National Academy of Sciences of the United States of America, vol. 103(21), 8161-6, 2006任職中研院著作;
|
| 2006 |
H. Qiul, A. Gabrielsen, H.E. Agardh, M. Wan, A. Wetterholm, C.-H. Wong, U. Hedin, J. Swedenborg, G.K. Hansson, B. Samuelsson, G. Paulsson-Berne, J.Z. Haeggstrom, Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlate with symptoms of plaque instability, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 103(21), 8161-8166, 2006任職中研院著作;
|
| 2006 |
Liang FS, Greenberg WA, Hammond JA, Hoffmann J, Head SR, Wong CH, Evaluation of RNA-binding specificity of aminoglycosides with DNA microarrays., Proceedings of the National Academy of Sciences of the United States of America, vol. 103(33), 12311-6, 2006任職中研院著作;
|
| 2006 |
F.-S. Liang, W. A. Greenberg, J. A. Hammond, J. Hoffmann, S. R. Head, C.-H. Wong, Evaluation of RNA Binding Specificity of Aminoglycosides with DNA Microarrays, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 103(33), 12311-12316, 2006任職中研院著作;
|
| 2006 |
F. S. Liang, A. Brik, Y. C. Lin, J. H. Elder, C. H. Wong, Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates, Bioorganic & medicinal chemistry, vol. 14, 1058-1062, 2006任職中研院著作;
|
| 2006 |
L.J. Whalen, C-H. Wong, Enzymes in Organic Synthesis: Aldolase-mediated Synthesis of Iminocyclitols and Novel Heterocycles, Aldrichimica Acta, vol. 39(3), 63-71, 2006任職中研院著作;
|
| 2006 |
M.G. Sanna, S.-K. Wang, P.J. Gonzalez-Cabrera, A. Don, D. Marsolais, M.P. Matheu, S.H. Wei, I. Parker, E. Jo, W.-C. Cheng, M.D. Cahalan, C.-H. Wong, H. Rosen, Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo, Nature Chemical Biology, vol. 2(8):434-441, 2006任職中研院著作;
|
| 2006 |
D. Wu, D.M. Zajonc, M. Fujio, B.A. Sullivan, Y. Kinjo, M. Kronenberg, I.A. Wilson, C.-H. Wong, Design of NKT-cell activators: Structure and function of a microbial glycosphingolipid bound to mouse CD1d, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 103(11), 3972-3977, 2006任職中研院著作;
|
| 2006 |
Wu D, Zajonc DM, Fujio M, Sullivan BA, Kinjo Y, Kronenberg M, Wilson IA, Wong CH, Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d., Proceedings of the National Academy of Sciences of the United States of America, vol. 103(11), 3972-7, 2006任職中研院著作;
|
| 2006 |
L. Liu, Z.-Y. Hong, C.-H. Wong, Convergent Glycopeptide Synthesis by Traceless Staudinger Ligation and Enzymatic Coupling, Chembiochem, vol. 7, 429-432, 2006任職中研院著作;
|
| 2006 |
M. Brigl, P. van den Elzen, X. Chen, J. H. Meyers, D. Wu, C. H. Wong, F. Reddington, P. A. Illarianov, G. S. Besra, M. B. Brenner, J. E. Gumperz, Conserved and Heterogeneous Lipid Antigen Specificities of CD1d-Restricted NKT Cell Receptors, J Immunol, vol. 176, 3625-3634, 2006任職中研院著作;
|
| 2006 |
Liu H, Wong CH, Characterization of a transglycosylase domain of Streptococcus pneumoniae PBP1b., Bioorganic & medicinal chemistry, vol. 14(21), 7187-95, 2006任職中研院著作;
|
| 2006 |
H. Liu, C.-H. Wong, Characterization of a transglycosylase domain of Streptococcus pneumoniae PBP1b, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 14, 7187-7195, 2006任職中研院著作;
|
| 2006 |
C. Y. Huang, D. A. Thayer, A. Y. Chang, M. D. Best, J. Hoffman, S. Head, C. H. Wong, Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen, Proceedings of the national academy of sciences of the united states of america, vol. 103, 15-20, 2006任職中研院著作;
|
| 2006 |
M. Sugiyama, L.J. Whalen, Z.-Y. Hong, W.A. Greenberg, C.-H. Wong, Borate as a Phosphate Ester Mimic in Aldolase-Catalyzed Reactions: Practical Syntheses of L-Fructose and L-Iminocyclitols, Advanced Synthesis and Catalysis, vol. 348, 2555-2559, 2006任職中研院著作;
|
| 2006 |
Lin YC, Brik A, de Parseval A, Tam K, Torbett BE, Wong CH, Elder JH, Altered gag polyprotein cleavage specificity of feline immunodeficiency virus/human immunodeficiency virus mutant proteases as demonstrated in a cell-based expression system., Journal of virology, vol. 80(16), 7832-43, 2006任職中研院著作;
|
| 2006 |
Y.-C. Lin, A. Brik, A. P., K. Tam, A. Parseval, B.E. Torbett, C.-H. Wong, J.H. Elder, Altered Gag Polyprotein Cleavage Specificity of Feline Immunodeficiency Virus/Human Immunodeficiency Virus Mutant Proteases as Demonstrated in a Cell-Based Expression System, JOURNAL OF VIROLOGY, vol. 80(16), 7832-7843, 2006任職中研院著作;
|
| 2006 |
H.-Y. Hsu, K.-F. Hua, Y.-C. Su, L.-C. Chu, H.-W. Chiu, C.-H. Wong, S.U-S. Yang, L. K. Chao, Alkali-soluble polysaccharides of Rhizoclonium riparium alga induces IL-1 gene expression via protein kinase signaling pathways, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 54, 3558-3565, 2006任職中研院著作;
|
| 2006 |
Hsu HY, Hua KF, Su YC, Chu LC, Su SC, Chiu HW, Wong CH, Chen ST, Shieh CW, Yang SS, Chen YM, Chao LK, Alkali-soluble polysaccharides of Rhizoclonium riparium alga induce IL-1 gene expression via protein kinase signaling pathways., Journal of agricultural and food chemistry, vol. 54(10), 3558-65, 2006任職中研院著作;
|
| 2006 |
L. Liu, C. S. Bennett, C. H. Wong, Advances in glycoprotein synthesis, Chemical communications, vol. 7, 21-33, 2006任職中研院著作;
|
| 2006 |
A. Brik, S. Ficht, C.-H. Wong, Strategies for the Preparation of Homogenous Glycoproteins, CURRENT OPINION IN CHEMICAL BIOLOGY, vol. 10(6):638-644., 2006任職中研院著作;
|
| 2005 |
C. Y. Wu, A. Brik, S. K. Wang, Y. H. Chen, C. H. Wong, Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ, Chembiochem, vol. 6, 2176-2180, 2005任職中研院著作;
|
| 2005 |
Brik, A., Wu, C. Y., Best, M. D., Wong, C. H., Tetrabutylammonium fluoride-assisted rapid N(9)-alkylation on purine ring: Application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ., Bioorganic & medicinal chemistry, vol. 13(15), 4622-4626, 2005任職中研院著作;
|
| 2005 |
G. T. Fan, Y. S. Pan. K. C. Lu, Y. P. Cheng, W. C. Lin, S. Lin, S. H. Lin, C. H. Wong, J. M. Fang, C. C. Lin Wong, C. H., Fang, J. M., C. C. Lin, Synthesis of alpha-galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes., Tetrahedron, vol. 61, 1855-1862, 2005任職中研院著作;
|
| 2005 |
G. T. Fan, Y. S. Pan. K. C. Lu, Y. P. Cheng, W. C. Lin, S. Lin, S. H. Lin, C. H. Wong, J. M. Fang, C. C. Lin, Synthesis of ?galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes, Tetrahedron, vol. 61, 1855-1862, 2005任職中研院著作;
|
| 2005 |
G. W. Xing, D. Wu, M. A. Poles, A. Horowitz, M. Tsuji, D. D. Ho, C. H. Wong, Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides, Bioorganic & medicinal chemistry, vol. 13, 2907-2916, 2005任職中研院著作;
|
| 2005 |
Zajonc DM, Maricic I, Wu D, Halder R, Roy K, Wong CH, Kumar V, Wilson IA, Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity., The Journal of experimental medicine, vol. 202(11), 1517-26, 2005任職中研院著作;
|
| 2005 |
S. H. Wei, H. Rosen, M. P. Matheu, M. G. Sanna, S. K. Wang, E. Jo, C. H. Wong, I. Parker, M. D. Cahalan, Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses, Nat Immunol, vol. 6, 1228-1235, 2005任職中研院著作;
|
| 2005 |
Y. Kinjo, D. Wu, G. Kim, G. W. Xing, M. A. Poles, D. D. Ho, M. Tsuji, K. Kawahara, C. H. Wong, M. Kronenberg, Recognition of bacterial glycosphingolipids by natural killer T cells, Nature, vol. 434, 520-525, 2005任職中研院著作;
|
| 2005 |
Sinchaikul, S., Pan, F. M., Cheng, C. W., Wong, C. H., Fang, J. M., Tseng, M. J., Chen, S. T., Protein microarray using alpha-amino acids as metal tags on chips., Bioorg Med Chem Lett, vol. 15(5), 1413-1416, 2005任職中研院著作;
|
| 2005 |
C. H. Wong, Protein glycosylation: new challenges and opportunities, J Org Chem, vol. 70, 4219-4225, 2005任職中研院著作;
|
| 2005 |
J. J. Shie, J. M. Fang, T. H. Kuo, C. J. Kuo, P. H. Liang, H. J. Huang, Y. T. Wu, J. T. Jan, Y. S.E. Cheng, C. H. Wong, Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters., Bioorganic & medicinal chemistry, vol. 13, 5240–5252, 2005任職中研院著作;
|
| 2005 |
M. M. Numa, L. V. Lee, C. C. Hsu, K. E. Bower, C. H. Wong, Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ, Chembiochem, vol. 6, 1002-1006, 2005任職中研院著作;
|
| 2005 |
Sawkar AR, Adamski-Werner SL, Cheng WC, Wong CH, Beutler E, Zimmer KP, Kelly JW, Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles., Chemistry & biology, vol. 12(11), 1235-44, 2005任職中研院著作;
|
| 2005 |
A.R. Sawkar, S.L. Adamski-Werner, W.-C. Cheng, C.-H. Wong, E. Beutler, K.-P. Zimmer, J.W. Kelly, Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles, Chem. Biol, vol. 12(11), 1235–1244, 2005任職中研院著作;
|
| 2005 |
M. Fridman, V. Belakhov, L. V. Lee, F. S. Liang, C. H. Wong, T. Baasov, Dual effect of synthetic aminoglycosides: antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor, Angewandte chemie-international edition, vol. 44, 447-452, 2005任職中研院著作;
|
| 2005 |
D. A. Calarese, H. K. Lee, C. Y. Huang, M. D. Best, R. D. Astronomo, R. L. Stanfield, H. Katinger, D. R. Burton, C. H. Wong, I. A. Wilson, Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 13372–13377, 2005任職中研院著作;
|
| 2005 |
J. J. Shie, J. M. Fang, C. J. Kuo, T. H. Kuo, P. H. Liang, H. J. Huang, W. B. Yang, C. H. Lin, J. L. Chen, Y. T. Wu, C. H. Wong, Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease, J Med Chem, vol. 48, 4469-4473, 2005任職中研院著作;
|
| 2005 |
C.-C. Hsu, Y. Zhang, M. Wada, D. Franke, C.-H. Wong, Directed evolution of d-sialic acid aldolase l-3-deoxy-manno-2-octulosonic acid (l-KDO) aldolases, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 9122-9126, 2005任職中研院著作;
|
| 2005 |
C. C. Hsu, Y. Zhang, M. Wada, D. Franke, C. H. Wong, Directed evolution of D-sialic acid aldolase L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolases, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 9122–9126, 2005任職中研院著作;
|
| 2005 |
D. Wu, G. W. Xing, M. A. Poles, A. Horowitz, Y. Kinjo, B. Sullivan, V. Bodmer Narkevitch, O. Plettenburg, M. Kronenberg, M. Tsuji, D. D. Ho, C. H. Wong, Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 1351-1356, 2005任職中研院著作;
|
| 2005 |
Scanlan C, Calarese D, Lee HK, Blixt O, Wong CH, Wilson I, Burton D, Dwek R, Rudd P, Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design., Advances in experimental medicine and biology, vol. 564, 7-8, 2005任職中研院著作;
|
| 2005 |
T. J. Tolbert, D. Franke, C. H. Wong, A new strategy for glycoprotein synthesis: ligation of synthetic glycopeptides with truncated proteins expressed in E. coli as TEV protease cleavable fusion protein, Bioorganic & medicinal chemistry, vol. 13, 909-915, 2005任職中研院著作;
|
| 2005 |
H. N. Yu, D. A. Thayer, M. C. Galan, C. H. Wong, A general strategy toward S-linked glycopeptides, Angewandte chemie-international edition, vol. 44, 4596-4599, 2005任職中研院著作;
|
| 2005 |
A. Brik, J. Alexandratos, Y. C. Lin, J. H. Elder, A. J. Olson, A. Wlodawer, D. S. Goodsell, C. H. Wong, 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors, Chembiochem, vol. 6, 1167-1169, 2005任職中研院著作;
|
| 2004 |
F. S. Liang, S. K. Wang, T. Nakatani, C. H. Wong, Targeting RNAs with tobramycin analogues, Angewandte chemie-international edition, vol. 43, 6496-6500, 2004
|
| 2004 |
J. Liu, M.M.D. Numa, H. Liu, S. J. Huang, P. Sears, A. R. Shikhman, C. H. Wong, Synthesis and high-throughput screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis, J Org Chem, vol. 69, 6273-6283, 2004
|
| 2004 |
E. Chapman, M. D. Best, S. R. Hanson, C. H. Wong, Sulfotransferases: structure, mechanism, biological activity, inhibition, and synthetic utility, Angewandte chemie-international edition, vol. 43, 3526-3548, 2004
|
| 2004 |
S. R. Hanson, M. D. Best, C. H. Wong, Sulfatases: structure, mechanism, biological activity, inhibition, and synthetic utility, Angewandte chemie-international edition, vol. 43, 5736-5763, 2004
|
| 2004 |
T. J. Tolbert, C. H. Wong, Subtilisin-catalyzed glycopeptide condensation, Methods Mol Biol, vol. 283, 267-280, 2004
|
| 2004 |
H. S. Chen, Y. F. Tsai, S. Lin, C. C. Lin, K. H. Khoo, C. H. Lin, C. H. Wong, Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides, Bioorganic & medicinal chemistry, vol. 12, 5595-5601, 2004任職中研院著作;
|
| 2004 |
C. Y. Wu, J. T. Jan, S. H. Ma, C. J. Kuo, H. F. Juan, Y. S. Cheng, H. H. Hsu, H. C. Huang, D. Wu, A. Brik, F. S. Liang, R. S. Liu, J. M. Fang, S. T. Chen, P. H. Liang, C. H. Wong, Small molecules targeting severe acute respiratory syndrome human coronavirus, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 101, 10012-10017, 2004任職中研院著作;
|
| 2004 |
C.-Y. Wu, J.-T. Jan, H.-H. Ma, C.-J. Kuo, H.-F. Juan, Y.-S. E. Cheng, H.-H. Hsu, H.-C. Huang, D. Wu, A. Brik, F.-S. Liang, R.-S. Liu, J.-M. Fang, S.-T. Chen, P.-H. Liang, C.-H. Wong, Small molecules targeting severe acute respiratory syndrome (SARS) human coronavirus, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 101, 10012-10017, 2004任職中研院著作;
|
| 2004 |
R. Xu, S. R. Hanson, Z. Zhang, Y. Y. Yang, P. G. Schultz, C. H. Wong, Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-O-threonine into protein in Escherichia coli, J Am Chem Soc, vol. 126, 15654-15655, 2004
|
| 2004 |
J. Liu, C. C. Hsu, C. H. Wong, Sequential aldol condensation catalyzed by DERA mutant Ser238Asp and a formal total synthesis of atorvastatin, Tetrahedron Lett, vol. 45, 2439-2441, 2004
|
| 2004 |
P. T. Nyffeler, S. G. Duron, M. D. Burkart, S. P. Vincent, C. H. Wong, Selectflour : Mechanistic Insight and Application, Angewandte chemie-international edition, vol. 44, 192-214, 2004
|
| 2004 |
C. H. Chou, C. S. Wu, C. H. Chen, L. D. Lu, S. S. Kulkarni, C. H. Wong, S. C. Hung, Regioselective glycosylation of neamine core: a facile entry to kanamycin B related analogues, Org Lett, vol. 6, 585-588, 2004任職中研院著作;
|
| 2004 |
H. K. Lee, C. N. Scanlan, C. Y. Huang, A. Y. Chang, D. A. Calarese, R. A. Dwek, P. M. Rudd, D. R. Burton, I. A. Wilson, C. H. Wong, Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody, Angewandte chemie-international edition, vol. 43, 1000-1003, 2004
|
| 2004 |
M. D. Best, A. Brik, E. Chapman, L. V. Lee, W. C. Cheng, C. H. Wong, Rapid Discovery of Potent Sulfotransferase Inhibitors by Diversity-Oriented Reaction in Microplates Followed by in situ Screening, Chembiochem, vol. 5, 811-819, 2004
|
| 2004 |
O. Blixt, S. Head, T. Mondala, C. Scanlan, M.E. Huflejt, R. Alvarez, M.C. Bryan, F. Fazio, D. Calarese, J. Stevens, N. Razi, I. van Die, D. Burton, I.A. Wilson, R. Cummings, N. Bovin, C.-H. Wong, J.C. Paulson, Printed covalent glycan array for ligand profiling of diverse glycan binding proteins, Proceedings of the National Academy of Sciences of the United States of America, vol. 101, 17033-17038, 2004任職中研院著作;
|
| 2004 |
C. M. Chien, J. L. Cheng, W. T. Chang, M. H. Tien, W. Y. Wu, Y. H. Chang, H. Y. Chang, J. F. Hsieh, C. H. Wong, S. T. Chen, Polysaccharides of Ganoderma lucidum Alter Cell Immunophenotypic Expression and Enhance CD56+ NK-Cell Cytotoxicity in Cord Blood, Bioorganic & medicinal chemistry, vol. 12, 5603-5609, 2004任職中研院著作;
|
| 2004 |
J. H. Chen, Y. W. Chang, C. W. Yao, T. S. Chiueh, S. C. Huang, K. Y. Chien, A. Chen, F. Y. Chang, C. H. Wong, Y. J. Chen, Plasma proteome of severe acute respiratory syndrome analyzed by two-dimensional gel electrophoresis and mass spectrometry, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 101, 17039-17044, 2004任職中研院著作;
|
| 2004 |
H. N. Yu, J. Furukawa, T. Ikeda, C. H. Wong, Novel efficient routes to heparin monosaccharides and disaccharides achieved via regio- and stereoselective glycosidation, Org Lett, vol. 6, 723-726, 2004
|
| 2004 |
S. G. Duron, T. Polat, C. H. Wong, N-(phenylthio)-epsilon-caprolactam: a new promoter for the activation of thioglycosides, Org Lett, vol. 6, 839-841, 2004
|
| 2004 |
T. J. Cheng, A. Brik, C. H. Wong, C. C. Kan, Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitos in Escherichia coli, Antimicrob Agents Chemother, vol. 48, 2437-2447, 2004
|
| 2004 |
H. Lin, D. A. Thayer, C. H. Wong, C. T. Walsh, Macrolactamization of glycosylated peptide thioesters by the thioesterase domain of tyrocidine synthetase, Chem Biol, vol. 11, 1635-1642, 2004
|
| 2004 |
L. V. Lee, K. E. Bower, F. S. Liang, J. Shi, D. Wu, S. J. Sucheck, P. K. Vogt, C. H. Wong, Inhibition of the proteolytic activity of anthrax lethal factor by aminoglycosides, J Am Chem Soc, vol. 126, 4774-4775, 2004
|
| 2004 |
V. P. Mocharla, B. Colasson, L. V. Lee, S. Romper, K. B. Sharpless, C. H. Wong, H. C. Kolb, In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrate II, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 44, 116–120, 2004
|
| 2004 |
M. C. Bryan, L. V. Lee, C. H. Wong, High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays, Bioorg Med Chem Lett, vol. 14, 3185-3188, 2004
|
| 2004 |
C. W. Cheng, K. C. Lin, F. M. Pan, S. Sinchaikul, C. H. Wong, W. C. Su, C. H. Hsu, S. T. Chen, Facile synthesis of metal-chelating peptides on chip for protein array, Bioorg Med Chem Lett, vol. 14, 1987-1990, 2004
|
| 2004 |
H. Y. Hsu, K. F. Hua, C. C. Lin, C. H. Lin, C. H. Wong, Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways, J Immunol, vol. 173, 5989-5999, 2004任職中研院著作;
|
| 2004 |
C. H. Wong, Enzymatic synthesis of L-fucose and L-fucose analogs, US Patent, vol. #6,713,287, 2004
|
| 2004 |
C. F. Chang, C. W. Ho, C. Y. Wu, C. H. Wong, C. H. Lin, Discovery of picomolar slow tight-binding inhibitors of alpha-fucosidase, Chem Biol, vol. 11, 1301-1306, 2004任職中研院著作;
|
| 2004 |
D. Franke, C. C. Hsu, C. H. Wong, Directed evolution of aldolases, Methods Enzymol, vol. 388, 224-238, 2004
|
| 2004 |
F. Agnelli, S. J. Sucheck, K. A. Marby, D. Rabuka, S. L. Yao, P. S. Sears, F. S. Liang, C. H. Wong, Dimeric aminoglycosides as antibiotics, Angewandte chemie-international edition, vol. 43, 1562-1566, 2004
|
| 2004 |
P. T. Nyffeler, L. Eltepu, N. A. Boyle, C. H. Wong, A. Eschenmoser, R. A. Lerner, P. J. Wentworth, Dihydrogen trioxide (HOOOH) is generated during the thermal reaction between hydrogen peroxide and ozone, Angewandte chemie-international edition, vol. 43, 4656-4659, 2004
|
| 2004 |
M. P. Heck, S. P. Vincent, B. W. Murray, F. Bellamy, C. H. Wong, C. Mioskowski, Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: potent competitive inhibitors of mannosidases, J Am Chem Soc, vol. 126, 1971-1979, 2004
|
| 2004 |
M. C. Bryan, F. Fazio, H. K. Lee, C. Y. Huang, A. Chang, M. Best, D. A. Calarese, O. Blixt, J. C. Paulson, D. Burton, I. A. Wilson, C. H. Wong, Covalent display of oligosaccharide arrays in microtiter plates, J Am Chem Soc, vol. 126, 8640-8641, 2004
|
| 2004 |
T. J. Tolbert, C. H. Wong, Conjugation of glycopeptide thioesters to expressed protein fragments: semisynthesis of glycosylated interleukin-2, Methods Mol Biol, vol. 283, 255-266, 2004
|
| 2004 |
S. R. Hanson, M. D. Best, M. C. Bryan, C. H. Wong, Chemoenzymatic synthesis of oligosaccharides and glycoproteins, Trends Biochem Sci, vol. 29, 656-663, 2004
|
| 2004 |
T. J. Tolbert, C. H. Wong, Carbohydrate chains: enzymatic and chemical synthesis, Encyclopedia of Biological Chemistry, vol. 307-313, 2004
|
| 2004 |
F. Fazio, M. C. Bryan, H. K. Lee, A. Chang, C. H. Wong, Assembly of sugars on polystyrene plates: a new facile microarray fabrication technique, Tetrahedron Lett, vol. 45, 2689-2692, 2004
|
| 2004 |
A. Heine, J. G. Luz, C. H. Wong, I. A. Wilson, Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolution, J Mol Biol, vol. 343, 1019-1034, 2004
|
| 2004 |
M. C. Bryan, C. H. Wong, Aminoglycoside array for the high-throughput analysis of small molecule-RNA interactions, Tetrahedron Lett, vol. 45, 3639-3642, 2004
|
| 2004 |
D. Klostermeier, P. Sears, C. H. Wong, D. P. Millar, J. R. Williamson, A three-fluorophore FRET assay for high-throughput screening of small-molecule inhibitors of ribosome assembly, Nucleic Acids Res, vol. 32, 2707-2715, 2004任職中研院著作;
|
| 2004 |
Z. Zhang, J. Gildersleeve, Y. Y. Yang, R. Xu, J. A. Loo, S. Uryu, C. H. Wong, P. G. Schultz, A new strategy for the synthesis of glycoproteins, Science, vol. 303, 371-373, 2004
|
| 2003 |
T. K. Mong, L. V. Lee, J. R. Brown, J. D. Esko, C. H. Wong, Synthesis of N-acetyllactosamine derivatives with variation in the aglycon moiety for the study of inhibition of sialyl Lewis x expression, Chembiochem, vol. 4, 835-840, 2003
|
| 2003 |
C. H. Wong, M. C. Bryan, P. T. Nyffeler, H. T. Liu, E. Chapman, Synthesis of carbohydrate-based antibiotics, Pure Appl Chem, vol. 75, 179-186, 2003
|
| 2003 |
C. H. Wong, F. S. Liang, Surface plasmon resonance study of RNA-aminoglycoside interactions, Methods in Enzymology, vol. 362, 340-353, 2003
|
| 2003 |
C. H. Wong, M. C. Bryan, Sugar arrays in microtiter plates, Methods in Enzymology, vol. 362, 218-225, 2003
|
| 2003 |
G. DeSantis, J. Liu, D. P. Clark, A. Heine, I. A. Wilson, C. H. Wong, Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 43-52, 2003
|
| 2003 |
F. Fazio, C. H. Wong, RuCl3-promoted amide formation from azides and thioacids, Tetrahedron Lett, vol. 44, 9083-9085, 2003
|
| 2003 |
T. K. Mong, H. K. Lee, S. G. Duron, C. H. Wong, Reactivity-based one-pot total synthesis of fucose GM1 oligosaccharide: a sialylated antigenic epitope of small-cell lung cancer, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 100, 797-802, 2003
|
| 2003 |
C. Y. Wu, C. F. Chang, J. S. Chen, C. H. Wong, C. H. Lin, Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 42, 4661-4664, 2003任職中研院著作;
|
| 2003 |
A. Brik, J. Muldoon, Y. C. Lin, J. H. Elder, D. S. Goodsell, A. J. Olson, V. V. Fokin, K. B. Sharpless, C. H. Wong, Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors, Chembiochem, vol. 4, 1246-1248, 2003任職中研院著作;
|
| 2003 |
C. H. Wong, Programmable one-pot oligosaccharide synthesis, US Patent, vol. #6,538,117, 2003
|
| 2003 |
D. Franke, T. Machajewski, C. C. Hsu, C. H. Wong, One-pot synthesis of L-Fructose using coupled multienzyme systems based on rhamnulose-1-phosphate aldolase, J Org Chem, vol. 68, 6828-6831, 2003
|
| 2003 |
C. H. Wong, New developments in biocatalysis, Adv Synth Catal, vol. 345, 651-651, 2003
|
| 2003 |
E. Chapman, M. C. Bryan, C. H. Wong, Mechanistic studies of beta-arylsulfotransferase IV, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 100, 910-915, 2003
|
| 2003 |
A. Brik, C. H. Wong, HIV-1 protease: mechanism and drug discovery, Org Biomol Chem, vol. 1, 5-14, 2003
|
| 2003 |
T. J. Tolbert, C. H. Wong, Glycoprotein synthesis, In: Yearbook of Science & Technology, vol. 159-162, 2003
|
| 2003 |
M. Wada, C. C. Hsu, D. Franke, M. Mitchell, A. Heine, I. Wilson, C. H. Wong, Directed evolution of N-acetylneuraminic acid aldolase to catalyze enantiomeric aldol reactions, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 2091-2098, 2003
|
| 2003 |
C. C. Mak, A. Brik, D. L. Lerner, J. H. Elder, G. M. Morris, A. J. Olson, C. H. Wong, Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteases, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 2025-2040, 2003
|
| 2003 |
T. Feizi, F. Fazio, W. Chai, C. H. Wong, Carbohydrate microarrays - a new set of technologies at the frontiers of glycomics, CURRENT OPINION IN STRUCTURAL BIOLOGY, vol. 13, 637-645, 2003
|
| 2003 |
M. G. Silvestri, G. Desantis, M. Mitchell, C. H. Wong, Asymmetric aldol reactions using aldolases, In: Topics in Stereochemistry, Vol 23, vol. 23, 267-342, 2003
|
| 2003 |
H. Liu, T. K. Ritter, R. Sadamoto, P. S. Sears, M. Wu, C. H. Wong, Acceptor specificity and inhibition of the bacterial cell-wall glycosyltransferase MurG, Chembiochem, vol. 4, 603-609, 2003
|
| 2003 |
T. K. Ritter, K. K. Mong, H. Liu, T. Nakatani, C. H. Wong, A programmable one-pot oligosaccharide synthesis for diversifying the sugar domains of natural products: a case study of vancomycin, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 42, 4657-4660, 2003
|
| 2003 |
L. V. Lee, M. L. Mitchell, S. J. Huang, V. V. Fokin, K. B. Sharpless, C. H. Wong, A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry, J Am Chem Soc, vol. 125, 9588-9589, 2003
|
| 2003 |
T. K. Mong, C. Y. Huang, C. H. Wong, A new reactivity-based one-pot synthesis of N-acetyllactosamine oligomers, J Org Chem, vol. 68, 2135-2142, 2003
|
| 2003 |
H. Liu, L. Wang, A. Brock, C. H. Wong, P. G. Schultz, A method for the generation of glycoprotein mimetics, J Am Chem Soc, vol. 125, 1702-1703, 2003
|
| 2002 |
P. T. Nyffeler, C. H. Liang, K. M. Koeller, C. H. Wong, The chemistry of amine-azide interconversion: catalytic diazotransfer and regioselective azide reduction, J Am Chem Soc, vol. 124, 10773-10778, 2002
|
| 2002 |
F. Fazio, M. C. Bryan, O. Blixt, J. C. Paulson, C. H. Wong, Synthesis of sugar arrays in microtiter plate, J Am Chem Soc, vol. 124, 14397-14402, 2002
|
| 2002 |
O. Plettenburg, V. Bodmer Narkevitch, C. H. Wong, Synthesis of alpha-galactosyl ceramide, a potent immunostimulatory agent, J Org Chem, vol. 67, 4559-4564, 2002
|
| 2002 |
M. L. Mitchell, F. Tian, L. V. Lee, C. H. Wong, Synthesis and evaluation of transition-state analogue inhibitors of alpha-1,3-fucosyltransferase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 3041-3044, 2002
|
| 2002 |
M. L. Mitchell, L. V. Lee, C. H. Wong, Synthesis and evaluation of six-membered GDP-iminocyclitol, Tetrahedron Lett, vol. 43, 5691-5693, 2002
|
| 2002 |
Y. Y. Wang, K. H. Khoo, S. T. Chen, C. C. Lin, C. H. Wong, C. H. Lin, Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 10, 1057-1062, 2002
|
| 2002 |
J. J. Liu, G. DeSantis, C. H. Wong, Structure-based rationalization of aldolase-catalyzed asymmetric synthesis, CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, vol. 80, 643-645, 2002
|
| 2002 |
T. Kanemitsu, C. H. Wong, O. Kanie, Solid-phase synthesis of oligosaccharides and on-resin quantitative monitoring using gated decoupling (13)C NMR, J Am Chem Soc, vol. 124, 3591-3599, 2002
|
| 2002 |
J. Liu, C. H. Wong, Selectfluor(TM)-mediated allylstannation of aldehydes and imines, Tetrahedron Lett, vol. 43, 3915-3917, 2002
|
| 2002 |
M. C. Bryan, O. Plettenburg, P. Sears, D. Rabuka, S. Wacowich Sgarbi, C. H. Wong, Saccharide display on microtiter plates, Chem Biol, vol. 9, 713-720, 2002
|
| 2002 |
Z. Zhang, C. H. Wong, Regioselective benzoylation of sugars mediated by excessive Bu2SnO: observation of temperature promoted migration, Tetrahedron, vol. 58, 6513-6519, 2002
|
| 2002 |
K. K. Mong, C. H. Wong, Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: a colon-rectal cancer antigen determinant, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 4087-4090, 2002
|
| 2002 |
O. Plettenburg, C. Mui, V. Bodmer Narkevitch, C. H. Wong, Rapid preparation of glycolipid libraries by cross metathesis, Adv Synth Catal, vol. 344, 622-626, 2002
|
| 2002 |
T. J. Tolbert, C. H. Wong, New methods for proteomic research: Preparation of proteins with N-terminal cysteines for labeling and conjugation, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 2171-2174, 2002
|
| 2002 |
C. H. Wong, Mannosyl transfer with regeneration of GDP-mannose, US Patent, vol. #6,485,930, 2002
|
| 2002 |
C. H. Wong, F. MorisVaras, Hydroxyazepanes as inhibitors of glycosidases and HIV protease, US Patent, vol. #6,462,193, 2002
|
| 2002 |
M. M. Thunnissen, B. Andersson, B. Samuelsson, C. H. Wong, J. Z. Haeggstrom, Crystal structures of leukotriene A4 hydrolase in complex with captopril and two competitive tight-binding inhibitors, Faseb J, vol. 16, 1648-1650, 2002
|
| 2002 |
A. R. Sawkar, W. C. Cheng, E. Beutler, C. H. Wong, W. E. Balch, J. W. Kelly, Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 99, 15428-15433, 2002
|
| 2002 |
R. Sadamoto, K. Niikura, P. S. Sears, H. Liu, C. H. Wong, A. Suksomcheep, F. Tomita, K. Monde, S. Nishimura, Cell-wall engineering of living bacteria, J Am Chem Soc, vol. 124, 9018-9019, 2002
|
| 2002 |
C. T. Guo, X. L. Sun, O. Kanie, K. F. Shortridge, T. Suzuki, D. Miyamoto, K. I. Hidari, C. H. Wong, Y. Suzuki, An O-glycoside of sialic acid derivative that inhibits both hemagglutinin and sialidase activities of influenza viruses, Glycobiology, vol. 12, 183-190, 2002
|
| 2002 |
J. Liu, C. Y. Huang, C. H. Wong, An efficient method for the preparation of 2-hydroxy- and 2-aminoglycals from glycosyl sulfoxides, Tetrahedron Lett, vol. 43, 3447-3448, 2002
|
| 2002 |
J. Liu, C. H. Wong, An efficient method for the cleavage of p-methoxybenzylidene (PMP), tetrahydropyranyl (THP) and 1,3-dithiane protecting groups by Selectfluor(TM), Tetrahedron Lett, vol. 43, 4037-4039, 2002
|
| 2002 |
J. J. Liu, C. H. Wong, Aldolase-catalyzed asymmetric synthesis of novel pyranose synthons as a new entry to heterocycles and epothilones, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 41, 1404-1407, 2002
|
| 2002 |
Z. Y. Zhang, K. Niikura, X. F. Huang, C. H. Wong, A strategy for the one-pot synthesis of sialylated oligosaccharides, CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, vol. 80, 1051-1054, 2002
|
| 2002 |
A. Brik, Y. C. Lin, J. Elder, C. H. Wong, A quick diversity-oriented amide-forming reaction to optimize P-subsite residues of HIV protease inhibitors, Chem Biol, vol. 9, 891-896, 2002
|
| 2002 |
E. Chapman, S. Ding, P. G. Schultz, C. H. Wong, A potent and highly selective sulfotransferase inhibitor, J Am Chem Soc, vol. 124, 14524-14525, 2002
|
| 2002 |
E. Chapman, C. H. Wong, A pH sensitive colorometric assay for the high-throughput screening of enzyme inhibitors and substrates: a case study using kinases, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 10, 551-555, 2002
|
| 2001 |
B. Buhler, Y. C. Lin, G. Morris, A. J. Olson, C. H. Wong, D. D. Richman, J. H. Elder, B. E. Torbett, Viral evolution in response to the broad-based retroviral protease inhibitor TL-3, J Virol, vol. 75, 9502-9508, 2001
|
| 2001 |
P. Sears, C. H. Wong, Toward automated synthesis of oligosaccharides and glycoproteins, Science, vol. 291, 2344-2350, 2001
|
| 2001 |
C. S. Yu, K. Niikura, C. C. Lin, C. H. Wong, The Thioglycoside and Glycosyl Phosphite of 5-Azido Sialic Acid: Excellent Donors for the alpha-Glycosylation of Primary Hydroxy Groups This research was supported by Academia Sinica (Taipei) and the NIH (USA), ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 40, 2900-2903, 2001
|
| 2001 |
F. Burkhart, Z. Y. Zhang, S. Wacowich Sgarbi, C. H. Wong, Synthesis of the Globo H hexasaccharide using the programmable reactivity-based one-pot strategy ( This research was supported by the National Institutes of Health. F.B. thanks the Deutsche Forschungsgemeinschaft for a fellowship), ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 40, 1274-1277, 2001
|
| 2001 |
I. A. Kozlov, S. Mao, Y. Xu, X. Huang, L. Lee, P. S. Sears, C. Gao, A. R. Coyle, K. D. Janda, C. H. Wong, Synthesis of solid-supported mirror-image sugars: a novel method for selecting receptors for cellular-surface carbohydrates, Chembiochem, vol. 2, 741-746, 2001
|
| 2001 |
T. K. Ritter, C. H. Wong, Synthesis of N-acetylglucosamine thiazoline/lipid II hybrids, Tetrahedron Lett, vol. 42, 615-618, 2001
|
| 2001 |
V. D. Le, C. C. Mak, Y. C. Lin, J. H. Elder, C. H. Wong, Structure-activity studies of FIV and HIV protease inhibitors containing allophenylnorstatine, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 9, 1185-1195, 2001
|
| 2001 |
C. H. Wong, Y. Ichikawa, G. J. Shen, Production of fucosylated carbohydrates by enzymatic fucosylation; synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose, US Patent, vol. #6,319,695, 2001
|
| 2001 |
M. G. Silvestri, C. H. Wong, Opening of thiiranes: preparation of orthogonal protected 2-thioglyceraldehyde, J Org Chem, vol. 66, 910-914, 2001
|
| 2001 |
A. Heine, G. DeSantis, J. G. Luz, M. Mitchell, C. H. Wong, I. A. Wilson, Observation of covalent intermediates in an enzyme mechanism at atomic resolution, Science, vol. 294, 369-374, 2001
|
| 2001 |
M. Izumi, C. H. Wong, Microbial sialyltransferases for carbohydrate synthesis, TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY, vol. 13, 345-360, 2001
|
| 2001 |
M. Izumi, G. J. Shen, S. Wacowich Sgarbi, T. Nakatani, O. Plettenburg, C. H. Wong, Microbial glycosyltransferases for carbohydrate synthesis: alpha-2,3-sialyltransferase from Neisseria gonorrheae, J Am Chem Soc, vol. 123, 10909-10918, 2001
|
| 2001 |
C. H. Wong, Inhibition of human fucosyltransferases with N-linked Lewis-x and LacNAc analogs, US Patent, vol. #6,232,450, 2001
|
| 2001 |
X. F. Huang, K. L. Witte, D. E. Bergbreiter, C. H. Wong, Homogenous enzymatic synthesis using a thermo-responsive water-soluble polymer support, Adv Synth Catal, vol. 343, 675-681, 2001
|
| 2001 |
J. Liu, A. R. Shikhman, M. K. Lotz, C. H. Wong, Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis, Chem Biol, vol. 8, 701-711, 2001
|
| 2001 |
K. M. Koeller, C. H. Wong, Enzymes for chemical synthesis, Nature, vol. 409, 232-240, 2001
|
| 2001 |
C. H. Wong, M. D. Burkart, Enzymatic sulfation of biomolecules, US Patent, vol. # 6,255,088, 2001
|
| 2001 |
C. H. Wong, Editorial commentary, Adv Synth Catal, vol. 343, 495-495, 2001
|
| 2001 |
C. C. Mak, V. D. Le, Y. C. Lin, J. H. Elder, C. H. Wong, Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residue, Bioorg Med Chem Lett, vol. 11, 219-222, 2001
|
| 2001 |
X. S. Ye, X. F. Huang, C. H. Wong, Conversion of the carboxy group of sialic acid donors to a protected hydroxymethyl group yields an efficient reagent for the synthesis of the unnatural beta-linkage, Chem Commun, vol. 11, 974-975, 2001
|
| 2001 |
C. Saotome, C. H. Wong, O. Kanie, Combinatorial library of five-membered iminocyclitol and the inhibitory activities against glyco-enzymes, Chem Biol, vol. 8, 1061-1070, 2001
|
| 2001 |
M. Mitchell, L. Qaio, C. H. Wong, Chemical-enzymatic synthesis of iminocyclitol phosphonic acids, Adv Synth Catal, vol. 343, 596-599, 2001
|
| 2001 |
T. K. Ritter, C. H. Wong, Carbohydrate-Based Antibiotics: A New Approach to Tackling the Problem of Resistance, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 40, 3508-3533, 2001
|
| 2001 |
H. Liu, R. Sadamoto, P. S. Sears, C. H. Wong, An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl-peptides, J Am Chem Soc, vol. 123, 9916-9917, 2001
|
| 2000 |
K. M. Koeller, M. E. B. Smith, C. H. Wong, Tyrosine sulfation on a PSGL-1 glycopeptide influences the reactivity of glycosyltransferases responsible for synthesis of the attached O-glycan, J Am Chem Soc, vol. 122, 742-743, 2000
|
| 2000 |
T. D. Machajewski, C. H. Wong, The Catalytic Asymmetric Aldol Reaction, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 39, 1352-1375, 2000
|
| 2000 |
K. M. Koeller, C. H. Wong, Synthesis of complex carbohydrates and glycoconjugates: enzyme-based and programmable one-pot strategies, Chem Rev, vol. 100, 4465-4494, 2000
|
| 2000 |
V. D. Le, C. H. Wong, Synthesis of 2-substituted polyhydroxytetrahydropyrimidines (N-hydroxy cyclic guanidino-sugars): transition-state mimics of enzymatic glycosidic cleavage, J Org Chem, vol. 65, 2399-2409, 2000
|
| 2000 |
K. Shibata, K. Hiruma, O. Kanie, C. H. Wong, Synthesis of 1,1-linked galactosyl mannosides carrying a thiazine ring as mimetics of sialyl Lewis X antigen: investigation of the effect of carboxyl group orientation on P-selectin inhibition, J Org Chem, vol. 65, 2393-2398, 2000
|
| 2000 |
C. Saotome, Y. Kanie, O. Kanie, C. H. Wong, Synthesis and enzymatic evaluation of five-membered iminocyclitols and a pseudodisaccharide, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, 2249-2261, 2000
|
| 2000 |
X. L. Sun, Y. Kanie, C. T. Guo, O. Kanie, Y. Suzuki, C. H. Wong, Syntheses of C-3-modified sialylglycosides as selective inhibitors of influenza hemagglutinin and neuraminidase, Eur J Org Chem, vol. 2643-2653, 2000
|
| 2000 |
M. Li, G. M. Morris, T. Lee, G. S. Laco, C. H. Wong, A. J. Olson, J. H. Elder, A. Wlodawer, A. Gustchina, Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease, Proteins, vol. 38, 29-40, 2000
|
| 2000 |
S. J. Sucheck, C. H. Wong, RNA as a target for small molecules, Curr Opin Chem Biol, vol. 4, 678-686, 2000
|
| 2000 |
O. Kanie, G. Grotenbreg, C. H. Wong, Removal of Benzyl Protecting Groups from Solid-Supported Compounds by Hydrogenolysis Using Palladium Nanoparticles, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 39, 4545-4547, 2000
|
| 2000 |
M. D. Burkart, M. Izumi, E. Chapman, C. H. Lin, C. H. Wong, Regeneration of PAPS for the enzymatic synthesis of sulfated oligosaccharides, J Org Chem, vol. 65, 5565-5574, 2000
|
| 2000 |
K. M. Koeller, C. H. Wong, Recycling of sugar nucleotides in enzymatic glycosylation, In: Carbohydrates in Chemistry and Biology, vol. 663-684, 2000
|
| 2000 |
T. L. Sheppard, C. H. Wong, G. F. Joyce, Nucleoglycoconjugates: design and synthesis of a new class of DNA-carbohydrate conjugates, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 39, 3660-3663, 2000
|
| 2000 |
C. H. Wong, M. Hendrix, P. Alper, S. Priestley, Nucleic acid binders having an hydroxyamine motif, US Patent, vol. #6,120,997, 2000
|
| 2000 |
C. H. Wong, Method for synthesizing 2-ketoaldonic acids, US Patent, vol. #6,080,563, 2000
|
| 2000 |
C. H. Wong, C. H. Lin, Ketoaldonic acids having formed stereogenic centers of R configuration: Methods and Compositions, US Patent, vol. #6,353,095, 2000
|
| 2000 |
T. J. Tolbert, C. H. Wong, Intein-mediated synthesis of proteins containing carbohydrates and other molecular probes, J Am Chem Soc, vol. 122, 5421-5428, 2000
|
| 2000 |
Z. Zhang, C. H. Wong, Glycosylation methods: use of phosphites, In: Carbohydrates in Chemistry and Biology, vol. 117-134, 2000
|
| 2000 |
K. D. Kreutter, C. H. Wong, Enzyme inhibitors, In: Stimulating Concepts in Chemistry, vol. 356-368, 2000
|
| 2000 |
K. M. Koeller, C. H. Wong, Emerging themes in medicinal glycoscience, Nat Biotechnol, vol. 18, 835-841, 2000
|
| 2000 |
T. Flessner, C. H. Wong, Efficient synthesis of triazoles from -arabinose and -fucose, Tetrahedron Lett, vol. 41, 7805-7808, 2000
|
| 2000 |
S. Fong, T. D. Machajewski, C. C. Mak, C. H. Wong, Directed evolution of D-2-keto-3-deoxy-6-phosphogluconate aldolase to new variants for the efficient synthesis of D- and L-sugars, Chem Biol, vol. 7, 873-883, 2000
|
| 2000 |
S. J. Sucheck, W. A. Greenberg, T. J. Tolbert, C. H. Wong, Design of Small Molecules That Recognize RNA: Development of Aminoglycosides as Potential Antitumor Agents That Target Oncogenic RNA Sequences, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 39, 1080-1084, 2000
|
| 2000 |
S. J. Sucheck, A. L. Wong, K. M. Koeller, D. D. Boehr, K. Draker, P. Sears, G. D. Wright, C. H. Wong, Design of bifunctional antibiotics that target bacterial rRNA and inhibit resistance-causing enzymes, J Am Chem Soc, vol. 122, 5230-5231, 2000
|
| 2000 |
C. Y. Tsai, X. Huang, C. H. Wong, Design and synthesis of cyclic sialyl Lewis X mimetics: a remarkable enhancement of inhibition by pre-organizing all essential functional groups, Tetrahedron Lett, vol. 41, 9499-9503, 2000
|
| 2000 |
K. M. Koeller, C. H. Wong, Complex carbohydrate synthesis tools for glycobiologists: enzyme-based approach and programmable one-pot strategies, Glycobiology, vol. 10, 1157-1169, 2000
|
| 2000 |
K. M. Koeller, C. H. Wong, Chemoenzymatic synthesis of sialyl-trimeric-Lewis x, CHEMISTRY-A EUROPEAN JOURNAL, vol. 6, 1243-1251, 2000
|
| 2000 |
K. M. Koeller, M. E. Smith, C. H. Wong, Chemoenzymatic synthesis of PSGL-1 glycopeptides: sulfation on tyrosine affects glycosyltransferase-catalyzed synthesis of the O-glycan, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, 1017-1025, 2000
|
| 2000 |
A. Duffels, L. G. Green, R. Lenz, S. V. Ley, S. P. Vincent, C. H. Wong, Chemoenzymatic synthesis of L-galactosylated dimeric sialyl Lewis X structures employing alpha-1,3-fucosyltransferase V, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, 2519-2525, 2000
|
| 2000 |
K. M. Koeller, M. E. B. Smith, R. F. Huang, C. H. Wong, Chemoenzymatic synthesis of a PSGL-1 N-terminal glycopeptide containing tyrosine sulfate and alpha-O-linked sialyl Lewis X, J Am Chem Soc, vol. 122, 4241-4242, 2000
|
| 2000 |
V. Wittmann, A. K. Datta, K. M. Koeller, C. H. Wong, Chemoenzymatic synthesis and fluorescent visualization of cell-surface selectin-bound sialyl Lewis x derivatives, CHEMISTRY-A EUROPEAN JOURNAL, vol. 6, 162-171, 2000
|
| 2000 |
A. Romero, C. H. Wong, Chemo-enzymatic total synthesis of 3-epiaustraline, australine, and 7-epialexine, J Org Chem, vol. 65, 8264-8268, 2000
|
| 2000 |
M. D. Burkart, S. P. Vincent, A. Duffels, B. W. Murray, S. V. Ley, C. H. Wong, Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic probes for glycosyltransferases, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, 1937-1946, 2000
|
| 2000 |
S. P. Vincent, A. Schleyer, C. H. Wong, Asymmetric Strecker synthesis of C-glycopeptide, J Org Chem, vol. 65, 4440-4443, 2000
|
| 2000 |
X. S. Ye, C. H. Wong, Anomeric reactivity-based one-pot oligosaccharide synthesis: a rapid route to oligosaccharide libraries, J Org Chem, vol. 65, 2410-2431, 2000
|
| 2000 |
Y. C. Lin, Z. Beck, T. Lee, V. D. Le, G. M. Morris, A. J. Olson, C. H. Wong, J. H. Elder, Alteration of substrate and inhibitor specificity of feline immunodeficiency virus protease, J Virol, vol. 74, 4710-4720, 2000
|
| 2000 |
M. Takayanagi, T. Flessner, C. H. Wong, A strategy for the solution-phase parallel synthesis of N-(pyrrolidinylmethyl)hydroxamic acids, J Org Chem, vol. 65, 3811-3815, 2000
|
| 1999 |
X. Zhang, P. B. Rosenthal, F. Formanowski, W. Fitz, C. H. Wong, H. Meier Ewert, J. J. Skehel, D. C. Wiley, X-ray crystallographic determination of the structure of the influenza C virus haemagglutinin-esterase-fusion glycoprotein, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 55, 945-961, 1999
|
| 1999 |
C. H. Wong, T. Kimura, Transglycosylation reactions employing a-galactosidase, US Patent, vol. #5,876,981, 1999
|
| 1999 |
P. Sears, K. Witte, C. H. Wong, The effect of counterion, water concentration, and stirring on the stability of subtilisin BPN ' in organic solvents, Journal of Molecular Catalysis B-Enzymatic, vol. 6, 297-304, 1999
|
| 1999 |
C. C. Lin, F. Moris-Varas, G. Weitz-Schmidt, C. H. Wong, Synthesis of sialyl Lewis x mimetics as selectin inhibitors by enzymatic aldol condensation reactions, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 7, 425-433, 1999
|
| 1999 |
D. Depre, A. Duffels, L. G. Green, R. Lenz, S. V. Ley, C. H. Wong, Synthesis of glycans from the glycodelins: Two undeca-, two deca-, three nona-, an octa- and a heptasaccharide, CHEMISTRY-A EUROPEAN JOURNAL, vol. 5, 3326-3340, 1999
|
| 1999 |
K. M. Koeller, C. H. Wong, Synthesis of biologically active glycopeptides, J Chin Chem Soc, vol. 46, 659-686, 1999
|
| 1999 |
H. Yuasa, H. Hashimoto, Y. Abe, T. Kajimoto, C. H. Wong, Studies on the unusual stability of cis-2,5-diethoxy-2,5-bis(hydroxymethyl)-1,4-dioxane, Tetrahedron, vol. 55, 2193-2204, 1999
|
| 1999 |
W. G. Wu, L. Pasternack, D. H. Huang, K. M. Koeller, C. C. Lin, O. Seitz, C. H. Wong, Structural study on O-glycopeptides: Glycosylation-induced conformational changes of O-GlcNAc, O-LacNAc, O-sialyl-LacNAc, and O-sialyl-lewis-X peptides of the mucin domain of MAdCAM-1, J Am Chem Soc, vol. 121, 2409-2417, 1999
|
| 1999 |
C. H. Wong, C. C. Lin, T. Kajimoto, Sialyl Lewis x mimetics incorporating fucopeptides, US Patent, vol. #5,962,660, 1999
|
| 1999 |
S. Takayama, S. J. Chung, Y. Igarashi, Y. Ichikawa, A. Sepp, R. I. Lechler, J. Wu, T. Hayashi, G. Siuzdak, C. H. Wong, Selective inhibition of beta-1,4- and alpha-1,3-galactosyltransferases: donor sugar-nucleotide based approach, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 7, 401-409, 1999
|
| 1999 |
G. Weitz Schmidt, K. W. Gong, C. H. Wong, Selectin/glycoconjugate binding assays for the identification and optimization of selectin antagonists, Anal Biochem, vol. 273, 81-88, 1999
|
| 1999 |
Z. Y. Zhang, I. R. Ollmann, X. S. Ye, R. Wischnat, T. Baasov, C. H. Wong, Programmable one-pot oligosaccharide synthesis, J Am Chem Soc, vol. 121, 734-753, 1999
|
| 1999 |
S. Mao, C. Gao, C. H. Lo, P. Wirsching, C. H. Wong, K. D. Janda, Phage-display library selection of high-affinity human single-chain antibodies to tumor-associated carbohydrate antigens sialyl Lewisx and Lewisx, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 96, 6953-6958, 1999
|
| 1999 |
C. H. Wong, C. H. Lin, G. J. Shen, One-pot enzymatic sulfation process using 3?-phosphoadenosine-5?-phosphosulfate and recycled phosphorylated adenosine intermediates, US Patent, vol. #5,919,673, 1999
|
| 1999 |
C. H. Wong, Y. Ichikawa, Oligosaccharide enzyme substrates and inhibitors: Methods and composition, Canadian Patent, vol. #2,106,301, 1999
|
| 1999 |
C. H. Wong, Mimics of complex carbohydrates recognized by receptors, Accounts Chem Res, vol. 32, 376-385, 1999
|
| 1999 |
C. H. Wong, C. C. Lin, T. Woltering, Liposomic sialyl Lewis X mimetics, US Patent, vol. (Allowed), 1999
|
| 1999 |
R.A. Lerner, C. H. Wong, D. L. Boger, S. J. Henriksen, Inhibitors of oleamide hydrolase, US Patent, vol. #5,856,537, 1999
|
| 1999 |
T. Lee, J.H. Elder, C. H. Wong, HIV protease inhibitors with small P3 residues. Broad-based Protease Inhibitors Efficacious Against FIV, SIV, US Patent, vol. (Allowed), 1999
|
| 1999 |
C. H. Wong, D. Slee, K. Laslo, HIV protease inhibitors, US Patent, vol. (Allowed), 1999
|
| 1999 |
S. Hiranuma, O. Kanie, C. H. Wong, Formation of the 1,2,6-orthoester of mannose and its utilization in the glycosylation reaction, Tetrahedron Lett, vol. 40, 6423-6426, 1999
|
| 1999 |
G. J. Shen, A. K. Datta, M. Izumi, K. M. Koeller, C. H. Wong, Expression of alpha2,8/2,9-polysialyltransferase from Escherichia coli K92. Characterization of the enzyme and its reaction products, J Biol Chem, vol. 274, 35139-35146, 1999
|
| 1999 |
M. Hendrix, C. H. Wong, Enzymatic synthesis of carbohydrates, In: Bioorganic Chemistry: Carbohydrates, vol. 198-243, 1999
|
| 1999 |
M. D. Burkart, M. Izumi, C. H. Wong, Enzymatic Regeneration of 3'-Phosphoadenosine-5'-Phosphosulfate Using Aryl Sulfotransferase for the Preparative Enzymatic Synthesis of Sulfated Carbohydrates, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 38, 2747-2750, 1999
|
| 1999 |
C. H. Wong, S. Takayama, B. Orsat, W. Moree, Enantioselective enzymatic protection of amines, US Patent, vol. #5,981,267, 1999
|
| 1999 |
S. P. Vincent, M. D. Burkart, C. Y. Tsai, Z. Y. Zhang, C. H. Wong, Electrophilic fluorination-nucleophilic addition reaction mediated by Selectfluor: Mechanistic studies and new applications, J Org Chem, vol. 64, 5264-5279, 1999
|
| 1999 |
T. Y. Lee, V. D. Le, D. Y. Lim, Y. C. Lin, G. M. Morris, A. L. Wong, A. J. Olson, J. H. Elder, C. H. Wong, Development of a new type of protease inhibitors, efficacious against FIV and HIV variants, J Am Chem Soc, vol. 121, 1145-1155, 1999
|
| 1999 |
S. Takayama, S. T. Lee, S. C. Hung, C. H. Wong, Designing enzymatic resolution of amines, Chem Commun, vol. 2, 127-128, 1999
|
| 1999 |
C. M. Huwe, T. J. Woltering, J. Jiricek, G. Weitz-Schmidt, C. H. Wong, Design, synthesis and biological evaluation of aryl-substituted sialyl Lewis X mimetics prepared via cross-metathesis of C-fucopeptides, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 7, 773-788, 1999
|
| 1999 |
W. A. Greenberg, E. S. Priestley, P. S. Sears, P. B. Alper, C. Rosenbohm, M. Hendrix, S. C. Hung, C. H. Wong, Design and synthesis of new aminoglycoside antibiotics containing neamine as an optimal core structure: Correlation of antibiotic activity with in vitro inhibition of translation, J Am Chem Soc, vol. 121, 6527-6541, 1999
|
| 1999 |
C. H. Wong, Design and synthesis of carbohydrate mimetics: A new strategy for tackling the problem of carbohydrate-mediated biological recognition, J Chin Chem Soc, vol. 46, 271-281, 1999
|
| 1999 |
M. Famulok, E. L. Winnacker, C. H. Wong, Combinatorial Chemistry in Biology, Current Topics in Microbiology and Immunology, vol. 243, 1999
|
| 1999 |
T. D. Machajewski, C. H. Wong, Chemoenzymatic synthesis of key epothilone fragments, Synthesis, vol. Suppl 1, 1469-1472, 1999
|
| 1999 |
B. Cornils, W. A. Herrmann, R. Schlogl, C. H. Wong, Catalysis from A to Z-A Concise Encyclopedia, In: Wiley-VCH, Weinheim, Germany, 1999
|
| 1999 |
P. Sears, C. H. Wong, Carbohydrate Mimetics: A New Strategy for Tackling the Problem of Carbohydrate-Mediated Biological Recognition, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 38, 2300-2324, 1999
|
| 1999 |
R. D. Kidd, P. Sears, D. H. Huang, K. Witte, C. H. Wong, G. K. Farber, Breaking the low barrier hydrogen bond in a serine protease, Protein Sci, vol. 8, 410-417, 1999
|
| 1999 |
C. H. Wong, T. Sugai, G. J. Shen, Biologically pur culture of Aureobacterium barkeri: KDO-37-2, US Patent, vol. # 5,869,316, 1999
|
| 1999 |
M. D. Burkart, S. P. Vincent, C. H. Wong, An efficient synthesis of CMP-3-fluoroneuraminic acid, Chem Commun, vol. 16, 1525-1526, 1999
|
| 1999 |
M. Takebayashi, S. Hiranuma, Y. Kanie, T. Kajimoto, O. Kanie, C. H. Wong, A versatile synthetic strategy for the preparation and discovery of new iminocyclitols as inhibitors of glycosidases, J Org Chem, vol. 64, 5280-5291, 1999
|
| 1999 |
M. D. Burkart, C. H. Wong, A continuous assay for the spectrophotometric analysis of sulfotransferases using aryl sulfotransferase IV, Anal Biochem, vol. 274, 131-137, 1999
|
| 1998 |
C. H. Wong, H.J.M. Gijsen, Use of 2-deoxyribose-5-phosphate aldolase to prepare 2-deoxyfucose, analogues and derivatives, US Patent, vol. #5,795,749, 1998
|
| 1998 |
R. Martin, K. L. Witte, C. H. Wong, The synthesis and enzymatic incorporation of sialic acid derivatives for use as tools to study the structure, activity, and inhibition of glycoproteins and other glycoconjugates, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 6, 1283-1292, 1998
|
| 1998 |
C. T. Guo, C. H. Wong, T. Kajimoto, T. Miura, Y. Ida, L. R. Juneja, M. J. Kim, H. Masuda, T. Suzuki, Y. Suzuki, Synthetic sialylphosphatidylethanolamine derivatives bind to human influenza A viruses and inhibit viral infection, GLYCOCONJUGATE JOURNAL, vol. 15, 1099-1108, 1998
|
| 1998 |
C. Y. Tsai, W. K. Park, G. Weitz-Schmidt, B. Ernst, C. H. Wong, Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction, Bioorg Med Chem Lett, vol. 8, 2333-2338, 1998
|
| 1998 |
K. Hiruma, O. Kanie, C. H. Wong, Synthesis of analogs of 1,1-linked galactosyl mannoside as mimetics of sialyl Lewis X tetrasaccharide, Tetrahedron, vol. 54, 15781-15792, 1998
|
| 1998 |
R. Wischnat, R. Martin, C. H. Wong, Synthesis of a new class of N-linked Lewis and LacNAc analogues as potential inhibitors of human fucosyltransferases: A general method for the incorporation of an iminocyclitol as a transition-state mimetic of the donor sugar to the acceptor, J Org Chem, vol. 63, 8361-8365, 1998
|
| 1998 |
C. H. Wong, S. Takayama, Synthesis of 9-0-acetyl N-acetyl-neuraminic acid oligosaccharides, US Patent, vol. #5,766,887, 1998
|
| 1998 |
T. Miura, T. Kajimoto, M. Jimbo, K. Yamagishi, J. C. Inokuchi, C. H. Wong, Synthesis and evaluation of morpholino- and pyrrolidinosphingolipids as inhibitors of glucosylceramide synthase, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 6, 1481-1489, 1998
|
| 1998 |
P. B. Rosenthal, X. Zhang, F. Formanowski, W. Fitz, C. H. Wong, H. Meier Ewert, J. J. Skehel, D. C. Wiley, Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus, Nature, vol. 396, 92-96, 1998
|
| 1998 |
C. H. Wong, M. Hendrix, E. S. Priestley, W. A. Greenberg, Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA, Chem Biol, vol. 5, 397-406, 1998
|
| 1998 |
K. Witte, O. Seitz, C. H. Wong, Solution- and solid-phase synthesis of N-protected glycopeptide esters of the benzyl type as substrates for subtilisin-catalyzed glycopeptide couplings, J Am Chem Soc, vol. 120, 1979-1989, 1998
|
| 1998 |
C. H. Wong, T. G. Marron, T. J. Woltering, G. WeitzSchmidt, Sialyl Lewis x mimetics incorporating mannopeptides, US Patent, vol. #5,837,862, 1998
|
| 1998 |
E. E. Simanek, G. J. McGarvey, J. A. Jablonowski, C. H. Wong, Selectin−Carbohydrate Interactions: From Natural Ligands to Designed Mimics, Chem Rev, vol. 98, 833-862, 1998
|
| 1998 |
T. Kanemitsu, O. Kanie, C. H. Wong, Quantitative monitoring of solid-phase synthesis using gated decoupling C-13 NMR spectroscopy with a C-13-enriched protecting group and an internal standard in the synthesis of sialyl Lewis(X) tetrasaccharide, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 37, 3415-3418, 1998
|
| 1998 |
C. H. Wong, T. Hayashi, Process for preparing nucleoside inhibitors of glycosyltransferases, US Patent, vol. #5,770,407, 1998
|
| 1998 |
P. B. Alper, M. Hendrix, P. Sears, C. H. Wong, Probing the specificity of aminoglycoside ribosomal RNA interactions with designed synthetic analogs, J Am Chem Soc, vol. 120, 1965-1978, 1998
|
| 1998 |
J. H. Hogg, I. R. Ollmann, A. Wetterholm, M. B. Andberg, J. Haeggstrom, B. Samuelsson, C. H. Wong, Probing the activities and mechanisms of leukotriene A(4) hydrolase with synthetic inhibitors, CHEMISTRY-A EUROPEAN JOURNAL, vol. 4, 1698-1713, 1998
|
| 1998 |
T. F. J. Lampe, G. Weitz-Schmidt, C. H. Wong, Parallel Synthesis of Sialyl Lewis X Mimetics on a Solid Phase: Access to a Library of Fucopeptides, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 37, 1707-1711, 1998
|
| 1998 |
C. H. Wong, Method for synthesizing 2-ketoaldonic acids, US Patent, vol. #5,759,825, 1998
|
| 1998 |
P. Sears, C. H. Wong, Mechanism-based inhibition of carbohydrate-mediated biological recognitions, Chem Commun, vol. 11, 1161-1170, 1998
|
| 1998 |
V. Wittmann, S. Takayama, K. W. Gong, G. Weitz-Schmidt, C. H. Wong, Ligand recognition by E- and P-selectin: Chemoenzymatic synthesis and inhibitory activity of bivalent sialyl Lewis x derivatives and sialyl Lewis x carboxylic acids, J Org Chem, vol. 63, 5137-5143, 1998
|
| 1998 |
C. H. Wong, F. MorisVaras, C. C. Lin, Inhibitors of E-, P-, and L-selectin binding, US Patent, vol. #5,830,871, 1998
|
| 1998 |
E. E. Simanek, D. H. Huang, L. Pasternack, T. D. Machajewski, O. Seitz, D. S. Millar, H. J. Dyson, C. H. Wong, Glycosylation of threonine of the repeating unit of RNA polymerase II with beta-linked N-acetylglucosame leads to a turnlike structure, J Am Chem Soc, vol. 120, 11567-11575, 1998
|
| 1998 |
C. H. Wong, H. Kondo, Glycosylation of peptides using glycosyl phosphite reagents, US Patent, vol. #5,854,391, 1998
|
| 1998 |
P. Sears, C. H. Wong, Enzyme action in glycoprotein synthesis, Cell Mol Life Sci, vol. 54, 223-252, 1998
|
| 1998 |
V. P. Vassilev, E. E. Simanek, M. R. Wood, C. H. Wong, Enzymatic synthesis of a chiral gelator with remarkably low molecular weight, Chem Commun, vol. 17, 1865-1866, 1998
|
| 1998 |
Y. Kanie, A. Kirsch, O. Kanie, C. H. Wong, Enzymatic assay of galactosyltransferase by capillary electrophoresis, Anal Biochem, vol. 263, 240-245, 1998
|
| 1998 |
R. Wischnat, R. Martin, S. Takayama, C. H. Wong, Chemoenzymatic synthesis of iminocyclitol derivatives: a useful library strategy for the development of selective fucosyltransfer enzymes inhibitors, Bioorg Med Chem Lett, vol. 8, 3353-3358, 1998
|
| 1998 |
J. B. Jones, C. H. Wong, Biocatalysis and biotransformation exploiting nature's magic - Overview, Curr Opin Chem Biol, vol. 2, 67-69, 1998
|
| 1998 |
C. H. Wong, X. S. Ye, Z. Y. Zhang, Assembly of oligosaccharide libraries with a designed building block and an efficient orthogonal protection-deprotection strategy, J Am Chem Soc, vol. 120(28), 7137-7138, 1998
|
| 1998 |
T. Lee, G. S. Laco, B. E. Torbett, H. S. Fox, D. L. Lerner, J. H. Elder, C. H. Wong, Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 95, 939-944, 1998
|
| 1998 |
S. J. Chung, S. Takayama, C. H. Wong, Acceptor substrate-based selective inhibition of galactosyltransferases, Bioorg Med Chem Lett, vol. 8, 3359-3364, 1998
|
| 1998 |
K. Witte, J. Skolnick, C. H. Wong, A synthetic retrotransition (backward reading) sequence of the right-handed three-helix bundle domain (10-53) of protein A shows similarity in conformation as predicted by computation, J Am Chem Soc, vol. 120, 13042-13045, 1998
|
| 1998 |
H. Kamitakahara, T. Suzuki, N. Nishigori, Y. Suzuki, O. Kanie, C. H. Wong, A lysoganglioside poly-L-glutamic acid conjugate as a picomolar inhibitor of influenza hemagglutinin, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 37, 1524-1528, 1998
|
| 1998 |
C. H. Wong, M. Hendrix, D. D. Manning, C. Rosenbohm, W. A. Greenberg, A library approach to the discovery of small molecules that recognize RNA: Use of a 1,3-hydroxyamine motif as core, J Am Chem Soc, vol. 120, 8319-8327, 1998
|
| 1997 |
C. H. Lin, B. W. Murray, I. R. Ollmann, C. H. Wong, Why is CMP-ketodeoxyoctonate highly unstable?, Biochemistry, vol. 36, 780-785, 1997
|
| 1997 |
M. Kaneko, O. Kanie, T. Kajimoto, C. H. Wong, Toward a transition state analog inhibitor of N-acetylglucosaminyl transferase V, Bioorg Med Chem Lett, vol. 7, 2809-2812, 1997
|
| 1997 |
M. W. Cappi, W. J. Moree, L. Qiao, T. G. Marron, G. Weitz-Schmidt, C. H. Wong, Synthesis of novel 6-amido-6-deoxy-l-galactose derivatives as sialyl Lewis X mimetics, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 5, 283-296, 1997
|
| 1997 |
M. Koketsu, T. Nitoda, H. Sugino, L. R. Juneja, M. Kim, T. Yamamoto, N. Abe, T. Kajimoto, C. H. Wong, Synthesis of a novel sialic acid derivative (sialylphospholipid) as an antirotaviral agent, J Med Chem, vol. 40, 3332-3335, 1997
|
| 1997 |
C. H. Wong, F. MorisVara, S. C. Hung, T. G. Marron, C. C. Lin, K. W. Gong, G. WeitzSchmidt, Small molecules as structural and functional mimics of sialyl Lewis X tetrasaccharide in selectin inhibition: A remarkable enhancement of inhibition by additional negative charge and/or hydrophobic group, J Am Chem Soc, vol. 119, 8152-8158, 1997
|
| 1997 |
C. H. Wong, Sialyl Lewis x mimetics incorporating fucopeptides, US Patent, vol. #5,614,615, 1997
|
| 1997 |
C. H. Wong, T. Kajimoto, Sialyl Lewis X mimetics, US Patent, vol. #5,599,915, 1997
|
| 1997 |
C. C. Lin, C. H. Lin, C. H. Wong, Sialic acid aldolase-catalyzed condensation of pyruvate and N-substituted mannosamine: A useful method for the synthesis of N-substituted sialic acids, Tetrahedron Lett, vol. 38, 2649-2652, 1997
|
| 1997 |
J. Wu, S. Takayama, C. H. Wong, G. Siuzdak, Quantitative electrospray mass spectrometry for the rapid assay of enzyme inhibitors, Chem Biol, vol. 4, 653-657, 1997
|
| 1997 |
S. C. Hung, C. C. Lin, C. H. Wong, One-pot synthesis of 1-allyl- and 1-allenyl-6-O-acetyl-2,3,4-tri-O-benzyl-[alpha]-D-glycosides from methyl tetra-O-benzyl-[alpha]-D-glycosides, Tetrahedron Lett, vol. 38, 5419-5422, 1997
|
| 1997 |
C. H. Wong, T. Kajimoto, K.C. Liu, L. Chen, Omega-deoxy-azasugars, US Patent, vol. #5,596,005, 1997
|
| 1997 |
W. Fitz, C. H. Wong, Oligosaccharide synthesis by enzymatic glycosidation, In: Preparative Carbohydrate Chemistry, vol. 485-504, 1997
|
| 1997 |
C. H. Wong, Y. Ichikawa, G. J. Shen, Oligosaccharide enzyme substrates and inhibitors: methods and compositions, US Patent, vol. #5,593,887, 1997
|
| 1997 |
S. Takayama, G. J. McGarvey, C. H. Wong, Microbial aldolases and transketolases: new biocatalytic approaches to simple and complex sugars, Annu Rev Microbiol, vol. 51, 285-310, 1997
|
| 1997 |
B. W. Murray, V. Wittmann, M. D. Burkart, S. C. Hung, C. H. Wong, Mechanism of human alpha-1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack, Biochemistry, vol. 36, 823-831, 1997
|
| 1997 |
M. Hendrix, P. B. Alper, E. S. Priestley, C. H. Wong, Hydroxyamines as a new motif for the molecular recognition of phosphodiesters: Implications for aminoglycoside-RNA interactions, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 36, 95-98, 1997
|
| 1997 |
W. J. Moree, P. Sears, K. Kawashiro, K. Witte, C. H. Wong, Exploitation of subtilisin BPN' as catalyst for the synthesis of peptides containing noncoded amino acids, peptide mimetics and peptide conjugates, J Am Chem Soc, vol. 119, 3942-3947, 1997
|
| 1997 |
S. Takayama, G. J. McGarvey, C. H. Wong, Enzymes in organic synthesis: recent developments in aldol reactions and glycosylations, Chem Soc Rev, vol. 26, 407-415, 1997
|
| 1997 |
T. Kimura, V. P. Vassilev, G. J. Shen, C. H. Wong, Enzymatic synthesis of beta-hydroxy-alpha-amino acids based on recombinant D- and L-threonine aldolases, J Am Chem Soc, vol. 119, 11734-11742, 1997
|
| 1997 |
M. J. Kim, I. T. Lim, H. J. Kim, C. H. Wong, Enzymatic single aldol reactions of remote dialdehydes, Tetrahedron-Asymmetry, vol. 8, 1507-1509, 1997
|
| 1997 |
K. Witte, P. Sears, R. Martin, C. H. Wong, Enzymatic glycoprotein synthesis: Preparation of ribonuclease glycoforms via enzymatic glycopeptide condensation and glycosylation, J Am Chem Soc, vol. 119, 2114-2118, 1997
|
| 1997 |
M. Hendrix, E. S. Priestley, G. F. Joyce, C. H. Wong, Direct observation of aminoglycoside-RNA interactions by surface plasmon resonance, J Am Chem Soc, vol. 119, 3641-3648, 1997
|
| 1997 |
T. Ikeda, T. Kajimoto, H. Kondo, C. H. Wong, Design and synthesis of an alpha-mannosyl terpenoid as selective inhibitor of P-selectin, Bioorg Med Chem Lett, vol. 7, 2485-2490, 1997
|
| 1997 |
O. Seitz, C. H. Wong, Chemoenzymatic solution- and solid-phase synthesis of O-glycopeptides of the mucin domain of MAdCAM-1. A general route to O-LacNAc, O-sialyl-LacNAc, and O-sialyl-Lewis-X peptides, J Am Chem Soc, vol. 119, 8766-8776, 1997
|
| 1997 |
S. Takayama, R. Martin, J. Y. Wu, K. Laslo, G. Siuzdak, C. H. Wong, Chemoenzymatic preparation of novel cyclic imine sugars and rapid biological activity evaluation using electrospray mass spectrometry and kinetic analysis, J Am Chem Soc, vol. 119, 8146-8151, 1997
|
| 1997 |
S. Takayama, C. H. Wong, Chemo-enzymatic approach to carbohydrate recognition, Curr Org Chem, vol. 1, 109-126, 1997
|
| 1997 |
G. J. McGarvey, C. H. Wong, Chemical, enzymatic and structural studies in molecular glycobiology, LIEBIGS ANNALEN DER CHEMIE, vol. 6, 1059-1074, 1997
|
| 1997 |
K. D. Janda, L. C. Lo, C. H. Lo, M. M. Sim, R. Wang, C. H. Wong, R. A. Lerner, Chemical selection for catalysis in combinatorial antibody libraries, Science, vol. 275, 945-948, 1997
|
| 1997 |
C. H. Wong, H. Kondo, Carbon Linked Glycosyl Compounds, US Patent, vol. #5,597,906, 1997
|
| 1997 |
R. Wang, D. H. Steensma, Y. Takaoka, J. W. Yun, T. Kajimoto, C. H. Wong, A search for pyrophosphate mimics for the development of substrates and inhibitors of glycosyltransferases, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 5, 661-672, 1997
|
| 1997 |
M. D. Burkart, Z. Y. Zhang, S. C. Hung, C. H. Wong, A new method for the synthesis of fluoro-carbohydrates and glycosides using selectfluor, J Am Chem Soc, vol. 119, 11743-11746, 1997
|
| 1997 |
C. H. Wong, G. C. Look, A facile enzymatic synthesis of galactosyl-b-1,3-glycals, Australian Patent, vol. #672029, 1997
|
| 1997 |
T. Hayashi, B. W. Murray, R. Wang, C. H. Wong, A chemoenzymatic synthesis of UDP-(2-deoxy-2-fluoro)-galactose and evaluation of its interaction with galactosyltransferase, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 5, 497-500, 1997
|
| 1997 |
C. H. Wong, A chemo-enzymatic approach to the study of carbohydrate-based biological recognitions, Pure Appl Chem, vol. 69, 419-422, 1997
|
| 1997 |
V. Wittmann, C. H. Wong, 1H-Tetrazole as Catalyst in Phosphomorpholidate Coupling Reactions: Efficient Synthesis of GDP-Fucose, GDP-Mannose, and UDP-Galactose, J Org Chem, vol. 62, 2144-2147, 1997
|
| 1996 |
C. H. Wong, H. Kondo, Thio Linked Glycosyl Compounds, US Patent, vol. #5,514,784, 1996
|
| 1996 |
M. W. Cappi, W. J. Moree, L. Qiao, T. G. Marron, G. Weitz-Schmidt, C. H. Wong, The synthesis of novel 6-amino-6-deoxy-L-galactose glycopeptides as potent sialyl Lewis X mimetics, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 35, 2346-2347, 1996
|
| 1996 |
M. W. Cappi, W. J. Moree, L. Qiao, T. G. Marron, G. Weitz-Schmidt, C. H. Wong, The synthesis of novel 6-amido-6-deoxy-L-galactose derivatives as potent sialyl Lewis(x) mimetics, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 35, 2346-2348, 1996
|
| 1996 |
S. Takayama, P. O. Livingston, C. H. Wong, Synthesis of the melanoma-associated ganglioside 9-O-acetyl GD3 through regioselective enzymatic acetylation of GD3 using subtilisin, Tetrahedron Lett, vol. 37, 9271-9274, 1996
|
| 1996 |
R. Wang, C. H. Wong, Synthesis of sialyl Lewis X mimetics: Use of O-[alpha]-fucosyl-(1R, 2R)-2-aminocyclohexanol as core structure, Tetrahedron Lett, vol. 37, 5427-5430, 1996
|
| 1996 |
C. C. Lin, M. Shimazaki, M. P. Heck, S. Aoki, R. Wang, T. Kimura, H. Ritzen, S. Takayama, S. H. Wu, G. WeitzSchmidt, C. H. Wong, Synthesis of sialyl Lewis X mimetics and related structures using the glycosyl phosphite methodology and evaluation of E-selectin inhibition, J Am Chem Soc, vol. 118, 6826-6840, 1996
|
| 1996 |
S. Takayama, M. Shimazaki, L. Qiao, C. H. Wong, Synthesis of lactosamine derivatives using beta-D-galactosidase from Bacillus circulans, Bioorg Med Chem Lett, vol. 6, 1123-1126, 1996
|
| 1996 |
S. C. Hung, C. H. Wong, Synthesis of glycosyl chlorides with acid-labile protecting groups, Tetrahedron Lett, vol. 37, 4903-4906, 1996
|
| 1996 |
S. H. Wu, M. Shimazaki, C. C. Lin, L. Qiao, W. J. Moree, C. H. Wong, Synthesis of fucopeptides as sialyl Lewis X mimetics, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 35, 88-89, 1996
|
| 1996 |
X. H. Qian, F. MorisVaras, C. H. Wong, Synthesis of C-2-symmetrical polyhydroxyazepanes as inhibitors of glycosidases, Bioorg Med Chem Lett, vol. 6, 1117-1122, 1996
|
| 1996 |
W. Fitz, P. B. Rosenthal, C. H. Wong, Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 4, 1349-1353, 1996
|
| 1996 |
L. Qiao, B. W. Murray, M. Shimazaki, J. Schultz, C. H. Wong, Synergistic inhibition of human alpha-1,3-fucosyltransferase V, J Am Chem Soc, vol. 118, 7653-7662, 1996
|
| 1996 |
S. C. Hung, C. H. Wong, Samarium diiodide mediated coupling of glycosyl phosphates with carbon radical or anion acceptors - Synthesis of C-glycosides, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 35, 2671-2674, 1996
|
| 1996 |
H. J. Gijsen, L. Qiao, W. Fitz, C. H. Wong, Recent Advances in the Chemoenzymatic Synthesis of Carbohydrates and Carbohydrate Mimetics, Chem Rev, vol. 96, 443-474, 1996
|
| 1996 |
K. Hiruma, T. Kajimoto, G. WeitzSchmidt, I. Ollmann, C. H. Wong, Rational design and synthesis of a 1,1-linked disaccharide that is 5 times as active as sialyl Lewis X in binding to E-selectin, J Am Chem Soc, vol. 118, 9265-9270, 1996
|
| 1996 |
W. K. C. Park, M. Auer, H. Jaksche, C. H. Wong, Rapid combinatorial synthesis of aminoglycoside antibiotic mimetics: Use of a polyethylene glycol-linked amine and a neamine-derived aldehyde in multiple component condensation as a strategy for the discovery of new inhibitors of the HIV RNA Rev responsive element, J Am Chem Soc, vol. 118, 10150-10155, 1996
|
| 1996 |
C. H. Wong, Practical synthesis of oligosaccharides based on glycosyltransferases and glycosylphosphites, In: Modern Methods in Carbohydrate Synthesis, vol. 467-491, 1996
|
| 1996 |
C. De Luca, M. Lansing, F. Crescenzi, I. Martini, G. J. Shen, M. O'Regan, C. H. Wong, Overexpression, one-step purification and characterization of UDP-glucose dehydrogenase and UDP-N-acetylglucosamine pyrophosphorylase, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 4, 131-141, 1996
|
| 1996 |
C. H. Wong, Y. Ichikawa, Oligosaccharide enzyme substrates and inhibitors: Methods and composition, Australian Patent, vol. #668505, 1996
|
| 1996 |
C. H. Wong, N-Acetylgalactosaminyl or N-acetylglucosaminyl transfer using N-acetylglucosaminyl-1-phosphate or N-acetylgalactosaminyl-1-phosphate as precursor and glycosyl-nucleotide regeneration, US Patent, vol. # 5,516,665, 1996
|
| 1996 |
P. B. Alper, S. C. Hung, C. H. Wong, Metal catalyzed diazo transfer for the synthesis of azides from amines, Tetrahedron Lett, vol. 37, 6029-6032, 1996
|
| 1996 |
B. W. Murray, S. Takayama, J. Schultz, C. H. Wong, Mechanism and specificity of human alpha-1,3-fucosyltransferase V, Biochemistry, vol. 35, 11183-11195, 1996
|
| 1996 |
C. C. Lin, T. Kimura, S. H. Wu, G. WeitzSchmidt, C. H. Wong, Liposome-like fucopeptides as sialyl Lewis X mimetics, Bioorg Med Chem Lett, vol. 6, 2755-2760, 1996
|
| 1996 |
K. Shibata, K. Shingu, V. P. Vassiley, K. Nishide, T. Fujita, M. Node, T. Kajimoto, C. H. Wong, Kinetic and thermodynamic control of L-Threonine aldolase catalyzed reaction and its application to the synthesis of mycestericin D, Tetrahedron Lett, vol. 37, 2791-2794, 1996
|
| 1996 |
P. Sears, C. H. Wong, Intervention of carbohydrate recognition by proteins and nucleic acids, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 93, 12086-12093, 1996
|
| 1996 |
J. E. Patterson, I. R. Ollmann, B. F. Cravatt, D. L. Boger, C. H. Wong, R. A. Lerner, Inhibition of oleamide hydrolase catalyzed hydrolysis of the endogenous sleep-inducing lipid cis-9-octadecenamide, J Am Chem Soc, vol. 118, 5938-5945, 1996
|
| 1996 |
B. Orsat, P. B. Alper, W. Moree, C. P. Mak, C. H. Wong, Homocarbonates as substrates for the enantioselective enzymatic protection of amines, J Am Chem Soc, vol. 118, 712-713, 1996
|
| 1996 |
F. MorisVaras, X. H. Qian, C. H. Wong, Enzymatic/chemical synthesis and biological evaluation of seven-membered iminocyclitols, J Am Chem Soc, vol. 118, 7647-7652, 1996
|
| 1996 |
S. Takayama, W. J. Moree, C. H. Wong, Enzymatic resolution of amines and amino alcohols using pent-4-enoyl derivatives, Tetrahedron Lett, vol. 37, 6287-6290, 1996
|
| 1996 |
P. Sears, C. H. Wong, Engineering enzymes for bioorganic synthesis: Peptide bond formation, BIOTECHNOLOGY PROGRESS, vol. 12, 423-433, 1996
|
| 1996 |
C. H. Wong, Y. F. Wang, W. J. Hennen, Enantio- and regio-selective synthesis of organic compounds using enol esters as irreversible transacylation reagents, US Patent, vol. #5,585,252, 1996
|
| 1996 |
T. Uchiyama, T. J. Woltering, W. Wong, C. C. Lin, T. Kajimoto, M. Takebayashi, G. Weitz Schmidt, T. Asakura, M. Noda, C. H. Wong, Design and synthesis of C-linked fucosides as inhibitors of E-selectin, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 4, 1149-1165, 1996
|
| 1996 |
J. H. Jeong, B. W. Murray, S. Takayama, C. H. Wong, Cyclic guanidino-sugars with low pK(a) as transition-state analog inhibitors of glycosidases: Neutral instead of charged species are the active forms, J Am Chem Soc, vol. 118, 4227-4234, 1996
|
| 1996 |
C. H. Wong, Chemoenzymatic synthesis: Application to the study of carbohydrate recognition, ACTA CHEMICA SCANDINAVICA, vol. 50, 211-218, 1996
|
| 1996 |
X. Qian, F. Moris Varas, M. C. Fitzgerald, C. H. Wong, C2-symmetrical tetrahydroxyazepanes as inhibitors of glycosidases and HIV/FIV proteases, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 4, 2055-2069, 1996
|
| 1996 |
T. G. Marron, T. J. Woltering, G. Weitz-Schmidt, C. H. Wong, C-Mannose derivatives as potent mimics of sialyl Lewis X, Tetrahedron Lett, vol. 37, 9037-9040, 1996
|
| 1996 |
T. J. Woltering, G. Weitz-Schmidt, C. H. Wong, C-Fucopeptides as selectin antagonists: Attachment of lipid moieties enhances the activity, Tetrahedron Lett, vol. 37, 9033-9036, 1996
|
| 1996 |
C. H. Wong, R. L. Pederson, Y. F. Wang, Azido diacetal propane derivatives, US Patent, vol. #5,565,585, 1996
|
| 1996 |
C. H. Wong, J. R. Durrwachter, R. L. Pederson, Aldolase catalyzed stereoselective synthesis of arabinohexulose, xyloheptulose, threohexulose and xylohexulose, US Patent, vol. #5,576,426, 1996
|
| 1996 |
R. D. Kidd, H. P. Yennawar, P. Sears, C. H. Wong, G. K. Farber, A weak calcium binding site in subtilisin BPN' has a dramatic effect on protein stability, J Am Chem Soc, vol. 118, 1645-1650, 1996
|
| 1996 |
T. Kimura, S. Takayama, H. M. Huang, C. H. Wong, A practical method for the synthesis of N-acetyl-D-lactosamine derivatives by the tandem use of galactose oxidase and beta-galactosidase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 35, 2348-2350, 1996
|
| 1996 |
T. Kimura, S. Takayama, H. Huang, C. H. Wong, A practical method for the synthesis of N-acetyl-D-lactosamine derivatives by the tandem use of galactose oxidase and -galactosidase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 35, 2348-2349, 1996
|
| 1996 |
M. Hendrix, C. H. Wong, A chemoenzymatic approach to carbohydrate-mediated cell adhesion, Pure Appl Chem, vol. 68, 2081-2087, 1996
|
| 1996 |
M. Hendrix, C. H. Wong, A chemo-enzymatic approach to the study of carbohydrate recognition in biological systems, ENANTIOMER, vol. 1, 305-310, 1996
|
| 1996 |
C. H. Wong, W. J. Hennen, 2-Deoxyderivatives of N-acetylneuraminic acid and their preparation, US Patent, vol. #5,554,771, 1996
|
| 1995 |
T. Kajimoto, C. H. Wong, Transition-state analog inhibitors for N-acetylglucosaminyltransfer enzymes, RIKEN Review, vol. 8, 13-14, 1995
|
| 1995 |
C. H. Wong, Topochemistry and inhibition of carbohydrate-mediated cell adhesion, In: New Perspectives in Drug Design, vol. 35-50, 1995
|
| 1995 |
W. Yuan, C. H. Wong, B. Samuelsson, Tight-binding inhibitors of leukotriene A.sub.4 hydrolase, US Patent, vol. #5,455,271, 1995
|
| 1995 |
W. C. Chou, C. Fotsch, C. H. Wong, Synthesis of Nitrocyclitols Based on Enzymatic Aldol Reaction and Intramolecular Nitroaldol Reaction, J Org Chem, vol. 60, 2916-2917, 1995
|
| 1995 |
H. M. Huang, C. H. Wong, Synthesis of Biologically-Active Sialyl-Lewis-X Mimetics, J Org Chem, vol. 60, 3100-3106, 1995
|
| 1995 |
H. J. M. Gijsen, W. Chi Huey, Synthesis of a Cyclitol via a Tandem Enzymatic Aldol - Intramolecular Horner-Wadsworth-Emmons Reaction, Tetrahedron Lett, vol. 36, 7057-7060, 1995
|
| 1995 |
S. Hiranuma, T. Shimizu, T. Nakata, T. Kajimoto, W. Chi Huey, Synthesis and Inhibition Analysis of Five-Membered Homoazasugars from -Arabinofuranose via an S2 Reaction of the Chloromethylsulfonate, Tetrahedron Lett, vol. 36, 8247-8250, 1995
|
| 1995 |
C. H. Wong, L. Provencher, J. A. Porco, S. H. Jung, Y. F. Wang, L. R. Chen, R. Wang, D. H. Steensma, Synthesis and Evaluation of Homoazasugars as Glycosidase Inhibitors, J Org Chem, vol. 60, 1492-1501, 1995
|
| 1995 |
H. J. M. Gijsen, C. H. Wong, Sequential One-Pot Aldol Reactions Catalyzed by 2-Deoxyribose-5-Phosphate Aldolase and Fructose-1,6-Diphosphate Aldolase, J Am Chem Soc, vol. 117, 2947-2948, 1995
|
| 1995 |
H. J. M. Gijsen, C. H. Wong, Sequential 3-Substrate and 4-Substrate Aldol Reactions Catalyzed by Aldolases, J Am Chem Soc, vol. 117, 7585-7591, 1995
|
| 1995 |
D. H. Slee, K. L. Laslo, J. H. Elder, I. R. Ollmann, A. Gustchina, J. Kervinen, A. Zdanov, A. Wlodawer, C. H. Wong, Selectivity in the Inhibition of Hiv and Fiv Protease - Inhibitory and Mechanistic Studies of Pyrrolidine-Containing Alpha-Keto Amide and Hydroxyethylamine Core Structures, J Am Chem Soc, vol. 117, 11867-11878, 1995
|
| 1995 |
C. H. Wong, E. Garciajunceda, L. R. Chen, O. Blanco, H. J. M. Gijsen, D. H. Steensma, Recombinant 2-Deoxyribose-5-Phosphate Aldolase in Organic-Synthesis - Use of Sequential 2-Substrate and 3-Substrate Aldol Reactions, J Am Chem Soc, vol. 117, 3333-3339, 1995
|
| 1995 |
C. W. Bradshaw, C. H. Wong, G. J. Shen, Pseudomonas sp. ATCC 49794 PED alcohol dehydrogenase, US Patent, vol. #5,385,833, 1995
|
| 1995 |
T. Ikeda, T. Kajimoto, T. Nohara, J. e. Kinjo, C. H. Wong, Preparation of a neoglycolipid carrying the oligosaccharide component of saponin from Albizzia julibrissin, Tetrahedron Lett, vol. 36, 1509-1510, 1995
|
| 1995 |
A. Wetterholm, J. Z. Haeggstrom, B. Samuelsson, W. Yuan, B. Munoz, C. H. Wong, Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes, J Pharmacol Exp Ther, vol. 275, 31-37, 1995
|
| 1995 |
T. Ikeda, T. Kajimoto, C. H. Wong, Oligosaccharides components in traditional Chinese medicines and the liposomes carrying oligosaccharides, RIKEN Review, vol. 8, 21-22, 1995
|
| 1995 |
C. H. Wong, Y. Ichikawa, Oligosaccharide enzyme substrates and inhibitors: Methods and composition, US Patent, vol. #5,461,143, 1995
|
| 1995 |
P. G. Wang, W. Fitz, C. H. Wong, Making Complex Carbohydrates Via Enzymatic Routes, CHEMTECH, vol. 25, 22-32, 1995
|
| 1995 |
S. A. Defrees, W. Kosch, W. Way, J. C. Paulson, S. Sabesan, R. L. Halcomb, D. H. Huang, Y. Ichikawa, C. H. Wong, Ligand Recognition by E-Selectin - Synthesis, Inhibitory Activity, and Conformational-Analysis of Bivalent Sialyl-Lewis-X Analogs, J Am Chem Soc, vol. 117, 66-79, 1995
|
| 1995 |
C. H. Wong, C. W. Bradshaw, Lactobacillus kefir alcohol dehydrogenase, US Patent, vol. #5,342,767, 1995
|
| 1995 |
V. P. Vassilev, T. Uchiyama, T. Kajimoto, C. H. Wong, L-threonine aldolase in organic synthesis: Preparation of novel [beta]-hydroxy-[alpha]-amino acids, Tetrahedron Lett, vol. 36, 4081-4084, 1995
|
| 1995 |
I. R. Ollmann, J. H. Hogg, B. Munoz, J. Z. Haeggstrom, B. Samuelsson, C. H. Wong, Investigation of the inhibition of leukotriene A4 hydrolase, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 3, 969-995, 1995
|
| 1995 |
C. H. Wong, Intervention of carbohydrate-mediated biological recognitions, RIKEN Review, vol. 8, 3月4日, 1995
|
| 1995 |
C. H. Wong, K.K.C. Liu, Fructosyl C-glycoside nucleoside analogs, US Patent, vol. #5,393,879, 1995
|
| 1995 |
I. Henderson, C. H. Wong, Formation of carbon-carbon bonds, In: Handbook of enzyme catalysis in organic synthesis, vol. 547-580, 1995
|
| 1995 |
J. M. Fang, C. H. Lin, C. W. Bradshaw, C. H. Wong, Enzymes in Organic-Synthesis - Oxidoreductions (Pg 967, 1995), JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, vol. 1781-1781, 1995
|
| 1995 |
J. M. Fang, C. H. Lin, C. W. Bradshaw, C. H. Wong, Enzymes in Organic-Synthesis - Oxidoreductions, JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, vol. 967-978, 1995
|
| 1995 |
C. H. Wong, R. L. Halcomb, Y. Ichikawa, T. Kajimoto, Enzymes in Organic-Synthesis - Application to the Problems of Carbohydrate-Recognition .2, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 34, 521-546, 1995
|
| 1995 |
C. H. Wong, R. L. Halcomb, Y. Ichikawa, T. Kajimoto, Enzymes in Organic-Synthesis - Application to the Problems of Carbohydrate-Recognition .1, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 34, 412-432, 1995
|
| 1995 |
M. Hendrix, C. H. Wong, Enzymes in organic synthesis: Application to the study of carbohydrate recognition, Proceedings of the Chiral '95 USA Symposium, vol. 27-34, 1995
|
| 1995 |
C. Deluca, M. Lansing, I. Martini, F. Crescenzi, G. J. Shen, M. Oregan, C. H. Wong, Enzymatic-Synthesis of Hyaluronic-Acid with Regeneration of Sugar Nucleotides, J Am Chem Soc, vol. 117, 5869-5870, 1995
|
| 1995 |
C. H. Lin, G. J. Shen, E. Garciajunceda, C. H. Wong, Enzymatic-Synthesis and Regeneration of 3'-Phosphoadenosine 5'-Phosphosulfate (Paps) for Regioselective Sulfation of Oligosaccharides, J Am Chem Soc, vol. 117, 8031-8032, 1995
|
| 1995 |
R. L. Halcomb, C. H. Wong, Enzymatic synthesis of glycoside bonds, In: Handbook of enzyme catalysis in organic synthesis, vol. 279-316, 1995
|
| 1995 |
C. H. Lin, M. Shimazaki, C. H. Wong, M. Koketsu, L. R. Juneja, M. Kim, Enzymatic synthesis of a sialyl Lewis X dimer from egg yolk as an inhibitor of E-selectin, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 3, 1625-1630, 1995
|
| 1995 |
C. H. Wong, G. C. Look, Enzymatic process for producing a galactosyl b-1,3-glycal disaccharide using b-galactosidase, US Patent, vol. #5,403,726, 1995
|
| 1995 |
C. H. Wong, Enzymatic and Chemoenzymatic Synthesis of Carbohydrates, Pure Appl Chem, vol. 67, 1609-1616, 1995
|
| 1995 |
S. Hiranuma, V. P. Vassilev, T. Kajimoto, C. H. Wong, Design of oligosaccharide mimetics with higher stability and simpler structures than parent oligosaccharides, RIKEN Review, vol. 8, 19-20, 1995
|
| 1995 |
T. Uchiyama, V. P. Vassilev, T. Kajimoto, W. C. Wong, H. M. Huang, C. C. Lin, C. H. Wong, Design and Synthesis of Sialyl-Lewis-X Mimetics, J Am Chem Soc, vol. 117, 5395-5396, 1995
|
| 1995 |
E. A. Stura, S. Ghosh, E. Garcia Junceda, L. Chen, C. H. Wong, I. A. Wilson, Crystallization and preliminary crystallographic data for class I deoxyribose-5-phosphate aldolase from Escherichia coli: an application of reverse screening, Proteins, vol. 22, 67-72, 1995
|
| 1995 |
T. Sugai, C. H. Lin, G. J. Shen, C. H. Wong, CMP-KDO synthetase: overproduction and application to the synthesis of CMP-KDO and analogs, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 3, 313-320, 1995
|
| 1995 |
E. Garcia Junceda, G. J. Shen, R. Alajarin, C. H. Wong, Cloning and overexpression of rhamnose isomerase and fucose isomerase, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 3, 1349-1355, 1995
|
| 1995 |
V. P. Vassilev, T. Kajimoto, C. H. Wong, Application of L-allo-threonine aldolase in the synthesis of glycoconjugate precursors, RIKEN Review, vol. 8, 25-26, 1995
|
| 1995 |
V. P. Vassilev, T. Uchiyama, T. Kajimoto, C. H. Wong, An efficient chemo-enzymatic synthesis of [alpha]-amino-[beta]-hydroxy-[gamma]-butyrolactone, Tetrahedron Lett, vol. 36, 5063-5064, 1995
|
| 1995 |
J. H. Hogg, I. R. Ollmann, J. Z. Haeggstrom, A. Wetterholm, B. Samuelsson, C. H. Wong, Amino hydroxamic acids as potent inhibitors of leukotriene A4 hydrolase, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 3, 1405-1415, 1995
|
| 1995 |
W. Fitz, J. R. Schwark, C. H. Wong, Aldotetroses and C(3)-Modified Aldohexoses as Substrates for N-Acetylneuraminic Acid Aldolase - a Model for the Explanation of the Normal and the Inversed Stereoselectivity, J Org Chem, vol. 60, 3663-3670, 1995
|
| 1995 |
R. Alajarin, E. Garciajunceda, C. H. Wong, A Short Enzymatic-Synthesis of L-Glucose from Dihydroxyacetone Phosphate and L-Glyceraldehyde, J Org Chem, vol. 60, 4294-4295, 1995
|
| 1995 |
E. Garcia Junceda, G. J. Shen, T. Sugai, C. H. Wong, A new strategy for the cloning, overexpression and one step purification of three DHAP-dependent aldolases: rhamnulose-1-phosphate aldolase, fuculose-1-phosphate aldolase and tagatose-1,6-diphosphate aldolase, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 3, 945-953, 1995
|
| 1994 |
H. J. M. Gijsen, C. H. Wong, Unprecedented Asymmetric Aldol Reactions with 3 Aldehyde Substrates Catalyzed by 2-Deoxyribose-5-Phosphate Aldolase, J Am Chem Soc, vol. 116, 8422-8423, 1994
|
| 1994 |
Y. Ichikawa, C. H. Wong, Topochemistry and inhibition of selectin-mediated cell adhesion: Chemical-enzymatic synthesis of inhibitors related to E-selectin recognition, In: Complex Carbohydrates in Drug Research. The Alfred Benzon Symposium, vol. 36, 118-133, 1994
|
| 1994 |
H. Yuasa, T. Kajimoto, C. H. Wong, Synthesis of iminothiasugar as a potential transition-state analog inhibitor of glycosyltransfer reactions, Tetrahedron Lett, vol. 35, 8243-8246, 1994
|
| 1994 |
I. Henderson, K. B. Sharpless, C. H. Wong, Synthesis of Carbohydrates Via Tandem Use of the Osmium-Catalyzed Asymmetric Dihydroxylation and Enzyme-Catalyzed Aldol Addition-Reactions, J Am Chem Soc, vol. 116, 558-561, 1994
|
| 1994 |
C. H. Fotsch, C. H. Wong, Synthesis of a guanidino-sugar as a glycosyl cation mimic, Tetrahedron Lett, vol. 35, 3481-3484, 1994
|
| 1994 |
Y. Ichikawa, R. L. Halcomb, C. H. Wong, Sticky Solutions, Chemistry in Britain, vol. 30, 117-+, 1994
|
| 1994 |
R. L. Halcomb, H. M. Huang, C. H. Wong, Solution-Phase and Solid-Phase Synthesis of Inhibitors of Helicobacter-Pylori Attachment and E-Selectin-Mediated Leukocyte Adhesion, J Am Chem Soc, vol. 116, 11315-11322, 1994
|
| 1994 |
M. Schuster, P. Wang, J. C. Paulson, C. H. Wong, Solid-Phase Chemical-Enzymatic Synthesis of Glycopeptides and Oligosaccharides, J Am Chem Soc, vol. 116, 1135-1136, 1994
|
| 1994 |
Y. F. Wang, Y. Takaoka, C. H. Wong, Remarkable Stereoselectivity in the Inhibition of Alpha-Galactosidase from Coffee Bean by a New Polyhydroxypyrrolidine Inhibitor, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 33, 1242-1244, 1994
|
| 1994 |
Y. Ichikawa, R. Wang, C. H. Wong, Regeneration of sugar nucleotide for enzymatic oligosaccharide synthesis, Methods Enzymol, vol. 247, 107-127, 1994
|
| 1994 |
G. F. Herrmann, P. Wang, G. J. Shen, C. H. Wong, Recombinant Whole Cells as Catalysts for the Enzymatic-Synthesis of Oligosaccharides and Glycopeptides, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 33, 1241-1242, 1994
|
| 1994 |
C. H. Wong, M. Schuster, Process for solid-phase glycopeptide synthesis, US Patent, vol. #5,369,017, 1994
|
| 1994 |
C. H. Wong, T. Kajimoto, K.K.C. Liu, Lihren Chen, Process for forming Omega-deoxy-azasugars, US Patent, vol. #5,276,120, 1994
|
| 1994 |
G. F. Herrmann, P. Wang, G. J. Shen, E. Garciajunceda, S. H. Khan, K. L. Matta, C. H. Wong, Large-Scale Production of Recombinant Alpha-1,2-Mannosyltransferase from Escherichia-Coli for the Study of Acceptor Specificity and Use of the Recombinant Whole Cells in Synthesis, J Org Chem, vol. 59, 6356-6362, 1994
|
| 1994 |
J. L. Marquardt, E. D. Brown, W. S. Lane, T. M. Haley, Y. Ichikawa, C. H. Wong, C. T. Walsh, Kinetics, stoichiometry, and identification of the reactive thiolate in the inactivation of UDP-GlcNAc enolpyruvoyl transferase by the antibiotic fosfomycin, Biochemistry, vol. 33, 10646-10651, 1994
|
| 1994 |
C. H. Wong, T. Sugai, G. J. Shen, KDO aldolase and condensation reactions employed therewith, US Patent, vol. #5,358,859, 1994
|
| 1994 |
H. Kondo, S. Aoki, Y. Ichikawa, R. L. Halcomb, H. Ritzen, C. H. Wong, Glycosyl Phosphites as Glycosylation Reagents - Scope and Mechanism, J Org Chem, vol. 59, 864-877, 1994
|
| 1994 |
S. Aoki, H. Kondo, C. H. Wong, Glycosyl phosphites as glycosylation reagents, Methods Enzymol, vol. 247, 193-211, 1994
|
| 1994 |
L. Provencher, D. H. Steensma, C. H. Wong, Five-membered ring azasugars as potent inhibitors of alpha-L-rhamnosidase (naringinase) from Penicillium decumbens, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 2, 1179-1188, 1994
|
| 1994 |
G. Siuzdak, Z. L. Zheng, J. Y. Rhamphal, Y. Ichikawa, K. C. Nicolaou, F. C. A. Gaeta, K. S. Chatman, C. H. Wong, Examination of the Sialyl-Lewis-X Calcium Complex by Electrospray Mass-Spectrometry, Bioorg Med Chem Lett, vol. 4, 2863-2866, 1994
|
| 1994 |
C. H. Wong, G. M. Whitesides, Enzymes in Synthetic Organic Chemistry, In: Pergamon Press, 1994
|
| 1994 |
J. M. Fang, C. H. Wong, Enzymes in Organic-Synthesis - Alteration of Reversible-Reactions to Irreversible-Processes, Synlett, vol. 393-402, 1994
|
| 1994 |
R. L. Halcomb, W. Fitz, C. H. Wong, Enzymatic-Synthesis of 7-Deoxy-N-Acetylneuraminic Acid and 7-O-Methyl-N-Acetylneuraminic Acid, Tetrahedron-Asymmetry, vol. 5, 2437-2442, 1994
|
| 1994 |
P. Sears, M. Schuster, P. Wang, K. Witte, C. H. Wong, Engineering Subtilisin for Peptide Coupling - Studies on the Effects of Counterions and Site-Specific Modifications on the Stability and Specificity of the Enzyme, J Am Chem Soc, vol. 116, 6521-6530, 1994
|
| 1994 |
W. Fitz, C. H. Wong, Combined Use of Subtilisin and N-Acetylneuraminic Acid Aldolase for the Synthesis of a Fluorescent Sialic-Acid, J Org Chem, vol. 59, 8279-8280, 1994
|
| 1994 |
C. H. Wong, F. Gaeta, Combined use of b-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one-pot synthesis of oligosaccharides, US Patent, vol. #5,374,541, 1994
|
| 1994 |
I. Henderson, E. Garcia Junceda, K. K. Liu, Y. L. Chen, G. J. Shen, C. H. Wong, Cloning, overexpression and isolation of the type II FDP aldolase from E. coli for specificity study and synthetic application, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 2, 837-843, 1994
|
| 1994 |
I. Henderson, K. Laslo, C. H. Wong, Chemoenzymatic synthesis of homoazasugars, Tetrahedron Lett, vol. 35, 359-362, 1994
|
| 1994 |
R. L. Halcomb, C. H. Wong, Asymmetric synthesis based on enzymes, In: Stereocontrolled Organic Synthesis, vol. 413, 1994
|
| 1994 |
S. H. Jung, J. H. Jeong, P. Miller, C. H. Wong, An Efficient Multigram-Scale Preparation of Dihydroxyacetone Phosphate, J Org Chem, vol. 59, 7182-7184, 1994
|
| 1994 |
B. Munoz, C. Z. Giam, C. H. Wong, Alpha-ketoamide Phe-Pro isostere as a new core structure for the inhibition of HIV protease, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 2, 1085-1090, 1994
|
| 1994 |
C. H. Wong, K.K.C. Liu, Aldolase enzyme process for making 5-azido-5-deoxy-hexulose-1-phosphate, US Patent, vol. #5,352,591, 1994
|
| 1994 |
W. C. Chou, L. H. Chen, J. M. Fang, C. H. Wong, A New Route to Deoxythiosugars Based on Aldolases, J Am Chem Soc, vol. 116, 6191-6194, 1994
|
| 1994 |
C. H. Wong, G. J. Shen, Y. Ichikawa, A method and composition for synthesizing sialylated glycosyl compounds, US Patent, vol. #5,278,299, 1994
|
| 1994 |
S. Hiranuma, Kajimoto, Tetsuya, C. H. Wong, A facile synthesis of 1-thiopentofuranoside, Tetrahedron Lett, vol. 35, 5257-5260, 1994
|
| 1993 |
T. Sugai, H. Ritzen, C. H. Wong, Towards the Chemoenzymatic Synthesis of Lipid-A, Tetrahedron-Asymmetry, vol. 4, 1051-1058, 1993
|
| 1993 |
P. Wang, M. Schuster, Y. F. Wang, C. H. Wong, Synthesis of Phospholipid Inhibitor Conjugates by Enzymatic Transphosphatidylation with Phospholipase-D, J Am Chem Soc, vol. 115, 10487-10491, 1993
|
| 1993 |
R. L. Halcomb, C. H. Wong, Synthesis of Oligosaccharides, Glycopeptides, and Glycolipids, CURRENT OPINION IN STRUCTURAL BIOLOGY, vol. 3, 694-700, 1993
|
| 1993 |
T. Sugai, G. J. Shen, Y. Ichikawa, C. H. Wong, Synthesis of 3-Deoxy-D-Manno-2-Octulosonic Acid (Kdo) and Its Analogs Based on Kdo Aldolase-Catalyzed Reactions, J Am Chem Soc, vol. 115, 413-421, 1993
|
| 1993 |
M. M. Sim, H. Kondo, C. H. Wong, Synthesis and Use of Glycosyl Phosphites - an Effective Route to Glycosyl Phosphates, Sugar Nucleotides, and Glycosides, J Am Chem Soc, vol. 115, 2260-2267, 1993
|
| 1993 |
Y. Ichikawa, G. C. Look, G. J. Shen, P. Sears, P. Wang, C. H. Wong, Recent development in enzymatic synthesis of oligosaccharides and glycopeptides, In: Carbohydrates and Carbohydrate Polymers, vol. 1月16日, 1993
|
| 1993 |
C. H. Wong, Y. Ichikawa, T. Kajimoto, K. K. C. Liu, G. J. Shen, C. H. Lin, Y. F. Wang, D. P. Dumas, Y. C. Lin, R. Wang, G. C. Look, Practical Synthesis of Carbohydrates Based on Aldolases and Glycosyl Transferases, Pure Appl Chem, vol. 65, 803-808, 1993
|
| 1993 |
M. Schuster, B. Munoz, W. Yuan, C. H. Wong, Papain catalyzed synthesis of peptide isosteres, Tetrahedron Lett, vol. 34, 1247-1250, 1993
|
| 1993 |
S. A. Defrees, F. C. A. Gaeta, Y. C. Lin, Y. Ichikawa, C. H. Wong, Ligand Recognition by E-Selectin - Analysis of Conformation and Activity of Synthetic Monomeric and Bivalent Sialyl Lewis-X Analogs, J Am Chem Soc, vol. 115, 7549-7550, 1993
|
| 1993 |
C. H. Wong, C. W. Bradshaw, Lactobacillus kefir alcohol dehydrogenase, US Patent, vol. #5,225,339, 1993
|
| 1993 |
Y. Takaoka, T. Kajimoto, C. H. Wong, Inhibition of N-Acetylglucosaminyltransfer Enzymes - Chemical-Enzymatic Synthesis of New 5-Membered Acetamido Azasugars, J Org Chem, vol. 58, 4809-4812, 1993
|
| 1993 |
G. Siuzdak, Y. Ichikawa, T. J. Caulfield, B. Munoz, C. H. Wong, K. C. Nicolaou, Evidence of Ca2+-Dependent Carbohydrate Association through Ion Spray Mass-Spectrometry, J Am Chem Soc, vol. 115, 2877-2881, 1993
|
| 1993 |
P. Wang, G. J. Shen, Y. F. Wang, Y. Ichikawa, C. H. Wong, Enzymes in Oligosaccharide Synthesis - Active-Domain Overproduction, Specificity Study, and Synthetic Use of an Alpha-1,2-Mannosyltransferase with Regeneration of Gdp-Man, J Org Chem, vol. 58, 3985-3990, 1993
|
| 1993 |
G. C. Look, C. H. Fotsch, C. H. Wong, Enzyme-Catalyzed Organic Synthesis: Practical Routes to Aza Sugars and Their Analogs for Use as Glycoprocessing Inhibitors, Accounts Chem Res, vol. 26, 182-190, 1993
|
| 1993 |
C. H. Wong, M. Schuster, P. Wang, P. Sears, Enzymatic-Synthesis of N-Linked and O-Linked Glycopeptides, J Am Chem Soc, vol. 115, 5893-5901, 1993
|
| 1993 |
W. Yuan, B. Munoz, C. H. Wong, J. Z. Haeggstrom, A. Wetterholm, B. Samuelsson, Development of selective tight-binding inhibitors of leukotriene A4 hydrolase, J Med Chem, vol. 36, 211-220, 1993
|
| 1993 |
C. H. Wong, Development of Enzymes for Chemoenzymatic Synthesis, Chimia, vol. 47, 127-132, 1993
|
| 1993 |
Yi Fong Wang, David Dumas P., C. H. Wong, Chemo-enzymatic synthesis of five-membered azasugars as inhibitors of fucosidase and fucosyltransferase: An issue regarding the stereochemistry discrimination at transition states, Tetrahedron Lett, vol. 34, 403-406, 1993
|
| 1993 |
T. Kajimoto, T. Sugai, C. H. Wong, Aldolase Catalyzed Reaction for Carbohydrate Synthesis, TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY, vol. 5, 193-207, 1993
|
| 1993 |
G. F. Herrmann, Y. Ichikawa, C. Wandrey, F. C. A. Gaeta, J. C. Paulson, C. H. Wong, A new multi-enzyme system for a one-pot synthesis of sialyl oligosaccharides: Combined use of [beta]-galactosidase and [alpha](26)-sialyltransferase coupled with regeneration in situ of CMP-sialic acid, Tetrahedron Lett, vol. 34, 3091-3094, 1993
|
| 1993 |
G. C. Look, Y. Ichikawa, G. J. Shen, P. W. Cheng, C. H. Wong, A Combined Chemical and Enzymatic Strategy for the Construction of Carbohydrate-Containing Antigen Core Units, J Org Chem, vol. 58, 4326-4330, 1993
|
| 1993 |
C. H. Wong, K.K.C. Liu, 2-Methyl-5-hydroxylmethyl and 2,5-dimethyl-3,4-dihydroxypyrrolidines, US Patent, vol. #5,229,523, 1993
|
| 1993 |
C. H. Wong, W. J. Hennen, 2-Deoxy Derivatives of N-Acetyl Neuraminic Acid and Their Preparation, US Patent, vol. #5,239,091, 1993
|
| 1992 |
C. H. Lin, T. Sugai, R. L. Halcomb, Y. Ichikawa, C. H. Wong, Unusual Stereoselectivity in Sialic-Acid Aldolase-Catalyzed Aldol Condensations - Synthesis of Both Enantiomers of High-Carbon Monosaccharides, J Am Chem Soc, vol. 114, 10138-10145, 1992
|
| 1992 |
C. H. Wong, D. P. Dumas, Y. Ichikawa, K. Koseki, S. J. Danishefsky, B. W. Weston, J. B. Lowe, Specificity, Inhibition, and Synthetic Utility of a Recombinant Human Alpha-1,3-Fucosyl-Transferase, J Am Chem Soc, vol. 114, 7321-7322, 1992
|
| 1992 |
E. Fernholz, D. Schloeder, K. K. C. Liu, C. W. Bradshaw, H. M. Huang, K. Janda, R. A. Lerner, C. H. Wong, Specificity of Antibody-Catalyzed Transesterifications Using Enol Esters - a Comparison with Lipase Reactions, J Org Chem, vol. 57, 4756-4761, 1992
|
| 1992 |
S. J. Danishefsky, J. Gervay, J. M. Peterson, F. E. McDonald, K. Koseki, T. Oriyama, D. A. Griffith, C. H. Wong, D. P. Dumas, Remarkable Regioselectivity in the Chemical Glycosylation of Glycal Acceptors - a Concise Solution to the Synthesis of Sialyl-Lewis-X Glycal, J Am Chem Soc, vol. 114, 8329-8331, 1992
|
| 1992 |
C. H. Wong, R. Wang, Y. Ichikawa, Regeneration of Sugar Nucleotide for Enzymatic Oligosaccharide Synthesis - Use of Gal-1-Phosphate Uridyltransferase in the Regeneration of Udp-Galactose, Udp-2-Deoxygalactose, and Udp-Galactosamine, J Org Chem, vol. 57, 4343-4344, 1992
|
| 1992 |
K. K. C. Liu, R. L. Pederson, C. H. Wong, Rabbit muscle aldolase catalyzed preparation of 6-deoxy-6-chloro-D-fructose and 6-deoxy-6-chloro-L-sorbose from 3-chloro-2-hydroxypropanal and DHAP, In: Preparative Biotransformations, vol. 04:01.1, 1992
|
| 1992 |
J. L. C. Liu, G. J. Shen, Y. Ichikawa, J. F. Rutan, G. Zapata, W. F. Vann, C. H. Wong, Overproduction of Cmp-Sialic Acid Synthetase for Organic-Synthesis, J Am Chem Soc, vol. 114, 3901-3910, 1992
|
| 1992 |
W. Yuan, C. H. Wong, J. Z. Haeggstrom, A. Wetterholm, B. Samuelsson, Novel Tight-Binding Inhibitors of Leukotriene-a(4) Hydrolase, J Am Chem Soc, vol. 114, 6552-6553, 1992
|
| 1992 |
R. L. Pederson, C. H. Wong, Lipoprotein lipase catalyzed kinetic resolution of 2-acetoxy-3-azidopropanal diethyl acetal, In: Preparative Biotransformations, vol. 01:06.1, 1992
|
| 1992 |
C. W. Bradshaw, W. Hummel, C. H. Wong, Lactobacillus-Kefir Alcohol-Dehydrogenase - a Useful Catalyst for Synthesis, J Org Chem, vol. 57, 1532-1536, 1992
|
| 1992 |
C. H. Wong, l-Isomeric sugars having formed stereogenic centers of (R-configuration: Methods and compositions, US Patent, vol. #5,162,513, 1992
|
| 1992 |
C. H. Wong, J. R. Durrwachter, R. L. Pederson, Fructose-1,6-diphosphate Aldolase Catalyzed Stereoselective Synthesis of Sugars, US Patent, vol. #5,143,831, 1992
|
| 1992 |
C. H. Wong, K. K. C. Liu, T. Kajimoto, L. H. Chen, Z. Y. Zhong, D. P. Dumas, J. L. C. Liu, Y. Ichikawa, G. J. Shen, Enzymes for Carbohydrate and Peptide Syntheses, Pure Appl Chem, vol. 64, 1197-1202, 1992
|
| 1992 |
Y. Ichikawa, G. C. Look, C. H. Wong, Enzyme-catalyzed oligosaccharide synthesis, Anal Biochem, vol. 202, 215-238, 1992
|
| 1992 |
C. W. Bradshaw, J. J. Lalonde, C. H. Wong, Enzymatic synthesis of (R) and (S) 1-deuterohexanol, Appl Biochem Biotechnol, vol. 33, 15-24, 1992
|
| 1992 |
W. J. Hennen, H. M. Sweers, Y. F. Wang, C. H. Wong, Enzymatic regioselective hydrolysis of a peracetylated furanose derivative, In: Preparative Biotransformations, vol. 01:07.1, 1992
|
| 1992 |
K. K. C. Liu, C. H. Wong, Enzymatic Halohydration of Glycals, J Org Chem, vol. 57, 3748-3750, 1992
|
| 1992 |
C. H. Wong, Engineering enzymes for the synthesis of carbohydrates and peptides, In: Harnessing Biotechnology for the 21st Century. ACS Conference Proceedings Series, vol. 168-171, 1992
|
| 1992 |
C. H. Wong, Engineering enzymes for chemoenzymatic synthesis Part II: Modifying proteases for peptide synthesis, TIBTECH, vol. 10(110, 378-381, 1992
|
| 1992 |
C. H. Wong, Engineering enzymes for chemoenzymatic synthesis Part I: Practical routes to aza-sugars and complex carbohydrates, TIBTECH, vol. 10(10), 337-341, 1992
|
| 1992 |
C. H. Wong, Y. F. Wang, W. J. Hennen, Enantio- and Regioselective Synthesis of Organic Compounds Using Enol Esters as Irreversible Transacylation Reagents, US Patent, vol. #5,106,750, 1992
|
| 1992 |
Y. Ichikawa, M. M. Sim, C. H. Wong, Efficient Chemical Synthesis of Gdp-Fucose, J Org Chem, vol. 57, 2943-2946, 1992
|
| 1992 |
C. H. Wong, K. K. Liu, T. Kajimoto, L. Chen, Z. Zhong, Y. Ichikawa, G. J. Shen, Developing better enzymes for organic synthesis, Enzyme Engineering XI, Ann. N.Y. Acad. Sci, vol. 672, 343-351, 1992
|
| 1992 |
L. R. Chen, D. P. Dumas, C. H. Wong, Deoxyribose-5-Phosphate Aldolase as a Catalyst in Asymmetric Aldol Condensation, J Am Chem Soc, vol. 114, 741-748, 1992
|
| 1992 |
G. J. Shen, C. H. Wong, Construction of a diverse Fab expression library from autoimmunized mice based on an improved preparation of cloning arms from bacteriophage vectors: a new library with potential for screening of biocatalysts, Biocatalysis and Biotransformation, vol. 6, 101-114, 1992
|
| 1992 |
Y. C. Lin, C. W. Hummel, D. H. Huang, Y. Ichikawa, K. C. Nicolaou, C. H. Wong, Conformational Studies of Sialyl Lewis-X in Aqueous-Solution, J Am Chem Soc, vol. 114, 5452-5454, 1992
|
| 1992 |
G. J. Shen, J. L. C. Liu, C. H. Wong, Cloning and overexpression of a tagged CMP-N-acetylneuraminic acid synthetase from E. coli using a lambda phage system and application of the enzyme to the synthesis of CMP-N-acetylneuraminic acid, Biocatalysis and Biotransformation, vol. 6, 31-42, 1992
|
| 1992 |
H. Fu, H. Kondo, Y. Ichikawa, G. C. Look, C. H. Wong, Chloroperoxidase-Catalyzed Asymmetric-Synthesis - Enantioselective Reactions of Chiral Hydroperoxides with Sulfides and Bromohydration of Glycals, J Org Chem, vol. 57, 7265-7270, 1992
|
| 1992 |
C. H. Wong, Y. Ichikawa, T. Kajimoto, K. K. C. Liu, Y. C. Lin, G. C. Look, Chemical-enzymatic synthesis of carbohydrates, In: Microbial Reagents in Organic Synthesis. NATO ASI Series, vol. 381, 35-42, 1992
|
| 1992 |
Y. Ichikawa, Y. C. Lin, D. P. Dumas, G. J. Shen, E. Garciajunceda, M. A. Williams, R. Bayer, C. Ketcham, L. E. Walker, J. C. Paulson, C. H. Wong, Chemical-Enzymatic Synthesis and Conformational-Analysis of Sialyl Lewis-X and Derivatives, J Am Chem Soc, vol. 114, 9283-9298, 1992
|
| 1992 |
P.N. Bryan, M. Pantoliano, M.L. Rollence, C. H. Wong, Biosynthetic uses of thermostable proteases, US Patent, vol. #5,116,741, 1992
|
| 1992 |
H. Kondo, Y. Ichikawa, C. H. Wong, Beta-Sialyl Phosphite and Phosphoramidite - Synthesis and Application to the Chemoenzymatic Synthesis of Cmp-Sialic Acid and Sialyl Oligosaccharides, J Am Chem Soc, vol. 114, 8748-8750, 1992
|
| 1992 |
D. P. Dumas, T. Kajimoto, K. K. C. Liu, C. H. Wong, D. B. Berkowitz, S. J. Danishefsky, Azasugar and Glycal Inhibitors of Alpha-L-Fucosidase, Bioorg Med Chem Lett, vol. 2, 33-36, 1992
|
| 1992 |
C. W. Bradshaw, H. Fu, G. J. Shen, C. H. Wong, A Pseudomonas Sp Alcohol-Dehydrogenase with Broad Substrate-Specificity and Unusual Stereospecificity for Organic-Synthesis, J Org Chem, vol. 57, 1526-1532, 1992
|
| 1992 |
K. K. C. Liu, C. H. Wong, A New Strategy for the Synthesis of Nucleoside Analogs Based on Enzyme-Catalyzed Aldol Reactions, J Org Chem, vol. 57, 4789-4791, 1992
|
| 1992 |
G. C. Look, C. H. Wong, A facile enzymatic synthesis of gal[beta]1,3glucal: a key intermediate for the synthesis of Lea and sialyl Lea, Tetrahedron Lett, vol. 33, 4253-4256, 1992
|
| 1991 |
K. K. C. Liu, T. Kajimoto, L. R. Chen, Z. Y. Zhong, Y. Ichikawa, C. H. Wong, Use of Dihydroxyacetone Phosphate Dependent Aldolases in the Synthesis of Deoxyazasugars, J Org Chem, vol. 56, 6280-6289, 1991
|
| 1991 |
C. H. Wong, T. Krach, C. Gautheron Le Narvor, Y. Ichikawa, G. C. Look, F. Gaeta, D. Thompson, K. C. Nicolaou, Synthesis of novel disaccharides based on glycosyltransferases: [beta]1,4galactosyltransferase, Tetrahedron Lett, vol. 32, 4867-4870, 1991
|
| 1991 |
K. C. Nicolaou, C. W. Hummel, N. J. Bockovich, C. H. Wong, Stereocontrolled Synthesis of Sialyl Lex, the Oligosaccharide Binding Ligand to Elam-1 (Sialyl = N-Acetylneuramin), JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, vol. 13, 870-872, 1991
|
| 1991 |
H. Fu, M. Newcomb, C. H. Wong, Pseudomonas-Oleovorans Monooxygenase Catalyzed Asymmetric Epoxidation of Allyl Alcohol Derivatives and Hydroxylation of a Hypersensitive Radical Probe with the Radical Ring-Opening Rate Exceeding the Oxygen Rebound Rate, J Am Chem Soc, vol. 113, 5878-5880, 1991
|
| 1991 |
C. H. Wong, W. J. Hennen, Process for the enzymatic synthesis of nucleosides, US Patent, vol. #5,075,225, 1991
|
| 1991 |
W. Yuan, Z. Zhong, C. H. Wong, Probing the Inhibition of Leukotriene-A4 Hydrolase Based on Its Aminopeptidase Activity, Bioorg Med Chem Lett, vol. 1, 551-556, 1991
|
| 1991 |
C. H. Wong, Y. Ichikawa, T. Krach, C. Gautheronlenarvor, D. P. Dumas, G. C. Look, Probing the Acceptor Specificity of Beta-1,4-Galactosyltransferase for the Development of Enzymatic-Synthesis of Novel Oligosaccharides, J Am Chem Soc, vol. 113, 8137-8145, 1991
|
| 1991 |
T. Kajimoto, L. R. Chen, K. K. C. Liu, C. H. Wong, Palladium-Mediated Stereocontrolled Reductive Amination of Azido Sugars Prepared from Enzymatic Aldol Condensation - a General-Approach to the Synthesis of Deoxy Aza Sugars, J Am Chem Soc, vol. 113, 6678-6680, 1991
|
| 1991 |
C. F. Barbas, C. H. Wong, Overexpression and Substrate-Specificity Studies of Phosphodeoxyribomutase and Thymidine Phosphorylase, BIOORGANIC CHEMISTRY, vol. 19, 261-269, 1991
|
| 1991 |
C. H. Wong, K. T. Wang, New developments in enzymatic peptide synthesis, EXPERIENTIA, vol. 47, 1123-1129, 1991
|
| 1991 |
C. H. Wong, Microbial aldolases in carbohydrate synthesis, In: Enzymes in carbohydrate synthesis. American Chemical Society Symposium Series, vol. 466, 23-37, 1991
|
| 1991 |
F. Hong, G. C. Look, Z. Wei, E. N. Jacobsen, C. H. Wong, Mechanistic Study of a Synthetically Useful Monooxygenase Model Using the Hypersensitive Probe Trans-2-Phenyl-1-Vinylcyclopropane, J Org Chem, vol. 56, 6497-6500, 1991
|
| 1991 |
C. Gautheronlenarvor, C. H. Wong, Glycosyltransferase-Catalyzed Stereoselective Glycosidation of Monosaccharide-Based Glycosidase Inhibitors - a New Approach to the Synthesis of Sequence-Specific Glycosidase Inhibitors, J Chem Soc Chem Commun, vol. 1130-1131, 1991
|
| 1991 |
K. K. C. Liu, R. L. Pederson, C. H. Wong, Fructose 1,6-Diphosphate Aldolase-Catalyzed Stereoselective C-C Bond Formation, JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, vol. 2669-2673, 1991
|
| 1991 |
Y. Ichikawa, G. J. Shen, C. H. Wong, Enzyme-Catalyzed Synthesis of Sialyl Oligosaccharide with Insitu Regeneration of Cmp-Sialic Acid, J Am Chem Soc, vol. 113, 4698-4700, 1991
|
| 1991 |
C. W. Bradshaw, C. H. Wong, W. Hummel, M. R. Kula, Enzyme-Catalyzed Asymmetric-Synthesis of (S)-2-Amino-4-Phenylbutanoic Acid and (R)-2-Hydroxy-4-Phenylbutanoic Acid, BIOORGANIC CHEMISTRY, vol. 19, 29-39, 1991
|
| 1991 |
T. Kajimoto, K. K. C. Liu, R. L. Pederson, Z. Y. Zhong, Y. Ichikawa, J. A. Porco, C. H. Wong, Enzyme-Catalyzed Aldol Condensation for Asymmetric-Synthesis of Azasugars - Synthesis, Evaluation, and Modeling of Glycosidase Inhibitors, J Am Chem Soc, vol. 113, 6187-6196, 1991
|
| 1991 |
D. G. Drueckhammer, W. J. Hennen, R. L. Pederson, C. F. Barbas, C.M.G. III, T. Krach, C. H. Wong, Enzyme Catalysis in Synthetic Carbohydrate Chemistry, SYNTHESE, vol. 7, 499-525, 1991
|
| 1991 |
D. P. Dumas, Y. Ichikawa, C. H. Wong, J. B. Lowe, R. P. Nair, Enzymatic-Synthesis of Sialyl Lex and Derivatives Based on a Recombinant Fucosyl-Transferase, Bioorg Med Chem Lett, vol. 1, 425-428, 1991
|
| 1991 |
C. H. Wong, G. J. Shen, R. L. Pederson, Y. F. Wang, W. J. Hennen, Enzymatic catalysis in organic synthesis, Methods Enzymol, vol. 202, 591-620, 1991
|
| 1991 |
Z. Y. Zhong, J. L. C. Liu, L. M. Dinterman, M. A. J. Finkelman, W. T. Mueller, M. L. Rollence, M. Whitlow, C. H. Wong, Engineering Subtilisin for Reaction in Dimethylformamide, J Am Chem Soc, vol. 113, 683-684, 1991
|
| 1991 |
Z. Y. Zhong, C. H. Wong, Development of new enzymatic catalysts for peptide synthesis in aqueous and organic solvents, Biomed Biochim Acta, vol. 50, S9-14, 1991
|
| 1991 |
H. Fu, G. J. Shen, C. H. Wong, Asymmetric Epoxidation of Allyl Alcohol Derivatives by Omega-Hydroxylase from Pseudomonas-Oleovorans, Recueil Des Travaux Chimiques Des Pays-Bas-Journal of the Royal Netherlands Chemical Society, vol. 110, 167-170, 1991
|
| 1991 |
R. L. Pederson, J. Esker, C. H. Wong, An improved synthesis of dihydroxyacetone phosphate, Tetrahedron, vol. 47, 2643-2648, 1991
|
| 1991 |
C. H. Wong, Aldolases in synthesis of fluorosugars, In: Selective fluorination in organic and bioorganic chemistry. American Chemical Society Symposium Series, vol. 456, 156-162, 1991
|
| 1991 |
Z. Zhong, J. A. Bibbs, W. Yuan, C. H. Wong, Active-Site-Directed Modification of Subtilisin, J Am Chem Soc, vol. 113, 2259-2263, 1991
|
| 1991 |
C. W. Bradshaw, G. J. Shen, C. H. Wong, A New Alcohol-Dehydrogenase with Unique Stereospecificity from Pseudomonas Sp, BIOORGANIC CHEMISTRY, vol. 19, 398-417, 1991
|
| 1991 |
Y. Ichikawa, J. L. C. Liu, G. J. Shen, C. H. Wong, A Highly Efficient Multienzyme System for the One-Step Synthesis of a Sialyl Trisaccharide - Insitu Generation of Sialic-Acid and N-Acetyllactosamine Coupled with Regeneration of Udp-Glucose, Udp-Galactose, and Cmp-Sialic Acid, J Am Chem Soc, vol. 113, 6300-6302, 1991
|
| 1991 |
C. Gautheronlenarvor, Y. Ichikawa, C. H. Wong, A Complete Change of Stereoselectivity in Sialic-Acid Aldolase Reactions - a Novel Synthetic Route to the Kdo Type of 9-Carbon-L Sugars, J Am Chem Soc, vol. 113, 7816-7818, 1991
|
| 1990 |
K. K. Liu, K. Nozaki, C. H. Wong, Problems of acyl migration in lipase-catalyzed enantioselective transformation of meso-1,3-diol systems, BIOCATALYSIS, vol. 3, 169-177, 1990
|
| 1990 |
J. A. Bibbs, Z. Zhong, C. H. Wong, Modification of protease for peptide synthesis"", in Proceedings of symposium on materials synthesis utilizing biological processes, In: Materials Synthesis Utilizing Biological Processes, vol. 223-228, 1990
|
| 1990 |
S. H. Hsu, S. S. Wu, Wang, Yi Fong, C. H. Wong, Lipase-catalyzed irreversible transesterification using enol esters: XAD-8 immobilized lipoprotein lipase-catalyzed resolution of secondary alcohols, Tetrahedron Lett, vol. 31, 6403-6406, 1990
|
| 1990 |
K. A. Babiak, J. S. Ng, J. H. Dygos, C. L. Weyker, Y. F. Wang, C. H. Wong, Lipase-Catalyzed Irreversible Transesterification Using Enol Esters - Resolution of Prostaglandin Synthons 4-Hydroxy-2-Alkyl-2-Cyclopentenones and Inversion of the 4s Enantiomer to the 4r Enantiomer, J Org Chem, vol. 55, 3377-3381, 1990
|
| 1990 |
C. H. Wong, S. T. Chen, W. J. Hennen, J. A. Bibbs, Y. F. Wang, J. L. C. Liu, M. W. Pantoliano, M. Whitlow, P. N. Bryan, Enzymes in Organic-Synthesis - Use of Subtilisin and a Highly Stable Mutant Derived from Multiple Site-Specific Mutations, J Am Chem Soc, vol. 112, 945-953, 1990
|
| 1990 |
R. L. Pederson, K. K. C. Liu, J. F. Rutan, L. Chen, C. H. Wong, Enzymes in Organic-Synthesis - Synthesis of Highly Enantiomerically Pure 1,2-Epoxy Aldehydes, Epoxy Alcohols, Thiirane, Aziridine, and Glyceraldehyde-3-Phosphate, J Org Chem, vol. 55, 4897-4901, 1990
|
| 1990 |
C. H. Wong, Enzymes in organic synthesis, Chemtracts-Organic Chemistry, vol. 3, 91-111, 1990
|
| 1990 |
J. B. West, W. J. Hennen, J. L. Lalonde, J. A. Bibbs, Z. Y. Zhong, E. F. Meyer, C. H. Wong, Enzymes as Synthetic Catalysts - Mechanistic and Active-Site Considerations of Natural and Modified Chymotrypsin, J Am Chem Soc, vol. 112, 5313-5320, 1990
|
| 1990 |
C. H. Wong, Design and development of enzymatic organic synthesis, In: Chem. Aspects Enzyme Biotech, vol. 165-178, 1990
|
| 1990 |
C. F. Barbas, Y. F. Wang, C. H. Wong, Deoxyribose-5-Phosphate Aldolase as a Synthetic Catalyst, J Am Chem Soc, vol. 112, 2013-2014, 1990
|
| 1990 |
C. H. Wong, Aldolases in organic synthesis, BIOCATALYSIS, vol. 319, 1990
|
| 1990 |
G. J. Shen, Y. F. Wang, C. Bradshaw, C. H. Wong, A New Nad-Dependent Alcohol-Dehydrogenase with Opposite Facial Selectivity Useful for Asymmetric Reduction and Cofactor Regeneration, JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, vol. 677-679, 1990
|
| 1989 |
C. H. Vonderosten, A. J. Sinskey, C. F. Barbas, R. L. Pederson, Y. F. Wang, C. H. Wong, Use of a Recombinant Bacterial Fructose-1,6-Diphosphate Aldolase in Aldol Reactions - Preparative Syntheses of 1-Deoxynojirimycin, 1-Deoxymannojirimycin, 1,4-Dideoxy-1,4-Imino-D-Arabinitol, and Fagomine, J Am Chem Soc, vol. 111, 3924-3927, 1989
|
| 1989 |
S. T. Chen, C. H. Wong, Studies on Angiotensin-Converting Enzyme-Inhibitors - Protease Catalyzed Resolution of Aryl 3-Mercapto-2-Methylpropionic Ester, J Chin Chem Soc, vol. 36, 451-458, 1989
|
| 1989 |
D. G. Drueckhammer, J. R. Durrwachter, R. L. Pederson, D. C. Crans, L. Daniels, C. H. Wong, Reversible and Insitu Formation of Organic Arsenates and Vanadates as Organic Phosphate Mimics in Enzymatic-Reactions - Mechanistic Investigation of Aldol Reactions and Synthetic Applications, J Org Chem, vol. 54, 70-77, 1989
|
| 1989 |
C. H. von der Osten, C. F. Barbas, 3rd, C. H. Wong, A. J. Sinskey, Molecular cloning, nucleotide sequence and fine-structural analysis of the Corynebacterium glutamicum fda gene: structural comparison of C. glutamicum fructose-1,6-biphosphate aldolase to class I and class II aldolases, Mol Microbiol, vol. 3, 1625-1637, 1989
|
| 1989 |
Y. F. Wang, S. T. Chen, K. K. C. Liu, C. H. Wong, Lipase-catalyzed irreversible transesterification using enol esters: Resolution of cyanohydrins and syntheses of ethyl (R)-2-hydroxy-4-phenylbutyrate and (S)-propranolol, Tetrahedron Lett, vol. 30, 1917-1920, 1989
|
| 1989 |
C. H. Wong, Enzymes in organic synthesis: aldol reactions as a route to unusual sugars, In: Bioproducts and Bioprocesses, vol. 147-154, 1989
|
| 1989 |
C. H. Wong, Enzyme-catalyzed synthesis of carbohydrates, Trends in Synthetic Carbohydrate Chemistry, ACS Symposium Series, vol. 386, 317-335, 1989
|
| 1989 |
C. H. Wong, Enzymatic catalysts in organic synthesis, Science, vol. 244, 1145-1152, 1989
|
| 1989 |
R. L. Pederson, C. H. Wong, Enzymatic Aldol Condensation as a Route to Heterocycles - Synthesis of 1,4-Dideoxy-1,4-Imino-D-Arabinitol, Fagomine, 1-Deoxynojirimycin and 1-Deoxymannojirimycin, Heterocycles, vol. 28, 477-480, 1989
|
| 1989 |
Y. F. Wang, C. H. Wong, Enantioselective Syntheses of Platelet-Activating Factor and a Phospholipase-A2 Inhibitor from Chiral Synthons Prepared Enzymatically, J Chin Chem Soc, vol. 36, 463-468, 1989
|
| 1989 |
W. J. Hennen, C. H. Wong, A New Method for the Enzymatic-Synthesis of Nucleosides Using Purine Nucleoside Phosphorylase, J Org Chem, vol. 54, 4692-4695, 1989
|
| 1988 |
I. Barbas, Carlos F., C. H. Wong, One-pot tripeptide syntheses from three single amino acid derivatives catalyzed by papain, Tetrahedron Lett, vol. 29, 2907-2910, 1988
|
| 1988 |
J. B. West, J. Scholten, N. J. Stolowich, J. L. Hogg, A. I. Scott, C. H. Wong, Modification of Proteases to Esterases for Peptide-Synthesis - Methylchymotrypsin, J Am Chem Soc, vol. 110, 3709-3710, 1988
|
| 1988 |
Y. F. Wang, J. J. Lalonde, M. Momongan, D. E. Bergbreiter, C. H. Wong, Lipase-Catalyzed Irreversible Transesterifications Using Enol Esters as Acylating Reagents - Preparative Enantioselective and Regioselective Syntheses of Alcohols, Glycerol Derivatives, Sugars, and Organometallics, J Am Chem Soc, vol. 110, 7200-7205, 1988
|
| 1988 |
Y. F. Wang, C. H. Wong, Lipase-Catalyzed Irreversible Trans-Esterification for Preparative Synthesis of Chiral Glycerol Derivatives, J Org Chem, vol. 53, 3127-3129, 1988
|
| 1988 |
J. R. Durrwachter, C. H. Wong, Fructose 1,6-Diphosphate Aldolase Catalyzed Stereoselective Synthesis of C-Alkyl and N-Containing Sugars - Thermodynamically Controlled C-C Bond Formations, J Org Chem, vol. 53, 4175-4181, 1988
|
| 1988 |
M. J. Kim, W. J. Hennen, H. M. Sweers, C. H. Wong, Enzymes in Carbohydrate Synthesis - N-Acetylneuraminic Acid Aldolase Catalyzed-Reactions and Preparation of N-Acetyl-2-Deoxy-D-Neuraminic Acid-Derivatives, J Am Chem Soc, vol. 110, 6481-6486, 1988
|
| 1988 |
W. J. Hennen, H. M. Sweers, Y. F. Wang, C. H. Wong, Enzymes in Carbohydrate Synthesis - Lipase-Catalyzed Selective Acylation and Deacylation of Furanose and Pyranose Derivatives, J Org Chem, vol. 53, 4939-4945, 1988
|
| 1988 |
J. J. Lalonde, D. E. Bergbreiter, C. H. Wong, Enzymatic Kinetic Resolution of Alpha-Nitro Alpha-Methyl Carboxylic-Acids, J Org Chem, vol. 53, 2323-2327, 1988
|
| 1988 |
D. G. Drueckhammer, C. F. Barbas, K. Nozaki, C. H. Wong, C. Y. Wood, M. A. Ciufolini, Chemoenzymic Synthesis of Chiral Furan-Derivatives - Useful Building-Blocks for Optically-Active Structures, J Org Chem, vol. 53, 1607-1611, 1988
|
| 1988 |
C. H. Wong, D. G. Drueckhammer, H. M. Sweers, Chemoenzymatic synthesis of fluorosugars, ACS Symposium Series on Fluorocarbohydrates: Chemistry and Biochemistry, vol. 29-42, 1988
|
| 1988 |
C. F. Barbas, J. R. Matos, J. B. West, C. H. Wong, A Search for Peptide Ligase - Cosolvent-Mediated Conversion of Proteases to Esterases for Irreversible Synthesis of Peptides, J Am Chem Soc, vol. 110, 5162-5166, 1988
|
| 1988 |
R. L. Pederson, M. J. Kim, C. H. Wong, A combined chemical and enzymatic procedure for the synthesis of 1-deoxynojirimycin and 1-deoxymannojirimycin, Tetrahedron Lett, vol. 29, 4645-4648, 1988
|
| 1987 |
J. B. West, C. H. Wong, Use of nonproteases in peptide synthesis, Tetrahedron Lett, vol. 28, 1629-1632, 1987
|
| 1987 |
J. R. Matos, F. M. Raushel, C. H. Wong, S-adenosylmethionine: studies on chemical and enzymatic synthesis, BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, vol. 9, 39-52, 1987
|
| 1987 |
J. R. Matos, C. H. Wong, S-Adenosylmethionine - Stability and Stabilization, BIOORGANIC CHEMISTRY, vol. 15, 71-80, 1987
|
| 1987 |
C. F. Barbas, C. H. Wong, Papain Catalyzed Peptide-Synthesis - Control of Amidase Activity and the Introduction of Unusual Amino-Acids, JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, vol. 533-534, 1987
|
| 1987 |
J. R. Matos, J. B. West, C. H. Wong, Lipase Catalyzed Synthesis of Peptides - Preparation of a Penicillin-G Precursor and Other Peptides, BIOTECHNOLOGY LETTERS, vol. 9, 233-236, 1987
|
| 1987 |
D. C. Crans, R. J. Kazlauskas, B. L. Hirschbein, C. H. Wong, O. Abril, G. M. Whitesides, Enzymatic regeneration of adenosine 5'-triphosphate: acetyl phosphate, phosphoenolpyruvate, methoxycarbonyl phosphate, dihydroxyacetone phosphate, 5-phospho-alpha-D-ribosyl pyrophosphate, uridine-5'-diphosphoglucose, Methods Enzymol, vol. 136, 263-280, 1987
|
| 1987 |
D. G. Drueckhammer, S. K. Sadozai, C. H. Wong, S. M. Roberts, Biphasic One-Pot Synthesis of 2 Useful and Separable Compounds Using Nicotinamide Cofactor-Requiring Enzymes - Syntheses of (S)-4-Hydroxyhexanoate and Its Lactone, Enzyme Microb Technol, vol. 9, 564-570, 1987
|
| 1986 |
C. H. Wong, Nicotinamide cofactor-requiring enzymatic synthesis in organic solvent-water biphasic systems, Biocatalysis in Organic Media, vol. 197-208, 1986
|
| 1986 |
C. H. Wong, Enzyme-catalyzed synthesis of unusual carbohydrates and peptides, Proceeding of 5th International Symposium on Life Science: Prospects for Enzyme Technology, vol. 86-89, 1986
|
| 1986 |
J. B. West, C. H. Wong, Enzyme-Catalyzed Synthesis of Peptides Containing D-Amino Acids, JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, vol. 417-418, 1986
|
| 1986 |
H. M. Sweers, C. H. Wong, Enzyme-Catalyzed Regioselective Deacylation of Protected Sugars in Carbohydrate Synthesis, J Am Chem Soc, vol. 108, 6421-6422, 1986
|
| 1986 |
J. B. West, C. H. Wong, Enzyme-Catalyzed Irreversible Formation of Peptides Containing D-Amino Acids, J Org Chem, vol. 51, 2728-2735, 1986
|
| 1986 |
C. H. Wong, J. B. West, Enzymatic-Synthesis of Peptides Containing D-Amino Acids, FEDERATION PROCEEDINGS, vol. 45, 1789-1789, 1986
|
| 1986 |
J. R. Durrwachter, H. M. Sweers, K. Nozaki, C. H. Wong, Enzymatic aldol reaction/isomerization as a route to unusual sugars, Tetrahedron Lett, vol. 27, 1261-1264, 1986
|
| 1986 |
J. R. Durrwachter, D. G. Drueckhammer, K. Nozaki, H. M. Sweers, C. H. Wong, Enzymatic Aldol Condensation Isomerization as a Route to Unusual Sugar-Derivatives, J Am Chem Soc, vol. 108, 7812-7818, 1986
|
| 1986 |
S. T. Chen, K. T. Wang, C. H. Wong, Chirally Selective Hydrolysis of D,L-Amino Acid-Esters by Alkaline Protease, JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, vol. 1514-1516, 1986
|
| 1986 |
J. R. Matos, C. H. Wong, Biphasic One-Pot Synthesis of 2 Useful and Separable Compounds Using Cofactor-Requiring Enzymatic-Reactions - Glutamate-Dehydrogenase Catalyzed Synthesis of L-Alpha-Aminoadipate Coupled with Alcohol-Dehydrogenase Catalyzed Synthesis of a Chiral Lactone, J Org Chem, vol. 51, 2388-2389, 1986
|
| 1986 |
C. H. Wong, Aldolases as catalysts in organic synthesis, In: Enzymes as Catalysts in Organic Synthesis, vol. 199-216, 1986
|
| 1985 |
D. G. Drueckhammer, V. W. Riddle, C. H. Wong, Fmn Reductase Catalyzed Regeneration of Nad(P) for Use in Enzymatic-Synthesis, J Org Chem, vol. 50, 5387-5389, 1985
|
| 1985 |
C. H. Wong, Enzymes in organic synthesis: aldol condensation, Industrial Chemical News, vol. 6, 24-25, 1985
|
| 1985 |
G. M. Whitesides, C. H. Wong, Enzymes as Catalysts in Synthetic Organic Chemistry, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 24, 617-638, 1985
|
| 1985 |
R. L. Root, J. R. Durrwachter, C. H. Wong, Enzymatic-Synthesis of Unusual Sugars - Galactose-Oxidase Catalyzed Stereospecific Oxidation of Polyols, J Am Chem Soc, vol. 107, 2997-2999, 1985
|
| 1985 |
C. H. Wong, D. G. Drueckhammer, H. M. Sweers, Enzymatic Vs Fermentative Synthesis - Thermostable Glucose-Dehydrogenase Catalyzed Regeneration of Nad(P)H for Use in Enzymatic-Synthesis, J Am Chem Soc, vol. 107, 4028-4031, 1985
|
| 1985 |
C. H. Wong, D. G. Drueckhammer, Enzymatic synthesis of chiral hydroxy compounds using immobilized glucose dehydrogenase from Bacillus cereus for NAD(P)H regeneration, NATURE BIOTECHNOLOGY, vol. 3, 649-651, 1985
|
| 1985 |
J. R. Matos, M. B. Smith, C. H. Wong, Enantioselectivity of Alcohol Dehydrogenase-Catalyzed Oxidation of 1,2-Diols and Aminoalcohols, BIOORGANIC CHEMISTRY, vol. 13, 121-130, 1985
|
| 1985 |
C. H. Wong, J. R. Matos, Enantioselective Oxidation of 1,2-Diols to L-Alpha-Hydroxy Acids Using Coimmobilized Alcohol and Aldehyde Dehydrogenases as Catalysts, J Org Chem, vol. 50, 1992-1994, 1985
|
| 1985 |
D. G. Drueckhammer, C. H. Wong, Chemoenzymatic Syntheses of Fluoro Sugar Phosphates and Analogs, J Org Chem, vol. 50, 5912-5913, 1985
|
| 1984 |
G.M. Whitesides, P.F. Mazenod, C. H. Wong, Preparation of 6-Deoxy-d-Fructose and 6-deoxy-L-Sorbose, US Patent, vol. #4,440,854, 1984
|
| 1983 |
C. H. Wong, G. M. Whitesides, Synthesis of Sugars by Aldolase-Catalyzed Condensation-Reactions, J Org Chem, vol. 48, 3199-3205, 1983
|
| 1983 |
C. H. Wong, S. L. Haynie, G. M. Whitesides, Preparation of a Mixture of Nucleoside Triphosphates from Yeast Rna - Use in Enzymatic-Synthesis Requiring Nucleoside Triphosphate Regeneration and Conversion to Nucleoside Diphosphate Sugars, J Am Chem Soc, vol. 105, 115-117, 1983
|
| 1983 |
G. M. Whitesides, C. H. Wong, Enzymes as catalysts in organic synthesis, Aldrichimica Acta, vol. 16, 27-34, 1983
|
| 1983 |
C. H. Wong, G. M. Whitesides, Enzyme-Catalyzed Organic-Synthesis - Regeneration of Deuterated Nicotinamide Cofactors for Use in Large-Scale Enzymatic-Synthesis of Deuterated Substances, J Am Chem Soc, vol. 105, 5012-5014, 1983
|
| 1983 |
C. H. Wong, F. P. Mazenod, G. M. Whitesides, Chemical and Enzymatic Syntheses of 6-Deoxyhexoses - Conversion to 2,5-Dimethyl-4-Hydroxy-2,3-Dihydrofuran-3-One (Furaneol) and Analogs, J Org Chem, vol. 48, 3493-3497, 1983
|
| 1982 |
C. H. Wong, A. Pollak, S. D. McCurry, J. M. Sue, J. R. Knowles, G. M. Whitesides, Synthesis of ribulose 1,5-bisphosphate: routes from glucose 6-phosphate (via 6-phosphogluconate) and from adenosine monophosphate (via ribose 5-phosphate), Methods Enzymol, vol. 89 Pt D, 108-121, 1982
|
| 1982 |
C. H. Wong, Enzymes as catalysts in organic synthesis, Ph.D. Dissertation, Massachusetts Institute of Technology, 1982
|
| 1982 |
C. H. Wong, G. M. Whitesides, Enzyme-Catalyzed Transhydrogenation between Nicotinamide Cofactors and Its Application in Organic-Synthesis, J Am Chem Soc, vol. 104, 3542-3544, 1982
|
| 1982 |
C. H. Wong, S. L. Haynie, G. M. Whitesides, Enzyme-Catalyzed Synthesis of N-Acetyllactosamine with Insitu Regeneration of Uridine 5'-Diphosphate Glucose and Uridine 5'-Diphosphate Galactose, J Org Chem, vol. 47, 5416-5418, 1982
|
| 1982 |
C. H. Wong, G. M. Whitesides, Enzyme-Catalyzed Organic-Synthesis - Nad(P)H Cofactor Regeneration Using Ethanol Alcohol-Dehydrogenase Aldehyde Dehydrogenase and Methanol Alcohol-Dehydrogenase Aldehyde Dehydrogenase Formate Dehydrogenase, J Org Chem, vol. 47, 2816-2818, 1982
|
| 1982 |
G. M. Whitesides, C. M. Wong, A. Pollak, Asymmetric synthesis using cofactor-requiring enzymes, Asymmetric Reactions and Processes in Chemistry, vol. 185, 205-218, 1982
|
| 1981 |
C. H. Wong, J. Gordon, C. L. Cooney, G. M. Whitesides, Regeneration of Nad(P)H Using Glucose 6-Sulfate and Glucose-6-Phosphate-Dehydrogenase, J Org Chem, vol. 46, 4676-4679, 1981
|
| 1981 |
C. H. Wong, L. Daniels, W. H. Ormejohnson, G. M. Whitesides, Enzyme-Catalyzed Organic-Synthesis - Nad(P)H Regeneration Using Dihydrogen and the Hydrogenase from Methanobacterium-Thermoautotrophicum, J Am Chem Soc, vol. 103, 6227-6228, 1981
|
| 1981 |
C. H. Wong, G. M. Whitesides, Enzyme-Catalyzed Organic-Synthesis - Nad(P)H Cofactor Regeneration by Using Glucose-6-Phosphate and the Glucose-6-Phosphate-Dehydrogenase from Leuconostoc-Mesenteroides, J Am Chem Soc, vol. 103, 4890-4899, 1981
|
| 1981 |
R. Dicosimo, C. H. Wong, L. Daniels, G. M. Whitesides, Enzyme-Catalyzed Organic-Synthesis - Electrochemical Regeneration of Nad(P)H from Nad(P) Using Methyl Viologen and Flavoenzymes, J Org Chem, vol. 46, 4622-4623, 1981
|
| 1980 |
C. H. Wong, S. D. McCurry, G. M. Whitesides, Practical Enzymatic Syntheses of Ribulose 1,5-Bisphosphate and Ribose 5-Phosphate, J Am Chem Soc, vol. 102, 7938-7939, 1980
|
| 1979 |
C. H. Wong, Resolution of Rs-Mandelic Acid, J Chin Chem Soc, vol. 26, 75-78, 1979
|
| 1979 |
C. H. Wong, S. T. Chen, K. T. Wang, Enzymic synthesis of opioid peptides, BIOCHIMICA ET BIOPHYSICA ACTA, vol. 576, 247-249, 1979
|
| 1979 |
S. H. Chou, C. H. Wong, S. T. Chen, K. T. Wang, Enzymatic-Synthesis of Oligopeptide .2. Synthesis of Bis-(N-Protected Amino-Acid) Hydrazides by Papain, J Chin Chem Soc, vol. 26, 11-15, 1979
|
| 1978 |
C. H. Wong, S. W. Chen, C. L. Ho, K. T. Wang, Synthesis of cobra neurotoxin, Proc Natl Sci Council ROC, vol. 2, 149-153, 1978
|
| 1978 |
C. H. Wong, S. T. Chen, C. L. Ho, K. T. Wang, Synthesis of a fully active snake venom cardiotoxin by fragment condensation on solid polymer, BIOCHIMICA ET BIOPHYSICA ACTA, vol. 536, 376-389, 1978
|
| 1978 |
C. H. Wong, Y. H. Chen, M. C. Hung, K. T. Wang, C. L. Ho, T. B. Lo, Renaturation of a reduced Taiwan cobra cardiotoxin, BIOCHIMICA ET BIOPHYSICA ACTA, vol. 533, 105-111, 1978
|
| 1978 |
C. H. Wong, C. L. Ho, K. T. Wang, Purfication of synthetic cardiotoxin by affinity chromatography, JOURNAL OF CHROMATOGRAPHY, vol. 154, 13-23, 1978
|
| 1978 |
C. H. Wong, M. F. Ho, K. T. Wang, Preparation of Optically Pure N-Tert-Butyloxycarbonyl-O-Benzyl-L-Serine and Its Antipode, J Org Chem, vol. 43, 3604-3604, 1978
|
| 1978 |
C. H. Wong, K. T. Wang, Mutual Resolution of Dl-Ephedrine and N-Benzyloxycarbonyl-Dl-Amino Acids, J Chin Chem Soc, vol. 25, 209-214, 1978
|
| 1978 |
C. H. Wong, K. T. Wang, Mutual resolution of (+/-)-ephedrine and Z-DL-amino acid induced by seeding chiral salt, Tetrahedron Lett, vol. 19, 3813-3816, 1978
|
| 1978 |
S. H. Chou, S. T. Chen, C. H. Wong, K. T. Wang, Enzymatic-Synthesis of Oligopeptide .1. Papain-Catalyzed Synthesis of Dipeptide, Tripeptide and Tetrapeptide, J Chin Chem Soc, vol. 25, 215-218, 1978
|
| 1978 |
C. H. Wong, K. T. Wang, Electrochemistry in Organic-Synthesis .1. Large-Scale Preparation of Cysteine from Cystine, J Chin Chem Soc, vol. 25, 149-151, 1978
|
| 1977 |
C. H. Wong, S. T. Chen, K. T. Wang, Resolution of Amino-Acids by Enzymes .1. Proteolytic-Enzyme Bromelain for Hydrolysis of L-Amino-Acid Methyl-Esters, J Chin Chem Soc, vol. 24, 129-133, 1977
|
| 1976 |
F. T. Kong, T. C. Lin, C. H. Wong, K. T. Wang, Synthesis of Taiwan Cobra Venom Cardiotoxin .2. Synthesis of Protected Hexapeptide, Sequence 44-49 and Protected Tripeptide, Sequence 50-52, J Chin Chem Soc, vol. 23, 155-164, 1976
|