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專任研究助理
馬徹老師實驗室 / Alex Ma Lab at GRC【工作內容 / Responsibilities】
本實驗室的研究重點為傳染病及癌症新藥研發,利用結構生物學的技術(X光結晶學,低溫電子顯微鏡)探討新冠肺炎、流感、抗藥性細菌感染以及癌細胞之膜蛋白及醣蛋白結構,作為新藥研發的基礎。
1、藉由分析蛋白質的立體空間結構,作為新藥設計的基礎。
2、運用細胞及動物實驗模型,探討新型藥物之廣度及效能。
My lab foucuses on structural biology and drug discovery in infectious diseases and cancers. X-ray crystallography and cryo-EM are being used to study membrane proteins and glycoproteins in SARS=COV-2, influenza viruses, drug-resistant bacteria and cancers, to provide structural basis for drug-discovery and vaccine design. In vitro cell based assays and in vivo animal models are being used to validate the efficacy of novel vaccines.

