Selected Publications

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Year Paper Title
2000 C. Saotome, Y. Kanie, O. Kanie, C. H. Wong, Synthesis and enzymatic evaluation of five-membered iminocyclitols and a pseudodisaccharide, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, 2249-2261, 2000
2000 X. L. Sun, Y. Kanie, C. T. Guo, O. Kanie, Y. Suzuki, C. H. Wong, Syntheses of C-3-modified sialylglycosides as selective inhibitors of influenza hemagglutinin and neuraminidase, Eur J Org Chem, vol. 2643-2653, 2000
2000 M. Li, G. M. Morris, T. Lee, G. S. Laco, C. H. Wong, A. J. Olson, J. H. Elder, A. Wlodawer, A. Gustchina, Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease, Proteins, vol. 38, 29-40, 2000
2000 S. J. Sucheck, C. H. Wong, RNA as a target for small molecules, Curr Opin Chem Biol, vol. 4, 678-686, 2000
2000 O. Kanie, G. Grotenbreg, C. H. Wong, Removal of Benzyl Protecting Groups from Solid-Supported Compounds by Hydrogenolysis Using Palladium Nanoparticles, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 39, 4545-4547, 2000
2000 M. D. Burkart, M. Izumi, E. Chapman, C. H. Lin, C. H. Wong, Regeneration of PAPS for the enzymatic synthesis of sulfated oligosaccharides, J Org Chem, vol. 65, 5565-5574, 2000
2000 K. M. Koeller, C. H. Wong, Recycling of sugar nucleotides in enzymatic glycosylation, In: Carbohydrates in Chemistry and Biology, vol. 663-684, 2000
2000 T. L. Sheppard, C. H. Wong, G. F. Joyce, Nucleoglycoconjugates: design and synthesis of a new class of DNA-carbohydrate conjugates, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 39, 3660-3663, 2000
2000 C. H. Wong, M. Hendrix, P. Alper, S. Priestley, Nucleic acid binders having an hydroxyamine motif, US Patent, vol. #6,120,997, 2000
2000 C. H. Wong, Method for synthesizing 2-ketoaldonic acids, US Patent, vol. #6,080,563, 2000
2000 C. H. Wong, C. H. Lin, Ketoaldonic acids having formed stereogenic centers of R configuration: Methods and Compositions, US Patent, vol. #6,353,095, 2000
2000 T. J. Tolbert, C. H. Wong, Intein-mediated synthesis of proteins containing carbohydrates and other molecular probes, J Am Chem Soc, vol. 122, 5421-5428, 2000
2000 Z. Zhang, C. H. Wong, Glycosylation methods: use of phosphites, In: Carbohydrates in Chemistry and Biology, vol. 117-134, 2000
2000 K. D. Kreutter, C. H. Wong, Enzyme inhibitors, In: Stimulating Concepts in Chemistry, vol. 356-368, 2000
2000 K. M. Koeller, C. H. Wong, Emerging themes in medicinal glycoscience, Nat Biotechnol, vol. 18, 835-841, 2000
2000 T. Flessner, C. H. Wong, Efficient synthesis of triazoles from -arabinose and -fucose, Tetrahedron Lett, vol. 41, 7805-7808, 2000
2000 S. Fong, T. D. Machajewski, C. C. Mak, C. H. Wong, Directed evolution of D-2-keto-3-deoxy-6-phosphogluconate aldolase to new variants for the efficient synthesis of D- and L-sugars, Chem Biol, vol. 7, 873-883, 2000
2000 S. J. Sucheck, W. A. Greenberg, T. J. Tolbert, C. H. Wong, Design of Small Molecules That Recognize RNA: Development of Aminoglycosides as Potential Antitumor Agents That Target Oncogenic RNA Sequences, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 39, 1080-1084, 2000
2000 S. J. Sucheck, A. L. Wong, K. M. Koeller, D. D. Boehr, K. Draker, P. Sears, G. D. Wright, C. H. Wong, Design of bifunctional antibiotics that target bacterial rRNA and inhibit resistance-causing enzymes, J Am Chem Soc, vol. 122, 5230-5231, 2000
2000 C. Y. Tsai, X. Huang, C. H. Wong, Design and synthesis of cyclic sialyl Lewis X mimetics: a remarkable enhancement of inhibition by pre-organizing all essential functional groups, Tetrahedron Lett, vol. 41, 9499-9503, 2000
2000 K. M. Koeller, C. H. Wong, Complex carbohydrate synthesis tools for glycobiologists: enzyme-based approach and programmable one-pot strategies, Glycobiology, vol. 10, 1157-1169, 2000
2000 K. M. Koeller, C. H. Wong, Chemoenzymatic synthesis of sialyl-trimeric-Lewis x, CHEMISTRY-A EUROPEAN JOURNAL, vol. 6, 1243-1251, 2000
2000 K. M. Koeller, M. E. Smith, C. H. Wong, Chemoenzymatic synthesis of PSGL-1 glycopeptides: sulfation on tyrosine affects glycosyltransferase-catalyzed synthesis of the O-glycan, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, 1017-1025, 2000
2000 A. Duffels, L. G. Green, R. Lenz, S. V. Ley, S. P. Vincent, C. H. Wong, Chemoenzymatic synthesis of L-galactosylated dimeric sialyl Lewis X structures employing alpha-1,3-fucosyltransferase V, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, 2519-2525, 2000
2000 K. M. Koeller, M. E. B. Smith, R. F. Huang, C. H. Wong, Chemoenzymatic synthesis of a PSGL-1 N-terminal glycopeptide containing tyrosine sulfate and alpha-O-linked sialyl Lewis X, J Am Chem Soc, vol. 122, 4241-4242, 2000
2000 V. Wittmann, A. K. Datta, K. M. Koeller, C. H. Wong, Chemoenzymatic synthesis and fluorescent visualization of cell-surface selectin-bound sialyl Lewis x derivatives, CHEMISTRY-A EUROPEAN JOURNAL, vol. 6, 162-171, 2000
2000 A. Romero, C. H. Wong, Chemo-enzymatic total synthesis of 3-epiaustraline, australine, and 7-epialexine, J Org Chem, vol. 65, 8264-8268, 2000
2000 M. D. Burkart, S. P. Vincent, A. Duffels, B. W. Murray, S. V. Ley, C. H. Wong, Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic probes for glycosyltransferases, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, 1937-1946, 2000
2000 S. P. Vincent, A. Schleyer, C. H. Wong, Asymmetric Strecker synthesis of C-glycopeptide, J Org Chem, vol. 65, 4440-4443, 2000
2000 X. S. Ye, C. H. Wong, Anomeric reactivity-based one-pot oligosaccharide synthesis: a rapid route to oligosaccharide libraries, J Org Chem, vol. 65, 2410-2431, 2000