Selected Publications

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Year Paper Title
2002 Y. J. Zhang, S. Y. Chen, C. J. Chen, R. M. Santella*, Polymorphisms of the cyclin D1 gene in hepatocellular carcinoma, Mol Carcinogen, vol. 33, 125-129, 2002
2002 S. Y. Chen, L. Y. Wang, R. M. Lunn, W. Y. Tsai, P. H. Lee, C. S. Lee, H. Ahsan, Y. J. Zhang, C. J. Chen, R. M. Santella*, Polycyclic aromatic hydrocarbons-DNA adducts in liver tissues of hepatocellular carcinoma patients and controls, Int J Cancer, vol. 99, 14-21, 2002
2002 C. J. Chen*, Molecular epidemiological studies of major cancers in Taiwan, J Med Sci, vol. 22, S1-S10, 2002
2002 C. J. Chen*, D. S. Chen, Interaction of hepatitis B virus, chemical carcinogen and genetic susceptibility: Multistage hepatocarcinogenesis with multifactorial etiology, Hepatology, vol. 36, 1046-1049, 2002
2002 C. J. Chiu, M. L. Chang, C. P. Chiang, L. J. Hahn, L. L. Hsieh, C. J. Chen*, Interaction of collagen-related genes and susceptibility to betel quid-induced oral submucous fibrosis, Cancer Epidemiol Biomarkers Prev, vol. 11, 646-653, 2002
2002 M. W. Yu*, H. C. Chang, P. J. Chen, C. J. Liu, Y. F. Liaw, S. M. Lin, S. D. Lee, S. C. Lin, C. L. Lin, C. J. Chen, Increased risk of hepatitis B-related liver cirrhosis in relatives of patients with hepatocellular carcinoma in northern Taiwan, Int J Epidemiol, vol. 31, 1008-1015, 2002
2002 Y. H. Liu, C. L. Du, C. T. Lin, C. C. Chan, C. J. Chen, J. D. Wang*, Increased morbidity from nasopharyngeal carcinoma and chronic pharyngitis or sinusitis among workers at a newspaper printing company, Occup Environ Med, vol. 59, 18-22, 2002
2002 Y. J. Zhang, H. Ahsan, Chen Y, R. M. Lunn, L. Y. Wang, S. Y. Chen, P. H. Lee, C. J. Chen, R. M. Santella*, High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinomas, Mol Carcinogen, vol. 35, 85-92, 2002
2002 H. I. Yang, S. N. Lu, S. L. You, C. A. Sun, L. Y. Wang, K. Hsiao, P. J. Chen, D. S. Chen, Y. F. Liaw, C. J. Chen*, Hepatitis B e antigens and the risk of hepatocellular carcinoma, New Engl J Med, vol. 347, 168-174, 2002
2002 C. J. Chen*, H. I. Yang, S. L. You, Hepatitis B e antigen and hepatocellular carcinoma (letter), New Engl J Med, vol. 347, 1722, 2002
2002 M. S. Wu, C. J. Chen, M. T. Lin, H. P. Wang, C. T. Shun, J. C. Sheu, J. T. Lin*, Genetic polymorphisms of cytochrome P450 2E1, glutathione S-transferase M1 and T1, and susceptibility to gastric carcinoma in Taiwan, Int J Colorectal Dis, vol. 17, 338-343, 2002
2002 C. H. Tseng*, C. P. Tseng, H. Y. Chiou, Y. M. Hsueh, C. K. Chong, C. J. Chen, Epidemiologic evidence of diabetogenic effect of arsenic, Toxicol Lett, vol. 133, 69-76, 2002
2002 C. A. Sun*, D. M. Wu, L. Y. Wang, C. J. Chen, S. L. You, R. M. Santella, Determinants of the formation of aflatoxin-albumin adducts: a seven-township study in Taiwan, Brit J Cancer, vol. 87, 966-970, 2002
2002 H. H. Lin, L. Y. Wang*, C. K. Shaw, M. L. Cheng, W. K. Chung, H. J. Chiang, T. Y. Lin, C. J. Chen, Combined effects of chronic hepatitis virus infections and substance-use habits on chronic liver diseases in Taiwanese aborigines, J Formos Med Assoc, vol. 101, 826-834, 2002
2002 C. J. Chen*, S. L. You, L. H. Lin, W. L. Hsu, Y. W. Yang, Cancer epidemiology and control in Taiwan: a brief review, Jpn J Clin Oncol, vol. 32 Suppl, S66-S81, 2002
2002 C. H. Wang, J. S. Jeng, P. K. Yip, C. L. Chen, L. I. Hsu, Y. M. Hsueh, H. Y. Chiou, M. M. Wu, C. J. Chen*, Biological gradient between long-term arsenic exposure and carotid atherosclerosis, Circulation, vol. 105, 1804-1809, 2002
2002 M. S. Wu, S. P. Huang, Y. T. Chang, M. T. Lin, C. T. Shun, M. C. Chang, H. P. Wang, C. J. Chen, J. T. Lin*, Association of the -160 CA promoter polymorphism of E-Cadherin gene with gastric carcinoma risk, Cancer, vol. 94, 1443-1448, 2002
2002 A. Hildesheim*, R. J. Apple, C. J. Chen, S. S. Wang, Y. C. Cheng, W. Klitz, S. J. Mack, I. H. Chen, M. M. Hsu, C. S. Yang, L. A. Brinton, P. H. Levine, H. A. Erlich, Association of HLA class I and II alleles and extended haplotypes with nasopharyngeal carcinoma in Taiwan, J Natl Cancer Inst, vol. 94, 1780-1789, 2002
2002 M. W. Yu*, Y. C. Yang, S. Y. Yang, H. C. Chang, Y. F. Liaw, S. M. Lin, C. J. Liu, S. D. Lee, C. L. Lin, P. J. Chen, S. C. Lin, C. J. Chen, Androgen receptor exon 1 CAG repeat length and risk of hepatocellular carcinoma in women, Hepatology, vol. 36, 156-163, 2002
2002 C. J. Chiu, W. C. Lee, C. P. Chiang, L. J. Hahn, Y. S. Kuo, C. J. Chen*, A scoring system for the early detection of oral submucous fibrosis based on a self-administered questionnaire, J Public Health Dent, vol. 62, 28-31, 2002
2001 B. Buhler, Y. C. Lin, G. Morris, A. J. Olson, C. H. Wong, D. D. Richman, J. H. Elder, B. E. Torbett, Viral evolution in response to the broad-based retroviral protease inhibitor TL-3, J Virol, vol. 75, 9502-9508, 2001
2001 P. Sears, C. H. Wong, Toward automated synthesis of oligosaccharides and glycoproteins, Science, vol. 291, 2344-2350, 2001
2001 C. S. Yu, K. Niikura, C. C. Lin, C. H. Wong, The Thioglycoside and Glycosyl Phosphite of 5-Azido Sialic Acid: Excellent Donors for the alpha-Glycosylation of Primary Hydroxy Groups This research was supported by Academia Sinica (Taipei) and the NIH (USA), ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 40, 2900-2903, 2001
2001 F. Burkhart, Z. Y. Zhang, S. Wacowich Sgarbi, C. H. Wong, Synthesis of the Globo H hexasaccharide using the programmable reactivity-based one-pot strategy ( This research was supported by the National Institutes of Health. F.B. thanks the Deutsche Forschungsgemeinschaft for a fellowship), ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 40, 1274-1277, 2001
2001 I. A. Kozlov, S. Mao, Y. Xu, X. Huang, L. Lee, P. S. Sears, C. Gao, A. R. Coyle, K. D. Janda, C. H. Wong, Synthesis of solid-supported mirror-image sugars: a novel method for selecting receptors for cellular-surface carbohydrates, Chembiochem, vol. 2, 741-746, 2001
2001 T. K. Ritter, C. H. Wong, Synthesis of N-acetylglucosamine thiazoline/lipid II hybrids, Tetrahedron Lett, vol. 42, 615-618, 2001
2001 V. D. Le, C. C. Mak, Y. C. Lin, J. H. Elder, C. H. Wong, Structure-activity studies of FIV and HIV protease inhibitors containing allophenylnorstatine, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 9, 1185-1195, 2001
2001 C. H. Wong, Y. Ichikawa, G. J. Shen, Production of fucosylated carbohydrates by enzymatic fucosylation; synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose, US Patent, vol. #6,319,695, 2001
2001 M. G. Silvestri, C. H. Wong, Opening of thiiranes: preparation of orthogonal protected 2-thioglyceraldehyde, J Org Chem, vol. 66, 910-914, 2001
2001 A. Heine, G. DeSantis, J. G. Luz, M. Mitchell, C. H. Wong, I. A. Wilson, Observation of covalent intermediates in an enzyme mechanism at atomic resolution, Science, vol. 294, 369-374, 2001