Selected Publications

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Year Paper Title
2005 G. W. Xing, D. Wu, M. A. Poles, A. Horowitz, M. Tsuji, D. D. Ho, C. H. Wong, Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides, Bioorganic & medicinal chemistry, vol. 13, 2907-2916, 2005
2005 Zajonc DM, Maricic I, Wu D, Halder R, Roy K, Wong CH, Kumar V, Wilson IA, Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity., The Journal of experimental medicine, vol. 202(11), 1517-26, 2005
2005 S. H. Wei, H. Rosen, M. P. Matheu, M. G. Sanna, S. K. Wang, E. Jo, C. H. Wong, I. Parker, M. D. Cahalan, Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses, Nat Immunol, vol. 6, 1228-1235, 2005
2005 Y. Kinjo, D. Wu, G. Kim, G. W. Xing, M. A. Poles, D. D. Ho, M. Tsuji, K. Kawahara, C. H. Wong, M. Kronenberg, Recognition of bacterial glycosphingolipids by natural killer T cells, Nature, vol. 434, 520-525, 2005
2005 Sinchaikul, S., Pan, F. M., Cheng, C. W., Wong, C. H., Fang, J. M., Tseng, M. J., Chen, S. T., Protein microarray using alpha-amino acids as metal tags on chips., Bioorg Med Chem Lett, vol. 15(5), 1413-1416, 2005
2005 C. H. Wong, Protein glycosylation: new challenges and opportunities, J Org Chem, vol. 70, 4219-4225, 2005
2005 J. J. Shie, J. M. Fang, T. H. Kuo, C. J. Kuo, P. H. Liang, H. J. Huang, Y. T. Wu, J. T. Jan, Y. S.E. Cheng, C. H. Wong, Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters., Bioorganic & medicinal chemistry, vol. 13, 5240–5252, 2005
2005 M. M. Numa, L. V. Lee, C. C. Hsu, K. E. Bower, C. H. Wong, Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ, Chembiochem, vol. 6, 1002-1006, 2005
2005 Sawkar AR, Adamski-Werner SL, Cheng WC, Wong CH, Beutler E, Zimmer KP, Kelly JW, Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles., Chemistry & biology, vol. 12(11), 1235-44, 2005
2005 A.R. Sawkar, S.L. Adamski-Werner, W.-C. Cheng, C.-H. Wong, E. Beutler, K.-P. Zimmer, J.W. Kelly, Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles, Chem. Biol, vol. 12(11), 1235–1244, 2005
2005 M. Fridman, V. Belakhov, L. V. Lee, F. S. Liang, C. H. Wong, T. Baasov, Dual effect of synthetic aminoglycosides: antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor, Angewandte chemie-international edition, vol. 44, 447-452, 2005
2005 D. A. Calarese, H. K. Lee, C. Y. Huang, M. D. Best, R. D. Astronomo, R. L. Stanfield, H. Katinger, D. R. Burton, C. H. Wong, I. A. Wilson, Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 13372–13377, 2005
2005 J. J. Shie, J. M. Fang, C. J. Kuo, T. H. Kuo, P. H. Liang, H. J. Huang, W. B. Yang, C. H. Lin, J. L. Chen, Y. T. Wu, C. H. Wong, Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease, J Med Chem, vol. 48, 4469-4473, 2005
2005 C.-C. Hsu, Y. Zhang, M. Wada, D. Franke, C.-H. Wong, Directed evolution of d-sialic acid aldolase l-3-deoxy-manno-2-octulosonic acid (l-KDO) aldolases, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 9122-9126, 2005
2005 C. C. Hsu, Y. Zhang, M. Wada, D. Franke, C. H. Wong, Directed evolution of D-sialic acid aldolase L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolases, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 9122–9126, 2005
2005 D. Wu, G. W. Xing, M. A. Poles, A. Horowitz, Y. Kinjo, B. Sullivan, V. Bodmer Narkevitch, O. Plettenburg, M. Kronenberg, M. Tsuji, D. D. Ho, C. H. Wong, Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 102, 1351-1356, 2005
2005 Scanlan C, Calarese D, Lee HK, Blixt O, Wong CH, Wilson I, Burton D, Dwek R, Rudd P, Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design., Advances in experimental medicine and biology, vol. 564, 7-8, 2005
2005 T. J. Tolbert, D. Franke, C. H. Wong, A new strategy for glycoprotein synthesis: ligation of synthetic glycopeptides with truncated proteins expressed in E. coli as TEV protease cleavable fusion protein, Bioorganic & medicinal chemistry, vol. 13, 909-915, 2005
2005 H. N. Yu, D. A. Thayer, M. C. Galan, C. H. Wong, A general strategy toward S-linked glycopeptides, Angewandte chemie-international edition, vol. 44, 4596-4599, 2005
2005 A. Brik, J. Alexandratos, Y. C. Lin, J. H. Elder, A. J. Olson, A. Wlodawer, D. S. Goodsell, C. H. Wong, 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors, Chembiochem, vol. 6, 1167-1169, 2005
2005 T.K.Tang, P.J. Mark, S.T. Chen, M.H. Hou, M.H. Hong, F.M. Pan, H.M.Yu, J.H. Chen, C.W.Yao, A.H.J.Wang, Biochemical and immunological studies of nucleocapsid proteins of severee acute respiratory syndrome and 229E human coronaviruses, Proteomics, vol. 5(4), 925-937, 2005
2005 C. H. Lin, H. C. Lin, W. B. Yang, exo-Glycal Chemistry: General Aspects and Synthetic Applications for Biochemical Use, Current Topics in Medicinal Chemistry, vol. 5, 1431-1457, 2005
2005 Shie, J. J., Fang, J. M., Kuo, C. J., Kuo, T. H., Liang, P. H., Huang, H. J., Yang, W. B., Lin, C. H., Chen, J. L., Wu, Y. T., Wong, C. H., Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease., J Med Chem, vol. 48(13), 4469-4473, 2005
2005 J. J. Shie, J. M. Fang, C. J. Kuo, T. H. Kuo, P. H. Liang, H. J. Huang, W. B. Yang, C. H. Lin, J. L. Chen, Y. T. Wu, C. H. Wong, Discovery of Potent Anilide Inhibitors Against the Severe Acute Respiratory Syndrome 3CL Protease, J. Med. Chem, vol. 48, 4469-4473, 2005
2005 S. C. Sue, (C. F. Chang, Y. T. Huang, C. Y. Chou, T. H. Huang, Challenges in NMR-based structural genomics, Physica A, vol. 350, 12-27, 2005
2005 Kouza, M., (Chang, C. F., Hayryan, S., Yu, T. H., Li, M. S., Huang, T. H., Hu, C. K., Folding of the Protein Domain hbSBD., Biophys J, vol. 89(5), 3353-3361, 2005
2005 Chang, C. K., Sue, S. C., Yu, T. H., Hsieh, C. M., Tsai, C. K., Chiang, Y. C., Lee, S. J., Hsiao, H. H., Wu, W. J., (Chang, C. F., Huang, T. H., The dimer interface of the SARS coronavirus nucleocapsid protein adapts a porcine respiratory and reproductive syndrome virus-like structure., FEBS Lett, vol. 579(25), 5663-5668, 2005
2005 Mahajan, A., Yuan, C., Pike, B. L., Heierhorst, J., (Chang, C. F., Tsai, M. D., FHA domain-ligand interactions: importance of integrating chemical and biological approaches., J Am Chem Soc, vol. 127(42), 14572-14573, 2005
2005 O. P. Charkin, N. M. Klimenko, T. P. Nguyen, D. O. Charkin, Y.-S. Wang, S.-C. Wei, H.-C. Chang, S. H. Lin, Theoretical study of fragmentation of heme and its ion with successive removal of carboxymethyl groups, Russian Journal of Inorganic Chemistry, vol. 50 (9), 1398-1407, 2005
2005 R.Y.L. Wang, (C. N. Shen, M. H. Lin, D. Tosh, C. H. Shih, Hepatocyte-like cells transdifferentiated from a pancreatic origin can support replication of hepatitis B virus, Journal of virology, vol. 79, 13116-13128, 2005