Selected Publications

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Year Paper Title
2006 K.I Lin*, Y.Y. Kao, H.K. Kuo, W.B. Yang, A Chou, H.H. Lin, A.L. Yu, C.H.Wong, Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor blimp-1, J. Biol. Chem, vol. 281, 24111-24123, 2006
2006 F. Huang, S. F. Haydock, D. Spiteller, T. Mironenko, T. L. Li, P. F. Leadlay, D. O'Hagan, J. B. Spencer*, The gene cluster for fluorometabolite biosynthesis in Streptomyces cattleya: a thioesterase confers resistance to fluoroacetyl-coenzyme A., CELL CHEMICAL BIOLOGY (CHEMISTRY & BIOLOGY), vol. 13(5), 475-484, 2006
2006 J. Y. Ho, Y. T. Huang, C. J. Wu, Y. S. Li, M. D. Tsai, T. L. Li*, Glycopeptide Biosynthesis: Dbv21/Orf2* from dbv/tcp Gene Clusters Are N-Ac-Glm Teicoplanin Pseudoaglycone Deacetylases and Orf15 from cep Gene Cluster Is a Glc-1-P Thymidyltransferase, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 128(42), 13694-13695, 2006
2006 C. J. Wu*, T. L. Li, H. W. Huang, Y. L. Chan, M. H. Tao, Development of an effective Japanese encephalitis virus-specific DNA vaccine, MICROBES AND INFECTION, vol. 8, 2578-2586, 2006
2006 Chiou SH, Yang YP, Lin JC, Hsu CH, Jhang HC, Yang YT, Lee CH, Ho LL, Hsu WM, Ku HH, Chen SJ, Chen SS, Chang MD, Wu CW*, (Juan LJ)*, The immediate early 2 protein of human cytomegalovirus (HCMV) mediates the apoptotic control in HCMV retinitis through up-regulation of the cellular FLICE-inhibitory protein expression., Journal of immunology (Baltimore, Md. : 1950), vol. 177(9), 6199-206, 2006
2006 F. C. Chen, T. J. Chuang*, The effects of multiple features of alternatively spliced exons on the Ka/Ks ratio test, BMC Bioinformatics, vol. 7, 259, 2006
2006 F. C. Chen, C. J. Chen, J. Y. Ho, T. J. Chuang*, Identification and evolutionary analysis of novel exons and alternative splicing events using cross-species EST-to-genome comparisons in human, mouse and rat, BMC Bioinformatics, vol. 7, 136, 2006
2006 F. C. Chen, S. S. Wang, C. J. Chen, W. H. Li, T. J. Chuang*, Alternatively and Constitutively Spliced Exons Are Subject to Different Evolutionary Forces, Mol Biol Evol, vol. 23, 675-682 (impact factor: 10.353; ranking: 14/290: BIOCHEMISTRY & MOLECULAR BIOLOGY), 2006
2006 L. C. Hwang, C. H. Bai, C. J. Chen, Prevalence of obesity and metabolic syndrome in Taiwan, J Formos Med Assoc, vol. 105, 626-635, 2006
2006 Y. C. Chien, C. F. Jan, H. S. Kuo, C. J. Chen, Nationwide hepatitis B vaccination program in Taiwan: Effectiveness in 20 years after it was launched, Epidemiol Rev, vol. 28, 126-135, 2006
2005 Jun Li, Ying-Chih Chang*, Preparation of End-Grafted Polymer Brushes by Nitroxide-Mediated Free Radical Polymerization of Vaporized Vinyl Monomers, LANGMUIR, vol. 21, 9562-9567, 2005
2005 L. R. Chen, Y. C. Wang, Y. W. Lin, S. Y. Chou, S. F. Chen, L. T. Liu, C. J. Kuo, T. S. Chen, S. H. Juang, Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors, Bioorg Med Chem Lett, vol. 15, 3058-3062, 2005
2005 J. J. Shie, J. M. Fang, T.H. Kuo, C. J. Kuo, P. H. Liang, H. J. Huang, J.T. Jan, Y. S. Cheng, C. H. Wong, Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 13, 5240-5252, 2005
2005 Shie, J. J., Fang, J. M., Kuo, C. J., Kuo, T. H., Liang, P. H., Huang, H. J., Yang, W. B., Lin, C. H., Chen, J. L., Wu, Y. T., Wong, C. H., Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease., J Med Chem, vol. 48(13), 4469-4473, 2005
2005 Chun-Ping Lu, Yi-Ning Lai, S.-H. Wu, Wei-Man Wang, Jean-Yin Chen, Lee-Chiang Lo, Design of a Mechanism-Based Probe for Neuraminidase to Capture Influenza Viruses, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 44, 6888-6892, 2005
2005 An-Tai Wu, Yi-Ping Yu, Wei Zou, S.-H. Wu, 9-O-Sulfation on α-NeuAc-(2-8)-NeuAc and inter-residue lactonization, CARBOHYDRATE RESEARCH, vol. 340, 1219-1223, 2005
2005 Chen AY, Shih SJ, Garriques LN, Rothenberg ML, (Hsiao M, Curran DP, Silatecan DB-67 is a novel DNA topoisomerase I-targeted radiation sensitizer, Mol Cancer Ther, vol. 4, 317-324. Cite 10, 2005
2005 C. Y. Wu, A. Brik, S. K. Wang, Y. H. Chen, C. H. Wong, Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ, Chembiochem, vol. 6, 2176-2180, 2005
2005 Brik, A., Wu, C. Y., Best, M. D., Wong, C. H., Tetrabutylammonium fluoride-assisted rapid N(9)-alkylation on purine ring: Application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ., Bioorganic & medicinal chemistry, vol. 13(15), 4622-4626, 2005
2005 G. T. Fan, Y. S. Pan. K. C. Lu, Y. P. Cheng, W. C. Lin, S. Lin, S. H. Lin, C. H. Wong, J. M. Fang, C. C. Lin Wong, C. H., Fang, J. M., C. C. Lin, Synthesis of alpha-galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes., Tetrahedron, vol. 61, 1855-1862, 2005
2005 G. T. Fan, Y. S. Pan. K. C. Lu, Y. P. Cheng, W. C. Lin, S. Lin, S. H. Lin, C. H. Wong, J. M. Fang, C. C. Lin, Synthesis of ?galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes, Tetrahedron, vol. 61, 1855-1862, 2005
2005 G. W. Xing, D. Wu, M. A. Poles, A. Horowitz, M. Tsuji, D. D. Ho, C. H. Wong, Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides, Bioorganic & medicinal chemistry, vol. 13, 2907-2916, 2005
2005 Zajonc DM, Maricic I, Wu D, Halder R, Roy K, Wong CH, Kumar V, Wilson IA, Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity., The Journal of experimental medicine, vol. 202(11), 1517-26, 2005
2005 S. H. Wei, H. Rosen, M. P. Matheu, M. G. Sanna, S. K. Wang, E. Jo, C. H. Wong, I. Parker, M. D. Cahalan, Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses, Nat Immunol, vol. 6, 1228-1235, 2005
2005 Y. Kinjo, D. Wu, G. Kim, G. W. Xing, M. A. Poles, D. D. Ho, M. Tsuji, K. Kawahara, C. H. Wong, M. Kronenberg, Recognition of bacterial glycosphingolipids by natural killer T cells, Nature, vol. 434, 520-525, 2005
2005 Sinchaikul, S., Pan, F. M., Cheng, C. W., Wong, C. H., Fang, J. M., Tseng, M. J., Chen, S. T., Protein microarray using alpha-amino acids as metal tags on chips., Bioorg Med Chem Lett, vol. 15(5), 1413-1416, 2005
2005 C. H. Wong, Protein glycosylation: new challenges and opportunities, J Org Chem, vol. 70, 4219-4225, 2005
2005 J. J. Shie, J. M. Fang, T. H. Kuo, C. J. Kuo, P. H. Liang, H. J. Huang, Y. T. Wu, J. T. Jan, Y. S.E. Cheng, C. H. Wong, Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters., Bioorganic & medicinal chemistry, vol. 13, 5240–5252, 2005
2005 M. M. Numa, L. V. Lee, C. C. Hsu, K. E. Bower, C. H. Wong, Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ, Chembiochem, vol. 6, 1002-1006, 2005
2005 Sawkar AR, Adamski-Werner SL, Cheng WC, Wong CH, Beutler E, Zimmer KP, Kelly JW, Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles., Chemistry & biology, vol. 12(11), 1235-44, 2005