Selected Publications

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Year Paper Title
2008 R. Payne, S. Ficht, W. A. Greenberg, C.-H. Wong, Cysteine-Free Peptide and Glycopeptide Ligations by Direct Aminolysis, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 47(23), 4411-4415, 2008
2008 S.-T. Chen, Y.-L. Lin, M.-T. Huang, M.-F. Wu, S.-C. Cheng, H.-Y. Lei, C.-K. Lee, T.-W. Chiou, C.-H. Wong, S.-L. Hsieh, CLEC5A is Critical for Dengue Virus-Induced Lethal Disease, Nature, vol. 453, 672-676, 2008
2008 T. R. Northen, J.-C. Lee, L. Hoang, J. Raymond, D.-R. Hwang, S.M. Yannone, C.-H. Wong, G. Siuzdak, A Nanostructure-Initiator Mass Spectrometry Based Enzyme Activity Assay, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105(10), 3678-3683, 2008
2008 R. D. Astronomo, H. K. Lee, C. N. Scanlan, R. Pantophlet, C. Y. Huang, I. A. Wilson, O. Blixt, R. A. Dwek, C.-H. Wong, D. R. Burton, A glycoconjugate antigen based on the recognition motif of a broadly-neutralising human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120, JOURNAL OF VIROLOGY, vol. 82, 6359-6368, 2008
2008 Giffin MJ, Heaslet H, Brik A, Lin YC, Cauvi G, Wong CH, McRee DE, Elder JH, Stout CD, Torbett BE, A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant., Journal of medicinal chemistry, vol. 51(20), 6263-6270, 2008
2008 M. J. Giffin, H. Heaslet, A. Brik, Y.-C. Lin, G. Cauvi, C.-H.Wong, D. E. McRee, J. H. Elder, C. D. Stout, B. E. Torbett, A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant, J. Med. Chem, vol. 51(20), 6263-6270, 2008
2008 M. W. Chen, T.-J. Cheng, Y. Huang, J.-T. Jan, S.H. Ma, A. Yu, C.-H. Wong, D. Ho, A Consensus-Hemagglutinin-Based DNA Vaccine that Protects Mice Against Divergent H5N1 Influenza Viruses, Proceedings of the national academy of sciences of the united states of america, vol. 105(36), 13538-13543, 2008
2008 J.-J. Shie, J.-M. Fang, C.-H. Wong, A Concise and Flexible Synthesis of the Potent Anti-Influenza Agents – Tamiflu and Tamiphosphor, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 47(31), 5788-5791, 2008
2008 Y. W. Lin, M. Y. Min, C. C. Lin, W. N. Chen, W. L. Wu, H. M. Yu, C. C. Chen, Identification and characterization if a subset of mouse sensory neurons that express acid-sensing ion channel 3, NEUROSCIENCE, vol. 151(2), 544-557, 2008
2008 H.J. Hsu, K.C. Tsai, Y.K. Sun, H.J. Chang, Y.J. Huang, H.M. Yu, C.H. Lin, S.S. Mao, A.S. Yang, Factor-Xa Active Site Substrate Specificity with Substrate Phage Display and Computational Molecular Modeling, accepted., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 283, 12343-12353., 2008
2008 C. Lin, P. T. Lai, K. S. Liao, W. T. Hung, W. B. Yang, J. M. Fang, Using molecular iodine in direct oxidative condensation of aldoses with diamines: An improved synthesis of aldo-benzimidazoles and aldo-naphthimidazoles for carbohydrate analysis, J. Org. Chem, vol. 73, 3848-3853, 2008
2008 W. T. Hung.; S. H. Wang.; C. H. Chen.; W. B. Yang, Structure determination of beta-glucans from Ganoderma lucidum with matrix-assisted laser desorption/ionization (MALDI) mass spectrometry, Molecules, vol. 13, 1538-1550, 2008
2008 Y. S. Hsieh, C. Chien, S. K. Liao, S. F. Liao, W. T. Hung, W. B. Yang, C. C. Lin, T. J. Cheng, C. C. Chang, J. M. Fang, C. H. Wong, Structure and bioactivity of the polysaccharides in medicinal plant Dendrobium huoshanense, Bioorganic & Medicinal Chemistry, vol. 16, 6054-6068, 2008
2008 M. L. Chen, A. K. Adak, N. C. Yeh, W. B. Yang, Y. J. Chuang, C. H. Wong, K. C. Hwang, J. R. Hwu, S. L. Hsieh, C. C. Lin, Fabrication of an oriented Fc-fused lectin microarray through boronate formation, Angewandte Chemie-International Edition, vol. 47, 8627-8630, 2008
2008 Shao, Y. M.; Yang, W. B.; Kuo, T. H.; Tsai, K. C.; Lin, C. H.; Yang, A. S.; Liang, P. H.; Wong, C. H., Design, Synthesis, and Evaluation of Trifluoromethyl Ketones as Inhibitors of SARS-CoV 3CL Protease, Bioorganic & Medicinal Chemistry, vol. 16, 4652-4660, 2008
2008 Wang SK, Liang PH, Astronomo RD, Hsu TL, Hsieh SL, Burton DR, Wong CH, Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN., Proceedings of the National Academy of Sciences of the United States of America, vol. 105(10), 3690-3695, 2008
2008 Tsai CM, Chiu YK, Hsu TL, Lin IY, Hsieh SL, Lin KI, Galectin-1 promotes immunoglobulin production during plasma cell differentiation., Journal of immunology, vol. 181(7), 4570-4579, 2008
2008 Tsou EL, Chen SY, Yang MH, Wang SC, Cheng TR, Cheng WC, Synthesis and biological evaluation of a 2-aryl polyhydroxylated pyrrolidine alkaloid-based library., Bioorganic & medicinal chemistry, vol. 16(24), 10198-10204, 2008
2008 Hsieh YS, Chien C, Liao SK, Liao SF, Hung WT, Yang WB, Lin CC, Cheng TJ, Chang CC, Fang JM, Wong CH, Structure and bioactivity of the polysaccharides in medicinal plant Dendrobium huoshanense., Bioorganic & medicinal chemistry, vol. 16(11), 6054-6068, 2008
2008 Cheng TJ, Sung MT, Liao HY, Chang YF, Chen CW, Huang CY, Chou LY, Wu YD, Chen YH, Cheng YS, Wong CH, Ma C, Cheng WC, Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics., Proceedings of the National Academy of Sciences of the United States of America, vol. 105(2), 431-436, 2008
2008 Chen MW, Cheng TJ, Huang Y, Jan JT, Ma SH, Yu AL, Wong CH, Ho DD, A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses., Proceedings of the National Academy of Sciences of the United States of America, vol. 105(36), 13538-13543, 2008
2008 Naik MT, (Chang CF, Kuo IC, Kung CC, Yi FC, Chua KY, Huang TH, Roles of structure and structural dynamics in the antibody recognition of the allergen proteins: an NMR study on Blomia tropicalis major allergen., Structure (London, England : 1993), vol. 16(1), 125-36, 2008
2008 C. F. Chang)*, Introduction to methods for fast multidimensional NMR, Chemistry, vol. 66(3), 199, 2008
2008 Wu HC, Wang Q, (Yang HI, Ahsan H, Tsai WY, Wang LY, Chen SY, Chen CJ, Santella RM, Urinary 15-F2t-isoprostane, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in Taiwan., CARCINOGENESIS, vol. 29(5), 971-976, 2008
2008 Chen CL, (Yang HI, Yang WS, Liu CJ, Chen PJ, You SL, Wang LY, Sun CA, Lu SN, Chen DS, Chen CJ, Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan., GASTROENTEROLOGY, vol. 135(1), 111-121, 2008
2008 Yang HI, Yeh SH, Chen PJ, Iloeje UH, Jen CL, Su J, Wang LY, Lu SN, You SL, Chen DS, Liaw YF, Chen CJ, Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma., JNCI-Journal of the National Cancer Institute, vol. 100(16), 1134-1143, 2008
2008 Jessome, L.; Hsu, N.-Y.; Wang, Y.-S.; Chen, C.-H., *, Matrix-assisted laser desorption/ionization mechanism study with dihydroxybenzoic acid isomers as matrices, Rapid Communications in Mass Spectrometry, vol. 22(2), 130-134., 2008
2008 Tsai, S.-T.; Chen, C.-H.; Lee, Y. T.; Wang, Y.-S., *, Desorption dynamics of neutral molecules in matrix-assisted laser desorption/ionization., Molecular Physics, vol. 106 (1-2), 239-247, 2008
2008 Chang C.-K.;Wu, C.-C.;* Wang, Y.-S.; Chang, H.-C., Selective extraction and enrichment of multiphosphorylated peptides using polyarginine-coated diamond nanoparticles, Analytical Chemistry, vol. 80(10), 3791-3797, 2008
2008 I-S. Chen, S. P. Huang, N. H. Jang-Liaw, (C. N. Shen, J. H. Wu, Molecular evidence for genetic differentiation of the Opsariichthys bidens complex (Teleostei: Cyprinidae) in southern China around the South China Sea and the validity of Opsariichthys hainanensis, The Raffles Bulletin of Zoology, vol. Supplement No. 19, 215-223, 2008