Selected Publications

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Year Paper Title
2013 Zhu J, Zhou L, Wu G, Konig H, Lin X, Li G, Qiu XL, Chen CF, Hu CM, Goldblatt E, Bhatia R, Chamberlin AR, Chen PL, Lee WH., A novel small molecule RAD51 inactivator overcomes imatinib-resistance in chronic myeloid leukaemia., EMBO Molecular Medicine, vol. 5, 353-365, 2013
2013 Ngo B, Hu CM, Guo XE, Ngo B, Wei R, Zhu J, Lee WH., Complementary interhelical interactions between three buried Glu-Lys pairs within three heptad repeats are essential for Hec1-Nuf2 heterodimerization and mitotic progression., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 288, 34403-34413, 2013
2013 Zulueta, M. M. L.; Lin, S.-Y.; Hu, Y.-P.; Hung, S.-C., Synthetic Heparin and Heparan Sulfate Oligosaccharides and their Protein Interactions, Current Opinion in Chemical Biology, vol. 17(6), 1023-1029, 2013
2013 Woolfson, D. N.; Hung, S.-C., Synthetic Biomolecules, Current Opinion in Chemical Biology, vol. 17(6), 925-928, 2013
2013 Zulueta, M. M. L.; Zhong, Y.-Q.; Hung, S.-C., Synthesis of Rare L-Hexoses and Their Related Biomolecules, Chemical Communications, vol. 49(32), 3275-3287, 2013
2013 Lu, F.-C.; Lico, L. S.; Hung, S.-C., Synthesis of Fluorogenic Substrate for α-L-Iduronidase, ARKIVOC, vol. 2013(2), 13-21, 2013
2013 Patil, P. S.; Lee, C.-C.; Huang, Y.-W.; Zulueta, M. M. L.; Hung, S.-C., Regioselective and Stereoselective Benzylidene Installation and One-pot Protection of D-mannose, Organic & Biomolecular Chemistry, vol. 11(16), 2605-2612, 2013
2013 Zulueta, M. M. L.; Lin, S.-Y.; Hung, S.-C., Chemical Synthesis of Oligosaccharides Based on Heparin and Heparan Sulfate, Trends in Glycoscience and Glycotechnology, vol. 25, 141-158, 2013
2013 Yi-Ching Chen, Jen-Hao Cheng, Zing Tsung-Yeh Tsai, Huai-Kuang Tsai*, (Trees-Juen Chuang)*, The Impact of Trans-Regulation on the Evolutionary Rates of Metazoan Proteins, NUCLEIC ACIDS RESEARCH, vol. 41(13), 6371-6380 (impact factor: 8.278; ranking: 27/290: BIOCHEMISTRY & MOLECULAR BIOLOGY), 2013
2013 Trees-Juen Chuang, Shian-Zu Wu, Yao-Ting Huang*, A Novel Framework for the Identification and Analysis of Duplicons between Human and Chimpanzee, BioMed Research International, vol. 264532, 2013
2013 Pan YW, Guo CW, Tu HY, Tsai CW, Cheng WC, Solid-Phase Synthesis of Diverse Spiroisoxazolinodiketopiperazines., ACS combinatorial science, vol. 15(8), 425-434, 2013
2013 Chen KT, Kuan YC, Fu WC, Liang PH, Cheng TJ, Wong CH, Cheng WC, Rapid preparation of mycobacterium N-glycolyl Lipid I and Lipid II derivatives: a biocatalytic approach., Chemistry-a European Journal, vol. 19(3), 834-838, 2013
2013 Cheng WC, Weng CY, Yun WY, Chang SY, Lin YC, Tsai FJ, Huang FY, Chen YR, Rapid modifications of N-substitution in iminosugars: development of new beta-glucocerebrosidase inhibitors and pharmacological chaperones for Gaucher disease., Bioorganic & medicinal chemistry, vol. 21(17), 5021-5028, 2013
2013 Huang SH, Wu WS, Huang LY, Huang WF, Fu WC, Chen PT, Fang JM, Cheng WC, Cheng TJ, Wong CH, New continuous fluorometric assay for bacterial transglycosylase using Forster resonance energy transfer., Journal of the American Chemical Society, vol. 135(45), 17078-17089, 2013
2013 Cheng TJ, Chan TH, Tsou EL, Chang SY, Yun WY, Yang PJ, Wu YT, Cheng WC, From Natural Product-Inspired Pyrrolidine Scaffolds to the Development of New Human Golgi alpha-Mannosidase II Inhibitors., Chemistry-An Asian Journal, vol. 8(11), 2600-2604, 2013
2013 Winny Ariesandi, Chi-Fon Chang, Tseng-Erh Chen, Yun-Ru Chen*, Temperature-dependent structural changes of Parkinson's alpha-synuclein reveal the role of pre-existing oligomers in alpha-synuclein fibrillization, PLoS One, vol. 8(1), e53487, 2013
2013 Yi-Ting Wang, Pan-Hsien Kuo, Chien-Hao Chiang, Jhe-Ruei Liang, (Yun-Ru Chen, Shuying Wang, James C. K. Shen, Hanna S. Yuan*., The truncated C-terminal RRM domain of TDP-43 plays a key role in forming proteinaceous aggregates., J Biol. Chem., vol. 288(13), 9049-9057, 2013
2013 3. Wei-Chieh Cheng*, Chen-Yi Weng, Wen-Yi Yun, Shang-Yu Chang, Yu-Chun Lin, Fuu-Jen Tsai, Fu-Yung Huang, (Yun-Ru Chen)., Rapid modifications of N-substitution in iminosugars: Development of new β-glucocerebrosidase inhibitors and pharmacological chaperones for Gaucher disease. , BIOORGANIC & MEDICINAL CHEMISTRY, vol. 1, 5021-5028, 2013
2013 Rong-Jie Chen, Wei-Wei Chang, Yu-Chun Lin, Pei-Lin Pheng, (Yun-Ru Chen)*, Alzheimer’s Amyloid-β Oligomers Rescue Cellular Prion Protein Induced Tau Reduction via Fyn Pathways, ACS Chemical Neuroscience, vol. 4(9), 1287-1296, 2013
2013 Man Hoang Viet, Chun-Yu Chen, Chin-Kun Hu, (Yun-Ru Chen)*, Mai Suan Li*., Discovery of Dihydrochalcone as potential lead for Alzheimer's disease: in silico and in vitro study, PLoS One, vol. 8(11), e79151, 2013
2013 Wei Chen, Fang Lu, Chiao-Chi V Chen, Kuan-Chi Mo, Yann Hung, Zhi-Xuan Guo, Chia-Hui Lin, Ming-Huang Lin, Yu-Hsuan Lin, Chen Chang, Chung-Yuan Mou, Manganese-Enhanced Magnetic Resonance Imaging of Rat Brain Based on Slow Cerebral Delivery of Mn(II) with Silica-Encapsulated MnxFe1–xO Nanoparticles, NMR in Biomedicine, vol. 26, 1176-1185, 2013
2013 Lan-Hui Li, Muh-Yong Yen, Chao-Chi Ho, Ping Wu, Chien-Chun Wang, Pawan Kumar Maurya, Pai-Shan Chen, Wei Chen, Wan-Yu Hsieh, Huei-Wen Chen*, Non-Cytotoxic Nanomaterials Enhance Antimicrobial Activities of Cefmetazole against Multidrug-Resistant Neisseria gonorrhoeae, PloS ONE, vol. 8, e64794, 2013
2013 Ping Wu, Shin-Sheng Yuan, Chao-Chi Ho, Wan-Yu Hsieh, Qi-Sheng Hong, Sung-Liang Yu, Wei Chen, Hsuan-Yu Chen, Chin-Di Wang, Ker-Chau Li, Pan-Chyr Yang, Huei-Wen Chen*, Focal Amplification of HOXD-Harboring Chromosome Region Is Implicated in Multiple-Walled Carbon Nanotubes-Induced Carcinogenicity, Nano Letters, vol. 13, 4632-4641, 2013
2013 Wei Chen, Ping-Hsing Tsai, Yann Hung, Shih-Hwa Chiou*, Chung-Yuan Mou*, Nonviral Cell Labeling and Differentiation Agent for Induced Pluripotent Stem Cells Based on Mesoporous Silica Nanoparticles, ACS Nano, vol. 7, 8423-8440, 2013
2013 Hsu LI, Chen GS, Lee CH, Yang TY, Chen YH, Wang YH, Hsueh YM, Chiou HY, Wu MM, Chen CJ*, Use of arsenic-induced palmoplantar hyperkeratosis and skin cancers to predict risk of subsequent internal malignancy, Am J Epidemiol, vol. 177, 202-212, 2013
2013 Chung CJ, Huang YL, Huang YK, Wu Meei-Maan, Chen SY, Hsueh YM*, Chen CJ, Urinary arsenic profiles and the risks of cancer mortality: a population-based 20-year follow-up study in arseniasis-endemic areas in Taiwan, Environ Res, vol. 122, 25-30, 2013
2013 Chiang CJ, Yang YW, You SL, Lai MS, Chen CJ*, Thirty-year outcomes of the national hepatitis B immunization program in Taiwan, JAMA-J Am Med Assoc, vol. 310(9), 974-976, 2013
2013 LI Hsu; YH Wang; HY Chiou; MM Wu; TY Yang; YH Chen; CH Tseng; CJ Chen, The association of diabetes mellitus with subsequent internal cancers in the arsenic-exposed area of Taiwan, J Asian Earth Sci, vol. 73, 452-459, 2013
2013 Loomba R*, Liu J, Yang HI*, Lee MH, Lu SN, Wang LY, Iloeje UH, You SL, Brenner D, Chen CJ for the R.E.V.E.A.L.-HBV Study Group, Synergistic effects of family history of hepatocellular carcinoma and hepatitis B virus infection on risk for incident hepatocellular carcinoma, Clinical Gastroenterology and Hepatology, vol. 11(12), 1636-1645.e3, 2013
2013 Loomba R, Yang HI, Su J, Brenner D, Barrett-Connor E, Iloeje U, Chen CJ, Synergism between obesity and alcohol in increasing the risk of hepatocellular carcinoma: a prospective cohort study, Am J Epidemiol, vol. 177, 333-342, 2013