Selected Publications

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Year Paper Title
2014 Chen CK, Yang CY, Hua KT, Ho MC, Johansson G, Jeng YM, Chen CN, Chen MW, Lee WJ, Su JL, Lai TC, Chou CC, Ho BC, Chang CF, Lee PH, Chang KJ, (Hsiao M, Lin MT, Kuo ML, LECT2 suppress hepatocellular carcinoma progression by targeting c-Met receptor, Hepatology, vol. Mar;59(3):974-85. Cite 3, 2014
2014 Hsu TI, Hsu CH, Lee KH, Lin JT, Chen CS, Chang KC, Su CY, (Hsiao M)*, Lu PJ, MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo., Oncogenesis, vol. 3, e99. Cite 3, 2014
2014 Lu WH, Lu PJ, Wu YS, Ho WY, Cheng PW, lai CC, (Hsiao M, Hsieh KS, Tseng CJ, Different impacts of alpha and beta blockers on survival in a rat model of fatal enterovirus 71 encephalitis, Anesthesiology, vol. May;120(5), 1192-1204. Cite 3, 2014
2014 Cheng PW, Ho WY, Su YT, Lu PJ, Chen BZ, Cheng WH, Lu WH, Sun GC, Yeh TC, (Hsiao M, Tseng CJ, Resveratrol decreases fructose-induced oxidative stress, mediated by NADPH oxidase via an AMPK-dependent mechanism, Brit J Pharmacol, vol. 171(11), 2739-2750. Cite 15, 2014
2014 Li KC, Hua KT, Lin YS, Su CY, Ko JY, (Hsiao M, Kuo ML, Tan CT, Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma., Mol Cancer, vol. 13, 172. Cite 5, 2014
2014 Wei MF, Chen MW, Chen KC, Lou PJ, Lin SY, Hung SC, (Hsiao M, Yao CJ, Shieh MJ, Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells, Autophagy, vol. 10(7), 1179-1192. Cite 22, 2014
2014 Hua KT, Wang MY, Chen MW, Wei LH, Chen CK, Ko CH, Jeng YM, Sung PL, Jan YH, (Hsiao M, Kuo ML, Yen ML, The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis., Mol Cancer, vol. 13, 189. Cite 8, 2014
2014 Yang YF, Jan YH, Liu YP, Yang CJ, Su CY, Lin YF, Chang YC, Lai TC, Chiou J, Tsai HY, Lu J, Shen CN, Shew JY, Lu PJ, Huang MS, (Hsiao M)*, Squalene Synthase Induces TNFR1 Enrichment in Lipid Rafts to Promote Lung Cancer Metastasis., American Journal of Respiratory and Critical Care Medicine, vol. 190(6), 675-687. Cite 16, 2014
2014 Su CY, Chang YC, Chan YC, Lin TC, Huang MS, Yang CJ, (Hsiao M)*, MTAP is an independent prognosis marker and the concordant loss of MTAP and p16 expression predicts short survival in non-small cell lung cancer patients., EJSO, vol. 40(9), 1143-1150. Cite 3, 2014
2014 Lee KH, Lin FC, Hsu TI, Lin JT, Guo JT, Tsai CH, Lee YC, Lee YC, Chen CL, (Hsiao M, Lu PJ, MicroRNA-296-5p (miR-296-5p) functions as a tumor suppressor in prostate cancer by directly targeting Pin1, Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1843(9), 2055-2066. Cite 13, 2014
2014 Cheng PW, Kang BH, Lu PJ, Lin SS, Ho WY, Chen HH, Hong LZ, Wu YS, (Hsiao M, Tseng CJ, Involvement of two distinct signalling pathways in IGF-1-mediated central control of hypotensive effects in normotensive and hypertensive rats., Acta Physiol, vol. 212(1), 28-38, 2014
2014 Hong CC, Chen PS, Chiou J, Chiu CF, Yang CY, (Hsiao M, Chang YW, Yu YH, Hung MC, Hsu NW, Shiah SG, Hsu NY, Su JL, miR-326 maturation is crucial for VEGF-C driven cortactin expression and esophageal cancer progression., Cancer Res, vol. Nov 1;74(21):6280-90. Cite 4, 2014
2014 Shiah SG, Hsiao JR, Chang WM, Chen YW, Jin YT, Wong TY, Huang JS, Tsai ST, Hsu YM, Chou ST, Yen YC, Jiang SS, Shieh YS, Chang IS, (Hsiao M, Chang JY, Downregulated miR-329 and miR-410 promote the proliferation and invasion of oral squamous cell carcinoma by targeting Wnt-7b., Cancer Res, vol. 74(24), 7560-7572. Cite 6, 2014
2014 Chang YW, Chen MW, Chiu CF, Hong CC, Cheng CC, (Hsiao M)*, Chen CA, Wei LH, Su JL, Arsenic trioxide inhibits CXCR4-mediated metastasis by interfering miR-520h/PP2A/NF-kappaB signaling in cervical cancer, Ann Surg Oncol, vol. 21(Suppl 4), 687-695, 2014
2014 J.-R. Chen, Y.-H. Yu, Y.-C. Tseng, W.-L. Chiang, M.-F. Chiang, Y.-A. Ko, Y.-K. Chiu, S.-H. Ma, C.-Y. Wu, J.-T. Jan, K.-I. Lin, C. Ma, C.-H. Wong, Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections, Proceedings of the National Academy of Sciences of the United States of America, vol. 111 (7), 2476-2481, 2014
2014 J. Lin, Y.-J. Chang, W.-B. Yang, A. L. Yu, C.-H. Wong, The Multifaceted Effects of Polysaccharides Isolated from Dendrobium huoshanense on Immune Functions with the Induction of Interleukin-1 Receptor Antagonist (IL-1ra) in Monocytes., PloS one, vol. 9(4), e94040, 2014
2014 C.-L. Chen, T.-C. Lin, S.-Y. Wang, J.-J. Shie, K.-C. Tsai, Y.-S. E. Cheng, J.-T. Jan, C.-J. Lin, J.-M. Fang, C.-H. Wong, Tamiphosphor Monoesters as Effective Anti-influenza Agents, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 81, 106-118, 2014
2014 Y.-W. Lou, P.-Y. Wang, S.-C. Yeh, P.-K. Chuang, S.-T. Li, C.-Y. Wu, K.-H. Khoo, M. Hsiao, T.-L. Hsu, C.-H. Wong, Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers, Proceedings of the National Academy of Sciences of the United States of America, vol. 111 (7), 2482-2487, 2014
2014 C.-Y. Wang, C.-Y. Wu, T.-J. Hung, C.-H. Wong, C.-H. Chen, Sequence-constructive SELEX: A new strategy for screening DNA aptamer binding to Globo H., Biochemical and biophysical research communications, vol. 452(3), 484-489, 2014
2014 P.-C. Chen, P.-K. Chuang, C.-H. Chen, J.-R. Chen, S.-W. Lin, C. Ma, T.-L. Hsu, C.-H. Wong, Role of N-linked glycans in the interactions of recombinant HCV envelope glycoproteins with cellular receptors., ACS chemical biology, vol. 9(7), 1437-1443, 2014
2014 J.-T. Hung, Y.-C. Tsai, W.-D. Lin, J.-T. Jan, K.-H. Lin, J.-R. Huang, J.-Y. Cheng, M.-W. Chen, C.-H. Wong, A. L. Yu, Potent adjuvant effects of novel NKT stimulatory glycolipids on hemagglutinin based DNA vaccine for H5N1 influenza virus., Antiviral research, vol. 107, 110-118, 2014
2014 B.-T. Hong, C.-L. Chen, Jim-Min Fang, Shi-Yun Wang, Wen-I Huang, Yih-Shyun E. Cheng, Chi-Huey Wong, Oseltamivir Hydroxamate and Acyl Sulfonamide Derivatives as Influenza Neuraminidase Inhibitors, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22(23), 6647-6654, 2014
2014 C.-S. Chu, P.-W. Lo, Y.-H. Yeh, P.-H. Hsu, S.-H. Peng, Y.-C. Teng, M.-L. Kang, C.-H. Wong, L.-J. Juan, O-GlcNAcylation regulates EZH2 protein stability and function., Proceedings of the National Academy of Sciences of the United States of America, vol. 111(4), 1355-1360, 2014
2014 H.-Y. Lee, C.-Y. Chen, T.-I. Tsai, S.-T. Li, K.-H. Lin, Y.-Y. Cheng, C.-T. Ren, T.-J. Cheng, C.-Y. Wu, C.-H. Wong, Immunogenicity study of Globo H derivatives with modification at the reducing or non-reducing end of the tumor antigen, J. Am. Chem. Soc., vol. 136(48), 16844-16853, 2014
2014 C.-H. Hsu, M. Schelwies, S. Enck, L.-Y. Huang, S.-H. Huang, Y.-F. Chang, T.-J. Cheng, W.-C. Cheng, C.-H. Wong, Iminosugar C-Glycoside Analogues of alpha-d-GlcNAc-1-Phosphate: Synthesis and Bacterial Transglycosylase Inhibition., The Journal of organic chemistry, vol. 79(18), 8629-8637, 2014
2014 S.-C. Lin, W.-C. Liu, J.-T. Jan, C.-H. Wong, S.-C. Wu, Glycan Masking of Hemagglutinin for Adenovirus Vector and Recombinant Protein Immunizations Elicits Broadly Neutralizing Antibodies against H5N1 Avian Influenza Viruses, PLoS One, vol. 9(3), e92822, 2014
2014 L.-Y. Huang, S.-H. Huang, Y.-C. Chang, W.-C. Cheng, T.-J. R. Cheng, C.-H. Wong, Enzymatic Synthesis of Lipid II and Analogues., Angewandte Chemie-International Edition, vol. 53(31), 8060-8065, 2014
2014 Y.-Y. Tseng, J.-M. Liou, T.-L. Hsu, W.-C. Cheng, M.-S. Wu, C.-H. Wong, Development of bacterial transglycosylase inhibitors as new antibiotics: Moenomycin A treatment for drug-resistant Helicobacter pylori., Bioorganic & medicinal chemistry letters, vol. 24(11), 2412-2414, 2014
2014 J.-M. Fang, Y.-S. Chen, H.-M. Yu, J.-J. Shie, T.-J. R. Cheng, C.-Y. Wu, C.-H. Wong, Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity., Bioorganic & medicinal chemistry, vol. 22(5), 1766-1772, 2014
2014 A.-K. Sauer, C.-H. Liang, J. Stech, B. Peeters, P. Quéré, C. Schwegmann-Wessels, C.-Y. Wu, C.-H. Wong, G. Herrler, Characterization of the sialic Acid binding activity of influenza a viruses using soluble variants of the h7 and h9 hemagglutinins., PloS one, vol. 9(2), e89529, 2014