Selected Publications

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Year Paper Title
2016 Kosheleva OK, Lai TC, Chen NG, (Hsiao M)*, Chen CH*, Selective killing of cancer cells by nanoparticle-assisted ultrasound., Journal of Nanobiotechnology, vol. June 14;14(1):46, 2016
2016 Chan YC, Chen CW, Chan MH, Chang YC, Chang MW, Chi LH, Yu HM, Lin YF, Tsai DP, Liu RS, (Hsiao M)*, MMP2-sensing up-conversion nanoparticle for fluorescence biosensing in head and neck cancer cells, Biosensors & Bioelectronics, vol. Jun 15;80:131-139, Cite 17, 2016
2016 Lin CH, Tsai CH, Yeh CT, Liang JL, Hung WC, Lin FC, Chang WL, Li HY, Yao YC, Hsu TI, Lee YC, Wang YC, Sheu BS, Lai WW, Calkins MJ, (Hsiao M)*, Lu PJ, MiR-193a-5p/ERBB2 act as concurrent chemoradiation therapy response indicator of esophageal squamous cell carcinoma., Oncotarget, vol. June 28;7(26):39680-39693, 2016
2016 Peng HY, Jiang SS, Hsiao JR, (Hsiao M, Hsu YM, Wu GH, Chang WM, Chang JY, Jin SC, Shiah SG, IL-8 induces miR-424-5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinoma, Mol Oncol, vol. Jun;10(6), 895-909, 2016
2016 Yang YC, Cheng TY, Huang SM, Su CY, Yang PW, Lee JM, Chen CK, (Hsiao M, Hua KT, Kuo ML, Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR association., Oncogene, vol. Jun 30;35(26), 3387-98, 2016
2016 Lin CW, Yang WE, Lee WJ, Hua KT, Hsieh FK, (Hsiao M, Chen CC, Chow JM, Chen MK, Yang SF, Chien MH, Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with favourable prognosis., Carcinogenesis, vol. Jul;37(7), 712-722, 2016
2016 Su CY, Chang YC, Yang CJ, Huang MS, (Hsiao M)*, The opposite prognostic effect of NDUFS1 and NDUFS8 forms a prognostic panel for non-small cell lung cancer by reflecting the oncojanus role of mitochondrial complex I, Scientific Reports, vol. Aug 12;6, 31357, 2016
2016 Chen CK, Yu WH, Cheng TY, Chen MW, Su CY, Yang YC, Kuo TC, Lin MT, (Hsiao M, Hua KT, Hung MC, Kuo ML, Inhibition of VEGF165/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis, Scientific Reports, vol. Aug 10;6, 31398, 2016
2016 Lai CC, Cheng PW, Yeh TC, Lu PJ, (Hsiao M, Liu CP, Tseng CJ, Paricalcitol attenuates cardiac fibrosis and expression of endothelial cell transition markers in isoproterenol-induced cardiomyopathic rats, Critical Care Medicine, vol. 44(9), e866-e874, 2016
2016 Wei L, Su YK, Lin CM, Chao TY, Huynh TT, Jan HJ, Whang-Peng J, Chiou JF, Wu AT, (Hsiao M)*, Preclinical investigation of Ibrutinib, a Bruton’s kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes, Oncotarget, vol. Oct. 25;7(43), 69961-975, 2016
2016 Chan MH, Chen CW, Lee IJ, Chan YC, Tu DT, (Hsiao M)*, Chen CH, Chen XY, Liu RS, Near-infrared light-mediated photodynamic therapy nanoplatform by electrostatic assembly of NaYF4:Yb/Tm upconversion nanoparticles with graphitic carbon nitride quantum dots, Inorganic Chemistry, vol. 55(20), 10267-10277, 2016
2016 Chen CW, Chan YC, (Hsiao M)*, Liu RS, Plasmon-enhanced photodynamic cancer therapy by upconversion nanoparticles conjugated with Au nanorods, ACS Applied Materials & Interfaces, vol. 1, 1, 2016
2016 Lo YL, Liou GG, Lyu JH, (Hsiao M, Hsu TL, Wong CH*, Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex., PLoS One, vol. Nov 10;11(11), e0166474, 2016
2016 Chen HH, Cheng PW, Ho WY, Lu PJ, Lai CC, Tseng YM, Fang HC, Sun GC, (Hsiao M, Liu CP, Tseng CJ, Renal denervation improves the baroreflex and GABA system normalization in chronic kidney disease-associated hypertension, Scientific Reports, vol. 6, 38447, 2016
2016 Kuo TC, Chen CK, Hua KT, Yu P, Lee WJ, Chen MW, Jeng YM, Chien MH, Kuo KT, (Hsiao M, Kuo ML, Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells., Cancer Letters, vol. Dec 28;383(2), 282-294, 2016
2016 Chang WM, Lin YF, Su CY, Peng HY, Chang YC, Lai TC, Wu GH, Hsu YM, Chi LH, Hsiao JR, Chen CL, Chang JY, Shieh YS, (Hsiao M)*, Shiah SG, Dysregulation of Runx2/Activin A axis upon miR376c downregulation promotes lymph node metastasis in head and neck squamous cell carcinoma., Cancer Research, vol. 76(24),7140-7150, Cite 16, 2016
2016 L. Krasnova, C.-H. Wong, Understanding the Chemistry and Biology of Glycosylation with Glycan Synthesis, Annual Review of Biochemistry, vol. 85, 599-630, 2016
2016 G. B. E. Stewart-Jones, C. Soto, T. Lemmin, G.-Y. Chuang, A. Druz, R. Kong, P. V. Thomas, K. Wagh, T. Zhou, A.-J. Behrens, T. Bylund, C. W. Choi, J. R. Davison, I. S. Georgiev, M. G. Joyce, Y. D. Kwon, M. Pancera, J. Taft, Y. Yang, B. Zhang, S. S. Shivatare, V. S. Shivatare, C.-C. D. Lee, C.-Y. Wu, C. A. Bewley, D. R. Burton, W. C. Koff, M. Connors, M. Crispin, B. T. Korber, C.-H. Wong, J. R. Mascola, P. D. Kwong, Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G., Cell, vol. 165(4), 813-826, 2016
2016 C.-H. Hsu, S. Park, D. E. Mortenson, B. L. Foley, X. Wang, R. J. Woods, D. A. Case, E. T. Powers, C.-H. Wong, H. J. Dyson, J. W. Kelly, The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate., Journal of the American Chemical Society, vol. 138(24), 7636-7648, 2016
2016 S. K. C. Cheung, P.-K. Chuang, H.-W. Huang, W. W. Hwang-Verslues, C. H.-H. Cho, W.-B. Yang, C.-N. Shen, M. Hsiao, T.-L. Hsu, C.-F. Chang, C.-H. Wong, Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells., Proceedings of the National Academy of Sciences of the United States of America, vol. 113(4), 960-965, 2016
2016 T.-C. Kuo, L.-W. Li, S.-H. Pan, J.-M. Fang, J.-H. Liu, T.-R. Cheng, C.-J. Wang, P.-F. Hung, H.-Y. Chen, T.-M. Hong, Y.-L .Hsu, C.-H. Wong, P.-C. Yan, Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin., JOURNAL OF MEDICINAL CHEMISTRY, vol. 59(18), 8521-8534, 2016
2016 T.-N. Wu, K.-H. Lin, Y.-T. Wu, J.-R. Huang, J.-T. Hung, J.-C. Wu, C.-Y. Chen, K.-C. Chu, N.-H. Lin, A. L.Yu, C.-H. Wong, Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation., ACS chemical biology, vol. 11(12), 3431-3441, 2016
2016 P.-C. Wang, J.-M. Fang, K.-C. Tsai, S.-Y. Wang, W.-I. Huang, Y.-S. Cheng, R. C., C.-H. Wong, Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors., Journal of medicinal chemistry, vol. 59(11), 5297-5310, 2016
2016 S. S. Shivatare, S.-H. Chang, T.-I. Tsai, S. Y. Tseng, Y.-S. Lin, Y.-Y. Cheng, C.-T. Ren, S. Pawar, C.-S. Tsai, H.-W. Shi, Y.-F. Zeng, C.-H. Liang, P. D. Kwong, D. R. Burton, C.-Y. Wu, C.-H. Wong, Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies, Nature Chemistry, vol. 8 (4), 338-346, 2016
2016 Y. Kizuka, S. Funayama, H. Shogomori, M. Nakano, K. Nakajima, R. Oka, S. Kitazume, Y. Yamaguchi, M. Sano, H. Korekane, T.-L. Hsu, H.-Y. Lee, C.-H. Wong, N. Taniguchi, High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery., Cell Chemical Biology, vol. 23(7), 782-792, 2016
2016 S.-C. Yeh, P.-Y. Wang, Y.-W. Lou, K.-H. Khoo, M. Hsiao, T.-L. Hsu, C.-H. Wong, Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity., Proceedings of the National Academy of Sciences of the United States of America, vol. 113(20), 5592-5597, 2016
2016 L. Krasnova, C.-H. Wong, Exploring human glycosylation for better therapies., MOLECULAR ASPECTS OF MEDICINE, vol. S0098-2997, 2016
2016 D. T. MacLeod, N. M. Choi, B. Briney, F. Garces, L. S. Ver, E. Landais, B. Murrell, T. Wrin, W. Kilembe, C.-H. Liang, A. Ramos, C.-B. Bian, L. Wickramasinghe, L. Kong, K. Eren, C.-Y. Wu, C.-H. Wong, S. L. Kosakovsky Pond, I. A. Wilson, D. R. Burton, P. Poignard, Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch., Immunity, vol. 44(5), 1215-1226, 2016
2016 Y.-L. Lo, G.-G. Liou, C.-H. Lu, M. Hsiao, T.-L. Hsu, C.-H. Wong, Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex., PloS one, vol. 11(11), e0166474, 2016
2016 D. Sok, M. Pauthner, B. Briney, J.-H. Lee, K. L.Saye-Francisco, J. Hsueh, A. Ramos, K.-M. Le, M. Jones, J. G. Jardine, R. Bastidas, A. Sarkar, C.-H. Liang, S. S. Shivatare, C.-Y. Wu, W. R. Schief, C.-H. Wong, I. A. Wilson, A. B. Ward, J. Zhu, P. Poignard, D. R. Burton, A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans., Immunity, vol. 45(1), 31-45, 2016