Selected Publications

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Year Paper Title
2017 Chu YJ, (Yang HI, Wu HC, Liu J, Wang LY, Lu SN, Lee MH, Jen CL, You SL, Santella RM, Chen CJ, Aflatoxin B1 exposure increases the risk of cirrhosis and hepatocellular carcinoma in chronic hepatitis B virus carriers., International journal of cancer, vol. 141(4), 711-720, 2017
2017 Huang CF, Yeh ML, Huang CI, Lin YJ, Tsai PC, Lin ZY, Chan SY, Chen SC, Yang HI, Huang JF, Lu SN, Dai CY, Jen CL, Yuan Y, L'Italien G, Wang LY, Lee MH, Yu ML, Chuang WL, Chen CJ, Risk of hepatitis C virus related hepatocellular carcinoma between subjects with spontaneous and treatment-induced viral clearance., Oncotarget, vol. 8(27), 43925-43933, 2017
2017 Lai TS, Lee MH, (Yang HI, You SL, Lu SN, Wang LY, Yuan Y, L'Italien G, Chien KL, Chen CJ, Hepatitis C Viral Load, Genotype, and Increased Risk of Developing End-stage Renal Disease: REVEAL-HCV Study., HEPATOLOGY, vol. 66(3), 784-793, 2017
2017 H. Lee, Y.-H. Lai, Y.-M. Ou, C.-W. Tsao, Y.-J. Jheng, S.-Y. Kuo, H.-T. Chang, Y.-S. Wang*, Enhancing carbohydrate ion yield by controlling crystalline structures in matrix-assisted laser desorption/ionization mass spectrometry, ANALYTICA CHIMICA ACTA, vol. 994, 49-55, 2017
2017 Hsieh, C.C., I.M. Shyu, W.Y. Liao, T.H. Chen, S.E. Wang, P.C. Lu, P.Y. Lin, Y.B. Chen, W.Y. Mao, H.Y. Han, M. Hsiao, W.B. Yang, W.S. Li, Y.P. Sher, (C.N. Shen*, Elevation of beta-galactoside alpha 2,6-sialyltransferase 1 modulated in a fructose-responsive manner promotes pancreatic cancer metastasis, Oncotarget, vol. 8(5), 7691-7709, 2017
2017 Y.T. Lin, C.K. Wang, S.C. Yang, S.C. Hsu, H. Lin, F.P. Chang, T. C. Kuo, (C.N. Shen, M. Hsiao, P.M. Chiang, F. L. Lu, J. Lu, Elimination of undifferentiated human embryonic stem cells by cardiac glycosides, Scientific Reports, vol. 7(1), 5289, 2017
2017 C.L. Hsieh, C.M. Liu, H.A. Chen, S.T. Yang, K. Shigemura, K. Kitagawa, F. Yamamichi, M. Fujisawa, Y.R. Liu, W.H. Lee, K.C. Chen, (C.N. Shen, C.C. Lin, L. Chung, S.Y. Sung., Reactive oxygen species-mediated switching expression of MMP-3 in stromal fibroblasts and cancer cells during prostate cancer progression., Scientific Reports, vol. 7(1), 9065, 2017
2017 W.C. Yang, Y.S. Hwang, Y.Y. Chen, C.L. Liu, (C.N. Shen, W.H. Hong, S.M. Lo, C.R. Shen, Interleukin-4 supports the suppressive immune responses elicited by regulatory T cells, Frontiers in Immunology, vol. 8, 1508, 2017
2017 Chen CL, Hsu JC, Lin CW, Wang CH, Tsai MH, Wu CY, Wong CH*, (Ma C)*, Crystal Structure of a Homogeneous IgG-Fc Glycoform with the N-Glycan Designed to Maximize the Antibody Dependent Cellular Cytotoxicity., ACS chemical biology, vol. 12(5), 1335-1345, 2017
2017 Hsieh MH, Chen YT, Chen YT, Lee YH, (Lu J, Chien CL, Chen HF, Ho HN, Yu CJ, Wang ZQ, Teng SC, PARP1 controls KLF4-mediated telomerase expression in stem cells and cancer cells., Nucleic acids research, vol. 45(18), 10492-10503, 2017
2017 Kuan II, Liang KH, Wang YP, Kuo TW, Meir YJ, Wu SC, Yang SC, (Lu J)*, Wu HC*, EpEX/EpCAM and Oct4 or Klf4 alone are sufficient to generate induced pluripotent stem cells through STAT3 and HIF2alpha., Scientific reports, vol. 7, 41852, 2017
2017 Lin YT, Wang CK, Yang SC, Hsu SC, Lin H, Chang FP, Kuo TC, Shen CN, Chiang PM, Hsiao M, Lu FL, (Lu J)*, Elimination of undifferentiated human embryonic stem cells by cardiac glycosides., Scientific reports, vol. 7(1), 5289, 2017
2017 Lai PL, Lin H, Chen SF, Yang SC, Hung KH, Chang CF, Chang HY, Lu FL, Lee YH, Liu YC, Huang HC*, (Lu J)*, Efficient Generation of Chemically Induced Mesenchymal Stem Cells from Human Dermal Fibroblasts., Scientific reports, vol. 7, 44534, 2017
2017 Wang CK, Yang SC, Hsu SC, Chang FP, Lin YT, Chen SF, Cheng CL, Hsiao M, Lu FL, (Lu J)*, CHAC2 is essential for self-renewal and glutathione maintenance in human embryonic stem cells., Free radical biology & medicine, vol. 113, 439-451, 2017
2017 Lin Shan-Meng, (Lin Su-Chang, Hong Jhen-Yi, Su Tsung-Wei, Kuo Bai-Jiun, Chang Wei-Hsin, Tu Yi-Fan, Lo Yu-Chih*, Structural Insights into Linear Tri-ubiquitin Recognition by A20-Binding Inhibitor of NF-κB, ABIN-2, STRUCTURE, vol. 25(1), 66-78, 2017
2017 Tsung-Wei Su, Chao-Yu Yang, Wen-Pin Kao, Bai-Jiun Kuo, Shan-Meng Lin, Jung-Yaw Lin, Yu-Chih Lo*, (Su-Chang Lin)*, Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome, STRUCTURE, vol. 25(3), 407-420, 2017
2017 Lai, C.-Y., Su, Y.-W., (Lin, K.-I, Hsu, L.-C., Chuang, T.-H., Natural modulators of endosomal Toll-like receptor-mediated psoriatic skin inflammation, Journal of Immunology Research, vol. 10.1155/2017, 7807313, 2017
2017 Wu, J.-L., Chiang, M.-F., Hsu, P.-H., Tsai, D.-Y., Hung, K.-H., Wang, Y.-H., Angata, T.*, Lin, K.-I)*, O-GlcNAcylation is required for B cell homeostasis and antibody responses, NATURE COMMUNICATIONS, vol. 8(1):1854, 2017
2017 Y. W. Chen, C. H. Lee, Y. L. Wang, T. L. Li, H. C. Chang*, Nanodiamonds as nucleating agents for protein crystallization, LANGMUIR, vol. 33(26), 6521-6527, 2017
2017 Lee CC, Peng SH, Shen L, Lee CF, Du TH, Kang ML, Xu GL, Upadhyay AK, Cheng X, Yan YT, Zhang Y*, (Juan LJ)*, The Role of N-alpha-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting., Molecular Cell, vol. 68(1), 89-103.e7, 2017
2017 Huang S.-C., Wei P.-C., (Hwang-Verslues W.W., Kuo W.-H., Jeng Y.-M., Hu C.-H., Shew J.-Y., Huang C.-S., Chang K.-J., Lee E. Y.-H. P., Lee W.-H.*, TGF-β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB, EMBO MOLECULAR MEDICINE, vol. 9(12), 1660-1680, 2017
2017 Huang CK, Chang PH, Kuo WH, Chen CL, Jeng YM, Chang KJ, Shew JY, Hu CM, Lee WH., Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate., nature communications, vol. 8, 14706, 2017
2017 Huang SC, Wei PC, Hwang-Verslues WW, Kuo WH, Jeng YM, Hu CM, Shew JY, Huang CS, Chang KJ, Lee EY, Lee WH, TGF-β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB., EMBO molecular medicine, vol. 9, 1660-1680, 2017
2017 Padiyar, L. T.; Zulueta, M. M. L.; Sabbavarapu, N. M.; (Hung, S.-C.*, Yb(OTf)3-Catalyzed Desymmetrization of myo-Inositol-1,3,5-Orthoformate and Its Application in the Synthesis of Chiral Inositol Phosphates, J. Org. Chem, vol. 82, 11418-11430, 2017
2017 Tsai, C.-T.; Zulueta, M. M. L.; (Hung, S.-C.*, Synthetic Heparin and Heparan Sulfate: Probes in Defining Biological Functions, Curr. Opin. Chem. Biol., vol. 21, 152-159, 2017
2017 Huang, T.-Y.; Irene, D.; Ku, C.-C.; Zulueta, M. M. L.; Tai, T.-J.; Lain, S.-H.; Cheng, C.-P.; Tsai, P.-X.; Lin, S.-Y.; Chen, Z.-G.; Hsiao, C.-D.; Chyan, C.-L.*; (Hung, S.-C.*, Structure of the Complex between a Heparan Sulfate Octasaccharide and Mycobacterial Heparin-Binding Hemagglutinin, Angew. Chem. Int. Ed, vol. 56, 4192-4196, 2017
2017 Ho, K.-M.; Zulueta, M. M. L.; (Hung, S.-C.*, Stereoselective One-pot Synthesis of Polypropionates, Nat. Commun, vol. 8, 679, 2017
2017 Hughes, A. J.; Meneghetti, M. C. Z.; Huang, T.-Y.; (Hung, S.-C.); Elli, S.; Guerrini, M.; Rudd, T. R.; Lima, M. A.*; Yates, E. A.*, Investigating the Relationship between Temperature, Conformation and Calcium Binding in Heparin Model Oligosaccharides, Carbohydr. Res, vol. 438, 58-64, 2017
2017 Zheng RB, Jegouzo SAF, Joe M, Bai Y, Tran HA, Shen K, Saupe J, Xia L, Ahmed MF, Liu YH, Patil PS, Tripathi A, (Hung SC, Taylor ME, Lowary TL, Drickamer K, Insights into Interactions of Mycobacteria with the Host Innate Immune System from a Novel Array of Synthetic Mycobacterial Glycans., ACS chemical biology, vol. 12(12), 2990-3002, 2017
2017 Prados-Rosales, R.*; Carreño L.; Weinrick, B.; Lowary, T.; Baena, A.; Joe, M.; Bai, Y.; Kalscheuer, R.; Batista-Gonzalez, A.; Saavedra, N.; Chen, T.; Blanc, C.; (Hung, S.-C.); Tripathi, A.; Xu, J.; Glatman-Freedman, A.; Jacobs, W.; Chan, J.; Porcelli, S.; Achkar, J.; Casadevall, A., Enhanced Control of Mycobacterium tuberculosis Extrapulmonary Dissemination in Mice by an Arabinomannan-Protein Conjugate Vaccine, PLOS PATHOGENS, vol. 13, e1006250, 2017