Selected Publications

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Year Paper Title
2023 Trees-Juen Chuang*, Tai-Wei Chiang, Chia-Ying Chen, Assessing the impacts of various factors on circular RNA reliability, LIFE SCIENCE ALLIANCE, vol. 6(5), e202201793, 2023
2023 Marieke Vromman, Jasper Anckaert, Stefania Bortoluzzi, Alessia Buratin, Chia-Ying Chen, Qinjie Chu, (Trees-Juen Chuang, Roozbeh Dehghannasiri, Christoph Dieterich, Xin Dong, Paul Flicek, Enrico Gaffo, Wanjun Gu, Chunjiang He, Steve Hoffmann, Osagie Izuogu, Michael S. Jackson, Tobias Jakobi, Eric C. Lai, Justine Nuytens, Julia Salzman, Mauro Santibanez-Koref, Peter Stadler, Olivier Thas, Eveline Vanden Eynde, Kimberly Verniers, Guoxia Wen, Jakub Westholm, Li Yang, Chu-Yu Ye, Nurten Yigit, Guo-Hua Yuan, Jinyang Zhang, Fangqing Zhao, Jo Vandesompele, Pieter-Jan Volders, Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision., NATURE METHODS, vol. 20, 1159-1169 (impact factor: 48.0; Rank: 1/77), 2023
2023 Yu-Chen Chen, Chia-Ying Chen, Tai-Wei Chiang, Ming-Hsien Chan, Michael Hsiao, Huei-Mien Ke, Isheng Jason Tsai, Trees-Juen Chuang*, Detecting intragenic trans-splicing events from non-co-linearly spliced junctions by hybrid sequencing, NUCLEIC ACIDS RESEARCH, vol. 51(15), 7777-7797 (SCI impact factor: 16.6; Rank (BIOCHEMISTRY & MOLECULAR BIOLOGY): 6/313), 2023
2023 Li Huang-Yi, Lee Ni-Chung, Chiu Yu-Ting, Chang Yu-Wen, Lin Chu-Chung, Chou Cheng-Li, Chien Yin-Hsiu, Hwu Wuh-Liang, Cheng Wei-Chieh, Harnessing polyhydroxylated pyrrolidines as a stabilizer of acid alpha-glucosidase (GAA) to enhance the efficacy of enzyme replacement therapy in Pompe disease, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 78, 117129, 2023
2023 Lin Hung-Yi, Chang Shih-Ying, Teng Hsuan-Hsuan, Wu Hsi-Ju, Li Huang-Yi, Cheng Chia-Chun, Chuang Chih-Kuang, Lin Hsiang-Yu, Lin Shuan-Pei, Cheng Wei-Chieh, Discovery of small-molecule protein stabilizers toward exogenous alpha-l-iduronidase to reduce the accumulated heparan sulfate in mucopolysaccharidosis type I cells, European Journal of Medicinal Chemistry, vol. 247, 115005, 2023
2023 Tien-Wei Lin, Jung-Kai Chang, Yih-Ru Wu, Tsung-Hsien Sun, Yang-Yu Cheng, Chien-Tai Ren, Mei-Hung Pan, Jin-Lin Wu, Kuo-Hsuan Chang, Hwai-I Yang, Chiung-Mei Chen*, Chung-Yi Wu*, Yun-Ru Chen)*, Ganglioside-focused Glycan Array Reveals Abnormal Anti-GD1b Auto-antibody in Plasma of Preclinical Huntington’s Disease, MOLECULAR NEUROBIOLOGY, vol. 60(7), 3873-3882, 2023
2023 Tien-Ying Tsai§, Chun-Yu Chen§, Tien-Wei Lin, Tien-Chang Lin, Feng-Lan Chiu, Orion Shih, Ming-Yun Chang, Yu-Chun Lin, An-Chung Su, U-Ser Jeng, Hung-Chih Kuo, Chi-Fon Chang, Yun-Ru Chen)*, Amyloid Modifier SERF1a Interacts with PolyQ-expanded Huntingtin Exon 1 via Helical Interactions and Exacerbates PolyQ-induced Toxicity, Communications Biology, vol. 6, 767, 2023
2023 Yichu Nie(#, Wei Chen(#, Yong Kang(#, Xue Yuan, Yongjiang Li, Jun Zhou, Wei Tao*, Xiaoyuan Ji*, (#: Co-first author, equal contribution, Two-dimensional porous vermiculite-based nanocatalysts for synergetic catalytic therapy, Biomaterials, vol. 295, 122031, 2023
2023 Jiang Ouyang, Zhongyang Zhang, Bo Deng, Jinggong Liu, Liqiang Wang, Haijun Liu, Seyoung Koo, Shuying Chen, Yongjiang Li, Alexey V. Yaremenko, Xiangang Huang, Wei Chen, Yuhan Lee, Wei Tao*, Oral drug delivery platforms for biomedical applications, Materials Today, vol. 62, 296-326, 2023
2023 Liu Yu(#, Mian Yu(#, Wei Chen(#, Shengjie Sun, Wenxin Huang, Tianqi Wang, Zhangwen Peng, Zewen Luo, Yixuan Fang, Yongjiang Li, Yang Deng, * Meiying Wu, * Wei Tao*, (#: Co-first author, equal contribution, In situ separable nanovaccines with stealthy bioadhesive capability for durable cancer immunotherapy, Journal of the American Chemical Society, vol. 145, 8375-8388, 2023
2023 Jiang Ouyang, Bo Deng, Binhua Zou, Yongjiang Li, Qingyue Bu, Yuan Tian, Mingkai Chen, Wei Chen, Na Kong, Tianfeng Chen*, Wei Tao*, Oral hydrogel microbeads-mediated in situ synthesis of selenoproteins for regulating intestinal immunity and microbiota, Journal of the American Chemical Society, vol. 145, 12193-12205, 2023
2023 Wei Chen, Yongjiang Li, Chuang Liu, Yong Kang, Duotian Qin, Shuying Chen, Jun Zhou, Hai-Jun Liu, Bijan Emiliano Ferdows, Dylan Neal Patel, Xiangang Huang, Seyoung Koo, Na Kong, Xiaoyuan Ji, Yihai Cao, Wei Tao*, Tian Xie*, In situ Engineering of Tumor-Associated Macrophages via a Nanodrug-Delivering-Drug (β-Elemene@Stanene) Strategy for Enhanced Cancer Chemo-Immunotherapy., Angewandte Chemie International Edition, vol. 62, e202308413, 2023
2023 Hai-Jun Liu(#, Wei Chen(#, Gongwei Wu(#, Jun Zhou, Chuang Liu, Zhongmin Tang, Xiangang Huang, Jingjing Gao, Yufen Xiao, Na Kong, Nitin Joshi, Yihai Cao, Reza Abdi, Wei Tao* (#: Co-first author, equal contribution, Glutathione-scavenging nanoparticle-mediated PROTACs delivery for targeted protein degradation and amplified antitumor effects, Advanced Science, vol. 10, 2207439, 2023
2023 Siyue Ma(#, Ji Hyeon Kim(#, Wei Chen(#, Lu Li, Jieun Lee, Junlian Xue, Yuxia Liu, Guang Chen, * Bo Tang, * Wei Tao, * Jong Seung Kim* (#: Co-first author, equal contribution, Cancer Cell-Specific Fluorescent Prodrug Delivery Platforms, Advanced Science, vol. 10, 2207768, 2023
2023 Shuying Chen(#, Xiangang Huang(#, Yonger Xue(#, Ester Álvarez-Benedicto(#, Yesi Shi, Wei Chen, Seyoung Koo, Daniel J. Siegwart*, Yizhou Dong*, Wei Tao*, Nanotechnology-based mRNA vaccines, Nature Reviews Methods Primers, vol. 3, 63, 2023
2023 Qimanguli Saiding, Zhongyang Zhang, Shuying Chen, Fan Xiao, Yumeng Chen, Yongjiang Li, Xueyan Zhen, Muhammad Muzamil Khan, Wei Chen, Seyoung Koo*, Na Kong*, Wei Tao*, Nano-bio interactions in mRNA nanomedicine: Challenges and opportunities for targeted mRNA delivery, Advanced Drug Delivery Reviews, vol. 203, 115116, 2023
2023 Zhongmin Tang(#, Xinru You(#, Yufen Xiao(#, Wei Chen, Yongjiang Li, Xiangang Huang, Haijun Liu, Fan Xiao, Chuang Liu, Seyoung Koo, Na Kong, Wei Tao*, Inhaled mRNA nanoparticles dual-targeting cancer cells and macrophages in the lung for effective transfection, Proceedings of the National Academy of Sciences USA, vol. 120, e2304966120, 2023
2023 Yongjiang Li(#, Wei Chen(#, Yong Kang, Xueyan Zhen, Zhuoming Zhou, Chuang Liu, Shuying Chen, Xiangang Huang, Hai-Jun Liu, Seyoung Koo, Na Kong, Xiaoyuan Ji, Tian Xie*, Wei Tao* (#: Co-first author, equal contribution, Nanosensitizer-mediated augmentation of sonodynamic therapy efficacy and antitumor immunity, Nature Communications, vol. 14, 6973, 2023
2023 Fan Zhang, Yong Kang, Liwen Feng, Guan Xi, Wei Chen, Na Kong, Wei Tao, * Tiangang Luan, * Seyoung Koo*, Xiaoyuan Ji*, Infected wound repair with an ultrasound-enhanced nanozyme hydrogel scaffold, Materials Horizons, vol. 10, 5474-5483, 2023
2023 Lee MH*, Wu PF, Chen TI, Chan C, Lin HH, Huang YH, Chen HY, Lin YT, (Chen CJ, Tenofovir use is associated with a decreased risk of hepatocellular carcinoma among men with HIV irrespective of coinfection status., JHEP reports : innovation in hepatology, vol. 5(3), 100634, 2023
2023 Yu ML, Wang CY, Lee MH, Ou HY, Cheng PN, Tu ST, Huang JF, Chen JF, Hu TH, Hsu CC, Kao JH, (Chen CJ, Lin HC*, Huang CN*, TASL, TADE, and DAROC consensus for the screening and management of hepatitis C in patients with diabetes., Journal of the Formosan Medical Association = Taiwan yi zhi, vol. 122(3), 202-220, 2023
2023 Hsieh YC, Pan MH, Jeng WJ*, Hu HH, Liu J, Mizokami M, (Chen CJ, Yang HI, Serum HBcrAg and Hepatocellular Carcinoma in a Taiwanese Population Seronegative for HBsAg and Anti-HCV., Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 21(5), 1303-1313.e11, 2023
2023 Hsu CC*, Gopalakrishna H, Mironova M, Lee MH, (Chen CJ, Yang HI, Wiese M, Chang KM, Wright EC, Abijo T, Feld JJ*, Kaplan DE, Risk of Hepatocellular Carcinoma After Spontaneous Clearance of Hepatitis C Virus and in Noncirrhosis Chronic Hepatitis C Patients With Sustained Virological Response: A Systematic Review., Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 77(Suppl 3), S245-S256, 2023
2023 Lam WKJ, King AD, Miller JA, Liu Z, Yu KJ, Chua MLK, Ma BBY, Chen MY, Pinsky BA, Lou PJ, Woo JKS, Hsu WL, Simon J, Doolan DL, Waterboer T, Hui EP, Li H, Tsang RK, Wong KCW, Goh JP, Vlantis AC, Ai QY, Wong LM, Abdullah V, Lin JC, (Chen CJ, Pfeiffer RM, Le QT, Lee AWM, Ji M, Cao S, Ma J, Chan ATC, Chan KCA*, Hildesheim A, Recommendations for Epstein-Barr virus-based screening for nasopharyngeal cancer in high- and intermediate-risk regions., Journal of the National Cancer Institute, vol. 115(4), 355-364, 2023
2023 Lin HC, Liu J, Pan MH, Lee MH, Batrla-Utermann R, Lu SN, Jeng WJ, Yang HI*, (Chen CJ, Rapid Decline Rather Than Absolute Level of HBsAg Predicts Its Seroclearance in Untreated Chronic Hepatitis B Patients From Taiwanese Communities., Clinical and translational gastroenterology, vol. 14(8), e00586, 2023
2023 Blechter B*, Chien LH, Chen TY, Chang IS, Choudhury PP, Hsiao CF, Shu XO, Wong JYY, Chen KY, Chang GC, Tsai YH, Su WC, Huang MS, Chen YM, Chen CY, Hung HH, Hu JW, Shi J, Zheng W, Rositch AF, (Chen CJ, Chatterjee N, Yang PC, Rothman N, Hsiung CA, Lan Q, Polygenic Risk Score, Environmental Tobacco Smoke, and Risk of Lung Adenocarcinoma in Never-Smoking Women in Taiwan., JAMA network open, vol. 6(11), e2339254, 2023
2023 Chien RN, Lu SN, Hui-Min Wu G, Yang WW, Pwu RF, Liu CL, Cheng KP, Chen SC, (Chen CJ*, Policy and Strategy for Hepatitis C Virus Elimination at the National Level: Experience in Taiwan., The Journal of infectious diseases, vol. 228(Suppl 3), S180-S188, 2023
2023 Lou PJ, Jacky Lam WK, Hsu WL, Pfeiffer RM, Yu KJ, Chan CML, Lee VCT, Chen TC, Terng SD, Tsou YA, Leu YS, Liao LJ, Chang YL, Chien YC, Wang CP, Lin CY, Hua CH, Lee JC, Yang TL, Hsiao CH, Wu MS, Tsai MH, Cheng HC, Hildesheim A, (Chen CJ, Chan KCA*, Liu Z, Performance and Operational Feasibility of Epstein-Barr Virus-Based Screening for Detection of Nasopharyngeal Carcinoma: Direct Comparison of Two Alternative Approaches., Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 41(26), 4257-4266, 2023
2023 Liao PJ, Lee CH, Wang SL, Chiou HY, (Chen CJ, Seak CJ, Wu IW, Hsu KH*, Low-to-Moderate Arsenic Exposure and Urothelial Tract Cancers with a Long Latent Period of Follow-Up in an Arseniasis Area., Journal of epidemiology and global health, vol. 13(4), 807-815, 2023
2023 Wang CL, Hsu KH, Chang YH, Ho CC, Chiang CJ, Chen KC, Cheung YC, Huang PC, Chen YR, Chen CY, Hsu CP, Hsia JY, Chen HY, Yang SY, Li YJ, Yang TY, Tseng JS, Chuang CY, Hsiung CA, Chen YM, Huang MS, Yu CJ, Chen KY, Su WC, Chen JJW, Yu SL, (Chen CJ, Yang PC, Tsai YH, Chang GC*, Low-Dose Computed Tomography Screening in Relatives With a Family History of Lung Cancer., Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, vol. 18(11), 1492-1503, 2023