Selected Publications

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Year Paper Title
2014 Yang YF, Jan YH, Liu YP, Yang CJ, Su CY, Chang YC, Lai TC, Chiou J, Tsai HY, (Lu J, Shen CN, Shew JY, Lu PJ, Lin YF, Huang MS, Hsiao M, Squalene synthase induces tumor necrosis factor receptor 1 enrichment in lipid rafts to promote lung cancer metastasis., American journal of respiratory and critical care medicine, vol. 190(6), 675-687, 2014
2014 Liu SM, (Lu J, Lee HC, Chung FH, Ma N, miR-524-5p suppresses the growth of oncogenic BRAF melanoma by targeting BRAF and ERK2., Oncotarget, vol. 5(19), 9444-9459, 2014
2014 Liu YC, Kao YT, Huang WK, Lin KY, Wu SC, Hsu SC, Schuyler SC, Li LY, Leigh Lu F, (Lu J*, CCL5/RANTES is important for inducing osteogenesis of human mesenchymal stem cells and is regulated by dexamethasone., Bioscience trends, vol. 8(3), 138-143, 2014
2014 Huang HN, Chen SY, Hwang SM, Su MW, Mai W, Wang HW, Cheng WC, Schuyler SC, Ma N, Lu FL, (Lu, J.)*, miR-200c and GATA binding protein 4 regulate human embryonic stem cell renewal and differentiation, Stem Cell Research, vol. 12(2), 338-353, 2014
2014 Chang, C.F., Hsu, K.H., Shen, C.N., Li, C.L.*, Lu, J.)*, Enrichment and characterization of two subgroups of committed osteogenic cells in the mouse endosteal bone marrow with expression levels of CD24, Journal of Bone Research, vol. 2, 144, 2014
2014 Chen, J.-R., Yu, Y.-H., Tseng, Y.-C., Chiang, W.-L., Chiang, M.-F., Ko, Y.-A., Chiu, Y.-K., Ma, S.-H., Wu, C.-Y., Jan, J.-T., (Lin, K.-I)*, Ma, C.*, Wong, C.-H.*, Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against Influenza virus infections, Proceedings of the National Academy of Sciences of the United States of America, vol. 111(7), 2476-2481, 2014
2014 Lin, M.-H., Yeh, L.-T., Chen, S.-J., Chiou, H.-Y., Chu, C.-C., Yen, L. B., (Lin, K.-I, Chang, D.-M., Sytwu, H.-K., T cell-specific BLIMP-1 deficiency exacerbates experimental autoimmune encephalomyelitis in nonobese diabetic mice by increasing Th1 and Th17 cells, CLINICAL IMMUNOLOGY, vol. 151(2), 101-113, 2014
2014 Lin, I-Y., Chiu, F.-L., Yeang, C.-H., Chen, H.-F., Chuang, C.-Y., Yang, S.-Y., Hou, P.-S., Sintupisut, N., Ho, H.-N., Kuo, H.-C.*, Lin, K.-I)*, Suppression of the SOX2 neural effector gene by PRDM1 promotes human germ cell fate in embryonic stem cells, Stem Cell Reports, vol. 2(2), 189-204, 2014
2014 Huang, K.-Y.; Wu, H.-Y.; Chen, Y.-J.; Lu, C.-T.; Su, M.-G.; Hsieh, Y.-C.; Tsai, C.-M.; (Lin, K.-I); Huang, H.-D.; Lee, T.-Y., Chen, Y.-J, RegPhos 2.0: an updated resource to explore protein kinase-substrate phosphorylation networks in mammals., Database-The Journal of Biological Databases and Curation, vol. bau034, 2014
2014 Tsai, C.-M. Wu, H.-Y., Su, T.-H., Kuo, C.-W., Huang, H.-W., Chung, C.-H., Chen, C.-S., Khoo, K.-H., Chen, Y.-J.*, Lin, K.-I)*, Phosphoproteomic analyses reveal that galectin-1 augments the dynamics of B-cell receptor signaling, Journal of Proteomics, vol. 103, 241-253, 2014
2014 Chiu, Y.-K., Lin, I-Y., Su, S.-T., Wang, K.-H., Yang, S.-Y., Tsai, D.-Y., Hsieh, Y.-T., Lin, K.-I)*, Transcription factor ABF-1 suppresses plasma cell differentiation but facilitates memory B cell formation, JOURNAL OF IMMUNOLOGY, vol. 193(5), 2207-2217, 2014
2014 Kretzschmar, K., Cottle, D.L., Donati, G, Chiang, M.-F., Quist, S.R., Gollnick, H.P., Natsuga, K., Aoyagi, S., (Lin, K.-I, Watt, F. M., BLIMP1 does not define a sebaceous gland progenitor population but is required for epidermal homeostasis, Stem Cell Reports, vol. 3(4), 620-633, 2014
2014 C. Y. Chang, S. Y. Lyu, Y. C. Liu, N. S. Hsu, C. C. Wu, C. F. Tang, K. H. Lin, J. Y. Ho, C. J. Wu, M. D. Tsai, T. L. Li*, Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 53(7), 1943-1948, 2014
2014 K. C. Wang, S. Y. Lyu, Y. C. Liu, C. Y. Chang, C. J. Wu, T. L. Li*, Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple-reaction complexes, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 70(5), 1401-1410, 2014
2014 X. W. Zou, Y. C. Liu, N. S. Hsu, C. J. Huang, S. Y. Lyu, H. C. Chan, C. Y. Chang, H. W. Yeh, K. H. Lin, C. J. Wu, M. D. Tsai, T. L. Li*, Structure and mechanism of a non-heme iron-SAM dependent C-methyltransferase and its engineering to hydratase and O-methyltransferase, ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, vol. 70(6), 1549-1560, 2014
2014 S. Y. Lyu, Y. C. Liu, C. Y. Chang, C. J. Huang, Y. H. Chiu, C. M. Huang, N. S. Hsu, K. H. Lin, C. J. Wu, M. D. Tsai, T. L. Li*, Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics effectively killing vancomycin-resistant Enterococcus, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 136(31), 10989-10995, 2014
2014 Chu CS, Lo PW, Yeh YH, Hsu PH, Peng SH, Teng YC, Kang ML, Wong CH*, (Juan LJ)*, O-GlcNAcylation regulates EZH2 protein stability and function., Proceedings of the National Academy of Sciences of the United States of America, vol. 111(4), 1355-60, 2014
2014 Huang, T.-Y.; Zulueta, M. M. L.; (Hung, S.-C., Regioselective One-pot Protection, Protection-Glycosylation and Protection- Glycosylation-Glycosylation of Carbohydrates: A Case Study with D-Glucose, Organic & Biomolecular Chemistry, vol. 12(2), 376-382, 2014
2014 Patil, P. S.; Zulueta, M. M. L.; (Hung, S.-C., Synthesis of Phosphatidylinositol Mannosides, Journal of the Chinese Chemical Society, vol. 61, 151-162, 2014
2014 Hsu Y; Ma HH; Lico LS; Jan JT; Fukase K; Uchinashi Y; Zulueta MM; (Hung SC.*, One-pot synthesis of N-acetyl- and N-glycolylneuraminic acid capped trisaccharides and evaluation of their influenza A(H1N1) inhibition., ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 53, 2413-2416, 2014
2014 Li YC; Ho IH; Ku CC; Zhong YQ; Hu YP; Chen ZG; Chen CY; Lin WC; Zulueta MM; (Hung SC*); Lin MG; Wang CC; (Hsiao CD*, Interactions That Influence the Binding of Synthetic Heparan Sulfate Based Disaccharides to Fibroblast Growth Factor-2, ACS Chem Biol., vol. 9, 1912-1717, 2014
2014 Chang CH; Lico LS; Huang TY; Lin SY; Chang CL; Arco SD; (Hung SC.*, Synthesis of the heparin-based anticoagulant drug Fondaparinux., ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 53, 9876-9879, 2014
2014 Ko YC; Tsai CF; Wang CC*; Dhurandhare VM; Hu PL; Su TY; Lico LS; Zulueta MM; (Hung SC*, Microwave-assisted one-pot synthesis of 1,6-anhydrosugars and orthogonally protected thioglycosides., J Am Chem Soc., vol. 136, 14425-14431, 2014
2014 Feng-Chi Chen*, (Trees-Juen Chuang)*, Hsuan-Yu Lin, Min-Kung Hsu, The evolution of the coding exome of the Arabidopsis species - the influences of DNA methylation, relative exon position, and exon length, BMC EVOLUTIONARY BIOLOGY, vol. 14, 145, 2014
2014 Chun-Ying Yu, Hsiao-Jung Liu, Li-Yuan Hung, Hung-Chih Kuo*, Trees-Juen Chuang)*, Is an Observed Non-co-linear RNA Product Spliced in trans, in cis, or just in vitro?, NUCLEIC ACIDS RESEARCH, vol. 42(14), 9410-9423 (Corresponding & first author; SCI impact factor: 10.162; Rank (BIOCHEMISTRY & MOLECULAR BIOLOGY): 14/286; Q1), 2014
2014 Chan-Shuo Wu, Chun-Ying Yu, Ching-Yu Chuang, Michael Hsiao, Cheng-Fu Kao, Hung-Chih Kuo*, Trees-Juen Chuang)*, Integrative transcriptome sequencing identifies trans-splicing events with important roles in human embryonic stem cell pluripotency, Genome Research, vol. 24(1), 25-36 (impact factor: 10.101; ranking: 3/160: BIOTECHNOLOGY & APPLIED MICROBIOLOGY), 2014
2014 Trees-Juen Chuang)*, Feng-Chi Chen*, DNA methylation is associated with an increased level of conservation at nondegenerate nucleotides in mammals, Molecular Biology and Evolution, vol. 31(2), 387-396 (impact factor: 10.217; ranking: 14/290: BIOCHEMISTRY & MOLECULAR BIOLOGY), 2014
2014 Trees-Juen Chuang)*, Tai-Wei Chiang, Impacts of Pre-transcriptional DNA Methylation, Transcriptional Transcription Factor and Post-transcriptional microRNA Regulations on Protein Evolutionary Rate, Genome Biology and Evolution, vol. 6(6), 1530-1541, 2014
2014 Hsu CH, Schelwies M, Enck S, Huang LY, Huang SH, Chang YF, Cheng TJ, Cheng WC, Wong CH, Iminosugar C-Glycoside Analogues of alpha-d-GlcNAc-1-Phosphate: Synthesis and Bacterial Transglycosylase Inhibition., The Journal of organic chemistry, vol. 79(18), 8629-8637, 2014
2014 Huang LY, Huang SH, Chang YC, Cheng WC, Cheng TJ, Wong CH, Enzymatic Synthesis of Lipid II and Analogues., Angewandte Chemie-International Edition, vol. 53(31), 8060-8065, 2014