Selected Publications

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Year Paper Title
2014 Chang YW, Chen MW, Chiu CF, Hong CC, Cheng CC, (Hsiao M)*, Chen CA, Wei LH, Su JL, Arsenic trioxide inhibits CXCR4-mediated metastasis by interfering miR-520h/PP2A/NF-kappaB signaling in cervical cancer, Ann Surg Oncol, vol. 21(Suppl 4), 687-695, 2014
2014 J.-R. Chen, Y.-H. Yu, Y.-C. Tseng, W.-L. Chiang, M.-F. Chiang, Y.-A. Ko, Y.-K. Chiu, S.-H. Ma, C.-Y. Wu, J.-T. Jan, K.-I. Lin, C. Ma, C.-H. Wong, Vaccination of monoglycosylated hemagglutinin induces cross-strain protection against influenza virus infections, Proceedings of the National Academy of Sciences of the United States of America, vol. 111 (7), 2476-2481, 2014
2014 J. Lin, Y.-J. Chang, W.-B. Yang, A. L. Yu, C.-H. Wong, The Multifaceted Effects of Polysaccharides Isolated from Dendrobium huoshanense on Immune Functions with the Induction of Interleukin-1 Receptor Antagonist (IL-1ra) in Monocytes., PloS one, vol. 9(4), e94040, 2014
2014 C.-L. Chen, T.-C. Lin, S.-Y. Wang, J.-J. Shie, K.-C. Tsai, Y.-S. E. Cheng, J.-T. Jan, C.-J. Lin, J.-M. Fang, C.-H. Wong, Tamiphosphor Monoesters as Effective Anti-influenza Agents, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 81, 106-118, 2014
2014 Y.-W. Lou, P.-Y. Wang, S.-C. Yeh, P.-K. Chuang, S.-T. Li, C.-Y. Wu, K.-H. Khoo, M. Hsiao, T.-L. Hsu, C.-H. Wong, Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers, Proceedings of the National Academy of Sciences of the United States of America, vol. 111 (7), 2482-2487, 2014
2014 C.-Y. Wang, C.-Y. Wu, T.-J. Hung, C.-H. Wong, C.-H. Chen, Sequence-constructive SELEX: A new strategy for screening DNA aptamer binding to Globo H., Biochemical and biophysical research communications, vol. 452(3), 484-489, 2014
2014 P.-C. Chen, P.-K. Chuang, C.-H. Chen, J.-R. Chen, S.-W. Lin, C. Ma, T.-L. Hsu, C.-H. Wong, Role of N-linked glycans in the interactions of recombinant HCV envelope glycoproteins with cellular receptors., ACS chemical biology, vol. 9(7), 1437-1443, 2014
2014 J.-T. Hung, Y.-C. Tsai, W.-D. Lin, J.-T. Jan, K.-H. Lin, J.-R. Huang, J.-Y. Cheng, M.-W. Chen, C.-H. Wong, A. L. Yu, Potent adjuvant effects of novel NKT stimulatory glycolipids on hemagglutinin based DNA vaccine for H5N1 influenza virus., Antiviral research, vol. 107, 110-118, 2014
2014 B.-T. Hong, C.-L. Chen, Jim-Min Fang, Shi-Yun Wang, Wen-I Huang, Yih-Shyun E. Cheng, Chi-Huey Wong, Oseltamivir Hydroxamate and Acyl Sulfonamide Derivatives as Influenza Neuraminidase Inhibitors, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22(23), 6647-6654, 2014
2014 C.-S. Chu, P.-W. Lo, Y.-H. Yeh, P.-H. Hsu, S.-H. Peng, Y.-C. Teng, M.-L. Kang, C.-H. Wong, L.-J. Juan, O-GlcNAcylation regulates EZH2 protein stability and function., Proceedings of the National Academy of Sciences of the United States of America, vol. 111(4), 1355-1360, 2014
2014 H.-Y. Lee, C.-Y. Chen, T.-I. Tsai, S.-T. Li, K.-H. Lin, Y.-Y. Cheng, C.-T. Ren, T.-J. Cheng, C.-Y. Wu, C.-H. Wong, Immunogenicity study of Globo H derivatives with modification at the reducing or non-reducing end of the tumor antigen, J. Am. Chem. Soc., vol. 136(48), 16844-16853, 2014
2014 C.-H. Hsu, M. Schelwies, S. Enck, L.-Y. Huang, S.-H. Huang, Y.-F. Chang, T.-J. Cheng, W.-C. Cheng, C.-H. Wong, Iminosugar C-Glycoside Analogues of alpha-d-GlcNAc-1-Phosphate: Synthesis and Bacterial Transglycosylase Inhibition., The Journal of organic chemistry, vol. 79(18), 8629-8637, 2014
2014 S.-C. Lin, W.-C. Liu, J.-T. Jan, C.-H. Wong, S.-C. Wu, Glycan Masking of Hemagglutinin for Adenovirus Vector and Recombinant Protein Immunizations Elicits Broadly Neutralizing Antibodies against H5N1 Avian Influenza Viruses, PLoS One, vol. 9(3), e92822, 2014
2014 L.-Y. Huang, S.-H. Huang, Y.-C. Chang, W.-C. Cheng, T.-J. R. Cheng, C.-H. Wong, Enzymatic Synthesis of Lipid II and Analogues., Angewandte Chemie-International Edition, vol. 53(31), 8060-8065, 2014
2014 Y.-Y. Tseng, J.-M. Liou, T.-L. Hsu, W.-C. Cheng, M.-S. Wu, C.-H. Wong, Development of bacterial transglycosylase inhibitors as new antibiotics: Moenomycin A treatment for drug-resistant Helicobacter pylori., Bioorganic & medicinal chemistry letters, vol. 24(11), 2412-2414, 2014
2014 J.-M. Fang, Y.-S. Chen, H.-M. Yu, J.-J. Shie, T.-J. R. Cheng, C.-Y. Wu, C.-H. Wong, Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity., Bioorganic & medicinal chemistry, vol. 22(5), 1766-1772, 2014
2014 A.-K. Sauer, C.-H. Liang, J. Stech, B. Peeters, P. Quéré, C. Schwegmann-Wessels, C.-Y. Wu, C.-H. Wong, G. Herrler, Characterization of the sialic Acid binding activity of influenza a viruses using soluble variants of the h7 and h9 hemagglutinins., PloS one, vol. 9(2), e89529, 2014
2014 E. Falkowska, A. Ramos, K. J. Doores, J. H. Lee, C. Blattner, A. Ramirez, R. Derking, M. J. van Gils, C.-H. Liang, R. Mcbride, S. S. Shivatare, C.-Y. Wu, P.-Y. Chan-Hui, Y. Liu, T. Feizi, M. B. Zwick, W. C. Koff, M. S. Seaman, K. Swiderek, J. P. Moore, J. C. Paulson, C.-H. Wong, A. B. Ward, I. A. Wilson, R. W. Sanders, P. Poignard, D. R. Burton, Broadly Neutralizing HIV Antibodies Define a Glycan-Dependent Epitope on the Prefusion Conformation of gp41 on Cleaved Envelope Trimers., Immunity, vol. 40(5), 657-668, 2014
2014 J.-J. Shie, Y.-C. Liu, Y.−M. Lee, C. Lim, J.-M. Fang, C.-H. Wong, An azido-BODIPY probe for glycosylation: initiation of strong fluorescence upon triazole formation, Journal of the American Chemical Society, vol. 136 (28), 9953-9961, 2014
2014 J -R. Huang, Y.-C. Tsia, Y.-J. Chang, J.-C. Wu, J.-T. Hung, K.-H. Lin, C.-H. Wong, Alice L. Yu, alpha-Galactosylceramide but Not Phenyl-Glycolipids Induced NKT Cell Anergy and IL-33-Mediated Myeloid-Derived Suppressor Cell Accumulation via Upregulation of egr2/3., Journal of immunology, vol. 192(4), 1972-1981, 2014
2014 JJ Lee, CY Yeh, CJJung, CW Chen, MK Du, HM Yu, CJ Yang, HY Lin, Andy Sun, JY Ko, SJ Cheng, YL Chang, JS Chia, Skewed distribution of IL-7 receptor-α-expressing effector memory CD8+ T cells with distinct functional characteristics in oral squamous cell carcinoma Short title: IL-7R-α-expressing CD8+ T in oral cancer, PLoS One, vol. 9(1), e85521, 2014
2014 YS, Chen, HM Yu, JJ Shie, TJ R. Cheng, CY Wu, JM Fang, CH Wong, Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity, Bioorganic & Medicinal Chemistry, vol. 22, 1766-1772, 2014
2014 Yow-Fu Tsai*, Yu-Fa Wu, Jhe-Ruei Guo, Cheng-Ping Yu, Chun-Chen Liao, First total synthesis of ganglioside DSG-A possessing neuritogenic activity, Org. Biomol. Chem., vol. 12(46), 9345-9349, 2014
2014 Lou YW, Wang PY, Yeh SC, Chuang PK, Li ST, Wu CY, Khoo KH, Hsiao M, Hsu TL, Wong CH, Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers., Proceedings of the National Academy of Sciences of the United States of America, vol. 111(7), 2482-2487, 2014
2014 Chen PC, Chuang PK, Chen CH, Chan YT, Chen JR, Lin SW, Ma C, Hsu TL, Wong CH, Role of N-Linked Glycans in the Interactions of Recombinant HCV Envelope Glycoproteins with Cellular Receptors., ACS chemical biology, vol. 9(7), 1437-1443, 2014
2014 Tseng YY, Liou JM, Hsu TL, Cheng WC, Wu MS, Wong CH, Development of bacterial transglycosylase inhibitors as new antibiotics: Moenomycin A treatment for drug-resistant Helicobacter pylori., Bioorganic & medicinal chemistry letters, vol. 24(11), 2412-2414, 2014
2014 •Chen CJ, Hsu WL, Yang HI, Lee MH, Chen HC, Chien YC, You SL, Epidemiology of virus infection and human cancer, RECENT RESULTS IN CANCER RESEARCH, vol. 193, 11-32, 2014
2014 Chien YC, Jan CF, Chiang CJ, Liu CJ, Kuo HS, You SL, Chen CJ., Incomplete Hepatitis B Immunization, Maternal Carrier Status and Increased Risk of Liver Diseases: A 20-year Cohort Study of 3.8 Million Vaccinees, HEPATOLOGY, vol. 60(1), 125-132, 2014
2014 Hsu WL, Chien YC, Chiang CJ, Yang HI, Lou PJ, Wang CP, Yu KJ, You SL, Wang LY, Chen SY, Yang CS, Chen CJ., Lifetime Risk of Distinct Upper Aerodigestive Tract Cancers and Consumption of Alcohol, Betel and Cigarette, INTERNATIONAL JOURNAL OF CANCER, vol. 135(6), 1480-1486, 2014
2014 Lee HY, Chen CY, Tsai TI, Li ST, Lin KH, Cheng YY, Ren CT, Cheng TJ, Wu CY, Wong CH, Immunogenicity study of Globo H analogues with modification at the reducing or nonreducing end of the tumor antigen., Journal of the American Chemical Society, vol. 136(48), 16844-53, 2014