具代表性研究發表

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年度 論文名稱
2020 Chan MH, Chan YC, Liu RS, (Hsiao M)*, A selective drug delivery system based on phospholipid-type nanobubbles for lung cancer therapy, Nanomedicine, vol. Nov;15(27), 2689-2705, 2020
2020 Chang YX, Lin YF, Chen CL, Huang MS, (Hsiao M, Liang PH, Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3β-β-catenin and XIAP-Survivin Pathways, Cancers, vol. 12(12), 3865, 2020
2020 Pikatan NW, Liu YL, Bamodu OA, (Hsiao M, Hsu WM, Haryana SM, Sutaryo S, Chao TY, Yeh CT, Aberrantly expressed Bruton’s tyrosine kinase preferentially drives metastatic and stem cell-like phenotypes in neuroblastoma cells, Cellular Oncology, vol. 43(6):1067-1084, 2020
2020 C.-F. Huang, W.-H. Chang, T.-K. Lee, Y. Joti, Y. Nishino, T. Kimura, A. Suzuki, Y. Bessho, T.-T. Lee, M.-C. Chen, S.-M. Yang, Y. Hwu, S.-H. Huang, P.-N. Lee, P. Chen, Y.-C. Tseng, C. Ma, T.-L. Hsu, K. Tono, T. Ishikawa, K. Liang, XFEL coherent diffraction imaging for weakly scattering particles using heterodyne interference, AIP Advances, vol. 10(5), 055219, 2020
2020 L.-T. Chiu, N. Sabbavarapu, W.-C. Lin, C.-Y. Fang, C.-C. Wu, T.-J. Cheng, S.-C. Hung, Trisaccharide Sulfate and Its Sulfonamide as an Effective Substrate and Inhibitor of Human Endo-O-sulfatase-1, Journal of the American Chemical Society, vol. 142(11), 5282-5292, 2020
2020 S. Shivatare, Synthetic Carbohydrate Chemistry and Translational Medicine., The Journal of organic chemistry, vol. 85(24), 15780-15800, 2020
2020 S. Pawar, L. Hsu, T. N. Reddy, M. Ravinder, C.-T. Ren, Y.-W. Lin, Y.-Y. Cheng, T.-W. Lin, T.-L. Hsu, S.-K. Wang, C.-Y. Wu, Synthesis of Asymmetric N-Glycans as Common Core Substrates for Structural Diversification through Selective Enzymatic Glycosylation, ACS Chemical Biology, vol. 15(9), 2382-2394, 2020
2020 C.-Y. Lin, H.-Y. Wu, P.-S. Wu, Y.-L. Hsu, T.-J. Cheng, J.-H. Liu, R.-J. Huang, T. H. Hsiao, C.-J. Wang, P.-F. Hung, A. Lan, Y.-J. Chen, S.-H. Pan, R.-J. Chein, P.-C. Yang, Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein, Journal of Medicinal Chemistry, vol. 63(6), 3172-3187, 2020
2020 C.-W. Cheng, C.-Y. Wu, W.-L. Hsu, Programmable One-Pot Synthesis of Oligosaccharides, Biochemistry, vol. 59(34), 3078-3088, 2020
2020 S. Dey, H.-J. Lo, Programmable One-Pot Synthesis of Heparin Pentasaccharide Fondaparinux, Organic Letters, vol. 22(12), 4638-4642, 2020
2020 E. A. Wang, W.-Y. Chen, Multiple Growth Factor Targeting by Engineered Insulin-like Growth Factor Binding Protein-3 Augments EGF Receptor Tyrosine Kinase Inhibitor Efficacy, Scientific Reports, vol. 10(1), 2735, 2020
2020 C.-Y. Wu, H.-Y. Chuang, Influenza virus neuraminidase regulates host CD8(+) T-cell response in mice., Communications biology, vol. 3(1), 748, 2020
2020 W.-F. Wang, M.-Y. Jade Lu, T.-J. R. Cheng, Y.-C. Tang, Y.-C. Teng, T.-Y. Hwa, Y.-H. Chen, M.-Y. Li, M.-H. Wu, P.-C. Chuang, R. Jou, W.-H. Li, Genomic Analysis of Mycobacterium tuberculosis Isolates and Construction of a Beijing Lineage Reference Genome, Genome Biology and Evolution, vol. 12(2), 3890-3905, 2020
2020 J. Woodring, S.-H. Lu, L. Krasnova, S.-C. Wang, J.-B. Chen, C.-C. Chou, Y.-C. Huang, T.-J. Cheng, Y.-T. Wu, Y.-H. Chen, J.-M. Fang, M.-D. Tsai, Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein, Journal of Medicinal Chemistry, vol. 63(1), 205-215, 2020
2020 Y.-H. Chang, J.-C. Wu, H.-M. Yu, H.-T. Hsu, Y.-T. Wu, A. L.-T. Yu, C.-D. T. Yu, Design and synthesis of glyco-peptides as anti-cancer agents targeting thrombin-protease activated receptor-1 interaction, Chemical Communications, vol. 56(43), 5827-5830, 2020
2020 H.-Y. Liao, S.-C. Wang, Y.-A. Koa, K.-I. Lin, C. Ma, T.-J. R. Cheng, Chimeric hemagglutinin vaccine elicits broadly protective CD4 and CD8 T cell responses against multiple influenza strains and subtypes, Proceedings of the National Academy of Sciences, vol. 117(30), 17757-17763, 2020
2020 Y.-M. Liu, M. Shahed-Al-Mahmud, X. Chen, T.-H. Chen, K.-S. Liao, J. M. Lo, Y.-M Wu., M.-C. Ho, C.-Y. Wu, J.-T. Jan, C. Ma, A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2, Cell Reports, vol. 32(6), 108016, 2020
2020 Hsieh CF, Jheng JR, Lin GH, Chen YL, Ho JY, Liu CJ, Hsu KY, Chen YS, Chan YF, (Yu HM, Hsieh PW, Chern JH, Horng JT, Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors., Emerging microbes & infections, vol. 9(1), 1194-1205, 2020
2020 Chang YH, Wu JC, (Yu HM, Hsu HT, Wu YT, Yu AL, Yu CT, Wong CH, Design and synthesis of glyco-peptides as anti-cancer agents targeting thrombin-protease activated receptor-1 interaction., Chemical communications (Cambridge, England), vol. 56(43), 5827-5830, 2020
2020 Hung WT, Chen YT, Chen CH, Lee YC, Fang JM, (Yang WB*, Flow Chemistry System for Carbohydrate Analysis by Rapid Labeling of Saccharides after Glycan Hydrolysis., SLAS technology, vol. 25(4), 356-366, 2020
2020 Chen CH, Lin YP, Ren CT, Shivatare SS, Lin NH, Wu CY, Chen CH, (Lin JL*, Enhancement of fucosylated N-glycan isomer separation with an ultrahigh column temperature in porous graphitic carbon liquid chromatography-mass spectrometry., Journal of chromatography. A, vol. 1632, 461610, 2020
2020 Lin JL, Chu ML, Chen CH, A portable multiple ionization source biological mass spectrometer., The Analyst, vol. 145(10), 3495-3504, 2020
2020 Huang Chi-Feng, Chang Wei-Hau, Lee Ting-Kuo, Joti Yasumasa, Nishino Yoshinori, Kimura Takashi, Suzuki Akihiro, Bessho Yoshitaka, Lee Tsung-Tse, Chen Mei-Chun, Yang Shun-Min, Hwu Yeukuang, Huang Shih-Hsin, Li Po-Nan, Chen Peilin, Tseng Yung-Chieh, Ma Che, Hsu Tsui-Ling, Wong Chi-Huey, Tono Kensuke, Ishikawa Tetsuya, Liang Keng S., XFEL coherent diffraction imaging for weakly scattering particles using heterodyne interference, AIP Advances, vol. 10(5) 055219, 2020
2020 Ming-Hsuan Lee, Tsui-Ling Hsu, Jinn-Jy Lin, Yu-Ju Lin, Yi-Ying Kao, Jui-Jen Chang, Wen-Hsiung Li*, Constructing a human complex type N-linked glycosylation pathway in Kluyveromyces marxianus, PLOS ONE, vol. 15(5), e0233492, 2020
2020 Pawar Sujeet, Hsu Li, Narendar Reddy Thatikonda, Ravinder Mettu, Ren Chien-Tai, Lin Yu-Wei, Cheng Yang-Yu, Lin Tzu-Wen, Hsu Tsui-Ling, Wang Sheng-Kai, Wong Chi-Huey, Wu Chung-Yi, Synthesis of Asymmetric N-Glycans as Common Core Substrates for Structural Diversification through Selective Enzymatic Glycosylation, ACS Chemical Biology, vol. 15(9), 2382-2394, 2020
2020 Jiang Min-Chao, Hu Chung-Chi, Hsu Wei-Li, Hsu Tsui-Ling, Lin Na-Sheng, Hsu Yau-Heiu, Fusion of a Novel Native Signal Peptide Enhanced the Secretion and Solubility of Bioactive Human Interferon Gamma Glycoproteins in Nicotiana benthamiana Using the Bamboo Mosaic Virus-Based Expression System, Frontiers in Plant Science, vol. 11, 594758, 2020
2020 Chiu LT, Sabbavarapu NM, Lin WC, Fan CY, Wu CC, (Cheng TR, Wong CH, Hung SC, Trisaccharide Sulfate and Its Sulfonamide as an Effective Substrate and Inhibitor of Human Endo-O-sulfatase-1., Journal of the American Chemical Society, vol. 142(11), 5282-5292, 2020
2020 Lin CY, Wu HY, Hsu YL, (Cheng TR, Liu JH, Huang RJ, Hsiao TH, Wang CJ, Hung PF, Lan A, Pan SH, Chein RJ, Wong CH, Yang PC, Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein., Journal of medicinal chemistry, vol. 63(6), 3172-3187, 2020
2020 Wang WF, Lu MJ, (Cheng TR, Tang YC, Teng YC, Hwa TY, Chen YH, Li MY, Wu MH, Chuang PC, Jou R, Wong CH, Li WH, Genomic Analysis of Mycobacterium tuberculosis Isolates and Construction of a Beijing Lineage Reference Genome., Genome biology and evolution, vol. 12(2), 3890-3905, 2020
2020 Woodring JL, Lu SH, Krasnova L, Wang SC, Chen JB, Chou CC, Huang YC, Cheng TR, Wu YT, Chen YH, Fang JM, Tsai MD, Wong CH, Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein, Journal of medicinal chemistry, vol. 63(1), 205-215, 2020