Key Achievements

Key Achievements

• 
  2022-09-01 Key Achievements

  CLEC5A is critical in Pseudomonas aeruginosa–induced NET formation and acute lung injury

  Shie-Liang Hsieh
  JCI insight

• 
  2022-08-25 Key Achievements

  Hyperphosphorylation-Mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric Stage

  Yun-Ru, Chen
  ACS Chemical Neuroscience

• 
  2022-08-12 Key Achievements

  Trans-genetic effects of circular RNA expression quantitative trait loci and potential causal mechanisms in autism

  Trees-Juen Chuang
  Molecular Psychiatry

• 
  2022-07-11 Key Achievements

  CLEC5A and TLR2 are critical in SARS-CoV-2-induced NET formation and lung inflammation

  Shie‑Liang Hsieh
  Journal of Biomedical Science

• 
  2022-06-01 Key Achievements

  Phosphoproteomics reveals the role of constitutive KAP1 phosphorylation by B-cell receptor signaling in chronic lymphocytic leukemia

  Kuo-I Lin
  Molecular Cancer Research

• 
  2022-05-26 Key Achievements

  Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation

  Chun-Mei Hu, Wen-Hwa Lee
  Nature Communications

• 
  2022-04-30 Key Achievements

  Differential effects of glucose and N-acetylglucosamine on genome instability

  Chun-Mei Hu, Wen-Hwa Lee
  American Journal of Cancer Research

• 
  2022-04-22 Key Achievements

  Serum soluble programmed death-1 levels predict the spontaneous HBeAg seroclearance in chronic hepatitis B

  Hwai-I Yang, Chien-Jen Chen
  Journal of Gastroenterology
  April 22, 2022

• 
  2022-04-19 Key Achievements

  Harnessing natural-product-inspired combinatorial chemistry and computation-guided synthesis to develop N-glycan modulators as anticancer agents

  Wei-Chieh Cheng, Chia-Ning Shen
  Chemical Science
  April 19, 2022

• 
  2022-04-06 Key Achievements

  Acute-phase serum amyloid A for early detection of hepatocellular carcinoma in cirrhotic patients with low AFP level

  Yun-Ru Chen
  Scientific Reports