Glycoengineering for a Universal COVID-19 Vaccine

  • 2024-10-30

Exosomal miRNA 16-5p/29a-3p from pancreatic cancer induce adipose atrophy by inhibiting adipogenesis and promoting lipolysis
 

Chi-Huey Wong
Scientia
October 30, 2024

The SARS-CoV2 surface spike protein is a rational target for COVID-19 vaccination. However, spike protein glycosylation helps the virus evade the immune system, undermining vaccination efforts against newer variants. Dr Chi-Huey Wong’s group at Academia Sinica, Taiwan, is hoping to combat this by glycoengineering protein- and mRNA-based COVID-19 vaccines.

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