Yin-Chu Chien, Ph.D.
Name Yin-Chu Chien, Ph.D.
現任 Senior Research Specialist/Scientist
所屬單位

Ph.D., Epidemiology, National Taiwan University, 2003
 
名片
專長

FACILITY MANAGEMENT / EXPERTISE:

Research and Management of the Health Cloud Research Program

Taiwan's National Health Insurance (NHI) program has been considered as one of the most successful program in the past twenty years since the program was launched in 1995. This nationwide program provides medical and healthcare services with the highest coverage rate, most comprehensive welfare, and the highest accessibility than any other health insurance programs in the world. There are increasing amount of research using sampling data from the NHI claims database have been published. It is extremely important to carry out a multidisciplinary study to integrate these nationwide scaled databases such as household registry, cancer registry, death certification, national screening projects, Taiwan Biobank, and national health insurance to construct a nationwide health database with high quality and accuracy of data. I take in charge the Research and Management of the Health Cloud Research Program in Academia Sinica. The goal of the program is to set up a National Big Health Data Center in Academia Sinica. I have good experiences in the management and analysis of large scaled health data, and have some publications in high-impact journals. I am interested in the research of applications with nationwide scaled dataset for health improvement.
EDUCATION AND POSITIONS HELD
  • 2014-present Senior Research Scientist, Genomics Research Center, Academia Sinica
  • 2011-2014 Associate Research Fellow, Molecular and Genomic Epidemiology Center, China Medical University Hospital
  • 2009 Visiting Assistant Professor, Department of Pediatrics and Human Development, MSU College of Human Medicine, USA
  • 2008-2011 Postdoctoral Fellow, Genomics Research Center, Academia Sinica
  • 2006-2008 Senior Specialist in Minister’s Office, National Science Council
  • 2005-2006 Postdoctoral Fellow, Graduate Institute of Epidemiology, National Taiwan University
  • 2003-2005 Senior Specialist in Minister’s Office, Department of Health
HONORS
  • 2002 8th Chen Kong-Pei Best Public Health Paper Award
Year Paper Title
2024 Kuo TY, Chang JC, (Chien YC, Jan CF*, The seroepidemiology of isolated core antibody against hepatitis B among Taiwanese adults - A large hospital-based study., Journal of the Formosan Medical Association = Taiwan yi zhi, vol. 123(6), 693-700, 2024任職中研院著作;
2023 Lou PJ, Jacky Lam WK, Hsu WL, Pfeiffer RM, Yu KJ, Chan CML, Lee VCT, Chen TC, Terng SD, Tsou YA, Leu YS, Liao LJ, Chang YL, (Chien YC, Wang CP, Lin CY, Hua CH, Lee JC, Yang TL, Hsiao CH, Wu MS, Tsai MH, Cheng HC, Hildesheim A, Chen CJ, Chan KCA, Liu Z, Performance and Operational Feasibility of Epstein-Barr Virus-Based Screening for Detection of Nasopharyngeal Carcinoma: Direct Comparison of Two Alternative Approaches., Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 41(26), 4257-4266, 2023任職中研院著作;
2023 Argirion I, Pfeiffer RM, Proietti C, Coghill AE, Yu KJ, Middeldorp JM, Sarathkumara YD, Hsu WL, (Chien YC, Lou PJ, Wang CP, Rothman N, Lan Q, Chen CJ, Mbulaiteye SM, Jarrett RF, Glimelius I, Smedby KE, Hjalgrim H, Hildesheim A, Doolan DL, Liu Z, Comparative Analysis of the Humoral Immune Response to the EBV Proteome across EBV-Related Malignancies., Cancer Epidemiology, Biomarkers & Prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol. 32(5), 687-696, 2023任職中研院著作;
2022 Hu HH, Jeng WJ, Pan MH, Luo WS, Chang CL, Huang YT, Su CY, Chiang CT, Jen CL, (Chien YC, Lu SN, Wang LY, Huang LR, Lee MH, Liu J, Nguyen MH, Chen CJ, Yang HI, Serum soluble programmed cell death 1 levels predict spontaneous functional cure in inactive carriers with chronic hepatitis B., Alimentary pharmacology & therapeutics, vol. 55(5), 558-567, 2022任職中研院著作;
2021 Lin JH, Wen CP, Jiang CQ, Yuan JM, Chen CJ, Ho SY, Gao W, Zhang W, Wang R, Chien YC, Xu L, Wu X, Jin YL, Koh WP, Hsu WL, Zhu F, Wen C, Zhu T, Lee JH, Mai ZM*, Lung ML, Lam TH, Smoking and nasopharyngeal cancer: individual data meta-analysis of six prospective studies on 334 935 men., International journal of epidemiology, vol. 50(3), 975-986, 2021任職中研院著作;
2021 Lee MH*, Huang YH, Coghill AE, Liu Z, Yu KJ, Hsu WL, Chien YC, Wang CP, Chen TC, Chen CJ, Hildesheim A, Epstein-Barr Virus-Based Nasopharyngeal Carcinoma (NPC) Risk Prediction Scores Are Elevated in NPC Multiplex Family Members in Taiwan., The Journal of infectious diseases, vol. 223(3), 441-444, 2021任職中研院著作;
2014 •Chen CJ, Hsu WL, Yang HI, Lee MH, Chen HC, Chien YC, You SL, Epidemiology of virus infection and human cancer, RECENT RESULTS IN CANCER RESEARCH, vol. 193, 11-32, 2014任職中研院著作;
2014 Chien YC, Jan CF, Chiang CJ, Liu CJ, Kuo HS, You SL, Chen CJ., Incomplete Hepatitis B Immunization, Maternal Carrier Status and Increased Risk of Liver Diseases: A 20-year Cohort Study of 3.8 Million Vaccinees, HEPATOLOGY, vol. 60(1), 125-132, 2014具代表性; 任職中研院著作;
2014 Hsu WL, Chien YC, Chiang CJ, Yang HI, Lou PJ, Wang CP, Yu KJ, You SL, Wang LY, Chen SY, Yang CS, Chen CJ., Lifetime Risk of Distinct Upper Aerodigestive Tract Cancers and Consumption of Alcohol, Betel and Cigarette, INTERNATIONAL JOURNAL OF CANCER, vol. 135(6), 1480-1486, 2014具代表性; 任職中研院著作;
2012 Hsu WL, Pan WH, Chien YC, Yu KJ, Cheng YJ, Chen JY, Liu MY, Hsu MM, Lou PJ, Chen IH, Yang CS, Hildesheim A, Chen CJ., Lowered Risk of Nasopharyngeal Carcinoma and Intake of Plant Vitamin, Fresh Fish, Green Tea and Coffee: A Case-Control Study in Taiwan , PLoS One, vol. 7(7), e41779, 2012具代表性;
2012 Hsu WL, Tse KP, Liang S, Chien YC, Su WH, Yu KJ, Cheng YJ, Tsang NM, Hsu MM, Chang KP, Chen IH, Chen TI, Yang CS, Goldstein AM, Chen CJ, Chang YS, Hildesheim A., Evaluation of Human Leukocyte Antigen-A (HLA-A), Other Non-HLA Markers on Chromosome 6p21 and Risk of Nasopharyngeal Carcinoma, PLoS One, vol. 7(8), e42767, 2012具代表性;
2011 Fwu CW, Chien YC, You SL, Nelson KE, Kirk GD, Kuo HS, Feinleib M, Chen CJ., Hepatitis B Virus Infection and Risk of Intrahepatic Cholangiocarcinoma and Non-Hodgkin Lymphoma: A Cohort Study of Parous Women in Taiwan, HEPATOLOGY, vol. 53(4), 1217-1225, 2011具代表性; 任職中研院著作;
2011 Hsu WL, Yu KJ, Chien YC, Chiang CJ, Cheng YJ, Chen JY, Liu MY, Chou SP, You SL, Hsu MM, Lou PJ, Wang CP, Hong JH, Leu YS, Tsai MH, Su MC, Tsai ST, Chao WY, Ger LP, Chen PR, Yang CS, Hildesheim A, Diehl SR, Chen CJ., Familial Tendency and Risk of Nasopharyngeal Carcinoma in Taiwan: Effects of Covariates on Risk, AMERICAN JOURNAL OF EPIDEMIOLOGY, vol. 173(3), 292-299, 2011具代表性; 任職中研院著作;
2010 Fwu CW, Chien YC, Nelson KE, Kirk GD, You SL, Kuo HS, Feinleib M, Chen CJ., Mortality after chronic hepatitis B virus infection: a linkage study of two million parous women from Taiwan, JOURNAL OF INFECTIOUS DISEASES, vol. 201(7), 1016-1023, 2010具代表性; 任職中研院著作;
2010 Jan CF, Huang KC, Chien YC, Greydanus DE, Davies HD, Chiu TY, Huang LM, Chen CJ, Chen DS., Determination of immune memory to hepatitis B vaccination through early booster response in college students, HEPATOLOGY, vol. 51(5), 1547-1554, 2010具代表性; 任職中研院著作;
2009 Hsu WL, Chen JY, Chien YC, Liu MY, Yang HI, Hsu MM, Yang CS, Chen CJ., Independent effect of EBV and cigarette smoking on nasopharyngeal carcinoma: a 20-year follow-up study on 9,622 males without family history in Taiwan, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, vol. 18(4), 1218-1226, 2009具代表性; 任職中研院著作;
2009 Fwu CW, Chien YC, Kirk GD, Nelson KE, You SL, Kuo HS, Feinleib M, Chen CJ., Hepatitis B Virus Infection and Hepatocellular Carcinoma among Parous Taiwanese Women: Nationwide Cohort Study, JNCI-Journal of the National Cancer Institute, vol. 101(14), 1019-1027, 2009具代表性; 任職中研院著作;
2006 Chien YC, Jan CF, Kuo HS, Chen CJ., Nationwide Hepatitis B Vaccination Program in Taiwan: Effectiveness in the 20 Years After it was Launched, EPIDEMIOLOGIC REVIEWS, vol. 28, 126-135, 2006具代表性;
2003 Cheng YJ, Chien YC, Hildesheim A, Hsu MM, Chen IH, Chuang J, Chang J, Ma YD, Luo CT, Hsu WL, Hsu HH, Huang H, Chang JF, Chen CJ, Yang CS., No Association Between Genetic Polymorphisms of CYP1A1, GSTM1, GSTT1, GSTP1, NAT2, and Nasopharyngeal Carcinoma in Taiwan, CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, vol. 12(2), 179-180, 2003具代表性;
2003 Chien YC, Chen CJ., Epidemiology and Etiology of Nasopharyngeal Carcinoma: Gene-Environment Interaction, CANCER REVIEWS: ASIA-PACIFIC, vol. 1(1), 1-19, 2003具代表性;
2001 Chien YC, Chen JY, Liu MY, Yang HI, Hsu MM, Chen CJ, Yang CS, Serologic Markers of Epstein-Barr Virus Infection and Nasopharyngeal Carcinoma in Taiwanese men, NEW ENGLAND JOURNAL OF MEDICINE, vol. 345(26), 1877-1882, 2001具代表性;