具代表性研究發表

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年度 論文名稱
2012 Chuang, C.-Y., (Lin, K.-I, Hsiao, M., Stone, L., Chen, H.-F., Huang, Y.-H., Lin, S.-P., Ho, H.-N., and Kuo, H.-C., Meiotic competent human germ cell-like cells derived from human embryonic stem cells induced by BMP4/WNT3A signaling and OCT4/EpCAM selection., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 287, 14389-14401, 2012
2012 Hsu Y, Lu XA, Zulueta MM, Tsai CM, (Lin KI, Hung SC, Wong CH., Acyl and Silyl Group Effects in Reactivity-Based One-Pot Glycosylation: Synthesis of Embryonic Stem Cell Surface Carbohydrates Lc(4) and IV(2)Fuc-Lc(4), J Am Chem Soc., vol. 134(10), 4549-4552, 2012
2012 Ying, H.-Y., Su, S.-T., Hsu, P.-H., Chang, C.-C., Lin, I-Y., Tseng, Y.-H., Tsai, M.-D., Shih, H.-M., Lin, K.-I*, SUMOylation of Blimp-1 is critical for plasma cell differentiation, EMBO REPORTS, vol. 13, 631-637, 2012
2012 Lin, F.-R., Huang, S.-Y., Hung, K.- H., Su, S.-T., Chung, C.-H., Matsuazwa, A., Hsiao, M., Ichijo, H., Lin, K.-I)*, ASK1 promotes apoptosis of normal and malignant plasma cells, Blood, vol. 120(5), 1039-1047, 2012
2012 Y. H. Chiu, Y. L. Chan, L. W. Tsai, T. L. Li, C. J. Wu*, Prevention of human enterovirus 71 infection by carrageenan, ANTIVIRAL RESEARCH, vol. 95, 128-134, 2012
2012 Y. H. Chiu, Y. L. Chan, T. L. Li, C. J. Wu*, Inhibition of Japanese encephalitis virus infection by the sulfated polysaccharide extracts from Ulva lactuca, MARINE BIOTECHNOLOGY, vol. 14, 468-478, 2012
2012 H. Wang, Y. L. Chan, T. L. Li, C. J. Wu*, Improving cachectic symptoms and immune strength of tumor-bearing mice in chemotherapy by a combination of Scutellaria baicalensis and Qing-Shu-Yi-Qi-Tang, EUROPEAN JOURNAL OF CANCER, vol. 48, 1074-1084, 2012
2012 H. J. Chai, Y. L. Chan, T. L. Li, C. H. Wu, Y. C. Chen, C. Y. Shiau, C. J. Wu*, Composition characterization of Myctophids (Benthosema pterotum): antioxidation and safety evaluations for Myctophids protein hydrolysates, FOOD RESEARCH INTERNATIONAL, vol. 46, 118-126, 2012
2012 S. H. Chen, D. R. Hwang, G. H. Chen, N. S. Hsu, Y. T. Wu, T. L. Li*, C. H. Wong*, Engineering transaldolase in Pichia stipitis to improve bioethanol production, ACS CHEMICAL BIOLOGY, vol. 7(3), 481-486, 2012
2012 T. L. Li*, Y. C. Liu, S. Y. Lyu, Combining biocatalysis and chemoselective chemistries for glycopeptide antibiotics modification, CURRENT OPINION IN CHEMICAL BIOLOGY, vol. 16, 170-178, 2012
2012 H. C. Wu, Y. S. Li, Y. C. Liu, S. Y. Lyu, C. J. Wu, T. L. Li*, Chain elongation and cyclization in type III PKS DpgA, CHEMBIOCHEM, vol. 13(6), 862-871, 2012
2012 T. L. Lin, F. L. Yang, A. S. Yang, H. P. Peng, T. L. Li, M. D. Tsai, S. H. Wu, J. T. Wang*, Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharide, PLOS ONE, vol. 7(10), e46783, 2012
2012 Hsu CH, Peng KL, Jhang HC, Lin CH, Wu SY, Chiang CM, Lee SC, Yu WC, (Juan LJ)*, The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription., Oncogene, vol. 31(18), 2335-49, 2012
2012 Hsu CH, Peng KL, Kang ML, Chen YR, Yang YC, Tsai CH, Chu CS, Jeng YM, Chen YT, Lin FM, Huang HD, Lu YY, Teng YC, Lin ST, Lin RK, Tang FM, Lee SB, Hsu HM, Yu JC*, Hsiao PW*, (Juan LJ)*, TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases., Cell reports, vol. 2(3), 568-79, 2012
2012 Hwang-Verslues, W.W.)*, Lee, W.-H., Lee, E.Y.-H.P., Biomarkers to target heterogeneous breast cancer stem cells (invited review), Journal of Molecular Biomarkers & Diagnosis, vol. S8, 006, 2012
2012 Chang, P.-H., (Hwang-Verslues, W.W., Chang, Y.-C., Chen, C.-C., Hsiao, M., Jeng, Y.-M., Chang, K.-J., Lee, E. Y.-H. P., Shew, J.-Y., Lee, W.-H., Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway, CANCER RESEARCH, vol. 72(18), 4652-4661, 2012
2012 Hu CM, Yeh MT, Tsao N, Chen CW, Gao QZ, Chang CY, Lee MH, Fang JM, Sheu SY, Lin CJ, Tseng MC, Chen YJ, Chang ZF, Tumor cells require thymidylate kinase to prevent dUTP incorporation during DNA repair., CANCER CELL, vol. 22, 36-50, 2012
2012 Hung, S.-C.; Lu, X.-A.; Lee, J.-C.; Fang, S.-L.; Fan, T.-C.; Chang, M. D.-T.; Zulueta, M. M. L.; Chiu, L.-T., Synthesis of Heparin Oligosaccharides and Their Interaction with Eosinophil-Derived Neurotoxin, Org. Biomol. Chem., vol. 10, 760-772, 2012
2012 Hsu, C.-Y.; Lee, I-C.; Lico, L. S.; Uang, B.-J.; Hung, S.-C., Synthesis of a Furanosyl-pyranone Derivative Related to the Tri-O-heterocyclic Core of Herbicidins, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol. 59, 421-425, 2012
2012 Luo, S.-Y.; Tripathi, A.; Zulueta, M. M. L.; Hung, S.-C., 2-Allylphenyl Glycosides as Glycosyl Donors for Sugar Coupling, Carbohydrate Research, vol. 352, 197-201, 2012
2012 Hsu, Y.; Lu, X.-A.; Zulueta, M. M. L.; Tsai, C.-M.; Lin, K.-I; Hung, S.-C.; Wong, C.-H., Acyl and Silyl Group Effects in Reactivity-based One-pot Glycosylation: Synthesis of Embryonic Stem Cell Surface Carbohydrates Lc4 and IV2Fuc-Lc4, J. Am. Chem. Soc., vol. 134, 4549-4552, 2012
2012 Zulueta, M. M. L.; Lin, S.-Y.; Lin, Y.-T.; Huang, C.-J.; Wang, C.-C.; Ku, C.-C.; Shi, Z.; Chyan, C.-L.; Irene, D.; Lim, L.-H.; Tsai, T.-I; Hu, Y.-P.; Liu, J.-Y.; Chang, W.; Arco, S. D.; Wong, C.-H.; Hung, S.-C., α-Glycosylation by D-Glucosamine-Derived Donors: Synthesis of Heparosan and Heparin Analogs that Interact with Mycobacterial Heparin-Binding Hemagglutinin, J. Am. Chem. Soc., vol. 134(21), 8988-8995, 2012
2012 Hu, Y.-P.; Zhong, Y.-Q.; Chen, Z.-G.; Chen, C.-Y.; Shi, Z.; Zulueta, M. M. L.; Ku, C.-C.; Lee, P.-Y.; Wang, C.-C.; Hung, S.-C., Divergent Synthesis of 48 Heparan Sulfate-Based Disaccharides and Probing the Specific Sugar–Fibroblast Growth Factor-1 Interaction, J. Am. Chem. Soc., vol. 134(51), 20722-20727, 2012
2012 Trees-Juen Chuang)*, Feng-Chi Chen*, Yen-Zho Chen, Position-dependent correlations between the level of DNA methylation and the evolutionary rates of mammalian coding exons, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 109(39), 15841-15846 (impact factor: 9.737; ranking: 4/54: MULTIDISCIPLINARY SCIENCES), 2012
2012 Ming-Chih Wang, Feng-Chi Chen*, Yen-Zho Chen, Yao-Ting Huang, Trees-Juen Chuang*, LDGIdb: a database of gene interactions inferred from long-range strong linkage disequilibrium between pairs of SNPs., BMC Research Note, vol. 5, 212, 2012
2012 Jean-Christophe Gelly, Hsuan-Yu Lin, Alexandre G. de Brevern*, (Trees-Juen Chuang)*, Feng-Chi Chen*, Selective Constraint on Human Pre-mRNA Splicing by Protein Structural Properties, Genome Biology and Evolution, vol. 4(9), 842-851, 2012
2012 Hsu YC, Chen NC, Chen PC, Wang CC, Cheng WC, Wu HN, Identification of a small-molecule inhibitor of dengue virus using a replicon system., Archives of virology, vol. 157(4), 681-688, 2012
2012 Shih HW, Chang YF, Li WJ, Meng FC, Huang CY, Ma C, Cheng TJ, Wong CH, Cheng WC, Effect of the Peptide Moiety of Lipid II on Bacterial Transglycosylase., Angewandte Chemie-International Edition, vol. 51(40), 10123-10126, 2012
2012 Huang CY, Shih HW, Lin LY, Tien YW, Cheng TJ, Cheng WC, Wong CH, Ma C, Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism., Proceedings of the National Academy of Sciences of the United States of America, vol. 109(17), 6496-6501, 2012
2012 Hao-Wei Shih, Kuo-Ting Chen, Wei-Chieh Cheng*, One-pot synthesis of phosphate diesters and phosphonate monoesters via a combination of microwave-CCl3CN-pyridine coupling conditions, Tetrahedron Lett., vol. 53(2), 243-246, 2012