具代表性研究發表

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年度 論文名稱
2015 Cheng PW, Chen YY, Cheng WH, Lu PJ, Chen HH, Chen BR, Yeh TC, Sun GC, (Hsiao M, Tseng CJ, Wnt signaling regulates blood pressure by downregulating a GSK-3beta-mediated pathway to enhance insulin signaling in the central nervous system, Diabetes, vol. Oct;64(10):3413-24. Cite 1, 2015
2015 Chen CW, Lee PH, Chan YC, (Hsiao M)*, Chen CH, Wu PC, Wu PR, Tsai DP, Tu D, Chen X, Liu RS, Plasmon-induced hyperthermia: Hybrid upconversion NaYF4:Yb/Er and gold nanomarterials for oral cancer photothermal therapy, Journal of Materials Chemistry B, vol. 3, 8293-8302. Cite 2, 2015
2015 Chen HH, Lu PJ, Chen BR, (Hsiao M, Ho WY, Tseng CJ, Oxygenase-1 ameliorates kidney ischemia-reperfusion injury of mice by extracellular signal-regulated kinase 1/2-enhanced tubular epithelium proliferation, BiochemicaI et Biophysica Acta-Molecular Basis of Disease, vol. 1852(10 Pt A), 2195-2201, 2015
2015 Hua KT, Chien MH, Lee WJ, Hsieh FK, Li CF, Cheng TY, Wang MY, Chen JS, Chow JM, Jan YH, (Hsiao M, Kuo ML, Keap1-Nrf2 by targeting the S100P protein, Clinical Cancer Research, vol. 21(20), 4719-4732, 2015
2015 Chen JT, Ku KL, Chen CH, (Hsiao M, Chiang CP, Hsu TL, Chen MH, Wong CH., Glycoprotein B7-H3 as a marker for oral cancer: Overexpression and aberrant glycosylation in tumor growth and immune response , Proceedings of the National Academy of Sciences of the United States of America, vol. 112(42), 13057-13062. Cite 1, 2015
2015 Chang TC, Yeh CT, Adebayo BO, Lin YC, Deng L, Rao YK, Huang CC, Lee WH, Wu AT, (Hsiao M, Wu CH, Wang LS, Tzeng YM, 4-Acetylantroquinonol B inhibits colorectal cancer tumorigenesis and suppresses cancer stem-like phenotype, Toxicology and Applied Pharmacology, vol. 288(2), 258-268, 2015
2015 Lin CS, Adebayo BO, Wu A, Chen JH, Peng YJ, Cheng MF, Lee WH, (Hsiao M, Chao TY, Yeh CT, Silencing JARID1B suppresses oncogenicity, stemness and increases radiation sensitivity in human oral carcinoma., Cancer Letters, vol. 368(1), 36-45, 2015
2015 Chang JS, Su CY, Yu WH, WJ Lee, Liu YP, Lai TC, Jan YH, Yang YF, Shen CN, Shew JY, Lu J, Yang CJ, Huang MS, Lu PJ, Lin YF, Kuo ML, Hua KT, (Hsiao M)*, GIT1 promotes lung cancer cell metastasis through modulating Rac1/Cdc42 activity and is associated with poor prognosis, Oncotarget, vol. 6(34), 36278-36291, 2015
2015 Hsiao SM, Chen MW, Chen CA, Chien MH, Hua KT, (Hsiao M, Kuo ML, Wei LH, The H3K9 Methyltransferase G9a represses E-cadherin and is associated with myometrial invasion in endometrial cancer, Annals of Surgical Oncology, vol. Suppl 3, 1556-1565, 2015
2015 C.-C. Tsai, C.-R. Lin, H.-Y. Tsai, C.-J. Chen, W.-T. Li, H.-M. Yu, Y.-Y. Ke, W.-Y. Hsieh, C.-Y. Chang, Y.-T. Wu, S.-T. Chen, C.-H. Wong, The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling, The Journal of biological chemistry, vol. 290(19), 11935, 2015
2015 S. K. C. Cheung, P.-K. Chuang, H.-W. Huang, W. W. Hwang-Verslues, C. H.-H. Cho, W.-B. Yang, C.-N. Shen, M. Hsiao, T.-L. Hsu, C.-F. Chang, C.-H. Wong, Stage-specific embryonic antigen-3 (SSEA-3) and beta3GalT5 are cancer specific and significant markers for breast cancer stem cells, Proceedings of the National Academy of Sciences of the United States of America, vol. 113(4), 960-965, 2015
2015 Y.-Y. Ke, C.-H. Tsai, H.-M. Yu, Y.-C. Jao, J.-M. Fang, C.-H. Wong, Latifolicinin A from a Fermented Soymilk Product and the Structure-Activity Relationship of Synthetic Analogues as Inhibitors of Breast Cancer Cell Growth, Journal of agricultural and food chemistry, vol. 63(44), 9715-9721, 2015
2015 Y.-L. Huang, F.-S. Pai, Y.-T. Tsou, H.-C. Mon, T.-L. Hsu, C.-Y. Wu, T.-Y. Chou, W.-B. Yang, C.-H. Chen, C.-H. Wong, S.-L. Hsieh, Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity, The Journal of biological chemistry, vol. 290(35), 21252-21263, 2015
2015 J.-T. Chen, K.-L. Ku, C.-H. Chen, M. Hsiao, C.-P. Chiang, T.-L. Hsu, M.-H. Chen, C.-H. Wong, Glycoprotein B7-H3 overexpression and aberrant glycosylation in oral cancer and immune response, Proceedings of the National Academy of Sciences of the United States of America, vol. 112(42), 13057-13062, 2015
2015 T.-W. Lin, H.-T. Chang, C.-H. Chen, C.-H. Chen, S.-W. Lin, T.-L. Hsu, C.-H. Wong, Galectin-3 Binding Protein and Galectin-1 Interaction in Breast Cancer Cell Aggregation and Metastasis, Journal of the American Chemical Society, vol. 137(30), 9685-9693, 2015
2015 H.-Y. Yen, Y.-C. Liu, N.-Y. Chen, C.-F. Tsai, Y.-T. Wang, Y.-J. Chen, T.-L. Hsu, P.-C.Yang, C.-H. Wong, Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition, Proceedings of the National Academy of Sciences of the United States of America, vol. 112(22), 6955-6960, 2015
2015 S. Danishefsky, Y.-K. Shue, M. Chang, C.-H. Wong, Development of Globo-H Cancer Vaccine, Accounts of Chemical Research, vol. 48 (3), 643-652, 2015
2015 X. Li, A. Kawamura, C. Andrews, J. Miller, D. Wu; M. Zhang, J. Huang, D. Oren, N. Padte, S. Porcelli, C.-H. Wong, S. Kappe, D. Ho, M. Tsuji, Co-localization of a CD1d-binding glycolipid with malaria vaccines in LN-resident DCs for a robust adjuvant effect, JOURNAL OF IMMUNOLOGY, vol. 195(6), 2710-2721, 2015
2015 C.-H. Wong, Chemistry in Taiwan and Academia Sinica, Angewandte Chemie-International Edition, vol. 54(46), 13472-13473, 2015
2015 C.-W. Lin, M.-H. Tsai, S.-T. Li, T.-I. Tsai, K.-C. Chu, Y.-C. Liu, M.-Y. Lai, C.-Y. Wu, Y.-C. Tseng, S. S. Shivatare, C.-H. Wang, P. Chao, S.-Y. Wang, H.-W. Shih, Y.-F. Zeng, T.-H. You, J.-Y. Liao, Y.-C. Tu, Y.-S. Lin, H.-Y. Chuang, C.-L. Chen, C.-S. Tsai, C.-C. Huang, N.-H. Lin, C. Ma, C.-Y. Wu, C.-H. Wong, A common glycan structure on immunoglobulin G for enhancement of effector functions, Proceedings of the National Academy of Sciences of the United States of America, vol. 112(34), 10611-10616, 2015
2015 Yi-Yu Ke†, Chen-Hsuan Tsai‡, Hui-Ming Yu†, Yu-Chen Jao†, Jim-Min Fang*†‡, Chi-Huey Wong*†, Latifolicinin A from a Fermented Soymilk Product and the Structure–Activity Relationship of Synthetic Analogues as Inhibitors of Breast Cancer Cell Growth, Journal of Agricultural and Food Chemistry, vol. 63(44), 9715-9721, 2015
2015 Tsai CC, Lin CR, Tsai HY, Chen CJ, Li WT, Yu HM, Ke YY, Hsieh WY, Chang CY, Wu YT, Chen ST, Wong CH, The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling, J Biol Chem., vol. 290(19), 11935, 2015
2015 Chein-Hung Chen, Ya-Ping Lin, Jung-Lee Lin, Shiou-Ting Li, Chien-Tai Ren, Chung-Yi Wu, Chung-Hsuan Chen, Rapid Identification of Terminal Sialic Acid Linkage Isomers by Pseudo-MS3 Mass Spectrometry, ISRAEL JOURNAL OF CHEMISTRY, vol. 55(34), 412-422 SI, 2015
2015 Cheung Sarah K. C., Chuang Po-Kai, Huang Han-Wen, Hwang-Verslues Wendy W., Cho Candy Hsin-Hua, Yang Wen-Bin, Shen Chia-Ning, Hsiao Michael, Hsu Tsui-Ling, Chang Chuan-Fa, Wong Chi-Huey, Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells, Proceedings of the National Academy of Sciences, vol. 113(4), 960-965, 2015
2015 Huang YL, Pai FS, Tsou YT, Mon HC, Hsu TL, Wu CY, Chou TY, Yang WB, Chen CH, Wong CH, Hsieh SL, Human CLEC18 gene cluster contains C-type lectins with differential glycan-binding specificity., The Journal of biological chemistry, vol. 290(35), 21252-21263, 2015
2015 Chen JT, Chen CH, Ku KL, Hsiao M, Chiang CP, Hsu TL, Chen MH, Wong CH, Glycoprotein B7-H3 overexpression and aberrant glycosylation in oral cancer and immune response., Proceedings of the National Academy of Sciences of the United States of America, vol. 112(42), 13057-62, 2015
2015 Lin TW, Chang HT, Chen CH, Chen CH, Lin SW, Hsu TL, Wong CH, Galectin-3 binding protein and galactin-1 interaction in breast cancer cell aggregation and metastasis., Journal of the American Chemical Society, vol. 137(30), 9685-9693, 2015
2015 Yen Hsin-Yung, Liu Ying-Chih, Chen Nai-Yu, Tsai Chia-Feng, Wang Yi-Ting, Chen Yu-Ju, Hsu Tsui-Ling, Yang Pan-Chyr, Wong Chi-Huey, Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition, Proceedings of the National Academy of Sciences, vol. 112(22), 6955-6960, 2015
2015 Patil PS, (Cheng TJ, Zulueta MM, Yang ST, Lico LS, Hung SC*, Total synthesis of tetraacylated phosphatidylinositol hexamannoside and evaluation of its immunomodulatory activity., Nature communications, vol. 6, 7239-7247, 2015
2015 Lin MI, Su BH, Lee CH, Wang ST, Wu WC, Dangate P, Wang SY, Huang WI, (Cheng TJ, Lin OA, Cheng YS, * Tseng YJ, * Sun CM*, Synthesis and inhibitory effects of novel pyrimido-pyrrolo-quinoxalinedione analogues targeting nucleoproteins of influenza A virus H1N1., European journal of medicinal chemistry, vol. 102, 477-486, 2015