具代表性研究發表

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年度 論文名稱
2021 Shivatare SS, Cheng TR, Cheng YY, Shivatare VS, Tsai TI, Chuang HY, Wu CY, Wong CH*, Immunogenicity Evaluation of N-Glycans Recognized by HIV Broadly Neutralizing Antibodies., ACS chemical biology, vol. 16(10), 2016-2025, 2021
2021 Jan JT, (Cheng TR, Juang YP, Ma HH, Wu YT, Yang WB, Cheng CW, Chen X, Chou TH, Shie JJ, Cheng WC, Chein RJ, Mao SS, Liang PH, Ma C, Hung SC, Wong CH, Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection., Proceedings of the National Academy of Sciences of the United States of America, vol. 118(5), e2021579112, 2021
2021 Ko YA, Yu YH, Wu YF, Tseng YC, Chen CL, Goh KS, Liao HY, Chen TH, (Cheng TR, Yang AS, Wong CH, Ma C, Lin KI, A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells., PLoS pathogens, vol. 17(8), e1009724, 2021
2021 Lin MH, Cho CC, Chiu YC, Chien CY, Huang YP, (Chang CF, Hsu CH, Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites., Communications biology, vol. 4(1), 123, 2021
2021 Maksimov EG, Laptev GY, Blokhin DS, Klochkov VV, Slonimskiy YB, Sluchanko NN, Friedrich T, (Chang CF, Polshakov VI, NMR resonance assignment and backbone dynamics of a C-terminal domain homolog of orange carotenoid protein., Biomolecular NMR assignments, vol. 15(1), 17-23, 2021
2021 Lin MH, Huang YP, (Chang CF)*, Hsu CH*, NMR assignments of the macro domain from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)., Biomolecular NMR assignments, vol. 15(1), 137-142, 2021
2021 Li Hao-Kai, (Chang Chi-Fon, Lin Hsuan-Ju, Lin Jung-Lee, Lee Yu-Ting, Wu Yu-Hsuan, Liu Chiao-Yen, Lin Tze-Chia, Hsu Pang-Hung, Lin Hong-Ting Victor, Conversion of a Thiol Precursor into Aroma Compound 4-mercapto-4-methyl-2-pentanone Using Microbial Cell Extracts, Fermentation, vol. 7(3), 129, 2021
2021 Liu Z, Derkach A, Yu KJ, Yeager M, Chang YS, Chen CJ, Gyllensten U, Lan Q, Lee MH, McKay JD, Rothman N, Yang HI, Hildesheim A, Pfeiffer RM, Patterns of Human Leukocyte Antigen Class I and Class II Associations and Cancer., Cancer Research, vol. 81(4), 1148-1152, 2021
2021 Liu Matt, Tseng Tai-Chung, Jun Dae Won, Yeh Ming-Lun, Trinh Huy, Wong Grace L. H., Chen Chien-Hung, Peng Cheng-Yuan, Kim Sung Eun, Oh Hyunwoo, Kwak Min-Sun, Cheung Michael, Toyoda Hidenori, Hsu Yao-Chun, Jeong Jae Yoon, Yoon Eileen L., Ungtrakul Teerapat, Zhang Jian, Xie Qing, Ahn Sang Bong, Enomoto Masaru, Shim Jae-Jun, Cunningham Chris, Jeong Soung Won, Cho Yong Kyun, Ogawa Eiichi, Huang Rui, Lee Dong-Hyun, Takahashi Hirokazu, Tsai Pei-Chien, Huang Chung-Feng, Dai Chia-Yen, Tseng Cheng-Hao, Yasuda Satoshi, Kozuka Ritsuzo, Li Jiayi, Wong Christopher, Wong Clifford C., Zhao Changqing, Hoang Joseph, Eguchi Yuichiro, Wu Chao, Tanaka Yasuhito, Gane Ed, Tanwandee Tawesak, Cheung Ramsey, Yuen Man-Fung, Lee Hyo-Suk, Yu Ming-Lung, Kao Jia-Horng, (Yang Hwai-I, Nguyen Mindie H., Transition rates to cirrhosis and liver cancer by age, gender, disease and treatment status in Asian chronic hepatitis B patients, Hepatology International, vol. 15(1), 71-81, 2021
2021 Polaris Observatory Collaborators, The case for simplifying and using absolute targets for viral hepatitis elimination goals., JOURNAL OF VIRAL HEPATITIS, vol. 28(1), 12-19, 2021
2021 Tsai TY, Huang MT, Sung PS, Peng CY, Tao MH, (Yang HI, Chang WC, Yang AS, Yu CM, Lin YP, Bau CY, Huang CJ, Pan MH, Wu CY, Hsiao CD, Yeh YH, Duan S, Paulson JC, Hsieh SL, SIGLEC-3 (CD33) serves as an immune checkpoint receptor for HBV infection., The Journal of clinical investigation, vol. 131(11), e141965, 2021
2021 Teng W, Chang TT, (Yang HI, Peng CY, Su CW, Su TH, Hu TH, Yu ML, Yang HC, Wu JC, Risk scores to predict HCC and the benefits of antiviral therapy for CHB patients in gray zone of treatment guidelines., Hepatology international, vol. 15(6), 1421-1430, 2021
2021 Wu HC, (Yang HI, Lin PH, Chen CJ, Santella RM, Terry MB, Reproductive and environmental exposures and the breast cancer risk in Taiwanese women., Scientific reports, vol. 11(1), 15656, 2021
2021 Chung CW, Hsiao TH, Huang CJ, Chen YJ, Chen HH, Lin CH, Chou SC, Chen TS, Chung YF, (Yang HI, Chen YM, Machine learning approaches for the genomic prediction of rheumatoid arthritis and systemic lupus erythematosus., BioData mining, vol. 14(1), 52, 2021
2021 Koshiol J, Argirion I, Liu Z, Kim Lam T, O'Brien TR, Yu K, McGlynn KA, Petrick JL, Pinto L, Chen CJ, Hildesheim A, Pfeiffer RM, Lee MH, (Yang HI, Immunologic markers and risk of hepatocellular carcinoma in hepatitis B virus- and hepatitis C virus-infected individuals., Alimentary pharmacology & therapeutics, vol. 54(6), 833-842, 2021
2021 Liu Z, Huang CJ, Huang YH, Pan MH, Lee MH, Yu KJ, Pfeiffer RM, Viard M, Yuki Y, Gao X, Carrington M, Chen CJ*, Hildesheim A*, (Yang HI*, HLA zygosity increases risk of hepatitis B virus-associated hepatocellular carcinoma., JOURNAL OF INFECTIOUS DISEASES, vol. 224(10), 1796-1805, 2021
2021 Wu S, Zeng N, Sun F, Zhou J, Wu X, Sun Y, Wang B, Zhan S, Kong Y, Jia J, You H*, (Yang HI*, Hepatocellular Carcinoma Prediction Models in Chronic Hepatitis B: A Systematic Review of 14 Models and External Validation., CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, vol. 19(12), 2499-2513, 2021
2021 Wang Z, Budhu AS, Shen Y, Wong LL, Hernandez BY, Tiirikainen M, Ma X, Irwin ML, Lu L, Zhao H, Lim JK, Taddei T, Mishra L, Pawlish K, Stroup A, Brown R, Nguyen MH, Koshiol J, Hernandez MO, Forgues M, (Yang HI, Lee MH, Huang YH, Iwasaki M, Goto A, Suzuki S, Matsuda K, Tanikawa C, Kamatani Y, Mann D, Guarnera M, Shetty K, Thomas CE, Yuan JM, Khor CC, Koh WP, Risch H, Wang XW, Yu H, Genetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome-wide association study., JGH open, vol. 5(12), 1363-1372, 2021
2021 Chen Chien-Jen, You San-Lin, Hsu Wan-Lun, (Yang Hwai-I, Lee Mei-Hsuan, Chen Hui-Chi, Chen Yun-Yuan, Liu Jessica, Hu Hui-Han, Lin Yu-Ju, Chu Yu-Ju, Huang Yen-Tsung, Chiang Chun-Ju, Chien Yin-Chu, Epidemiology of Virus Infection and Human Cancer, Recent Results Cancer Res, vol. 217, 13-45, 2021
2021 Yang HI*, Hsu YC, Editorial: incorporating liver stiffness to risk scores for HCC in patients with chronic hepatitis B treated with oral antivirals: ready to use or not?, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, vol. 53(6), 753-754, 2021
2021 Le AK, (Yang HI, Yeh ML, Jin M, Trinh HN, Henry L, Liu A, Zhang JQ, Li J, Wong C, Wong C, Cheung R, Yu ML, Nguyen MH, Development and validation of a risk score for liver cirrhosis prediction in untreated and treated chronic hepatitis B., JOURNAL OF INFECTIOUS DISEASES, vol. 223(1), 139-146, 2021
2021 Pan WC*, Yeh SY, Wu CD, Huang YT, Chen YC, Chen CJ, (Yang HI*, Association between Traffic Count and Cardiovascular Mortality: A Prospective Cohort Study in Taiwan., JOURNAL OF EPIDEMIOLOGY, vol. 31(5), 343-349, 2021
2021 Argirion I, Pfeiffer RM, Lam TK, O'Brien TR, Yu K, McGlynn KA, Petrick JL, Pinto L, Chen CJ, Lee MH, Hildesheim A, (Yang HI, Koshiol J, Association between immunologic markers and cirrhosis in individuals with chronic hepatitis B., Scientific reports, vol. 11(1), 21194, 2021
2021 Li Jie, (Yang Hwai-I, Yeh Ming-Lun, Le Michael H, Le An K, Yeo Yee Hui, Dai Chia-Yen, Barnett Scott, Zhang Jian Q, Huang Jee-Fu, Trinh Huy N, Wong Christopher, Wong Clifford, Hoang Joseph K, Cheung Ramsey, Yu Ming-Lung, Nguyen Mindie H, Association between fatty liver and cirrhosis, hepatocellular carcinoma, and HBsAg seroclearance in chronic hepatitis B, The Journal of Infectious Diseases, vol. 224 (2) , 294-302, 2021
2021 Hsu YC, Tseng CH, Huang YT, (Yang HI, Application of Risk Scores for Hepatocellular Carcinoma in Patients with Chronic Hepatitis B: Current Status and Future Perspective., SEMINARS IN LIVER DISEASE, vol. 41(3), 285-297, 2021
2021 Wei SC, Hsu WT, Chiu CH, Chang FY, Lo HR, Liao CY, (Yang HI, Chou YC, Tsai CH, Chao YC, An Integrated Platform for Serological Detection and Vaccination of COVID-19., FRONTIERS IN IMMUNOLOGY, vol. 12, 771011, 2021
2021 Liu PC, Chan C, Huang YH, Chen YJ, Liao SF, Lin YJ, Huang C, Lu SN, Jen CL, Wang LY, (Yang HI, Shen CY, Chen CJ, Lee MH, Genetic variants associated with serum alanine aminotransferase levels among patients with hepatitis C virus infection: A genome-wide association study., Journal of viral hepatitis, 2021
2021 Wu, H.H., L.H. Tsai, C.K. Huang, S.C. Huang, P.H. Hsu, M.Y. Chen, Y.I. Chen, C.M. Hu, (C.N.Shen, C.C. Lee, M.C. Chang, Y.T. Chang, Y.W. Tien, Y.M. Jeng, E. Lee, W.H. Lee*, Characterization of initial key steps of IL-17 receptor B oncogenic signaling for targeted therapy of pancreatic cancer, Science Translational Medicine, vol. 13, eabc2823, 2021
2021 Hsu HJ, Tung CP, Yu CM, Chen CY, Chen HS, Huang YC, Tsai PH, Lin SI, Peng HP, Chiu YK, Tsou YL, Kuo WY, Jian JW, Hung FH, Hsieh CY, Hsiao M, Chuang SS, (Shen CN, Wang YA, Yang AS, Eradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody-drug conjugates from synthetic antibody libraries., Scientific reports, vol. 11(1), 15430, 2021
2021 Hsu, L.J., C.L. Liu, M.L.Kuo, (C.N. Shen, C.R.Shen*, An Alternative Cell Therapy for Cancers: Induced Pluripotent Stem Cell (iPSC)-Derived Natural Killer Cells, Biomedicines, vol. 9, 1323, 2021