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-C-Modified Heparan Sulfate Trisaccharides as Human Endo-6-O-Sulfatase 1 Inhibitors., Frontiers in Chemistry, vol. 10, 947475, 2022
年度 論文名稱
2022 Wu, J.-L., Wu, H.-Y., Wu, S.-J., Tsai, H.-Y., Weng, S.-H., Lin, K.-T., Lin, L.-I., Yao, C.-Y., Zamanova, M., Lee, Y.-Y., Angata, T., Tien, H.-F., Chen, Y.-J.*, Lin, K.-I*, Phosphoproteomics reveals the role of constitutive KAP1 phosphorylation by B-cell receptor signaling in chronic lymphocytic leukemia, Molecular Cancer Research, vol. https://doi.org/10.1158/1541-7786., MCR-21-0722, 2022
2022 M. H. Chen, Y. S. Li, N. S. Hsu, K. H. Lin, Y. L. Wang, Z. C. Wang, C. F. Chang, J. P. Lin, C. Y. Chang, T. L. Li*, Structural and mechanistic bases for StnK3 and its mutants-mediated Lewis-acid-dependent epimerization and retro aldol reactions, ACS CATALYSIS, vol. 12, 1945-1956, 2022
2022 R. Rattinam, R. S. Basha, Y. L. Wang, Z. C. Wang, N. S. Hsu, K. H. Lin, S. Malek Zadeh, K. Adhikari, J. P. Lin, T. L. Li*, KasQ an epimerase primes the biosynthesis of aminoglycoside antibiotic kasugamycin and KasF/H acetyltransferases inactivate its activity, BIOMEDICINES, vol. 10(2), 212, 2022
2022 B. R. Chen, W. M. Li, T. L. Li, Y. L. Chan, C. J. Wu*, Fucoidan from Sargassum hemiphyllum inhibits infection and inflammation of Helicobacter pylori, SCIENTIFIC REPORTS, vol. 12(1), 429, 2022
2022 Y. C. Pan, Y. L. Wang, S. I. Toh, N. S. Hsu, K. H. Lin, Z. Xu, S. C. Huang, T. K. Wu, T. L. Li, C. Y. Chang*, Dual-mechanism confers self-resistance to the antituberculosis antibiotic capreomycin, ACS CHEMICAL BIOLOGY, vol. 17(1), 138-146, 2022
2022 C. C. Liaw, I. W. Lo, Y. C. Lin, H. T. Huang, L. J. Zhang, P. C. Hsiao, T. L. Li, * Y. H. Kuo*, Four cucurbitane glycosides taimordisins A–D with novel furopyranone skeletons isolated from the fruits of Momordica charantia, FOOD CHEMISTRY: X, vol. 14, 100286, 2022
2022 S. M. Zadeh, M. H. Chen, Z. C. Wang, E. K. Astani, I. W. Lo, K. H. Lin, N. S. Hsu, K. Adhikari, S. Y. Lyu, H. Y. Tsai, Y. Terasawa, M. Yabe, K. Yamamoto, S. Ichikawa, T. L. Li*, β-Hydroxylation of α-amino-β-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin, COMMUNICATIONS CHEMISTRY, vol. 5, 87, 1-16, 2022
2022 E. Astani, S. M. Zadeh, N. S. Hsu, K. H. Lin, S. Sardari, T. L. Li*, Intermolecular Interactions of Nucleoside Antibiotic Tunicamycin with On-Target MraYcb-TUN and Off-Target DPAGT1-TUN in the Active Sites Delineated by Quantum Mechanics/Molecular Mechanics Calculations, ACS OMEGA, vol. 7(37), 32970-32987, 2022
2022 Z. C. Wang, I. W. Lo, K. H. Lin, A. N. Cheng, S. M. Zadeh, Y. H. Huang, T. L. Li*, Genetic and biochemical characterization of halogenation and drug-transportation genes encoded in the albofungin biosynthetic gene cluster, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 88(17):e0080622, 1-20, 2022
2022 I. W. Lo, G. Y. Liao, J. C. Lee, C. I. Chang, Y. C. Wu, S. P. Liu, H. J. Su, C. I. Liu, C. Y. Kuo, Z.Y. Lin, T. L. Li*, Y. S. Lin*, C. C. Liaw*, Novel Aporphine- and Proaporphine-Clerodane Hybrids Identified from the Barks of Taiwanese Polyalthia Longifolia var. pendula with Strong Anti-DENV2 Activity, PHARMACEUTICS, vol. 15(10), 1218, 1-15, 2022
2022 H. T. Huang, I. W. Lo, G. Y. Liao, Y. C. Lin, Y. C. Shen, H. C. Huang, T. L. Li, K. T. Lee, Y. H. Kuo*, C. C. Liaw*, Anti-inflammatory sesquiterpene and triterpene acids from Mesona procumbens Hemsley, FRONTIERS IN CHEMISTRY, vol. 10:1003356, 1-13, 2022
2022 Hsu YS, Wu PJ, Jeng YM, Hu CM*, Lee WH*., Differential Effects of Glucose and N-acetylglucosamine on Genome instability., Am J Cancer Res, vol. 12, 1556-1567, 2022
2022 Chen YI, Chang CC, Hsu MF, Jeng YM, Tien YW, Chang MC, Chang YT, Hu CM*, Lee WH*, Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation., Nature communications, vol. 13, 2945, 2022
2022 Liu Yu-Huei, Hu Chun-Mei, Hsu Yuan-Sheng, Lee Wen-Hwa, Interplays of glucose metabolism and KRAS mutation in pancreatic ductal adenocarcinoma, Cell Death & Disease, vol. 13(9), 817-826, 2022
2022 Lee Wen-Hsin, Chen Xiaorui, Liu I-Ju, Lee Jiin-Horng, Hu Chun-Mei, Wu Han-Chung, Wang Sheng-Kai, Lee Wen-Hwa, Ma Che, Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation, Cell Reports, vol. 41(4), 111555, 2022
2022 Chen Jia-Yang, Chou Hsu-Huan, Lim Syer Choon, Huang Yen-Jang, Lai Kuan-Chen, Guo Chin-Lin, Tung Chien-Yi, Su Chung-Tsai, Wang Jocelyn, Liu Edward, Han Hsiao-Fen, Yeh Po-Ying, Hu Chun-Mei, Dunn Alexander R., Frank Curtis W., Wu Yi-Chun, Yang Muh-Hwa, Chang Ying-Chih, Multiomic characterization and drug testing establish circulating tumor cells as an ex vivo tool for personalized medicine, iScience, vol. 25(10), 105081, 2022
2022 Weng WC, Liao HE, Huang SP, Tsai ST, Hsu HC, Liew CY, Gannedi V, Hung SC, Ni CK, Unusual free oligosaccharides in human bovine and caprine milk., Scientific Reports, vol. 12(1), 10790, 2022
2022 Liew CY, Hsu HC, Nguan HS, Huang YC, Zhong YQ, Hung SC, Ni CK, The Good, the Bad, and the Ugly Memories of Carbohydrate Fragments in Collision-Induced Dissociation., Journal of the American Society for Mass Spectrometry, vol. 33(10), 1891-1903, 2022
2022 Wang Chih-Hung, Chang Jia-Ru, Hung Shang-Cheng, Dou Horng-Yunn, Lee Gwo-Bin, Rapid molecular diagnosis of live Mycobacterium tuberculosis on an integrated microfluidic system, Sensors and Actuators B: Chemical, vol. 12(1), 10790, 2022
2022 Tseng KY, Tzeng ZH, Cheng TR, Liang PH, Hung SC, Design and Synthesis of 1-O- and 6
2022 Byung-sun Jeon, Teng-Yi Huang, Mark W. Ruszczycky, Sei-hyun Choi, Namho Kim, Joseph Livy Franklin, (Shang-Cheng Hung*, Hung-wen Liu*, Byproduct formation during the biosynthesis of spinosyn A and evidence for an enzymatic interplay to prevent its formation, TETRAHEDRON, vol. 103, 132569, 2022
2022 Teng KC, Tseng KY, Tzeng ZH, Hung SC, A concise synthesis of L-gulose and its C-6 derivatives., Bioorganic & Medicinal Chemistry, vol. 73, 117029, 2022
2022 Lu Tsung-Han, Chiang Nai-Jung, Tsai Yi-Cheng, Gopinathan Priya, Huang Chien-Jui, Chang Jui-Lin, Tu Hsiu-Chi, Shan Yan-Shen, Hung Shang-Cheng, Lee Gwo-Bin, An integrated microfluidic system for cholangiocarcinoma diagnosis from bile by using specific affinity probes, Sensors and Actuators B: Chemical, vol. 373, 132724, 2022
2022 Uchimura K, Nishitsuji K, Chiu LT, Ohgita T, Saito H, Allain F, Gannedi V, Wong CH, Hung SC, Design and Synthesis of 6-O-Phosphorylated Heparan Sulfate Oligosaccharides to Inhibit Amyloid beta Aggregation., Chembiochem : a European journal of chemical biology, vol. 23(15), e202200191, 2022
2022 Tai‑Wei Chiang, Te‑Lun Mai, Trees‑Juen Chuang*, CircMiMi: a stand‑alone software for constructing circular RNA‑microRNA‑mRNA interactions across species, BMC Bioinformatics, vol. 23, 164, 2022
2022 Te-Lun Mai, Chia-Ying Chen, Yu-Chen Chen, Tai-Wei Chiang, Trees-Juen Chuang*, Trans-genetic effects of circular RNA expression quantitative trait loci and potential causal mechanisms in autism, MOLECULAR PSYCHIATRY, vol. 27, 4695-4706 (SCI impact factor: 9.6; Rank (PSYCHIATRY): 6/276), 2022
2022 Lee Hua-Yun, Chiang Po-Yu, Wu Hsi-Ju, Wang Ting-Yi, Yang Tzu-Ching, Cheng Wei-Chieh, Lo Lee-Chiang, Liao Wei-Ssu, Versatile Azido-Functionalized Carbon Dots for Cancer Cell Imaging, ACS Applied Nano Materials, vol. 5(9), 12374-12379, 2022
2022 Chen WA, Li HY, Sayyad A, Huang CY, Cheng WC, Synthesis of Nitrone-derived Pyrrolidine Scaffolds and Their Combinatorial Libraries to Develop Selective alpha-l-Rhamnosidase Inhibitors., Chemistry, an Asian journal, vol. 17(14), e202200172, 2022
2022 Guo CW, Chen KT, You TY, Lin CC, Cheng WC, Synthesis and Evaluation of Diverse N-Substituted Disaccharide Dipeptides for Human NOD2 Stimulation Activity., Chemistry, an Asian journal, vol. 17(4), e202101169, 2022
2022 Chen Wei-An, Chen Yu-Hsin, Hsieh Chiao-Yun, Hung Pi-Fang, Chen Chiao-Wen, Chen Chien-Hung, Lin Jung-Lee, Cheng Ting-Jen R., Hsu Tsui-Ling, Wu Ying-Ta, Shen Chia-Ning, Cheng Wei-Chieh, Harnessing natural-product-inspired combinatorial chemistry and computation-guided synthesis to develop N-glycan modulators as anticancer agents, Chemical Science, vol. 13, 6233-6243, 2022