具代表性研究發表

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年度 論文名稱
2022 Cheung EC, Vousden KH, The role of ROS in tumour development and progression., Nature reviews. Cancer, vol. 22(5), 280-297, 2022
2022 D'Avola A, Legrave N, Tajan M, Chakravarty P, Shearer RL, King HW, Kluckova K, Cheung EC, Clear AJ, Gunawan AS, Zhang L, James LK, MacRae JI, Gribben JG, Calado DP, Vousden KH, Riches JC, PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma., The Journal of clinical investigation, vol. 132(9), e153436, 2022
2022 Chien Hsiu-Wen, Wu Jen-Chia, (Chang Ying-Chih)*, Tsai Wei-Bor*, Polycarboxybetaine-Based Hydrogels for the Capture and Release of Circulating Tumor Cells, Gels, vol. 8(7), 391, 2022
2022 Chen Jia-Yang, Chou Hsu-Huan, Lim Syer Choon, Huang Yen-Jang, Lai Kuan-Chen, Guo Chin-Lin, Tung Chien-Yi, Su Chung-Tsai, Wang Jocelyn, Liu Edward, Han Hsiao-Fen, Yeh Po-Ying, Hu Chun-Mei, Dunn Alexander R., Frank Curtis W., Wu Yi-Chun*, Yang Muh-Hwa*, (Chang Ying-Chih)*, Multiomic characterization and drug testing establish circulating tumor cells as an ex vivo tool for personalized medicine, iScience, vol. 25(10), 105081, 2022
2022 Huang CY, Nicholson MW, Wang JY, Ting CY, Tsai MH, Cheng YC, Liu CL, Chan DZH, Lee YC, Hsu CC, Hsu YH, Yang CF, Chang CMC, Ruan SC, Lin PJ, Lin JH, Chen LL, Hsieh ML, Cheng YY, Hsu WT, Lin YL, Chen CH, Hsu YH, (Wu YT, Hacker TA, Wu JC, Kamp TJ, Hsieh PCH, Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons, CELL REPORTS, vol. 39(1), 110643, 2022
2022 Chen WA, Chen YH, Hsieh CY, Hung PF, Chen CW, Chen CH, Lin JL, Cheng TR, Hsu TL, (Wu YT, Shen CN, Cheng WC, Harnessing natural-product-inspired combinatorial chemistry and computation-guided synthesis to develop N-glycan modulators as anticancer agents, CHEMICAL SCIENCE, vol. 13(21), 6233-6243, 2022
2022 Nicholson MW, Huang CY, Wang JY, Ting CY, Cheng YC, Chan DZH, Lee YC, Hsu CC, Hsu YH, Chang CMC, Hsieh ML, Cheng YY, Lin YL, Chen CH, (Wu YT, Hacker TA, Wu JC, Kamp TJ, Hsieh PCH, Cardio- and Neurotoxicity of Selected Anti-COVID-19 Drugs, PHARMACEUTICALS, vol. 15(6), 765, 2022
2022 Chuang HC, Liu MF, Wu HY, Cheng TR, Fang JM, Photoaffinity labeling of benzophenone-containing salicylanilide compounds to give an insight into the mechanism in disrupting peptidoglycan formation, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 67, 116819, 2022
2022 Chen Chiang-Yun, Lin Yu-Wei, Wang Szu-Wen, Lin Yung-Chu, Cheng Yang-Yu, (Ren Chien-Tai, Wong Chi-Huey, Wu Chung-Yi*, Synthesis of Azido-Globo H Analogs for Immunogenicity Evaluation, ACS Central Science, vol. 8(1), 77-85, 2022
2022 Lin Tzu-Lung, Yang Feng-Ling, (Ren Chien-Tai, Pan Yi-Jiun, Liao Kuo-Shiang, Tu I-Fan, Chang Yu-Pei, Cheng Yang-Yu, Wu Chung-Yi*, Wu Shih-Hsiung*, Wang Jin-Town*, Development of Klebsiella pneumoniae Capsule Polysaccharide-Conjugated Vaccine Candidates Using Phage Depolymerases, Frontiers in Immunology, vol. 13, 843183, 1-13, 2022
2022 Wu NL, Huang DY, (Hsieh SL, Dai YS, Lin WW, Decoy receptor 3 is involved in epidermal keratinocyte commitment to terminal differentiation via EGFR and PKC activation., Experimental & molecular medicine, vol. 54(4), 542-551, 2022
2022 Wu YH, Mo ST, Chen IT, Hsieh FY, (Hsieh SL, Zhang J, Lai MZ, Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells., Science advances, vol. 8(45), eabn9912, 2022
2022 Hsu YW, Huang H CH, Huang WC, Yeh YH, Hsiao CD, Chang WC**, (Hsieh SL)**, Human rs75776403 Polymorphism Links Differential Phenotypic and Clinical Outcomes to a CLEC18A p.T151M-Driven Multiomics, JOURNAL OF BIOMEDICAL SCIENCE, vol. 29(1), 43, 2022
2022 Weng SC, Wen MC, (Hsieh SL, Chen NJ, Tarng DC*, Decoy Receptor 3 Suppresses T-Cell Priming and Promotes Apoptosis of Effector T-Cells in Acute Cell-Mediated Rejection: The Role of Reverse Signaling, FRONTIERS IN IMMUNOLOGY, vol. 13, 879648, 2022
2022 Sung PS, Yang SP, Perng YC, Sun CP, Tao MH, (Hsieh SL)*, CLEC5A and TLR2 are critical in SARS-CoV-2-induced NET formation and lung inflammation, JOURNAL OF BIOMEDICAL SCIENCE, vol. 29(1), 52, 2022
2022 Sung PS, Peng YC, Yang SP, Chiu CH, (Hsieh SL)*, CLEC5A is critical in Pseudomonas aeruginosa-induced NET formation and acute lung injury, JCI INSIGHT, vol. 7(18), e156613, 2022
2022 Lin EH, Hsu JW, Lee TF, Hsu CF, Lin TH, Jan YH, Chang HY, Cheng CM, Hsu HJ, Chen WW, Chen BH, Tsai HF, Li JJ, Huang CY, Chuang SH, Chang JM, (Hsiao M, Wu CW, Targeting cancer stemness mediated by BMI1 and MCL1 for non-small cell lung cancer treatment., JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, vol. 26(15), 4305-4321, 2022
2022 Li Chien-Hsiu, Chan Ming-Hsien, Liang Shu-Mei, Chang Yu-Chan, (Hsiao Michael, Fascin-1: Updated biological functions and therapeutic implications in cancer biology, BBA Advances, vol. 2, 100052, 2022
2022 Tsai MT, Sun YS, Keerthi M, Panda AK, Dhawan U, Chang YH, Lai CF, (Hsiao M, Wang HY, Chung RJ, Oral Cancer Theranostic Application of FeAu Bimetallic Nanoparticles Conjugated with MMP-1 Antibody, NANOMATERIALS, vol. 12(1), 61, 2022
2022 Chang ZX, Li CH, Chang YC, Huang CYF, Chan MH, (Hsiao M)*, Novel Monodisperse FePt Nanocomposites for T2-weighted Magnetic Resonance Imaging: Biomedical Theranostics Applications [COVER STORY], NANOSCALE ADVANCES, vol. Jan 21;4(2), 377-386, 2022
2022 Chou CC, Hua KT, Chen MW, Wu CJ, Hsu CH, Wang JT, (Hsiao M, Wei LH, Discovery and Characterization of A Monoclonal Antibody Targeting A Conformational Epitope of IL-6/IL-6Rα to Inhibit IL-6/ IL-6Rα/gp130 Hexameric Signaling Complex Formation, MABS, vol. 14(1), 2029675, 2022
2022 Chang YC, Chang PM, Li CH, Chan MH, Lee YJ, Chen MH, (Hsiao M)*, Aldolase A and Phospholipase D1 Synergistically Resist Alkylating Agents and Radiation in Lung Cancer., FRONTIERS IN ONCOLOGY, vol. Jan 21;11, 811635, 2022
2022 Chan MH, Huang WT, Satpathy A, Su TY, (Hsiao M)*, Liu RS, Progress and Viewpoints of Multifunctional Composite Nanomaterials for Glioblastoma Theranostics, PHARMACEUTICS, vol. Feb 21;(14), 459, 2022
2022 Li LJ, Chang PM, Li CH, Lai TC, Chang YC, Su CY, Chen CL, Chang WM, (Hsiao M)*, Fung SW, FAS Receptor Regulates NOTCH Activity through ERK-JAG1 Axis Activation and Controls Oral Cancer Stemness Ability and Pulmonary Metastasis, CELL DEATH DISCOVERY, vol. In Press, 1, 2022
2022 Chuang HH, Zhen YY, Tsai YC, Chuang CH, (Hsiao M, Huang MS, Yang CJ, FAK in Cancer: From Mechanisms to Therapeutic Strategies, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. Feb 2;23(3), 1726, 2022
2022 Wen YC, Chen WY, Tram VTN, Yeh HL, Chen WH, Jiang KC, Abou-Kheir W, Huang J, (Hsiao M, Liu YN, Pyruvate Kinase L/R Links Metabolism Dysfunction to Neuroendocrine Differentiation of Prostate Cancer by ZBTB10 Deficiency, CELL DEATH & DISEASE, vol. 13(3), 252, 2022
2022 Wen YC, Liu CL, Yeh HL, Chen WH, Jiang KC, Tram VTN, (Hsiao M, Huang J, Chen WY, Liu YN, PCK1 Regulates Neuroendocrine Differentiation in A Positive Feedback Loop of LIF/ZBTB46 Signalling in Castration-resistant Prostate Cancer, BRITISH JOURNAL OF CANCER, vol. 126(5), 778-790, 2022
2022 Tung MC, Lin YW, Lee WeJ, Wen YC, Liu YC, Chen JQ, (Hsiao M, Yang YC, Chien MH, Targeting DRD2 by the Antipsychotic Drug, Penfluridol, Retards Growth of Renal Cell Carcinoma via Inducing Stemness Inhibition and Autophagy-mediated Apoptosis, CELL DEATH & DISEASE, vol. Apr23;13(4), 400, 2022
2022 Chang YC, Li C, Chan MH, Chen MH, Yeh CN, (Hsiao M)*, Regorafenib Inhibits Epithelial-mesenchymal Transition and Suppresses Cholangiocarcinoma Metastasis via YAP1-AREG Axis, CELL DEATH & DISEASE, vol. 13(4), 391, 2022
2022 Chan MH, Chang ZX, Huang CYF, Lee LJ, Liu RS, (Hsiao M)*, Integrated Therapy Platform of Exosomal System: Hybrid Inorganic/Organic Nanoparticles with Exosomes for Cancer Treatment [COVER STORY], NANOSCALE HORIZONS, vol. 7(4), 352-367, 2022