具代表性研究發表

搜尋類別: 關鍵字搜尋: Clear
年度 論文名稱
2012 T. L. Lin, F. L. Yang, A. S. Yang, H. P. Peng, T. L. Li, M. D. Tsai, S. H. Wu, J. T. Wang*, Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharide, PLOS ONE, vol. 7(10), e46783, 2012
2012 Hsu CH, Peng KL, Jhang HC, Lin CH, Wu SY, Chiang CM, Lee SC, Yu WC, (Juan LJ)*, The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription., Oncogene, vol. 31(18), 2335-49, 2012
2012 Hsu CH, Peng KL, Kang ML, Chen YR, Yang YC, Tsai CH, Chu CS, Jeng YM, Chen YT, Lin FM, Huang HD, Lu YY, Teng YC, Lin ST, Lin RK, Tang FM, Lee SB, Hsu HM, Yu JC*, Hsiao PW*, (Juan LJ)*, TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases., Cell reports, vol. 2(3), 568-79, 2012
2012 Hwang-Verslues, W.W.)*, Lee, W.-H., Lee, E.Y.-H.P., Biomarkers to target heterogeneous breast cancer stem cells (invited review), Journal of Molecular Biomarkers & Diagnosis, vol. S8, 006, 2012
2012 Chang, P.-H., (Hwang-Verslues, W.W., Chang, Y.-C., Chen, C.-C., Hsiao, M., Jeng, Y.-M., Chang, K.-J., Lee, E. Y.-H. P., Shew, J.-Y., Lee, W.-H., Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway, CANCER RESEARCH, vol. 72(18), 4652-4661, 2012
2012 Hu CM, Yeh MT, Tsao N, Chen CW, Gao QZ, Chang CY, Lee MH, Fang JM, Sheu SY, Lin CJ, Tseng MC, Chen YJ, Chang ZF, Tumor cells require thymidylate kinase to prevent dUTP incorporation during DNA repair., CANCER CELL, vol. 22, 36-50, 2012
2012 Hung, S.-C.; Lu, X.-A.; Lee, J.-C.; Fang, S.-L.; Fan, T.-C.; Chang, M. D.-T.; Zulueta, M. M. L.; Chiu, L.-T., Synthesis of Heparin Oligosaccharides and Their Interaction with Eosinophil-Derived Neurotoxin, Org. Biomol. Chem., vol. 10, 760-772, 2012
2012 Hsu, C.-Y.; Lee, I-C.; Lico, L. S.; Uang, B.-J.; Hung, S.-C., Synthesis of a Furanosyl-pyranone Derivative Related to the Tri-O-heterocyclic Core of Herbicidins, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol. 59, 421-425, 2012
2012 Luo, S.-Y.; Tripathi, A.; Zulueta, M. M. L.; Hung, S.-C., 2-Allylphenyl Glycosides as Glycosyl Donors for Sugar Coupling, Carbohydrate Research, vol. 352, 197-201, 2012
2012 Hsu, Y.; Lu, X.-A.; Zulueta, M. M. L.; Tsai, C.-M.; Lin, K.-I; Hung, S.-C.; Wong, C.-H., Acyl and Silyl Group Effects in Reactivity-based One-pot Glycosylation: Synthesis of Embryonic Stem Cell Surface Carbohydrates Lc4 and IV2Fuc-Lc4, J. Am. Chem. Soc., vol. 134, 4549-4552, 2012
2012 Zulueta, M. M. L.; Lin, S.-Y.; Lin, Y.-T.; Huang, C.-J.; Wang, C.-C.; Ku, C.-C.; Shi, Z.; Chyan, C.-L.; Irene, D.; Lim, L.-H.; Tsai, T.-I; Hu, Y.-P.; Liu, J.-Y.; Chang, W.; Arco, S. D.; Wong, C.-H.; Hung, S.-C., α-Glycosylation by D-Glucosamine-Derived Donors: Synthesis of Heparosan and Heparin Analogs that Interact with Mycobacterial Heparin-Binding Hemagglutinin, J. Am. Chem. Soc., vol. 134(21), 8988-8995, 2012
2012 Hu, Y.-P.; Zhong, Y.-Q.; Chen, Z.-G.; Chen, C.-Y.; Shi, Z.; Zulueta, M. M. L.; Ku, C.-C.; Lee, P.-Y.; Wang, C.-C.; Hung, S.-C., Divergent Synthesis of 48 Heparan Sulfate-Based Disaccharides and Probing the Specific Sugar–Fibroblast Growth Factor-1 Interaction, J. Am. Chem. Soc., vol. 134(51), 20722-20727, 2012
2012 Trees-Juen Chuang)*, Feng-Chi Chen*, Yen-Zho Chen, Position-dependent correlations between the level of DNA methylation and the evolutionary rates of mammalian coding exons, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 109(39), 15841-15846 (impact factor: 9.737; ranking: 4/54: MULTIDISCIPLINARY SCIENCES), 2012
2012 Ming-Chih Wang, Feng-Chi Chen*, Yen-Zho Chen, Yao-Ting Huang, Trees-Juen Chuang*, LDGIdb: a database of gene interactions inferred from long-range strong linkage disequilibrium between pairs of SNPs., BMC Research Note, vol. 5, 212, 2012
2012 Jean-Christophe Gelly, Hsuan-Yu Lin, Alexandre G. de Brevern*, (Trees-Juen Chuang)*, Feng-Chi Chen*, Selective Constraint on Human Pre-mRNA Splicing by Protein Structural Properties, Genome Biology and Evolution, vol. 4(9), 842-851, 2012
2012 Hsu YC, Chen NC, Chen PC, Wang CC, Cheng WC, Wu HN, Identification of a small-molecule inhibitor of dengue virus using a replicon system., Archives of virology, vol. 157(4), 681-688, 2012
2012 Shih HW, Chang YF, Li WJ, Meng FC, Huang CY, Ma C, Cheng TJ, Wong CH, Cheng WC, Effect of the Peptide Moiety of Lipid II on Bacterial Transglycosylase., Angewandte Chemie-International Edition, vol. 51(40), 10123-10126, 2012
2012 Huang CY, Shih HW, Lin LY, Tien YW, Cheng TJ, Cheng WC, Wong CH, Ma C, Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism., Proceedings of the National Academy of Sciences of the United States of America, vol. 109(17), 6496-6501, 2012
2012 Hao-Wei Shih, Kuo-Ting Chen, Wei-Chieh Cheng*, One-pot synthesis of phosphate diesters and phosphonate monoesters via a combination of microwave-CCl3CN-pyridine coupling conditions, Tetrahedron Lett., vol. 53(2), 243-246, 2012
2012 Wei-Ting Chen, Chen-Jee Hong, Ya-Tzu Lin, Wen-Han Chang, He-Ting Huang, Jhih-Ying Liao, Chih-Ya Cheng, Hsiu-Chih Liu, (Yun-Ru Chen)*, Irene H Cheng *, Amyloid-beta (Abeta) D7H mutation increases oligomeric Abeta42 and alters properties of Abeta-zinc/copper assemblies , PLos One, vol. 7(4), e35807, 2012
2012 Yi-Hung Liao, Yu-Jen Chang, Yuji Yoshiike, Yun-Chorng Chang*, Yun-Ru Chen)*, Negatively charged gold nanoparticles inhibit Alzheimer's amyloid-beta fibrillization, induce fibril dissociation, and mitigate neurotoxicity, SMALL, vol. 8(23), 3631-3639, 2012
2012 Hwang LC, Bai CH, Sun CA, Chen CJ, Prevalence of metabolically healthy obesity and its impacts onincidences of hypertension,diabetes and the metabolic syndrome in Taiwan, Asia Pac J Clin Nutr, vol. 21, 227-233, 2012
2012 Lien WC, Chen CJ, Male gender is a risk factor for recurrent appendicitis following nonoperative treatment: reply, World J Surg, vol. 36, 488-489, 2012
2012 Hsu WL, Pan WH, Chien YC, Yu KJ, Cheng YJ, Chen JY, Liu MY, Hsu MM, Lou PJ, Chen IH, Yang CS, Hildesheim A, Chen CJ, Lowered risk of nasopharyngeal carcinoma and intake of plant vitamin, fresh fish, green tea and coffee: a Case-Control study in Taiwan, PLoS One, vol. 7(7), e41779, 2012
2012 Lee MH, Yang HI, Chen CJ, for the REVEAL-HCV Study Group, Long-term health outcomes of chronic hepatitis C patients: a review of findings from R.E.V.E.A.L.-HCV cohort study, BIOMEDICINE, vol. 2(3), 99-107, 2012
2012 Chuang LC, Chen HC, Chen CJ*, Human papillomavirus infection and gastrointestinal cancers: a review, Eur J Clin Med Oncol-EJCMO, vol. 4, 47-53, 2012
2012 Lan Q, Hsiung CA, Matsuo K, Hong YC, Seow A, Wang Z, Hosgood HD 3rd, Chen K, Wang JC, Chatterjee N, Hu W, Wong MP, Zheng W, Caporaso N, Park JY, Chen CJ, Kim YH, Kim YT, Landi MT, Shen H, Lawrence C, Burdett L, Yeager M, Yuenger J, Jacobs KB, Chang IS, Mitsudomi T, Kim HN, Chang GC, Bassig BA, Tucker M, Wei F, Yin Z, Wu C, An SJ, Qian B, Lee VH, Lu D, Liu J, Jeon HS, Hsiao CF, Sung JS, Kim JH, Gao YT, Tsai YH, Jung YJ, Guo H, Hu Z, Hutchinson A, Wang WC, Klein R, Chung CC, Oh IJ, Chen KY, Berndt SI, He X, Wu W, Chang J, Zhang XC, Huang MS, Zheng H, Wang J, Zhao X, Li Y, Choi JE, Su WC, Park KH, Sung SW, Shu XO, Chen YM, Liu L, Kang CH, Hu L, Chen CH, Pao W, Kim YC, Yang TY, Xu J, Guan P, Tan W, Su J, Wang CL, Li H, Sihoe AD, Zhao Z, Chen Y, Choi YY, Hung JY, Kim JS, Yoon HI, Cai Q, Lin CC, Park IK, Xu P, Dong J, Kim C, He Q, Perng RP, Kohno T, Kweon SS, Chen CY, Vermeulen R, Wu J, Lim WY, Chen KC, Chow WH, Ji BT, Chan JK, Chu M, Li YJ, Yokota J, Li J, Chen H, Xiang YB, Yu CJ, Kunitoh H, Wu G, Jin L, Lo YL, Shiraishi K, Chen YH, Lin HC, Wu T, Wu YL, Yang PC, Zhou B, Shin MH, Fraumeni JF Jr, Lin D, Chanock SJ, Rothman N, Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia, Nature Genetics, vol. 44(12), 1330-1335, 2012
2012 Shen J, Wang S, Zhang YJ, Kappil MA, Wu HC, Kibriya MG, Wang Q, Jasmine F, Ahsan H, Lee PH, Yu MW, Chen CJ, Santella RM*, Genome-wide aberrant DNA methylation of microRNA host genes in hepatocellular carcinoma, Epigenetics, vol. 7(11), 1230-1237, 2012
2012 Hosgood HD III, Wang WC, Hong YC, Wang JC, Chen K, Chang IS, Chen CJ, Lu D, Yin Z, Wu C, Zheng W, Qian B, Park JY, Kim YH, Chatterjee N, Chen Y, Chang GC, Hsiao CF, Yeager M, Tsai YH, Wei H, Kim YT, Wu W, Zhao Z, Chow WH, Zhu X, Lo YL, Sung SW, Chen KY, Yuenger J, Kim JH, Huang L, Chen YH, Gao Y, Kim JH, Huang MS, Jung TH, Caporaso N, Zhao X, Huan Z, Yu D, Kim CH, Su WC, Shu X, Kim IS, Bassig B, Chen YM, Cha SI, Tan W, Chen H, Yang TY, Sung JS, Wang CL, Li X, Park KH, Yu CJ, Ryu JS, Xiang Y, Hutchinson A, Kim JS, Cai Q, Landi MT, Lee KM, Hung JY, Park JY, Tucker M, Lin CC, Ren Y, Perng RP, Chen CY, Li J, Chen KC, Li YJ, Chiu YF, Tsai FY, Yang PC, Fraumeni JF Jr, Seow A, Lin D, Zhou B, Chanock S, Hsiung CA, Rothman N, Lan Q, Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia, Human Genetics, vol. 131(7), 1197-1203, 2012
2012 Liao SF, Yang HI, Lee MH, Chen CJ, Lee WC*, Fifteen-year population attributable fractions and causal pies of risk factprs for newly developed hepatocellular carcinoma in 11,801 male residents in Taiwan, PLoS One, vol. 7, e34779, 2012