| 2025 |
Lo JM, Kung CC, (Cheng TR, Wong CH, Ma C, Structure-Based Mechanism and Specificity of Human Galactosyltransferase beta3GalT5., Journal of the American Chemical Society, vol. 147(13), 10875-10885, 2025任職中研院著作;
|
| 2025 |
Chang YC, Hsieh ML, Lee HL, Hee SW, Chang CF, Yen HY, Chen YA, Chen YR, Chou YW, Li FA, Ke YY, Chen SY, Hung MS, Hung AF, Huang JY, Chiu CH, Lin SY, Shih SF, Hsu CN, Hwang JJ, Yeh TK, (Cheng TR, Liao KC, Laio D, Lin SW, Chen TY, Hu CM, Vogel U, Saar D, Kragelund BB, Tsou LK, Tseng YH, Chuang LM, Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity., EMBO molecular medicine, vol. 17(5), 938-966, 2025任職中研院著作;
|
| 2025 |
Shimabukuro J, Shen CH, Hsueh TK, Chen TW, Tseng YC, Gannedi V, Dumalaog JS, Chang CH*, (Cheng TR)*, Yu CS*, Hung SC*, Streamlined Synthesis and Immunomodulatory Effects of Ulvan Oligosaccharides from Marine Green Algae., Journal of the American Chemical Society, vol. 147(36), 32951-32962, 2025任職中研院著作;
|
| 2024 |
Fan CY, Wang SW, Chung C, Chen JY, Chang CY, Chen YC, Hsu TL, (Cheng TR, Wong CH*, Synthesis of a dendritic cell-targeted self-assembled polymeric nanoparticle for selective delivery of mRNA vaccines to elicit enhanced immune responses., Chemical science, vol. 15(29), 11626-11632, 2024任職中研院著作;
|
| 2024 |
Tseng YW, Yang TJ, Hsu YL, Liu JH, Tseng YC, Hsu TW, Lu Y, Pan SH, * (Cheng TR, *) Fang JM*, Dual-targeting compounds possessing enhanced anticancer activity via microtubule disruption and histone deacetylase inhibition., European journal of medicinal chemistry, vol. 265, 116042, 2024具代表性; 任職中研院著作;
|
| 2023 |
Tseng YL, Lu PC, Lee CC, He RY, Huang YA, Tseng YC, (Cheng TR, Huang JJ*, Fang JM, Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera., Journal of biomedical science, vol. 30(1), 27, 2023任職中研院著作;
|
| 2022 |
Li J, Hsiung SY, Kao MR, Xing X, Chang SC, Wang D, Hsieh PY, Liang PH, Zhu Z, (Cheng TR, Shie JJ, Liou JP, Abbott DW, Kwon SW, Hsieh YSY*, Structural compositions and biological activities of cell wall polysaccharides in the rhizome, stem, and leaf of Polygonatum odoratum (Mill.) Druce., Carbohydrate research, vol. 521, 108662, 2022任職中研院著作;
|
| 2022 |
Chen WA, Chen YH, Hsieh CY, Hung PF, Chen CW, Chen CH, Lin JL, (Cheng TR, Hsu TL, Wu YT, Shen CN, Cheng WC, Harnessing natural-product-inspired combinatorial chemistry and computation-guided synthesis to develop N-glycan modulators as anticancer agents., Chemical science, vol. 13(21), 6233-6243, 2022任職中研院著作;
|
| 2022 |
Tseng KY, Tzeng ZH, (Cheng TR, Liang PH, Hung SC, Design and Synthesis of 1-O- and 6'-C-Modified Heparan Sulfate Trisaccharides as Human Endo-6-O-Sulfatase 1 Inhibitors., Frontiers in chemistry, vol. 10, 947475, 2022任職中研院著作;
|
| 2022 |
Huang HY, Liao HY, Chen X, Wang SW, Cheng CW, Shahed-Al-Mahmud M, Liu YM, Mohapatra A, Chen TH, Lo JM, Wu YM, Ma HH, Chang YH, Tsai HY, Chou YC, Hsueh YP, Tsai CY, Huang PY, Chang SY, Chao TL, Kao HC, Tsai YM, Chen YH, Wu CY, Jan JT, (Cheng TJR, Lin KI, Ma C, Wong CH, Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models., Science translational medicine, vol. 14(639), eabm0899, 2022任職中研院著作;
|
| 2022 |
Chuang HC, Liu MF, Wu HY, Wu YT, (Cheng TJR, Fang JM, Photoaffinity labeling of benzophenone-containing salicylanilide compounds to give an insight into the mechanism in disrupting peptidoglycan formation., Bioorganic & medicinal chemistry, vol. 67, 116819, 2022任職中研院著作;
|
| 2021 |
Chang SY, Huang KY, Chao TL, Kao HC, Pang YH, Lu L, Chiu CL, Huang HC, (Cheng TR, Fang JM, * Yang PC*, Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses., Scientific reports, vol. 11(1), 8692, 2021任職中研院著作;
|
| 2021 |
Shivatare SS, Cheng TR, Cheng YY, Shivatare VS, Tsai TI, Chuang HY, Wu CY, Wong CH*, Immunogenicity Evaluation of N-Glycans Recognized by HIV Broadly Neutralizing Antibodies., ACS chemical biology, vol. 16(10), 2016-2025, 2021任職中研院著作;
|
| 2021 |
Jan JT, (Cheng TR, Juang YP, Ma HH, Wu YT, Yang WB, Cheng CW, Chen X, Chou TH, Shie JJ, Cheng WC, Chein RJ, Mao SS, Liang PH, Ma C, Hung SC, Wong CH, Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection., Proceedings of the National Academy of Sciences of the United States of America, vol. 118(5), e2021579112, 2021任職中研院著作;
|
| 2021 |
Ko YA, Yu YH, Wu YF, Tseng YC, Chen CL, Goh KS, Liao HY, Chen TH, (Cheng TR, Yang AS, Wong CH, Ma C, Lin KI, A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells., PLoS pathogens, vol. 17(8), e1009724, 2021任職中研院著作;
|
| 2020 |
Chiu LT, Sabbavarapu NM, Lin WC, Fan CY, Wu CC, (Cheng TR, Wong CH, Hung SC, Trisaccharide Sulfate and Its Sulfonamide as an Effective Substrate and Inhibitor of Human Endo-O-sulfatase-1., Journal of the American Chemical Society, vol. 142(11), 5282-5292, 2020任職中研院著作;
|
| 2020 |
Lin CY, Wu HY, Hsu YL, (Cheng TR, Liu JH, Huang RJ, Hsiao TH, Wang CJ, Hung PF, Lan A, Pan SH, Chein RJ, Wong CH, Yang PC, Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein., Journal of medicinal chemistry, vol. 63(6), 3172-3187, 2020任職中研院著作;
|
| 2020 |
Wang WF, Lu MJ, (Cheng TR, Tang YC, Teng YC, Hwa TY, Chen YH, Li MY, Wu MH, Chuang PC, Jou R, Wong CH, Li WH, Genomic Analysis of Mycobacterium tuberculosis Isolates and Construction of a Beijing Lineage Reference Genome., Genome biology and evolution, vol. 12(2), 3890-3905, 2020任職中研院著作;
|
| 2020 |
Woodring JL, Lu SH, Krasnova L, Wang SC, Chen JB, Chou CC, Huang YC, Cheng TR, Wu YT, Chen YH, Fang JM, Tsai MD, Wong CH, Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein, Journal of medicinal chemistry, vol. 63(1), 205-215, 2020任職中研院著作;
|
| 2020 |
Liao HY, Wang SC, Ko YA, Lin KI, Ma C, (Cheng TR, Wong CH, Chimeric hemagglutinin vaccine elicits broadly protective CD4 and CD8 T cell responses against multiple influenza strains and subtypes., Proceedings of the National Academy of Sciences of the United States of America, vol. 117(30), 17757-17763, 2020任職中研院著作;
|
| 2020 |
Woodring JL, Lu SH, Krasnova L, Wang SC, Chen JB, Chou CC, Huang YC, (Cheng TR, Wu YT, Chen YH, Fang JM, Tsai MD, Wong CH, Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein., Journal of medicinal chemistry, vol. 63(1), 205-215, 2020任職中研院著作;
|
| 2019 |
Li J, Wang D, Xing X, (Cheng TR, Liang PH, Bulone V, Park JH, Hsieh YSY*, Structural analysis and biological activity of cell wall polysaccharides extracted from Panax ginseng marc., International journal of biological macromolecules, vol. 135, 29-37, 2019任職中研院著作;
|
| 2019 |
Hong BT, Cheng YE, (Cheng TJ, Fang JM*, Boronate, trifluoroborate, sulfone, sulfinate and sulfonate congeners of oseltamivir carboxylic acid: Synthesis and anti-influenza activity., European journal of medicinal chemistry, vol. 163, 710-721, 2019任職中研院著作;
|
| 2019 |
Wang SC, Liao HY, Zhang JY, (Cheng TR, *) Wong CH*, Development of a universal influenza vaccine using hemagglutinin stem protein produced from Pichia pastoris., Virology, vol. 526, 125-137, 2019具代表性; 任職中研院著作;
|
| 2019 |
Huang MR, Hsu YL, Lin TC, (Cheng TR, Li LW, Tseng YW, Chou YS, Liu JH, Pan SH, Fang JM, * Wong CH, Structure-guided development of purine amide, hydroxamate, and amidoxime for the inhibition of non-small cell lung cancer., European journal of medicinal chemistry, vol. 181, 111551, 2019任職中研院著作;
|
| 2019 |
Lin MS, Hong TM, Chou TH, Yang SC, Chung WC, Weng CW, Tsai ML, (Cheng TR, Chen JJW, Lee TC, Wong CH, Chein RJ, * Yang PC*, 4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of beta-tubulin., European journal of medicinal chemistry, vol. 181, 111584, 2019任職中研院著作;
|
| 2019 |
Chen MH, Huang MT, Yu WK, Lee SS, Wang JH, (Cheng TR, Bowman MR, Hsieh SL*, Antibody blockade of Dectin-2 suppresses house dust mite-induced Th2 cytokine production in dendritic cell- and monocyte-depleted peripheral blood mononuclear cell co-cultures from asthma patients., Journal of biomedical science, vol. 26(1), 97, 2019任職中研院著作;
|
| 2018 |
Wang PC, Chiu DC, Jan JT, Huang WI, Tseng YC, Li TT, (Cheng TJ, Tsai KC, Fang JM*, Peramivir conjugates as orally available agents against influenza H275Y mutant., European journal of medicinal chemistry, vol. 145, 224-234, 2018任職中研院著作;
|
| 2018 |
Huang SF, Lin CH, Lai YT, Tsai CL, (Cheng TR, Wang SK*, Development of Pseudomonas aeruginosa Lectin LecA Inhibitor by using Bivalent Galactosides Supported on Polyproline Peptide Scaffolds., Chemistry, an Asian journal, vol. 13(6), 686-700, 2018任職中研院著作;
|
| 2018 |
Wu WS, Cheng WC, (Cheng TR, * Wong CH*, Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase., Journal of the American Chemical Society, vol. 140, 2752-2755, 2018具代表性; 任職中研院著作;
|
| 2018 |
Hsu PH, Chiu DC, Wu KL, Lee PS, Jan JT, Cheng YE, Tsai KC, (Cheng TR, Fang JM*, Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses., European journal of medicinal chemistry, vol. 154, 314-323, 2018任職中研院著作;
|
| 2018 |
Cheng HW, Chein RJ, (Cheng TJ, Wu PS, Wu HY, Hung PF, Wang CJ, Hsu YL, Wong JM, Yuan A, Wong CH, Yang PC, Pan SH*, 2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction., Cancer science, vol. 109(3), 832-842, 2018任職中研院著作;
|
| 2018 |
Wang X, Krasnova L, Wu KB, Wu WS, (Cheng TR, Wong CH*, Towards new antibiotics targeting bacterial transglycosylase: Synthesis of a Lipid II analog as stable transition-state mimic inhibitor., Bioorganic & medicinal chemistry letters, vol. 28(16), 2708-2712, 2018任職中研院著作;
|
| 2017 |
Huang LY, Wang SC, (Cheng TR, * Wong CH*, Undecaprenyl Phosphate Phosphatase Activity of Undecaprenol Kinase Regulates the Lipid Pool in Gram-Positive Bacteria., Biochemistry, vol. 56(40), 5417-5427, 2017具代表性; 任職中研院著作;
|
| 2017 |
Chiu DC, Lin TC, Huang WI, (Cheng TJ, Tsai KC, Fang JM*, Peramivir analogues bearing hydrophilic side chains exhibit higher activities against H275Y mutant than wild-type influenza virus., Organic & biomolecular chemistry, vol. 15(46), 9910-9922, 2017任職中研院著作;
|
| 2017 |
Chen KT, Lin CK, Guo CW, Chang YF, Hu CM, Lin HH, Lai Y, (Cheng TR, Cheng WC*, Effect of the lipid II sugar moiety on bacterial transglycosylase: the 4-hydroxy epimer of lipid II is a TGase inhibitor., Chemical communications (Cambridge, England), vol. 53(4), 771-774, 2017任職中研院著作;
|
| 2016 |
Chen KT, Chen PT, Lin CK, Huang LY, Hu CM, Chang YF, Hsu HT, Cheng TJ, Wu YT, Cheng WC, Structural Investigation of Park |
s Nucleotide on Bacterial Translocase MraY: Discovery of Unexpected MraY Inhibitors., Scientific reports, vol. 6, 31579, 2016任職中研院著作;
| 2016 |
Kuo TC, Li LW, Pan SH, * Fang JM, * Liu JH, (Cheng TJ, Wang CJ, Hung PF, Chen HY, Hong TM, Hsu YL, Wong CH, Yang PC, Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin., Journal of medicinal chemistry, vol. 59(18), 8521-34, 2016任職中研院著作;
|
| 2016 |
Wang PC, Fang JM, * Tsai KC, Wang SY, Huang WI, Tseng YC, Cheng YS, (Cheng TJ, Wong CH, Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors., Journal of medicinal chemistry, vol. 59, 5297-5310, 2016任職中研院著作;
|
| 2015 |
Patil PS, (Cheng TJ, Zulueta MM, Yang ST, Lico LS, Hung SC*, Total synthesis of tetraacylated phosphatidylinositol hexamannoside and evaluation of its immunomodulatory activity., Nature communications, vol. 6, 7239-7247, 2015任職中研院著作;
|
| 2015 |
Lin MI, Su BH, Lee CH, Wang ST, Wu WC, Dangate P, Wang SY, Huang WI, (Cheng TJ, Lin OA, Cheng YS, * Tseng YJ, * Sun CM*, Synthesis and inhibitory effects of novel pyrimido-pyrrolo-quinoxalinedione analogues targeting nucleoproteins of influenza A virus H1N1., European journal of medicinal chemistry, vol. 102, 477-486, 2015任職中研院著作;
|
| 2015 |
Zuegg J, Muldoon C, Adamson G, McKeveney D, Le Thanh G, Premraj R, Becker B, Cheng M, Elliott AG, Huang JX, Butler MS, Bajaj M, Seifert J, Singh L, Galley NF, Roper DI, Lloyd AJ, Dowson CG, (Cheng TJ, Cheng WC, Demon D, Meyer E, Meutermans W, Cooper M*A, Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity., Nature communications, vol. 6, 7719-7729, 2015任職中研院著作;
|
| 2014 |
Lee HY, Chen CY, Tsai TI, Li ST, Lin KH, Cheng YY, Ren CT, Cheng TJ, Wu CY, Wong CH, Immunogenicity study of Globo H analogues with modification at the reducing or nonreducing end of the tumor antigen., Journal of the American Chemical Society, vol. 136(48), 16844-53, 2014任職中研院著作;
|
| 2014 |
Hsu CH, Schelwies M, Enck S, Huang LY, Huang SH, Chang YF, Cheng TJ, Cheng WC, Wong CH, Iminosugar C-glycoside analogues of alpha-D-GlcNAc-1-phosphate: synthesis and bacterial transglycosylase inhibition., The Journal of organic chemistry, vol. 79(18), 8629-8637, 2014任職中研院著作;
|
| 2014 |
Huang LY, Huang SH, Chang YC, Cheng WC, Cheng TJ, Wong CH, Enzymatic synthesis of lipid II and analogues., Angewandte Chemie-International Edition, vol. 53, 8060-8065, 2014具代表性; 任職中研院著作;
|
| 2014 |
Chen YS, Yu HM, Shie JJ, Cheng TJ, Wu CY, Fang JM, Wong CH, Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity., Bioorganic & medicinal chemistry, vol. 22(5), 1766-1772, 2014任職中研院著作;
|
| 2013 |
Wang CH, Li ST, Lin TL, Cheng YY, Sun TH, Wang JT, Cheng TJ, Mong KK, Wong CH, Wu CY, Synthesis of Neisseria meningitidis serogroup W135 capsular oligosaccharides for immunogenicity comparison and vaccine development., Angewandte Chemie-International Edition, vol. 52(35), 9157-9161, 2013任職中研院著作;
|
| 2013 |
Chuang HY, Ren CT, Chao CA, Wu CY, Shivatare SS, Cheng TJ, Wu CY, Wong CH, Synthesis and vaccine evaluation of the tumor-associated carbohydrate antigen RM2 from prostate cancer., Journal of the American Chemical Society, vol. 135(30), 11140-11150, 2013任職中研院著作;
|
| 2013 |
Ohara K, Lin CC, Yang PJ, Hung WT, Yang WB, Cheng TJ, Fang JM, Wong CH, Synthesis and bioactivity of beta-(1-->4)-linked oligomannoses and partially acetylated derivatives., The Journal of organic chemistry, vol. 78(13), 6390-6411, 2013任職中研院著作;
|
| 2013 |
Chen KT, Kuan YC, Fu WC, Liang PH, Cheng TJ, Wong CH, Cheng WC, Rapid preparation of mycobacterium N-glycolyl Lipid I and Lipid II derivatives: a biocatalytic approach., Chemistry-a European Journal, vol. 19(3), 834-838, 2013任職中研院著作;
|
| 2013 |
Huang SH, Wu WS, Huang LY, Huang WF, Fu WC, Chen PT, Fang JM, Cheng WC, Cheng TJ, Wong CH, New continuous fluorometric assay for bacterial transglycosylase using forster resonance energy transfer., Journal of the American Chemical Society, vol. 135(45), 17078-17089, 2013具代表性; 任職中研院著作;
|
| 2013 |
Huang SH, Wu WS, Huang LY, Huang WF, Fu WC, Chen PT, Fang JM, Cheng WC, Cheng TJ, Wong CH, New continuous fluorometric assay for bacterial transglycosylase using Forster resonance energy transfer., Journal of the American Chemical Society, vol. 135(45), 17078-89, 2013任職中研院著作;
|
| 2013 |
Tsai TI, Lee HY, Chang SH, Wang CH, Tu YC, Lin YC, Hwang DR, Wu CY, Wong CH, Effective sugar nucleotide regeneration for the large-scale enzymatic synthesis of Globo H and SSEA4., Journal of the American Chemical Society, vol. 135(39), 14831-14839, 2013任職中研院著作;
|
| 2013 |
Cheng TJ, Wang SY, Wen WH, Su CY, Lin M, Huang WI, Liu MT, Wu HS, Wang NS, Cheng CK, Chen CL, Ren CT, Wu CY, Fang JM, Cheng YS, Wong CH, Chemical probes for drug-resistance assessment by binding competition (RABC): oseltamivir susceptibility evaluation., Angewandte Chemie-International Edition, vol. 52(1), 366-370, 2013任職中研院著作;
|
| 2013 |
Huang YL, Hung JT, Cheung SK, Lee HY, Chu KC, Li ST, Lin YC, Ren CT, Cheng TJ, Hsu TL, Yu AL, Wu CY, Wong CH, Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancer., Proceedings of the National Academy of Sciences of the United States of America, vol. 110(7), 2517-2522, 2013任職中研院著作;
|
| 2013 |
Cheng TJ, Wang SY, Wen WH, Su CY, Lin M, Huang WI, Liu MT, Wu HS, Wang NS, Cheng CK, Chen CL, Ren CT, Wu CY, Fang JM, Cheng YS, Wong CH, Chemical Probes for Drug-Resistance Assessment by Binding Competition (RABC): Oseltamivir Susceptibility Evaluation., ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 52(1), 366-370, 2013任職中研院著作;
|
| 2012 |
Liu KC, Fang JM, Jan JT, Cheng TJ, Wang SY, Yang ST, Cheng YS, Wong CH, Enhanced Anti-influenza Agents Conjugated with Anti-inflammatory Activity., Journal of medicinal chemistry, vol. 55(19), 8493-8501, 2012任職中研院著作;
|
| 2012 |
Shih HW, Chang YF, Li WJ, Meng FC, Huang CY, Ma C, Cheng TJ, Wong CH, Cheng WC, Effect of the peptide moiety of Lipid II on bacterial transglycosylase., Angewandte Chemie-International Edition, vol. 51(40), 10123-10126, 2012任職中研院著作;
|
| 2012 |
Cheng TJ, Weinheimer S, Tarbet EB, Jan JT, Cheng YS, Shie JJ, Chen CL, Chen CA, Hsieh WC, Huang PW, Lin WH, Wang SY, Fang JM, Hu OY, Wong CH, Development of Oseltamivir Phosphonate Congeners as Anti-influenza Agents., Journal of medicinal chemistry, vol. 55(20), 8657-8670, 2012任職中研院著作;
|
| 2012 |
Cheng TJ, Weinheimer S, Tarbet EB, Jan JT, Cheng YS, Shie JJ, Chen CL, Chen CA, Hsieh WC, Huang PW, Lin WH, Wang SY, Fang JM, Hu OY, Wong CH, Development of oseltamivir phosphonate congeners as anti-influenza agents., Journal of medicinal chemistry, vol. 55(20), 8657-8670, 2012任職中研院著作;
|
| 2012 |
Huang CY, Shih HW, Lin LY, Tien YW, Cheng TJ, Cheng WC, Wong CH, Ma C, Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism., Proceedings of the National Academy of Sciences of the United States of America, vol. 109(17), 6496-6501, 2012任職中研院著作;
|
| 2011 |
Meng FC, Chen KT, Huang LY, Shih HW, Chang HH, Nien FY, Liang PH, Cheng TJ, Wong CH, Cheng WC, Total synthesis of polyprenyl N-glycolyl lipid II as a mycobacterial transglycosylase substrate., Organic letters, vol. 13(19), 5306-5309, 2011任職中研院著作;
|
| 2011 |
Chen MW, Liao HY, Huang Y, Jan JT, Huang CC, Ren CT, Wu CY, Cheng TJ, Ho DD, Wong CH, Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin., Proceedings of the National Academy of Sciences of the United States of America, vol. 108(9), 3510-3515, 2011任職中研院著作;
|
| 2011 |
Shih HW, Chen KT, Cheng TJ, Wong CH, Cheng WC, A new synthetic approach toward bacterial transglycosylase substrates, Lipid II and Lipid IV., Organic letters, vol. 13(17), 4600-4603, 2011任職中研院著作;
|
| 2010 |
Shie JJ, Chen CA, Lin CC, Ku AF, Cheng TJ, Fang JM, Wong CH, Regioselective synthesis of di-C-glycosylflavones possessing anti-inflammation activities., Organic & biomolecular chemistry, vol. 8(19), 4451-4462, 2010任職中研院著作;
|
| 2010 |
Su CY, Cheng TJ, Lin MI, Wang SY, Huang WI, Lin-Chu SY, Chen YH, Wu CY, Lai MM, Cheng WC, Wu YT, Tsai MD, Cheng YS, Wong CH, High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity., Proceedings of the National Academy of Sciences of the United States of America, vol. 107(45), 19151-19156, 2010具代表性; 任職中研院著作;
|
| 2010 |
Cheng TJ, Wu YT, Yang ST, Lo KH, Chen SK, Chen YH, Huang WI, Yuan CH, Guo CW, Huang LY, Chen KT, Shih HW, Cheng YS, Cheng WC, Wong CH, High-throughput identification of antibacterials against methicillin-resistant Staphylococcus aureus (MRSA) and the transglycosylase., Bioorganic & medicinal chemistry, vol. 18(24), 8512-8529, 2010具代表性; 任職中研院著作;
|
| 2010 |
Liao HY, Hsu CH, Wang SC, Liang CH, Yen HY, Su CY, Chen CH, Jan JT, Ren CT, Chen CH, Cheng TJ, Wu CY, Wong CH, Differential receptor binding affinities of influenza hemagglutinins on glycan arrays., Journal of the American Chemical Society, vol. 132(42), 14849-14856, 2010具代表性; 任職中研院著作;
|
| 2010 |
Shih HW, Chen KT, Chen SK, Huang CY, Cheng TJ, Ma C, Wong CH, Cheng WC, Combinatorial approach toward synthesis of small molecule libraries as bacterial transglycosylase inhibitors., Organic & biomolecular chemistry, vol. 8(11), 2586-2593, 2010任職中研院著作;
|
| 2009 |
Wang SY, Su CY, Lin M, Huang SY, Huang WI, Wang CC, Wu YT, Cheng TJ, Yu HM, Ren CT, Wu CY, Wong CH, Cheng YS, HA-pseudotyped retroviral vectors for influenza antagonist screening, Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, vol. 14(3), 294-302, 2009任職中研院著作;
|
| 2008 |
Tsou EL, Chen SY, Yang MH, Wang SC, Cheng TR, Cheng WC, Synthesis and biological evaluation of a 2-aryl polyhydroxylated pyrrolidine alkaloid-based library., Bioorganic & medicinal chemistry, vol. 16(24), 10198-10204, 2008任職中研院著作;
|
| 2008 |
Hsieh YS, Chien C, Liao SK, Liao SF, Hung WT, Yang WB, Lin CC, Cheng TJ, Chang CC, Fang JM, Wong CH, Structure and bioactivity of the polysaccharides in medicinal plant Dendrobium huoshanense., Bioorganic & medicinal chemistry, vol. 16(11), 6054-6068, 2008任職中研院著作;
|
| 2008 |
Cheng TJ, Sung MT, Liao HY, Chang YF, Chen CW, Huang CY, Chou LY, Wu YD, Chen YH, Cheng YS, Wong CH, Ma C, Cheng WC, Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics., Proceedings of the National Academy of Sciences of the United States of America, vol. 105(2), 431-436, 2008具代表性; 任職中研院著作;
|
| 2008 |
Chen MW, Cheng TJ, Huang Y, Jan JT, Ma SH, Yu AL, Wong CH, Ho DD, A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses., Proceedings of the National Academy of Sciences of the United States of America, vol. 105(36), 13538-13543, 2008任職中研院著作;
|
| 2004 |
Cheng TJ, Brik A, Wong CH, Kan CC, Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitors in Escherichia coli., Antimicrobial agents and chemotherapy, vol. 48(7), 2437-2447, 2004
|
| 2003 |
Cheng TJ, Tseng YF, Chang WM, Chang MD, Lai YK, Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2., Journal of cellular biochemistry, vol. 89(3), 589-602, 2003
|
| 2002 |
Cheng TJ, Rey PG, Poon T, Kan CC, Kinetic studies of human tyrosyl-DNA phosphodiesterase, an enzyme in the topoisomerase I DNA repair pathway., European journal of biochemistry / FEBS, vol. 269(15), 3697-3704, 2002
|
| 2000 |
Cheng TJ, Lin YL, Chiang AS, Lai YK, Association of protein phosphatase 2A with its substrate vimentin intermediate filaments in 9L rat brain tumor cells., Journal of cellular biochemistry, vol. 79(1), 126-138, 2000
|
| 1998 |
Hung JJ, Cheng TJ, Chang MD, Chen KD, Huang HL, Lai YK, Involvement of heat shock elements and basal transcription elements in the differential induction of the 70-kDa heat shock protein and its cognate by cadmium chloride in 9L rat brain tumor cells., Journal of cellular biochemistry, vol. 71(1), 21-35, 1998
|
| 1998 |
Cheng TJ, Chen TM, Chen CH, Lai YK, Induction of stress response and differential expression of 70 kDa stress proteins by sodium fluoride in HeLa and rat brain tumor 9L cells., Journal of cellular biochemistry, vol. 69(2), 221-231, 1998
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| 1998 |
Cheng TJ, Lai YK, Identification of mitogen-activated protein kinase-activated protein kinase-2 as a vimentin kinase activated by okadaic acid in 9L rat brain tumor cells., Journal of cellular biochemistry, vol. 71(2), 169-181, 1998
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| 1998 |
Hung JJ, Cheng TJ, Lai YK, Chang MD, Differential activation of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinases confers cadmium-induced HSP70 expression in 9L rat brain tumor cells., The Journal of biological chemistry, vol. 273(48), 31924-31931, 1998
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| 1998 |
Wang TT, Chiang AS, Chu JJ, Cheng TJ, Chen TM, Lai YK, Concomitant alterations in distribution of 70 kDa heat shock proteins, cytoskeleton and organelles in heat shocked 9L cells., The international journal of biochemistry & cell biology, vol. 30(6), 745-759, 1998
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| 1994 |
Cheng TJ, Lai YK, Transient increase in vimentin phosphorylation and vimentin-HSC70 association in 9L rat brain tumor cells experiencing heat-shock., Journal of cellular biochemistry, vol. 54(1), 100-109, 1994
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| 1994 |
Perng MD, Cheng TJ, Chen CM, Lai YK, Induction of aggregation and augmentation of protein kinase-mediated phosphorylation of purified vimentin intermediate filaments by withangulatin A., Molecular pharmacology, vol. 46(4), 612-617, 1994
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![HTS_1024[1]](/uploads/asset/data/680060fc367376d4c876c212/HTS_1024_1_.jpg "HTS_1024[1]")
