EDUCATION AND POSITIONS HELD:
- Ph.D., Chemistry, Iowa State University (1985)
- Postdoctoral Fellow, Ames National Laboratory (1986-1987)
- Assistant Chemist, Ames National Laboratory (1988-1992)
- Associate Chemist, Ames National Laboratory (1993-1997)
- Chemist, Ames National Laboratory (1997-2001)
- Principal Investigator of R&D Core Facility (Chemical/Isotope Labeling for Quantitative Proteomics) at National Program for Genomic Medicine (2001-2004)
- Research Scientist, supervise mass spectrometry facilities and coordinate mass spectrometry-related technical development of Key Technology division at Genomics Research Center.
The combined technologies of separation science and mass spectrometry are the current workhorse in proteomics. A large scale and unbiased non-gel based quantitative proteomics platform which incorporates multi-dimensional chromatography, isotope labeling techniques and mass spectrometry to elucidate protein identification and differential protein expression for the discovery of diagnostic and/or prognostic markers of disease and cancer studies. Our interests are mainly focusing on developing technologies platform to characterize low abundance proteins and elucidate proteins post-translational modifications and provide quantitative protein information at the same time.