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RRM1 O-GlcNAcylation inhibition suppresses pancreatic cancer via TK1-mediated replication stress

RRM1 O-GlcNAcylation inhibition suppresses pancreatic cancer via TK1-mediated replication stress

Chun-Mei Hu
Cancer Gene Therapy
March 28, 2025

Tau destabilization in a familial deletion mutant K280 accelerates its fibrillization and enhances the seeding effect

Tau destabilization in a familial deletion mutant K280 accelerates its fibrillization and enhances the seeding effect

Yun-Ru (Ruby) Chen
Journal of Biological Chemistry
February 8, 2025

Innovative cyclic peptide disrupts IL-17RB–MLK4 interaction for targeted pancreatic cancer therapy

Innovative cyclic peptide disrupts IL-17RB–MLK4 interaction for targeted pancreatic cancer therapy

Chun-Mei Hu
Biomedicine & Pharmacotherapy
February 5, 2025

Tacrolimus regulates extracellular vesicle secretion from T cells via autophagy-lysosomal pathway

Tacrolimus regulates extracellular vesicle secretion from T cells via autophagy-lysosomal pathway

Chun-Mei Hu, Po-Huang Lee
Biomedicine & Pharmacotherapy
December 17, 2024

Glycoengineering for a Universal COVID-19 Vaccine

Glycoengineering for a Universal COVID-19 Vaccine

Chi-Huey Wong
Scientia
October 30, 2024

SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front

SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front

Chun-Mei Hu
Cancer Gene Therapy
October 24, 2024

Reverse hierarchical DED assembly in the cFLIP-procaspase-8 and cFLIP-procaspase-8-FADD complexes

Reverse hierarchical DED assembly in the cFLIP-procaspase-8 and cFLIP-procaspase-8-FADD complexes

Su-Chang Lin
Nature Communications
October 17, 2024

B4GALT1-dependent galectin-8 binding with TGF-β receptor suppresses colorectal cancer progression and metastasis

B4GALT1-dependent galectin-8 binding with TGF-β receptor suppresses colorectal cancer progression and metastasis

Kuo-I Lin
Cell Death & Disease
September 4, 2024

Synthesis of a dendritic cell-targeted self-assembled polymeric nanoparticle for selective delivery of mRNA vaccines to elicit enhanced immune responses

Synthesis of a dendritic cell-targeted self-assembled polymeric nanoparticle for selective delivery of mRNA vaccines to elicit enhanced immune responses

Chi-Huey Wong
Chemical Science
June 25, 2024

Exosomal miRNA 16-5p/29a-3p from pancreatic cancer induce adipose atrophy by inhibiting adipogenesis and promoting lipolysis

Exosomal miRNA 16-5p/29a-3p from pancreatic cancer induce adipose atrophy by inhibiting adipogenesis and promoting lipolysis

Chun-Mei Hu
iScience
June 20, 2024

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