Chemical Biology Division 2015

Chen, Yun-Ru Ruby

  • Yi-Hung Liao and Yun-Ru Chen*, 2015, “A novel method for expression and purification of authentic amyloid-β with and without 15N labels.”, PROTEIN EXPRESSION AND PURIFICATION, 113, 63-71. (SCIE) (IF: 1.513; SCIE ranking: 83.1%,87.2%,83.3%)
  • Patricia F. Kao, Yun-Ru Chen, Xiao-Bo Liu, Charles DeCarli, William W. Seeley, and Lee-Way Jin*, 2015, “Detection of TDP-43 oligomers in frontotemporal lobar degeneration-TDP”, ANNALS OF NEUROLOGY, 78(2), 211-221. (SCIE) (IF: 9.037; SCIE ranking: 4.4%,6.6%)

Cheng, Wei-Chieh

  • Zuegg J, Muldoon C, Adamson G, McKeveney D, Le Thanh G, Premraj R, Becker B, Cheng M, Elliott AG, Huang JX, Butler MS, Bajaj M, Seifert J, Singh L, Galley NF, Roper DI, Lloyd AJ, Dowson CG, Cheng TJ, Cheng WC, Demon D, Meyer E, Meutermans W, Cooper MA, 2015, “Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.”, Nature communications, 6, 7719. (SCIE) (IF: 12.121; SCIE ranking: 8.5%)
  • Chen PT, Lin CK, Tsai CJ, Huang DY, Nien FY, Lin WW, Cheng WC, 2015, “Expeditious Synthesis of Enantiopure, Orthogonally Protected Bis-alpha-Amino Acids (OPBAAs) and their Use in a Study of Nod1 Stimulation.”, Chemistry-An Asian Journal, 10(2), 474-482. (SCIE) (IF: 4.056; SCIE ranking: 30.5%)
  • Cheng WC, Guo CW, Lin CK, Jiang YR, 2015, “Synthesis and Inhibition Study of Bicyclic Iminosugar-​Based Alkaloids, Scaffolds, and Libraries towards Glucosidase”, Israel Journal of Chemistry, 55(3-4), 403-411. (SCIE) (IF: 2.32; SCIE ranking: 52%)
  • Lin CK, Chen KT, Hu CM, Yun WY, Cheng WC, 2015, “Synthesis of 1-C-Glycoside-Linked Lipid II Analogues Toward Bacterial Transglycosylase Inhibition.”, Chemistry-A European Journal, 21(20), 7511-7519. (SCIE) (IF: 4.857; SCIE ranking: 24.9%)
  • Chen KT, Huang DY, Chiu CH, Lin WW, Liang PH, Cheng WC, 2015, “Synthesis of Diverse N-Substituted Muramyl Dipeptide Derivatives and Their Use in a Study of Human NOD2 Stimulation Activity.”, Chemistry-A European Journal, 21(34), 11984-11988. (SCIE) (IF: 4.857; SCIE ranking: 24.9%)
  • Lin CK, Cheng LW, Li HY, Yun WY, Cheng WC, 2015, “Synthesis of novel polyhydroxylated pyrrolidine-triazole/-isoxazole hybrid molecules.”, Organic & biomolecular chemistry, 13(7), 2100-2107. (SCIE) (IF: 3.412; SCIE ranking: 22.8%)

Hung, Shang-Cheng

  • Kuwabara K; Nishitsuji K; Uchimura K; Hung SC; Mizuguchi M; Nakajima H; Mikawa S; Kobayashi N; Saito H; Sakashita N., 2015, “Cellular interaction and cytotoxicity of the Iowa mutation of apolipoprotein A-I (ApoA-IIowa) amyloid mediated by sulfate moieties of heparan sulfate.”, JOURNAL OF BIOLOGICAL CHEMISTRY, 290, 24210-24221. (SCIE) (IF: 4.238; SCIE ranking: 29.3%)
  • Medel Manuel L. Zulueta, Donala Janreddy andShang-Cheng Hung, 2015, “One-Pot Methods for the Protection and Assembly of Sugars”, ISRAEL JOURNAL OF CHEMISTRY, 55(3), 347-359. (SCIE) (IF: 2.32; SCIE ranking: 52%)
  • Patil PS; Cheng TJR; Zulueta MM; Yang ST; Lico LS; Hung SC., 2015, “Total synthesis of tetraacylated phosphatidylinositol hexamannoside and evaluation of its immunomodulatory activity.”, Nat Commun., 6, 7239. (SCIE) (IF: 12.121; SCIE ranking: 8.5%)

Li, Tsung-Lin

  • T. H. Huang, Y. H. Chiu, Y. L. Chan, H. Wang, T. L. Li, Y. Chu, C. Y. Liu, C. T. Yang, T. Y. Lee, J. S. You, K. H. Hsu, C. J. Wu*, 2015, “Antrodia cinnamomea alleviates cisplatin-induced hepatotoxicity and enhances chemo-sensitivity of line-1 lung carcinoma xenografted in BALB/cByJ mice”, ONCOTARGET, 6(28), 25741-25754.
  • Y. C. Liu, Y. S. Li, S. Y. Lyu, L. J. Hsu, Y. H. Chen, Y. T. Huang, H. C. Chan, C. J. Huang, G. H. Chen, C. C. Chou, M. D. Tsai, T. L. Li*,2015,〈Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds〉,《NATURE CHEMICAL BIOLOGY》,11(5), 361-361。(SCIE) (IF: 12.587; SCIE ranking: 3.4%)
  • T. H. Huang, Y. H. Chiu, Y. L. Chan, Y. H. Chiu, H. Wang, K. C. Huang, T. L. Li, K. H. Hsu*, C. J. Wu* , 2015, “Prophylactic administration of fucoidan represses cancer metastasis by inhibiting vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) in Lewis tumor-bearing mice”, MARINE DRUGS, 13, 1882-1900. (SCIE) (IF: 4.073; SCIE ranking: 46.2%,84.8%)
  • H. Wang, T. L. Li, S. Hsia, I. L. Su, Y. L. Chan*, C. J. Wu*, 2015, “Skeletal muscle atrophy is attenuated in tumor-bearing mice under chemotherapy by treatment with fish oil and selenium”, ONCOTARGET, 6(10), 7758-7773.

Liang, Chi-Ming

  • Chen, T. A., Liao, C. C., Cheng, Y. C., Chen, Y. P., Hsu, Y. F., Liang C. M., Laing, S. M. , 2015, “Stimulation of Proliferation and Migration of Mouse Macrophages by Type B CpG-ODNs Is F-Spondin and IL-1Ra Dependent”, PLoS ONE, 10, e0128926. (SCIE) (IF: 2.74; SCIE ranking: 38%)
  • Ho, M. Y., Liang, C. M.*, Liang, S. M. , 2015, “MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis ”, Oncotarget, 6(1), 381-393.

Lin, Su-Chang

  • Lo YC*, Lin SC, Yang CY, Tung JY, 2015, “Tandem DEDs and CARDs suggest novel mechanisms of signaling complex assembly.”, Apoptosis : an international journal on programmed cell death, 20(2), 124-35. (SCIE) (IF: 4.543; SCIE ranking: 33.8%,25.3%)
  • Kao WP, Yang CY, Su TW, Wang YT, Lo YC*, Lin SC*, 2015, “The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-kappaB signaling.”, Apoptosis : an international journal on programmed cell death, 20(2), 174-95. (SCIE) (IF: 4.543; SCIE ranking: 33.8%,25.3%)

Ma, Che Alex

  • Lin CW, Tsai MH, Li ST, Tsai TI, Chu KC, Liu YC, Lai MY, Wu CY, Tseng YC, Shivatare SS, Wang CH, Chao P, Wang SY, Shih HW, Zeng YF, You TH, Liao JY, Tu YC, Lin YS, Chuang HY, Chen CL, Tsai CS, Huang CC, Lin NH, Ma C, Wu CY, Wong CH, 2015, “A common glycan structure on immunoglobulin G for enhancement of effector functions.”, Proceedings of the National Academy of Sciences of the United States of America, 112(34), 10611-6. (SCIE) (IF: 9.412; SCIE ranking: 11.3%)
  • Chen HS, Hou SC, Jian JW, Goh KS, Shen ST, Lee YC, You JJ, Peng HP, Kuo WC, Chen ST, Peng MC, Wang AH, Yu CM, Chen IC, Tung CP, Chen TH, Ping Chiu K, Ma C, Yuan Wu C, Lin SW, Yang AS, 2015, “Predominant structural configuration of natural antibody repertoires enables potent antibody responses against protein antigens.”, Scientific reports, 5, 12411. (SCIE) (IF: 3.998; SCIE ranking: 23.9%)
  • Wright JD., Chu HM, Huang CH, Ma C, Chang TW, Lim C, 2015, “Structural and Physical Basis for Anti-IgE Therapy”, Scientific Reports, 5(1), 11581. (SCIE) (IF: 3.998; SCIE ranking: 23.9%)
  • Wu HH, Hwang-Verslues WW, Lee WH, Huang CK, Wei PC, Chen CL, Shew JY, Lee EY, Jeng YM, Tien YW, Ma C, Lee WH, 2015, “Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines.”, The Journal of experimental medicine, 212(3), 333-349. (SCIE) (IF: 11.743; SCIE ranking: 5.7%,2.9%)

Wong, Chi-Huey

  • C.-W. Lin, M.-H. Tsai, S.-T. Li, T.-I. Tsai, K.-C. Chu, Y.-C. Liu, M.-Y. Lai, C.-Y. Wu, Y.-C. Tseng, S. S. Shivatare, C.-H. Wang, P. Chao, S.-Y. Wang, H.-W. Shih, Y.-F. Zeng, T.-H. You, J.-Y. Liao, Y.-C. Tu, Y.-S. Lin, H.-Y. Chuang, C.-L. Chen, C.-S. Tsai, C.-C. Huang, N.-H. Lin, C. Ma, C.-Y. Wu, and C.-H. Wong, 2015, “A common glycan structure on immunoglobulin G for enhancement of effector functions”, Proceedings of the National Academy of Sciences of the United States of America, 112(34), 10611-10616. (SCIE) (IF: 9.412; SCIE ranking: 11.3%)
  • C.-H. Wong, 2015, “Chemistry in Taiwan and Academia Sinica”, Angewandte Chemie-International Edition, 54(46), 13472-13473. (SCIE) (IF: 12.959; SCIE ranking: 8.5%)
  • X. Li, A. Kawamura, C. Andrews, J. Miller, D. Wu; M. Zhang, J. Huang, D. Oren, N. Padte, S. Porcelli, C.-H. Wong, S. Kappe, D. Ho, M. Tsuji, 2015, “Co-localization of a CD1d-binding glycolipid with malaria vaccines in LN-resident DCs for a robust adjuvant effect”, JOURNAL OF IMMUNOLOGY, 195(6), 2710-2721. (SCIE) (IF: 4.886; SCIE ranking: 28.3%)
  • S. Danishefsky, Y.-K. Shue, M. Chang, C.-H. Wong, 2015, “Development of Globo-H Cancer Vaccine”, Accounts of Chemical Research, 48(3), 643-652. (SCIE) (IF: 20.834; SCIE ranking: 4%)
  • H.-Y. Yen, Y.-C. Liu, N.-Y. Chen, C.-F. Tsai, Y.-T. Wang, Y.-J. Chen, T.-L. Hsu, P.-C.Yang, C.-H. Wong, 2015, “Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition”, Proceedings of the National Academy of Sciences of the United States of America, 112(22), 6955-6960. (SCIE) (IF: 9.412; SCIE ranking: 11.3%)
  • T.-W. Lin, H.-T. Chang, C.-H. Chen, C.-H. Chen, S.-W. Lin, T.-L. Hsu, C.-H. Wong, 2015, “Galectin-3 Binding Protein and Galectin-1 Interaction in Breast Cancer Cell Aggregation and Metastasis”, Journal of the American Chemical Society, 137(30), 9685-9693. (SCIE) (IF: 14.612; SCIE ranking: 7.3%)
  • J.-T. Chen, K.-L. Ku, C.-H. Chen, M. Hsiao, C.-P. Chiang, T.-L. Hsu, M.-H. Chen, and C.-H. Wong, 2015, “Glycoprotein B7-H3 overexpression and aberrant glycosylation in oral cancer and immune response”, Proceedings of the National Academy of Sciences of the United States of America, 112(42), 13057-13062. (SCIE) (IF: 9.412; SCIE ranking: 11.3%)
  • Y.-L. Huang, F.-S. Pai, Y.-T. Tsou, H.-C. Mon, T.-L. Hsu, C.-Y. Wu, T.-Y. Chou, W.-B. Yang, C.-H. Chen, C.-H. Wong, S.-L. Hsieh, 2015, “Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity”, The Journal of biological chemistry, 290(35), 21252-21263. (SCIE) (IF: 4.238; SCIE ranking: 29.3%)
  • Y.-Y. Ke, C.-H. Tsai, H.-M. Yu, Y.-C. Jao, J.-M. Fang, C.-H. Wong, 2015, “Latifolicinin A from a Fermented Soymilk Product and the Structure-Activity Relationship of Synthetic Analogues as Inhibitors of Breast Cancer Cell Growth”, Journal of agricultural and food chemistry, 63(44), 9715-9721. (SCIE) (IF: 4.192; SCIE ranking: 15.1%,6.9%,21.1%)
  • S. K. C. Cheung, P.-K. Chuang, H.-W. Huang, W. W. Hwang-Verslues, C. H.-H. Cho, W.-B. Yang, C.-N. Shen, M. Hsiao, T.-L. Hsu, C.-F. Chang, C.-H. Wong, 2015, “Stage-specific embryonic antigen-3 (SSEA-3) and beta3GalT5 are cancer specific and significant markers for breast cancer stem cells”, Proceedings of the National Academy of Sciences of the United States of America, 113(4), 960-965. (SCIE) (IF: 9.412; SCIE ranking: 11.3%)
  • C.-C. Tsai, C.-R. Lin, H.-Y. Tsai, C.-J. Chen, W.-T. Li, H.-M. Yu, Y.-Y. Ke, W.-Y. Hsieh, C.-Y. Chang, Y.-T. Wu, S.-T. Chen, C.-H. Wong, 2015, “The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling”, The Journal of biological chemistry, 290(19), 11935. (SCIE) (IF: 4.238; SCIE ranking: 29.3%)

Wu, Chung-Yi

  • Andrabi, R., Voss, J. E., Liang, C.-H., Briney, B., McCoy, L. E., Wu, C.-Y., Wong, C.-H., Poignard, P., Burton, D. R., 2015, “Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design”, IMMUNITY, 43, 959-973. (SCIE) (IF: 22.553; SCIE ranking: 1.3%)
  • CW Lin, MH Tsai, ST Li, TI Tsai, KC Chu, YC Liu, MY Lai, YC Tseng, CY Wu, SS Shivatare, CH Wang, P Chao, SY Wang, HW Shih, YF Zeng, TH You, JY Liao, CL Chen, CS Tsai, CC Huang, NH Lin, C Ma, CY Wu*, CH Wong*, 2015, “A common glycan structure on immunoglobulin G for enhancement of effector functions.”, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(34), 10611-10616. (SCIE) (IF: 9.412; SCIE ranking: 11.3%)
  • Huang YL, Pai FS, Tsou YT, Mon HC, Hsu TL, Wu CY, Chou TY, Yang WB, Chen CH, Wong CH, Hsieh SL*, 2015, “Human CLEC18 gene cluster contains C-type lectins with differential glycan-binding specificity.”, The Journal of biological chemistry, 290(35), 21252-21263. (SCIE) (IF: 4.238; SCIE ranking: 29.3%)
  • Liang, C.-H.; Hsu, C.-H.; Wu, C.-Y.*, 2015, “Sialoside Arrays: New Synthetic Strategies and Applications”, Topics in Current Chemistry, 367, 125-149. (SCIE) (IF: 7.455; SCIE ranking: 14.7%)

Yang, An-Suei

  • Chao-Ping Tung, Ing-Chien Chen, Chung-Ming Yu, Hung-Pin Peng, Jhih-Wei Jian, Shiou-Hwa Ma, Yu-Ching Lee, Jia-Tsrong Jan, An-Suei Yang*, 2015, “Discovering neutralizing antibodies targeting at the stem epitope of influenza hemagglutinin with synthetic phage-displayed antibody libraries”, Scientific Reports, 5, 15053. (SCIE) (IF: 3.998; SCIE ranking: 23.9%)
  • Chen, H.-S., S.-C. Hou, J.-W. Jian, K.-S. Goh, S.-T. Shen, Y.-C. Lee, J.-J. You, H.-P. Peng, W.-C. Kuo, S.-T. Chen, M.-C. Peng, H.-J. Wang, C.-M. Yu, I.-C. Chen, C.-P. Tung, T.-H. Chen, K. P. Chiu, C. Ma, C. Y. Wu, S.-W. Lin and A.-S. Yang*, 2015, “Predominant structural configuration in natural antibody repertoires enables potent antibody responses against protein antigens”, Scientific Reports, 5, 12411. (SCIE) (IF: 3.998; SCIE ranking: 23.9%)
  • Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, Joyce MG, Lingwood D, Soto C, Bailer RT, Ernandes MJ, Kong R, Longo NS, Louder MK, McKee K, O'Dell S, Schmidt SD, Tran L, Yang Z, Druz A, Luongo TS, Moquin S, Srivatsan S, Yang Y, Zhang B, Zheng A, Pancera M, Kirys T, Georgiev IS, Gindin T, Peng HP, Yang AS, Mullikin JC, Gray MD, Stamatatos L, Burton DR, Koff WC, Cohen MS, Haynes BF, Casazza JP, Connors M, Corti D, Lanzavecchia A, Sattentau QJ, Weiss RA, West AP Jr, Bjorkman PJ, Scheid JF, Nussenzweig MC, Shapiro L, Mascola JR, Kwong PD, 2015, “Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.”, Cell, 161, 1280-1292. (SCIE) (IF: 38.637; SCIE ranking: 1%,0.3%)