2004 and before


  • Chang, C.F. , Ho, C.W., Wu, C.Y., Chao, T.A., Wong, C.H. , and Lin, C.H. . Discovery of picomolar slow tight-binding inhibitors of alpha-fucosidase. Chem Biol 2004, 11, 1301-1306.
  • Chen, H.S., Tsai, Y.F., Lin, S., Lin, C.C. Khoo, K.H.Lin, C.H. , and Wong, C.H. . Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides. Bioorg Med Chem 2004, 12, 5595-5601.
  • Chen, J.H., Chang, Y.W., Yao, C.W., Chiueh, T.S., Huang, S.C., Chien, K.Y., Chen, A., Chang, F.Y., Wong, C.H. , and Chen, Y.J.. Plasma proteome of severe acute respiratory syndrome analyzed by two-dimensional gel electrophoresis and mass spectrometry. Proc Natl Acad Sci USA 2004, 101, 17039-17044.
  • Chien, C.M., Cheng, J.L., Chang, W.T., Tien, M.H., Tsao, C.M., Chang, Y.H., Chang, H.Y., Hsieh, J.F., Wong, C.H. , and Chen, S.T.. Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56(+) NK-cell cytotoxicity in cord blood. Bioorg Med Chem 2004, 12, 5603-5609.
  • Chou, C.H., Wu, C.S., Chen, C.H., Lu, L.D., Kulkarni, S.S., Wong, C.H. , and Hung, S.C.. Regioselective glycosylation of neamine core: a facile entry to kanamycin B related analogues. Org Lett 2004, 6, 585-588.
  • Chuang, T.J. , Chen, F.C., and Chou, M.Y.. A comparative method for identification of gene structures and alternatively spliced variants. Bioinformatics 2004, 20, 3064-3079.
  • Hsu, H.Y., Hua, K.F., Lin, C.C. Lin, C.H. , Hsu, J., and Wong, C.H. . Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways. J Immunol 2004, 173, 5989-5999.
  • Wu, C.Y., Jan, J.T., Ma, S.H., Kuo, C.J., Juan, H.F., Cheng, Y.S.E. , Hsu, H.H., Huang, H.C., Wu, D., Brik, A., Liang, F.S., Liu, R.S., Fang, J.M. , Chen, S.T., Liang, P.H. , and Wong, C.H. . Small molecules targeting severe acute respiratory syndrome human coronavirus. Proc Natl Acad Sci USA 2004, 101, 10012-10017.
  • Lester, L.B.; Kuo, H.C.; Andrews, L.; Nauert, B.; Wolf, D.P., Directed differentiation of rhesus monkey ES cells into pancreatic cell phenotypes. Reproductive Biology and Endocrinology2004 16;2(1):42-46


  • Nekrutenko, A., Chung, W.Y., and Li, W.H.. An evolutionary approach reveals a high protein-coding capacity of the human genome. Trends Genet 2003, 19, 306-310.
  • Nekrutenko, A., Chung, W.Y., and Li, W.H.. ETOPE: Evolutionary test of predicted exons. Nucleic Acids Res 2003, 31, 3564-3567.
  • Shih, A.C., and Li, W.H. . GS-Aligner: a novel tool for aligning genomic sequences using bit-level operations. Mol Biol Evol 2003, 20, 1299-1309.
  • Wu, C.Y., Chang, C.F. , Chen, J.S. , Wong, C.H. , and Lin, C.H. . Rapid diversity-oriented synthesis in microtiter plates for in situ screening: discovery of potent and selective alpha-fucosidase inhibitors. Angew Chem Int Ed Engl2003, 42, 4661-4664.