Chang, Chi-Fon

CFChang6x7Senior Research Specialist/Scientist


chifongateEmail
+886-2-27871236

 

EDUCATION AND POSITIONS HELD:

  • Ph.D. , Biophysics, The Ohio State University ,1997
  • Postdoctoral Fellow, Institute of Biomedical Sciences, Academia Sinica , 1997-1999
  • NMR Supporting Team Manager, Institute of Biomedical Sciences, Academia Sinica,1999-2002
  • NMR Facility Manager, High-Field Biomacromolecular Solution NMR Core Facility, Academia Sinica ,2002-present
  • Associate Research Specialist/Scientist, Genomics Research Center, Academia Sinica, 2004-2010
  • Senior Research Specialist/Scientist, Genomics Research Center, Academia Sinica, 2010-present

FACILITY MANAGEMENT / EXPERTISE:

As a research specialist, I am responsible for the daily operation on NMR facility and assist researchers carrying out NMR related researches. I have dedicated myself to provide competent and efficient routine service, as well as all aspects of advance technical support on NMR spectroscopy. The duty of my job includes: keeping track of machine time usage; supervising the facility staff members; training users on using NMR spectrometers; developing and implementing new NMR experiments; assisting users setting up advanced NMR experiments; advising users on specific NMR experiments and applications; and providing technical consultation. My expertise is using biophysical methods, especially the NMR approach, to obtain structural and functional information for biomolecules.

 NMR Facility
 GRC NMR Facility

SELECTED PUBLICATIONS:

  • Li Hao-Kai, Chang Chi-Fon, Lin Hsuan-Ju, Lin Jung-Lee, Lee Yu-Ting, Wu Yu-Hsuan, Liu Chiao-Yen, Lin Tze-Chia, Hsu Pang-Hung, Lin Hong-Ting Victor, 2021, “Conversion of a Thiol Precursor into Aroma Compound 4-mercapto-4-methyl-2-pentanone Using Microbial Cell Extracts”, Fermentation, 7(3), 129. (SCIE) (IF:  ;  )
  • Lin MH, Cho CC, Chiu YC, Chien CY, Huang YP, Chang CF, Hsu CH, 2021, “Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites.”, Communications biology, 4(1), 123. (SCIE)
  • Lin MH, Huang YP, Chang CF*, Hsu CH*, 2021, “NMR assignments of the macro domain from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).”, Biomolecular NMR assignments, 15(1), 137-142. (SCIE)
  • Maksimov EG, Laptev GY, Blokhin DS, Klochkov VV, Slonimskiy YB, Sluchanko NN, Friedrich T, Chang CF, Polshakov VI, 2021, “NMR resonance assignment and backbone dynamics of a C-terminal domain homolog of orange carotenoid protein.”, Biomolecular NMR assignments, 15(1), 17-23. (SCIE)
  • He KC, Chen YR, Liang CT, Huang SJ, Tzeng CY, Chang CF, Huang SJ, Huang HB, Lin TH, 2020, “Conformational Characterization of Native and L17A/F19A-Substituted Dutch-Type beta-Amyloid Peptides.”, International journal of molecular sciences, 21(7), 2571. (SCIE)
  • Lin MH, Yu TA, Chang CF, Nishikawa Y, Hsu CH, 2020, “NMR resonance assignments of the programmed cell death protein 5 (PDCD5) from Toxoplasma gondii.”, Biomolecular NMR assignments, 14(2), 277-280. (SCIE)
  • Mariasina SS, Chang CF, Petrova OA, Efimov SV, Klochkov VV, Kechko OI, Mitkevich VA, Sergiev PV, Dontsova OA, Polshakov VI, 2020, “Williams-Beuren syndrome-related methyltransferase WBSCR27: cofactor binding and cleavage.”, The FEBS journal, 287(24), 5375-5393. (SCIE)
  • Hsu NS, Wang YL, Lin KH, Chang CF, Ke SC, Lyu SY, Hsu LJ, Li YS, Chen SC, Wang KC, Li TL, 2018, “Evidence of Diradicals Involved in the Yeast Transketolase Catalyzed Keto-Transferring Reactions.”, Chembiochem : a European journal of chemical biology, 19(22), 2395-2402. (SCIE)
  • Liang CT, Lin YS, Huang YC, Huang HL, Yang JQ, Wu TH, Chang CF, Huang SJ, Huang HB, Lin TH, 2018, “Characterization of the interactions between inhibitor-1 and recombinant PP1 by NMR spectroscopy.”, Scientific reports, 8(1), 50. (SCIE)
  • Mariasina SS, Petrova OA, Osterman IA, Sergeeva OV, Efimov SV, Klochkov VV, Sergiev PV, Dontsova OA, Huang TH, Chang CF*, Polshakov VI*, 2018, “NMR assignments of the WBSCR27 protein related to Williams-Beuren syndrome.”, Biomolecular NMR assignments, 12(2), 303-308. (SCIE)
  • Hsu Chen, Wu Bo-Yuan, Chang Yu-Chuan, Chang Chi-Fon, Chiou Tai-Ying, Su Nan-Wei, 2018, “Phosphorylation of Isoflavones by Bacillus subtilis BCRC 80517 May Represent Xenobiotic Metabolism”, Journal of Agricultural and Food Chemistry, 66(1), 127-137. (SCIE)
  • Li TL, Hsu NS, Wang YL, Lin KH, Chang CF, Lyu SY, Hsu LJ, Liu YC, Chang CY, Wu CJ, 2018, “The Mesomeric Effect of Thiazolium on non-Kekule Diradicals in Pichia stipitis Transketolase”, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 57(7), 1802-1807. (SCIE)
  • Lin Tien-Wei, Chang Chi-Fon, Chang Yu-Jen, Liao Yi-Hung, Yu Hui-Ming, Chen Yun-Ru, 2017, “Alzheimer’s amyloid-β A2T variant and its N-terminal peptides inhibit amyloid-β fibrillization and rescue the induced cytotoxicity”, PLOS ONE, 12(3), e0174561. (SCIE)
  • Chi-Fon Chang, Chung-ke Chang, Hsin-Yun Sun, Yee-Chun Chen, 2016, “High-Field NMR-Based Metabolomics Studies of Human and Bacteria Specimens of Clinical Interest”, paper presented at The XXVIIth International Conference on Magnetic Resonance in Biological Systems, Kyoto, Japan: ICMRBS, 2016-08-21 ~ 2016-08-26.
  • Chou CY, Chu M, Chang CF, Yu T, Huang TH, Sakellariou D, 2016, “High sensitivity high-resolution full range relaxometry using a fast mechanical sample shuttling device and a cryo-probe.”, Journal of biomolecular NMR, 66(3), 187-194. (SCIE)
  • Liang CT, Huang HB, Wang CC, Chen YR, Chang CF, Shiao MS, Chen YC, Lin TH, 2016, “L17A/F19A Substitutions Augment the alpha-Helicity of beta-Amyloid Peptide Discordant Segment.”, PloS one, 11(4), e0154327. (SCIE)
  • Huang YP, Cho CC, Chang CF*, Hsu CH*, 2016, “NMR assignments of the macro domain from Middle East respiratory syndrome coronavirus (MERS-CoV).”, Biomolecular NMR assignments, 10(2), 245-248. (SCIE)
  • Polshakov VI1*, Eliseev BD, Frolova LY, Chang CF, Huang TH, 2015, “Backbone 1H, 13C and 15N resonance assignments of the human eukaryotic release factor eRF1”, Biomolecular NMR Assignment, 9(1), 37-42. (SCIE)
  • Chi-Jen Lo, Chia-Lin Chyan, Yi-Chen Chen, Chi-Fon Chang, Hsien-bin Huang, Ta-Hsien Lin , 2015, “Resonance assignments and secondary structure of apolipoprotein E C-terminal domain in DHPC micelles.”, Biomolecular NMR assignments, 9(1), 187-190. (SCIE)
  • Chi-Jen Lo, Chih-Ching Wang, Hsien-Bin Huang, Chi-Fon Chang, Ming-Shi Shiao, Yi-Cheng Chen, Ta-Hsien Lin*, 2015, “The Arctic mutation accelerates Abeta aggregation in SDS through reducing the helical propensity of residues 15-25.”, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 22(1), 8-18. (SCIE)
  • Sabater Laurent, Fang Pei-Ju, Chang Chi-Fon, De Rache Aurore, Prado Enora, Dejeu Jérôme, Garofalo Antonio, Lin Jung-Hsin, Mergny Jean-Louis, Defrancq Eric, Pratviel Geneviève, 2015, “Cobalt(iii)porphyrin to target G-quadruplex DNA”, Dalton Transactions, 44(8), 3701-3707. (SCIE)
  • Hsu CH, Chang CF, Liao YD, Wu SH, Chen C, 2015, “Solution structure and base specificity of cytotoxic RC-RNase 2 from Rana catesbeiana.”, Archives of biochemistry and biophysics, 584, 70-8. (SCIE)
  • Huang SY, Chang CF, Fang PJ, Naik MT, Guntert P, Shih HM, Huang TH*, 2015, “The RING domain of human promyelocytic leukemia protein (PML).”, Journal of biomolecular NMR, 61(2), 173-80. (SCIE)
  • Wang YS, Ko CH, Chang HT, Yang KJ, Chen YJ, Huang SJ, Fang PJ, Chang CF, Tzou DL.*, 2014, “1H, 13C and 15N backbone and side-chain resonance assignments of a family 36 carbohydrate binding module of xylanase from Paenibacillus campinasensis.”, Biomol NMR Assignment, 8(2),303-306. (SCIE)
  • Kung CC, Naik MT, Wang SH, Shih HM, Chang CC, Lin LY, Chen CL, Ma C, Chang CF, Huang TH., 2014, “Structural Analysis of poly-SUMO Chain Recognition by RNF4-SIMs Domain.”, BIOCHEMICAL JOURNAL, 462, 53-65. (SCIE)
  • Chung-ke Chang, Ming-Hon Hou, Chi-Fon Chang, Chwan-Deng Hsiao, Tai-huang Huang*, 2014, “The SARS coronavirus nucleocapsid protein – Forms and functions”, ANTIVIRAL RESEARCH, 103, 39-50. (SCIE)
  • Lee AY, Chen YD, Chang YY, Lin YC, Chang CF, Huang SJ, Wu SH, Hsu CH, 2014, “Structural basis for DNA-mediated allosteric regulation facilitated by the AAA+ module of Lon protease.”, Acta crystallographica. Section D, Biological crystallography, 70(Pt 2), 218-30.
  • Li YC, Chang CK, Chang CF, Cheng YH, Fang PJ, Yu T, Chen SC, Li YC, Hsiao CD, Huang TH, 2014, “Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element.”, Nucleic acids research, 42(13), 8777-88. (SCIE)
  • Huang SY, Naik MT, Chang CF, Fang PJ, Wang YH, Shih HM, Huang TH, 2014, “The B-box 1 dimer of human promyelocytic leukemia protein.”, Journal of biomolecular NMR, 60(4), 275-81. (SCIE)
  • Ming-Yuan Su, Chung-I Chang and Chi-Fon Chang* , 2013, “1H, 13C and 15N resonance assignments of the pyrin domain from human PYNOD ”, Biomolecular NMR Assignments, 7(2), 141-143. (SCIE)
  • Ming-Yuan Su, Chiao-I Kuo, Chi-Fon Chang*, Chung-I Chang*, 2013, “Three-Dimensional Structure of Human NLRP10/PYNOD Pyrin Domain Reveals a Homotypic Interaction Site Distinct from Its Mouse Homologue”, PLoS One, 8(7), e67843. (SCIE)
  • Chen Hsu, Hsiao-Wen Ho, Chi-Fon Chang, Shang-Ta Wang, Ting-Fang Fang, Min-Hsiung Lee, Nan-Wei Su*, 2013, “Soy isoflavone-phosphate conjugates derived by cultivating Bacillus subtilis var. natto BCRC 80517 with isoflavone ”, FOOD RESEARCH INTERNATIONAL, 53(1), 487-495. (SCIE)
  • Chang CK, Chiang MH, Toh EK, Chang CF, Huang TH*, 2013, “Molecular mechanism of oxidation-induced TDP-43 RRM1 aggregation and loss of function”, FEBS LETTERS, 587(6), 575-582. (SCIE)
  • Ariesandi W, Chang CF, Chen TE, Chen YR*, 2013, “Temperature-dependent structural changes of Parkinson\'s alpha-synuclein reveal the role of pre-existing oligomers in alpha-synuclein fibrillization.”, PloS one, 8(1), e53487. (SCIE)
  • Chun-Hua Hsu* , Tang-Long Shen, Chi-Fon Chang, Yu-Yung Chang, Lin-Ya Huang , 2012, “Solution Structure of the Oncogenic MIEN1 Protein Reveals a Thioredoxin-Like Fold with a Redox-Active Motif”, PLoS One, 7(12), e52292. (SCIE)
  • Ching-Yu Chou, Chi-Fon Chang, Tai-Huang Huang*, 2012, “NMR Field Cycling Approach : A compact high-speed mechanical design and its application”, paper presented at XXVth International Council on Magnetic Resonance in Biological Systems, Lyon Convention Centre, Lyon, France: Institut Pasteur - CNRS, Paris, France, 2012-08-19 ~ 2012-08-24.
  • Sheng-Chia Chen, Chi-Fon Chang, Pei-Ju Fan, Ya-Hsin Cheng,Tsunai Yu, Tai-huang Huang, 2012, “1H, 13C and 15N resonance assignments of the C-terminal DNA-binding domain of RstA protein from Klebsiella pneumoniae”, Biomolecular NMR Assignments, 7(1), 85-88. (SCIE)
  • Chou CY, Chu M, Chang CF, Huang TH*, 2012, “A compact high-speed mechanical sample shuttle for field-dependent high-resolution solution NMR.”, Journal of magnetic resonance (San Diego, Calif. : 1997), 214(1), 302-8.
  • Ingjye Jiang, Chen-Kun Tsai, Sheng-Chia Chen, Szu-huan Wang, Imamaddin Amiraslanov, Chi-Fon Chang, Wen-Jin Wu, Jung-Hsiang Tai, Yen-Chywan Liaw*, Tai-huang Huang*, 2011, “Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis”, NUCLEIC ACIDS RESEARCH, 39(20), 8992-9008. (SCIE)
  • Chun-Jiun Yang, Chi-Fon Chang*, Lin-Ya Huang, Yu-Yung Chang, Tang-Long Shen,Chun-Hua Hsu*, 2010, “Resonance assignments of human C35 (C17orf37) protein, a novel tumor biomarker”, Biomolecular NMR Assignments, 4(2), 191-193. (SCIE)
  • Ching-Yu Chou, Chi-Fon Chang, Tai-Huang Huang, 2010, “NMR Field Cycling Approach to Biomolecular Dynamics”, paper presented at XXIVth International Conference on Magnetic Resonance in Biological Systems, Cairns, Australia: International Conference on Magnetic Resonance in Biological Systems, 2010-08-22 ~ 2010-08-27.
  • Ni-Shian Lin, John Ching-Hao Chao, Fang-Chieh Chou, Chi-Fon Chang, Yun-Ru Chen, Yu-Jen Chang, Shing-Jong Huang, Wei-Hsiang Tseng, Jerry C. C. Chan*, 2010, “Molecular Structure of Amyloid Fibrils Formed by Residues 127 to 147 of the Human Prion Protein”, CHEMISTRY-A EUROPEAN JOURNAL, 16(18), 5492-5499. (SCIE)
  • Tai-huang Huang*, Chi-Fon Chang, Wen-Jen Wu, 2009, “Applications of Taiwan Ultra High-Field Solution NMR in Genomics Medicine”, Instrument Today, 172, 110-115.
  • Ching-Yu Chou, Chi-Fon Chang, Tai-huang Huang*, 2009, “Shuttling Device for Field Cycling Experiment on NMR Relaxation Study in Biological Systems”, paper presented at The 3rd Asia-Pacific NMR Symposium, Ramada Plaza Jeju Hotel, Jeju Island: Korean Magnetic Resonance Society, 2009-10-25 ~ 2990-10-28.
  • Hung-Ju Chang, Hung-Ju Hsu, Chi-Fon Chang, Hung-Pin Peng, Yi-Kun Sun, Hui-Ming Yu, Hsi-Chang Shih, Chun-Ying Song, Yi-Ting Lin, Chu-Chun Chen, Chia-Hung Wang, An-Suei Yang, 2009, “Molecular evolution of cystine-stabilized miniproteins as stable proteinaceous binders.”, Structure, 17(4), 620-631. (SCIE)
  • C. F. Chang*,2008,〈Introduction to methods for fast multidimensional NMR〉,《Chemistry》,66(3), 199。
  • C.-F. Chang, P.-J. Fang, T-A. Yu, D. T. Chuang, T.-h. Huang, 2008, “NMR studies of interaction between E2 and E1/E3 components in human branched-chain a-ketoacid dehydrogenase complex”, P476,244 pages, paper presented at XXIIIrd International Conference on Magnetic Resonance in Biology Systems, San Diego, CA, USA: ICMRBS, 2008-08-24 ~ 2008-08-29.
  • Naik MT, Chang CF, Kuo IC, Kung CC, Yi FC, Chua KY, Huang TH, 2008, “Roles of structure and structural dynamics in the antibody recognition of the allergen proteins: an NMR study on Blomia tropicalis major allergen.”, Structure (London, England : 1993), 16(1), 125-36.
  • M. T. Naik, C. F. Chang, I. C. Kuo, T. Yu, P. J. Fang, K. Y. Chua and T. H. Huang, 2007, “Complete H-1, C-13 and N-15 resonance assignments of Blo t 5, a major mite allergen from Blomia tropicalis”, J Biomol NMR, 38(2), 189-189. (SCIE)
  • K. W. Hung, Y. C. Lin, C. C. Cheng, P. J. Fang, C. F. Chang, S. F. Tasi and T. H. Huang, 2006, “Resonance assignments of a CoA binding protein from Klebsiella pneumoniae”, J Biomol NMR, 36 Suppl 1, 74. (SCIE)
  • C.-F. Chang, T.-A. Yu, H.-T. Chou, D. T. Chuang, T.-h. Huang, 2006, “Studies of Protein Domains in the Transacylase Component of Human Mitochondrial Branched-Chain Ketoacide Dehydrogenase”, PP50,118 pages, paper presented at The 11th Symposium on Recent Advances in Biophysics, Taipei, Taiwan: Biophysics Society of R.O.C., 2006-05-24 ~ 2006-05-26.
  • C. F. Chang*, F. K. Shi and Y. Y. Wu, 2006, “Introduction of Recent Advance in NMR Technology and Application”, Instrument Today, 27, 61-67.
  • K. P. Wu, J. M. Chang, J. B. Chen, C. F. Chang, W. J. Wu, T. H. Huang, T. Y. Sung and W. L. Hsu, 2006, “RIBRA - An Error-Tolerant Algorithm for the NMR Backbone Assignment Problem”, J Comput Biol, 13, 229-244. (SCIE)
  • Chang CF, Chou HT, Lin YJ, Lee SJ, Chuang JL, Chuang DT, Huang TH, 2006, “Structure of the subunit binding domain and dynamics of the di-domain region from the core of human branched chain alpha-ketoacid dehydrogenase complex.”, The Journal of biological chemistry, 281(38), 28345-53. (SCIE)
  • C.-F. Chang, Y.-J. Lin, H.-T. Chou, M. Wynn, D. T. Chuang, T.-h Huang, 2005, “Studies of Protein Domains in the Transacylase Component of Human Mitochondrial Branched-Chain Ketoacide Dehydrogenase”, AP59,159 pages, paper presented at The 1st Asia-Pacific NMR Symposium, Yokohama, Japan: The NMR Society of Japan, 2005-11-08 ~ 2005-11-11.
  • Mahajan, A., Yuan, C., Pike, B. L., Heierhorst, J., Chang, C. F. and Tsai, M. D., 2005, “FHA domain-ligand interactions: importance of integrating chemical and biological approaches.”, J Am Chem Soc, 127(42), 14572-14573. (SCIE)
  • Chang, C. K., Sue, S. C., Yu, T. H., Hsieh, C. M., Tsai, C. K., Chiang, Y. C., Lee, S. J., Hsiao, H. H., Wu, W. J., Chang, C. F. and Huang, T. H., 2005, “The dimer interface of the SARS coronavirus nucleocapsid protein adapts a porcine respiratory and reproductive syndrome virus-like structure.”, FEBS Lett, 579(25), 5663-5668. (SCIE)
  • Kouza, M., Chang, C. F., Hayryan, S., Yu, T. H., Li, M. S., Huang, T. H. and Hu, C. K., 2005, “Folding of the Protein Domain hbSBD.”, Biophys J, 89(5), 3353-3361. (SCIE)
  • S. C. Sue, C. F. Chang, Y. T. Huang, C. Y. Chou and T. H. Huang, 2005, “Challenges in NMR-based structural genomics”, Physica A, 350, 12-27. (SCIE)
  • C.-F. Chang, Y.-J. Lin, H.-T. Chou, S.-J. Lee, D. T. Chuang, and T.-h. Huang, 2005, “Structure and Dynamics Characterization of Protein Domains in the Transacylase Component of Human Mitochondrial Branched-Chain alpha-Ketoacid Dehydrogenase”, P93, 140 pages, paper presented at XXI International Conference on Magnetic Resonance in Biology Systems, Hyderabad, India: ICMRBS, 2005-01-16 ~ 2005-01-21.
  • V. Y. Gorbatyuk, C. K. Tsai, C. F. Chang and T. H. Huang, 2004, “Effect of N-terminal and Met23 mutations on the structure and dynamics of onconase”, J Biol Chem, 279, 5772-5780. (SCIE)
  • S. I. Tyukhtenko, Y. T. Huang, T. H. Lin, C. P. Chen, C. F. Chang, S. J. Lee, A. V. Litvinchuk, J. F. Shaw, Y. C. Liaw and T. H. Huang, 2004, “Probing the Enzyme Catalytic Mechanism by Nuclear Magnetic Resonance - A Case Study of a Serine Protease”, Journal of the Chinese Chemical Society, 51, 1133-1140. (SCIE)
  • C.-F. Chang, S.-J. Lee, Y.-J. Lin, B.-N. Chen, T.-h. Huang, 2003, “Structure and Backbone Dynamics of Proteins from transacylase component of Human Mitochondrial Branched-Chain alpha-Ketoacid Dehydrogenase”, PS05 pages, paper presented at Forth East Asian Biophysics Symposium, Taipei, Taiwan: Biophysics Society of R.O.C., 2003-11-03 ~ 2003-11-06.
  • S. I. Tyukhtenko, A. V. Litvinchuk, C. F. Chang, Y. C. Lo, S. J. Lee, J. F. Shaw, Y. C. Liaw and T. H. Huang, 2003, “Sequential structural changes of Escherichia coli thioesterase/protease I in the serial formation of Michaelis and tetrahedral complexes with diethyl p-nitrophenyl phosphate”, Biochemistry, 42, 8289-8297. (SCIE)
  • C.-F. Chang, H.-T. Chou, J. L. Chuang, D.T. Chuang, T.-h. Huang, 2002, “Structure and Backbone Dynamics of a Lipoyl Domain from Human Mitochondrial Branched-Chain alpha-Ketoacid Dehydrogenase”, PL356, 221 pages, paper presented at XXth International Conference on Magnetic Resonance in Biology Systems, Toronto, Canada: ICMRBS, 2002-08-25 ~ 2002-08-30.
  • C.-F. Chang, H.-T. Chou, J. L. chuang, D. T. Chuang, T.-h. Huang, 2002, “Solution Structure and Dynamics of the Lipoic Acid-bearing Domain of Human Mitochondrial Branched-Chain alpha-Ketoacid Dehydrogenase Complex”, 48 pages, paper presented at The 8th Symposium on Recent Advances in Biophysics, Academia Sinica, Taiwan: Biophysics Soceity of R.O.C., 2002-05-22 ~ 2002-05-25.
  • S. I. Tyukhtenko, A. V. Litvinchuk, C. F. Chang, R. J. Leu, J. F. Shaw and T. H. Huang, 2002, “NMR studies of the hydrogen bonds involving the catalytic triad of Escherichia coli thioesterase/protease I”, FEBS Lett, 528, 203-206. (SCIE)
  • Chang CF, Chou HT, Chuang JL, Chuang DT, Huang TH, 2002, “Solution structure and dynamics of the lipoic acid-bearing domain of human mitochondrial branched-chain alpha-keto acid dehydrogenase complex.”, The Journal of biological chemistry, 277(18), 15865-73. (SCIE)
  • C.-F. Chang, H.-T. Chou, J. L. Chuang, D.T. Chuang,T.-h. Huang, 2001, “Solution structure of the lipoic acid-bearing domain of human mitochondrial branched-chain alpha-ketoacid dehydrogenase”, POS9-A-16 pages, paper presented at The 9th SCBA International Symposium, Academia Sinica, Taiwan: SCBA, 2001-08-05 ~ 2001-08-10.
  • C.-F. Chang, H.-T. Chou, O. Gorbatyuk, J. Chuang, D. Chaung, T.-h. Huang, 2001, “The Solution Structure of the Lipoic Acid-bearing Domain of Human Mitochondrial Branched-Chain alpha-Ketoacid Dehydrogenase Complex”, P02, 52 pages, paper presented at The 7th Symposium on Recent Advance in Biophysics, Taipei, Taiwan: Biophysics Soceity of R.O.C., 2001-05-23 ~ 2001-05-26.
  • N. Y. Su, Y. D. Liao, C. F. Chang, I. Wanga and C. Chen*, 2001, “1H, 15N and 13C resonance assignments and secondary structure of the liver ribonuclease from bullfrog Rana catesbeiana”, J Biomol NMR, 20, 189-190. (SCIE)
  • S. I. Tyukhtenko, A. V. Litvinchuk,C.-F. Chang,T.-h. Huang, 2000, “NMR Detection and Characterization of Strong Hydrogen Bonds in the Catalytic Triad of E. coli Thioesterase/protease I”, M&T P052 pages, paper presented at The 42nd Experimental Nuclear Magnetic Resonance Conference, Pacific Grove, California, USA: ENC, 2000-04-09 ~ 2000-04-14.
  • C.-F. Chang, C. Chen, Y.-C. Chen, Y. Wu, K. Hom, T.-h Huang, 1998, “Structure and Function of Cell cytotoxic Ribonuclease by NMR Spectroscopy”, 86 pages, paper presented at 1998 Fall Camp, Enzymes: Function and Structure, Taiwan: The Society for Biochemistry and Molecualr Biology, Taiwan, 1998-10-30 ~ 1998-11-01.
  • C.-F. Chang, C. Chen, Y.-C. Chen, K. Hom, R.-F. Huang,T.-h. Huang, 1998, “Solution Structure and binding studies of RC-RNase by 1H NMR Spectroscopy”, paper presented at XVIIIth International Conference on Magnetic Resonance in Biology Systems, Tokyo, Japan: ICMRBS, 1998-08-23 ~ 1998-08-28.
  • C.-F. Chang, C. Chen, Y.-C. Chen, K. Hom, R.F. Huang,T.-h Huang, 1998, “Solution Structure of the Complexs of RC-RNase with 2',5'-CpG and 3',5'-d(CpG)”, S27 pages, paper presented at The 4th Symposium on Recent Advances in Biophysics, Taipei, Taiwan: Biophysics Society of R.O.C., 1998-05-13 ~ 1998-05-16.
  • C. F. Chang, M. H. Zehfus, 1998, “Effects of backbone modification on helical peptides: the reduced carbonyl modification”, Biopolymers, 46, 181-193. (SCIE)
  • C. F. Chang, C. Chen, Y. C. Chen, K. Hom, R. F. Huang and T. H. Huang, 1998, “The solution structure of a cytotoxic ribonuclease from the oocytes of Rana catesbeiana (bullfrog)”, J Mol Biol, 283, 231-244. (SCIE)
  • C.-F. Chang,M. H. Zehufs, 1997, “The Effect of Peptide Backbone Modification on Helix Structure”, paper presented at Biophysical Society Annual Meeting, New Orleans, Louisiana, USA: Biophysical Society, 1997-02-01 ~ 1997-02-06.
  • C.-F. Chang,M. H. Zehfus, 1996, “The Effect of N-Methyl Isosteres on Helical Peptides”, paper presented at Protein Science Society Meeting, LA, USA: Protein Science Society, 1996-06-07 ~ 1996-06-14.
  • C. F. Chang, M. H. Zehfus, 1996, “Effects of N-Methyl Isosteres on Helix Stability”, In: Peptides: Chemistry, Structure and Bioloby, 531, (?).
  • C. F. Chang, M. H. Zehfus, 1996, “The Effect of N-Methylation on Helical Peptides”, Biopolymers, 40, 609-616. (SCIE)
  • C.-F. Chang,M.H. Zehfus, 1995, “Effects of N-Methyl Isosters on Helix Stability”, paper presented at 14th American Peptide Symposium, Columbus OH, USA: The Ohio State University, USA, 1995.
  • Chang, C. F.; Hwang, L. P, 1991, “Relaxation Studies of 2IzSz Spin Order in Liquid Benzene:Selection of Chemical Shift Anisotropy Parameters”, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 38, 1-4. (SCIE)