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Simplified Procedure to Prepare Remdesivir for SARS-CoV-2 and Nipah Virus
After grappling with the corona virus, SARS-CoV-2, for more than a year, the world is still being haunt-ed by Covid-19. Remdesivir is the first drug approved by the US Food and Drug Administration (FDA) to treat Covid-19. In May 2020, Taiwanese authority also approved the use of remdesivir in patients with severe COVID-19 symptoms. In reality, that price tag is still a price too much to pay for many people. Read More
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NMR: An essential tool to explore biological mysteries at the molecular level
Nuclear magnetic resonance(NMR) is a widely used analytical technique, it has become an essential tool when studying physics, chemistry, materials, and life sciences. With NMR, scientists can dig into the molecular level of a matter to dissect its chemical constructs. Let's see how researchers in Genome Research Center and other Institutes are doing with NMR to leverage their research work in solving the mysteries of the biological matters. Read More
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Pancreatic Cancer Cell Escaping Blueprint Brings Hope to Ease Metastasis
Pancreatic cancer is known to be vicious, pancreatic ductal adenocarcinoma (PDAC) is the type that ac-counts for 95% of pancreatic cancer and so far it is still incurable. An added fact makes PDAC doomed lies in its tendency to have metastasis, meaning cancer cells have already spread to other organs, when diagnosed. Read More
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DSG2 Controls Breast Cancer Metastasis
Breast cancer has been the most common cancer in women worldwide. Even though early detection and therapeutic strategies have made breast cancer less life-threatening and increased the 5-year survival rate to more than 90%, the survival rate is still only 30% for later stage breast cancers that have metastasized. Professor Wendy W. Hwang-Verslues discovered that expression of Desmoglein2 ... Read More
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Repurposing Existing Medicines as Anti-COVID-19 Virus Agents
SARS-CoV-2 definitely dominates the worldwide attention in year 2020, the pandemic has taken more human lives than many other major historical pandemics, and it does not have a sign to be under control yet. In February 2020, while it was still unfamiliar to many parts of the world and did not have an official name, professor Chi-Huy Wong had publicly acknowledged... Read More
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Achievements of The Summit Translational Program (2006-2020)
Since outbreak of Severe Acute Respiratory Syndrome (SARS) in 2003, our society recognized the need to establish translational biomedical research for emerging infectious diseases and other major diseases in Taiwan. Dr. Chi-Huey Wong was invited in 2003 by Former President Yuan-Tseh Lee of Academia Sinica (AS) as the founding Director of Genomic Research Center ... Read More
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LATEST PUBLICATIONS
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Practical Remdesivir Synthesis through One-Pot Organo-Catalyzed Asymmetric (S)-P-Phosphoramidation
Shang-Cheng Hung, Chi-Huey Wong
JOC
February 26, 2021 -
Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
Che Ma, Shang-Cheng Hung, Chi-Huey Wong
PNAS
February 02, 2021
HONORS & APPOINTMENTS
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Congratulations to Dr. Shie-Liang Hsieh for receiving the MOST 2020 Outstanding Researcher AwardRead More
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Portable Liquid Chromatography Mass Spectrometer wins the Chen’s Team the IBMI Award -
Patient-Derived Tumor Organoid Platform and Cell Bankfor Cancer Precision Medicine wins the Chang’s Team the IBMI Award
Research in GRC Series
Seminars & Events
