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The Next Chapter of Precision Chemical Modification: From Natural Product Inspirations to Efficient Drugs for Rare Disease
"Natural is Still the Best!" Scientists have isolated numerous small molecules with potential biological activity from natural sources. However, these molecules often require chemical modifications and structural refinements to unleash their full potential. Read More
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Prof. Shang-Cheng Hung awarded 2024 Mizutani Foundation for Glycoscience Research Grant
The research in Dr. Hung’s group aims on the development of novel methodologies for the synthesis of biologically potent oligosaccharides, glycolipids, and glycoproteins via a combination of regioselective one-pot... Read More
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Dr. Che Alex Ma awarded the Ho Chin-Tui Award (Basic Science-Biology)
This award recognizes Dr. Ma’s significant contribution for discovering the broad protection of a low-sugar spike protein vaccine against new coronavirus variants and identifying a lectin in Lablab extract effective against various influenza and coronavirus strains. Read More
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Sulfated Disaccharides Repair Toxic Protein Gain-of-Function, a New Approach to Treatment of Amyotrophic Lateral Sclerosis
Although ALS and FTD differ in clinical symptoms, they share many pathological features and genetic variations. The most common genetic mutation for both diseases originates from hexanucleotide repeat expansion of the GGGGCC (G4C2) sequence in the non-coding region of the C9ORF72 gene. Read More
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Dr. Tsung-Lin Li awarded the 2023 NSTC Outstanding Research Award
Dr. Li has long dedicated to the specialty of natural products biosynthesis, antibiotics development, and structural mechanistic design of biocatalysts. His most recent finding is a non-canonical FAD-dependent enzyme... Read More
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Dr. Yun-Yu (Ruby) Chen awarded Boehringer Ingelheim’s Biomedicine Innovation Program
In recognition of Dr. Yun-Ru (Ruby) Chen's contributions to the development of specific and unique humanized structural monoclonal antibodies, which bring hope to the treatment of neurodegenerative and pathological diseases. Read More
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語言
LATEST PUBLICATIONS
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Sulfated disaccharide protects membrane and DNA damages from arginine-rich dipeptide repeats in ALS
Yun-Ru (Ruby) Chen
Science Advances
February 23, 2024 -
Mechanistic Insights into Dibasic Iminosugars as pH-Selective Pharmacological Chaperones to Stabilize Human α-Galactosidase
Wei-Chieh Cheng
JACS Au
February 23, 2024 -
Synthesis and Quantitative Analysis of Glycans Conjugated to Gold Nanoparticles
Chi-Huey Wong
Helvetica Chimica Acta
February 20, 2024
HONORS & APPOINTMENTS
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Recognition of Excellence: 2023 Postdoctoral Researcher Academic Research Award by the National Science and Technology CouncilRead More
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Congratulations to Dr. Yi-Chung Hsieh for winning Distinguished Thesis Awards of the 19th TienTe Lee Biomedical AwardsRead More
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Congratulations to Nguyen Hong Thuy Vy for winning the Distinguished Thesis Award of the 33rd Wang Ming-Ning Award!Read More
Research in GRC Series
Research News
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- PopularScience
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Making the right tools for tough jobs – how to build a scientific instrument / Dr. Yi-Sheng WangRead More
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Scientific Fortune Telling: Predicting Risk of Liver Cancer for Patients with Chronic Hepatitis B / Dr. Hwai-I Yang / 2013Read More
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Unveiling Antigen Presentation and Cross-reactive Antibody Response of an Oligosaccharide-conjugate Vaccine, Paving the Way for Advanced Cancer VaccinesRead More
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