課程師資

Pr. Yi-Hsiang Hsu is the Co-Director of the GeriOMICS Center, HSL Institute for Aging Research, Beth Israel Deaconess Medical Center, Boston, MA. He is an Assistant Professor at Harvard Medical School and at Program for Quantitative Genomics, Program of Molecular and Integrative Physiological Sciences, Harvard School of Public Health, Boston, MA. He is also an Associate Faculty Member at the BROAD Institute of MIT and Harvard, Cambridge, MA.

Dr. Hsu is a Statistical Geneticist/Computational Biologist. His research focuses on (1) Genetic contribution of common aging relevant disorders (such as osteoporosis, sarcopenic obesity, metabolic syndrome, type 2 diabetes and hypertension) using population-based next generation (NGS) whole genome sequencing, exome-sequencing and genome-wide association (GWAS) approaches to identify common and rare variants that are associated with these complex traits/phenotypes; (2) Predicting non-coding causal variants and targeted genes in GWAS loci using tissue-and cell-specific gene regulatory landscapes generated by ENCODE and US NIH Roadmap Epigenomics Project;   (3) Statistical method development on multiple-phenotype association analyses; (4) Integrating omics data (genomics, transcriptome, epigenomics, proteomics and metabolomics) using system genetics and bioinfomatic approaches; and (4) Identifying biomarkers of osteoporosis using metabolomics.

Dr. Yaoyu Wang is Associate Director of the Center for Cancer Computational Biology at the Dana-Farber Cancer Institute.  He received his B.S. in Biological Science and Computer Science from the Carnegie-Mellon University, and his Ph.D in Bioinformatics from the Boston University.  He was a postdoctoral fellow in virology and immunology at the Ragon Institute of MGH, MIT, and Harvard.

He currently leads the Center for Cancer Computational Biology (CCCB; http://cccb.dfci.harvard.edu), which focuses on developing and providing Next Generation Sequencing technology and bioinformatics as research resources to community.

Dr. Chia-Yen Chen is a postdoctoral research fellow at the Psychiatric and Neurodevelopmental Genetics Unit (PNGU) and the Analytic and Translational Genetics Unit (ATGU) at Massachusetts General Hospital. Dr. Chen’s research interests lie in genetic epidemiology and population genetics. He has been developing new methods for genetic risk prediction and applying these methods to real data analyses. These methods include improved polygenic prediction models by leveraging genetic ancestry information, genetic risk prediction models based on pleiotropic effects, and prediction models using genetic factors, environmental factors, family history and interactions between these risk factors. He also developed methods for ancestry inference with better efficiency than current methods. His recent research focuses on applying these methods in combination with other existing methods to understand the genetic architecture of psychiatric disorders, including posttraumatic stress disorder (PTSD), bipolar disorder, and electroencephalography (EEG) phenotypes among schizophrenia and bipolar disorder patients.

As a computational scientist at JAX, Wan-Ping focuses on bioinformatics tool development and structural variation (SV) detection. Previously, Wan-Ping worked as a senior lead scientist at Seven Bridges, overseeing R&D projects. Wan-Ping is also an active member of the 1000 Genomes Project and her primary contributions were to the alignment and SV detection parts of the project. Prior to Seven Bridges, she was a postdoctoral and senior research associate at Boston College for five years and a visiting scholar at Carnegie Mellon University in 2008. She earned her Ph.D. in Electrical Engineering from National Taiwan University where she received the school’s outstanding research award. Wan-Ping is known by several bioinformatics tools, such as a short read aligner MOSAIK, mobile-element caller TANGRAM, SIMD Smith-Waterman implementation and population-based graph representation short read aligner.

黃海亮博士2012年畢業於約翰霍普金斯大學醫學院生物醫學工程系，師從Joel Bader博士，主要研究方向是計算生物學、系統生物學以及人類遺傳學。畢業後，黃博士加入麻省總醫院Mark Daly博士的研究團隊，從事人類基因組學研究。黃博士通過測序和分型分析人類基因組，結合生物網絡和系統生物學的手段，找出和疾病相關的遺傳信息，並研究疾病發生的機理。黃博士的研究成果發表在包括Nature、Cell、Genome Research、PLoS Genetics 等多家期刊，並擁有美國專利一項。其中關於全基因組關聯研究方法的文章 (GWiS) 被廣泛用於尋找與心血管疾病、精神分裂症、自閉症、老年癡呆等遺傳疾病有關的基因。

Yen-Feng Lin is a Doctor of Science candidate in Epidemiology at the Harvard School of Public Health. He is also a board-certified psychiatrist in Taiwan. Yen-Feng’s research interest is focused on population genetics and genetic epidemiology of psychiatric disorders. He is working with Dr. Jordan Smoller studying the genetic overlaps between personality traits and cardiovascular disease (CVD) and the impact of personality traits on the association between genetics and CVD.

Yen-Feng received his MD degree from National Yang-Ming University, Taiwan. He received his MS degree in Epidemiology from the Harvard School of Public Health, and his MHS degree in Mental Health from the Johns Hopkins School of Public Health.

林玉祥博士，DNArails Co., Ltd. 共同創辦人暨執行長。

目前正在生物資訊領域創業，共同創辦DNArails，希望用資訊技術推動生命健康事業的創新，建立基因資料分析平台，協助臨床科學發展。

多年於中央研究院從事生物資訊領域基因定序分析相關研究工作，參與過疾病與癌症方面的研究。致力於生物資料探勘與機器學習，尋找人類基因與癌症的關係。畢業於交通大學生物資訊所。

MAJOR RESEARCH INTERESTS:

My major research interests are environmental and molecular epidemiology, with a special focus on the interaction between environmental exposures and common genetic variation and epigenetic modifications.

EDUCATION:

Environmental and Occupational Medicine and Epidemiology, D.S. Harvard School of Public Health, Boston, MA environmental and Occupational Medicine and Epidemiology, M.S. Harvard School of Public Health, Boston, MA Public Health, B.S. National Taiwan University, Taipei, Taiwan

ACADEMIC APPOINTMENTS:

Assistant Professor, Institute of Environmental Health, National Taiwan University

Dr. Seow Wei Jie is an Assistant Professor at the Saw Swee Hock School of Public Health at the National University of Singapore. Previously, she completed her postdoctoral training in the Division of Cancer Epidemiology and Genetics (DCEG) at the U.S. National Cancer Institute (NCI). Dr. Seow has a doctorate in Environmental and Molecular Epidemiology from the Harvard T.H. Chan School of Public Health. Her current research focuses on the environmental and molecular epidemiology of chronic diseases, particularly cancers of the lung, prostate and colo-rectum. She has experience working with the Female Lung Cancer Consortium in Asia and has conducted a series of genome-wide association studies (GWAS) and epigenome-wide DNA methylation evaluations.

Yen-Chen recently graduated with a doctoral degree in genetic epidemiology and statistical genetics from Harvard T.H. Chan School of Public Health. Her research focused on developing and applying statistical methods to a range of human -omics data, including genomics, epigenomics, and metabolomics. She will be working as a post-doctoral fellow at Mass General Hospital to study the genetic underpinnings of psychiatric disorders, with a particular focus on cross-phenotype associations using GWAS data.

陳卓逸博士是台灣亞奧運游泳運動員，前男子游泳全國最高紀錄保持人暨中華民國國光獎章得主。畢業於國立臺灣大學資訊工程學系，後取得該校生醫電子與資訊學碩士學位以及基因體與系統生物學博士學位（與中央研究院合授）。曾赴美國匹茲堡大學擔任訪問學者，後於波士頓達納法伯癌症研究中心進行博士後研究。現為國立陽明大學生醫資訊研究所助理教授。陳博士為台灣演化與計算生物學會創社會員，其研究領域包含基因體學、網路生物學與時間生物學，亦致力於推廣資訊教育與培育跨領域年輕科學人才。

聯絡人資訊：

胡惠涵 博士 (02)2789-8756

主辦單位：

中央研究院基因體研究中心

台灣流行病學學會

網站資訊：

最佳瀏覽效果的螢幕解析度為1024x768，瀏覽器建議IE 10, Firefox 25.0, Chrom 30.0, Safari 6.0以上。

Copyright © 2017 中央研究院基因體研究中心